LOCUS       NC_003888              26454 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    .
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2023-11-22 14:16:39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 7682906
            Orig. end    :: 7709360
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..26454
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16454]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16454
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..26454
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..26454
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="24"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     gene            complement(32..547)
                     /db_xref="GeneID:1102357"
                     /gene_synonym="SC1B2.25c"
                     /locus_tag="SCO6919"
     CDS             complement(32..547)
                     /codon_start=1
                     /db_xref="GeneID:1102357"
                     /gene_synonym="SC1B2.25c"
                     /locus_tag="SCO6919"
                     /note="SC1B2.25c, unknown, len: 171 aa. The N-terminus of
                     the predicted protein product of this CDS is hydrophilic."
                     /product="hypothetical protein"
                     /protein_id="NP_630986.1"
                     /transl_table=11
                     /translation="MSGVSKGSPATGGPGLVRRRGTPDEEAATEGGSQPAGTQDKPEQP
                     RTRRRTYQRRQRPHVRNTRFSDDELHLVTAGAQAAGLTLAGFLARAALSAARDLERTAS
                     AVADEREVIAEFFAARRHLGHIGNNLNQLARAVNAGARPDELDVVIAATDRAVQRVQRA
                     TDRLLHQD"
     PFAM_domain     complement(68..187)
                     /aSDomain="MobC"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05713.14"
                     /description="Bacterial mobilisation protein (MobC)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6919_0939"
                     /evalue="1.80E-08"
                     /label="SCO6919"
                     /locus_tag="SCO6919"
                     /protein_end="160"
                     /protein_start="120"
                     /score="34.7"
                     /tool="antismash"
                     /translation="RHLGHIGNNLNQLARAVNAGARPDELDVVIAATDRAVQRV"
     gene            complement(640..972)
                     /db_xref="GeneID:1102358"
                     /gene_synonym="SC1B2.26c"
                     /locus_tag="SCO6920"
     CDS             complement(640..972)
                     /codon_start=1
                     /db_xref="GeneID:1102358"
                     /gene_synonym="SC1B2.26c"
                     /locus_tag="SCO6920"
                     /note="SC1B2.26c, doubtful CDS, len: 110 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_630987.1"
                     /transl_table=11
                     /translation="MRLNSAKPQLKARTRKGGPVPRRATAPVRRYAVTPHPPRSSQPTT
                     ADADAWADVLVRRQLLHAVVLTPTGQWLVQDRPNGPVRVLASPADVLALAATIQQRTRS
                     TRSESR"
     gene            complement(1151..2881)
                     /db_xref="GeneID:1102359"
                     /gene_synonym="SC1B2.27c"
                     /locus_tag="SCO6921"
     CDS             complement(1151..2881)
                     /codon_start=1
                     /db_xref="GeneID:1102359"
                     /gene_synonym="SC1B2.27c"
                     /locus_tag="SCO6921"
                     /note="SC1B2.27c, possible membrane protein, len: 576 aa.
                     Contains a 4xPTTPQSGTDTTQDQG repeat sequence and multiple
                     possible membrane spanning hydrophobic domains."
                     /product="hypothetical protein"
                     /protein_id="NP_630988.1"
                     /transl_table=11
                     /translation="MTHPVLAFGATSGLPLLLAAIVPAVLALVLTAWTVRRGRARPQKR
                     DGGPAVKVAAVAALGCTAYSADTSWQFAADYLDMAGTAERAAMFAAAEMALFATALMAR
                     QNLAVQGAPGLPGTLVWVITTVQVIPAYAESGPVGGTVRAFVGPVMAAMLWHLAMGIEL
                     RLRTPGAASHGLIAVLGREARERLLSRLGIAARDRDAAQITRDRATTRAVTLAARLAER
                     TPEQQQSRRGRRLTRRLSKAVGRASVGTDPLQRAQLLDQLAARRHALALATVQLPSPWS
                     PAHSSASAATVPAQPPSNEPVPAPGHDGSDEPVRDRGPRTPRGPGPEETDPEATVGAGT
                     EGDATGTAAGTKPREDGAVPGTEPAGPEAAARDAAAMRTDHNAREVAAQGTDSHPGPGT
                     AKSGTESTEDRGPTTPQSGTDTTQDQGPTTPQSGTDTTQDQGPTTPQSGTDTTQDQGPT
                     TPQSGTDTTQDQGRKVPLRRKPPRPSRTKNKGKRARSRSPQTERQARELGESERQLVRE
                     VRPHVPALLERDGNGAITRVQLREIIRRQGLTGVGNDRLGLVLQELRNGDVTTTRSTAR
                     "
     repeat_region   complement(1469..1688)
                     /gene_synonym="SC1B2.27c"
                     /locus_tag="SCO6921"
                     /note="repeat region containing the sequence
                     CCGACCACCCCACAGTCCGGGACCGACACCACCCAGGACCAAGGA repeated
                     perfectly 4x and degenerately 1x:
                     (CACCGCAAAGTCCGGGACCGAGAGCACCGAGGACCGAGGA)."
     gene            complement(2878..3519)
                     /db_xref="GeneID:1102360"
                     /gene_synonym="SC1B2.28c"
                     /locus_tag="SCO6922"
     CDS             complement(2878..3519)
                     /codon_start=1
                     /db_xref="GeneID:1102360"
                     /gene_synonym="SC1B2.28c"
                     /locus_tag="SCO6922"
                     /note="SC1B2.28c, unknown, len: 213 aa. The N-terminus of
                     this protein is highly similar to several proposed
                     regulatory proteins e.g. Streptomyces coelicolor
                     TR:Q9XAL5(EMBL:AL079355) transcriptional regulator,
                     SC4C6.25 (81 aa), fasta scores opt: 197 z-score: 226.2 E():
                     3.9e-05 41.1% identity in 73 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_630989.1"
                     /transl_table=11
                     /translation="MRHITTHDAPATGLRSIADTSWHVRGACHGMDIEDADAVFFPGPR
                     DHEEIAEAKELCGWCPVRRACLDFALENVLKEGVWGGLTEAERRPLHDNLHQRLDYRRV
                     TALFYGRDVHLTEAERQVVIDHAYVRGWQPDRLAAALQISHKHARDLLRQAANKVFDRD
                     RTYGVPRRKKKRKKPSKAEGTPTPAAPGTQQPAGRPAASPPAQAPLGKAA"
     PFAM_domain     complement(3247..3456)
                     /aSDomain="Whib"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02467.19"
                     /description="Transcription factor WhiB"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6922_0940"
                     /evalue="2.00E-20"
                     /label="SCO6922"
                     /locus_tag="SCO6922"
                     /protein_end="91"
                     /protein_start="21"
                     /score="73.3"
                     /tool="antismash"
                     /translation="WHVRGACHGMDIEDADAVFFPGPRDHEEIAEAKELCGWCPVRRAC
                     LDFALENVLKEGVWGGLTEAERRPL"
     regulatory      complement(3527..3530)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(3680..4396)
                     /db_xref="GeneID:1102361"
                     /gene_synonym="SC1B2.29c"
                     /locus_tag="SCO6923"
     CDS             complement(3680..4396)
                     /codon_start=1
                     /db_xref="GeneID:1102361"
                     /gene_synonym="SC1B2.29c"
                     /locus_tag="SCO6923"
                     /note="SC1B2.29c, unknown, len: 238 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_630990.1"
                     /transl_table=11
                     /translation="MDRREIAALLAYIGRLDPRSIRTDEGEARDQLAQWHELLGDVPMA
                     TSHGWDARVAARQHYRTSPYQIQPADVVRPWESYRRNRLALHWDPTPSADPDDQAAWTA
                     ELVGTRRAVAAGTAQPAYAPAITSSQEELNPRLQARLNEIGSCIPPAARAALAPFRPAR
                     AAREAAVAQGLPDALSVRCEWCLAPVGEPCRRRRIGPNDRVRTITPRTDPHPGRLDLAA
                     AKQAQRTEKAQQPALA"
     gene            complement(4399..5295)
                     /db_xref="GeneID:1102362"
                     /gene_synonym="SC1B2.30c"
                     /locus_tag="SCO6924"
     CDS             complement(4399..5295)
                     /codon_start=1
                     /db_xref="GeneID:1102362"
                     /gene_synonym="SC1B2.30c"
                     /locus_tag="SCO6924"
                     /note="SC1B2.30c, possible DNA-binding protein, len: 298
                     aa. Contains a helix-turn-helix motif situated between
                     residues 66..87 (+2.59 SD)."
                     /product="DNA-binding protein"
                     /protein_id="NP_630991.1"
                     /transl_table=11
                     /translation="MSSEARDWVWEHSSSRGAARLVLLSIADRVADEQCVSWASLSSLA
                     KRTRASVSTVREAIGRLLLAGELEQLDDLVGPQRSTVYRLPLAAEAVAQALRQQQEADG
                     ATAVADEPAAPAALRLSVLRRYGIRQREVPESPARVRKPAVPETGRSRRKPAPRRAGNR
                     HRDVPATGTQNRSEPNLNRRYSSSGAAVTSATEWQVDPATHTWARQQGHLDRLGAQGLH
                     AADAKWRAHRAGHAPRPAEAWAADWRSWITREHAPNRPNLYAVPGKNTTSSSGMTRAEK
                     HTAALLAALDEPTGTEG"
     regulatory      complement(4404..4408)
                     /gene_synonym="SC1B2.30c"
                     /locus_tag="SCO6924"
                     /regulatory_class="ribosome_binding_site"
     regulatory      complement(5300..5306)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(5930..6142)
                     /db_xref="GeneID:1102363"
                     /gene_synonym="SC1B2.31c"
                     /locus_tag="SCO6925"
     CDS             complement(5930..6142)
                     /codon_start=1
                     /db_xref="GeneID:1102363"
                     /gene_synonym="SC1B2.31c"
                     /locus_tag="SCO6925"
                     /note="SC1B2.31c, doubtful CDS (membrane protein), len: 70
                     aa. Contains a TTA leucine codon, possible target for bldA
                     regulation. Contains possible hydrophobic membrane spanning
                     region"
                     /product="hypothetical protein"
                     /protein_id="NP_630992.1"
                     /transl_table=11
                     /translation="MGAPSFDREYFSKFWILAYLPHMFAILGPVSSPTLDKTSVTRRAQ
                     IPGLTEGRIISCDAQGMIQLPAGGR"
     misc_feature    complement(6083..6085)
                     /gene_synonym="SC1B2.31c"
                     /locus_tag="SCO6925"
                     /note="TTA /leucine codon, possible target for bldA
                     regulation."
     misc_feature    complement(6083..6085)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6210..6224)
                     /note="TFBS match to ZuR, Zinc-responsive repressor,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            6724..7548
                     /db_xref="GeneID:1102364"
                     /gene_synonym="SC1B2.32"
                     /locus_tag="SCO6926"
     CDS             6724..7548
                     /codon_start=1
                     /db_xref="GeneID:1102364"
                     /gene_synonym="SC1B2.32"
                     /locus_tag="SCO6926"
                     /note="SC1B2.32, unknown, len: 274 aa. Weakly similar to
                     several including: Streptomyces coelicolor TR:CAB53276
                     (EMBL:AL109972) DNA-binding protein, SCJ9A.15C (290 aa),
                     fasta scores opt: 225 z-score: 274.7 E(): 7.7e-08 29.0%
                     identity in 238 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_630993.1"
                     /transl_table=11
                     /translation="MCGAIKDGGGEGESTGIGALLRVFRAAAGTTLGRPILQREVADAL
                     HRSERWYRDLEGGVITRPLTRHELDTIGTLLGLDRVQRRALFLVSNGGGLSSPETQEPP
                     RISDELRLLLDQQPFPAYVIDATWNVLAVNTSMAALFPWSTAPGANLMRWLLLSAEARD
                     QHLHWEADAEVCVCMLRDAAVDRPHDPDLQQLISDSRQNPAVRDLWTRGAADFADHYDG
                     HVLQMTLPLFDGQVTELVTHVLQPAGLPGCRMTILTQRAPQEPSGRQPVQAT"
     PFAM_domain     6772..6981
                     /aSDomain="HTH_31"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13560.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6926_0941"
                     /evalue="2.10E-06"
                     /label="SCO6926"
                     /locus_tag="SCO6926"
                     /protein_end="86"
                     /protein_start="16"
                     /score="28.1"
                     /tool="antismash"
                     /translation="IGALLRVFRAAAGTTLGRPILQREVADALHRSERWYRDLEGGVIT
                     RPLTRHELDTIGTLLGLDRVQRRAL"
     PFAM_domain     7042..7506
                     /aSDomain="MLTR_LBD"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF17765.4"
                     /description="MmyB-like transcription regulator ligand
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6926_0942"
                     /evalue="2.40E-24"
                     /label="SCO6926"
                     /locus_tag="SCO6926"
                     /protein_end="261"
                     /protein_start="106"
                     /score="86.5"
                     /tool="antismash"
                     /translation="SDELRLLLDQQPFPAYVIDATWNVLAVNTSMAALFPWSTAPGANL
                     MRWLLLSAEARDQHLHWEADAEVCVCMLRDAAVDRPHDPDLQQLISDSRQNPAVRDLWT
                     RGAADFADHYDGHVLQMTLPLFDGQVTELVTHVLQPAGLPGCRMTILTQRA"
     gene            complement(8875..9999)
                     /db_xref="GeneID:1102365"
                     /gene_synonym="SC1B2.33c"
                     /locus_tag="SCO6927"
     CDS             complement(8875..9999)
                     /codon_start=1
                     /db_xref="GeneID:1102365"
                     /gene_synonym="SC1B2.33c"
                     /locus_tag="SCO6927"
                     /note="SC1B2.33c, unknown, len: 374 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_630994.1"
                     /transl_table=11
                     /translation="MDVGQIAKRFPLVARPRPACLPLAERVREITDLAAAAERDGNVTS
                     ATVALNKAALIASDCGMPDLARTLCWRHAEAVLRAQPLGAQEARYALEPLVNLARLRIR
                     DGDGHGAYHLLDSLNRAVRSKTEAVIDGRTTPLQHLTTSAADHQQVCQWLWTVLLGDGT
                     RALVAAGEWDRARAHSRQHRGIGQRLFDGRQVEVLVRCLGEQPSDALMFLHTSQLVEPW
                     EQSVAAALTVLCHRAADEHPVEPVDKMVQHYLALDSAPELAVFRSRVGLVVLDLSPKTR
                     QAEAMRRLTCEAMRQTDGYVARDVLAHPVCREALGHGEHRTLSAAVASAGLGQGHIPEP
                     LTQALLGAASVSADVWERHVTRRASPGSSRNLDS"
     gene            complement(10001..12091)
                     /db_xref="GeneID:1102366"
                     /gene_synonym="SC1B2.34c"
                     /locus_tag="SCO6928"
     CDS             complement(10001..12091)
                     /codon_start=1
                     /db_xref="GeneID:1102366"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SC1B2.34c"
                     /locus_tag="SCO6928"
                     /note="SC1B2.34c, possible O-methyltransferase, len: 696
                     aa. Contains a central region which is similar to many
                     protein-L-isoaspartate O-methyltransferases e.g.
                     Escherichia coli SW:PIMT_ECOLI (EMBL:M63493) (207 aa),
                     fasta scores opt: 301 z-score: 340.3 E(): 1.7e-11 31.5%
                     identity in 213 aa overlap and Streptomyces coelicolor
                     TR:CAB71208 (EMBL:AL138538) SC6D10.13C (324 aa), fasta
                     scores opt: 442 z-score: 493.8 E(): 4.8e-20 36.9% identity
                     in 306 aa overlap. Contains a Pfam match to entry PF01135
                     PCMT, Protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase (PCMT)."
                     /product="O-methyltransferase"
                     /protein_id="NP_630995.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.4e-29, bitscore:
                     100.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 6.1e-44, bitscore: 149.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADEWPQRLIRFTDWSHAEATAVEHLLPVLIAQESELAQWSFLR
                     KHPWWRLRYRPACPDSAKALDAALDELVDAGVLASWTRGIYEPEETAFGGPAAMKIAHA
                     LFHYDSRHLLDEAARQQTVSGPRLGRRELAVLLLSVAMRAAGLDWYEQGDVWARIAAER
                     SGDEVRSPQRHRAAVHRLMTVDVSTTSRSVARGRLAPLAEWIATFEWFGQQLADLNRQG
                     RLERGLRAVIAHHGIFHFNRLGLAAQDQHTLSTLAKEVVMGTSDNAASTQAEGAPGATV
                     NGVNSDTIEAPSADRLRAQLIDHLVETGCVRTPRVEEAMRTVPRHLFVPNAPLEKAYGN
                     APVDTKFDGSGRSISCASQPDIVAMMLEQLDVQPGQKILELGAGTGFNAGLLGYLVGET
                     GHVTTIDVDEDIVAGARGGLAAAGIHNVEVILGDGAVGHTPNAPYDRIEATVGAHGVPH
                     AWLDQLAPGGRLLTPLRLRGSVSRSIAFENQDGAWRSVGSQMNTFMPLRRGIADDPRLF
                     VPLDPDHTVTLVTNGDQKVDADALGDIFRQPRTEAWTDVTFRGPESAEYLELWLTCAMP
                     NGLSRMPAKNEAIEKGLVTAPYPSSTAVFEDGTLTYLTRRPYAKKAPDGATLYEFGVIG
                     HGPDAEALAGDVADQIRAWDQDFRALDVGFEIQPLDAAPLAPKPGRFAFDNPLNRIVIE
                     WQ"
     aSDomain        complement(10007..11212)
                     /aSDomain="TIGR04364"
                     /aSTool="tigrfam"
                     /description="methyltran_FxLD: methyltransferase, FxLD
                     system"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6928_0112"
                     /evalue="2.20E-159"
                     /identifier="TIGR04364"
                     /label="SCO6928"
                     /locus_tag="SCO6928"
                     /protein_end="695"
                     /protein_start="293"
                     /score="528.7"
                     /tool="antismash"
                     /translation="ADRLRAQLIDHLVETGCVRTPRVEEAMRTVPRHLFVPNAPLEKAY
                     GNAPVDTKFDGSGRSISCASQPDIVAMMLEQLDVQPGQKILELGAGTGFNAGLLGYLVG
                     ETGHVTTIDVDEDIVAGARGGLAAAGIHNVEVILGDGAVGHTPNAPYDRIEATVGAHGV
                     PHAWLDQLAPGGRLLTPLRLRGSVSRSIAFENQDGAWRSVGSQMNTFMPLRRGIADDPR
                     LFVPLDPDHTVTLVTNGDQKVDADALGDIFRQPRTEAWTDVTFRGPESAEYLELWLTCA
                     MPNGLSRMPAKNEAIEKGLVTAPYPSSTAVFEDGTLTYLTRRPYAKKAPDGATLYEFGV
                     IGHGPDAEALAGDVADQIRAWDQDFRALDVGFEIQPLDAAPLAPKPGRFAFDNPLNRIV
                     IEW"
     misc_feature    complement(10559..11203)
                     /gene_synonym="SC1B2.34c"
                     /locus_tag="SCO6928"
                     /note="Pfam match to entry PF01135 PCMT,
                     Protein-L-isoaspartate(D-aspartate) O-methyltransferase
                     (PCMT), score 119.30, E-value 7.2e-32"
     PFAM_domain     complement(10646..11197)
                     /aSDomain="PCMT"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01135.22"
                     /description="Protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase (PCMT)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6928_0944"
                     /evalue="1.50E-43"
                     /label="SCO6928"
                     /locus_tag="SCO6928"
                     /protein_end="482"
                     /protein_start="298"
                     /score="149.1"
                     /tool="antismash"
                     /translation="AQLIDHLVETGCVRTPRVEEAMRTVPRHLFVPNAPLEKAYGNAPV
                     DTKFDGSGRSISCASQPDIVAMMLEQLDVQPGQKILELGAGTGFNAGLLGYLVGETGHV
                     TTIDVDEDIVAGARGGLAAAGIHNVEVILGDGAVGHTPNAPYDRIEATVGAHGVPHAWL
                     DQLAPGGRLLTPLRLRGSVSR"
     PFAM_domain     complement(11309..12031)
                     /aSDomain="Lant_dehydr_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF14028.9"
                     /description="Lantibiotic biosynthesis dehydratase C-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6928_0943"
                     /evalue="2.70E-33"
                     /label="SCO6928"
                     /locus_tag="SCO6928"
                     /protein_end="261"
                     /protein_start="20"
                     /score="116.1"
                     /tool="antismash"
                     /translation="ATAVEHLLPVLIAQESELAQWSFLRKHPWWRLRYRPACPDSAKAL
                     DAALDELVDAGVLASWTRGIYEPEETAFGGPAAMKIAHALFHYDSRHLLDEAARQQTVS
                     GPRLGRRELAVLLLSVAMRAAGLDWYEQGDVWARIAAERSGDEVRSPQRHRAAVHRLMT
                     VDVSTTSRSVARGRLAPLAEWIATFEWFGQQLADLNRQGRLERGLRAVIAHHGIFHFNR
                     LGLAAQDQHTLSTLAKEVV"
     aSDomain        complement(11309..12052)
                     /aSDomain="TIGR03891"
                     /aSTool="tigrfam"
                     /description="thiopep_ocin: thiopeptide-type bacteriocin
                     biosynthesis domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6928_0113"
                     /evalue="3.80E-47"
                     /identifier="TIGR03891"
                     /label="SCO6928"
                     /locus_tag="SCO6928"
                     /protein_end="261"
                     /protein_start="13"
                     /score="159.4"
                     /tool="antismash"
                     /translation="TDWSHAEATAVEHLLPVLIAQESELAQWSFLRKHPWWRLRYRPAC
                     PDSAKALDAALDELVDAGVLASWTRGIYEPEETAFGGPAAMKIAHALFHYDSRHLLDEA
                     ARQQTVSGPRLGRRELAVLLLSVAMRAAGLDWYEQGDVWARIAAERSGDEVRSPQRHRA
                     AVHRLMTVDVSTTSRSVARGRLAPLAEWIATFEWFGQQLADLNRQGRLERGLRAVIAHH
                     GIFHFNRLGLAAQDQHTLSTLAKEVV"
     gene            complement(12110..13369)
                     /db_xref="GeneID:1102367"
                     /gene_synonym="SC1B2.35c; SC1G8.01c"
                     /locus_tag="SCO6929"
     CDS             complement(12110..13369)
                     /codon_start=1
                     /db_xref="GeneID:1102367"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     403.5; E-value: 1.6e-122)"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SC1B2.35c; SC1G8.01c"
                     /locus_tag="SCO6929"
                     /note="SC1G8.01c, unknown, partial CDS,len: >270 aa. Weakly
                     similar to Bacillus subtilis SW:SPAC_BACSU (EMBL:M86869)
                     subtilin biosynthetic protein, possibly involved in export,
                     SpaC (441 aa), fasta scores opt: 319 z-score: 378.0 E():
                     1.4e-13 29.0% identity in 245 aa overlap.; SC1B2.35c,
                     unknown, partial CDS, len: >181 aa. Similar to Streptomyces
                     coelicolor TR:CAB55532 (EMBL:AL117322) hypothetical 49.0 kd
                     protein, SCF1.12 (466 aa), fasta scores opt: 238 z-score:
                     283.2 E(): 2.6e-08 31.1% identity in 180 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_733718.1"
                     /sec_met_domain="LANC_like (E-value: 1.1e-65, bitscore:
                     220.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLRDSALATADTIAERLASPQDIRELHHRQGWWPQSLAHGAAGV
                     ALLHIERARTDQGPWQRAHDWLACAAAEPAVGGPDSHLYYGAPALAFALHAAADRPGRY
                     ARALDTLDRYVTKAIRDRLAGAHARMDRGEMPALAEFDAIRGLSGMGGLLLHRDVHTDV
                     LREVLTYLVRLTEPVKHDGEVLPGWWSHLAPSGTISPEYPEGHANNGVAHGIGGPLAVL
                     SLAARRGITVDGHLDAITGILTWLDHWQQDGPAGPWWPYWITREQLRSGTTGPGPSRPS
                     WCYGTAGFARVQQLAALALKDPARQHAAEFALLRAMTDSGQLDATVDMSLCHGFAGLAH
                     ITRLAADDALTPGLTACLPRLLAPITDTAPGTLADSLISPPSGGDIGLLEGAAGTALAL
                     HSFHTGTPSASGWETCFLTN"
     PFAM_domain     complement(12119..13273)
                     /aSDomain="LANC_like"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05147.16"
                     /db_xref="GO:0031179"
                     /description="Lanthionine synthetase C-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6929_0945"
                     /evalue="2.90E-67"
                     /gene_ontologies="GO:0031179: peptide modification"
                     /label="SCO6929"
                     /locus_tag="SCO6929"
                     /protein_end="417"
                     /protein_start="32"
                     /score="226.8"
                     /tool="antismash"
                     /translation="WWPQSLAHGAAGVALLHIERARTDQGPWQRAHDWLACAAAEPAVG
                     GPDSHLYYGAPALAFALHAAADRPGRYARALDTLDRYVTKAIRDRLAGAHARMDRGEMP
                     ALAEFDAIRGLSGMGGLLLHRDVHTDVLREVLTYLVRLTEPVKHDGEVLPGWWSHLAPS
                     GTISPEYPEGHANNGVAHGIGGPLAVLSLAARRGITVDGHLDAITGILTWLDHWQQDGP
                     AGPWWPYWITREQLRSGTTGPGPSRPSWCYGTAGFARVQQLAALALKDPARQHAAEFAL
                     LRAMTDSGQLDATVDMSLCHGFAGLAHITRLAADDALTPGLTACLPRLLAPITDTAPGT
                     LADSLISPPSGGDIGLLEGAAGTALALHSFHTGTPSASGWETCFL"
     gene            complement(13356..16454)
                     /db_xref="GeneID:1102368"
                     /gene_synonym="SC1G8.02c"
                     /locus_tag="SCO6930"
     CDS             complement(13356..16454)
                     /codon_start=1
                     /db_xref="GeneID:1102368"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     1058.2; E-value: 0.0)"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SC1G8.02c"
                     /locus_tag="SCO6930"
                     /note="SC1G8.02c, unknown, len: 1032 aa. Similar to a
                     number of proteins involved in the posttranslational
                     modification of the lantibiotics e.g. Bacillus subtilis
                     SW:SPAB_BACSU (EMBL:L24075) subtilin biosynthesis protein,
                     SpaB (1030 aa), fasta scores opt: 516 z-score: 571.0 E():
                     2.4e-24 22.1% identity in 988 aa overlap. Also similar to
                     Streptomyces coelicolor TR:CAB55531 (EMBL:AL117322)
                     hypothetical 114.5 kd protein, SCF1.11 (1053 aa), fasta
                     scores opt: 884 z-score: 982.0 E(): 0 30.6% identity in
                     1081 aa overlap. Contains a TTA leucine codon, possible
                     target for bldA regulation"
                     /product="hypothetical protein"
                     /protein_id="NP_630996.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.1e-201,
                     bitscore: 670.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.7e-16,
                     bitscore: 58.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.5e-27, bitscore:
                     94.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSRKDCPLYRCADTALVRAARSARLPLPAWPDLTDDTPDCEVRW
                     QTWLRDVWSLSEAADSIEQASPLLAQQVQALCSVASPETRQLRRAVVSVMRYLLRMTGR
                     ATPNGLFAGIAPASFGERPGWSWGEWHRPVIRADGDWIADLVARLEADPELLRHLHVMA
                     NNTILIRGDRLIMPYPPRSCRTDGSPAAEVSVRYTSAVRIAVDAAASPVPVHAVVALMR
                     SEFPDVPADRVEGLVSSLVERGVLISSLHAPSATLDALDHLVEQAEAAAAPSATGLVAD
                     LRTVRDAIARHNQVLAPADGRRLRTALRRKMTALSSVKAQPFTLDLRMDCSLTLPPQVA
                     REAEQAATVLARLSAYPFGTPAWKDFHNRFFERYGINSLVPVRDLVDPDVGLGFPVGYR
                     DAQPEQGEALTAREQRLLSLAQAAVLDGRDEIHLDEDLIRTLTVGDRNAPHVPAHTELR
                     FRIRATSQEALESGDFVLHGIAPSRGIGTTIGRSLGLLAPDEQARVAVMLEELPVNTPG
                     AVPTQVSFTPLDRGDTNVTRVTELLPAVISLAEHRPVDARTIPLDDLAVGCDRRRLYLV
                     SLSRACLLDPMTLHALDLRGHTPPLGRFLTEISRAQTAVLTVFPWASATALPYLPRVRY
                     GRAILSPARWRLDRSELPDRRASWGEWHKAADEWRARRRVPDEVAVAEGDQLLPLDLSE
                     RAHLALLRAHLDTHESVILTEAESEEGWFDGRSHEIIAPMTAVRPPQWPAVPPVTADQL
                     VTRDHGYLPGAASWLLVKLYGHVDRQPEILADHLPALLGQWDEPPTWWYMRYRDPRWHL
                     RLRIAVPSEQDFALTARRVSSWANGLRRAGLLADMQFATSYPETGRWGPGPLMNLAEDV
                     FAADSRALAVQFAQSSRPHQQVLAAANFVSVAAAFTGSTAAGMNWLIAHGRITDPRPMD
                     RTVRGQALRLADPADGWAALRAAPGGDAIASAWSERDAALARYRQKLDAFGGIDLDLVL
                     DSLLHAHHIRAAGIDKDDERMCVRLAHAAAMAWTHRGDHHESA"
     PFAM_domain     complement(13398..14156)
                     /aSDomain="Lant_dehydr_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF14028.9"
                     /description="Lantibiotic biosynthesis dehydratase C-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6930_0947"
                     /evalue="3.00E-29"
                     /label="SCO6930"
                     /locus_tag="SCO6930"
                     /protein_end="1019"
                     /protein_start="766"
                     /score="102.8"
                     /tool="antismash"
                     /translation="WLLVKLYGHVDRQPEILADHLPALLGQWDEPPTWWYMRYRDPRWH
                     LRLRIAVPSEQDFALTARRVSSWANGLRRAGLLADMQFATSYPETGRWGPGPLMNLAED
                     VFAADSRALAVQFAQSSRPHQQVLAAANFVSVAAAFTGSTAAGMNWLIAHGRITDPRPM
                     DRTVRGQALRLADPADGWAALRAAPGGDAIASAWSERDAALARYRQKLDAFGGIDLDLV
                     LDSLLHAHHIRAAGIDKDDERMCVRLAHAAA"
     aSDomain        complement(13401..14156)
                     /aSDomain="TIGR03891"
                     /aSTool="tigrfam"
                     /description="thiopep_ocin: thiopeptide-type bacteriocin
                     biosynthesis domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6930_0114"
                     /evalue="1.60E-66"
                     /identifier="TIGR03891"
                     /label="SCO6930"
                     /locus_tag="SCO6930"
                     /protein_end="1018"
                     /protein_start="766"
                     /score="222.9"
                     /tool="antismash"
                     /translation="WLLVKLYGHVDRQPEILADHLPALLGQWDEPPTWWYMRYRDPRWH
                     LRLRIAVPSEQDFALTARRVSSWANGLRRAGLLADMQFATSYPETGRWGPGPLMNLAED
                     VFAADSRALAVQFAQSSRPHQQVLAAANFVSVAAAFTGSTAAGMNWLIAHGRITDPRPM
                     DRTVRGQALRLADPADGWAALRAAPGGDAIASAWSERDAALARYRQKLDAFGGIDLDLV
                     LDSLLHAHHIRAAGIDKDDERMCVRLAHAA"
     PFAM_domain     complement(14352..16286)
                     /aSDomain="Lant_dehydr_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04738.16"
                     /description="Lantibiotic dehydratase, N terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6930_0946"
                     /evalue="1.60E-205"
                     /label="SCO6930"
                     /locus_tag="SCO6930"
                     /protein_end="701"
                     /protein_start="56"
                     /score="684.1"
                     /tool="antismash"
                     /translation="EAADSIEQASPLLAQQVQALCSVASPETRQLRRAVVSVMRYLLRM
                     TGRATPNGLFAGIAPASFGERPGWSWGEWHRPVIRADGDWIADLVARLEADPELLRHLH
                     VMANNTILIRGDRLIMPYPPRSCRTDGSPAAEVSVRYTSAVRIAVDAAASPVPVHAVVA
                     LMRSEFPDVPADRVEGLVSSLVERGVLISSLHAPSATLDALDHLVEQAEAAAAPSATGL
                     VADLRTVRDAIARHNQVLAPADGRRLRTALRRKMTALSSVKAQPFTLDLRMDCSLTLPP
                     QVAREAEQAATVLARLSAYPFGTPAWKDFHNRFFERYGINSLVPVRDLVDPDVGLGFPV
                     GYRDAQPEQGEALTAREQRLLSLAQAAVLDGRDEIHLDEDLIRTLTVGDRNAPHVPAHT
                     ELRFRIRATSQEALESGDFVLHGIAPSRGIGTTIGRSLGLLAPDEQARVAVMLEELPVN
                     TPGAVPTQVSFTPLDRGDTNVTRVTELLPAVISLAEHRPVDARTIPLDDLAVGCDRRRL
                     YLVSLSRACLLDPMTLHALDLRGHTPPLGRFLTEISRAQTAVLTVFPWASATALPYLPR
                     VRYGRAILSPARWRLDRSELPDRRASWGEWHKAADEWRARRRVPDEVAVAEGDQLLPLD
                     LSERAHLALL"
     misc_feature    complement(15531..15533)
                     /gene_synonym="SC1G8.02c"
                     /locus_tag="SCO6930"
                     /note="TTA /leucine codon, possible target for bldA
                     regulation."
     misc_feature    complement(15531..15533)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(15696..15974)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SCO6930_Lanthipeptide_LanB_RRE.1"
                     /evalue="9.90E-19"
                     /identifier="RREFam001.1"
                     /label="SCO6930"
                     /locus_tag="SCO6930"
                     /protein_end="253"
                     /protein_start="160"
                     /score="58.8"
                     /tool="antismash"
                     /translation="VMANNTILIRGDRLIMPYPPRSCRTDGSPAAEVSVRYTSAVRIAV
                     DAAASPVPVHAVVALMRSEFPDVPADRVEGLVSSLVERGVLISSLHAP"
     repeat_region   complement(16541..16658)
                     /gene_synonym="SC1G8.03c"
                     /locus_tag="SCO6931"
                     /note="shares 99 % sequence identity with the duplicated
                     region: complement(4198..4315)."
     gene            complement(16541..16720)
                     /db_xref="GeneID:1102369"
                     /gene_synonym="SC1G8.03c"
                     /locus_tag="SCO6931"
     CDS             complement(16541..16720)
                     /codon_start=1
                     /db_xref="GeneID:1102369"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC1G8.03c"
                     /locus_tag="SCO6931"
                     /note="SC1G8.03c, unknown, len: 59 aa. Highly similar to
                     the upstream CDS SC1G8.04c (43 aa), fasta scores opt: 261
                     z-score: 356.0 E(): 2.7e-14 97.5% identity in 40 aa
                     overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_630997.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.4e-14, bitscore:
                     52.6, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNANTIKGQAHSPAATAGGDAFDLDISVLESDDGSATLINLTDDG
                     CGSTCSSPCATNVA"
     CDS_motif       complement(16607..16720)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNANTIKGQAHSPAATAGGDAFDLDISVLESDDGSATL"
                     /locus_tag="SCO6931_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16541..16606)
                     /prepeptide="core"
                     /locus_tag="SCO6931_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="1.60"
                     /molecular_weight="1921.1"
                     /monoisotopic_mass="1919.8"
                     /core_sequence="INLTDDGCGSTCSSPCATNVA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNANTIKGQAHSPAATAGGDAFDLDISVLESDDGSATL"
                     /leader_location="[16606:16720](-)"
                     /alternative_weights="1939.1"
                     /alternative_weights="1957.1"
                     /alternative_weights="1975.1"
     aSDomain        complement(16553..16663)
                     /aSDomain="TIGR04363"
                     /aSTool="tigrfam"
                     /description="LD_lanti_pre: FxLD family lantipeptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6931_0115"
                     /evalue="7.90E-15"
                     /identifier="TIGR04363"
                     /label="SCO6931"
                     /locus_tag="SCO6931"
                     /protein_end="56"
                     /protein_start="19"
                     /score="52.6"
                     /tool="antismash"
                     /translation="DAFDLDISVLESDDGSATLINLTDDGCGSTCSSPCAT"
     regulatory      complement(16729..16732)
                     /regulatory_class="ribosome_binding_site"
     repeat_region   complement(16758..16875)
                     /gene_synonym="SC1G8.04c"
                     /locus_tag="SCO6932"
                     /note="shares 99 % sequence identity with the duplicated
                     region: complement(3981..4098)."
     gene            complement(16758..16889)
                     /db_xref="GeneID:1102370"
                     /gene_synonym="SC1G8.04c"
                     /locus_tag="SCO6932"
     CDS             complement(16758..16889)
                     /codon_start=1
                     /db_xref="GeneID:1102370"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC1G8.04c"
                     /locus_tag="SCO6932"
                     /note="SC1G8.04c, unknown, len: 43 aa. Highly similar to
                     the downstream CDS SC1G8.03c (59 aa), fasta scrores opt:
                     261 z-score: 356.0 E(): 2.7e-14 97.5% identity in 40 aa
                     overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_630998.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1e-15, bitscore:
                     56.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNDEFDLDISVLESDDGSATLINLTDDGCGSTCSSPCATNVA"
     CDS_motif       complement(16824..16889)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MQNDEFDLDISVLESDDGSATL"
                     /locus_tag="SCO6932_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16758..16823)
                     /prepeptide="core"
                     /locus_tag="SCO6932_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="1.60"
                     /molecular_weight="1921.1"
                     /monoisotopic_mass="1919.8"
                     /core_sequence="INLTDDGCGSTCSSPCATNVA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQNDEFDLDISVLESDDGSATL"
                     /leader_location="[16823:16889](-)"
                     /alternative_weights="1939.1"
                     /alternative_weights="1957.1"
                     /alternative_weights="1975.1"
     aSDomain        complement(16770..16880)
                     /aSDomain="TIGR04363"
                     /aSTool="tigrfam"
                     /description="LD_lanti_pre: FxLD family lantipeptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6932_0116"
                     /evalue="5.80E-16"
                     /identifier="TIGR04363"
                     /label="SCO6932"
                     /locus_tag="SCO6932"
                     /protein_end="40"
                     /protein_start="3"
                     /score="56.2"
                     /tool="antismash"
                     /translation="DEFDLDISVLESDDGSATLINLTDDGCGSTCSSPCAT"
     regulatory      complement(16899..16903)
                     /regulatory_class="ribosome_binding_site"
     regulatory      16962..16965
                     /regulatory_class="ribosome_binding_site"
     gene            16967..17416
                     /db_xref="GeneID:1102371"
                     /gene_synonym="SC1G8.05"
                     /locus_tag="SCO6933"
     CDS             16967..17416
                     /codon_start=1
                     /db_xref="GeneID:1102371"
                     /gene_synonym="SC1G8.05"
                     /locus_tag="SCO6933"
                     /note="SC1G8.05, unknown, len: 149 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_630999.1"
                     /transl_table=11
                     /translation="MGVVPVVWCGQEPLEIQALPPQVEPQPPSEAILAPTVPPDSMTLM
                     SRSNGSCAVEAEAVLMPWPVILGVTGILLIGPVEHFESVCCVRPTPVGGSCVACAGLLF
                     RHENCCPEEELGTGHGSPKGEPRYAVRLPRAALEVGSSRPGPAPG"
     gene            complement(17355..17822)
                     /db_xref="GeneID:1102372"
                     /gene_synonym="SC1G8.06c"
                     /locus_tag="SCO6934"
     CDS             complement(17355..17822)
                     /codon_start=1
                     /db_xref="GeneID:1102372"
                     /gene_synonym="SC1G8.06c"
                     /locus_tag="SCO6934"
                     /note="SC1G8.06c, possible hypothetical protein, len: 155
                     aa. Contains a possible N-terminal signal sequence."
                     /product="hypothetical protein"
                     /protein_id="NP_631000.1"
                     /transl_table=11
                     /translation="MKLPTAVLAAGVALSLTTAVVGAARLRQNARHQAERHEALLAGTQ
                     LDWLNRVSTNADLAELWKPEDMKAEEYMQLMSANRLICALSVRHCLGRVRDGQLPFYSE
                     TVMSSDVCRRYWQRFGDLRAQEAKGDVRAEHFTRVLDQAAKNQPQVQPAAA"
     PFAM_domain     complement(17376..17798)
                     /aSDomain="DUF6082"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19560.2"
                     /description="Family of unknown function (DUF6082)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6934_0948"
                     /evalue="6.40E-14"
                     /label="SCO6934"
                     /locus_tag="SCO6934"
                     /protein_end="149"
                     /protein_start="8"
                     /score="51.9"
                     /tool="antismash"
                     /translation="AAGVALSLTTAVVGAARLRQNARHQAERHEALLAGTQLDWLNRVS
                     TNADLAELWKPEDMKAEEYMQLMSANRLICALSVRHCLGRVRDGQLPFYSETVMSSDVC
                     RRYWQRFGDLRAQEAKGDVRAEHFTRVLDQAAKNQPQ"
     gene            complement(17897..18472)
                     /db_xref="GeneID:1102373"
                     /gene_synonym="SC1G8.07c"
                     /locus_tag="SCO6935"
     CDS             complement(17897..18472)
                     /codon_start=1
                     /db_xref="GeneID:1102373"
                     /gene_synonym="SC1G8.07c"
                     /locus_tag="SCO6935"
                     /note="SC1G8.07c, unknown, len: 191 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_631001.1"
                     /transl_table=11
                     /translation="MTTETPQRPDIARELIARATESAAHRATRVRNQLDGVQLGRGRHT
                     DYANAKFLRRVLGEYEWPGHRLVGPAAARAAWSIALHSDHDLVFQRAATILLGRAVEVG
                     DALVHHWAHLHDRTLINTGQDQEYGTQLLLRSDRIELCPLRAPGSVDKRRVTVGLPPIA
                     VALETVRRRYMPNGSSDEVPSVVLAEAA"
     PFAM_domain     complement(17981..18343)
                     /aSDomain="DUF6624"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF20329.1"
                     /description="Family of unknown function (DUF6624)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6935_0949"
                     /evalue="4.00E-17"
                     /label="SCO6935"
                     /locus_tag="SCO6935"
                     /protein_end="164"
                     /protein_start="43"
                     /score="62.4"
                     /tool="antismash"
                     /translation="HTDYANAKFLRRVLGEYEWPGHRLVGPAAARAAWSIALHSDHDLV
                     FQRAATILLGRAVEVGDALVHHWAHLHDRTLINTGQDQEYGTQLLLRSDRIELCPLRAP
                     GSVDKRRVTVGLPPIAV"
     gene            complement(18469..19122)
                     /db_xref="GeneID:1102374"
                     /gene_synonym="SC1G8.08"
                     /locus_tag="SCO6936"
     CDS             complement(18469..19122)
                     /codon_start=1
                     /db_xref="GeneID:1102374"
                     /gene_synonym="SC1G8.08"
                     /locus_tag="SCO6936"
                     /note="SC1G8.08, unknown, len: 217 aa. Weakly similar to
                     Streptomyces coelicolor TR:CAB56672 (EMBL:AL121596)
                     hypothetical protein, SCF51A.20(252 aa), fasta scores opt:
                     111 z-score: 140.7 E(): 2.2 27.9% identity in 190 aa
                     overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_631002.1"
                     /transl_table=11
                     /translation="MRRPPTFLANEGAPASTSFAAKYPGAVYAVRRLRTDAERAEAAAL
                     VQDRQRWLTLRGLPVPAQADVPALFRDPHHTTSAGLFEDGKLLACMVPARDPGLSWGEG
                     PCLRLGHIHTLPEQPDDITRLITLWASDFAARQSLPLVRAEIPAGHTLQAEPIAALLRR
                     LTDMGWDVRGSGPGREGDRVARLELAAEHRPGLSALISCQAQAPHLAAEEGSST"
     regulatory      complement(18486..18490)
                     /gene_synonym="SC1G8.08"
                     /locus_tag="SCO6936"
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(19024..19026)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19119..19679)
                     /db_xref="GeneID:1102375"
                     /gene_synonym="SC1G8.09c"
                     /locus_tag="SCO6937"
     CDS             complement(19119..19679)
                     /codon_start=1
                     /db_xref="GeneID:1102375"
                     /gene_synonym="SC1G8.09c"
                     /locus_tag="SCO6937"
                     /note="SC1G8.09c, possible DNA-binding protein, len: 186
                     aa. Contains a possible helix-turn-helix motif situated
                     between residues 54..75 (+4.70 SD)."
                     /product="DNA-binding protein"
                     /protein_id="NP_631003.1"
                     /transl_table=11
                     /translation="MPLAPSPAGTGGTLPVTTNSAERDTVTPPVTTSAPITPLTPTLQR
                     VAQHLANGLSAQEIATQTVLSPVTVRQYLRDIRESLHCPPRCKPAVIVHRLFTTQQVAS
                     PTADRPAPSLTPEQRVLLRAVAEHSDPRDIAVAAKLAPADQRAALDQLLADTGARDATH
                     LVILAHGWKLLPTDPVARSGASQ"
     regulatory      complement(19130..19133)
                     /gene_synonym="SC1G8.09c"
                     /locus_tag="SCO6937"
                     /regulatory_class="ribosome_binding_site"
     PFAM_domain     complement(19419..19568)
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00196.22"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6937_0950"
                     /evalue="9.30E-06"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO6937"
                     /locus_tag="SCO6937"
                     /protein_end="87"
                     /protein_start="37"
                     /score="25.3"
                     /tool="antismash"
                     /translation="PLTPTLQRVAQHLANGLSAQEIATQTVLSPVTVRQYLRDIRESLH
                     CPPRC"
     gene            complement(19728..20981)
                     /db_xref="GeneID:1102376"
                     /gene_synonym="SC1G8.10c"
                     /locus_tag="SCO6938"
     CDS             complement(19728..20981)
                     /codon_start=1
                     /db_xref="GeneID:1102376"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 256; E-value:
                     9.9e-78)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC1G8.10c"
                     /locus_tag="SCO6938"
                     /note="SC1G8.10c, probable acyl-CoA dehydrogenase, len: 417
                     aa. Similar to Bacillus subtilis TR:ACDB_BACSU
                     (EMBL:U29084) acyl-CoA dehydrogenase (EC 1.3.99.-) MmgC
                     (379 aa), fasta scores opt: 651 z-score: 737.5 E(): 0 31.1%
                     identity in 380 aa overlap and Streptomyces coelicolor
                     TR:CAB87216 (EMBL:AL163641) acyl-CoA dehydrogenase,
                     SCC105.10 (386 aa), fasta scores opt: 575 z-score: 651.8
                     E(): 7.6e-29 31.7% identity in 382 aa overlap. Contains a
                     Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA
                     dehydrogenase and contains possible membrane spanning
                     hydrophobic domains."
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="NP_631004.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.2e-20, bitscore:
                     73.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 8.9e-18, bitscore:
                     63.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.2e-34, bitscore:
                     117.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATPTTPPPALRPYLTARHDMLWQEADAFATEHVAPRVARMEAA
                     PGRAESKIADLMAARGWFAVTVPAVFGGLGAGHVARTVLVHRIARVSAAAAAILQATLI
                     PVGAVLHFATYEQKGRWLPRVADGSLLPSIAVTEPLAGGHIGGIETTAERTGNEWVITG
                     SKIHIGNSHLAGAHLIVARTAAAGGSTSQALTAFMVEADRPGLSVPDHRAGLGLHGFSV
                     GRLDLDHVRVPEDNVVGEIGQGLAVAQSSSILYGRPNLAAVSLGVHEAVVDTTTARLKA
                     RPRYQGALSALPVLRDRVGDMEARLRAARILAYQAVHLLDQGLPCDAELINSKYLGHRW
                     AMQSAQDAMELHGAHALDRDYVLQRLWRDIQYTYPPAGTGEVQRIRLADAAFGEDHIQW
                     SERLAAEAAWARPDPTAA"
     PFAM_domain     complement(19809..20258)
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00441.27"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6938_0953"
                     /evalue="5.50E-34"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO6938"
                     /locus_tag="SCO6938"
                     /protein_end="391"
                     /protein_start="241"
                     /score="117.7"
                     /tool="antismash"
                     /translation="GQGLAVAQSSSILYGRPNLAAVSLGVHEAVVDTTTARLKARPRYQ
                     GALSALPVLRDRVGDMEARLRAARILAYQAVHLLDQGLPCDAELINSKYLGHRWAMQSA
                     QDAMELHGAHALDRDYVLQRLWRDIQYTYPPAGTGEVQRIRLADAA"
     misc_feature    complement(19815..20936)
                     /gene_synonym="SC1G8.10c"
                     /locus_tag="SCO6938"
                     /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA
                     dehydrogenase, score 142.40, E-value 6.2e-41"
     PFAM_domain     complement(20292..20585)
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02770.22"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6938_0952"
                     /evalue="1.60E-17"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO6938"
                     /locus_tag="SCO6938"
                     /protein_end="230"
                     /protein_start="132"
                     /score="63.6"
                     /tool="antismash"
                     /translation="SIAVTEPLAGGHIGGIETTAERTGNEWVITGSKIHIGNSHLAGAH
                     LIVARTAAAGGSTSQALTAFMVEADRPGLSVPDHRAGLGLHGFSVGRLDLDHV"
     PFAM_domain     complement(20598..20930)
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02771.19"
                     /db_xref="GO:0016627"
                     /db_xref="GO:0050660"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6938_0951"
                     /evalue="3.60E-20"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /gene_ontologies="GO:0050660: flavin adenine dinucleotide
                     binding"
                     /label="SCO6938"
                     /locus_tag="SCO6938"
                     /protein_end="128"
                     /protein_start="17"
                     /score="72.8"
                     /tool="antismash"
                     /translation="ARHDMLWQEADAFATEHVAPRVARMEAAPGRAESKIADLMAARGW
                     FAVTVPAVFGGLGAGHVARTVLVHRIARVSAAAAAILQATLIPVGAVLHFATYEQKGRW
                     LPRVADG"
     gene            complement(21064..21705)
                     /db_xref="GeneID:1102377"
                     /gene_synonym="SC1G8.11c"
                     /locus_tag="SCO6939"
     CDS             complement(21064..21705)
                     /codon_start=1
                     /db_xref="GeneID:1102377"
                     /gene_synonym="SC1G8.11c"
                     /locus_tag="SCO6939"
                     /note="SC1G8.11c, unknown, len: 213 aa. Similar to
                     Streptomyces coelicolor TR:CAB71245(EMBL:AL138598)
                     hypothetical 20.6 kd protein, SC1A2.07 (191 aa), fasta
                     scores opt: 376 z-score: 435.5 E(): 8.6e-17 43.9% identity
                     in 164 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_631005.1"
                     /transl_table=11
                     /translation="MSQHPSDPYRTPQTAPPARSLPRRDMRDTTRGPLTPPGTVLSSKP
                     PQQSLELAQRYELLNRLGVPPMANEDFDDLARDMATRARFQYGFVNLFLEEQTFVGLHQ
                     PPADSGYVFVGRTMSRDHGWCPEVMARKKALPLHDVHASPRFSGNAVVDAVGIRSYFGA
                     PLIHDSGTVLGTVCVIDPEKRPLAEARRLRDIVINASAQVMDHITRAPVR"
     PFAM_domain     complement(21151..21453)
                     /aSDomain="GAF"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01590.29"
                     /db_xref="GO:0005515"
                     /description="GAF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6939_0954"
                     /evalue="3.40E-08"
                     /gene_ontologies="GO:0005515: protein binding"
                     /label="SCO6939"
                     /locus_tag="SCO6939"
                     /protein_end="185"
                     /protein_start="84"
                     /score="34.3"
                     /tool="antismash"
                     /translation="FQYGFVNLFLEEQTFVGLHQPPADSGYVFVGRTMSRDHGWCPEVM
                     ARKKALPLHDVHASPRFSGNAVVDAVGIRSYFGAPLIHDSGTVLGTVCVIDPEKRP"
     gene            complement(21705..22283)
                     /db_xref="GeneID:1102378"
                     /gene_synonym="cvnD8; SC1G8.12c"
                     /locus_tag="SCO6940"
     CDS             complement(21705..22283)
                     /codon_start=1
                     /db_xref="GeneID:1102378"
                     /gene_synonym="cvnD8; SC1G8.12c"
                     /locus_tag="SCO6940"
                     /note="SC1G8.12c, cvnD8, possible ATP/GTP binding protein,
                     len: 192 aa. Highly similar to many Streptomyces coelicolor
                     ATP/GTP binding proteins including:
                     TR:CAB71244(EMBL:AL138598) SC1A2.06 (184 aa), fasta scores
                     opt: 630 z-score: 788.4 E(): 0 56.6% identity in 182 aa
                     overlap and TR:Q9X833(EMBL:AL049727) SC9B1.13C (181 aa),
                     fasta scores opt: 627 z-score: 784.8 E(): 0 58.0% identity
                     in 176 aa overlap. Contains a Prosite hit to PS00017
                     ATP/GTP-binding site motif A (P-loop)."
                     /product="ATP/GTP binding protein"
                     /protein_id="NP_631006.1"
                     /transl_table=11
                     /translation="MIAGGFGAGKTTAVGAVSEITPLSTEEYLTEASADVDSLAGLASK
                     RTTTVAFDFGRLSLPDAPMPLELFLFGTPGQDRFVDLWYDLSRGAVGAVVLVDTRRLES
                     SFTPVSFFEDIGLPFVVAVNRFDGAHRYHPEQVRAALELPAAVPVVTCDAREPNHVAGV
                     LLALVDHAVNCAATTNRAGHTPSTTLQDA"
     regulatory      complement(21712..21715)
                     /gene_synonym="cvnD8; SC1G8.12c"
                     /locus_tag="SCO6940"
                     /regulatory_class="ribosome_binding_site"
     PFAM_domain     complement(21765..22280)
                     /aSDomain="ATP_bind_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03029.20"
                     /description="Conserved hypothetical ATP binding protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6940_0955"
                     /evalue="8.90E-30"
                     /label="SCO6940"
                     /locus_tag="SCO6940"
                     /protein_end="173"
                     /protein_start="1"
                     /score="104.4"
                     /tool="antismash"
                     /translation="IAGGFGAGKTTAVGAVSEITPLSTEEYLTEASADVDSLAGLASKR
                     TTTVAFDFGRLSLPDAPMPLELFLFGTPGQDRFVDLWYDLSRGAVGAVVLVDTRRLESS
                     FTPVSFFEDIGLPFVVAVNRFDGAHRYHPEQVRAALELPAAVPVVTCDAREPNHVAGVL
                     LALVDHAVN"
     misc_feature    complement(22251..22274)
                     /gene_synonym="cvnD8; SC1G8.12c"
                     /locus_tag="SCO6940"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     gene            complement(22339..22746)
                     /db_xref="GeneID:1102379"
                     /gene_synonym="cvnC8; SC1G8.13c"
                     /locus_tag="SCO6941"
     CDS             complement(22339..22746)
                     /codon_start=1
                     /db_xref="GeneID:1102379"
                     /gene_synonym="cvnC8; SC1G8.13c"
                     /locus_tag="SCO6941"
                     /note="SC1G8.13c, cvnC8, unknown, len: 135 aa. Similar to
                     many proteins of undefined function from Streptomyces
                     coelicolor including: TR:O86520 (EMBL:AL031124) SC1C2.19C
                     (132 aa), fasta scores opt: 204 z-score: 259.5 E(): 5.4e-07
                     35.6% identity in 118 aa overlap and TR:Q9X834
                     (EMBL:AL049727) SC9B1.14C (119 aa), fasta scores opt: 137
                     z-score: 181.4 E(): 0.012 42.2% identity in 90 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_631007.1"
                     /transl_table=11
                     /translation="MSTYGRAAEESAFVRTSAVTRGRTKPRHLLALETVLEAGRGRPGP
                     AQAEECGEILALCRERRRSVVELAGRLGRPVTAVKVLVSDLLDADALVVPLTQSYADTG
                     AGSGPSIQMLAAVSVGLKRKWPDAVAYPQAG"
     PFAM_domain     complement(22375..22722)
                     /aSDomain="DUF742"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05331.14"
                     /description="Protein of unknown function (DUF742)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6941_0956"
                     /evalue="3.50E-33"
                     /label="SCO6941"
                     /locus_tag="SCO6941"
                     /protein_end="124"
                     /protein_start="8"
                     /score="114.0"
                     /tool="antismash"
                     /translation="EESAFVRTSAVTRGRTKPRHLLALETVLEAGRGRPGPAQAEECGE
                     ILALCRERRRSVVELAGRLGRPVTAVKVLVSDLLDADALVVPLTQSYADTGAGSGPSIQ
                     MLAAVSVGLKRK"
     gene            complement(22743..23258)
                     /db_xref="GeneID:1102380"
                     /gene_synonym="cvnB8; SC1G8.14c"
                     /locus_tag="SCO6942"
     CDS             complement(22743..23258)
                     /codon_start=1
                     /db_xref="GeneID:1102380"
                     /gene_synonym="cvnB8; SC1G8.14c"
                     /locus_tag="SCO6942"
                     /note="SC1G8.14c, cvnB8, unknown, len: 171 aa. Similar to
                     many proteins of undefined function from Streptomyces
                     coelicolor including: TR:CAB61281(EMBL:AL132991) SCF55.11C
                     (152 aa), fasta scores opt: 158 z-score: 212.6 E(): 0.00022
                     33.1% identity in 160 aa overlap and
                     TR:O86521(EMBL:AL031124) SC1C2.20C (140 aa), fasta scores
                     opt: 177 z-score: 237.3 E(): 9.4e-06 29.4% identity in 143
                     aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_631008.1"
                     /transl_table=11
                     /translation="MSTHPAMNNMTGDMPASATTTSGQRDSMVWLLRQFASETLGVTHA
                     VLLSRDGLRLLDSDVDKDWADELSAAFSGVASLSANITGPRGKKRPAGQVIIERDDCLF
                     FVQSAGRSAAFDNHPGNERGEVDTILAVIAARDADVGTVGFEMGRLVQKFAPYMVIPVR
                     VGTGGEVR"
     regulatory      complement(22750..22754)
                     /gene_synonym="cvnB8; SC1G8.14c"
                     /locus_tag="SCO6942"
                     /regulatory_class="ribosome_binding_site"
     PFAM_domain     complement(22923..23177)
                     /aSDomain="Robl_LC7"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03259.20"
                     /description="Roadblock/LC7 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6942_0957"
                     /evalue="1.40E-07"
                     /label="SCO6942"
                     /locus_tag="SCO6942"
                     /protein_end="112"
                     /protein_start="27"
                     /score="31.3"
                     /tool="antismash"
                     /translation="MVWLLRQFASETLGVTHAVLLSRDGLRLLDSDVDKDWADELSAAF
                     SGVASLSANITGPRGKKRPAGQVIIERDDCLFFVQSAGRS"
     regulatory      complement(23267..23270)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(23320..24837)
                     /db_xref="GeneID:1102381"
                     /gene_synonym="cvnA8; SC1G8.15c"
                     /locus_tag="SCO6943"
     CDS             complement(23320..24837)
                     /codon_start=1
                     /db_xref="GeneID:1102381"
                     /gene_synonym="cvnA8; SC1G8.15c"
                     /locus_tag="SCO6943"
                     /note="SC1G8.15c, cvnA8, possible sensor histidine-kinase,
                     len: 505 aa. Highly similar to many proteins from
                     Streptomyces coelicolor including: TR:CAB71241
                     (EMBL:AL138598) membrane protein, SC1A2.03 (650 aa), fasta
                     scores opt: 700 z-score: 669.8 E(): 7.6e-30 34.2% identity
                     in 524 aa overlap and TR:CAB76341 (EMBL:AL158061) sensor
                     histidine-kinase, SC6D11.18C (543 aa), fasta scores opt:
                     433 z-score: 417.8 E(): 8.3e-16 28.6% identity in 482 aa
                     overlap. Contains a Prosite hit to PS00017 ATP/GTP-binding
                     site motif A (P-loop) and a Pfam match to entry PF00512
                     signal, Histidine kinase. Also contains possible membrane
                     spanning hydrophobic domains."
                     /product="sensor histidine-kinase"
                     /protein_id="NP_631009.1"
                     /transl_table=11
                     /translation="MSDSAFPARPAATGHRRRRPPGDANMLLLARRAVTLPLVLLAALL
                     LAAVVLWSVSVVGPGWVLAGLICGLSGVAAVAAHGTRTVAGAVHSAVEESQAAALTAVA
                     GAAAAVGKSVQWSADELCRGKRPALPDPHTAQSPTPNAEIDNALSALQAQAIMSLIRVH
                     DESQSVVLLEVLRRLAMREHALVSKALEALSQLEMLTDDPELLAKIFEIDHLVTRMRRQ
                     VESTAVLGGQSLRSVRRPVPVTTALRGAVSEVVQYPRVAVAAGSVGAELGLPGHVGPDL
                     THLLAELIENACECSDPETRVMVRAQRVPHGLAIEVEDRAIPMHPQTRAQMNHLLKAPH
                     EVDVSGQVRAGQLGLLVAAKIAQSHGLSVLLQENATGGTTVLVVIPARLLVAIPSVEDA
                     GAPPPEGAGTSGRQPQQVAAAPAASGAHQAARPGATGAPTAEAGQSADAPALPTRTRRT
                     EPFRPPHEREQAPVAAATPGLAAAFRNGLQAGGTADCPPAPAEHPTP"
     PFAM_domain     complement(23677..24003)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02518.29"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6943_0958"
                     /evalue="5.70E-07"
                     /label="SCO6943"
                     /locus_tag="SCO6943"
                     /protein_end="387"
                     /protein_start="278"
                     /score="30.1"
                     /tool="antismash"
                     /translation="PDLTHLLAELIENACECSDPETRVMVRAQRVPHGLAIEVEDRAIP
                     MHPQTRAQMNHLLKAPHEVDVSGQVRAGQLGLLVAAKIAQSHGLSVLLQENATGGTTVL
                     VVIPA"
     misc_feature    complement(23680..24291)
                     /gene_synonym="cvnA8; SC1G8.15c"
                     /locus_tag="SCO6943"
                     /note="Pfam match to entry PF00512 signal, Histidine
                     kinase, score -32.90, E-value 0.0029"
     misc_feature    complement(24499..24522)
                     /gene_synonym="cvnA8; SC1G8.15c"
                     /locus_tag="SCO6943"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     regulatory      complement(24844..24847)
                     /regulatory_class="ribosome_binding_site"
ORIGIN
        1 ggatcctggg gatcatggag gtgatgaggt cctagtcctg gtggaggagc cggtcggtgg
       61 cgcgctggac acgctggacc gcgcggtccg tggccgcgat gaccacgtcg agttcgtccg
      121 ggcgtgcacc ggcgttgacc gctcgggcaa gctggttcaa gttgttgccg atgtggccga
      181 ggtgccgacg ggcggcgaag aactcggcga tcacctcacg ctcgtccgca acggcacttg
      241 cggtccgctc aaggtcacgg gcggcagaca gagcagcacg ggcgaggaag ccggcgaggg
      301 tgaggccggc agcctgcgcg ccggcggtca cgagatggag ttcgtcatca ctgaagcggg
      361 tgttgcggac gtgcggacgc tggcggcgct ggtacgtgcg gcgacgcgta cgcggctgct
      421 caggtttgtc ctgtgtccct gctggctgcg atccgccctc ggtcgcagcc tcctcgtccg
      481 gcgtcccccg gcgccggacg agccccggcc ctccagtggc gggggagccc ttggatactc
      541 cgctcaaggc ggagtatcca aggggataac ttgctcgccc cgagaccgag ttggagccgg
      601 gatcaggttc cggggtggtg ccgttcttgg gcgcgttcgt catcgggatt cggacctcgt
      661 agagcgggtg cgttgctgga tggttgcggc cagcgcgagg acatcggcgg ggctggcaag
      721 gacgcggacc ggtccgttgg gacggtcctg gacgagccac tgcccggtcg gcgtgaggac
      781 gacggcgtgg aggagctgcc ggcggaccag gacgtccgcc caggcatcgg catcggcggt
      841 ggtgggctgg gaagagcgag ggggatgcgg ggtcacggcg tacctcctaa caggggcggt
      901 ggcccggcgt ggaaccgggc cgcctttacg ggtacgagct ttgagctggg gctttgccga
      961 gttcagccgc actcggggca gcgcccgacg tgactgttga gcgcgcgggc catccgctgt
     1021 ttcgccgagg cagcttgctt cgcactggac ttcgccgccg gcctgcccgc atgccgctcg
     1081 gagtgagcaa gcatgaatcc gatctcgcgc tcgtactccg cccggacgat cttgaactgg
     1141 tggcaggtct tcatcgggcg gtgctcctcg tcgtcgtgac gtccccgttc cgcagctcct
     1201 gaaggacgag gccgagtcgg tcgttaccga cacccgtcag gccctggcgc cggatgattt
     1261 cgcgcagctg cacccgggtg atcgctccgt tgccgtcccg ttcgagcagg gcgggtacat
     1321 gggggcgcac ctcgcggaca agctggcgct cggactcacc cagctcgcgt gcctggcgct
     1381 ccgtctgcgg agagcgggac cgggcacgct tgcccttgtt cttcgtccgg gacggcctgg
     1441 gcggcttccg ccggagcggg accttgcgtc cttggtcctg ggtggtgtcg gtcccggact
     1501 gtggggtggt cggtccttgg tcctgggtgg tgtcggtccc ggactgtggg gtggtcggtc
     1561 cttggtcctg ggtggtgtcg gtcccggact gtggggtggt cggtccttgg tcctgggtgg
     1621 tgtcggtccc ggactgtggg gtggtcggtc ctcggtcctc ggtgctctcg gtcccggact
     1681 ttgcggtgcc cggacccgga tgagaatccg tgccctgagc cgctacttct cgcgcgttgt
     1741 ggtcggtcct catggccgct gcgtcccgcg ctgcggcttc aggaccggcg ggctcggtcc
     1801 ccgggaccgc accgtcttca cggggcttgg tcccagcggc cgttcccgtt gcgtcgccct
     1861 cggtccccgc gccgaccgtg gcttccgggt ccgtctcctc ggggcccggt ccccgaggag
     1921 tcctcggtcc tcggtcccgg accggctcgt cggaaccgtc gtgaccgggg gcggggaccg
     1981 gctcattcga tggcggctgt gcggggaccg tggccgccga tgcgctgctg tgggctgggg
     2041 accagggaga agggagctgg accgtggcga gcgcgagtgc gtgtcgtcgg gcggcgagct
     2101 ggtcgagtag ctgtgcccgc tggagggggt cggtgccgac cgaggccctg ccgactgcct
     2161 tcgacaggcg tcgcgtcagc cgccggccgc gacggctctg ctgctgctcg ggtgtgcgct
     2221 cggcgaggcg ggcggcgagg gtgaccgcgc gggtggtggc ccggtcccgg gtgatctggg
     2281 cggcgtcgcg gtctcgcgcg gcaatgccca ggcgggacag gagccgctcg cgtgcctccc
     2341 ggcctaggac ggcgatcagt ccatgcgagg cggcgccggg ggtgcgtagg cgcagttcaa
     2401 tgcccatggc caggtgccac agcatcgccg ccatgaccgg tccgacgaag gcgcggaccg
     2461 tgccgccgac ggggccgctc tcggcgtagg cggggatcac ctgcaccgtg gtgatcaccc
     2521 agaccagcgt gcccggcagg ccgggagcgc cttggacggc gaggttctgc cgcgccatca
     2581 gcgcggtcgc aaagagcgcc atctcggcag cggcgaacat cgcggcgcgc tcggcggtgc
     2641 cggccatgtc gaggtagtcg gcggcgaact gccagctggt gtcggcgctg taggcggtgc
     2701 agcccagggc ggcgacggcg gcgaccttga ccgctggccc gccgtcacgt ttctgcggac
     2761 gggctctccc gcgccggaca gtccaggcgg tcagcacgag cgcgaggacg gcgggcacga
     2821 tggcggccag gagaaggggg aggcccgagg tggcaccgaa ggcgaggacg gggtgggtca
     2881 tgctgccttt ccgagagggg cctgcgccgg tggcgaggct gcagggcggc ctgcgggctg
     2941 ctgggtgccg ggggctgcgg gcgtgggggt gccctcggcc ttggagggct tcttccgctt
     3001 cttcttccgg cggggcacgc cgtaggtgcg gtcgcggtcg aagaccttgt tggccgcttg
     3061 ccggagcagg tcgcgagcgt gcttgtggct gatctgcagg gcggcggcga gccggtccgg
     3121 ctgccagccc cggacgtagg cgtggtcgat gacgacctgc cgctcggcct cggtcaggtg
     3181 cacgtcgcgt ccatagaaga gggcggttac gcgccggtag tccaggcgct ggtgcaggtt
     3241 gtcgtgcagc gggcggcgct ctgcttcagt gagcccgccc cagacgccct ctttgaggac
     3301 gttctccagg gcgaagtcca ggcacgcgcg gcggacgggg caccagccgc acagctcctt
     3361 cgcctccgcg atctcttcgt gatcccgggg cccggggaag aacacggcgt cggcgtcctc
     3421 gatgtccatg ccgtggcacg ctccgcggac gtgccagctg gtgtctgcga tgctgcgcag
     3481 gccggtggcc ggcgcgtcgt gggtggtgat gtggcgcaag gcgggtctcc gatgtgctgc
     3541 cgcaccggtc gggctagggc ggtgctcggc gggtgcggcg tcggggccgg cctgggcgca
     3601 gggcgtgcgc tgcagccggt gcgggacggt gatggtgtgg cggtgcagcg gacgggatgc
     3661 acgggccaca gggcgccggt caggccaggg cgggctgctg ggccttctcg gtgcgctggg
     3721 cctgcttggc ggcggcgagg tcgaggcggc cgggatgggg gtcggtgcgc ggcgtgatgg
     3781 tgcgcactct gtcgttgggg ccgatccgtc ggcgccggca tggctcgccg accggggcca
     3841 gacaccactc acatcgcacg ctcagggcat cgggcagccc ctgcgcgacg gcggcttcgc
     3901 gtgctgcccg ggcgggccgg aacggtgcga gggctgcccg ggcagcggga ggtatgcagg
     3961 agccgatctc gttcagccga gcctgcagcc tcgggttgag ctcttcctgg ctgctggtga
     4021 tggctggggc atacgcgggc tgtgctgtgc cggcggcgac ggcgcggcgg gtgccgacca
     4081 gctctgcggt ccaggcggcc tggtcgtccg ggtccgcgga cggtgtgggg tcccagtgga
     4141 gggccaggcg gttgcgccgg tagctctccc aggggcggac cacgtccgcg ggctggatct
     4201 ggtacggcga ggtgcggtag tgctggcggg cagcgacgcg ggcgtcccag ccgtgcgagg
     4261 tggccatcgg cacatcaccg agcagctcgt gccactgcgc gagctgatcg cgggcctcgc
     4321 cctcgtcggt gcggatgctg cgagggtcga gccggccgat gtaggccagc agggcggcga
     4381 tttcgcggcg gtccacgctc agccctccgt tccggtcggc tcgtccaggg cggcgagaag
     4441 ggcggcggtg tgcttctcgg cccgcgtcat cccgctcgac gaggtggtgt tcttgccggg
     4501 cacggcgtag aggttcgggc ggttgggggc gtgctcccga gtgatccagg agcgccagtc
     4561 ggcagcccag gcttccgccg gcctcggcgc atggcccgcc cggtgggccc gccacttcgc
     4621 gtcggcggcg tgcaggccct gcgcgccgag gcggtcgagg tgtccctgct ggcgggccca
     4681 ggtgtgggtg gcggggtcga cctgccactc ggtagccgag gtgaccgcag caccactact
     4741 gctgtacctc cggttcaaat taggttcact acggttctgt gtgccggtag ccggtacatc
     4801 cctgtgccgg tttccggcac gtcggggtgc cggtttacgc cttgacctgc cggtttccgg
     4861 tactgccggt ttccggaccc tggcagggga ttccggcacc tcacgctggc ggatcccgta
     4921 ccgccgcagg accgagagcc ggagcgcggc gggggcggcc ggctcgtccg ccaccgccgt
     4981 agcaccgtct gcctcctgct gctgtcgcag cgcctgcgcg acggcttcgg cggcgagagg
     5041 caggcggtag acggtgctgc gctgcgggcc caccaggtcg tcgagctgct ccagttcgcc
     5101 ggccaggagc agacgtccga tggcctcgcg caccgtggag accgaggcgc gggtgcgctt
     5161 ggccaggctg gacagcgagg cccaggagac gcactgctcg tcggccactc ggtcggcgat
     5221 cgacagcagg accagacgcg cagcccctcg gctggaactg tgctcccaca cccagtcacg
     5281 ggcttcgctg ctcatcggcc acccccgacg agcgcgcggg gccgtcggct cggctcggag
     5341 cgctgaggcg gcgaggcaag ggtggctgcc gcgcaggcca ggcggaaggg ccttatgcgc
     5401 agggcaggag acatgcgata ctcccttttg cagtgttgcc acgttgatgc gcccgtcgga
     5461 aggactcagc gtggtgatgg cgggcagtcg ccgcccttgc cggggcggtc atgccgctta
     5521 gccttcggcg tccgggagtt accgctctcg ggcgccgtcg ctggttcatg gaccttcggg
     5581 gtccggttcg tgctctcctc acgttcgttg ccgtgggcgg gctgcccagg gacgacgaac
     5641 atacgcacgg acccgtgtca aggtccagac ttggttctta aactctgtac tagttgcaga
     5701 tagtcatcga atgatcgcgc tcccgttcca gggagtggcc gttaggccga cgaagctcgg
     5761 tccggctctg ggggcggggg cggctgccgc gccgaccggg tgcgccatcc cgttgcctgg
     5821 gcgggcacgt gggcgtacct cccggtgaag ccgcgcttat acgcctggag gagagagggc
     5881 cggcgcggga agggcggtga gaatgtctcc ccagatgtgg gctgaccatt tagcgtccgc
     5941 cggccgggag ttgaatcatc ccttgagcgt cgcagctgat aatgcggccc tccgtcagcc
     6001 caggaatttg cgccctccgc gtaacactcg tcttgtcaag ggtcgggcta gacaccggtc
     6061 cgaggatggc gaacatatgc ggtaaatacg ccaagatcca gaacttgctg aagtactctc
     6121 tgtcgaacga cggggccccc aatacgtggc tctctcggtg gaggcagcaa acagagaggc
     6181 gggcggcggc tcgactgccc cgacgttctt gcagatgatc ttcactgcac cctccctcct
     6241 gtcgcgtgct gcagcggctt gctcgaccgc ccgatcagag tgatccacgt catgtctgac
     6301 cagtagcgct cgctgatcca gtgagggcat ggcttatacc cccgcgactc accccgtgac
     6361 ctgcggtgcg ctgtatggac gaacagatct tgggcttggt ccggatcatt cgtcaatgcg
     6421 cggtaaagat cacagcgggg tcacgggagg tctgctacgg aaatgctcgt tgcgtcccaa
     6481 cgctgttcaa cttgcctgta tatacgcgta cttcgctatc cctgggtggc gcggctatca
     6541 atggctctct gtgccctcag gggacaagtc ggtcaaaatg cggtgaccgg caatcttctg
     6601 ccggtcgcgc agtgccgcca tcgctctatc atgtagcgca gggggcggcg tctgctcgat
     6661 atagccttga gaaacgcgcg atttgatcag gaccaggcag acgagaagtg cgaggaacgt
     6721 ggcatgtgcg gggccataaa ggatggcggc ggtgaaggag aatccaccgg gatcggcgcc
     6781 ctgctgcgtg tcttccgggc cgctgccggc accacgctcg gccgcccgat cctccagaga
     6841 gaagtggccg acgccctgca caggagcgag cgctggtacc gggacctcga aggcggagtg
     6901 atcacccggc ccctcacccg ccacgaactc gacaccatcg gcacgctact cggactcgac
     6961 cgcgtccaga gacgtgcgct gttcctcgtc agcaacggcg ggggactctc cagcccggaa
     7021 acccaggaac caccacgcat cagcgacgaa ctgcgcctcc tgctggacca gcagcctttc
     7081 cccgcctacg tcatcgatgc cacctggaac gtcttggccg tcaacacttc gatggccgct
     7141 ctgttcccgt ggtcgaccgc tcccggggcc aacctcatgc ggtggctgct cctcagcgcc
     7201 gaagcgcggg accagcatct gcactgggag gccgacgcgg aggtgtgcgt gtgcatgctc
     7261 cgcgacgcgg ccgtcgaccg cccccacgac ccagaccttc agcagctcat cagtgacagc
     7321 cgccagaacc ccgccgtacg cgacctgtgg acccgtggcg cagccgactt cgccgaccac
     7381 tatgacggcc acgtactgca gatgacgctt ccgctcttcg acggtcaagt gaccgaactg
     7441 gtcactcacg tgctgcaacc cgctggtctt cctggttgcc gcatgacgat cctgacccag
     7501 cgagcaccgc aggagccatc aggccggcaa cctgtccaag caacgtgacg ggccccctcc
     7561 ggactcggcc atccgcggcc tgccggggaa accctggcag gcggttcccg cgcagcccct
     7621 gccaaccggt tgccgggaca accgtggcga cgttccctcc gagcgacgac tggcgttcca
     7681 cgggacgctg ctctcagcca cccccgcacc agtccgtcct cggcgtgagc tgcgtgctcc
     7741 tagtggccga cgaacggcag gaagtcgacg ccgccaagat caacgaccac gagtgagacg
     7801 gcggacaggg ccgctaacgc cgccgcttgt tgtcggctcg ttcccgcggc aggctgtcgt
     7861 ttctcgaagc gtcgaggctg cacccggtcg aggcaaggct ctccattcgg tcccgttcgg
     7921 cagactgagg acccagatcc ggctggtacg gcatgaccga cccggatccg gcattcgcct
     7981 gtttgtccgc gtcagcaacg ctgtccgctc ctcttgcatt cgagggtgcc aactccagcg
     8041 gttccggcca gttgaactgt cccaaggccc atgcgccgca ttcaacttgc aggctcatac
     8101 cctgacttct atagaatccc gtcagagcga cagcaaacgc aagatcgcac accgttacag
     8161 aaatgggagc tgttgttacg ggccggcgag agcagcaatg ctgcgtggta atcgtcaccc
     8221 ttcagtgaag ggaggaaggc catagaatgg ggcaatgatc atcaacgatg tgcgcggcgg
     8281 acaactcctc cgcgtaggag acccggggcg aggggttcac ctgctgttct ccacgccgac
     8341 acggccgtac ggggacgacc ctgcgctcga tatgaccgtg cgggccaagg gtgcgtgggt
     8401 ggacgtcagc gagttggtcc ggacgctgga cggtgacgga ctggtggaat tcatttcatc
     8461 actggctgac gcatcgggca gctggagtgg acctcgtact tggcagtcca gtgaggggca
     8521 actgaagata tcggcacagc gttcggatgg gggcatcgtc ctgacgtggg ggatatggcg
     8581 aggggcgacc gtgtccgaaa gtgcgtggta cttcgagact gtcacatcgc acagggctga
     8641 gggcgagatg cagggatttg cggaagcgct tcgggctcta tttgacggga cctcagaagc
     8701 ggttgcctag atggctaccg ggcgccccag gtgtgctgcc cctggaaggg cccgcagcgg
     8761 caagaccgct aggctggccc atcaacctcc tccctgccat cttgcgttct gacgcgttcc
     8821 ttcctccgtc aagggtgtga gggcgacgta acgccaaggg gctcgccgtc gcggtcaaga
     8881 gtcgaggttg cgcgacgagc cggggctagc tcgacgggtg acgtggcgct cccagacatc
     8941 cgccgaaacg gacgcagcac ccagcagggc ctgtgtcagg ggctcgggga tgtgcccctg
     9001 gccgaggccg gctgaggcga cggcggcgga aagcgtacgg tgctcgccgt ggcccagcgc
     9061 ttcgcggcac acagggtggg ccaggacgtc ccgtgcgacg tacccgtctg tctgcctcat
     9121 cgcttcgcag gtgagacggc gcattgcttc ggcctgtcgg gtcttcgggg agaggtcgag
     9181 cacgactagt cccacacggg agcggaagac ggcaagttcg ggagccgagt cgagggccaa
     9241 gtagtgctgc accatcttgt cgaccggctc gaccgggtgc tcgtcggctg ccctgtggca
     9301 gaggacggtg agcgctgccg cgacggattg ctcccatggc tccaccagtt ggctcgtgtg
     9361 caggaacatc agcgcatcgc tgggctgctc gccgaggcag cggacgagca cttccacttg
     9421 acgcccgtcg aagaggcgct ggcctatgcc ccgatgctgc ctgctgtgcg cccgtgcgcg
     9481 gtcccattcg cccgctgcga cgagggcgcg ggttccgtcg ccgaggagga cggtccacag
     9541 ccattggcac acctgttgat ggtcggctgc cgacgtcgtg aggtgctgca acggcgtggt
     9601 gcggccgtcg atgaccgctt ccgtcttcga tctgactgct ctgttcaggg agtcgagcag
     9661 gtggtatgcg ccgtgcccgt cgccgtcgcg gatgcgcaac cgggccaggt tgaccagtgg
     9721 ttccagggcg taccgggctt cctgcgcgcc caggggttgg gcacgcagga cggcctcggc
     9781 gtgacgccag cacagagtgc gcgccaggtc cggcatgccg cagtcgctcg cgatcagcgc
     9841 cgccttgttc agggcgacgg tcgcggaggt cacgttgccg tcgcgctcgg cggcggctgc
     9901 aaggtcggtg atctcgcgga ctcgttcagc gaggggcagg cacgctggac gtggacgggc
     9961 aacgagcggg aaccgcttcg ctatctggcc gacgtccatg tcactgccat tcgatgacga
    10021 tgcggttcag cgggttgtcg aaggcgaagc ggccgggctt cggcgcgagc ggggccgcgt
    10081 cgagcggctg aatctcgaag ccaacgtcga gcgctcggaa gtcctggtcc caggcgcgga
    10141 tctggtccgc gacgtccccg gcgagggcct cggcgtcggg gccgtggccg atgacaccga
    10201 actcgtacag ggtggcgccg tcgggggcct tcttcgcgta cgggcgccgg gtgaggtagg
    10261 tgagggtgcc gtcctcgaag accgcggtcg aggacgggta gggcgcggtg accagcccct
    10321 tctcgatggc ctcgttcttg gcgggcatcc ggctcaggcc gttgggcatg gcgcaggtga
    10381 gccacagctc caggtactcc gccgactccg ggccgcggaa ggtgacgtcc gtccacgcct
    10441 cggtgcgcgg ctggcggaag atgtcgccga gggcgtccgc gtcgaccttc tggtctccgt
    10501 tggtgacgag ggtgacggtg tggtcggggt ccaggggtac gaagaggcgc gggtcgtcgg
    10561 cgatgccccg gcgcagaggc atgaacgtgt tcatctgact gccgacgctg cgccaggctc
    10621 cgtcctggtt ctcaaaggcg atcgagcggg agacgctgcc gcgcaggcgc agcggggtga
    10681 ggagccgtcc gccaggggcg agctggtcga gccaggcgtg cgggacgccg tgggcgccga
    10741 cggtggcttc gatgcggtcg tacggcgcgt tgggggtgtg gccgactgct ccgtctccga
    10801 ggatcacctc cacgttgtgg atgccggcgg cggccaggcc gccgcgcgct ccggccacga
    10861 tgtcctcgtc cacgtcgatc gtagtgacgt gtcccgtctc gccgacgagg tagcccagga
    10921 gtccggcgtt gaagccggtg cctgccccca gctccaggat cttctggccg ggctggacgt
    10981 cgagctgttc cagcatcatg gcgacgatgt cgggctgtga ggcgcagctg atggagcgcc
    11041 cggatccgtc gaacttcgtg tccacgggcg cgttgccgta cgccttctcc aggggcgcgt
    11101 tcgggacgaa gaggtgacgg ggcacggtcc gcatggcctc ctccacccgg ggggtgcgca
    11161 cgcacccggt ctcgaccagg tggtcgatca actgggcgcg cagacggtcg gcggaagggg
    11221 cttcgatggt gtcactgttc accccgttga ccgtagcgcc cggtgccccc tcagcttggg
    11281 tggacgcggc gttgtcgctc gttcccatga ctacctcttt cgcgagtgtt gacaaggtgt
    11341 gctggtcctg ggcggcaagg cccaggcggt tgaagtggaa gatgccgtgg tgggcgatca
    11401 cggcccgcag ccctcgttcc aggcggccct ggcggttgag gtcggcgagc tgctggccga
    11461 accactcgaa ggtggctatc cactcggcca gcggcgccag tcggccccgg gcgacgctgc
    11521 ggctggtggt gctgacgtcg acggtcatca accggtggac agcggcccgg tgccgttgcg
    11581 gactacggac ctcgtcgccg gagcgctcgg ccgcgatcct cgcccagacg tcgccctgct
    11641 cgtaccagtc gaggcccgcc gctcgcatcg ccacgctgag caggaggacc gccagctcgc
    11701 gccggccgag ccgggggccg ctcactgtct gctggcgggc cgcctcgtcc agcaggtgac
    11761 ggctgtcgta gtggaacagg gcgtgcgcaa tcttcatcgc ggcggggccg ccgaaggccg
    11821 tctcttccgg ttcgtagatg cctcgcgtcc aggaggcgag gacgccggcg tcgaccagct
    11881 cgtccagggc agcgtccagg gccttcgccg agtccgggca cgcgggccgg taccgcaacc
    11941 gccaccaggg gtgcttccgc aggaacgacc actgggccag ttccgactcc tgggcgatca
    12001 gcaccgggag tagatgctcc acggcggtgg cctccgcgtg actccagtcg gtgaaccgga
    12061 tgaggcgttg cggccattcg tccgcagtca tgttccctct tctcgtcgtc tagttggtca
    12121 gaaagcaggt ctcccacccg gacgcggacg gcgttccggt gtggaaggag tgcagggcga
    12181 gtgcggtgcc tgcggcacct tcgaggagcc cgatgtcgcc gccgctagga gggctgatca
    12241 gggagtccgc cagggtgccc ggcgcggtgt cggtgatcgg ggccaggagc cggggcaggc
    12301 atgcggtgag gccgggtgtg agggcgtcgt cggcagcgag gcgcgtgatg tgcgccaggc
    12361 ccgcgaagcc gtggcacagg gacatgtcca cggtcgcgtc gagttggccg gagtcggtca
    12421 tggcgcgcag gagggcgaac tcggcggcgt gttggcgcgc cggatccttg agggccaggg
    12481 cggcgagttg ttggacgcgg gcgaatccgg cggtgccgta gcaccaggac ggccgggagg
    12541 ggccgggccc ggtcgtgccg gatcgtagct gctcgcgggt gatccagtac ggccaccacg
    12601 gtccggcggg gccgtcctgc tgccagtggt cgagccaggt caggatgccg gtgatcgcgt
    12661 cgaggtggcc gtcgacggtg atgccgcggc gggccgcgag ggagagcacg gcgagggggc
    12721 cgccgatgcc gtgggcgacg ccgttgttgg cgtgcccttc cggatactcc ggggagatcg
    12781 tgccggaggg ggcgaggtgg ctccaccagc cgggcagaac ttccccgtcg tgcttgaccg
    12841 gctcggtcag gcggaccagg taggtcagga cctcgcggag gacgtcggtg tggacgtctc
    12901 ggtgcagcag gagcccgccc atcccgctca ggccgcggat cgcgtcgaac tcggccagcg
    12961 cgggcatctc accgcggtcc atccgtgcgt gggcgcccgc gagccggtcc cggatggcct
    13021 tcgtgacgta ccggtcgagg gtgtccaggg cgcgggcgta gcgtccgggg cggtcggcgg
    13081 cggcgtgcag ggcgaaggcg agcgcgggcg ccccgtagta gaggtggctg tccgggccgc
    13141 cgacggcggg ttcggctgcg gcgcaggcga gccagtcgtg ggcgcgctgc cacggcccct
    13201 ggtcggtgcg ggcccgctcg atgtgcagca gcgcgacacc ggctgcgccg tgtgcgagcg
    13261 actgcggcca ccagccctgg cggtgatgca gctcccgtat gtcctgtggt gaggcgagtc
    13321 gctcggcgat cgtgtcggcg gtggccagtg cgctgtcacg cagattcatg gtgatctcct
    13381 cggtgagtcc aggccatggc ggcggcgtgg gccagccgta cgcacatccg ctcgtcgtcc
    13441 ttgtcgatgc cggcggcgcg gatgtggtgg gcgtgcagga gcgagtcgag aacgaggtct
    13501 aggtctatgc ctccgaacgc gtccagcttc tgccggtagc gggccagggc cgcgtcgcgc
    13561 tcgctccagg cgctggcgat ggcgtcgcca ccgggggccg cgcgcagggc cgcccagccg
    13621 tcggccgggt cggctaggcg cagcgcctga ccgcgcacgg tccggtccat agggcgcggg
    13681 tcagtgatcc ggccgtgggc gatcagccag ttcatgccgg ctgcggtgct gccggtgaag
    13741 gcggcggcga cggagacgaa gttcgctgcg gcgaggacct gttggtgcgg acgggagctt
    13801 tgggcgaact ggacggccag ggctcgggag tcagcggcga agacgtcctc ggccaggttc
    13861 atcagcggcc cggggcccca ccggccagtt tccgggtacg aggtcgcgaa ctgcatgtcg
    13921 gcgaggagcc cggcacggcg caagccgttc gcccacgaac tcacgcgccg cgcggtgagg
    13981 gcgaagtcct gctcgctggg gaccgcgatg cgcagccgca ggtgccagcg agggtcgcgg
    14041 tagcgcatgt accaccaggt cggcggctcg tcccactggc cgagcagcgc gggaagatgg
    14101 tcggcaagga tctcgggctg ccggtcgacg tgcccgtaca gcttgaccag cagccaggag
    14161 gcggcgcccg gaaggtaacc gtggtcgcgg gtgacgagct ggtccgcggt gacgggaggg
    14221 acggccggcc actgcggcgg gcggacggcc gtcatcgggg cgatgatctc atgggaccgt
    14281 ccgtcgaacc agccttcctc ggattccgct tccgtcaaga tcaccgattc atgagtgtcc
    14341 aggtgggcgc gcagcagcgc gaggtgcgcg cgctcggaga ggtccagcgg cagaagctgg
    14401 tcgccctcgg ccaccgcgac ttcgtccgga actcggcggc gtgcgcgcca ctcgtcggcc
    14461 gccttgtgcc actcccccca ggaggcgcgg cggtcgggca gctccgaccg gtccagtcgc
    14521 cacctcgccg gagagaggat cgcgcggccg tagcgcaccc gcggcaggta cggcagtgcg
    14581 gtagcggacg cccaggggaa gacggtcagg acggcggtct gggcccggct gatctcggtg
    14641 aggaagcgtc cgagcggcgg cgtgtggccg cgcaggtcca gcgcgtgcag cgtcatgggg
    14701 tccagcaggc aggcgcggga gagggagacg aggtagagcc tgcggcggtc gcagcccacg
    14761 gcgaggtcgt cgagcgggat ggtgcgcgcg tcgaccggac ggtgctccgc caggctgatg
    14821 acggccggca ggagttctgt aacgcgggtg acgttggtgt cgccccggtc gagtggggtg
    14881 aaagagacct gcgtgggcac cgcgccgggc gtgttgaccg gcagctcctc cagcatgacg
    14941 gccacgcggg cctgttcgtc tggtgcgagc agccccaggc tgcggccgat cgtggtgccg
    15001 atcccgcggg acggggcgat gccgtgaaga acgaagtctc cactctccag agcctcttgt
    15061 gaagtggcac ggattcgaaa gcgcagctcc gtgtgggccg gtacatgcgg ggcgttgcga
    15121 tctccgaccg tcaacgtgcg gatcaggtcc tcgtccaggt ggatctcgtc gcggccgtcg
    15181 aggacggccg cttgggcgag ggagagcagc cgctgttcac gggcggtcag ggcctcaccc
    15241 tgttcaggtt gcgcatcgcg gtatccgacc gggaacccga ggccgacgtc cgggtccacc
    15301 aggtcccgga ccgggacgag tgagttgatg ccgtaccgct cgaagaatcg gttgtggaag
    15361 tccttccatg ccggagtgcc gaaggggtac gcgctcagcc gggccagcac cgtggcggcc
    15421 tgctccgcct cgcgggcaac ctgtgggggc agagtgaggg agcagtccat gcgaaggtcc
    15481 agcgtgaacg gctgagcctt gacgctactc aaggcggtca ttttccgacg taaggcggta
    15541 cgcaggcgcc ggccgtccgc cggggccagt acctggttgt gccgggcgat ggcgtcgcgg
    15601 accgtccgca ggtcggccac gaggcccgtg gctgatgggg cggcggctgc ttcggcctgc
    15661 tcgaccaggt ggtccagggc gtcgagggtg gcagagggcg cgtgcaggct gctgatgagc
    15721 acaccgcgtt cgacgaggct gctgacgagc ccttccaccc ggtccgcggg aacgtcgggg
    15781 aactcgctcc tcatcagtgc gaccaccgca tggacgggga cgggcgaggc ggcggcatca
    15841 acggcgatac gtacggcgct ggtgtaccgg acggacacct cggccgccgg gctgccgtcg
    15901 gtacggcatg aacggggcgg gtagggcatg atcagccgat cgccccgtat gaggatggtg
    15961 ttgttggcca tcacatgcag gtgccgcaga agttcaggat ctgcttccag acgggcgacc
    16021 aggtccgcga tccagtcgcc gtcggcacgg atgacgggtc gatgccactc accccaggac
    16081 catcccggtc gttccccgaa cgaggcgggc gcgataccgg cgaacagacc gttcggggtc
    16141 gcccggcccg tcatacgcag caggtaccgc atgaccgaca ccactgcgcg gcgcaactga
    16201 cgggtctcgg ggctggccac cgagcacagg gcctgaacct gctgcgcgag cagagggctg
    16261 gcctgctcga tggagtcggc ggcctcggaa agcgaccaga cgtcgcgcag ccacgtctgc
    16321 caccgcacct cacagtccgg ggtgtcgtcg gtgaggtccg gccacgcggg aagcggcagc
    16381 ctcgcggaac gggcggcgcg caccagcgca gtatccgcgc accggtacag cgggcagtcc
    16441 ttccgggaac ccatgcaccc tccctggttg tggtgtgttg gggtgggtgc cagcccgcgc
    16501 ggcgcaaggc cgcgcgggct ggcagatcaa tgcgccgagg tcaggccacg ttggtggcgc
    16561 acgggctgga gcaggtgctg ccgcagccgt cgtcggtgag gttgatcagc gtggcggagc
    16621 cgtcgtcgga ctccaggacg ctgatgtcca ggtcgaatgc gtcaccgccc gccgtggcgg
    16681 ccggggagtg tgcctggccc ttgatcgtgt tcgcgttcat gcggatttct ccctactcgt
    16741 cgtgcggtgg aagatgatca ggccacgttg gtggcgcacg ggctggagca ggtgctgccg
    16801 cagccgtcgt cggtgaggtt gatcagcgtg gcggagccgt cgtcggactc caggacgctg
    16861 atgtcgaggt cgaattcgtc gttctgcatg tggtgattcc tccgttgtcg tgcgcggctc
    16921 cgatcgagcc gcgagggacg tgccgcgtgg gcggcgccga caggacatgg gcgtcgtgcc
    16981 ggtggtctgg tgcggtcagg agccgctgga gatacaggcg ttgccaccgc aggttgagcc
    17041 gcaaccgccg tcggaggcga tactcgcccc gaccgtgcca cccgattcga tgacgctgat
    17101 gtcgaggtcg aacgggtcct gcgcggtaga ggccgaggcg gtcctcatgc cctggccggt
    17161 catcctggga gtcacgggaa tcctcctgat tggtccggtg gaacacttcg aatcggtgtg
    17221 ttgcgtacgg ccgactccgg tgggcggcag ctgtgtggcc tgcgctggcc tcctcttcag
    17281 acacgagaac tgctgtccgg aagaggagtt ggggacggga cacggaagtc cgaaaggtga
    17341 accgagatat gccgtcaggc tgccgcgggc tgcacttgag gttggttctt cgcggcctgg
    17401 tccagcaccc gggtgaagtg ctcggcccgc acgtctccct tggcctcctg agcgcggagg
    17461 tcgccgaagc gctgccagta gcgccggcag acgtcactgc tcatgaccgt ctcggagtag
    17521 aacggcagct gtccgtcgcg gacgcggccg aggcagtgtc ggacgctgag ggcgcagatg
    17581 agtcggttgg ccgacatgag ctgcatgtac tcctcggcct tcatgtcctc gggcttccac
    17641 agctcggcaa ggtcggcgtt ggtggacacc cggttcagcc agtcgagctg ggtgcccgcc
    17701 aggagcgcct cgtgccgctc ggcctggtgc cgtgcgttct gcctgagccg ggcggctccg
    17761 accacggcgg tcgtgaggga cagggcaaca ccggcagcga ggacggcggt agggagcttc
    17821 atcgatcaac aaccctttcg cagagcggat gtgcggcatg aaggccgaat ggtggggacc
    17881 gcggtgttcg gcttgttcac gcggcctccg cgaggacgac gctcgggact tcatcgctag
    17941 agccgttagg catgtaccgg cgacgcaccg tctccagtgc gacagcgatc ggcggcagac
    18001 cgaccgtgac ccttcgtttg tcgacggatc ccggcgcgcg cagtgggcac agctcgatgc
    18061 ggtcggagcg cagcaggagc tgggtgccgt actcctggtc ctggccggtg ttgatgaggg
    18121 tgcggtcgtg caggtgtgcc cagtggtgga cgagcgcatc gccgacctcg accgcacgcc
    18181 caagcaggat ggtggcggcg cgctggaaga cgagatcgtg gtcgctgtgc agggcgatac
    18241 tccaggcggc tcgggcagca gcagggccga cgaggcggtg gccgggccac tcgtattcgc
    18301 ccaggacgcg gcgcagaaac ttggcgttgg cgtagtcggt gtgccgacca cggccgagtt
    18361 ggacgccatc gagctggttg cgcacgcgtg tggcccggtg cgcggccgat tccgtggcgc
    18421 gggcgatcag ctcgcgggcg atgtcaggcc gctgcggcgt ttcggttgtc acgtgctgct
    18481 cccttcctcc gcggcaagat ggggagcttg ggcttggcag ctgatcagtg cgctgagtcc
    18541 ggggcggtgc tcggcggcca gttcgaggcg ggcgacccgg tccccctccc gtcccggacc
    18601 ggaaccccgc acgtcccagc ccatgtccgt gagccgacgc agcagggcgg cgatgggttc
    18661 ggcttgcagg gtgtggcccg ccgggatttc ggcccgtacg agcgggaggc tctgccgggc
    18721 ggcgaagtcg gaggcccaca gggtgatcag ccgggtgatg tcgtcgggct gctcgggcag
    18781 ggtgtggatg tggcccaggc ggaggcaggg gccttcgccc cagctgagtc cggggtcgcg
    18841 cgcggggacc atgcaggcga gcagctttcc gtcctcgaac agaccggccg acgtcgtgtg
    18901 gtgcgggtcg cggaacaggg ccggcacgtc ggcttgggcg ggcacgggca gaccgcgcag
    18961 ggtgagccag cgctgccggt cctgcacgag ggcagcggct tccgcgcgct cggcgtccgt
    19021 acgtaacctg cgcaccgcgt acacggcgcc cgggtacttc gctgcgaacg aggtggaagc
    19081 cggagccccc tcgttggcca ggaaagtggg gggccttctc actggctcgc tccgctccgc
    19141 gccaccgggt cggtcggcag cagcttccag ccgtgggcaa ggatcaccag gtgggtggcg
    19201 tcccgcgcgc ccgtgtcggc gaggagttgg tcgagtgcgg cgcgctggtc ggcgggggcg
    19261 agcttggcgg cgacggcgat gtcacggggg tcgctgtgct cggcgacggc tcggagcagc
    19321 acccgctgct ccggggtgag ggatggcgct ggccggtccg ccgtgggtga ggccacctgc
    19381 tgggtggtga acaggcggtg cacgatcacc gccggcttgc agcggggcgg gcagtgcagg
    19441 ctctcacgga tgtcgcggag gtactggcgg acggtcacgg gtgacaggac ggtctgcgtg
    19501 gcgatctctt gggccgagag gccgttagcg aggtgctggg cgacgcgttg cagggtcggc
    19561 gtcaggggtg tgatcggtgc gctggtcgtc acgggcgggg tcacggtgtc tctttcggct
    19621 gagttggtgg tcactgggag ggtgccgccg gtccccgcgg gggacggggc cagcggcacg
    19681 ggcccgtgcg cggcgatggg gagtcacggg gtgccgcgca cgggggctca tgcggcggtc
    19741 gggtcggggc gtgcccaggc ggcttcggcg gcgaggcgtt cggaccactg gatgtggtcc
    19801 tctccgaagg cggcgtcggc caggcggatg cgctggactt caccggtccc ggccggtgga
    19861 taggtgtact ggatgtcgcg ccacagacgc tggaggacgt agtcgcggtc gagggcgtgg
    19921 gcgccgtgca gttccatggc gtcctgggcg gactgcatgg cccaccggtg gccgaggtat
    19981 ttcgaattga tcagttcggc gtcgcagggc agaccttggt cgaggaggtg cacggcctgg
    20041 taggcgagta tccgggcggc gcgcaggcgg gcctccatgt cgccgacgcg gtcccgcagg
    20101 acgggcaggg cggacagggc gccctggtag cgggggcggg ccttgagccg ggcggtggtg
    20161 gtgtccacga cggcttcgtg gacgccgagg ctgacggcgg ccaggttggg acggccgtag
    20221 aggatgctgc tgctctgggc cacggccagt ccctggccga tctccccgac cacgttgtct
    20281 tcggggacgc ggacgtgatc gaggtcgagg cggccgacgg agaagccgtg cagaccgagg
    20341 ccggcacggt ggtcggggac ggagagtccg gggcggtcgg cttcgaccat gaacgcggtc
    20401 agagcctggg aggtgctgcc tccggccgcg gcggtgcggg cgacgatgag gtgggctccg
    20461 gcgaggtggc tgttgccgat atggatcttg ctgccggtga tcacccactc gttgccggtg
    20521 cgttcggcgg tggtctcgat gccgccgatg tgtccgccgg cgagcggttc ggtcacggcg
    20581 atcgacggca gcagggaacc gtccgcgacc cggggaagcc agcggccctt ctgctcgtag
    20641 gtggcgaagt gcagcacggc gcccacgggg atcaaggtgg cttgcaggat ggctgcggca
    20701 gccgccgaga cccgcgcgat gcggtggacc aagacggtcc tggctacgtg tccggcgccc
    20761 agcccgccga agacggccgg tacggtgacg gcgaaccagc cccgggcggc catcaggtcg
    20821 gcgatcttgc tttccgccct gcccggagcg gcctccatcc gcgcgacgcg cggcgcgacg
    20881 tgctcggtcg cgaaggcgtc cgcctcctgc cacagcatgt cgtggcgggc ggtgaggtag
    20941 ggacgcagcg ccggtggagg cgtggtgggt gtggcggaca tggtctccct ctccctggat
    21001 gaaggtcgca acgcggagcg gccggggatc gcctacggct cccgggtggg ggtgtggaac
    21061 ggcttagcgg acgggggcgc gggtgatgtg gtccatcacc tgtgcactgg cgttgatgac
    21121 gatgtcccgc agacggcggg cctcggccag gggccgcttc tcggggtcga tgacgcacac
    21181 cgttcccagc acggtgccgc tgtcgtggat cagcggtgcg ccgaagtagg agcggatccc
    21241 gacggcgtcg acgaccgcgt tgccgctgaa gcgcggggac gcgtgtacgt cgtggagcgg
    21301 gagggccttc ttacgggcca tgacctccgg gcaccagccg tggtcgcggc tcatggtgcg
    21361 gccgacgaag acgtacccac tgtccgcggg cggctggtgc agtccgacga aggtctgttc
    21421 ctccaggaac aggttgacaa acccgtactg gaacctggct cgtgtggcca tgtcgcgggc
    21481 caggtcgtcg aagtcctcgt tggccatggg gggcacgccc aggcggttga gcagctcgta
    21541 acgctgcgcc agctccagcg actgctgggg cggcttgctg gagaggacgg tgccgggcgg
    21601 agtgagcggg ccgcgggtgg tgtcccgcat gtcgcgccga ggcaaggacc gggcgggcgg
    21661 ggcagtctgc ggcgtgcggt aggggtcgct ggggtgctgt gacatcaggc gtcctggagg
    21721 gtggtagaag gggtgtgacc agcgcgatta gtggtggcgg cgcaattcac ggcgtggtcg
    21781 acgagggcca gcagaacgcc ggcgacatga ttcggctcgc gggcgtcgca ggtgaccacc
    21841 ggcacggcag cggggagttc gagagcggcg cggacctgct cggggtggta gcggtgcgcc
    21901 ccgtcgaacc ggttcaccgc gacgacgaag ggcaggccga tgtcctcgaa aaagctgacg
    21961 ggcgtgaagc tgctctccaa gcggcgggtg tcgaccagga cgaccgcgcc gacggcgccg
    22021 cgggagaggt cgtaccaaag gtcgacgaac cggtcctggc ccggcgtgcc gaacaggaac
    22081 agctccaaag gcatcggcgc gtcgggcaag ctcaggcggc cgaagtcgaa ggcgaccgtg
    22141 gtggtccgct tggacgccag gccagccagg ctgtcgacgt ccgcgctcgc ctcggtcagg
    22201 tactcctccg tactcagcgg cgtgatctcg ctgacggcgc ccactgcggt ggtcttgccc
    22261 gcgccgaaac cgccggcgat catgatcttc agcacggtcg gcgcaccggc ccgcgggtgc
    22321 ggcgaaaccg tggacgggtc atccggcctg gggataggcg acggcatcag gccacttcct
    22381 cttcaagccg acggaaacgg ctgccagcat ttggatagac ggaccggacc ctgcgccggt
    22441 atcggcatag gactgggtca gggggacgac gagggcgtcg gcgtccagga ggtcggagac
    22501 gagaactttg acggcggtca cgggccggcc gaggcggccc gccagctcga ccaccgaccg
    22561 ccggcgctcc cggcacaggg cgagaatctc cccgcactcc tcggcctgcg ccgggcccgg
    22621 ccttccccgc ccggcctcca ggacggtttc cagagcgagc aggtgccgcg gcttggtacg
    22681 cccgcgcgtc acggcggagg tccgcacgaa cgccgactcc tcggccgcgc ggccgtacgt
    22741 gctcaccgga cctcgccgcc cgtgccaacg cggacgggga tcaccatgta cggggcgaac
    22801 ttctggacca ggcgccccat ctcgaagccg acggtgccca cgtcggcgtc cctggcggcg
    22861 atgacagcga ggatcgtgtc cacctcaccg cgttcgttac cggggtggtt gtcgaaggcc
    22921 gcgctgcgcc cggcgctctg gacgaagaac aggcagtcgt ctcgctcgat gatgacctgg
    22981 cccgcaggcc tcttcttccc acgcggaccg gtgatgttcg ccgagaggga ggccaccccg
    23041 ctgaaggcgg ccgacagctc gtccgcccag tccttgtcga cgtcactgtc cagcagccgc
    23101 agtccgtcgc gcgagagcag gacggcgtgc gtgacaccca gcgtctcgga ggcgaactga
    23161 cgcagcagcc agaccatgct gtcccgctgt ccgcttgtgg tcgtcgcgga tgcgggcatg
    23221 tcgccggtca tgttgttcat cgcggggtgg gtactcatag ggatcgctcc agaaggggga
    23281 agggccagtg gatgtgccgg gccaccggga acggacgggt cagggggtgg ggtgttctgc
    23341 cggggcggga gggcaatcgg cggtgccgcc ggcctggagg ccgttgcgga aggcggctgc
    23401 cagcccgggc gtcgccgcgg ccacgggggc ttgctcccgc tcgtgcggtg gacggaaagg
    23461 ttccgtccgg cgtgtgcgcg tcggcagagc gggcgcgtca gccgactgac ctgcctctgc
    23521 ggtcggcgcc ccagtggcac ccgggcgtgc ggcttgatgc gcccccgagg cggctggagc
    23581 cgcggccacc tgctgcggct gccgcccgga cgttccagct ccctcgggcg gcggagcgcc
    23641 cgcgtcctcg accgatggaa tagctaccag gagccgtgcc ggtatgacga ccaggacggt
    23701 ggtgcctccc gtcgcgttct cctgcaggag gacggacaac ccgtgtgact gggcgatctt
    23761 cgcggcgacc agcaggccga gctgaccagc ccggacctgg ccgctgacgt cgacctcgtg
    23821 cggggctttg agcaggtggt tcatctgtgc ccgcgtctgc ggatgcatgg ggatggcgcg
    23881 gtcctcgacc tcgatggcca gcccgtgtgg cacccgctgc gcgcgcacca tcacccgcgt
    23941 ctctggatcc gagcactcgc aggcgttctc gatcagctcg gccagcaggt gcgtcaggtc
    24001 cggccccaca tggccgggca accccaactc ggcgcccacg gatccggccg cgacggccac
    24061 ccgcggatac tgcacgacct cggagacagc gccacgcagg gccgtcgtga cgggaacggg
    24121 ccggcgcacg ctgcgcaggg actgcccgcc caggaccgcc gtgctctcga cctggcggcg
    24181 catccgcgtc acgaggtgat cgatctcgaa gatcttggcc agcagctctg ggtcgtcggt
    24241 cagcatctcc agctggctca gtgcctcaag tgccttgctg accaaggcgt gctcgcgcat
    24301 ggccaggcgg cgaagcactt ccaggaggac cacggactgg gactcgtcgt gcacgcggat
    24361 cagcgacatg atggcctgcg cctggagggc actcagcgcg ttgtcgatct cggcgttcgg
    24421 agtgggcgac tgcgcggtgt gcgggtccgg caacgctgga cgttttccgc ggcacagctc
    24481 gtccgccgac cactgcaccg acttcccaac ggctgccgct gcccctgcga ccgctgtcag
    24541 cgctgctgcc tgggactcct ccactgccga gtgcacggca ccggcgacgg tgcgtgttcc
    24601 gtgtgccgcc accgcggcga ccccggacag cccgcagatc aggccggcca ggacccagcc
    24661 ggggcctacg acggacaccg accagagaac gacagcggcg agcagcaacg cggcaaggag
    24721 caccaggggc agtgtcacgg cgcgccgggc gaggagcagc atgttcgcgt cgcccggggg
    24781 ccgccgtctg cggtggccgg tagcggctgg ccgtgccggg aaggcgctgt cagacatggg
    24841 aatcctcgtc aggggggtgg gtggctaagc gagctgcggc gtcaggtctg cggtgctctg
    24901 gcgcgtgctg cgggaggtcg agcggcgcgc cggaaccgcg accgcacctt ggcgggggga
    24961 ggactgcgtc gcgatctgct gaaggagcag ggcgctctgg atcaggccca tgtggctgaa
    25021 tgcctgcggg aagttgccga gctggcgctg ctggacgggg tcgtactcct ccgccaggag
    25081 gccaaggtcg ttgcgcagag ccaggaggcg ttcgaacaag gcgcgggcct cgtcgaggcg
    25141 gcctgtcagg gcgaggccgt cgacgaacca gaaggcgcac aggaagaagg cgccctcgtc
    25201 gccggtcaag ccgtccgccc cggcgtcctc actgcaggtc gggtaccggt acacgagccc
    25261 gtcgtccgtg gagagttcac gacgtacggc gtccacggtg ccgatgacgc gcgggtcgtc
    25321 gggcggcagg aagccggtgc gggggatgag caacgtagcg gcgtccagtt cctgcgagcc
    25381 gtaggcctgg gtgaaggtgt tgcgcaccgg gtcgaagccc ttgtcacaga cctcccggtg
    25441 gatcgccgcc cgcagctcga ccagcggggc cacgtccatg tcgagcgcgc cggcttcggc
    25501 aaggcggatg gtgcggtcga ccgccaccca ggccatcacc ttggaatgga cgaagtgccg
    25561 gcgggccccg cggatctccc agatgccctc gtcgggctcc cgccagcgcc gggccaggtg
    25621 ctggatgagc tgccggtgca ggaccgcggt gtcggcgcag tgggcgactc cgctctggta
    25681 cgcgaggtac agggtgtcga tgacctcgcc gtacacgtcg agctggagct ggtccgctgc
    25741 gccgtttccg acgcgtaccg gggaggagcc ctcgtacccg ggaagccagg gaagctcccg
    25801 ctcccgcagg tcacggtccc cggtgatccc gtacatgatc tgcaggttct ccgggtctcc
    25861 ggccacggcg cgcaggagcc atcgccgcca tgcctgtgcc tcctgcaggt atccggtccc
    25921 cagtagcgcg gccaaggtgg tggaagcgtc gcgcagccag ctatagcggt aatcccagtt
    25981 ccgctggccg ccgatctcct cgggcagcga cgtggtcggc gccgcgacga tcccgccgct
    26041 cggcccgtag gtcatggcct tcaacgcgat cgaggaccgg accacggcct cgcggtaggg
    26101 cccgttgtag gtgcactcct gcgtccagtc ctgccagaag gcgagcgtct cggcgagcgc
    26161 ggcttccggg tcaggaatgt ccggtgcggg ggcgtgggac gggcaccagc tgagcacgaa
    26221 cgccacgctc tgcccggcgc tgatggcgaa ggtgctgacg accacgtcgt ccttctccat
    26281 ctgcggtacg caggtgtcga gccacagggc gtccgcgccg gcctccgcga ccatgcggcc
    26341 ctcgacctcg tggatccatg gaccgacgct gccgtatccc ggcctcgggc gcatggccga
    26401 gagcatctcc acgtcgccgg tcaggccctc gacgatccgg atcacctgtg gggt
//
