LOCUS       NC_003888              48144 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    .
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2023-11-22 14:16:39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 7570411
            Orig. end    :: 7618555
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     cand_cluster    1..48144
                     /SMILES="C(C)CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(t2pks2 or ksIII)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="neighbouring"
                     /product="PKS-like"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..48144
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="PKS-like"
                     /product="T1PKS"
                     /region_number="23"
                     /rules="(t2pks2 or ksIII)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     protocluster    1..41041
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21041]"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21041
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
     cand_cluster    1..41041
                     /SMILES="C(C)CC(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(t2pks2 or ksIII)"
                     /kind="single"
                     /product="PKS-like"
                     /protoclusters="1"
                     /tool="antismash"
     gene            complement(195..557)
                     /db_xref="GeneID:1102247"
                     /gene_synonym="SC1A2.17c"
                     /locus_tag="SCO6808"
     CDS             complement(195..557)
                     /codon_start=1
                     /db_xref="GeneID:1102247"
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 76.1; E-value: 2.6e-23)"
                     /gene_kind="regulatory"
                     /gene_synonym="SC1A2.17c"
                     /locus_tag="SCO6808"
                     /note="SC1A2.17c, possible ArsR-family transcriptional
                     regulator, len: 120 aa. Similar to several regulators
                     including: Streptomyces coelicolor TR:Q9X8X8
                     (EMBL:AL078610) transcriptional regulator, SCH35.28C (122
                     aa), fasta scores opt: 297 z-score: 392.7 E(): 1.8e-14
                     49.4% identity in 87 aa overlap and Mycobacterium
                     tuberculosis TR:P71941 (EMBL:Z80225) transcriptional
                     regulator (126 aa), fasta scores opt: 262 z-score: 348.0
                     E(): 5.6e-12 38.1% identity in 113 aa overlap. Contains a
                     Pfam match to entry PF01022 HTH_5, Bacterial regulatory
                     protein, arsR family with the helix-turn-helix motif
                     situated between residues 56..77 (+4.54 SD)."
                     /product="transcription regulator ArsR"
                     /protein_id="NP_630880.1"
                     /transl_table=11
                     /translation="MSDDGFLEGGSCGPGLNCQPLERSEAEQLSTILRSIADPTRLQLF
                     RLLEQAPDGEACVCDLADSLGLRQSTVSHHLKIMTEAGLLDRERRGTWAWFSVNHEGLR
                     RIRSILDPAPQATKEL"
     misc_feature    complement(219..461)
                     /gene_synonym="SC1A2.17c"
                     /locus_tag="SCO6808"
                     /note="Pfam match to entry PF01022 HTH_5, Bacterial
                     regulatory protein, arsR family, score 85.20, E-value
                     1.4e-21"
     PFAM_domain     complement(300..446)
                     /aSDomain="HTH_5"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01022.23"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory protein, arsR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6808_0885"
                     /evalue="3.50E-17"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO6808"
                     /locus_tag="SCO6808"
                     /protein_end="86"
                     /protein_start="37"
                     /score="62.1"
                     /tool="antismash"
                     /translation="DPTRLQLFRLLEQAPDGEACVCDLADSLGLRQSTVSHHLKIMTEA
                     GLLD"
     gene            complement(696..1925)
                     /db_xref="GeneID:1102248"
                     /gene_synonym="SC1A2.18c"
                     /locus_tag="SCO6809"
     CDS             complement(696..1925)
                     /codon_start=1
                     /db_xref="GeneID:1102248"
                     /gene_functions="transport (smcogs) SMCOG1137:Major
                     facilitator superfamily MFS 1 (Score: 115.4; E-value:
                     4.2e-35)"
                     /gene_kind="transport"
                     /gene_synonym="SC1A2.18c"
                     /locus_tag="SCO6809"
                     /note="SC1A2.18c, possible integral membrane transport
                     protein, len: 409 aa. Similar to several membrane transport
                     proteins e.g. Listeria monocytogenes TR:Q9X769
                     (EMBL:AJ009627) multi drug resistance transporter (397 aa),
                     fasta scores opt: 241 z-score: 264.5 E(): 2.5e-07 23.0%
                     identity in 344 aa overlap. Contains multiple possible
                     membrane spanning hydrophobic domains and a Prosite hit to
                     PS00402 Binding-protein-dependent transport systems inner
                     membrane comp sign."
                     /product="integral membrane transport protein"
                     /protein_id="NP_630881.1"
                     /transl_table=11
                     /translation="MSYRSMASPAAALNQPTRPRAALPALCLTQITSWGIVYYAFPVLN
                     PQITMATGWSATATTAAFSAALLMSAVAGIRIGRILDARGPRTVMTVGSVVGTVSLVII
                     ASAPNLTVFTAGWLLAGFAMASTFYQPAFAALTRWWAPNHVRALTIVTLAGGLASTVFA
                     PLTAQLANHFSWRHTYLLLALVLATVTVPVHAYALRGPWPPAPPPSTTGETASTTVITR
                     SRPFLLLATALTLSAFATYAVVITLVPLLLDRGYTAAEAAWALGLGGAGQTLGRTLYAP
                     LARRSSPALRAAVLIGMGGVTTAAFALIPGPYGLLAALAVIAGTVRGNLTLLQATAITD
                     RWGAHRYGRLSGLLAAPTTTASALAPFAGTALAAPLGGYPRLFSALALASAAAALIAWY
                     TAPTPAARKP"
     PFAM_domain     complement(993..1844)
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07690.19"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6809_0886"
                     /evalue="5.10E-21"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO6809"
                     /locus_tag="SCO6809"
                     /protein_end="311"
                     /protein_start="27"
                     /score="75.1"
                     /tool="antismash"
                     /translation="LTQITSWGIVYYAFPVLNPQITMATGWSATATTAAFSAALLMSAV
                     AGIRIGRILDARGPRTVMTVGSVVGTVSLVIIASAPNLTVFTAGWLLAGFAMASTFYQP
                     AFAALTRWWAPNHVRALTIVTLAGGLASTVFAPLTAQLANHFSWRHTYLLLALVLATVT
                     VPVHAYALRGPWPPAPPPSTTGETASTTVITRSRPFLLLATALTLSAFATYAVVITLVP
                     LLLDRGYTAAEAAWALGLGGAGQTLGRTLYAPLARRSSPALRAAVLIGMGGVTTAAFAL
                     IPG"
     misc_feature    complement(996..1082)
                     /gene_synonym="SC1A2.18c"
                     /locus_tag="SCO6809"
                     /note="PS00402 Binding-protein-dependent transport systems
                     inner membrane comp sign."
     protocluster    1068..48144
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[21067:28144]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      21068..28144
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1068..48144
                     /SMILES="C(C)CC(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="2"
                     /tool="antismash"
     gene            complement(1932..2390)
                     /db_xref="GeneID:1102249"
                     /gene_synonym="SC1A2.19c"
                     /locus_tag="SCO6810"
     CDS             complement(1932..2390)
                     /codon_start=1
                     /db_xref="GeneID:1102249"
                     /gene_synonym="SC1A2.19c"
                     /locus_tag="SCO6810"
                     /note="SC1A2.19c, unknown, len: 152 aa. Highly similar to
                     proteins of undefined function from Mycobacterium
                     tuberculosis SW:YQ11_MYCTU (EMBL:Z80225) (152 aa), fasta
                     scores opt: 509 z-score: 630.7 E(): 1e-27 55.0% identity in
                     149 aa overlap and Bacillus subtilis SW:YQCK_BACSU
                     (EMBL:D32216) (146 aa), fasta scores opt:349 z-score: 437.2
                     E():6e-17 34.9% identity in 152 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_630882.1"
                     /transl_table=11
                     /translation="MSRIQLALRVPDLQSAIAFYSKLLDTEPAKLRDGYANFAVTEPPL
                     KLVLIEGEEGTDTRLDHLGVEVASTEDVAAATARLSQAGLSTREENDTACCYALQDKVW
                     VHGPGQEAWEVYVVKADADTLAKQPGSTCCAPTDAVQPGPQATTTSCC"
     PFAM_domain     complement(2109..2375)
                     /aSDomain="Glyoxalase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00903.28"
                     /description="Glyoxalase/Bleomycin resistance
                     protein/Dioxygenase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6810_0887"
                     /evalue="6.70E-10"
                     /label="SCO6810"
                     /locus_tag="SCO6810"
                     /protein_end="94"
                     /protein_start="5"
                     /score="39.4"
                     /tool="antismash"
                     /translation="LALRVPDLQSAIAFYSKLLDTEPAKLRDGYANFAVTEPPLKLVLI
                     EGEEGTDTRLDHLGVEVASTEDVAAATARLSQAGLSTREENDTA"
     regulatory      complement(2399..2403)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(2458..3852)
                     /db_xref="GeneID:1102250"
                     /gene_synonym="SC1A2.20c"
                     /locus_tag="SCO6811"
     CDS             complement(2458..3852)
                     /codon_start=1
                     /db_xref="GeneID:1102250"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="other (smcogs) SMCOG1092:hypothetical
                     protein (Score: 61.5; E-value: 1.4e-18)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC1A2.20c"
                     /locus_tag="SCO6811"
                     /note="SC1A2.20c, possible hypothetical protein, len: 464
                     aa. The N-terminus is highly similar to Streptomyces
                     coelicolor TR:Q9X8X7 (EMBL:AL078610) hypothetical protein,
                     SCH35.29 (162 aa), fasta scores opt: 753 z-score: 813.4
                     E(): 0 71.2% identity in 146 aa overlap. Contains a
                     possible N-terminal signal sequence."
                     /product="hypothetical protein"
                     /protein_id="NP_630883.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.4e-10, bitscore:
                     39.7, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 1e-06, bitscore: 27.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPAVLTPPVVVIGAGPIGLAAAAHLLERGLRPLVLEAGPTAGS
                     AVSEWAHVRLFSTWGEVVDPAAEKLLTPTGWSRPDSSTYPSGGDWVKHYLQPLADTLGD
                     QIRYGARVTGVSKAGRDRVVDADRDAQPYVVQVKHTDGREERITASAVIDASGTWSLPS
                     PAGSSGLPALGEHMASDHVTYRVPDLTDPAVRARYAEKRTAVIGSGASAFTALASLAEL
                     ARSQNSATTKTVWVLRRGLSGSTYGGGEADQLPARGALGLAAKAAVDEGHAEAVTGFRT
                     EAVERGAEDRLILVAEDGRRLQAVDEVIVLTGFRPDLSFLSEVRLRLDERLQAPVELAP
                     LIDPNQHSCGTVYPHGHRELSHPDSGVYLVGMKSYGRAPTFLAMTGYEQVRSIAAALAG
                     ETEAADRVELVLPETGVCGGSGLFDTDGAAEPEKEGCCAPSAPQLVQLSTISPGPATTP
                     GSSCNA"
     PFAM_domain     complement(2860..3819)
                     /aSDomain="Pyr_redox_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13738.9"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6811_0888"
                     /evalue="4.10E-14"
                     /label="SCO6811"
                     /locus_tag="SCO6811"
                     /protein_end="331"
                     /protein_start="11"
                     /score="52.7"
                     /tool="antismash"
                     /translation="VVIGAGPIGLAAAAHLLERGLRPLVLEAGPTAGSAVSEWAHVRLF
                     STWGEVVDPAAEKLLTPTGWSRPDSSTYPSGGDWVKHYLQPLADTLGDQIRYGARVTGV
                     SKAGRDRVVDADRDAQPYVVQVKHTDGREERITASAVIDASGTWSLPSPAGSSGLPALG
                     EHMASDHVTYRVPDLTDPAVRARYAEKRTAVIGSGASAFTALASLAELARSQNSATTKT
                     VWVLRRGLSGSTYGGGEADQLPARGALGLAAKAAVDEGHAEAVTGFRTEAVERGAEDRL
                     ILVAEDGRRLQAVDEVIVLTGFRPDLSFLSEVRLRLDER"
     gene            4009..4368
                     /db_xref="GeneID:1102251"
                     /gene_synonym="SC1A2.21"
                     /locus_tag="SCO6812"
     CDS             4009..4368
                     /codon_start=1
                     /db_xref="GeneID:1102251"
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 80.4; E-value: 1.2e-24)"
                     /gene_kind="regulatory"
                     /gene_synonym="SC1A2.21"
                     /locus_tag="SCO6812"
                     /note="SC1A2.21, possible ArsR-family transcriptional
                     regulator, len: 119 aa. Highly similar to several
                     including: Streptomyces coelicolor TR:Q9X8X8
                     (EMBL:AL078610) transcriptional regulator, SCH35.28C (122
                     aa), fasta scores opt: 485 z-score: 630.1 E(): 1.1e-27
                     69.7% identity in 99 aa overlap and Mycobacterium
                     tuberculosis TR:P71941 (EMBL:Z80225) transcriptional
                     regulator (126 aa), fasta scores opt:378 z-score: 494.4
                     E(): 3.9e-20 59.8% identity in 97 aa overlap. Also similar
                     to the adjoining CDS SC1A2.22 (113 aa), fasta scores opt:
                     292 z-score: 353.0 E(): 3.1e-14 51.1% identity in 94 aa
                     overlap. Contains a Pfam match to entry PF01022 HTH_5,
                     Bacterial regulatory protein, arsR family."
                     /product="transcription regulator ArsR"
                     /protein_id="NP_630884.1"
                     /transl_table=11
                     /translation="MSNLALDSTNVNATGSWCCQPLGKEELSAADSEKIAVMFKALSDP
                     VRLRLFSKIAARPGGEACVCDIQDVGVSQPTVSHHLRKLREAGLLESERRASWVYYRVA
                     PGVLSAMAGLLSQTT"
     misc_feature    4123..4362
                     /gene_synonym="SC1A2.21"
                     /locus_tag="SCO6812"
                     /note="Pfam match to entry PF01022 HTH_5, Bacterial
                     regulatory protein, arsR family, score 93.10, E-value
                     5.6e-24"
     PFAM_domain     4138..4284
                     /aSDomain="HTH_5"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01022.23"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory protein, arsR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6812_0889"
                     /evalue="1.60E-13"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO6812"
                     /locus_tag="SCO6812"
                     /protein_end="92"
                     /protein_start="43"
                     /score="50.4"
                     /tool="antismash"
                     /translation="DPVRLRLFSKIAARPGGEACVCDIQDVGVSQPTVSHHLRKLREAG
                     LLES"
     regulatory      4473..4477
                     /regulatory_class="ribosome_binding_site"
     gene            4486..4827
                     /db_xref="GeneID:1102252"
                     /gene_synonym="SC1A2.22"
                     /locus_tag="SCO6813"
     CDS             4486..4827
                     /codon_start=1
                     /db_xref="GeneID:1102252"
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 70.6; E-value: 1.3e-21)"
                     /gene_kind="regulatory"
                     /gene_synonym="SC1A2.22"
                     /locus_tag="SCO6813"
                     /note="SC1A2.22, possible ArsR-family transcriptional
                     regulator, len: 129 aa. Highly similar to several
                     including: Streptomyces coelicolor TR:Q9X8X8
                     (EMBL:AL078610) transcriptional regulator, SCH35.28C (122
                     aa), fasta scores opt: 271 z-score: 365.4 E(): 6e-13 50.0%
                     identity in 92 aa overlap and Mycobacterium tuberculosis
                     TR:P71941 (EMBL:Z80225) transcriptional regulator (126 aa),
                     fasta scores opt: 214 z-score: 291.6 E(): 7.7e-09 59.4%
                     identity in 64 aa overlap. Also similar to the adjoining
                     CDS SC1A2.21 (119 aa), fasta scores opt: 292 z-score: 353.0
                     E(): 3.1e-14 51.1% identity in 94 aa overlap. Contains a
                     Pfam match to entry PF01022 HTH_5, Bacterial regulatory
                     protein, arsR family."
                     /product="transcription regulator ArsR"
                     /protein_id="NP_630885.1"
                     /transl_table=11
                     /translation="MCQKGAGSACDGTCLELTAADMVWWSNVFKTLGDPVRLQLLMKLA
                     ERSGGEAAVHELADVGVSPATVSHHLKRLRCIGLIESRRDGRLVYYKLGAGVRAALMQI
                     LHQRSQVGA"
     misc_feature    4570..4818
                     /gene_synonym="SC1A2.22"
                     /locus_tag="SCO6813"
                     /note="Pfam match to entry PF01022 HTH_5, Bacterial
                     regulatory protein, arsR family, score 74.40, E-value
                     2.3e-18"
     PFAM_domain     4585..4731
                     /aSDomain="HTH_5"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01022.23"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory protein, arsR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6813_0890"
                     /evalue="1.00E-11"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO6813"
                     /locus_tag="SCO6813"
                     /protein_end="82"
                     /protein_start="33"
                     /score="44.6"
                     /tool="antismash"
                     /translation="DPVRLQLLMKLAERSGGEAAVHELADVGVSPATVSHHLKRLRCIG
                     LIES"
     gene            complement(4948..5619)
                     /db_xref="GeneID:1102253"
                     /gene_synonym="SC1A2.23c"
                     /locus_tag="SCO6814"
     CDS             complement(4948..5619)
                     /codon_start=1
                     /db_xref="GeneID:1102253"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 151.8; E-value:
                     4.2e-46)"
                     /gene_kind="transport"
                     /gene_synonym="SC1A2.23c"
                     /locus_tag="SCO6814"
                     /note="SC1A2.23c, possible ABC transporter ATP-binding
                     component, len: 223 aa. Similar to many ABC transporters
                     including: Deinococcus radiodurans TR:AAF12204
                     (EMBL:AE001862) phosphate ABC transporter, ATP-binding
                     protein (254 aa), fasta scores opt: 458 z-score: 524.0 E():
                     8.7e-22 38.1% identity in 210 aa overlap and Escherichia
                     coli SW:PSTB_ECOLI (EMBL:X02723) phosphate ABC transporter,
                     ATP-binding protein, PstB(257 aa), fasta scores opt: 436
                     z-score: 499.3 E(): 2.1e-20 38.9% identity in 198 aa
                     overlap. Contains Prosite hits to PS00211 ABC transporters
                     family signature and PS00017 ATP/GTP-binding site motif A
                     (P-loop). Also contains a Pfam match to entry PF00005
                     ABC_tran, ABC transporter."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_630886.1"
                     /transl_table=11
                     /translation="MRELRVRSRDKNLVGPVSFSLKHGSTTGLCGPSGVGKSTVLRALV
                     ELLPNGLTRDGELQVLDRTIAPGKGDADLRSKIVLVPQTPVVFGGSILDNALFGLRHLL
                     RASQEVLRERAEKALEEAGLWKEVADRLDSPAQNLSAGQRQRLCLARALALEPAGLLLD
                     EPTSALDERSRDKVEQSISALRGSRAVLLVSHDPAQVERLCDTTVHLDQPVTASTPAAV
                     G"
     misc_feature    complement(4981..5550)
                     /gene_synonym="SC1A2.23c"
                     /locus_tag="SCO6814"
                     /note="Pfam match to entry PF00005 ABC_tran, ABC
                     transporter, score 185.10, E-value 1.1e-51"
     PFAM_domain     complement(5119..5574)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00005.30"
                     /db_xref="GO:0005524"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6814_0891"
                     /evalue="2.90E-27"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /label="SCO6814"
                     /locus_tag="SCO6814"
                     /protein_end="167"
                     /protein_start="15"
                     /score="96.0"
                     /tool="antismash"
                     /translation="PVSFSLKHGSTTGLCGPSGVGKSTVLRALVELLPNGLTRDGELQV
                     LDRTIAPGKGDADLRSKIVLVPQTPVVFGGSILDNALFGLRHLLRASQEVLRERAEKAL
                     EEAGLWKEVADRLDSPAQNLSAGQRQRLCLARALALEPAGLLLDEPTS"
     misc_feature    complement(5161..5205)
                     /gene_synonym="SC1A2.23c"
                     /locus_tag="SCO6814"
                     /note="PS00211 ABC transporters family signature"
     misc_feature    complement(5506..5529)
                     /gene_synonym="SC1A2.23c"
                     /locus_tag="SCO6814"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     gene            complement(5625..7436)
                     /db_xref="GeneID:1102254"
                     /gene_synonym="SC1A2.24c"
                     /locus_tag="SCO6815"
     CDS             complement(5625..7436)
                     /codon_start=1
                     /db_xref="GeneID:1102254"
                     /gene_functions="transport (smcogs) SMCOG1069:putative ABC
                     transporter permease protein (Score: 36; E-value: 8.8e-11)"
                     /gene_kind="transport"
                     /gene_synonym="SC1A2.24c"
                     /locus_tag="SCO6815"
                     /note="SC1A2.24c, bi-domain ABC transporter permease, len:
                     603 aa. The N-terminus and C-terminus appear to be discrete
                     domains, both of which are similar to many ABC transporter
                     permeases e.g. The N-terminus is similar to
                     Methanobacterium thermoautotrophicum TR:O27762
                     (EMBL:AE000929) phosphate transporter permease (291 aa),
                     fasta scores opt: 467 z-score: 511.4 E(): 4.5e-21 32.5%
                     identity in 268 aa overlap. The C-terminal is similar to
                     Escherichia coli SW:PSTA_ECOLI (EMBL:X02723) phosphate
                     transport system permease, PstA (296 aa), fasta scores opt:
                     396 z-score: 434.6 E(): 8.4e-17 30.1% identity in 286 aa
                     overlap. Contains 2x Prosite hits to PS00402
                     Binding-protein-dependent transport systems inner membrane
                     comp sign and 2x Pfam matches to entries PF00528
                     BPD_transp, Binding-protein-dependent transport systems
                     inner membrane component. Contains multiple possible
                     membrane spanning hydrophobic domains."
                     /product="ABC transporter permease"
                     /protein_id="NP_630887.1"
                     /transl_table=11
                     /translation="MTTKTLTRPPVAPEVGSRPRASKWIWSWLYGGAFAVAALLLTVIG
                     YLGAGLASGHVNWLELLTEKAWSPTSSVYGGLAMIYGTAVVSALALVIAVPISWAAAVA
                     LSEYLPPRLSRPLRMCVELLAAVPSIVYGLIGIMVVRPVIAQIADVPGGDSLAAAGIVL
                     AVMITPTIVAVSVDALAAVPDRVRESAYSLGLTRREVVRSAVLPLARSGMRAAVLLGLA
                     RALGEAIAVFLVVGRADGRLPTSFGGFLDSLSHPGQTLTTKLAGPEPVLAGTSGPYFAA
                     LCALGLILLALVAAATIWGTRSRTRKNAAARTPRFRGTSRMRLQRDRLVMTLRLGALLL
                     PSALLLGMLGLLVTRGSSAFNPSFWFSSATGAAGGGVRDQIVGTVLLILATGILALPLG
                     FGAGILIGVHASERTARVLQTFTVVLGGAPTILLGLAGFVILSTSMGWGRSWLAGAIVL
                     VPVVVPVIALTTSARVRSIPPELKESAMSLGLTRAQFVRSVVVPYTWPATITGLLLGLA
                     RAAGETAPLIFTATVFFGAPALPSGIVEAPVQALPTHIFTLSQDSGDPQAVTQAWGSAM
                     VLVIITAVLLSAAVALRNRFEGERWTT"
     PFAM_domain     complement(5655..6242)
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00528.25"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6815_0893"
                     /evalue="1.10E-17"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO6815"
                     /locus_tag="SCO6815"
                     /protein_end="594"
                     /protein_start="398"
                     /score="64.5"
                     /tool="antismash"
                     /translation="GFGAGILIGVHASERTARVLQTFTVVLGGAPTILLGLAGFVILST
                     SMGWGRSWLAGAIVLVPVVVPVIALTTSARVRSIPPELKESAMSLGLTRAQFVRSVVVP
                     YTWPATITGLLLGLARAAGETAPLIFTATVFFGAPALPSGIVEAPVQALPTHIFTLSQD
                     SGDPQAVTQAWGSAMVLVIITAVLLSAAVALRN"
     misc_feature    complement(5757..6020)
                     /gene_synonym="SC1A2.24c"
                     /locus_tag="SCO6815"
                     /note="Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 36.40, E-value 6.3e-07"
     misc_feature    complement(5931..6017)
                     /gene_synonym="SC1A2.24c"
                     /locus_tag="SCO6815"
                     /note="PS00402 Binding-protein-dependent transport systems
                     inner membrane comp sign."
     PFAM_domain     complement(6537..7151)
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00528.25"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6815_0892"
                     /evalue="1.60E-16"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO6815"
                     /locus_tag="SCO6815"
                     /protein_end="300"
                     /protein_start="95"
                     /score="60.7"
                     /tool="antismash"
                     /translation="PISWAAAVALSEYLPPRLSRPLRMCVELLAAVPSIVYGLIGIMVV
                     RPVIAQIADVPGGDSLAAAGIVLAVMITPTIVAVSVDALAAVPDRVRESAYSLGLTRRE
                     VVRSAVLPLARSGMRAAVLLGLARALGEAIAVFLVVGRADGRLPTSFGGFLDSLSHPGQ
                     TLTTKLAGPEPVLAGTSGPYFAALCALGLILLALVAAATIWG"
     aSDomain        complement(6555..7337)
                     /aSDomain="TIGR02138"
                     /aSTool="tigrfam"
                     /description="phosphate_pstC: phosphate ABC transporter,
                     permease protein PstC"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6815_0103"
                     /evalue="1.60E-63"
                     /identifier="TIGR02138"
                     /label="SCO6815"
                     /locus_tag="SCO6815"
                     /protein_end="294"
                     /protein_start="33"
                     /score="212.5"
                     /tool="antismash"
                     /translation="FAVAALLLTVIGYLGAGLASGHVNWLELLTEKAWSPTSSVYGGLA
                     MIYGTAVVSALALVIAVPISWAAAVALSEYLPPRLSRPLRMCVELLAAVPSIVYGLIGI
                     MVVRPVIAQIADVPGGDSLAAAGIVLAVMITPTIVAVSVDALAAVPDRVRESAYSLGLT
                     RREVVRSAVLPLARSGMRAAVLLGLARALGEAIAVFLVVGRADGRLPTSFGGFLDSLSH
                     PGQTLTTKLAGPEPVLAGTSGPYFAALCALGLILLALVA"
     misc_feature    complement(6675..6905)
                     /gene_synonym="SC1A2.24c"
                     /locus_tag="SCO6815"
                     /note="Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 36.30, E-value 7.2e-07"
     misc_feature    complement(6816..6902)
                     /gene_synonym="SC1A2.24c"
                     /locus_tag="SCO6815"
                     /note="PS00402 Binding-protein-dependent transport systems
                     inner membrane comp sign."
     gene            complement(7440..8312)
                     /db_xref="GeneID:1102255"
                     /gene_synonym="SC1A2.25c"
                     /locus_tag="SCO6816"
     CDS             complement(7440..8312)
                     /codon_start=1
                     /db_xref="GeneID:1102255"
                     /gene_synonym="SC1A2.25c"
                     /locus_tag="SCO6816"
                     /note="SC1A2.25c, possible ABC transporter binding
                     lipoprotein, len: 290 aa. Similar to several including:
                     Escherichia coli SW:PSTS_ECOLI (EMBL:K01992)
                     phosphate-binding protein precursor (346 aa), fasta scores
                     opt: 158 z-score: 176.7 E(): 0.019 25.9% identity in 259 aa
                     overlap and Methanobacterium thermoautotrophicum TR:O27760
                     (EMBL:AE000929) phosphate-binding protein, PstS (271 aa),
                     fasta scores opt: 510 z-score: 554.5 E(): 1.8e-23 34.9%
                     identity in 281 aa overlap. Contains an appropriately
                     positioned Prosite hit to PS00013 Prokaryotic membrane
                     lipoprotein lipid attachment site, a Pfam match to entry
                     PF01449 PstS, Phosphate-binding protein and a possible
                     N-terminal signal sequence."
                     /product="ABC transporter binding lipoprotein"
                     /protein_id="NP_630888.1"
                     /transl_table=11
                     /translation="MFSKKRRLACLVTSVLAVVSLAGCADGGAGKSGALQVSGSTTVAP
                     VAADAAEALKADGLDITVATQGGSAGGISQLASGQITIALSSKPLSEEDKAANPDTDFV
                     STQIGADAVGIIVTKQVADAGVKNLTADQVRDLFEGKIKNWSEVGGPDLDVFVYDKEPG
                     RGTREVLDKYIYGDEKAPPPPESGNFAIVGGNLETRNKLESTPGAVAPLSTSFVEGRDR
                     LAAVTLDGIEASPENIATGKYPMSRPLYLITDGKPEGTAKKFIDYVLSAKGQALMTKHD
                     YLTLKEIGK"
     misc_feature    complement(7455..8222)
                     /gene_synonym="SC1A2.25c"
                     /locus_tag="SCO6816"
                     /note="Pfam match to entry PF01449 PstS, Phosphate-binding
                     protein, score 81.40, E-value 1.8e-20"
     PFAM_domain     complement(7500..8231)
                     /aSDomain="PBP_like_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF12849.10"
                     /description="PBP superfamily domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6816_0894"
                     /evalue="2.90E-32"
                     /label="SCO6816"
                     /locus_tag="SCO6816"
                     /protein_end="271"
                     /protein_start="27"
                     /score="112.6"
                     /tool="antismash"
                     /translation="GAGKSGALQVSGSTTVAPVAADAAEALKADGLDITVATQGGSAGG
                     ISQLASGQITIALSSKPLSEEDKAANPDTDFVSTQIGADAVGIIVTKQVADAGVKNLTA
                     DQVRDLFEGKIKNWSEVGGPDLDVFVYDKEPGRGTREVLDKYIYGDEKAPPPPESGNFA
                     IVGGNLETRNKLESTPGAVAPLSTSFVEGRDRLAAVTLDGIEASPENIATGKYPMSRPL
                     YLITDGKPEGTAKKFIDYVLSA"
     misc_feature    complement(8217..8240)
                     /gene_synonym="SC1A2.25c"
                     /locus_tag="SCO6816"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     misc_feature    complement(8241..8273)
                     /gene_synonym="SC1A2.25c"
                     /locus_tag="SCO6816"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site"
     gene            complement(8633..8992)
                     /db_xref="GeneID:1102256"
                     /gene_synonym="SC1A2.26c"
                     /locus_tag="SCO6817"
     CDS             complement(8633..8992)
                     /codon_start=1
                     /db_xref="GeneID:1102256"
                     /gene_synonym="SC1A2.26c"
                     /locus_tag="SCO6817"
                     /note="SC1A2.26c, unknown, len: 119 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_630889.1"
                     /transl_table=11
                     /translation="MSPLTPTPDHAPWHRTPALSDCLTQPHIAAAFARDALVRELEADG
                     IEGVLHEPADRSRAVLGLHNPSMTESRVNLRALLPEHAHCTWHFLSGSMHTSEAADGLH
                     LHLAASDTVWLTTTT"
     gene            complement(8989..10524)
                     /db_xref="GeneID:1102257"
                     /gene_synonym="SC1A2.27c."
                     /locus_tag="SCO6818"
     CDS             complement(8989..10524)
                     /EC_number="5.4.2.1"
                     /codon_start=1
                     /db_xref="GeneID:1102257"
                     /gene_synonym="SC1A2.27c."
                     /locus_tag="SCO6818"
                     /note="catalyzes the interconversion of 2-phosphoglycerate
                     and 3-phosphoglycerate"
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="NP_630890.1"
                     /transl_table=11
                     /translation="MSTPEPVLAGPGILLVLDGWGSADAADDNALSLARTPVLDELVAQ
                     HPSTLAEASGEAVGLLPGTVGNSEIGHMVIGAGRPLPYDSLLVQQAIDSGALRSHPRLD
                     AVLNEVAATSGALHLIGLCSDGQIHAHVEHLSELLAAAATHQVERVFIHAITDGRDVAD
                     HTGEAYLTRVAELAAAAGTGQIATVIGRGYAMDKAGDLDLTERAVALVADGRGSPADSA
                     HSAVHSSERGDEWVPASVLTEAGDARVADGDAVLWFNFRSDRIQQFADRLHEHLTASGR
                     TVNMVSLAQYDTRTAIPALVKRADASGGLADELQEAGLRSVRIAETEKFEHVTYYINGR
                     DATVRDGEEHVRITGEGKADYVAHPHMNLDRVTDAVVEAAGRVDVDLVIANLANIDVVG
                     HTGNLAATVTACEATDAAVDQILQAARNSGRWVVAVGDHGNAERMTKQAPDGSVRPYGG
                     HTTNPVPLVIVPNRTDTPAPTLPGTATLADVAPTILHLLGHKPGPAMTGRPLL"
     aSDomain        complement(8992..10488)
                     /aSDomain="TIGR01307"
                     /aSTool="tigrfam"
                     /description="pgm_bpd_ind: phosphoglycerate mutase
                     (2,3-diphosphoglycerate-independent)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6818_0104"
                     /evalue="4.80E-126"
                     /identifier="TIGR01307"
                     /label="SCO6818"
                     /locus_tag="SCO6818"
                     /protein_end="511"
                     /protein_start="12"
                     /score="419.1"
                     /tool="antismash"
                     /translation="ILLVLDGWGSADAADDNALSLARTPVLDELVAQHPSTLAEASGEA
                     VGLLPGTVGNSEIGHMVIGAGRPLPYDSLLVQQAIDSGALRSHPRLDAVLNEVAATSGA
                     LHLIGLCSDGQIHAHVEHLSELLAAAATHQVERVFIHAITDGRDVADHTGEAYLTRVAE
                     LAAAAGTGQIATVIGRGYAMDKAGDLDLTERAVALVADGRGSPADSAHSAVHSSERGDE
                     WVPASVLTEAGDARVADGDAVLWFNFRSDRIQQFADRLHEHLTASGRTVNMVSLAQYDT
                     RTAIPALVKRADASGGLADELQEAGLRSVRIAETEKFEHVTYYINGRDATVRDGEEHVR
                     ITGEGKADYVAHPHMNLDRVTDAVVEAAGRVDVDLVIANLANIDVVGHTGNLAATVTAC
                     EATDAAVDQILQAARNSGRWVVAVGDHGNAERMTKQAPDGSVRPYGGHTTNPVPLVIVP
                     NRTDTPAPTLPGTATLADVAPTILHLLGHKPGPAMTGRPLL"
     PFAM_domain     complement(9025..10488)
                     /aSDomain="Metalloenzyme"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01676.21"
                     /db_xref="GO:0003824"
                     /db_xref="GO:0046872"
                     /description="Metalloenzyme superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6818_0895"
                     /evalue="2.90E-58"
                     /gene_ontologies="GO:0003824: catalytic activity"
                     /gene_ontologies="GO:0046872: metal ion binding"
                     /label="SCO6818"
                     /locus_tag="SCO6818"
                     /protein_end="500"
                     /protein_start="12"
                     /score="197.3"
                     /tool="antismash"
                     /translation="ILLVLDGWGSADAADDNALSLARTPVLDELVAQHPSTLAEASGEA
                     VGLLPGTVGNSEIGHMVIGAGRPLPYDSLLVQQAIDSGALRSHPRLDAVLNEVAATSGA
                     LHLIGLCSDGQIHAHVEHLSELLAAAATHQVERVFIHAITDGRDVADHTGEAYLTRVAE
                     LAAAAGTGQIATVIGRGYAMDKAGDLDLTERAVALVADGRGSPADSAHSAVHSSERGDE
                     WVPASVLTEAGDARVADGDAVLWFNFRSDRIQQFADRLHEHLTASGRTVNMVSLAQYDT
                     RTAIPALVKRADASGGLADELQEAGLRSVRIAETEKFEHVTYYINGRDATVRDGEEHVR
                     ITGEGKADYVAHPHMNLDRVTDAVVEAAGRVDVDLVIANLANIDVVGHTGNLAATVTAC
                     EATDAAVDQILQAARNSGRWVVAVGDHGNAERMTKQAPDGSVRPYGGHTTNPVPLVIVP
                     NRTDTPAPTLPGTATLADVAPTILHLLGHK"
     misc_feature    complement(9070..9429)
                     /gene_synonym="SC1A2.27c."
                     /locus_tag="SCO6818"
                     /note="Pfam match to entry PF01676 Metalloenzyme,
                     Metalloenzyme superfamily, score 69.50, E-value 7e-17"
     gene            complement(10521..11843)
                     /db_xref="GeneID:1102258"
                     /gene_synonym="aroA"
                     /locus_tag="SCO6819"
     CDS             complement(10521..11843)
                     /EC_number="2.5.1.19"
                     /codon_start=1
                     /db_xref="GeneID:1102258"
                     /gene_synonym="aroA"
                     /locus_tag="SCO6819"
                     /note="catalyzes the formation of
                     5-O-(1-carboxyvinyl)-3-phosphoshikimate from
                     phosphoenolpyruvate and 3-phosphoshikimate in tryptophan
                     biosynthesis"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="NP_630891.1"
                     /transl_table=11
                     /translation="MSATPDPRLKAETLTIRTLTGFDETVRVLGSKSYTNRYLAIASLS
                     GQETVIDNALLSDDTVYFSRAIETFGHVTCDIDHATARIRVTPTGRPMRAPSEDIFVGG
                     AGTPLRFLISMAGHADGTTIITGNARMQERPMGDLLKALPALGVDATAVRGNGSPPVRV
                     VGGSFKGGATSISGAVSSQFTSSLIINALRAQTDTEITISDDLVSKPYVEMTLAGLAEM
                     GVSVDRDGYRRFTVPSGQQARGGQVTVEPDASGMSYFLAAAAILQSRVVIPGIGAGSHQ
                     GDVHLVQALERMGCRTEVGDDSITVTGGPLRGIDIDMEAMPDVVPSLAIVAAYAEGTTR
                     ITNIASLRVKECDRIAAVTTELRKMGIDVEEHSDAMYITGGTPHGAVIDTYDDHRIAMT
                     FAIGGLRTEGVVIKDPGCVAKSFPAFWQTLDTLHPDLESTK"
     aSDomain        complement(10545..11768)
                     /aSDomain="TIGR01356"
                     /aSTool="tigrfam"
                     /description="aroA: 3-phosphoshikimate
                     1-carboxyvinyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6819_0105"
                     /evalue="2.00E-125"
                     /identifier="TIGR01356"
                     /label="SCO6819"
                     /locus_tag="SCO6819"
                     /protein_end="433"
                     /protein_start="25"
                     /score="416.8"
                     /tool="antismash"
                     /translation="VRVLGSKSYTNRYLAIASLSGQETVIDNALLSDDTVYFSRAIETF
                     GHVTCDIDHATARIRVTPTGRPMRAPSEDIFVGGAGTPLRFLISMAGHADGTTIITGNA
                     RMQERPMGDLLKALPALGVDATAVRGNGSPPVRVVGGSFKGGATSISGAVSSQFTSSLI
                     INALRAQTDTEITISDDLVSKPYVEMTLAGLAEMGVSVDRDGYRRFTVPSGQQARGGQV
                     TVEPDASGMSYFLAAAAILQSRVVIPGIGAGSHQGDVHLVQALERMGCRTEVGDDSITV
                     TGGPLRGIDIDMEAMPDVVPSLAIVAAYAEGTTRITNIASLRVKECDRIAAVTTELRKM
                     GIDVEEHSDAMYITGGTPHGAVIDTYDDHRIAMTFAIGGLRTEGVVIKDPGCVAKSFPA
                     FWQTLDTLH"
     PFAM_domain     complement(10557..11777)
                     /aSDomain="EPSP_synthase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00275.23"
                     /db_xref="GO:0016765"
                     /description="EPSP synthase (3-phosphoshikimate
                     1-carboxyvinyltransferase)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6819_0896"
                     /evalue="1.20E-112"
                     /gene_ontologies="GO:0016765: transferase activity,
                     transferring alkyl or aryl (other than methyl) groups"
                     /label="SCO6819"
                     /locus_tag="SCO6819"
                     /protein_end="429"
                     /protein_start="22"
                     /score="376.8"
                     /tool="antismash"
                     /translation="DETVRVLGSKSYTNRYLAIASLSGQETVIDNALLSDDTVYFSRAI
                     ETFGHVTCDIDHATARIRVTPTGRPMRAPSEDIFVGGAGTPLRFLISMAGHADGTTIIT
                     GNARMQERPMGDLLKALPALGVDATAVRGNGSPPVRVVGGSFKGGATSISGAVSSQFTS
                     SLIINALRAQTDTEITISDDLVSKPYVEMTLAGLAEMGVSVDRDGYRRFTVPSGQQARG
                     GQVTVEPDASGMSYFLAAAAILQSRVVIPGIGAGSHQGDVHLVQALERMGCRTEVGDDS
                     ITVTGGPLRGIDIDMEAMPDVVPSLAIVAAYAEGTTRITNIASLRVKECDRIAAVTTEL
                     RKMGIDVEEHSDAMYITGGTPHGAVIDTYDDHRIAMTFAIGGLRTEGVVIKDPGCVAKS
                     FPAFWQTL"
     misc_feature    complement(10557..11804)
                     /gene_synonym="aroA"
                     /locus_tag="SCO6819"
                     /note="Pfam match to entry PF00275 EPSP_synthase, EPSP
                     synthase (3-phosphoshikimate 1-carboxyvinyltransferase),
                     score 442.90, E-value 2.7e-129"
     misc_feature    complement(10746..10802)
                     /gene_synonym="aroA"
                     /locus_tag="SCO6819"
                     /note="PS00885 EPSP synthase signature 2."
     regulatory      complement(11849..11855)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(11898..14228)
                     /db_xref="GeneID:1102259"
                     /gene_synonym="SC1A2.29c"
                     /locus_tag="SCO6820"
     CDS             complement(11898..14228)
                     /codon_start=1
                     /db_xref="GeneID:1102259"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134:flavodoxin (Score: 521.4; E-value: 5.3e-158)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC1A2.29c"
                     /locus_tag="SCO6820"
                     /note="SC1A2.29c, possible oxidoreductase, len: 776 aa.
                     Similar to a number of formate dehydrogenases e.g.
                     Escherichia coli SW:FDHF_ECOLI(EMBL:M13563) formate
                     dehydrogenase H (EC 1.2.1.2) (715 aa), fasta scores opt:
                     503 z-score: 564.0 E(): 5.2e-24 29.4% identity in 799 aa
                     overlap. Contains Pfam matches to entries PF00384
                     molybdopterin, Prokaryotic molybdopterin oxidoreductases
                     and PF01568 Molydop_binding, Molydopterin dinucleotide
                     binding domain."
                     /product="oxidoreductase"
                     /protein_id="NP_630892.1"
                     /transl_table=11
                     /translation="MTPDKTVATACQFCNSNCRLNVDLKAGRVLAVRGEDSDPVQQGQV
                     CVKAELMPQLVYNTERLTRPLRRVSGAKGSPHSKFEAVSWEEALHTIAKKFLALRDAGQ
                     AHTIANRTTGRMPRGTGSLVARMFAMLGSPNNTDVGPVCNDAGGNALAMTFGLGNFTNG
                     YGTDGSTGKDDLGSARHYLFLGTNQAETHPVTFDYLLRGRKENNATLTVVDPRLTPTGA
                     AADRWVAPKPHTDLALLLAMLHHIVQEKLYDKAFVKRWVAGFDELRRHLAKHQYTPEWA
                     AKVTGVKADVITKMAVEYAKAKPAAIFCNAGISHQLGAFDTYRVATFLAAVTGNIGQPG
                     GGCNFMHNTWPGDLQLPPLDADLPERREALPVGPDYFAESILTDNPYRLRAVVTQGNPL
                     VSSANTTKVKKAFEQLDFYVYTGLFMEEAAYYADIILPVCSGLEMEGVYMRRDDRAIRW
                     QDQAVDRVGESRPDWEIWVGLAHALAELDSRRPAAEWRAAFPERWMNYRELWDAFVTHT
                     PGVGGMTRARMRQRTEPLRWPCPTEDHPGVSTLYLDHPSWYQAAESLDPANRGKRFLTP
                     SGKVEISTPDLEKKLAVTGHSALPIFYTHPEVTGRNPTLSYSRKFVTNPINPQAVTHPV
                     RLGVPGSDAVHHDFPLMGMTGRPSVVHFAEVTHWTPTGKQLNGIRFIQIHPDTARRSGI
                     ADGDEVTVESPRGSVTGTALLWEGIRADTVFVPNTFGPAQKQGDLFDDPRYEAANTLPD
                     DRFYDNLSGQQAFKCFACRVVKA"
     misc_feature    complement(11919..12278)
                     /gene_synonym="SC1A2.29c"
                     /locus_tag="SCO6820"
                     /note="Pfam match to entry PF01568 Molydop_binding,
                     Molydopterin dinucleotide binding domain, score 54.10,
                     E-value 3e-12"
     PFAM_domain     complement(11925..12269)
                     /aSDomain="Molydop_binding"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01568.24"
                     /db_xref="GO:0016491"
                     /db_xref="GO:0043546"
                     /description="Molydopterin dinucleotide binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6820_0899"
                     /evalue="8.20E-17"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /gene_ontologies="GO:0043546: molybdopterin cofactor
                     binding"
                     /label="SCO6820"
                     /locus_tag="SCO6820"
                     /protein_end="768"
                     /protein_start="653"
                     /score="61.3"
                     /tool="antismash"
                     /translation="MTGRPSVVHFAEVTHWTPTGKQLNGIRFIQIHPDTARRSGIADGD
                     EVTVESPRGSVTGTALLWEGIRADTVFVPNTFGPAQKQGDLFDDPRYEAANTLPDDRFY
                     DNLSGQQAFKC"
     misc_feature    complement(12789..12980)
                     /gene_synonym="SC1A2.29c"
                     /locus_tag="SCO6820"
                     /note="Pfam match to entry PF00384 molybdopterin,
                     Prokaryotic molybdopterin oxidoreductases, score 44.40,
                     E-value 2.8e-13"
     PFAM_domain     complement(12789..14048)
                     /aSDomain="Molybdopterin"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00384.25"
                     /db_xref="GO:0016491"
                     /description="Molybdopterin oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6820_0898"
                     /evalue="1.40E-53"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO6820"
                     /locus_tag="SCO6820"
                     /protein_end="480"
                     /protein_start="60"
                     /score="182.6"
                     /tool="antismash"
                     /translation="RLTRPLRRVSGAKGSPHSKFEAVSWEEALHTIAKKFLALRDAGQA
                     HTIANRTTGRMPRGTGSLVARMFAMLGSPNNTDVGPVCNDAGGNALAMTFGLGNFTNGY
                     GTDGSTGKDDLGSARHYLFLGTNQAETHPVTFDYLLRGRKENNATLTVVDPRLTPTGAA
                     ADRWVAPKPHTDLALLLAMLHHIVQEKLYDKAFVKRWVAGFDELRRHLAKHQYTPEWAA
                     KVTGVKADVITKMAVEYAKAKPAAIFCNAGISHQLGAFDTYRVATFLAAVTGNIGQPGG
                     GCNFMHNTWPGDLQLPPLDADLPERREALPVGPDYFAESILTDNPYRLRAVVTQGNPLV
                     SSANTTKVKKAFEQLDFYVYTGLFMEEAAYYADIILPVCSGLEMEGVYMRRDDRAIRWQ
                     DQAVDRVGESRPDWEIWVGLA"
     PFAM_domain     complement(14055..14216)
                     /aSDomain="Molybdop_Fe4S4"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04879.19"
                     /db_xref="GO:0016491"
                     /description="Molybdopterin oxidoreductase Fe4S4 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6820_0897"
                     /evalue="4.60E-15"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO6820"
                     /locus_tag="SCO6820"
                     /protein_end="58"
                     /protein_start="4"
                     /score="55.5"
                     /tool="antismash"
                     /translation="KTVATACQFCNSNCRLNVDLKAGRVLAVRGEDSDPVQQGQVCVKA
                     ELMPQLVYN"
     gene            complement(14531..15253)
                     /db_xref="GeneID:1102260"
                     /gene_synonym="SC1A2.30c"
                     /locus_tag="SCO6821"
     CDS             complement(14531..15253)
                     /codon_start=1
                     /db_xref="GeneID:1102260"
                     /gene_synonym="SC1A2.30c"
                     /locus_tag="SCO6821"
                     /note="SC1A2.30c, possible transferase, len: 240 aa. Weakly
                     similar to the C-terminal glutamine amide transferase
                     domain of several CTP synthases e.g. Escherichia coli
                     SW:PYRG_ECOLI(EMBL:M12843) CTP synthase (EC 6.3.4.2) (544
                     aa), fasta scores opt: 184 z-score: 227.2 E(): 3e-05 24.4%
                     identity in 225 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_630893.1"
                     /transl_table=11
                     /translation="MSVSARPRLALVGDRGNHDEPSHPKIDAMREQWDLTTEWIPTTDI
                     HDVSVLDGFDGIWVVPGAPYFNQKGVHVAVRHARENGLPFLGTCGGFFSALIEHAQNVL
                     HLPEAAGVDEDPEKLMPLVTPLKCSFRGEKAPLTVMENSRLAGIYGTTEVEEIFHCDYG
                     LTDTFMNAANQGSLRLSAWDSDGAPRALEITGHPFFLGSLFQPELSSAPGSEHKILKAF
                     LAAVSAKADTDALPMPTT"
     PFAM_domain     complement(14585..15157)
                     /aSDomain="GATase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00117.31"
                     /description="Glutamine amidotransferase class-I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6821_0900"
                     /evalue="1.40E-10"
                     /label="SCO6821"
                     /locus_tag="SCO6821"
                     /protein_end="223"
                     /protein_start="32"
                     /score="41.4"
                     /tool="antismash"
                     /translation="WDLTTEWIPTTDIHDVSVLDGFDGIWVVPGAPYFNQKGVHVAVRH
                     ARENGLPFLGTCGGFFSALIEHAQNVLHLPEAAGVDEDPEKLMPLVTPLKCSFRGEKAP
                     LTVMENSRLAGIYGTTEVEEIFHCDYGLTDTFMNAANQGSLRLSAWDSDGAPRALEITG
                     HPFFLGSLFQPELSSAPGSEHKILKAFL"
     gene            15999..17564
                     /db_xref="GeneID:1102261"
                     /gene_synonym="SC1A2.31"
                     /locus_tag="SCO6822"
     CDS             15999..17564
                     /codon_start=1
                     /db_xref="GeneID:1102261"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 381.4; E-value:
                     7.9e-116)"
                     /gene_kind="transport"
                     /gene_synonym="SC1A2.31"
                     /locus_tag="SCO6822"
                     /note="SC1A2.31, possible integral membrane efflux protein,
                     len: 521 aa. Highly similar to many members of the drug
                     resistance translocase family including: Streptomyces
                     virginiae TR:Q9XE01 (EMBL:AB019519) virginiamycin S
                     resistance protein, VarS (518 aa), fasta scores opt: 1230
                     z-score: 1294.4 E():0 40.7% identity in 523 aa overlap and
                     Streptomyces coelicolor TR:Q9Z563 (EMBL:AL035569) integral
                     membrane efflux protein, SC8D9.28C (521 aa), fasta scores
                     opt: 1072 z-score: 1128.8 E():0 37.7% identity in 515 aa
                     overlap. Contains a Prosite hit to PS00216 Sugar transport
                     proteins signature 1 and a Pfam match to entry PF00083
                     sugar_tr, Sugar (and other) transporter. Also contains a
                     possible N-terminal signal sequence and multiple possible
                     membrane spanning hydrophobic domains."
                     /product="integral membrane efflux protein"
                     /protein_id="NP_630894.1"
                     /transl_table=11
                     /translation="MNSSAGHPRRWQILNILCLSLVLIGLDTLILNLALPSIQKDLDAT
                     SSQLQWMVDSYALAFGGLLLMAGGLSDRFGRKRLLSVGLGAFALTSLGAAFASNAEMLI
                     TFRALMGISAALMMPATLAIIKDVFPREEQGKAIGIWSGAAAVGVPLGPLVSGLLLEHF
                     WWGSMFLINVPLAAIALIGGAKLIPESKAEGHPGLDLVGALLSVAGLVAIVYGLVEAPH
                     NGWGDIITLGSLFVGVVLMVAFVLWERKTAHPMLDVGLFLNARYGGGALAIACTSFGLY
                     SGLYLLTQYLQSVLELDPLGAGLRMLAIGTMMVGAPLSAKLVERTGLKATVVVGLLLCA
                     AGLGVLAGLSVDDETQALIGLAVFGLGMGIALPAAVDAILVVSAARQAGAGSAVADVGM
                     QVGGALGIAISGSVIATLYRDDLPQAAQLPGEAGEAVHESLAGASAVAQQLGGDTGRRV
                     LDAAQQSFVGGFTGTLLIAVGVAAVGALAAAFILPRARVADEDGTAQSEAAARSDSADA
                     AATS"
     misc_feature    16035..17396
                     /gene_synonym="SC1A2.31"
                     /locus_tag="SCO6822"
                     /note="Pfam match to entry PF00083 sugar_tr, Sugar (and
                     other) transporter, score -89.50, E-value 0.0011"
     aSDomain        16044..17438
                     /aSDomain="TIGR00711"
                     /aSTool="tigrfam"
                     /description="efflux_EmrB: drug resistance MFS transporter,
                     drug:H+ antiporter-2 (14 Spanner) (DHA2) family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6822_0106"
                     /evalue="6.10E-74"
                     /identifier="TIGR00711"
                     /label="SCO6822"
                     /locus_tag="SCO6822"
                     /protein_end="480"
                     /protein_start="15"
                     /score="247.4"
                     /tool="antismash"
                     /translation="ILCLSLVLIGLDTLILNLALPSIQKDLDATSSQLQWMVDSYALAF
                     GGLLLMAGGLSDRFGRKRLLSVGLGAFALTSLGAAFASNAEMLITFRALMGISAALMMP
                     ATLAIIKDVFPREEQGKAIGIWSGAAAVGVPLGPLVSGLLLEHFWWGSMFLINVPLAAI
                     ALIGGAKLIPESKAEGHPGLDLVGALLSVAGLVAIVYGLVEAPHNGWGDIITLGSLFVG
                     VVLMVAFVLWERKTAHPMLDVGLFLNARYGGGALAIACTSFGLYSGLYLLTQYLQSVLE
                     LDPLGAGLRMLAIGTMMVGAPLSAKLVERTGLKATVVVGLLLCAAGLGVLAGLSVDDET
                     QALIGLAVFGLGMGIALPAAVDAILVVSAARQAGAGSAVADVGMQVGGALGIAISGSVI
                     ATLYRDDLPQAAQLPGEAGEAVHESLAGASAVAQQLGGDTGRRVLDAAQQSFVGGFTGT
                     LLIAVGV"
     PFAM_domain     16047..17216
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07690.19"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6822_0901"
                     /evalue="1.20E-52"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO6822"
                     /locus_tag="SCO6822"
                     /protein_end="406"
                     /protein_start="16"
                     /score="179.2"
                     /tool="antismash"
                     /translation="LCLSLVLIGLDTLILNLALPSIQKDLDATSSQLQWMVDSYALAFG
                     GLLLMAGGLSDRFGRKRLLSVGLGAFALTSLGAAFASNAEMLITFRALMGISAALMMPA
                     TLAIIKDVFPREEQGKAIGIWSGAAAVGVPLGPLVSGLLLEHFWWGSMFLINVPLAAIA
                     LIGGAKLIPESKAEGHPGLDLVGALLSVAGLVAIVYGLVEAPHNGWGDIITLGSLFVGV
                     VLMVAFVLWERKTAHPMLDVGLFLNARYGGGALAIACTSFGLYSGLYLLTQYLQSVLEL
                     DPLGAGLRMLAIGTMMVGAPLSAKLVERTGLKATVVVGLLLCAAGLGVLAGLSVDDETQ
                     ALIGLAVFGLGMGIALPAAVDAILVVSAARQAGAGSAVADVGMQVGGALG"
     misc_feature    16197..16247
                     /gene_synonym="SC1A2.31"
                     /locus_tag="SCO6822"
                     /note="PS00216 Sugar transport proteins signature 1"
     gene            17582..18034
                     /db_xref="GeneID:1102262"
                     /gene_synonym="SC1A2.32"
                     /locus_tag="SCO6823"
     CDS             17582..18034
                     /codon_start=1
                     /db_xref="GeneID:1102262"
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 0; E-value: 14.0)"
                     /gene_kind="regulatory"
                     /gene_synonym="SC1A2.32"
                     /locus_tag="SCO6823"
                     /note="SC1A2.32, possible ArsR-family transcriptional
                     regulator, len: 150 aa. Similar to several including:
                     Sinorhizobium sp. As4 TR:AAD51845 (EMBL:AF178758) ArsR
                     regulatory protein (115 aa), fasta scores opt: 129 z-score:
                     168.5 E(): 0.056 29.1% identity in 103 aa overlap. Contains
                     a Pfam match to entry PF01022 HTH_5, Bacterial regulatory
                     protein, arsR family with a helix-turn-helix motif situated
                     between residues 68..89 (+3.74 SD)."
                     /product="transcription regulator ArsR"
                     /protein_id="NP_630895.1"
                     /transl_table=11
                     /translation="MRRIDSTARPAGEREVAMARPSKLRVAVSDPDQWLSERERAQMLA
                     PKLRALADETRLTLILLIAQRPRTVKELQEATGLSQTLVSHHLAPLREQNLVEAIPKGR
                     SNQYVMCCQTLAEPLRMFASLAAMDPETVAACLQTGAGQPAAAQGA"
     misc_feature    17723..17974
                     /gene_synonym="SC1A2.32"
                     /locus_tag="SCO6823"
                     /note="Pfam match to entry PF01022 HTH_5, Bacterial
                     regulatory protein, arsR family, score 35.80, E-value
                     1e-06"
     PFAM_domain     17738..17875
                     /aSDomain="HTH_5"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01022.23"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory protein, arsR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6823_0902"
                     /evalue="3.10E-13"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO6823"
                     /locus_tag="SCO6823"
                     /protein_end="98"
                     /protein_start="52"
                     /score="49.5"
                     /tool="antismash"
                     /translation="DETRLTLILLIAQRPRTVKELQEATGLSQTLVSHHLAPLREQNLV
                     E"
     stem_loop       18059..18110
                     /note="possible stem loop with 100% matches over 24 bases
                     and a loop region of 4 bases."
     gene            complement(18121..19224)
                     /db_xref="GeneID:1102263"
                     /gene_synonym="SC1A2.33c; SC4A9.01c"
                     /locus_tag="SCO6824"
     CDS             complement(18121..19224)
                     /codon_start=1
                     /db_xref="GeneID:1102263"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 65.5;
                     E-value: 6.8e-20)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC1A2.33c; SC4A9.01c"
                     /locus_tag="SCO6824"
                     /note="SC4A9.01c, possible phosphonopyruvate decarboxylase,
                     partial CDS, len: >32 aa. Highly similar to Streptomyces
                     coelicolor TR:Q9XBE9(EMBL:AL078635) phosphonopyruvate
                     decarboxylase, CZA382.02 (371 aa), fasta scores opt:95
                     z-score: 160.0 E():0.17 51.7% identity in 29 aa overlap.
                     Overlaps and extends into CDS SC1A2.33c on the adjoining
                     cosmid.; SC1A2.33c, possible phosphonopyruvate
                     decarboxylase, partial CDS, len: >366 aa. Highly similar to
                     several including: Streptomyces wedmorensis
                     TR:Q56190(EMBL:AB016934) phosphonopyruvate decarboxylase
                     (384 aa), fasta scores opt: 391 z-score: 431.7 E(): 1.2e-16
                     37.8% identity in 347 aa overlap and Streptomyces
                     coelicolor TR:Q9XBE9(EMBL:AL078635) phosphonopyruvate
                     decarboxylase, CZA382.02 (371 aa), fasta scores opt: 1134
                     z-score: 1240.1 E(): 0 49.2% identity in 366 aa overlap.
                     Contains a Prosite hit to PS00187 Thiamine pyrophosphate
                     enzymes signature."
                     /product="phosphonopyruvate decarboxylase (fragment)"
                     /protein_id="NP_733715.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 6.7e-07, bitscore:
                     27.9, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.7e-17, bitscore:
                     62.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITAQEFCDLLADGGFTFASGVPCSHFGGPIAHLSTEPGRYVPAP
                     NEGSALAVAAGAALGGQRAYVMLQNSGLGNLINPLTSLVMTYQLPILTFASLRGWPDPA
                     TDEPQHAVMGPATHGLLDSVDTPHHTLYAQDGVEEFAAVLEKAEKDLAEQRAPFVLVER
                     GAIGKAAAANSPHTEGLPAAEAIRLVTSAAPQAAVVATTGFTGRDTFAVADTPSTFYMQ
                     GSMGHASSIGLGVALTQPERTVVVLDGDGALLMHLGALSMIGSEAPANLIHVVLDNRVH
                     ESTGGQATTSATTSFPEMAKAAGYADAVVCDREEDVRAAMLRAQAAPGPHLICIKTLPR
                     TGAIPPRATNALSTLDIRDRFQNDLRQ"
     aSDomain        complement(18139..19182)
                     /aSDomain="TIGR03297"
                     /aSTool="tigrfam"
                     /description="Ppyr-DeCO2ase: phosphonopyruvate
                     decarboxylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6824_0107"
                     /evalue="7.10E-106"
                     /identifier="TIGR03297"
                     /label="SCO6824"
                     /locus_tag="SCO6824"
                     /protein_end="362"
                     /protein_start="14"
                     /score="352.2"
                     /tool="antismash"
                     /translation="GFTFASGVPCSHFGGPIAHLSTEPGRYVPAPNEGSALAVAAGAAL
                     GGQRAYVMLQNSGLGNLINPLTSLVMTYQLPILTFASLRGWPDPATDEPQHAVMGPATH
                     GLLDSVDTPHHTLYAQDGVEEFAAVLEKAEKDLAEQRAPFVLVERGAIGKAAAANSPHT
                     EGLPAAEAIRLVTSAAPQAAVVATTGFTGRDTFAVADTPSTFYMQGSMGHASSIGLGVA
                     LTQPERTVVVLDGDGALLMHLGALSMIGSEAPANLIHVVLDNRVHESTGGQATTSATTS
                     FPEMAKAAGYADAVVCDREEDVRAAMLRAQAAPGPHLICIKTLPRTGAIPPRATNALST
                     LDIRDRFQ"
     PFAM_domain     complement(18226..18576)
                     /aSDomain="TPP_enzyme_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02775.24"
                     /db_xref="GO:0003824"
                     /db_xref="GO:0030976"
                     /description="Thiamine pyrophosphate enzyme, C-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6824_0904"
                     /evalue="4.20E-17"
                     /gene_ontologies="GO:0003824: catalytic activity"
                     /gene_ontologies="GO:0030976: thiamine pyrophosphate
                     binding"
                     /label="SCO6824"
                     /locus_tag="SCO6824"
                     /protein_end="333"
                     /protein_start="216"
                     /score="62.5"
                     /tool="antismash"
                     /translation="STFYMQGSMGHASSIGLGVALTQPERTVVVLDGDGALLMHLGALS
                     MIGSEAPANLIHVVLDNRVHESTGGQATTSATTSFPEMAKAAGYADAVVCDREEDVRAA
                     MLRAQAAPGPHLI"
     misc_feature    complement(18469..18528)
                     /gene_synonym="SC1A2.33c; SC4A9.01c"
                     /locus_tag="SCO6824"
                     /note="PS00187 Thiamine pyrophosphate enzymes signature"
     PFAM_domain     complement(18928..19215)
                     /aSDomain="TPP_enzyme_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02776.21"
                     /db_xref="GO:0030976"
                     /description="Thiamine pyrophosphate enzyme, N-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6824_0903"
                     /evalue="1.70E-06"
                     /gene_ontologies="GO:0030976: thiamine pyrophosphate
                     binding"
                     /label="SCO6824"
                     /locus_tag="SCO6824"
                     /protein_end="99"
                     /protein_start="3"
                     /score="27.9"
                     /tool="antismash"
                     /translation="AQEFCDLLADGGFTFASGVPCSHFGGPIAHLSTEPGRYVPAPNEG
                     SALAVAAGAALGGQRAYVMLQNSGLGNLINPLTSLVMTYQLPILTFASLRG"
     misc_feature    19127..19222
                     /note="480 (+1) 1 96 St4A9"
     gene            complement(19221..19916)
                     /db_xref="GeneID:1102264"
                     /gene_synonym="SC4A9.02c"
                     /locus_tag="SCO6825"
     CDS             complement(19221..19916)
                     /codon_start=1
                     /db_xref="GeneID:1102264"
                     /gene_functions="other (smcogs) SMCOG1188:hypothetical
                     protein (Score: 172.4; E-value: 9.8e-53)"
                     /gene_kind="other"
                     /gene_synonym="SC4A9.02c"
                     /locus_tag="SCO6825"
                     /note="SC4A9.02c, possible integral membrane protein, len:
                     231 aa. Highly to several proteins of undefined function
                     including Escherichia coli SW:DEDA_ECOLI (EMBL:M68934) DedA
                     hypothetical protein found in the hisT-purF region (219
                     aa), fasta scores opt: 550 z-score: 642.2 E(): 2.3e-28
                     43.8% identity in 185 aa overlap and Streptomyces
                     coelicolor TR:Q9X8J1 (EMBL:AL049841) possible membrane
                     protein, SCE9.18c (303 aa), fasta scores opt: 812 z-score:
                     940.8 E():0 53.7% identity in 227 aa overlap. Contains
                     multiple possible membrane spanning hydrophobic domains and
                     a Pfam match to entry PF00597 DedA, DedA family."
                     /product="hypothetical protein"
                     /protein_id="NP_630896.1"
                     /transl_table=11
                     /translation="MQNLASSPLLDAEALISGFGLLGIMATVFAESGLIVCFFLPGDSL
                     LFTAGLLVANDQFLHQPLWLVMLAIAAAAVLGDQFGYAFGRKVGGALFRRPNSRFFKQE
                     NAERAQQFMLKHGPKALVMARFIPVFRTFIPITAGIGRMTYRTFFLFNVIGAVLWSVSL
                     TLVGYYLGQVAFVRDNIEGIVIGIVLISGIPIIIEGIKMRRRARSAPAAGQETPITPST
                     TPETELPRP"
     misc_feature    complement(19359..19853)
                     /gene_synonym="SC4A9.02c"
                     /locus_tag="SCO6825"
                     /note="Pfam match to entry PF00597 DedA, DedA family, score
                     93.90, E-value 3.1e-24"
     PFAM_domain     complement(19413..19799)
                     /aSDomain="SNARE_assoc"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF09335.14"
                     /description="SNARE associated Golgi protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6825_0905"
                     /evalue="2.70E-23"
                     /label="SCO6825"
                     /locus_tag="SCO6825"
                     /protein_end="168"
                     /protein_start="39"
                     /score="82.8"
                     /tool="antismash"
                     /translation="LPGDSLLFTAGLLVANDQFLHQPLWLVMLAIAAAAVLGDQFGYAF
                     GRKVGGALFRRPNSRFFKQENAERAQQFMLKHGPKALVMARFIPVFRTFIPITAGIGRM
                     TYRTFFLFNVIGAVLWSVSLTLVGY"
     gene            complement(20001..21041)
                     /db_xref="GeneID:1102265"
                     /gene_synonym="SC4A9.03c"
                     /locus_tag="SCO6826"
     CDS             complement(20001..21041)
                     /codon_start=1
                     /db_xref="GeneID:1102265"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 99.1; E-value: 4.2e-30)"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SC4A9.03c"
                     /locus_tag="SCO6826"
                     /note="SC4A9.03c, unknown, len: 346 aa. Similar to a
                     protein of undefined function encoded within the
                     Streptomyces peucetius daunorubicin-doxorubicin polyketide
                     synthase gene cluster: TR:Q54816 (EMBL:L35560) DpsC (353
                     aa), opt: 662 z-score: 779.9 E(): 0 36.0% identity in 344
                     aa overlap. Also similar to Streptomyces sp. TR:Q55225
                     (EMBL:L34880) OrfC, a beta-keto acyl synthase III homologue
                     (352 aa), fasta scores opt: 599 z-score: 706.2 E(): 6.3e-32
                     33.4% identity in 341 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_630897.1"
                     /sec_met_domain="ksIII (E-value: 5.4e-73, bitscore: 244.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTTDIRIAGLGTYIPEIVDARKAVALGLYDADDYEFYGWTGAAV
                     ADDMPAPDMAVAAARQAMERSALHPHDIDFHIHACGHEQGPEGWSPQHYILRHLTDRDV
                     PSFRVWQACSGLIGSLELAACYLKAVPERSAALLTGADNVGTPNFNRWAFGIQNGVLGD
                     GGSAILLSKSEGFASLLSINTGSTAEVEEQYRGTEPLFPPSLTVGRGMDFKERLAAAGG
                     LEETVAEVVRRQGELRTEIALRTLAEAGLEPGDVTRVCHVFTGQESYLKVILDPMGLSP
                     DQGLLDFGRNLGHMTVNDQIVGLTHLVETGQVGPGDHVLIVAHGGGVSITCAVVRIDQR
                     PDWAAG"
     PFAM_domain     complement(20031..20306)
                     /aSDomain="ACP_syn_III_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08541.13"
                     /description="3-Oxoacyl-[acyl-carrier-protein (ACP)]
                     synthase III C terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6826_0906"
                     /evalue="4.90E-16"
                     /label="SCO6826"
                     /locus_tag="SCO6826"
                     /protein_end="337"
                     /protein_start="245"
                     /score="58.8"
                     /tool="antismash"
                     /translation="LAEAGLEPGDVTRVCHVFTGQESYLKVILDPMGLSPDQGLLDFGR
                     NLGHMTVNDQIVGLTHLVETGQVGPGDHVLIVAHGGGVSITCAVVRI"
     gene            complement(21068..28144)
                     /db_xref="GeneID:1102266"
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
     CDS             complement(21068..28144)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (15-440). E-value:
                     2e-175. Score: 575.6. Matches aSDomain:
                     nrpspksdomains_SCO6827_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (548-845). E-value: 1.1e-105.
                     Score: 345.1. Matches aSDomain:
                     nrpspksdomains_SCO6827_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (917-1083). E-value: 1.7e-30.
                     Score: 98.4. Matches aSDomain:
                     nrpspksdomains_SCO6827_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1470-1781). E-value: 2.9e-105.
                     Score: 343.7. Matches aSDomain:
                     nrpspksdomains_SCO6827_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1803-1994). E-value: 1.5e-59.
                     Score: 192.8. Matches aSDomain:
                     nrpspksdomains_SCO6827_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2129-2210). E-value: 2.7e-19.
                     Score: 61.2. Matches aSDomain:
                     nrpspksdomains_SCO6827_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_PP (2269-2351). E-value: 1e-19.
                     Score: 62.5. Matches aSDomain:
                     nrpspksdomains_SCO6827_PKS_PP.2"
                     /codon_start=1
                     /db_xref="GeneID:1102266"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 99; E-value:
                     4e-30)"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="SC4A9.04c, polyketide synthase, len: 2358 aa. Highly
                     similar to many including: Stigmatella aurantiaca
                     TR:AAF19813(EMBL:AF188287) polyketide synthase, MtAE, found
                     within the Myxothiazol biosynthetic gene cluster (1947 aa),
                     fasta scores opt: 2671 z-score: 2436.5 E():0 35.8% identity
                     in 1770 aa overlap and Mycobacterium tuberculosis
                     SW:PPSA_MYCTU(EMBL:Z74697) phenolpthiocerol synthesis
                     polyketide synthase gene, PpsA (1876 aa), fasta scores opt:
                     2221 z-score: 2025.5 E(): 0 33.6% identity in 1761 aa
                     overlap. Contains Prosite hits to PS00606 Beta-ketoacyl
                     synthases active site and 2xPS00012 Phosphopantetheine
                     attachment site. Also contains Pfam matches to entries
                     PF00109 ketoacyl-synt, Beta-ketoacyl synthase, PF00698
                     Acyl_transf, Acyl transferase domain, PF00107 adh_zinc,
                     Zinc-binding dehydrogenases and 2xPF00550 pp-binding,
                     Phosphopantetheine attachment site. The 72 amino acids,
                     2139..2210, are perfectly repeated between residues
                     2280..2351 in the C-terminus of this protein."
                     /product="polyketide synthase"
                     /protein_id="NP_630898.1"
                     /sec_met_domain="hyb_KS (E-value: 1e-173, bitscore: 577.0,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.6e-103, bitscore:
                     345.1, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 3e-08, bitscore: 32.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8e-11, bitscore:
                     40.9, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.5e-51, bitscore:
                     173.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.6e-10, bitscore:
                     40.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHDSTRAAGTASEPIAIIGMAGRFADATSLEQLWDMLLQGRDAI
                     TDIPPDRYDVDAVYDPTPRTPGRTVSRWGGLLHDIDAFDAEFFGISPREADRMDPQQRL
                     LLEVAYEALEDAGQPLPRIAGTDTGVFIGQLGGDYWHLQYDDRDQLDLYAMTGAAARAI
                     TSGRLSYAFDLRGPSFTVDTACSSALVAVHNAVQAIRLGECPLAIAGGVNLVLLPEEGV
                     VYSGAGMLASDGRCKFADASGDGFVRSDGIGAVILKPLSAALADGDRIRAVIRGSAVGN
                     DGQSSGYLVTPAVEGQRDVLRRAYANAAVDPADIDYIEAHGTGTSVGDPVELQALADIV
                     GARASDDRCLVGSVKTNIGHAEAAAGIAGLIKAVLCLENKTIPPNLHLKNPNPTVDWAN
                     LPLAVPTHATPLPQRDRPAIAGVSSFGFSGTNAHLVLEAAPEPRTTARDTAPDARSELL
                     VLSALSPEALSEAARSMADHLEGPGARQKLRDIAHSAALRRTPHDARLALPVQSHAEAA
                     AALRGFADGDNEPGLSFSDYTDSEATPRVAFVFPGQGSQWPGMGRELLDSEPVFHQAMR
                     DCDDAIRTENGWSVIELLRSADEERLKELDVIQPTLWAIEIALAQLWRSWGIEPDVVIG
                     HSMGESAAAYIAGALSLSDAAAVICRRSRLAKRLSGRGTMAWVALPADEAAAALVGHED
                     TVAVAAINSPTSTLLSGDGEALDQVLAGLDARSVDNRRVNVDFASHCPQMDALQEDLLS
                     ELSHLTPRAGTIPLHSTLLNEVIDGSGMNAEYWVRNIRQPVDFVGAVKGQLDLGDTVFV
                     EVSPHPLLVSGIRETSRMATSADTTAVGSLRRHADERGSLLTSAAALHTAGARLDLDKL
                     TADGSYVALPTYPWQRTRHWISPGPARPAAAPAAPAEPASGREQATHPLLGKPSPTEDA
                     TRTWQGPLRLADHPYLRDHCIQDTIILPGTAHLELVSAAARTELGSGALSVSEVRYHRA
                     LFLDEDGPAPEVQVTVTPRPDSSLHCRILSRESADDDWALHTEATARAVEGDTPRAGES
                     LQSIRARLPQHQDADDFYAWNAARGNQWNGTFQGITELWRADGEVLAQLTCPAALLDGL
                     AHHHFHPALLDASGHAMAAARELTAPGDEGVFVLGGIDEVRFYQQPPASLFSHAKLLPS
                     PREDSFAADIDIRADDGRLIAQMRGLRLQYLAGHAPALLTPPTEDPVTPSRTSGSPAAP
                     ASDDRDTWLHTLSWDEAPLPAPATGATDPDGFWLLLTDSGPTGRALARELNGRDQRVVA
                     VTAGAGQLAGGGDRYRIDPTKEEHYREVLTDVARYGACRGIIHLWALDAQTGLDATPTE
                     IHRTQVLAAHSVLHLTRALEKEPLGHPPLWLVTQLAQATGTGERVRHPFQAMSWGLGRT
                     LAAEAPALNPRLVDLDRSPASVPALAEQLLHPDQENQVAWRNGRRLAARLRPAAAATPP
                     PQALSLPAPGVIDDLQLTAVPSRGLAADEVRIQVSHAGVNYRDVLLSLGMYPGQDDRPP
                     VMGWECAGTVTETGSGVTDVAVGDQIIAFAEGALASEVVTRACLTAPKPARLTAAEAAT
                     LPAAYLTAYHALHDMARLERDQKILIHTATGGTGRAALNVARWKGARVFATAGSDAKRQ
                     LLTELGVEQVADSRSLAFADTFKPAVAEGFDVICNTLAGDAIEANLSLMAPYGHYLELS
                     KRDILDNNPLPLGAFARNLSFHAIDVVHMIQHAPERAGRVLRAAATLVDEGALEALPHT
                     VYPVEKAADAFRLIAQARHTGKVVLSFGQSSVTAGGPRGRSVTVHADGTYLVTGGAGGI
                     GGQLALWLADQGARHLLLTGRSALPEQDAVVSETHPQATAVAVLRQLRERGVNVTYKAV
                     DVADAHAMQATLESRRRAGMPPVRGVFHAAGVIDYTLLSDMSGAEMDRVLAAKVSGAWN
                     LHRLLREESVEAFVLFSSGSALLSSPMLGGYAAGNAFLDALAHHRHAQGLSGTVVNWGF
                     WDSVGMVARKEQEEERTLLPHGMTSFSPDDGLSVLGRILAEGRLHTAVLPADWRAWARA
                     YPSAAAAPLVQHLTNRDQSADPTPGPEQQNTEPRPSSQVTEPDTSSRVASAPAAAPAAS
                     AAVAEPPATDRIAPQATAPAQAAPSTELLDFLKQEVAVVMGLRPERVNINRPLNRLGMD
                     SLMAVELRNRVERRYQVKLPMVQLLKDGTITTVAQALANELEPVEEESDTKADDSATPV
                     AAMGSTPPVAEITSAEASRESRAPAAAEPSLPDARASQAPEAAQAPPTDELLDFLKQEV
                     AVVMGLRPERVNINRPLNRLGMDSLMAVELRNRVERRYQVKLPMVQLLKDGTITTVAQA
                     LANELNSADASA"
     repeat_region   complement(21092..21307)
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="duplicated sequence which is 99.52% identical to
                     repeat region complement (2389..2601)."
     aSDomain        complement(21092..21337)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO6827_PKS_PP.2"
                     /evalue="1.00E-19"
                     /label="SCO6827_PKS_PP.2"
                     /locus_tag="SCO6827"
                     /protein_end="2351"
                     /protein_start="2269"
                     /score="62.5"
                     /tool="antismash"
                     /translation="AAQAPPTDELLDFLKQEVAVVMGLRPERVNINRPLNRLGMDSLMA
                     VELRNRVERRYQVKLPMVQLLKDGTITTVAQALANEL"
     PFAM_domain     complement(21104..21301)
                     /aSDomain="PP-binding"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00550.28"
                     /description="Phosphopantetheine attachment site"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6827_0916"
                     /evalue="1.40E-11"
                     /label="SCO6827"
                     /locus_tag="SCO6827"
                     /protein_end="2347"
                     /protein_start="2281"
                     /score="44.6"
                     /tool="antismash"
                     /translation="FLKQEVAVVMGLRPERVNINRPLNRLGMDSLMAVELRNRVERRYQ
                     VKLPMVQLLKDGTITTVAQAL"
     misc_feature    complement(21104..21304)
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="Pfam match to entry PF00550 pp-binding,
                     Phosphopantetheine attachment site, score 49.70, E-value
                     4.1e-12"
     misc_feature    complement(21182..21229)
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="PS00012 Phosphopantetheine attachment site."
     repeat_region   complement(21515..21730)
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="duplicated sequence which is 99.52% identical to
                     repeat region complement (1966..2178)."
     aSDomain        complement(21515..21757)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO6827_PKS_PP.1"
                     /evalue="2.70E-19"
                     /label="SCO6827_PKS_PP.1"
                     /locus_tag="SCO6827"
                     /protein_end="2210"
                     /protein_start="2129"
                     /score="61.2"
                     /tool="antismash"
                     /translation="AQAAPSTELLDFLKQEVAVVMGLRPERVNINRPLNRLGMDSLMAV
                     ELRNRVERRYQVKLPMVQLLKDGTITTVAQALANEL"
     aSModule        complement(21515..28099)
                     /complete
                     /domains="nrpspksdomains_SCO6827_PKS_KS.1"
                     /domains="nrpspksdomains_SCO6827_PKS_AT.1"
                     /domains="nrpspksdomains_SCO6827_PKS_DH.1"
                     /domains="nrpspksdomains_SCO6827_PKS_ER.1"
                     /domains="nrpspksdomains_SCO6827_PKS_KR.1"
                     /domains="nrpspksdomains_SCO6827_PKS_PP.1"
                     /locus_tags="SCO6827"
                     /monomer_pairings="mmal -> Me-redmal"
                     /tool="antismash"
                     /type="pks"
     PFAM_domain     complement(21527..21724)
                     /aSDomain="PP-binding"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00550.28"
                     /description="Phosphopantetheine attachment site"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6827_0915"
                     /evalue="1.40E-11"
                     /label="SCO6827"
                     /locus_tag="SCO6827"
                     /protein_end="2206"
                     /protein_start="2140"
                     /score="44.6"
                     /tool="antismash"
                     /translation="FLKQEVAVVMGLRPERVNINRPLNRLGMDSLMAVELRNRVERRYQ
                     VKLPMVQLLKDGTITTVAQAL"
     misc_feature    complement(21527..21727)
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="Pfam match to entry PF00550 pp-binding,
                     Phosphopantetheine attachment site, score 49.70, E-value
                     4.1e-12"
     misc_feature    complement(21605..21652)
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="PS00012 Phosphopantetheine attachment site"
     aSDomain        complement(22163..22735)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO6827_PKS_KR.1"
                     /evalue="1.50E-59"
                     /label="SCO6827_PKS_KR.1"
                     /locus_tag="SCO6827"
                     /protein_end="1994"
                     /protein_start="1803"
                     /score="192.8"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTYLVTGGAGGIGGQLALWLADQGARHLLLTGRSALPEQDAVVSE
                     THPQATAVAVLRQLRERGVNVTYKAVDVADAHAMQATLESRRRAGMPPVRGVFHAAGVI
                     DYTLLSDMSGAEMDRVLAAKVSGAWNLHRLLREESVEAFVLFSSGSALLSSPMLGGYAA
                     GNAFLDALAHHRHAQGLSGTVVNWGFWD"
     PFAM_domain     complement(22163..22735)
                     /aSDomain="KR"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08659.13"
                     /description="KR domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6827_0914"
                     /evalue="3.30E-63"
                     /label="SCO6827"
                     /locus_tag="SCO6827"
                     /protein_end="1994"
                     /protein_start="1803"
                     /score="212.9"
                     /tool="antismash"
                     /translation="GTYLVTGGAGGIGGQLALWLADQGARHLLLTGRSALPEQDAVVSE
                     THPQATAVAVLRQLRERGVNVTYKAVDVADAHAMQATLESRRRAGMPPVRGVFHAAGVI
                     DYTLLSDMSGAEMDRVLAAKVSGAWNLHRLLREESVEAFVLFSSGSALLSSPMLGGYAA
                     GNAFLDALAHHRHAQGLSGTVVNWGFWD"
     CDS_motif       complement(22208..22312)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0015"
                     /evalue="2.60E-15"
                     /label="PKSI-KR_m4"
                     /locus_tag="SCO6827"
                     /protein_end="1979"
                     /protein_start="1944"
                     /score="48.9"
                     /tool="antismash"
                     /translation="AFVLFSSGSALLSSPMLGGYAAGNAFLDALAHHRH"
     CDS_motif       complement(22634..22732)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0014"
                     /evalue="7.60E-16"
                     /label="PKSI-KR_m1"
                     /locus_tag="SCO6827"
                     /protein_end="1837"
                     /protein_start="1804"
                     /score="50.6"
                     /tool="antismash"
                     /translation="TYLVTGGAGGIGGQLALWLADQGARHLLLTGRS"
     misc_feature    complement(22799..23743)
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases, score -17.90, E-value 8.5e-09"
     CDS_motif       complement(22802..22849)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0013"
                     /evalue="1.80E-05"
                     /label="PKSI-ER_m9"
                     /locus_tag="SCO6827"
                     /protein_end="1781"
                     /protein_start="1765"
                     /score="17.6"
                     /tool="antismash"
                     /translation="AFRLIAQARHTGKVVL"
     PFAM_domain     complement(22802..23218)
                     /aSDomain="ADH_zinc_N_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13602.9"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6827_0913"
                     /evalue="4.10E-20"
                     /label="SCO6827"
                     /locus_tag="SCO6827"
                     /protein_end="1781"
                     /protein_start="1642"
                     /score="73.3"
                     /tool="antismash"
                     /translation="LGVEQVADSRSLAFADTFKPAVAEGFDVICNTLAGDAIEANLSLM
                     APYGHYLELSKRDILDNNPLPLGAFARNLSFHAIDVVHMIQHAPERAGRVLRAAATLVD
                     EGALEALPHTVYPVEKAADAFRLIAQARHTGKVVL"
     aSDomain        complement(22802..23734)
                     /ASF="ER domain putatively catalyzing 2S-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO6827_PKS_ER.1"
                     /evalue="2.90E-105"
                     /label="SCO6827_PKS_ER.1"
                     /locus_tag="SCO6827"
                     /protein_end="1781"
                     /protein_start="1470"
                     /score="343.7"
                     /tool="antismash"
                     /translation="GVIDDLQLTAVPSRGLAADEVRIQVSHAGVNYRDVLLSLGMYPGQ
                     DDRPPVMGWECAGTVTETGSGVTDVAVGDQIIAFAEGALASEVVTRACLTAPKPARLTA
                     AEAATLPAAYLTAYHALHDMARLERDQKILIHTATGGTGRAALNVARWKGARVFATAGS
                     DAKRQLLTELGVEQVADSRSLAFADTFKPAVAEGFDVICNTLAGDAIEANLSLMAPYGH
                     YLELSKRDILDNNPLPLGAFARNLSFHAIDVVHMIQHAPERAGRVLRAAATLVDEGALE
                     ALPHTVYPVEKAADAFRLIAQARHTGKVVL"
     CDS_motif       complement(23225..23275)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0012"
                     /evalue="8.50E-07"
                     /label="PKSI-ER_m6"
                     /locus_tag="SCO6827"
                     /protein_end="1640"
                     /protein_start="1623"
                     /score="21.4"
                     /tool="antismash"
                     /translation="GARVFATAGSDAKRQLL"
     CDS_motif       complement(23285..23347)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0011"
                     /evalue="2.80E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="SCO6827"
                     /protein_end="1620"
                     /protein_start="1599"
                     /score="23.0"
                     /tool="antismash"
                     /translation="DQKILIHTATGGTGRAALNVA"
     CDS_motif       complement(23372..23416)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0010"
                     /evalue="2.90E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="SCO6827"
                     /protein_end="1591"
                     /protein_start="1576"
                     /score="14.3"
                     /tool="antismash"
                     /translation="AATLPAAYLTAYHAL"
     PFAM_domain     complement(23501..23680)
                     /aSDomain="ADH_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08240.15"
                     /description="Alcohol dehydrogenase GroES-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6827_0912"
                     /evalue="7.60E-08"
                     /label="SCO6827"
                     /locus_tag="SCO6827"
                     /protein_end="1548"
                     /protein_start="1488"
                     /score="32.3"
                     /tool="antismash"
                     /translation="DEVRIQVSHAGVNYRDVLLSLGMYPGQDDRPPVMGWECAGTVTET
                     GSGVTDVAVGDQIIA"
     CDS_motif       complement(23543..23581)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0009"
                     /evalue="5.60E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="SCO6827"
                     /protein_end="1534"
                     /protein_start="1521"
                     /score="9.8"
                     /tool="antismash"
                     /translation="MGWECAGTVTETG"
     PFAM_domain     complement(24542..25393)
                     /aSDomain="PS-DH"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF14765.9"
                     /description="Polyketide synthase dehydratase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6827_0911"
                     /evalue="2.40E-68"
                     /label="SCO6827"
                     /locus_tag="SCO6827"
                     /protein_end="1201"
                     /protein_start="917"
                     /score="230.7"
                     /tool="antismash"
                     /translation="HPLLGKPSPTEDATRTWQGPLRLADHPYLRDHCIQDTIILPGTAH
                     LELVSAAARTELGSGALSVSEVRYHRALFLDEDGPAPEVQVTVTPRPDSSLHCRILSRE
                     SADDDWALHTEATARAVEGDTPRAGESLQSIRARLPQHQDADDFYAWNAARGNQWNGTF
                     QGITELWRADGEVLAQLTCPAALLDGLAHHHFHPALLDASGHAMAAARELTAPGDEGVF
                     VLGGIDEVRFYQQPPASLFSHAKLLPSPREDSFAADIDIRADDGRLIAQMRGLRLQYLA
                     GHA"
     aSDomain        complement(24896..25393)
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO6827_PKS_DH.1"
                     /evalue="1.70E-30"
                     /label="SCO6827_PKS_DH.1"
                     /locus_tag="SCO6827"
                     /protein_end="1083"
                     /protein_start="917"
                     /score="98.4"
                     /tool="antismash"
                     /translation="HPLLGKPSPTEDATRTWQGPLRLADHPYLRDHCIQDTIILPGTAH
                     LELVSAAARTELGSGALSVSEVRYHRALFLDEDGPAPEVQVTVTPRPDSSLHCRILSRE
                     SADDDWALHTEATARAVEGDTPRAGESLQSIRARLPQHQDADDFYAWNAARGNQWNGTF
                     QGI"
     CDS_motif       complement(25235..25312)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0008"
                     /evalue="2.30E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="SCO6827"
                     /protein_end="970"
                     /protein_start="944"
                     /score="29.7"
                     /tool="antismash"
                     /translation="YLRDHCIQDTIILPGTAHLELVSAAA"
     misc_feature    complement(25547..26509)
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="Pfam match to entry PF00698 Acyl_transf, Acyl
                     transferase domain, score 395.00, E-value 7.3e-115"
     PFAM_domain     complement(25550..26503)
                     /aSDomain="Acyl_transf_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00698.24"
                     /description="Acyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6827_0910"
                     /evalue="4.40E-86"
                     /label="SCO6827"
                     /locus_tag="SCO6827"
                     /protein_end="865"
                     /protein_start="547"
                     /score="289.4"
                     /tool="antismash"
                     /translation="FVFPGQGSQWPGMGRELLDSEPVFHQAMRDCDDAIRTENGWSVIE
                     LLRSADEERLKELDVIQPTLWAIEIALAQLWRSWGIEPDVVIGHSMGESAAAYIAGALS
                     LSDAAAVICRRSRLAKRLSGRGTMAWVALPADEAAAALVGHEDTVAVAAINSPTSTLLS
                     GDGEALDQVLAGLDARSVDNRRVNVDFASHCPQMDALQEDLLSELSHLTPRAGTIPLHS
                     TLLNEVIDGSGMNAEYWVRNIRQPVDFVGAVKGQLDLGDTVFVEVSPHPLLVSGIRETS
                     RMATSADTTAVGSLRRHADERGSLLTSAAALHTAGAR"
     aSDomain        complement(25610..26500)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO6827_PKS_AT.1"
                     /evalue="1.10E-105"
                     /label="SCO6827_PKS_AT.1"
                     /locus_tag="SCO6827"
                     /protein_end="845"
                     /protein_start="548"
                     /score="345.1"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWPGMGRELLDSEPVFHQAMRDCDDAIRTENGWSVIEL
                     LRSADEERLKELDVIQPTLWAIEIALAQLWRSWGIEPDVVIGHSMGESAAAYIAGALSL
                     SDAAAVICRRSRLAKRLSGRGTMAWVALPADEAAAALVGHEDTVAVAAINSPTSTLLSG
                     DGEALDQVLAGLDARSVDNRRVNVDFASHCPQMDALQEDLLSELSHLTPRAGTIPLHST
                     LLNEVIDGSGMNAEYWVRNIRQPVDFVGAVKGQLDLGDTVFVEVSPHPLLVSGIRETSR
                     MATSADTTAVGSLRRH"
     CDS_motif       complement(25757..25804)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0007"
                     /evalue="6.80E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="SCO6827"
                     /protein_end="796"
                     /protein_start="780"
                     /score="12.2"
                     /tool="antismash"
                     /translation="MNAEYWVRNIRQPVDF"
     CDS_motif       complement(26156..26266)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0006"
                     /evalue="1.10E-17"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="SCO6827"
                     /protein_end="663"
                     /protein_start="626"
                     /score="55.8"
                     /tool="antismash"
                     /translation="GIEPDVVIGHSMGESAAAYIAGALSLSDAAAVICRRS"
     CDS_motif       complement(26270..26338)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0005"
                     /evalue="1.70E-07"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="SCO6827"
                     /protein_end="625"
                     /protein_start="602"
                     /score="23.8"
                     /tool="antismash"
                     /translation="KELDVIQPTLWAIEIALAQLWRS"
     CDS_motif       complement(26450..26503)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0004"
                     /evalue="2.00E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="SCO6827"
                     /protein_end="565"
                     /protein_start="547"
                     /score="29.1"
                     /tool="antismash"
                     /translation="FVFPGQGSQWPGMGRELL"
     PFAM_domain     complement(26651..26974)
                     /aSDomain="KAsynt_C_assoc"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF16197.8"
                     /description="Ketoacyl-synthetase C-terminal extension"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6827_0909"
                     /evalue="6.30E-18"
                     /label="SCO6827"
                     /locus_tag="SCO6827"
                     /protein_end="498"
                     /protein_start="390"
                     /score="65.4"
                     /tool="antismash"
                     /translation="PNPTVDWANLPLAVPTHATPLPQRDRPAIAGVSSFGFSGTNAHLV
                     LEAAPEPRTTARDTAPDARSELLVLSALSPEALSEAARSMADHLEGPGARQKLRDIAHS
                     AALR"
     misc_feature    complement(26825..28099)
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="Pfam match to entry PF00109 ketoacyl-synt,
                     Beta-ketoacyl synthase, score 629.70, E-value 1.6e-185"
     aSDomain        complement(26825..28099)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO6827_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="2.00E-175"
                     /label="SCO6827_PKS_KS.1"
                     /locus_tag="SCO6827"
                     /protein_end="440"
                     /protein_start="15"
                     /score="575.6"
                     /tool="antismash"
                     /translation="IAIIGMAGRFADATSLEQLWDMLLQGRDAITDIPPDRYDVDAVYD
                     PTPRTPGRTVSRWGGLLHDIDAFDAEFFGISPREADRMDPQQRLLLEVAYEALEDAGQP
                     LPRIAGTDTGVFIGQLGGDYWHLQYDDRDQLDLYAMTGAAARAITSGRLSYAFDLRGPS
                     FTVDTACSSALVAVHNAVQAIRLGECPLAIAGGVNLVLLPEEGVVYSGAGMLASDGRCK
                     FADASGDGFVRSDGIGAVILKPLSAALADGDRIRAVIRGSAVGNDGQSSGYLVTPAVEG
                     QRDVLRRAYANAAVDPADIDYIEAHGTGTSVGDPVELQALADIVGARASDDRCLVGSVK
                     TNIGHAEAAAGIAGLIKAVLCLENKTIPPNLHLKNPNPTVDWANLPLAVPTHATPLPQR
                     DRPAIAGVSSFGFSGTNAHLVLEAAP"
     PFAM_domain     complement(26981..27331)
                     /aSDomain="Ketoacyl-synt_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02801.25"
                     /description="Beta-ketoacyl synthase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6827_0908"
                     /evalue="4.00E-42"
                     /label="SCO6827"
                     /locus_tag="SCO6827"
                     /protein_end="388"
                     /protein_start="271"
                     /score="143.1"
                     /tool="antismash"
                     /translation="AVIRGSAVGNDGQSSGYLVTPAVEGQRDVLRRAYANAAVDPADID
                     YIEAHGTGTSVGDPVELQALADIVGARASDDRCLVGSVKTNIGHAEAAAGIAGLIKAVL
                     CLENKTIPPNLHL"
     CDS_motif       complement(27047..27091)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0003"
                     /evalue="8.10E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="SCO6827"
                     /protein_end="366"
                     /protein_start="351"
                     /score="11.9"
                     /tool="antismash"
                     /translation="GSVKTNIGHAEAAAG"
     CDS_motif       complement(27149..27196)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0002"
                     /evalue="1.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="SCO6827"
                     /protein_end="332"
                     /protein_start="316"
                     /score="13.5"
                     /tool="antismash"
                     /translation="YIEAHGTGTSVGDPVE"
     PFAM_domain     complement(27356..28105)
                     /aSDomain="ketoacyl-synt"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00109.29"
                     /description="Beta-ketoacyl synthase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6827_0907"
                     /evalue="7.90E-88"
                     /label="SCO6827"
                     /locus_tag="SCO6827"
                     /protein_end="263"
                     /protein_start="13"
                     /score="294.4"
                     /tool="antismash"
                     /translation="EPIAIIGMAGRFADATSLEQLWDMLLQGRDAITDIPPDRYDVDAV
                     YDPTPRTPGRTVSRWGGLLHDIDAFDAEFFGISPREADRMDPQQRLLLEVAYEALEDAG
                     QPLPRIAGTDTGVFIGQLGGDYWHLQYDDRDQLDLYAMTGAAARAITSGRLSYAFDLRG
                     PSFTVDTACSSALVAVHNAVQAIRLGECPLAIAGGVNLVLLPEEGVVYSGAGMLASDGR
                     CKFADASGDGFVRSDGIGAVILKPLSAA"
     misc_feature    complement(27569..27619)
                     /gene_synonym="SC4A9.04c"
                     /locus_tag="SCO6827"
                     /note="PS00606 Beta-ketoacyl synthases active site"
     CDS_motif       complement(27572..27619)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6827_0001"
                     /evalue="1.70E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="SCO6827"
                     /protein_end="191"
                     /protein_start="175"
                     /score="19.9"
                     /tool="antismash"
                     /translation="GPSFTVDTACSSALVA"
     gene            28838..30319
                     /db_xref="GeneID:1102267"
                     /gene_synonym="SC4A9.05"
                     /locus_tag="SCO6828"
     CDS             28838..30319
                     /codon_start=1
                     /db_xref="GeneID:1102267"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092:hypothetical
                     protein (Score: 57.2; E-value: 2.8e-17)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC4A9.05"
                     /locus_tag="SCO6828"
                     /note="SC4A9.05, possible hypothetical protein, len: 493
                     aa. Highly similar to Streptomyces coelicolor hypothetical
                     protein SC1A2.20c (464 aa), fasta scores opt: 1389 z-score:
                     1246.8 E():0 51.0% identity in 455 aa overlap. Also weakly
                     similar to Streptomyces coelicolor
                     TR:CAB52349(EMBL:AL109747) flavin-containing monooxygenase
                     (458 aa), fasta scores opt: 151 z-score: 166.3 E(): 0.075
                     24.2% identity in 414 aa overlap. Contains a possible
                     N-terminal signal sequence."
                     /product="hypothetical protein"
                     /protein_id="NP_630899.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.8e-10, bitscore:
                     37.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDLGSDRLPVAVIGAGPVGLAAAAHLAERSVPFVVLEAGDAAAT
                     AVQAWSHIQLFSPWEFNTDPAARRLLAAAGWEEPDASALPTGGDLVKQYLQPLAELPAL
                     ASHIRYGAEVTAISRLGIDRLRTADRDAAPFVLRLADGEEVLARAVIDASGTWRQPNHV
                     GANGLPAHGEKDAAAWINHGLPDVFGADRDQHAGRHTVVVGAGHSAANTLLALAELADT
                     APGTTITWAIRGADPAASFGGGSDDELPARGAIGSGLKMLVETGRVTLAANFRTHAVRR
                     LGDDPSRDQVELVSRALDGTERSVTADRVVAATGFRPDYRIVDELRLELDPIMSAPRAL
                     APLIDPNQHSCGTVTPHGYRELAHPEPGYYAVGMKSYGRAPTFLMLTGYEQVRSIAAAL
                     AGDLEAAQSVELQLPETGVCSVTAGGEALALRLGLTKDQHEQLLHVTAKHLGTSATASD
                     AVLSAATELGIDQTAALQLAAYAADMFDAPGAPGC"
     PFAM_domain     28874..29818
                     /aSDomain="Pyr_redox_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13738.9"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6828_0917"
                     /evalue="1.10E-14"
                     /label="SCO6828"
                     /locus_tag="SCO6828"
                     /protein_end="327"
                     /protein_start="12"
                     /score="54.5"
                     /tool="antismash"
                     /translation="VIGAGPVGLAAAAHLAERSVPFVVLEAGDAAATAVQAWSHIQLFS
                     PWEFNTDPAARRLLAAAGWEEPDASALPTGGDLVKQYLQPLAELPALASHIRYGAEVTA
                     ISRLGIDRLRTADRDAAPFVLRLADGEEVLARAVIDASGTWRQPNHVGANGLPAHGEKD
                     AAAWINHGLPDVFGADRDQHAGRHTVVVGAGHSAANTLLALAELADTAPGTTITWAIRG
                     ADPAASFGGGSDDELPARGAIGSGLKMLVETGRVTLAANFRTHAVRRLGDDPSRDQVEL
                     VSRALDGTERSVTADRVVAATGFRPDYRIVDELR"
     gene            complement(30379..31158)
                     /db_xref="GeneID:1102268"
                     /gene_synonym="SC4A9.06c"
                     /locus_tag="SCO6829"
     CDS             complement(30379..31158)
                     /NRPS_PKS="Domain: PKS_KR (12-174). E-value: 1e-11. Score:
                     36.9. Matches aSDomain: nrpspksdomains_SCO6829_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:1102268"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     207.2; E-value: 4.7e-63)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC4A9.06c"
                     /locus_tag="SCO6829"
                     /note="SC4A9.06c, possible oxidoreductase, len: 259 aa.
                     Highly similar to Streptomyces coelicolor
                     TR:Q9X890(EMBL:AL049707) oxidoreductase, SCE15.15 (260 aa),
                     fasta scores opt: 1088 z-score: 1221.9 E(): 0 66.9%
                     identity in 254 aa overlap. Also similar to Streptomyces
                     griseus subsp. griseus TR:Q9XDF5(EMBL:AF074603) ketoacyl
                     reductase (271 aa), fasta scores opt: 421 z-score: 479.1
                     E(): 2.8e-19 36.7% identity in 256 aa overlap. Contains a
                     Prosite hit to PS00061 Short-chain
                     dehydrogenases/reductases family signature and a Pfam match
                     to entry PF00106 adh_short, short chain dehydrogenase."
                     /product="oxidoreductase"
                     /protein_id="NP_630900.1"
                     /sec_met_domain="adh_short (E-value: 1.9e-36, bitscore:
                     124.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTADTQAARTRTAVVTGASSGIGAATARALAREGFEVVLTARRA
                     DRLEAVAKEIRNDGGMVQVFPLDVTDREAVLAFAAQFPACDVLVNNAGGAYGTEHIENA
                     DPGDWRSMYEVNVIGALHMTQALLPALKASGDGVVVVISSTASFTCYEGGGGYSAAKHG
                     AHVLAETLRLEVCGEALRVVEIAPGMVHTEEFSLNRYRGDLNRADAVYAGVPDPLVADD
                     VADVVTWAVTRPPHVNIDLLVVRPRAQAAQHKVHRIT"
     PFAM_domain     complement(30580..31122)
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00106.28"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6829_0918"
                     /evalue="2.50E-49"
                     /label="SCO6829"
                     /locus_tag="SCO6829"
                     /protein_end="193"
                     /protein_start="12"
                     /score="167.5"
                     /tool="antismash"
                     /translation="TAVVTGASSGIGAATARALAREGFEVVLTARRADRLEAVAKEIRN
                     DGGMVQVFPLDVTDREAVLAFAAQFPACDVLVNNAGGAYGTEHIENADPGDWRSMYEVN
                     VIGALHMTQALLPALKASGDGVVVVISSTASFTCYEGGGGYSAAKHGAHVLAETLRLEV
                     CGEALRVVEIAPGMVHTE"
     misc_feature    complement(30580..31125)
                     /gene_synonym="SC4A9.06c"
                     /locus_tag="SCO6829"
                     /note="Pfam match to entry PF00106 adh_short, short chain
                     dehydrogenase, score 202.80, E-value 5.1e-57"
     aSDomain        complement(30637..31122)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO6829_PKS_KR.1"
                     /evalue="1.00E-11"
                     /label="SCO6829_PKS_KR.1"
                     /locus_tag="SCO6829"
                     /protein_end="174"
                     /protein_start="12"
                     /score="36.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TAVVTGASSGIGAATARALAREGFEVVLTARRADRLEAVAKEIRN
                     DGGMVQVFPLDVTDREAVLAFAAQFPACDVLVNNAGGAYGTEHIENADPGDWRSMYEVN
                     VIGALHMTQALLPALKASGDGVVVVISSTASFTCYEGGGGYSAAKHGAHVLAETLRLE"
     misc_feature    complement(30643..30729)
                     /gene_synonym="SC4A9.06c"
                     /locus_tag="SCO6829"
                     /note="PS00061 Short-chain dehydrogenases/reductases family
                     signature."
     CDS_motif       complement(31030..31116)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO6829_0001"
                     /evalue="6.00E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="SCO6829"
                     /protein_end="43"
                     /protein_start="14"
                     /score="15.7"
                     /tool="antismash"
                     /translation="VVTGASSGIGAATARALAREGFEVVLTAR"
     gene            31243..31596
                     /db_xref="GeneID:1102269"
                     /gene_synonym="SC4A9.07"
                     /locus_tag="SCO6830"
     CDS             31243..31596
                     /codon_start=1
                     /db_xref="GeneID:1102269"
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 83.1; E-value: 1.7e-25)"
                     /gene_kind="regulatory"
                     /gene_synonym="SC4A9.07"
                     /locus_tag="SCO6830"
                     /note="SC4A9.07, possible ArsR-family transcriptional
                     regulator, len: 117 aa. Highly similar to Streptomyces
                     coelicolor TR:Q9X8X8 (EMBL:AL078610) transcriptional
                     regulator SCH35.28C (122 aa), fasta scores opt: 561
                     z-score: 746.6 E():0 78.0% identity in 109 aa overlap and
                     Mycobacterium tuberculosis TR:P71941 (EMBL:Z80225)
                     transcriptional regulator (126 aa), fasta scores opt: 359
                     z-score: 482.6 E(): 1.8e-19 56.9% identity in 116 aa
                     overlap. Also similar to several other Streptomyces
                     coelicolor ArsR-family transcriptional regulators
                     including: SC1A2.21 (119 aa), fasta scores opt: 491
                     z-score: 582.6 E(): 5.2e-27 64.7% identity in 116 aa
                     overlap and SC1A2.17c (120 aa), fasta scores opt: 295
                     z-score: 356.1 E(): 2.1e-14 45.5% identity in 99 aa
                     overlap. Contains a Pfam match to entry PF01022 HTH_5,
                     Bacterial regulatory protein, arsR family."
                     /product="transcription regulator ArsR"
                     /protein_id="NP_630901.1"
                     /transl_table=11
                     /translation="MSKLAQLAATASAPPCCPSLTDRELTDEEAEVTAAMFKALGDPVR
                     LRLFSKVASHPEGEACVCDIADVGVSQPTVSHHLKKLREAGLLLSERRGTWVYYRLAPS
                     VLAALSGLLTTRD"
     misc_feature    31351..31590
                     /gene_synonym="SC4A9.07"
                     /locus_tag="SCO6830"
                     /note="Pfam match to entry PF01022 HTH_5, Bacterial
                     regulatory protein, arsR family, score 91.70, E-value
                     1.4e-23"
     PFAM_domain     31366..31506
                     /aSDomain="HTH_5"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01022.23"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory protein, arsR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6830_0919"
                     /evalue="1.40E-14"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO6830"
                     /locus_tag="SCO6830"
                     /protein_end="88"
                     /protein_start="41"
                     /score="53.8"
                     /tool="antismash"
                     /translation="DPVRLRLFSKVASHPEGEACVCDIADVGVSQPTVSHHLKKLREAG
                     LL"
     gene            32087..32362
                     /db_xref="GeneID:1102270"
                     /gene_synonym="SC4A9.08"
                     /locus_tag="SCO6831"
     CDS             32087..32362
                     /codon_start=1
                     /db_xref="GeneID:1102270"
                     /gene_synonym="SC4A9.08"
                     /locus_tag="SCO6831"
                     /note="SC4A9.08, unknown, len: 91 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_630902.1"
                     /transl_table=11
                     /translation="MTSTILTTAQAHSHNILRSDGDRAAEPNIFLAGGKDIPEDQRMHE
                     VEPLTDRVKLNVENRYEHFEATSEVREVDGRSLRVYGWIYRTYVAE"
     PFAM_domain     32159..32359
                     /aSDomain="DUF5988"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19450.2"
                     /description="Family of unknown function (DUF5988)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6831_0920"
                     /evalue="2.10E-23"
                     /label="SCO6831"
                     /locus_tag="SCO6831"
                     /protein_end="91"
                     /protein_start="24"
                     /score="82.2"
                     /tool="antismash"
                     /translation="AEPNIFLAGGKDIPEDQRMHEVEPLTDRVKLNVENRYEHFEATSE
                     VREVDGRSLRVYGWIYRTYVAE"
     gene            32418..34013
                     /db_xref="GeneID:1102271"
                     /gene_synonym="mutA"
                     /locus_tag="SCO6832"
     CDS             32418..34013
                     /codon_start=1
                     /db_xref="GeneID:1102271"
                     /gene_synonym="mutA"
                     /locus_tag="SCO6832"
                     /note="SC4A9.09, mutA, methylmalonyl-CoA mutase (EC
                     5.4.99.2), len: 531 aa. Highly similar to many members of
                     the methylmalonyll-CoA mutase family including:
                     Sinorhizobium meliloti TR:O86028(EMBL:AF080073)
                     methylmalonyll-CoA mutase (EC 5.4.99.2) (712 aa), fasta
                     scores opt: 1720 z-score: 1946.7 E(): 0 52.2% identity in
                     515 aa overlap and Pyrococcus abyssi
                     TR:CAB49756(EMBL:AJ248285) methylmalonyl-CoA mutase,
                     subunit alpha, N-terminus (562 aa), fasta scores opt: 2180
                     z-score: 2469.0 E():0 62.7% identity in 518 aa overlap.
                     Also highly similar to Streptomyces coelicolor
                     TR:Q9X949(EMBL:AJ237976) isobutyryl-CoA mutase A (EC
                     5.4.99.13), SC8F4.19 (566 aa), fasta scores opt: 1515
                     z-score: 1556.8 E():0 50.5% identity in 541 aa overlap.
                     Contains a Pfam match to entry PF01642 MM_CoA_mutase,
                     Methylmalonyl-CoA mutase."
                     /product="methylmalonyll-CoA mutase"
                     /protein_id="NP_630903.1"
                     /transl_table=11
                     /translation="MARESASARTSESGLPIEPVYGPDALADWDAAEKLGEPGKYPFTR
                     GVYPSMYTGRPWTMRQYAGFGTATESNARYKQLIANGTMGLSVAFDLPTQMGHDSDAPI
                     ASGEVGKVGVAIDSIDDMRVLFGGIPLDKVSTSMTINAPASLLLLLYQLVAEEQGVSAD
                     KLTGTIQNDVLKEYIARGTYIFPPKPSLRLIADIFKYCRAEIPKWNTISISGYHMAEAG
                     ASPAQEIAFTLADGIEYVRTAVAAGMDVDDFAPRLSFFFVARTTILEEVAKFRAARRIW
                     ARVMKEEFGAKNPKSLMLRFHTQTAGVQLTAQQPEVNLVRVAVQGLGAVLGGTQSLHTN
                     SFDEAIALPTDKSARLALRTQQVLAYETDVTATVDPFAGSYVVERMTDDVEAAALELMG
                     KVEDLGGAVNAIEHGFQKNEIERSAYRIAQETDSGERVVVGVNRFQLDEEEPYEPLRVD
                     PAIEAQQAERLAKLRAERDQQAVDSALAALRKAAEGEDNVLYPMKDALRARATVGEVCN
                     ALREVWGTYVPSDL"
     aSDomain        32448..33998
                     /aSDomain="TIGR00641"
                     /aSTool="tigrfam"
                     /description="acid_CoA_mut_N: methylmalonyl-CoA mutase
                     N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6832_0108"
                     /evalue="2.30E-238"
                     /identifier="TIGR00641"
                     /label="SCO6832"
                     /locus_tag="SCO6832"
                     /protein_end="527"
                     /protein_start="10"
                     /score="789.7"
                     /tool="antismash"
                     /translation="SESGLPIEPVYGPDALADWDAAEKLGEPGKYPFTRGVYPSMYTGR
                     PWTMRQYAGFGTATESNARYKQLIANGTMGLSVAFDLPTQMGHDSDAPIASGEVGKVGV
                     AIDSIDDMRVLFGGIPLDKVSTSMTINAPASLLLLLYQLVAEEQGVSADKLTGTIQNDV
                     LKEYIARGTYIFPPKPSLRLIADIFKYCRAEIPKWNTISISGYHMAEAGASPAQEIAFT
                     LADGIEYVRTAVAAGMDVDDFAPRLSFFFVARTTILEEVAKFRAARRIWARVMKEEFGA
                     KNPKSLMLRFHTQTAGVQLTAQQPEVNLVRVAVQGLGAVLGGTQSLHTNSFDEAIALPT
                     DKSARLALRTQQVLAYETDVTATVDPFAGSYVVERMTDDVEAAALELMGKVEDLGGAVN
                     AIEHGFQKNEIERSAYRIAQETDSGERVVVGVNRFQLDEEEPYEPLRVDPAIEAQQAER
                     LAKLRAERDQQAVDSALAALRKAAEGEDNVLYPMKDALRARATVGEVCNALREVWGTYV
                     "
     PFAM_domain     32451..33989
                     /aSDomain="MM_CoA_mutase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01642.25"
                     /db_xref="GO:0016866"
                     /db_xref="GO:0031419"
                     /description="Methylmalonyl-CoA mutase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6832_0921"
                     /evalue="4.60E-224"
                     /gene_ontologies="GO:0016866: intramolecular transferase
                     activity"
                     /gene_ontologies="GO:0031419: cobalamin binding"
                     /label="SCO6832"
                     /locus_tag="SCO6832"
                     /protein_end="524"
                     /protein_start="11"
                     /score="744.9"
                     /tool="antismash"
                     /translation="ESGLPIEPVYGPDALADWDAAEKLGEPGKYPFTRGVYPSMYTGRP
                     WTMRQYAGFGTATESNARYKQLIANGTMGLSVAFDLPTQMGHDSDAPIASGEVGKVGVA
                     IDSIDDMRVLFGGIPLDKVSTSMTINAPASLLLLLYQLVAEEQGVSADKLTGTIQNDVL
                     KEYIARGTYIFPPKPSLRLIADIFKYCRAEIPKWNTISISGYHMAEAGASPAQEIAFTL
                     ADGIEYVRTAVAAGMDVDDFAPRLSFFFVARTTILEEVAKFRAARRIWARVMKEEFGAK
                     NPKSLMLRFHTQTAGVQLTAQQPEVNLVRVAVQGLGAVLGGTQSLHTNSFDEAIALPTD
                     KSARLALRTQQVLAYETDVTATVDPFAGSYVVERMTDDVEAAALELMGKVEDLGGAVNA
                     IEHGFQKNEIERSAYRIAQETDSGERVVVGVNRFQLDEEEPYEPLRVDPAIEAQQAERL
                     AKLRAERDQQAVDSALAALRKAAEGEDNVLYPMKDALRARATVGEVCNALREVWG"
     misc_feature    32559..34010
                     /gene_synonym="mutA"
                     /locus_tag="SCO6832"
                     /note="Pfam match to entry PF01642 MM_CoA_mutase,
                     Methylmalonyl-CoA mutase, score 864.90, E-value 2.6e-256"
     regulatory      34044..34048
                     /regulatory_class="ribosome_binding_site"
     gene            34057..34536
                     /db_xref="GeneID:1102272"
                     /gene_synonym="SC3D9.01"
                     /locus_tag="SCO6833"
     CDS             34057..34536
                     /codon_start=1
                     /db_xref="GeneID:1102272"
                     /gene_synonym="SC3D9.01"
                     /locus_tag="SCO6833"
                     /note="SC3D9.01, probable isobutyryl-CoA mutase, small
                     subunit (EC 5.4.99.13), len: 159 aa. Highly similar to
                     Streptomyces cinnamonensis TR:CAB59633 (EMBL:AJ246005)
                     isobutyryl-CoA mutase, small subunit (EC 5.4.99.13) (136
                     aa), fasta scores opt: 580 z-score: 685.3 E(): 9.2e-31
                     68.3% identity in 126 aa overlap and to the C-terminus of
                     Streptomyces cinnamonensis SW:MUTB_STRCM (EMBL:L10064)
                     methylmalonyl-CoA mutase alpha-subunit (EC 5.4.99.2) (733
                     aa), fasta scores opt: 291 z-score: 341.2 E(): 1.4e-11
                     40.5% identity in 111 aa overlap."
                     /product="isobutyryl-CoA mutase, small subunit"
                     /protein_id="NP_630904.1"
                     /transl_table=11
                     /translation="MRQLPMRVVVAKPGLDGHDRGAKVVARALRDAGVEVIYTGLHQTP
                     AQIVATAIQEDADGIGLSVLSGAHMTAFTEVMKLIQLEEATNIIVFGGGIIPDDDAANL
                     LEGGVAALFTPGTSMATVVDWVTNHVGGRRTGRVLAQPVPHSAQAAPAGPFQRSR"
     PFAM_domain     34072..34413
                     /aSDomain="B12-binding"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02310.22"
                     /db_xref="GO:0031419"
                     /db_xref="GO:0046872"
                     /description="B12 binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6833_0922"
                     /evalue="1.00E-24"
                     /gene_ontologies="GO:0031419: cobalamin binding"
                     /gene_ontologies="GO:0046872: metal ion binding"
                     /label="SCO6833"
                     /locus_tag="SCO6833"
                     /protein_end="119"
                     /protein_start="5"
                     /score="87.0"
                     /tool="antismash"
                     /translation="MRVVVAKPGLDGHDRGAKVVARALRDAGVEVIYTGLHQTPAQIVA
                     TAIQEDADGIGLSVLSGAHMTAFTEVMKLIQLEEATNIIVFGGGIIPDDDAANLLEGGV
                     AALFTPGTSM"
     aSDomain        34072..34449
                     /aSDomain="TIGR00640"
                     /aSTool="tigrfam"
                     /description="acid_CoA_mut_C: methylmalonyl-CoA mutase
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6833_0109"
                     /evalue="7.20E-44"
                     /identifier="TIGR00640"
                     /label="SCO6833"
                     /locus_tag="SCO6833"
                     /protein_end="131"
                     /protein_start="5"
                     /score="146.9"
                     /tool="antismash"
                     /translation="MRVVVAKPGLDGHDRGAKVVARALRDAGVEVIYTGLHQTPAQIVA
                     TAIQEDADGIGLSVLSGAHMTAFTEVMKLIQLEEATNIIVFGGGIIPDDDAANLLEGGV
                     AALFTPGTSMATVVDWVTNHVG"
     misc_feature    complement(34814..36613)
                     /note="previously sequenced and shares 100 % identity with
                     S.coelicolor (EMBL:AJ251005) arsC gene, trxB gene and arsR
                     gene locus."
     gene            complement(34850..35830)
                     /db_xref="GeneID:1102273"
                     /gene_synonym="trxB2"
                     /locus_tag="SCO6834"
     CDS             complement(34850..35830)
                     /codon_start=1
                     /db_xref="GeneID:1102273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176:alkyl hydroperoxide reductase subunit (Score:
                     371.6; E-value: 1e-112)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="trxB2"
                     /locus_tag="SCO6834"
                     /note="SC3D9.02c, trxB2, possible thioredoxin reductase
                     (326 aa). Previously sequenced and consequently identical
                     to Streptomyces coelicolor TR:CAB61258 (EMBL:AJ251005).
                     Also highly similar to the other Streptomyces coelicolor
                     trxB CDS: SW:TRXB_STRCO(EMBL:X92105) thioredoxin reductase
                     (EC 1.6.4.5) SCH24.12 (321 aa), fasta scores opt: 1547
                     z-score: 1709.6 E():0 74.2% identity in 310 aa overlap.
                     Contains a Prosite hit to PS00573 Pyridine
                     nucleotide-disulphide oxidoreductases class-II active
                     site."
                     /product="thioredoxin reductase"
                     /protein_id="NP_630905.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-41, bitscore:
                     141.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAKDVRDVIVIGSGPAGYTAALYTARASLNPLVFGGAIFVGGS
                     LTTTTEVENFPGFPDGVQGPELMENMRAQAERFGAEMVDDDIVAVDLTGDVKTVTDTAG
                     TVHRARTVIVATGSGYRKLGVPKEDELSGRGVSWCATCDGFFFRDRDIVVVGGGDTAME
                     EATFLTRFARSVTVVHRRSALRASQVMQNRAFSEDKISLAFDSEVATLHEENGMLSGMT
                     LRDTLTGETRELATTGLFIAIGHDPRTELFKGQLHLDSEGYLMVESPSTRTNVPGVFGA
                     GDVVDHTYRQAITAASSGCAAALDAERYLAARSDTSVSAEVVAVA"
     aSDomain        complement(34901..35806)
                     /aSDomain="TIGR01292"
                     /aSTool="tigrfam"
                     /description="TRX_reduct: thioredoxin-disulfide reductase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6834_0110"
                     /evalue="3.50E-114"
                     /identifier="TIGR01292"
                     /label="SCO6834"
                     /locus_tag="SCO6834"
                     /protein_end="310"
                     /protein_start="8"
                     /score="378.6"
                     /tool="antismash"
                     /translation="DVIVIGSGPAGYTAALYTARASLNPLVFGGAIFVGGSLTTTTEVE
                     NFPGFPDGVQGPELMENMRAQAERFGAEMVDDDIVAVDLTGDVKTVTDTAGTVHRARTV
                     IVATGSGYRKLGVPKEDELSGRGVSWCATCDGFFFRDRDIVVVGGGDTAMEEATFLTRF
                     ARSVTVVHRRSALRASQVMQNRAFSEDKISLAFDSEVATLHEENGMLSGMTLRDTLTGE
                     TRELATTGLFIAIGHDPRTELFKGQLHLDSEGYLMVESPSTRTNVPGVFGAGDVVDHTY
                     RQAITAASSGCAAALDAERYL"
     PFAM_domain     complement(34934..35806)
                     /aSDomain="Pyr_redox_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07992.17"
                     /db_xref="GO:0016491"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6834_0923"
                     /evalue="2.80E-41"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO6834"
                     /locus_tag="SCO6834"
                     /protein_end="299"
                     /protein_start="8"
                     /score="141.8"
                     /tool="antismash"
                     /translation="DVIVIGSGPAGYTAALYTARASLNPLVFGGAIFVGGSLTTTTEVE
                     NFPGFPDGVQGPELMENMRAQAERFGAEMVDDDIVAVDLTGDVKTVTDTAGTVHRARTV
                     IVATGSGYRKLGVPKEDELSGRGVSWCATCDGFFFRDRDIVVVGGGDTAMEEATFLTRF
                     ARSVTVVHRRSALRASQVMQNRAFSEDKISLAFDSEVATLHEENGMLSGMTLRDTLTGE
                     TRELATTGLFIAIGHDPRTELFKGQLHLDSEGYLMVESPSTRTNVPGVFGAGDVVDHTY
                     RQAITAASSG"
     misc_feature    complement(35354..35416)
                     /gene_synonym="trxB2"
                     /locus_tag="SCO6834"
                     /note="PS00573 Pyridine nucleotide-disulphide
                     oxidoreductases class-II active site"
     gene            complement(35827..36240)
                     /db_xref="GeneID:1102274"
                     /gene_synonym="arsC"
                     /locus_tag="SCO6835"
     CDS             complement(35827..36240)
                     /codon_start=1
                     /db_xref="GeneID:1102274"
                     /gene_synonym="arsC"
                     /locus_tag="SCO6835"
                     /note="SC3D9.03c, arsC, possible arsenate reductase, len:
                     137 aa. Previously sequenced and consequently identical to
                     Streptomyces coelicolor TR:CAB61257(EMBL:AJ251005). Also
                     highly similar to Streptomyces coelicolor
                     TR:Q9X8Y2(EMBL:AL078610) heavy metal reductase, SCH35.24C
                     (137 aa), fasta scores opt: 863 z-score: 986.3 E(): 0 92.7%
                     identity in 137 aa overlap. Contains a Pfam match to entry
                     PF01451 LMWPc, Low molecular weight phosphotyrosine protein
                     phosphatase."
                     /product="arsenate reductase"
                     /protein_id="NP_630906.1"
                     /transl_table=11
                     /translation="MSDKPSVLFVCVHNAGRSQMAAAWLTHLAGGRVEVRSAGSTPGEN
                     VNPAAVEAMAEVGIDISAEVPKLLTADAVKESDVCITMGCGDTCPVFPGKRYLDWQLDD
                     PAGQGVEAVRPIRDEIRVLVEGLIKEIAPEPQS"
     misc_feature    complement(35851..36228)
                     /gene_synonym="arsC"
                     /locus_tag="SCO6835"
                     /note="Pfam match to entry PF01451 LMWPc, Low molecular
                     weight phosphotyrosine protein phosphatase, score 144.50,
                     E-value 1.8e-39"
     PFAM_domain     complement(35860..36222)
                     /aSDomain="LMWPc"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01451.24"
                     /description="Low molecular weight phosphotyrosine protein
                     phosphatase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6835_0924"
                     /evalue="1.50E-21"
                     /label="SCO6835"
                     /locus_tag="SCO6835"
                     /protein_end="127"
                     /protein_start="6"
                     /score="77.4"
                     /tool="antismash"
                     /translation="VLFVCVHNAGRSQMAAAWLTHLAGGRVEVRSAGSTPGENVNPAAV
                     EAMAEVGIDISAEVPKLLTADAVKESDVCITMGCGDTCPVFPGKRYLDWQLDDPAGQGV
                     EAVRPIRDEIRVLVEGL"
     gene            36333..36641
                     /db_xref="GeneID:1102275"
                     /gene_synonym="arsR; SC3D9.04"
                     /locus_tag="SCO6836"
     CDS             36333..36641
                     /codon_start=1
                     /db_xref="GeneID:1102275"
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 78.7; E-value: 4e-24)"
                     /gene_kind="regulatory"
                     /gene_synonym="arsR; SC3D9.04"
                     /locus_tag="SCO6836"
                     /note="SC3D9.04, arsR, possible ArsR-family transcriptional
                     regulator, len: 102 aa. Previously partially sequenced and
                     consequently identical to Streptomyces coelicolor
                     TR:CAB61256 (EMBL:AJ251005) transcriptional regulator
                     (fragment) (>93 aa). Also highly similar to Streptomyces
                     coelicolor TR:Q9X8Y1(EMBL:AL078610) transcriptional
                     regulator, SCH35.25 (102 aa), fasta scores opt: 617
                     z-score: 838.5 E(): 0 95.1% identity in 102 aa overlap.
                     Contains a Pfam match to entry PF01022 HTH_5, Bacterial
                     regulatory protein, arsR family."
                     /product="transcription regulator ArsR"
                     /protein_id="NP_630907.1"
                     /transl_table=11
                     /translation="MMTSVDTDLIRVLADPLRLQIVTLLANETLCTTHLVEETGARQTN
                     LSNHLRVLREAGVVETEPCGRYTYYKLRPDVIASLAGQFADLAESARNAADNKRACP"
     misc_feature    36360..36593
                     /gene_synonym="arsR; SC3D9.04"
                     /locus_tag="SCO6836"
                     /note="Pfam match to entry PF01022 HTH_5, Bacterial
                     regulatory protein, arsR family, score 52.00, E-value
                     1.3e-11"
     PFAM_domain     36375..36512
                     /aSDomain="HTH_5"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01022.23"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory protein, arsR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6836_0925"
                     /evalue="3.80E-13"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO6836"
                     /locus_tag="SCO6836"
                     /protein_end="60"
                     /protein_start="14"
                     /score="49.2"
                     /tool="antismash"
                     /translation="DPLRLQIVTLLANETLCTTHLVEETGARQTNLSNHLRVLREAGVV
                     E"
     gene            36638..37744
                     /db_xref="GeneID:1102276"
                     /gene_synonym="SC3D9.05"
                     /locus_tag="SCO6837"
     CDS             36638..37744
                     /codon_start=1
                     /db_xref="GeneID:1102276"
                     /gene_synonym="SC3D9.05"
                     /locus_tag="SCO6837"
                     /note="SC3D9.05, possible arsenic resistance membrane
                     transport protein, len: 368 aa. Highly similar to
                     Streptomyces coelicolor TR:Q9X8Y0(EMBL:AL078610) heavy
                     metal resistance membrane protein, SCH35.26 (369 aa), fasta
                     scores opt: 2304 z-score: 2675.9 E(): 0 95.4% identity in
                     369 aa overlap and Sinorhizobium sp. As4.
                     TR:AAD51846(EMBL:AF178758) membrane subunit of arsenic
                     oxyanion-translocation pump, ArsB (351 aa), fasta scores
                     opt: 1263 z-score: 1469.8 E():0 53.8% identity in 344 aa
                     overlap. Contains possible membrane spanning hydrophobic
                     domains and a Pfam match to entry PF01758 SBF, Sodium Bile
                     acid symporter family."
                     /product="arsenic resistance membrane transport protein"
                     /protein_id="NP_630908.1"
                     /transl_table=11
                     /translation="MTRTEAPAITEEPSVVAKLSTLDRFLAVWILIAMAVGLGLGRAIP
                     GLNDALAEVEIGGISLPIAIGLLIMMYPVLAKVRYDKLDAVTGDRRLMASSLVINWIVG
                     PAVMFALAWIFLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAAAVLVALNSVFQ
                     VLAFGLLGWFYLDLLPGWLGLGDGEHLDISMWKIALNVVIFLGVPLLAGFLTRRIGEKK
                     LGREKYESNFLPKIGPWALYGLLFTIVILFALQGKTITSQPLDVARIALPLLVYFAVMW
                     AGTFLLGKTIGLAYDRTATLAFTAAGNNFELAIAVAIATFGVTSGQALSGVVGPLIEVP
                     VLIGLVYVSLAWRKKFTPSAPVTEGRGY"
     aSDomain        36692..37681
                     /aSDomain="TIGR00832"
                     /aSTool="tigrfam"
                     /description="acr3: arsenical-resistance protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6837_0111"
                     /evalue="5.40E-132"
                     /identifier="TIGR00832"
                     /label="SCO6837"
                     /locus_tag="SCO6837"
                     /protein_end="348"
                     /protein_start="18"
                     /score="438.0"
                     /tool="antismash"
                     /translation="LSTLDRFLAVWILIAMAVGLGLGRAIPGLNDALAEVEIGGISLPI
                     AIGLLIMMYPVLAKVRYDKLDAVTGDRRLMASSLVINWIVGPAVMFALAWIFLPDLPEY
                     RTGLIIVGLARCIAMVIIWNDLACGDREAAAVLVALNSVFQVLAFGLLGWFYLDLLPGW
                     LGLGDGEHLDISMWKIALNVVIFLGVPLLAGFLTRRIGEKKLGREKYESNFLPKIGPWA
                     LYGLLFTIVILFALQGKTITSQPLDVARIALPLLVYFAVMWAGTFLLGKTIGLAYDRTA
                     TLAFTAAGNNFELAIAVAIATFGVTSGQALSGVVGPLIEVPVLIGLVYV"
     PFAM_domain     36827..37420
                     /aSDomain="SBF"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01758.19"
                     /db_xref="GO:0016020"
                     /description="Sodium Bile acid symporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6837_0926"
                     /evalue="1.00E-61"
                     /gene_ontologies="GO:0016020: membrane"
                     /label="SCO6837"
                     /locus_tag="SCO6837"
                     /protein_end="261"
                     /protein_start="63"
                     /score="208.2"
                     /tool="antismash"
                     /translation="AIGLLIMMYPVLAKVRYDKLDAVTGDRRLMASSLVINWIVGPAVM
                     FALAWIFLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAAAVLVALNSVFQVLAF
                     GLLGWFYLDLLPGWLGLGDGEHLDISMWKIALNVVIFLGVPLLAGFLTRRIGEKKLGRE
                     KYESNFLPKIGPWALYGLLFTIVILFALQGKTITS"
     misc_feature    36827..37423
                     /gene_synonym="SC3D9.05"
                     /locus_tag="SCO6837"
                     /note="Pfam match to entry PF01758 SBF, Sodium Bile acid
                     symporter family, score 252.90, E-value 4.3e-72"
     gene            37803..38867
                     /db_xref="GeneID:1102277"
                     /gene_synonym="SC3D9.06"
                     /locus_tag="SCO6838"
     CDS             37803..38867
                     /codon_start=1
                     /db_xref="GeneID:1102277"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="other (smcogs) SMCOG1092:hypothetical
                     protein (Score: 227.5; E-value: 6e-69)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC3D9.06"
                     /locus_tag="SCO6838"
                     /note="SC3D9.06, possible monooxygenase, len: 354 aa.
                     Highly similar to Streptomyces coelicolor
                     TR:Q9X8X9(EMBL:AL078610) oxidoreductase, SCH35.27 (406 aa),
                     fasta scores opt: 1377 z-score: 1503.9 E():0 66.7% identity
                     in 327 aa overlap. Also similar to Streptomyces coelicolor
                     TR:CAB59668(EMBL:AL132674) monooxygenase, SCE87.23C (519
                     aa), fasta scores opt: 355 z-score: 390.5 E(): 2.4e-14
                     28.6% identity in 371 aa overlap. Contains a Pfam match to
                     entry PF00743 FMO-like, Flavin-binding monooxygenase-like."
                     /product="monooxygenase"
                     /protein_id="NP_630909.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-14, bitscore:
                     52.8, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 2.1e-07, bitscore: 29.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQHTDVVVIGGGQAGLAAGYHLRRQGLDFVVLDAQAAPGGAWQH
                     TWDSLHLFSPAAFSSLPGRLMPPQPGKEYPDAGHVVAYLNDYEKRYDLPVQRAVRVIGV
                     HDDGRLLRVETDSGTWRARAVISATGMWWRPFLPAVPGREDFEGRQLHTVSYRRPQDFA
                     GQRVIVVGGGNSGAQIAADLAHDTELTWVTQRPPRYLADDIDGRALFDAATARRRALDD
                     GRTDTGGVASLGDIVAVPPVREARDAGRLKASPMFARLVRDGVVWDDGTRAPADAVIWC
                     TGFRPALSHLSPLGLRGSRGHIDTVGTRAAADPRLHLLGYGDWTGPASATLIGVGRPAR
                     DAAREIAEFLGGEG"
     misc_feature    37821..38852
                     /gene_synonym="SC3D9.06"
                     /locus_tag="SCO6838"
                     /note="Pfam match to entry PF00743 FMO-like, Flavin-binding
                     monooxygenase-like, score -301.00, E-value 2.4e-06"
     PFAM_domain     37824..38387
                     /aSDomain="Pyr_redox_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13738.9"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6838_0927"
                     /evalue="6.10E-29"
                     /label="SCO6838"
                     /locus_tag="SCO6838"
                     /protein_end="195"
                     /protein_start="7"
                     /score="101.4"
                     /tool="antismash"
                     /translation="VVIGGGQAGLAAGYHLRRQGLDFVVLDAQAAPGGAWQHTWDSLHL
                     FSPAAFSSLPGRLMPPQPGKEYPDAGHVVAYLNDYEKRYDLPVQRAVRVIGVHDDGRLL
                     RVETDSGTWRARAVISATGMWWRPFLPAVPGREDFEGRQLHTVSYRRPQDFAGQRVIVV
                     GGGNSGAQIAADLAHDTELTWVTQR"
     gene            complement(39041..40354)
                     /db_xref="GeneID:1102278"
                     /gene_synonym="SC3D9.07c"
                     /locus_tag="SCO6839"
     CDS             complement(39041..40354)
                     /codon_start=1
                     /db_xref="GeneID:1102278"
                     /gene_synonym="SC3D9.07c"
                     /locus_tag="SCO6839"
                     /note="SC3D9.07c, unknown, len: 437 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_630910.1"
                     /transl_table=11
                     /translation="MTSLEEPGATDPTGQLLTAQTSYLEELIRRANSPGNLDGLLAHYV
                     LGGRRLSFDWEVNPMTPTWLADNKDRFAHPHGLAGLGYGLASFPSTASRTAREHLAAGL
                     PALTRRNPFPPDGVAFVNDARQVIGLALAVDAARDDVPRAHDWLVEVLQDPRLRAANTL
                     LGLFHEHARQIVGIAPDLRVDPRAVHDLVDAACFHWLTATAKSPLRTDHDELRQLRSRL
                     LSGIILTDTGQLPAPRAALLLDAVTRIVTASVDDMLLSRDHVSVLLRRFETAMRQWRHD
                     RDDLENPIKWPITSEREIQNILWLMLRPVFDDLVDEETLRRIGHSTYRADFGIPSLELL
                     IEVKYARKAADFKSFEKEIFEDYIGYLSDNTAYRHMTVFIYDESCSGQEHDTTRNALLR
                     LSGITDVIIVSRPSHIPIPGRTPRRRRGSGQRDDASSN"
     PFAM_domain     complement(39116..39568)
                     /aSDomain="DpnII-MboI"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF18742.4"
                     /description="REase_DpnII-MboI"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6839_0928"
                     /evalue="1.10E-36"
                     /label="SCO6839"
                     /locus_tag="SCO6839"
                     /protein_end="413"
                     /protein_start="262"
                     /score="125.7"
                     /tool="antismash"
                     /translation="HVSVLLRRFETAMRQWRHDRDDLENPIKWPITSEREIQNILWLML
                     RPVFDDLVDEETLRRIGHSTYRADFGIPSLELLIEVKYARKAADFKSFEKEIFEDYIGY
                     LSDNTAYRHMTVFIYDESCSGQEHDTTRNALLRLSGITDVIIVSRPS"
     gene            complement(40351..42396)
                     /db_xref="GeneID:1102279"
                     /gene_synonym="SC3D9.08c"
                     /locus_tag="SCO6840"
     CDS             complement(40351..42396)
                     /codon_start=1
                     /db_xref="GeneID:1102279"
                     /gene_synonym="SC3D9.08c"
                     /locus_tag="SCO6840"
                     /note="SC3D9.08c, unknown, len: 681 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_630911.1"
                     /transl_table=11
                     /translation="MRLVQEALLRSVLGWGYKLRRRVPPVFVSRLPGKDLLEPSVRGRR
                     QGALGKLHVYPEFRLDSRAIGPSNHPGVIVGVKSRYEIDMTVEELIHHGVDVRGLYVLS
                     EDVTVEADPTMDRHAARRAVGAIDHIDGTDLVLRDAPGITRVAAGHAWLESRRETFNDV
                     LSTLAGADSGQILRELEQATFDLLGAFGRYEGAVRIGTRLGRNGALPVADDLSVTIDPP
                     VGSSNGRKVTGTRYESPTFQFDQAGDKTSRSADRGLDEFGPFDVEFFARKRPRIAVVTP
                     RAHKGVVENFLTKFLYGIQGARVFGLGFIRKYHLSGCDIAMHAFDGTATDAGAYREACR
                     AALSSGDIDLAIVITSEAQAHLTGDSSPYLVAKSAFMGQGVPVQEVRIETVRQSKLAYP
                     LNSIALACYAKLGGIPFVIAAPRTLAHELVIGIGSAHVKESRLTEPERVVGITTVFSAD
                     GNYLLWNTSREADYDDYPRELLLSLRDCIDTIKNRNAWQAGDELRLVFHVFKPLKDVEA
                     TAVKKLVEGLTQTYAKVEFAFVHVSTDHDWVMFDRTSAGIRGWGADSRTKGHYVPERGH
                     AVPMGKRELLVAVGGPMDLKSALHGVPKPLLLKLHPQSTFTDIEYLGRQAFRFTSMSWR
                     NMYPSRNPVTISYSDLIAELLGHLRHVRNWNADAVTTKLRSSRWFL"
     PFAM_domain     complement(40426..41271)
                     /aSDomain="Piwi"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02171.20"
                     /db_xref="GO:0003676"
                     /description="Piwi domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6840_0929"
                     /evalue="3.50E-08"
                     /gene_ontologies="GO:0003676: nucleic acid binding"
                     /label="SCO6840"
                     /locus_tag="SCO6840"
                     /protein_end="657"
                     /protein_start="375"
                     /score="33.2"
                     /tool="antismash"
                     /translation="FMGQGVPVQEVRIETVRQSKLAYPLNSIALACYAKLGGIPFVIAA
                     PRTLAHELVIGIGSAHVKESRLTEPERVVGITTVFSADGNYLLWNTSREADYDDYPREL
                     LLSLRDCIDTIKNRNAWQAGDELRLVFHVFKPLKDVEATAVKKLVEGLTQTYAKVEFAF
                     VHVSTDHDWVMFDRTSAGIRGWGADSRTKGHYVPERGHAVPMGKRELLVAVGGPMDLKS
                     ALHGVPKPLLLKLHPQSTFTDIEYLGRQAFRFTSMSWRNMYPSRNPVTISYSDLIAELL
                     G"
     gene            42924..43976
                     /db_xref="GeneID:1102280"
                     /gene_synonym="SC3D9.09"
                     /locus_tag="SCO6841"
     CDS             42924..43976
                     /codon_start=1
                     /db_xref="GeneID:1102280"
                     /gene_synonym="SC3D9.09"
                     /locus_tag="SCO6841"
                     /note="SC3D9.09, unknown, len: 350 aa. Similar to
                     Streptomyces coelicolor TR:Q9X865 (EMBL:AL049661)
                     hypothetical protein SCE134.10 (320 aa), fasta scores opt:
                     589 z-score: 714.3 E(): 2.2e-32 46.0% identity in 313 aa
                     overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_630912.1"
                     /transl_table=11
                     /translation="MEESRIPGDRGTRASSVGPHKESHTIFTPPKPLAETIPYLIRVGD
                     LRAEERKVSGLKLFRTDTTTRGMTEVIARLAGIEAEVQDLVEIHMETLLGVRFLASEYS
                     TGPVHGGRIDSLGLDENGSPVIIEYKRGTDAGVINQGLFYLAWLMDHRAEFEHLVHVRL
                     GATAASQVLWSGPRLICIAGDFTRYDVHAVREHRRSIDLVRYRIFGSDLLGLETVASVS
                     GAMQVARRVRRQAVAGAAAGAQGAAMRELAGAVDEFLLGLGDGVNRVERKTYRAYQRLR
                     NFACLCPPQRSKLLVYLKVDPKDVDLVPGFTRDVSGLGHHGTGDLEVQLRTPRDVERAQ
                     DLFRASYAAA"
     PFAM_domain     43146..43379
                     /aSDomain="NucS"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01939.19"
                     /db_xref="GO:0004519"
                     /description="Endonuclease NucS"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6841_0930"
                     /evalue="1.70E-05"
                     /gene_ontologies="GO:0004519: endonuclease activity"
                     /label="SCO6841"
                     /locus_tag="SCO6841"
                     /protein_end="152"
                     /protein_start="74"
                     /score="24.4"
                     /tool="antismash"
                     /translation="LAGIEAEVQDLVEIHMETLLGVRFLASEYSTGPVHGGRIDSLGLD
                     ENGSPVIIEYKRGTDAGVINQGLFYLAWLMDHR"
     PFAM_domain     43659..43964
                     /aSDomain="DUF5655"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF18899.3"
                     /description="Domain of unknown function (DUF5655)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6841_0931"
                     /evalue="9.10E-08"
                     /label="SCO6841"
                     /locus_tag="SCO6841"
                     /protein_end="347"
                     /protein_start="245"
                     /score="32.3"
                     /tool="antismash"
                     /translation="AAMRELAGAVDEFLLGLGDGVNRVERKTYRAYQRLRNFACLCPPQ
                     RSKLLVYLKVDPKDVDLVPGFTRDVSGLGHHGTGDLEVQLRTPRDVERAQDLFRASY"
     gene            complement(44153..45517)
                     /db_xref="GeneID:1102281"
                     /gene_synonym="SC3D9.10c"
                     /locus_tag="SCO6842"
     CDS             complement(44153..45517)
                     /codon_start=1
                     /db_xref="GeneID:1102281"
                     /gene_synonym="SC3D9.10c"
                     /locus_tag="SCO6842"
                     /note="SC3D9.10c, unknown, len: 454 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_630913.1"
                     /transl_table=11
                     /translation="MTPAIDAHVRLDTHPTHPSAVQAHLTGTQARVASMALEAAGWSAA
                     ATGVLVLARIDHEEPYWAADAAQHLTAAGITVEITPRLQEAIDEEWTWPNYPMTWCTRS
                     EIREVSNQAQKIHDDIRNGHLLIHAHAHDGHTTVAVGTYLHPGGKSVYLHGEDHLRQVA
                     DTFDSPAEALVAFEKVHAAEMRPGPAPLTDTERAAIAARSVFDATTAKPEPPRREPEAV
                     PVYLADAGDHDALLDSFLDTHGEFEKWRTWSDETTHAIHESQTLRIERVHETQARETAW
                     TVAAYETPVSDRMWHLTATDATPAPVLLNLLNHLADGDGWDTVIGVPVGEKTVTTATQP
                     LTEAGWKHTLTGHGIRWTSPDGQASVRFDPLTAQAPQNPATWTIWAGPGPDRPTWAITA
                     SSHTPSSLLADLSESLAHETGTRQPRPGREHRTRLAASAPAIPAVTSDRPASRSR"
     PFAM_domain     complement(44258..44446)
                     /aSDomain="SPDY"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03771.19"
                     /description="Domain of unknown function (DUF317)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6842_0933"
                     /evalue="2.80E-16"
                     /label="SCO6842"
                     /locus_tag="SCO6842"
                     /protein_end="420"
                     /protein_start="357"
                     /score="59.3"
                     /tool="antismash"
                     /translation="TSPDGQASVRFDPLTAQAPQNPATWTIWAGPGPDRPTWAITASSH
                     TPSSLLADLSESLAHETG"
     PFAM_domain     complement(44558..44731)
                     /aSDomain="SPDY"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03771.19"
                     /description="Domain of unknown function (DUF317)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6842_0932"
                     /evalue="3.20E-10"
                     /label="SCO6842"
                     /locus_tag="SCO6842"
                     /protein_end="320"
                     /protein_start="262"
                     /score="39.9"
                     /tool="antismash"
                     /translation="SQTLRIERVHETQARETAWTVAAYETPVSDRMWHLTATDATPAPV
                     LLNLLNHLADGDG"
     misc_feature    45513..45528
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            complement(45583..46701)
                     /db_xref="GeneID:1102282"
                     /gene_synonym="SC3D9.11c"
                     /locus_tag="SCO6843"
     CDS             complement(45583..46701)
                     /codon_start=1
                     /db_xref="GeneID:1102282"
                     /gene_synonym="SC3D9.11c"
                     /locus_tag="SCO6843"
                     /note="SC3D9.11c, unknown, len: 372 aa. Weakly similar to
                     Streptomyces coelicolor TR:Q9X8A4 (EMBL:AL049645)
                     hypothetical protein, SCE2.09 (386 aa), fasta scores opt:
                     559 z-score: 616.2 E(): 6.5e-27; 37.5% identity in 363 aa
                     overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_630914.1"
                     /transl_table=11
                     /translation="MPHTPEPDEDDLDAIAPPQPVFHAEQALLGALLLDPHRLDDVSGI
                     AADSFSTAAHAALYTALSTLPRPDPAEHAKNTKWLDRVLTAGREQARGLTATYLHSLVQ
                     VCPWPRHAPAYARMVEAEHARRRLLTAAERLIHTVHDASLPLPVQTVLTETDTLAAVVD
                     DIADRFPPRSGVLPRTPAPPPVLAPDHTEAVEEEQLLLATATARPDDIDAVRWLLPDDL
                     TLPLHAGLWQCLTTLARRGEPVDPVTVLWEAQQRGLLDDGCEPGTVLRMLGEPAGSVGH
                     WGEGALQRSLLATAEHTGRRIEAYAGDPANTPFQLVVGARRALADIAAVRTRWQNATRA
                     APPQQRRPAPAIRGGPPTTTAAHAARSTRATR"
     PFAM_domain     complement(45919..46128)
                     /aSDomain="DnaB"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00772.24"
                     /db_xref="GO:0003678"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0006260"
                     /description="DnaB-like helicase N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6843_0935"
                     /evalue="5.30E-09"
                     /gene_ontologies="GO:0003678: DNA helicase activity"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0006260: DNA replication"
                     /label="SCO6843"
                     /locus_tag="SCO6843"
                     /protein_end="261"
                     /protein_start="191"
                     /score="36.2"
                     /tool="antismash"
                     /translation="EAVEEEQLLLATATARPDDIDAVRWLLPDDLTLPLHAGLWQCLTT
                     LARRGEPVDPVTVLWEAQQRGLLDD"
     PFAM_domain     complement(46342..46653)
                     /aSDomain="DnaB"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00772.24"
                     /db_xref="GO:0003678"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0006260"
                     /description="DnaB-like helicase N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6843_0934"
                     /evalue="3.20E-15"
                     /gene_ontologies="GO:0003678: DNA helicase activity"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0006260: DNA replication"
                     /label="SCO6843"
                     /locus_tag="SCO6843"
                     /protein_end="120"
                     /protein_start="16"
                     /score="56.2"
                     /tool="antismash"
                     /translation="PPQPVFHAEQALLGALLLDPHRLDDVSGIAADSFSTAAHAALYTA
                     LSTLPRPDPAEHAKNTKWLDRVLTAGREQARGLTATYLHSLVQVCPWPRHAPAYARMVE
                     "
     gene            complement(46701..47972)
                     /db_xref="GeneID:1102283"
                     /gene_synonym="SC3D9.12c"
                     /locus_tag="SCO6844"
     CDS             complement(46701..47972)
                     /codon_start=1
                     /db_xref="GeneID:1102283"
                     /gene_synonym="SC3D9.12c"
                     /locus_tag="SCO6844"
                     /note="SC3D9.12c, possible DNA methylase, len: 423 aa.
                     Weakly similar to Salmonella infantis
                     SW:MTSI_SALIN(EMBL:J03391) modification methylase, SinI (EC
                     2.1.1.73) (461 aa), fasta scores opt: 244 z-score: 269.9
                     E(): 1.3e-07 24.5% identity in 355 aa overlap. Contains
                     2xPfam matches to entries PF00145 DNA_methylase, C-5
                     cytosine-specific DNA methylase."
                     /product="DNA methylase"
                     /protein_id="NP_630915.1"
                     /transl_table=11
                     /translation="MILDLFAGPGGWSRAVHVLGMRDIGLEWDQWACKTRAAAGQLTIR
                     CDVARYPAWPFIGRTRGVIASPPCQAWSMAGKRLGLVDQPLVHAAVEDLAAGRDTRERL
                     LSACRDERSLLAAEPMRYLYALNTVGEPDWVAMEEVPDVLPLWKQYAAVLRRWGFSVWY
                     GILNAADFGVPQTRKRAILLASRVRTAQPPTPTHAQLAEPESLFGPGRARWVSMAEALG
                     WGATDRPVPTVCAGGGPGGGPEPFPSGSRKTLSDARKRGTWMPRPDRGVLQSCREGTGW
                     AARHRIRESRAADAPAPTFTAEPHRWSWSLRSNNQANATVRSIQEPAGTLFFGHRANEC
                     TWVAEPATPPAEEAEVPAVPEPIRITAREAGLLQTFPADYPWAGNKGQQFSQIGNAVPP
                     LLAGHLLAPHLGVALDPDDFTLAA"
     misc_feature    complement(46740..46883)
                     /gene_synonym="SC3D9.12c"
                     /locus_tag="SCO6844"
                     /note="Pfam match to entry PF00145 DNA_methylase, C-5
                     cytosine-specific DNA methylase, score 33.40, E-value
                     2.2e-08"
     PFAM_domain     complement(46755..46958)
                     /aSDomain="DNA_methylase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00145.20"
                     /db_xref="GO:0008168"
                     /description="C-5 cytosine-specific DNA methylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6844_0938"
                     /evalue="5.30E-08"
                     /gene_ontologies="GO:0008168: methyltransferase activity"
                     /label="SCO6844"
                     /locus_tag="SCO6844"
                     /protein_end="406"
                     /protein_start="338"
                     /score="32.7"
                     /tool="antismash"
                     /translation="ECTWVAEPATPPAEEAEVPAVPEPIRITAREAGLLQTFPADYPWA
                     GNKGQQFSQIGNAVPPLLAGHLL"
     PFAM_domain     complement(47403..47645)
                     /aSDomain="DNA_methylase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00145.20"
                     /db_xref="GO:0008168"
                     /description="C-5 cytosine-specific DNA methylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6844_0937"
                     /evalue="2.30E-08"
                     /gene_ontologies="GO:0008168: methyltransferase activity"
                     /label="SCO6844"
                     /locus_tag="SCO6844"
                     /protein_end="190"
                     /protein_start="109"
                     /score="33.9"
                     /tool="antismash"
                     /translation="DERSLLAAEPMRYLYALNTVGEPDWVAMEEVPDVLPLWKQYAAVL
                     RRWGFSVWYGILNAADFGVPQTRKRAILLASRVRTA"
     misc_feature    complement(47421..47501)
                     /gene_synonym="SC3D9.12c"
                     /locus_tag="SCO6844"
                     /note="Pfam match to entry PF00145 DNA_methylase, C-5
                     cytosine-specific DNA methylase, score 17.60, E-value
                     0.00051"
     PFAM_domain     complement(47724..47969)
                     /aSDomain="DNA_methylase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00145.20"
                     /db_xref="GO:0008168"
                     /description="C-5 cytosine-specific DNA methylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6844_0936"
                     /evalue="4.60E-07"
                     /gene_ontologies="GO:0008168: methyltransferase activity"
                     /label="SCO6844"
                     /locus_tag="SCO6844"
                     /protein_end="83"
                     /protein_start="1"
                     /score="29.6"
                     /tool="antismash"
                     /translation="ILDLFAGPGGWSRAVHVLGMRDIGLEWDQWACKTRAAAGQLTIRC
                     DVARYPAWPFIGRTRGVIASPPCQAWSMAGKRLGLVD"
ORIGIN
        1 agcatcagtt ggacgagcgg cactacacag atgagcagac caccacgaag agcagcccat
       61 gggaacgcgc actcgctgcg gtctacggtc ccagcaggag caggcttctc gtcggctagc
      121 ggtattgcgt aagtgacccc ctgaatagcg gtgatgatgt catcttccga acggagatgg
      181 agggagatcc ggaatcacag ttctttcgtt gcctggggtg cagggtccag gatggagcgg
      241 atccggcgca gtccttcgtg gttgacggag aaccaggccc aagtaccgcg ccgttcccgg
      301 tccaggagcc ctgcttcagt catgatcttc aagtggtgac tgacggtgga ctggcgcagc
      361 cccagactgt cggccagatc acagacgcag gcctcgccat cgggggcctg ttccaggagt
      421 cgaaacaatt gcaggcgggt ggggtcggcg atggatctca gtatcgtgga cagctgttcg
      481 gcttcggatc gctccagagg ctgacagttc agccctggcc cgcacgagcc accttcgagg
      541 aacccgtcat ccgacatctg cagatctatg acagtcaccc gtcaaccata gacgcagggt
      601 gatcaccttg acacgatcga atatggccgg actgcgagtt cacctgatgt tgggcagccg
      661 ctaggacagg cggcctccgc gtcggtcctt gttggctatg gctttctggc agccggagtc
      721 ggtgccgtgt accaggcgat gagcgctgcg gcggccgagg ccaacgcgag agcggagaac
      781 aggcgggggt agccgccgag aggtgcggcc agggcggtgc cagcgaacgg agcgagtgcg
      841 gaggcggtcg tcgtgggggc ggcgagaagg ccggagaggc ggccgtagcg atgggcgccc
      901 catcggtctg tgatggcggt ggcctgcagc agggtcaggt tgccgcggac agtaccggcg
      961 atgacggcca gcgccgcaag cagcccgtag ggtccgggaa tgagcgcgaa ggctgcggtg
     1021 gtcacccctc ccatgccgat cagcactgct gcgcgcagag cgggggagct gcggcgggct
     1081 agtggggcgt agagggtgcg gccgagggtc tggccggctc cgcccagccc cagagcccag
     1141 gcggcttcgg cagcggtgta gccgcggtcg agtagcaggg ggacgagtgt gatgacgacg
     1201 gcgtatgtcg cgaacgccga aagagtcaga gccgttgcca gaagaaggaa gggacggcta
     1261 cgtgtgatga cggtcgtaga cgcggtctca cctgttgtgc ttgggggcgg ggcggggggc
     1321 catgggccgc gcagtgcgta ggcgtggacg ggcaccgtca ctgtggccag gacgagagcc
     1381 agcagcaggt aggtgtgccg ccaactgaag tggttggcca actgggcggt gaggggtgcg
     1441 aagacggtcg atgccaggcc gccggcgaga gtgacgatcg tcagcgcacg tacgtggttg
     1501 ggggcccacc agcgggtcaa tgccgcgaag gcgggctggt agaaggtgga ggccatggcg
     1561 aaccccgcca gtagccatcc ggcggtgaac acggtcaggt tgggggcgct ggcgatgatg
     1621 accaagctga ctgttccaac caccgaaccg acggtcatga ctgtgcgagg gcctcgggca
     1681 tcgaggatgc ggccgatgcg aatgccggca acggcggaca tcagcaaggc agcggagaac
     1741 gcggctgtgg tcgcagtggc gctccagccg gtggccatgg tgatctgtgg attgaggacg
     1801 ggaaaggcgt agtagacgat gccccagctg gtgatctggg tcagacacag ggcggggagg
     1861 gccgcccgcg gccgcgtcgg ctggttgagg gcggccgcgg gggaggccat ggagcggtag
     1921 ctcatgcctt ctcagcaaca actggttgtg gtggcctgcg gtcccggttg gacggcgtcg
     1981 gtgggtgcgc aacacgtgct gccgggttgc ttggctaggg tgtcggcgtc cgccttcacg
     2041 acgtacacct cccacgcctc ctgaccgggg ccgtgcaccc acaccttgtc ctgcagggcg
     2101 tagcagcacg cggtgtcgtt ctcttcgcga gtgctcagcc ctgcctggct cagccgggcg
     2161 gtggctgccg cgacgtcctc ggtggatgcc acctcgacac cgaggtggtc caggcgggtg
     2221 tccgtgccct cttctccctc gatcagaacg agcttgagcg gcggctcggt gacggcgaag
     2281 ttcgcatagc catcacggag cttggcaggc tcggtgtcga ggagtttgct gtagaaggcg
     2341 atggctgact gcaagtcggg aactcgcagg gcgagttgta tccgtgacat ggggcattcc
     2401 tcctgccggt tcagtggtgc aggctcccgc ggccgcaacg gctgcgggtg gggacgatca
     2461 ggcgttgcag ctgctgccgg gtgtcgtggc cggtccggga gagatggtgg acaactggac
     2521 cagctgcgga gcggacggag cgcagcagcc ttccttttcg ggctcggcgg cgccgtccgt
     2581 gtcgaagagt ccggagcctc cgcacacgcc ggtttccggc aggaccagtt cgacgcggtc
     2641 ggcagcttcg gtttcgccgg ccagggcggc cgcgatcgag cggacctgct cgtagccggt
     2701 catcgccagg aacgtgggag ctcgtccgta gctcttcatg ccgaccaggt agacaccgga
     2761 gtccgggtgg gacagttccc gatggccgtg cgggtagacg gttccgcacg agtgctggtt
     2821 ggggtcgatc agcggagcga gctcgaccgg tgcctgcagg cgctcgtcca ggcgcaggcg
     2881 gacctcggag aggaaggaca ggtcggggcg gaaaccagtc aggacaatga cctcgtccac
     2941 tgcctggagc cgtcgtccgt cctccgcgac gaggatgagc cggtcctcag caccgcgttc
     3001 tacggcctcg gtgcgaaagc cggtgaccgc ctcggcgtgg ccctcatcga cggcggcctt
     3061 ggcagccaga ccgagggcac cgcgtgcggg cagctggtcc gcttcaccgc cgccgtaggt
     3121 ggagcccgag aggccgcggc gcagtaccca taccgtcttt gtcgttgcgc tgttctgcga
     3181 tcgcgcgagt tcggccagtg aggcgagtgc ggtgaatgcc gaggcgcccg agccgatgac
     3241 cgcggtgcgc ttctccgcgt agcgtgcgcg caccgccggg tcggtgaggt cggggacgcg
     3301 gtaggtgaca tggtcggagg ccatgtgctc gccgagggcg ggtagaccgc tgctgccggc
     3361 gggggagggc agggaccagg tgccggaggc atcgatcacc gcagaggcgg tgatcctttc
     3421 ttcccggccg tctgtgtgct tcacctggac gacgtacggc tgtgcgtcgc ggtcggcgtc
     3481 cacgacgcgg tcccggccgg ccttcgagac gccggtgact cgggctccgt agcggatctg
     3541 gtcgccgagg gtgtcggcaa gcggctgcag gtagtgcttc acccagtcgc cgccgctggg
     3601 gtaggtgctg ctgtcgggcc tgctccaccc ggtgggggtg aggagctttt cggcggcggg
     3661 gtccacgacc tcgccccagg tggagaacag gcggacgtgt gcccactcgc tgacggcgct
     3721 gccggcggtg gggcctgctt ccagcacgag cgggcgcaga ccccgttcca gcagatgagc
     3781 tgcggcagcc agcccaatgg gtccggcgcc gatgacgact acgggcgggg tgaggacggc
     3841 gggcgcagtc acgatgactc ctcggcttcg atgtttgtcg atgccgccag catgcatccg
     3901 gaatcgacat ccgtcaacat agaagttcat ctattctgtg cccgatcggg cgcagagggg
     3961 ttccgcttac tgcttggcaa atgattagat gcctgtcaac atagaggcat gtcgaatctg
     4021 gctctggact ccaccaacgt gaacgccacc gggtcctggt gctgccagcc gctgggcaag
     4081 gaagagctgt ccgctgcgga ctcggaaaag atcgccgtga tgttcaaggc gctgtccgat
     4141 cccgtccggc tgcggctgtt ctcgaagatc gctgctcggc cgggcggcga ggcctgtgtc
     4201 tgtgacattc aggatgtcgg agtctctcag cccacggtca gccaccacct gcgcaagctg
     4261 agagaggccg gacttcttga gtcggagcgc cgtgccagtt gggtgtacta ccgagttgcg
     4321 cccggcgttt tgtcggccat ggcgggactg ctgtcgcaga ccacctgaac cggtcggctc
     4381 tgctcgttcg caggtgtgcg ctcggaccgt gtgctgcgac cccctgggtg ccaggacatg
     4441 cccaccggta acggatccca gaagggacgc tgggagggag atgtcatgtg tcagaaaggg
     4501 gcgggctccg cttgtgacgg gacgtgtctg gagctgactg cggccgacat ggtctggtgg
     4561 tccaatgtct tcaagaccct gggagatccc gttcgtctgc agctgctgat gaagctcgcg
     4621 gagcggtcag ggggtgaggc cgcggtacat gagctggcgg acgtcggggt gtccccggcc
     4681 acagtcagcc atcacctgaa acgactgcgc tgtatcggcc tgatcgagag caggcgtgac
     4741 ggtcgccttg tctactacaa gctgggtgcc ggtgtgcgcg ctgcgctgat gcagatcctg
     4801 catcagcgca gccaggtcgg cgcgtaggta tcccgccgtc ggggccgggg ccccgcctcc
     4861 gagcggtgcg gtgaggtgca acgacgcgag gtgcggcgtg gtcgagaagc tgtgggcgtt
     4921 ggcagacctt cgtccaccca cgggcgatca gcccacggcg gcaggtgtgg atgccgtcac
     4981 gggttggtcc aggtggacgg tcgtatcgca caggcgttcc acctgcgccg ggtcgtggga
     5041 gaccaggagg acggcacggc ttccgcgcag cgccgaaatg gactgttcga ccttgtccct
     5101 gctgcgttcg tcaagggcgc tggtgggctc gtcgagcagc agtccggccg gctccagggc
     5161 cagagcccgg gcaaggcaga gtcgttggcg ctgccccgcg gacagattct gcgcgggtga
     5221 gtcgagccgg tcggcgacct ccttccacag tccggcttcc tccagcgcct tctccgctcg
     5281 ctcgcgcagg acctcctggg aggcgcggag aagatggcgg agcccgaaca gggcgttgtc
     5341 gagaatgctg cccccgaaga cgacaggcgt ctgaggcaca aggacgatct tcgacctcag
     5401 gtcggcgtct cccttgccgg gggcgatcgt gcggtccagc acctgcagtt ccccatcgcg
     5461 ggtcagtccg ttggggagca gttccaccag ggcgcgcaga accgtggatt tgccgacccc
     5521 ggacggtccg cacaggcccg tggtcgatcc gtgcttgagg ctgaaggaga cggggccgac
     5581 aaggtttttg tccctgctgc gcacgcggag ttcgcgcacg gtgatcacgt tgtccatcgt
     5641 tccccctcaa agcggttgcg cagcgcgacc gccgcgctga gaagtacggc tgtgatgatg
     5701 accagcacca tggcgcttcc ccatgcctgg gtgacggcct gtgggtctcc cgagtcctgg
     5761 gagagcgtga agatgtgggt cggtagtgcc tgcaccggcg cttccacgat gccgctcggt
     5821 agggcgggtg cgccgaagaa gaccgtcgca gtgaagatca acggggcggt ctcgccggcg
     5881 gcgcgggcca gtccgagcag cagtccggtg atcgttgcgg gccaggtgta cggaacgacg
     5941 actgagcgga cgaactgcgc gcgcgtcagg ccgagagaca tggcgctttc cttgagttcc
     6001 ggggggatgc tcctgacgcg ggcggatgtc gtcagggcta tcaccggcac cacgacggga
     6061 acgagtacga tcgcgccggc cagccacgac cggccccagc ccatgctggt ggagaggatc
     6121 acgaatccgg cgaggcccag caggatggtt ggagcccctc cgaggacgac agtgaaggtc
     6181 tgcagcactc gcgcggtgcg ctcggatgcg tggacgccga tcaggatgcc cgcaccgaat
     6241 ccgaggggca gggccaggat gccggtggcg aggataagga gcacggtgcc gacgatctgg
     6301 tcgcggacgc ctccgcctgc cgcgcccgtc gctgatgaga accagaaaga cggattgaac
     6361 gccgagctcc ctcgcgtcac cagtagaccg agcatgccga ggaggagggc actgggtagg
     6421 agcagggcgc ccagccgcag cgtcatgacg agccggtccc gctgcaaccg catccgagat
     6481 gtcccccgga agcgcggagt gcgtgccgcc gcgttcttgc gggtgcgact tcgggtaccc
     6541 cagatggtcg cggcggccac cagcgccagg aggatgagac cgagtgcgca cagcgcggcg
     6601 aagtaggggc ctgaggtccc ggcgaggacg ggctccggac cggcgagttt cgtcgtcaga
     6661 gtctggccgg ggtgggacag cgagtcgagg aaccccccga aactggtggg cagtcgtccg
     6721 tctgcccggc cgacgaccag gaagacggcg atggcttcgc ccagcgctcg ggccagtccg
     6781 agcagcacag ccgctcgcat gccggaccgg gcaagcggca gtactgccga gcggactact
     6841 tcccggcggg tcaggccgag ggagtacgcg gactcgcgga cacggtccgg tacagcagcg
     6901 agtgcgtcga cgctgaccgc cacgatcgtc ggagtgatca tgacggcaag gacgatgccg
     6961 gcggcagcga gactgtcgcc gccgggtacg tcggcgatct gcgcaatgac agggcggacg
     7021 accatgatgc cgatgaggcc gtagacgatg gacggtacgg ctgcgagtag ctccacgcac
     7081 atgcgtagtg gccgggacag acggggcggg aggtactccg acagtgcgac ggctgcggcc
     7141 caactgatcg gcacggcgat gaccagcgcg agggcggaca ccacggcggt tccgtagatc
     7201 attgccaggc cgccgtacac ggagcttgtc gggctccatg ccttttcggt cagcagttca
     7261 agccagttga cgtgtccgct ggccagtcct gcgccgagat atccgatcac ggtcaggagc
     7321 agggccgcca cggcgaaggc cccgccgtag agccaactcc agatccattt ggaggcgcgt
     7381 gggcggctgc cgacctcggg tgcgacgggc ggccgtgtca gggtcttggt ggtcatcgac
     7441 tacttcccga tttccttgag ggtcaggtag tcgtgcttgg tcatcaaggc ctggcccttg
     7501 gcggagagta cgtagtcgat gaacttcttg gcggttccct ccggcttgcc gtcggtgatc
     7561 aagtacaggg gacgggacat ggggtacttg cccgtggcga tgttctcggg tgacgcctct
     7621 attccgtcca gcgtgaccgc ggccaggcgg tcgcgtccct cgacgaagct ggtggacagc
     7681 ggtgccacgg ccccaggcgt ggactccagc ttgttgcggg tctccaggtt gccgccgacg
     7741 atggcgaagt tgccggactc aggcggcggc ggggccttct cgtccccgta gatgtacttg
     7801 tcgaggacct ctcgcgtgcc tcgccccggc tccttgtcgt agacgaagac gtcgagatcc
     7861 gggccgccga cttccgacca gttcttgatc ttgccttcga acaggtcacg cacctggtcg
     7921 gcggtgaggt tcttaacccc ggcgtcggcg acctgcttgg tgacgatgat gccgacggcg
     7981 tcggcaccga tctgtgtgga gacgaagtcg gtgtcggggt tggcggcctt gtcctcctcg
     8041 gacaggggct tcgagctcag ggcgatggtg atctgcccgg aggcgagctg cgagatgccg
     8101 ccggccgagc caccctgggt ggcgacggtg atgtcgagtc cgtcggcctt gagtgcctcg
     8161 gccgcgtcgg cggcgaccgg agccacggtg gtggacccgc tgacctgcag cgcgccactt
     8221 tttccggccc cgccgtcggc gcaaccggcc aacgacacga ccgccagtac cgaagttacg
     8281 aggcatgcga ggcggcgctt cttgctgaac atttctgagg cccttccttt gcgcgtgacc
     8341 gtggtacttg gggtgtaggg agacagggcg cgatgcgacg ccctcaggac ggtcaccggt
     8401 gtgacagacg aggaaggacc gggctggtag gtggactgtc cctgtcagtc atgccaatgg
     8461 cagacggagg ggtgtcccga gtgctgggtg gggcgtggac gaacgctgag tgcgtgcagg
     8521 cgtgcatgtc agatccttcg gggttggcgg tgccctgaaa gagaacgcga ggaatctccc
     8581 gtgggagggt tgctcgcgca ggctgcgggg ggatctggtg gcgcggccct cgctatgtgg
     8641 tggtggtcag ccagacggtg tcggatgcgg ccaggtggag gtgcaggccg tcggctgctt
     8701 cgctggtgtg catggagccg ctgaggaagt gccaggtgca gtgggcgtgt tcgggcagca
     8761 gggcgcggag attgacgcgg ctctcggtca tggacgggtt gtgcaggccc agcaccgctc
     8821 gcgagcggtc ggcgggctcg tgcagtactc cctcgatgcc gtcggcctcc agctcgcgga
     8881 cgagagcgtc ccgggcgaag gcggccgcga tgtggggctg cgtcaggcag tcggacaggg
     8941 cgggagttcg atgccacggg gcgtggtcgg gtgtgggggt gagtggactc acagtagggg
     9001 ccttcctgtc atggcgggtc cgggtttgtg tcccagtagg tgcaggatgg tgggggccac
     9061 gtcggccaac gtggccgttc ccggcagcgt gggtgccggc gtgtcggtcc ggtttgggac
     9121 gatcaccagc gggaccgggt tcgtcgtgtg gccgccgtag ggccgtacgc tgccgtccgg
     9181 agcctgcttg gtcatgcgtt cggcgttgcc gtggtctccc acggccacta cccatcggcc
     9241 gctgttccgt gccgcttgca agatctggtc cacggcggcg tcggttgcct cgcaggccgt
     9301 gacggtggcg gcgaggtttc ccgtgtgccc gaccacgtcg atgttggcca gattggcgat
     9361 gacgaggtcg acatcgacgc ggccggcggc ctcgactacc gcgtctgtga cgcggtcgag
     9421 gttcatgtgg ggatgggcga cgtagtcggc cttgccctca cctgtgatcc gcacatgctc
     9481 ctcgccgtcg cgtacggtcg cgtcccggcc gttgatgtag tacgtgacgt gttcgaactt
     9541 ctcggtctcc gcgatgcgga cactgcgcag cccggcttcc tgcagctcat cggccagacc
     9601 gccggaggcg tccgcgcgct tcacgagggc gggtatggcg gtgcgggtgt cgtactgggc
     9661 caggctcacc atgttcacag tgcggccgct ggctgtgagg tgctcatgga gcctgtccgc
     9721 gaactgctgg atacggtcgc tgcggaagtt gaaccacagc accgcgtccc cgtcggcgac
     9781 cctcgcgtca cccgcctccg tgagcacgga ggcggggacc cactcgtcgc cccgttcgct
     9841 tgagtggacc gccgagtggg cactgtcggc cggggagccg cgcccgtcgg cgaccagggc
     9901 gaccgcacgc tcggtcaggt cgagatcgcc ggccttgtcc atcgcgtagc cgcggccgat
     9961 gactgtggcg atctgcccag ttccggctgc ggcggccaac tcggccaccc gtgtcagata
    10021 cgcctcgccc gtgtggtcgg cgacatcccg gccgtcggtg atcgcatgga tgaagacgcg
    10081 ctccacctgg tgcgtggctg cggcggccag cagctcgctc aggtgctcga cgtgggcgtg
    10141 gatctgcccg tccgaacaca gaccgatcag atgcagcgcg cctgaagtgg ccgcgacctc
    10201 gttcagcacg gcgtccagcc gcggatggct gcgcagggcg ccgctgtcga tggcctgctg
    10261 gaccaggagg ctgtcgtagg ggaggggcct tccggctccg atgaccatgt ggccgatctc
    10321 ggagttgccg accgtaccgg ggagcagacc gaccgcttca ccggaagctt cggccagcgt
    10381 gctcgggtgc tgggccacga gttcgtccag caccggggtg cgggcgaggc tcagggcgtt
    10441 gtcgtcggcc gcgtcggcgg agccccagcc gtcgaggacc aggaggatgc ccgggccggc
    10501 gagcaccggt tcgggtgtgc tcacttggtg ctctccaggt ccgggtgcag ggtgtcgagg
    10561 gtctgccaga aggcggggaa ggacttggca acgcatcccg ggtccttgat gaccacgccc
    10621 tcggtgcgca gaccgccgat ggcgaaggtc atggcgatgc ggtggtcgtc gtaggtgtcg
    10681 atgaccgcgc cgtgcggagt gccgccggtg atgtacatcg cgtcggagtg ttcctcgacg
    10741 tcgatgccca tcttgcgcaa ttcggtggtg acggcggcga tgcggtcgca ctccttgacg
    10801 cgcagggacg cgatgttggt gatccgggtg gtgccctcgg cgtacgcggc gacgatggcc
    10861 agtgagggca cgacgtcggg catggcctcc atgtcgatgt cgatgccgcg caggggacct
    10921 ccggtgaccg tgatcgagtc gtcgcctacc tcggtgcgac agcccattcg ctccagggcc
    10981 tggacgaggt ggacgtctcc ctggtgggag ccggcaccga tgcccggaat gacgacgcgc
    11041 gactggagga tggcggcggc cgccaggaag taggacatgc ccgaggcgtc cggctcgacg
    11101 gtgacctggc cgccgcgggc ctgctgaccg gacgggacgg tgaagcgtcg gtagccgtcc
    11161 cggtcgacgc tcacgcccat ctccgccagt ccggcgagcg tcatctccac gtagggcttg
    11221 gagaccaggt catcgctgat ggtgatctcg gtgtcggtct gggcgcgcag ggcgttgatg
    11281 atgagacttg aggtgaactg gctggagacg gctccgctga tggaggtggc gccgcccttg
    11341 aaggagccgc cgacgacgcg gactggcggg ctgccgttgc cgcggaccgc cgtggcgtcc
    11401 acccccagtg ccggcagtgc cttgagcagg tcgcccatgg ggcgctcctg catgcgggca
    11461 ttaccggtga tgatcgtcgt gccgtcggcg tggcctgcca tggagatcag gaaccgcagc
    11521 ggcgtgcccg cgccaccgac gaagatgtcc tcgctcgggg cgcgcatcgg cctgcccgtg
    11581 ggggtgacgc ggatgcgggc ggtggcgtgg tcgatgtcgc aggtgacgtg accgaaggtc
    11641 tcgatggcgc gggagaagta gacggtgtcg tcagacaaca gcgcgttgtc gatgaccgtt
    11701 tcctgcccgg acagcgaagc gatggcgagg taacggttgg tgtagctctt ggatcccagg
    11761 acgcggactg tctcgtcgaa accggtgagg gttcggatcg tgagggtctc ggccttgagc
    11821 cgtggatcgg gcgttgcgga catgcgttac ctcctgcagt ggggacgggt gaggtgatgc
    11881 ctgtgctcgg tgatgcgtca ggctttgacg acccggcagg cgaagcactt gaaggcctgc
    11941 tggccggaca ggttgtcgta gaagcggtcg tcgggcagtg tgttggccgc ctcgtagcgg
    12001 gggtcgtcga agaggtcacc ctgcttttgg gctgggccga aggtgttggg gacgaacacg
    12061 gtgtccgctc ggatcccctc ccagaggagt gcggtaccgg taaccgatcc gcgagggctc
    12121 tcgacggtca cctcgtcgcc gtcggcgatg ccggaccggc gtgccgtgtc ggggtggatc
    12181 tggatgaagc ggatgccgtt gagctgcttg cccgtgggtg tccagtgggt cacctcggcg
    12241 aagtggacca cgctgggccg gcccgtcatg cccatgagcg ggaagtcatg gtgcaccgcg
    12301 tcgcttcccg ggactcccag gcgtacggga tgggtgactg cctgggggtt gatggggttg
    12361 gtgacgaact tgcgactgta ggacagggtg gggttcctgc ccgtgacctc gggatgtgtg
    12421 tagaagatcg gaagggcgct gtgcccggtg accgccagct tcttctccag gtccggtgtc
    12481 gagatctcga ccttgccgct gggggtgagg aagcgtttgc ctcggttggc cgggtcgagt
    12541 gactcggccg cctggtacca gctggggtgg tccaggtaga gggtgctcac gccggggtgg
    12601 tcctcggtgg ggcacggcca gcgcagcggc tcggtgcgct gtcgcatcct tgcgcgggtc
    12661 attcctccca cgccgggggt gtgggtgacg aaggcgtccc acagttcccg gtagttcatc
    12721 caccgctctg ggaacgccgc acgccactcg gcggctggcc gacggctgtc gagttcggcc
    12781 agcgcgtgcg cgagcccgac ccagatctcc cagtccggcc gggattcgcc cactcggtcg
    12841 acggcctggt cctgccagcg aatggctcgg tcgtcgcggc gcatgtagac gccttccatc
    12901 tccaggccac tgcagaccgg caagatgatg tcggcgtagt acgcggcctc ttccatgaac
    12961 aggccggtgt agacgtagaa gtcgagttgc tcgaacgcct tcttgacctt ggtcgtgttg
    13021 gccgaggaca ccagcggatt gccctgggtc accaccgcgc gcagtcggta gggattgtcc
    13081 gtgaggatgg actcggcgaa gtagtccggg ccgaccggca gcgcctcgcg ccgctcgggc
    13141 aagtcggcgt ccaggggtgg caactgcagg tcgccgggcc aggtgttgtg catgaagttg
    13201 cagccgccgc cgggctgccc gatgttgccg gtcaccgcag caaggaacgt ggccacccgg
    13261 taggtgtcga aggcgccgag ctggtgggag attcccgcgt tgcagaagat cgctgccggt
    13321 ttcgccttcg cgtattccac cgccatcttg gtgatgacat cggccttgac tccggttacc
    13381 tttgccgccc actcgggggt gtactggtgc ttcgcgaggt gccggcgcag ctcgtcaaac
    13441 cctgctaccc agcgtttgac gaacgccttg tcgtacagct tctcctgcac gatgtggtgg
    13501 agcatggcga gcaggagcgc gaggtctgtg tgcggcttcg gcgccaccca gcggtcggcg
    13561 gctgctccgg tgggcgtcag gcgcgggtcc acgaccgtca gggtcgcgtt gttctccttg
    13621 cggccgcgca ggaggtagtc gaaggtgacc gggtgtgtct cggcctggtt ggtccccagg
    13681 aacaggtagt ggcgcgctga gccgaggtcg tccttgccgg tcgagccgtc ggttccgtag
    13741 ccgttggtga agttgccgag tccgaaggtc atcgcgaggg cgttgccgcc ggcgtcgttg
    13801 cagaccgggc cgacatccgt gttgttgggg ctgcccagca tggcgaacat gcgggccacg
    13861 agagatccgg tgcctcgggg catccggccg gtggtgcggt tggcgatggt gtgggcctgg
    13921 cctgcatccc gcagcgccag gaacttcttg gcgatggtgt gcagggcctc ctcccagctc
    13981 acggcctcaa acttggagtg cggagagccc ttcgcaccgg agacgcggcg aagtggacga
    14041 gtcagccgct cggtgttgta gacgagctgt ggcatcagct cggctttgac acacacctgc
    14101 ccctgctgga ccgggtcgct gtcctcgcct cgcacagcca gtacacggcc cgctttgagg
    14161 tcgacgttga gtcggcagtt ggaattgcag aactggcagg cggtggcgac tgtcttgtca
    14221 ggggtcaagg cggcggactg gtcggtgaaa tccgcgccgg accctccgcc cgtaccggac
    14281 ggctctcccg gggagcctga ggcgtcggcg gcgcgtgcag agaccaccgg aagcaggacg
    14341 ggcgttccaa ggcctgcacc gccgacgacg ctcccgcgga cgaaaccgcg ccgggacagg
    14401 ccgtgctgat cgtgcttcat gaagacgtgg ggatccttcc gcctggtgtg gggtacgagg
    14461 cgggcatggc ggtgcccggg ccgtgcgggc gtgccgcacg gccttgtcgg atacggatgt
    14521 gccgtggtgg tcaggtcgtg ggcatcggca gagcgtcggt gtcggccttc gcgcttacgg
    14581 cggccagaaa cgccttgagg atcttgtgtt cgcttcccgg agcggaggag agctcgggct
    14641 ggaagaggct gcccaggaag aaggggtggc cggtgatctc cagggcgcgc ggtgcgccgt
    14701 cgctgtccca ggcgctcagc ctcagtgagc cctggttggc cgcgttcatg aaggtgtcgg
    14761 tcaggccgta gtcgcagtgg aagatctcct cgacctcggt cgtaccgtag atgccggcca
    14821 gccgggagtt ctccatcacg gtcaagggag ccttctctcc gcggaaggag cacttcagcg
    14881 gcgtgacaag aggcatcagc ttctcggggt cctcgtcgac gccggccgcc tccgggaggt
    14941 ggagcacgtt ctgggcgtgt tcgatcaggg cgctgaagaa gccaccgcag gtgcccagga
    15001 agggcagccc gttctcacgg gcgtggcgca cggcgacgtg cacgcccttc tggttgaagt
    15061 acggggctcc cggcacgacc catatgccgt cgaagccgtc gagaaccgag acgtcgtgta
    15121 tgtcggtggt cggtatccac tcggtggtca ggtcccactg ctcacgcatc gcgtcgatct
    15181 tcgggtggga cggctcgtcg tgattgccgc ggtctcccac cagggcaagg cgtggccgtg
    15241 cagagactga catcgttttc cccttcaacg gttcaggagg gcgaatccgt ctcgccagtg
    15301 acggttccag cccaaggggc gcggcagagc gcgtgccgtg cgttctgctg cgcgggtgtg
    15361 gtcgtgcctg aggtgatgtc aggaccgtgc cgccacgcac gggtcccgtg agaaaggaaa
    15421 gtggggaact accgccgtgt ggacggccgg gctgggagtt gttgcctacc ggatgtacgc
    15481 atgtctgcca gccccctggt gtgccccgtg tgggagccct ctgcaggccc cccgtgctgc
    15541 ttctcgctca atttatcgat ggcggtcaaa gtattcgagg gtttccgggt cggcctggaa
    15601 acgatcacgc catctccgtc atttgacggg actgccgctg tgtcggctgt caggggcggt
    15661 aaggaggtgt tctgaccagc cgtctcggtg gcactccggt ggccgcggac cggagggggt
    15721 ggcgggagtc ccgctcggcg gtgatccgtc accgtgagtg cttccgtgca cgccagtgcg
    15781 gtgaacggaa cctgccctgc cggatcgtgg gaggccgcgc gagttggccg gatccggcgc
    15841 acaaaccagg ccgttattaa cagtgatgac tgttgatagc gatggatgct gtttagtttg
    15901 ggcttggctg atggccggcc tgctcgtcat tcccccgtgc gacggccggc cacagccgct
    15961 ccccgggact ccaacctgtt gcgtttgagg agaagcaagt gaacagctcc gccggccatc
    16021 cgcgccgatg gcagatcctg aacatcctgt gcctgagtct cgtgttgatc ggcctggaca
    16081 ccctgatcct gaacctggcg ctgcccagca tccagaagga cctggacgcc acgagcagcc
    16141 aactgcagtg gatggtggac tcctacgccc tggcgttcgg cggactgctg ctcatggccg
    16201 gcggcttgtc ggaccggttc ggccgcaagc ggcttctctc cgtcggtctc ggcgctttcg
    16261 ccctgaccag cctgggcgct gcgttcgcct ccaacgccga gatgctgatc actttccggg
    16321 ccctcatggg catctcggcg gcactgatga tgcccgccac ccttgccatc atcaaggatg
    16381 tcttcccgcg cgaggagcag ggcaaggcga tcggcatctg gtcgggcgcc gctgcggtcg
    16441 gcgtgccgct gggcccgctc gtcagtggtc tgctgctcga acacttctgg tggggatcga
    16501 tgttcctcat caacgttccc ctggcggcca tcgccctgat cggcggagcc aagctcatcc
    16561 ccgagtccaa ggccgaaggc caccccggcc tggacctcgt cggcgccctt ctctcggtgg
    16621 cggggctggt ggccatcgtc tacggcctgg tcgaagcccc gcacaacggc tggggcgaca
    16681 tcatcaccct cggctccctg ttcgtcggcg tcgtgctgat ggttgccttc gttctgtggg
    16741 agcggaagac ggcccatccg atgctcgacg tcggcctgtt cctgaacgct cgctacggcg
    16801 gcggcgcgct ggccatcgcc tgcacctcct tcggcctcta cagcggcctg tacctgctca
    16861 cccagtacct gcagtcggtg ctcgaactcg accccctggg cgcgggcctg cgcatgctcg
    16921 ccatcggcac gatgatggtc ggcgcgccgc tgtccgcgaa gctggtggag cgcacggggc
    16981 tgaaggcgac ggtggtggtc ggcctgctgc tgtgtgctgc gggactcggc gtcctggccg
    17041 ggctcagcgt cgacgacgag acgcaggccc tgatcggcct ggccgtgttc ggcctcggta
    17101 tgggtatcgc gctgccggcc gccgtggatg ccatcctggt ggtctccgcc gcccgtcagg
    17161 cgggcgccgg gtctgccgtc gccgatgtcg gcatgcaggt gggcggcgcg ctgggcatcg
    17221 cgatcagcgg cagtgtgatc gccacgctgt accgtgacga cctgccgcag gcggctcaac
    17281 tgcctggtga ggccggagaa gcggtacacg agtccctggc gggcgcttcc gcggtggccc
    17341 agcagctcgg cggcgacacg ggccggcgcg tgctggacgc ggcgcagcag tccttcgtgg
    17401 gcgggttcac cggcacgctg ctgatcgccg tgggtgtcgc ggcggtcggt gccctggccg
    17461 ccgcctttat tctgccccga gctcgtgttg ccgacgagga cggcacagcc cagtccgaag
    17521 ccgccgcccg cagcgacagc gccgacgccg ccgctacgtc ctgaagaccg gggagcggac
    17581 agtgcgtagg atcgactcca cagcccggcc cgcgggtgag agggaggtgg cgatggcccg
    17641 gccgtcgaag ctcagggtag cggtcagtga tcctgaccag tggctcagcg aacgcgagcg
    17701 ggcacagatg ctggcaccca aactgcgggc cttggcggac gagacgcgac tgacgctgat
    17761 cctgctcatc gcgcaacgtc cccgcaccgt caaggaactg caggaggcca ccggcttgag
    17821 ccagaccctg gtcagccatc acctggcccc gctgcgtgaa cagaacctcg tagaggcgat
    17881 tcccaagggc cgcagcaatc agtacgtgat gtgctgtcag acgctggccg agccgttgcg
    17941 catgttcgcc agccttgccg ccatggaccc tgagacggtt gcggcttgcc tccagacggg
    18001 ggccggacag ccggccgcgg cgcagggcgc ctgagcccgc cactcgccac tcgccactcg
    18061 ccacaggggc cgtgttccac gcagacgcgt ggaacacggc ccctgtggcg tgcccccctg
    18121 ctactgccgc agatcgttct ggaagcggtc ccggatgtcg agcgtgctga gggcattggt
    18181 cgcgcgaggc gggatcgcgc ccgtgcgagg cagcgtcttg atacagatca ggtgcgggcc
    18241 gggagcggcc tgggctcgca gcatcgcggc ccgcacgtcc tcctcccggt cacagacgac
    18301 cgcgtcggcg tatccggcgg ccttcgccat ctcggggaac gaggtcgtcg ccgaggtcgt
    18361 cgcctgcccg cccgtcgact cgtgcacccg gttgtcgagc acgacgtgga tcaggttggc
    18421 gggcgcctcg ctgccgatca tcgacagggc gcccaggtgc atcaggaggg ctccgtcccc
    18481 gtccaggacc accacggtcc gctccggttg ggtcagcgcc acgccgaggc cgatggagga
    18541 ggcgtggccc atggagccct gcatgtagaa ggtgctgggt gtgtcggcca cggcgaaggt
    18601 gtcacggccg gtgaagccgg tggtggcgac gacggctgcc tgcggagcgg cagaggtgac
    18661 gaggcggatg gcttccgcgg cgggcagtcc ctcggtgtgc ggggagttgg ccgccgcggc
    18721 cttgccgatg gcgccgcgtt caaccagcac gaacggcgcc cgctgctcgg cgaggtcctt
    18781 ttccgccttc tccaggaccg cggcgaactc ctcgaccccg tcctgcgcgt acaaggtgtg
    18841 gtgcggggtg tcgacgctgt cgagaagccc gtgagtcgcc ggccccatca cggcgtgctg
    18901 gggttcgtcc gttgcggggt cgggccagcc ccgcaggctg gcgaaggtca ggatcggcag
    18961 ctggtaggtc atcaccagcg aagtgagcgg attgatgagg ttgcccagac cggagttctg
    19021 cagcatcacg taggcgcgct gtccgcccag ggcggcgccg gcggccactg cgagcgcgct
    19081 gccctcgttc ggggcgggta cgtagcgacc gggctcggtg ctcaggtgcg cgatcggtcc
    19141 accgaagtgg gagcagggaa cgccgctggc gaaggtgaag ccgccgtcgg ccaggaggtc
    19201 gcagaattct tgtgcagtga tcatggacgg ggcagctccg tttcgggggt ggtggacggc
    19261 gtgatgggcg tctcctggcc cgctgcgggc gcgctgcggg cgcggcgtcg catcttgatg
    19321 ccctcgatga tgatgggaat gccggagatg agcacgatgc cgatgacgat gccttcgatg
    19381 ttgtcgcgga cgaaggcgac ttggcccagg tagtagccga cgagagtcag gctgaccgac
    19441 cacagcaccg caccgatcac gttgaacagg aagaacgtgc ggtacgtcat gcgtccgatg
    19501 ccggcggtga tggggatgaa ggtacggaag accgggatga agcgggccat caccagggcc
    19561 ttggggccgt gcttgagcat gaactgctgg gcccgttcgg cattttcctg cttgaagaag
    19621 cgggagttgg ggcggcggaa gagagctccg cccactttgc ggccgaaggc gtagccgaac
    19681 tggtcgccca ggacggcggc tgcggcgatg gcgagcatga ccagccacag gggctggtgg
    19741 aggaactggt cgttggccac tagcagtccc gccgtgaaca gtagcgaatc gccgggcagg
    19801 aagaagcaga cgatcaggcc ggattcggcg aagacggtgg ccatgatgcc cagcaggccg
    19861 aagccggaga tcagggcctc ggcgtcgagc aagggtgatg aggcgaggtt ttgcacgcgt
    19921 gccccccagg acggtggtgc gaatgagcgg acatgccgcc tgccggcccc gtcgcgggac
    19981 cggcaggcgg gcggggttga tcagccggcg gcccagtcgg gccgctggtc gatgcgtacg
    20041 acggcgcaag tgatggacac cccgccgccg tgggcgacga tcagtacgtg gtcgcccggg
    20101 ccgacctgcc cggtttccac caggtgcgtc agaccgacga tctggtcgtt gaccgtcatg
    20161 tggcccaggt tgcggccgaa gtcgagcagg ccctggtcgg gggagaggcc catggggtcg
    20221 aggatgacct tcaggtagct ctcctggccg gtgaacacgt ggcagaccct ggtgacgtcg
    20281 cccggttcca ggccggcttc ggccagggtg cgcagggcga tctccgtgcg cagctcgccc
    20341 tggcggcgca cgacctcggc gacggtctcc tccagcccgc cggcggcggc caggcgctcc
    20401 ttgaagtcca tgccgcggcc gaccgtcagc gacgggggga aaagcggttc cgtaccgcgg
    20461 tactgctcct cgacctcggc agtggagccg gtgttgatgg acaggaggct cgcgaagccc
    20521 tcggacttcg acagcaggat cgcactgccc ccgtcaccga gcaccccgtt ctggatgccg
    20581 aaggcccacc ggttgaagtt gggggttccg acgttgtcgg cgccggtgag cagagcggcg
    20641 ctgcgttcgg gtacggcctt gaggtagcag gcggccagct ccagtgagcc gatcagtccg
    20701 ctgcaggcct gccagacacg gaaggagggc acgtcgcggt cggtcaggtg acgcaggatg
    20761 tagtgctgcg gcgaccagcc ttcggggccc tgttcgtgtc cgcaggcgtg gatgtggaag
    20821 tcgatgtcgt gcgggtgcag cgcggagcgt tccatggcct gccgggcagc ggcgaccgcc
    20881 atgtccggag cgggcatgtc gtcggcgacg gcggcgccgg tccatccgta gaactcgtag
    20941 tcgtcggcgt cgtacagacc cagcgcgact gccttccggg cgtcgacgat ctcggggatg
    21001 tacgtgccga gtccggcgat gcgaatgtcg gtggtcttca tgaagtcggt cctcgtccct
    21061 cgctcggtca ggccgaggcg tctgcggagt tcagttcgtt ggccagggct tgggcgacgg
    21121 tggtgatggt gccgtccttg aggagttgca ccatggggag tttgacctgg tagcggcgtt
    21181 cgacgcggtt gcggagttcg acggccatga gggagtccat gccgagccgg ttcagcggtc
    21241 ggttgatgtt gacgcgttcg ggccgcagcc ccatcacgac cgcgacctcc tgcttgagga
    21301 agtcgaggag ctcgtccgtg ggaggcgcct gtgctgcttc gggggcctgc gaggccctgg
    21361 catcgggcag ggacggttca gcggccgccg gtgcccggct ttcgcgactg gcctcggcgg
    21421 atgtgatctc ggccaccgga ggcgtgctgc ccattgccgc cacaggtgtt gcggagtcgt
    21481 ccgccttggt gtcggactcc tcctcgaccg gctccagttc gttggcgagg gcttgggcga
    21541 cggtggtgat ggtgccgtcc ttgaggagtt gcaccatggg gagtttgacc tggtagcggc
    21601 gttcgacgcg gttgcggagt tcgacggcca tgagggagtc catgccgagc cggttcagcg
    21661 gtcggttgat gttgacgcgt tcgggccgca gccccatcac gaccgcgacc tcctgcttga
    21721 ggaagtcgag cagttcggtg ctgggcgcgg cttgtgcagg agcggtggcc tgcggtgcga
    21781 tccggtcagt agccgggggc tcggcgaccg ctgcggaggc ggccggagcc gcggctggcg
    21841 cggatgcgac ccgactggac gtgtcaggct cggtgacctg ggacgatggg cggggttcgg
    21901 tgttctgctg ctcaggaccg ggagtcgggt ccgccgactg atcacggttg gtgaggtgct
    21961 gcaccagagg agcagcagcg gcgctcgggt aggcgcgggc ccaagcccgc cagtccgccg
    22021 gcaacaccgc tgtgtggagc ctgccttcgg ccagaatcct gcccagcacc gacagaccgt
    22081 cgtccgggct gaacgaggtc atgccgtgag gcagcagcgt gcgctcttcc tcctgctcct
    22141 tgcgcgccac catcccgacg ctgtcccaga acccccagtt gacgacagtg ccggagaggc
    22201 cctgggcatg ccggtggtgc gccagcgcat cgaggaacgc attcccggcc gcgtacccgc
    22261 ccagcatggg ggagctgagg agtgcggagc cggaagagaa cagaacgaac gcctcaaccg
    22321 actcctcgcg cagcagccgg tgcagattcc aagccccaga gaccttcgcc gccaggactc
    22381 gatccatctc ggcgccactc atgtcactga gcagggtgta gtcgatgaca ccggccgcgt
    22441 ggaacacacc gcgcacaggt ggcatccccg cgcggcgtcg cgactccagc gtcgcctgca
    22501 tggcatgggc gtcggcgacg tccacagcct tatacgtcac gttcaccccg cgctcgcgca
    22561 attgccggag cacggcgacg gcggtggcct gcggatgagt ctcgcttact accgcgtcct
    22621 gctcgggcag cgcactgcgg ccggtgagca gtaggtggcg ggcgccctgg tcggccagcc
    22681 acagcgccag ttggccgccg atgccgcccg cacctccggt gaccaggtag gtaccgtcgg
    22741 catgaacggt gacagagcgg ccgcgtggac cgccggctgt gacggatgac tggccgaagg
    22801 acagcacgac cttgccggtg tgccgggcct gggcgatcaa ccggaaggcg tcggcggcct
    22861 tctcgaccgg gtacaccgtg tgcggcagtg cctcgagagc gccctcgtcg accagggtgg
    22921 cagcggcccg caggacacgt ccagcgcgtt caggcgcgtg ttggatcatg tgcacgacgt
    22981 cgatggcgtg gaaggaaagg ttgcgggcga aggcaccgag cggcaacggg ttgttgtcga
    23041 ggatgtcgcg tttgctgagt tccaggtagt gcccgtacgg ggccatcagg gacaggttcg
    23101 cctcgatggc gtcaccggcc agggtgttgc agatgacgtc gaagccctct gcgacagccg
    23161 gcttgaaggt gtcggcgaag gcaaggcttc gggagtcggc gacctgctcc acgccgagct
    23221 cggtcagcag ctgccgcttg gcgtcactgc cggcggtggc gaagacgcgg gctcccttcc
    23281 agcgggcgac gttcagtgcg gcccggccgg tgccgccggt cgcggtgtgg atgagtatct
    23341 tctggtcccg ttcgaggcgg gccatgtcgt gcagggcgtg gtaggcggtg aggtaggcgg
    23401 ccggcagggt cgcggcctcg gccgcggtca gcctggccgg cttgggtgcc gtgaggcagg
    23461 cgcgggtgac gacctcggag gccagggccc cttcggcgaa ggcgatgatc tggtcgccca
    23521 ccgcgacgtc ggtcacgccc gagccggtct cggtgaccgt gccggcgcac tcccagccca
    23581 tcaccggcgg cctgtcgtcc tgcccgggat acatgcccag gctcaggagc acgtcgcggt
    23641 agttgacccc ggcgtggctg acctggatac ggacttcgtc cgcggcgagg ccgcgcgagg
    23701 ggaccgcggt cagctgcagg tcgtcgatga cgccgggtgc aggcagtgac agcgcctgcg
    23761 gcggaggggt ggcggccgcc gcggggcgca gccgggctgc caggcgccgg ccgttgcgcc
    23821 acgcgacctg gttctcctgg tcggggtgga gcagttgctc cgccagggcc gggacactgg
    23881 ccggggaacg gtcgaggtcg accaggcgag ggttcagcgc cggtgcctcg gcagccagcg
    23941 tgcggcccag cccccacgac atggcctgga aggggtggcg tacccgttcc ccggttccgg
    24001 ttgcctgggc gagctgggtg accagccaca gtggggggtg gccgagtggt tccttctcca
    24061 gggccctggt caggtgcagg acgctgtgcg cggcgagcac ctgggtgcgg tggatctcgg
    24121 tgggtgtggc gtccaggccg gtctgggcgt ccagggccca cagatggatg atgccgcggc
    24181 aggcgccgta gcgggcgaca tcggtcagga cctcgcggta gtgctcttcc ttggtggggt
    24241 cgatgcggta gcggtcgccg cccccggcca gctggcccgc gccggcggtg acggcgacga
    24301 cgcgctggtc gcggccgttc agttcacgcg ccagggcgcg cccggtgggc ccgctgtcgg
    24361 tcaacagcaa ccagaagccg tcggggtcgg tggcgcccgt cgctggggcg ggaagggggg
    24421 cttcgtccca gctgagtgtg tgcagccagg tgtcgcggtc gtcgctggcc ggggcagccg
    24481 gggagccgga ggtgcgggat ggcgtcacgg gatcctcggt agggggggtg agcagggcgg
    24541 gggcgtggcc ggccaggtac tgcaggcgca gtccgcgcat ctgggcgatc agacggccgt
    24601 cgtcggcgcg gatgtcgatg tcggcggcga acgagtcctc gcgcggggat ggcagcagct
    24661 tggcgtggct gaacagggag gcgggcggct gctggtagaa gcggacttcg tcgatgccgc
    24721 cgaggacgaa gacgccttcg tcgccgggag cagtcagctc acgggcggcg gccatggcgt
    24781 gcccgctcgc gtccaggagg gccgggtgga agtggtggtg ggcgagtccg tcgaggagcg
    24841 cggctgggca ggtcagctgg gcgaggacct cgccgtcggc gcgccacagt tcggtgatgc
    24901 cttggaaggt gccgttccac tggtttccgc gggcggcgtt ccacgcgtag aagtcgtcgg
    24961 cgtcctggtg ttggggcagg cgggcacgaa tggactggag cgactcgccc gctcggggag
    25021 tgtcgccctc caccgcgcga gcagttgctt cggtgtgcag agcccagtcg tcgtcggcgg
    25081 attcccggct gaggatgcgg cagtgaagtg acgagtccgg acgcggagtg acagtgacct
    25141 ggacttctgg tgcgggcccg tcctcgtcga ggaagagggc ccggtgatag cgcacctcgc
    25201 tcaccgacag cgctccggat cccagttcgg tgcgtgcggc agcgctgacg agctccaggt
    25261 gggctgtccc cggcaggatg atggtgtcct gaatgcagtg gtcgcgcagg taggggtggt
    25321 cagcgagccg aagtggacct tgccaggtgc gggtcgcgtc ctcggtgggt gacggcttac
    25381 cgagcagcgg gtgcgtcgcc tgctccctac ccgatgcagg ctcggcaggt gccgcggggg
    25441 cggccgcggg acgggctgga ccgggactga tccagtggcg ggtgcgctgc cacggatacg
    25501 tgggcagggc cacgtagctc ccgtcggcgg tcagcttgtc gaggtcgaga cgggcaccgg
    25561 ctgtgtgcag ggcggccgcg gaggtgagca gggagccgcg ttcgtccgcg tgccggcgca
    25621 ggctgccgac cgcggtggtg tcggcgctgg tggccatgcg gctggtctcg cggattcctg
    25681 acacgagcag cggatgagga ctgacttcga cgaacacggt gtcgccgagg tcgagctggc
    25741 cctttaccgc gccgacgaag tcgaccggtt ggcggatgtt gcgcacccaa tactcggcgt
    25801 tcatgccgga gccgtcgatg acctcgttca gcagggtgga gtgcaggggg atggtgcctg
    25861 cccgcggtgt gaggtgggac agctcggaga gcagatcctc ctgaagagcg tccatctgcg
    25921 ggcagtgcga cgcgaagtcc acgttgaccc gtcgattgtc gacactgcgc gcatcgaggc
    25981 cggccagtac ctggtcgaga gcctcaccat caccagacag gagggtggaa gtggggctgt
    26041 tgatggcggc tacggccacc gtgtcctcgt gaccgaccag cgctgccgct gcctcgtcgg
    26101 cgggaagagc gacccaggcc atggtgccgc ggccggacag gcgcttggcc agtcggctgc
    26161 ggcggcagat caccgcggcg gcgtcagaga gcgagagagc gccggcgatg taggcggcgg
    26221 cggactcacc catgctgtgg ccgatgacca cgtccggttc gatgccccag gagcgccaga
    26281 gctgggcgag ggcgatctcg atggcccaga gggtgggctg gatgacgtcg agttccttga
    26341 gtcgctcttc atccgccgag cgcagcagct cgatgactga ccagccgttc tccgtcctga
    26401 tggcgtcgtc gcagtcccgc atggcctggt ggaagaccgg ctcgctgtcc aggagctcgc
    26461 ggcccatgcc tggccactgc gagccctgtc cggggaacac gaacgcgacc cgtggcgtcg
    26521 cctcggagtc ggtgtagtcg ctgaaggaca ggccgggctc gttgtcgccg tcggcgaacc
    26581 cccgcaacgc ggcggcggcc tcggcgtggc tctggacggg aagggcgagg cgggcgtcgt
    26641 gaggggtacg gcgcagcgcc gcggaatggg cgatgtcccg cagcttctgg cgcgcgccgg
    26701 ggccctcaag gtggtcggcc atgctgcggg ctgcttcgga cagggcttcg gggctgagcg
    26761 cggacaacac cagcagctcg ctgcgcgcgt ccggagctgt gtcccgggcg gtggtgcgcg
    26821 gctcgggggc ggcttcgagg acgaggtggg cgttggttcc ggagaagccg aagctggaga
    26881 ccccggcgat ggccggccgg tcccgctgcg gcagaggggt ggcgtgggtg ggtacggcga
    26941 gtggcaggtt ggcccagtcg acggtggggt tggggttctt caggtgcagg ttgggcggga
    27001 tcgtcttgtt ctccaggcac agcacggcct tgatgagacc ggcgattccg gcggctgcct
    27061 cggcgtggcc gatgttggtc ttcactgagc cgaccaggca gcgatcgtcc gaggctcggg
    27121 cgccgacgat gtcggccagg gcctgcagtt cgaccgggtc gccgacgctg gtgccggtgc
    27181 cgtgggcctc gatgtagtcg atgtcggcgg ggtccacggc ggcgtttgcg taggcgcggc
    27241 gcagcacgtc acgctggcct tcgacggcgg gcgtgaccag gtagccactg ctctggccgt
    27301 cgttgccgac ggcggatccg cggatgaccg cccggatgcg gtcgccgtcg gcgagagcgg
    27361 ccgacagcgg cttgaggatg acggctccaa tgccgtcgct gcggacgaag ccgtcgcccg
    27421 aggcgtcggc gaacttgcag cggccgtcgg aggcgagcat gccggcgccc gagtagacga
    27481 cgccctcttc cggcaggagt acgagattga ccccgccggc gatcgccagg gggcactcac
    27541 cgagccggat cgcctggacg gcgttgtgga cggccacgag cgcggaggag caggcggtgt
    27601 cgacggtgaa gctgggcccc cgcaggtcga atgcgtagga cagacggccg gaggtgatgg
    27661 cgcgggcggc cgcaccggtc atggcgtaca agtcgagttg atcgcggtcg tcgtactgca
    27721 gatgccagta gtccccgccg agctggccaa tgaagacgcc cgtgtcggtg ccggcgatgc
    27781 ggggcagggg ctgacccgcg tcttcgaggg cttcgtaggc gacctccagg aggagccgct
    27841 gctgggggtc catgcgatcg gcctcccggg gggagatacc gaagaattcc gcgtcgaatg
    27901 cgtcgatgtc gtggagcaag ccgccccacc ggctcaccgt gcggccgggc gtgcggggcg
    27961 tggggtcgta gacggcgtcg acgtcgtagc ggtccggcgg gatgtccgtg atggcgtcgc
    28021 ggccctggag cagcatgtcc cagagttgtt caaggctggt ggcgtcggcg aaccgtccgg
    28081 ccatgccgat gatggcgatc ggttcactgg cagtcccagc cgcgcgggtg gagtcgtgag
    28141 gcatgaatgt ccttccgggc atgacgaagc cgttcactgg tgaagcagca cggaaggaac
    28201 tgcggtgcgg gcgcggcaga ccggcagctg ggccggtccg gtggcgggcg atcgcaccga
    28261 ggacagaacg agagtgaggc gggaaggagc cggtccgtcg actgagcgat cacgtgcggg
    28321 gcgagcgcac tgaccgttca cgggccgggc gcggctatcg gcacagccgc tgcttcccga
    28381 tgtcgctgtg gcactgggcg ggtgccctgg tgccactacc cccgctgttt cgacatgtat
    28441 cgagattgac ccgacgcggg tcgcccgcgc aacgcggcgc gaggtgacgc tcgtcacact
    28501 gcgacaggct gtggcatgag gttgacattc atcgaagcag gagtgaaggt ggaactctga
    28561 ttcgttgttt atctatatag gcggttgtga tgcgctcgct cgcgtcgccc tccgagccgc
    28621 cgcgacagga gccgattccg atgagtgatt ccgtcggcct cgacgctgag caggccggct
    28681 cttgctgtgc cgcgatcgct gaatttcggc ggcgggctgc ggagcgcagc gaacaacaca
    28741 agcaggcgga caccgcagag gatcccgcgg cttcctcgtc cgatcccacg cgagatgcct
    28801 gactgccgcc cttcccttcg tgaaaggaca ccgcacagtg gttgacctcg gctccgaccg
    28861 cctcccagtc gccgtgatcg gcgccggccc cgtcgggctg gctgccgccg cgcacctggc
    28921 cgaacgcagc gtccccttcg tcgtcctgga agccggagac gctgcggcga cagccgtgca
    28981 ggcgtggtcc cacatccagc tcttcagccc atgggagttc aacaccgatc ccgctgcccg
    29041 ccgactgctc gcggccgccg gctgggagga gcccgacgcg tccgccctgc ccacgggcgg
    29101 ggatctcgtc aagcagtacc ttcagccgct ggccgaactt cccgcgctgg cctcccacat
    29161 ccgatacggc gccgaggtca ccgccatcag caggctgggc atcgaccgtc tgcgcaccgc
    29221 cgaccgggac gcggcgccgt tcgtcctgcg cctggccgac ggtgaggagg tgctggcgcg
    29281 cgccgtcatc gacgcctcgg gcacctggcg tcagccgaac cacgtcggtg cgaacggcct
    29341 gcccgcccac ggcgagaagg acgccgccgc ctggatcaac cacggccttc ccgacgtctt
    29401 cggagcggac cgcgaccagc acgccggccg tcacaccgtc gtggtcggcg ccggccactc
    29461 ggcagccaac actctgctgg ccctggcgga gctggccgac accgcaccgg gcaccaccat
    29521 cacctgggcc atcaggggcg ccgaccccgc cgcctccttc ggcggtggca gtgacgacga
    29581 gctgcccgca cgaggcgcca tcggctccgg tctgaagatg ctcgtggaaa ccggccgcgt
    29641 gactcttgcc gccaacttcc gcacccacgc cgtccgccgc ctgggcgacg acccctcgcg
    29701 cgaccaggtg gagctcgtct cccgggccct ggacggcacc gagcgaagcg ttaccgccga
    29761 ccgggtcgtc gcggccaccg gcttcaggcc cgactaccgc atcgtcgacg agctgcgcct
    29821 ggagctcgac ccgatcatgt ccgcgccccg tgcgctcgcc ccgctcatcg accccaacca
    29881 gcactcctgc ggcaccgtca ccccgcacgg ctaccgcgag ctggcccacc ccgaacccgg
    29941 ctactacgcc gtgggcatga agagctacgg ccgcgctccg accttcctca tgctcaccgg
    30001 ttacgagcag gttcgctcca tcgccgccgc gctggccggt gacttggaag cagctcagtc
    30061 ggtcgagctg cagctgcccg agaccggagt gtgctcggtg actgccgggg gagaggccct
    30121 cgccctgcgt ctcgggttga ccaaggatca gcacgagcag cttctccatg tcaccgcgaa
    30181 gcacctgggc acttcggcca cggcttcgga cgccgtgctg tccgccgcga cggagctcgg
    30241 catcgaccag accgcggccc tgcagctggc cgcctacgcc gccgacatgt tcgacgcgcc
    30301 cggcgccccc ggctgctgaa ccgccccgac cggtcgtccc tccccgccct ggggaaggac
    30361 gaccggtcag cagtctggtc aggtgatgcg gtgcaccttg tgctgcgccg cctgtgctct
    30421 ggggcggacc acaaggaggt cgatattcac gtgaggcggc cgggtcaccg cccacgtcac
    30481 cacgtcggcg acatcatcgg cgaccagcgg gtccggaaca cccgcgtaga cggcatccgc
    30541 cctgttcagg tcaccacggt agcgattcag ggagaactcc tcggtgtgga ccatcccagg
    30601 agcgatctcg accacccgca aggcctcccc gcacacctcc agacgtagag tctcggccag
    30661 tacgtgggcg ccgtgcttgg cggcgctgta accgccccct ccttcgtagc aggtgaacga
    30721 cgcggtggac gagatcacga ccaccacccc gtcaccagac gccttcagag ccggcagcag
    30781 ggcctgggtc atgtgcaggg cgccgatgac attcacctcg tacatcgacc gccagtcacc
    30841 aggatcggcg ttctcgatgt gctccgttcc gtaggcccca cccgcgttgt tgaccagcac
    30901 gtcacacgcc ggaaactggg cggcgaaggc gaggacggcc tcccggtcgg tcacgtccag
    30961 ggggaacacc tggaccattc ctccgtcgtt tctgatctcc ttggcgacgg cctccaggcg
    31021 gtcggcccgg cgggctgtca ggacgacctc gaacccctcg cgagccagcg cccgcgccgt
    31081 tgccgccccg atgccgctac tggctccggt gacgaccgcc gtcctcgtgc gagctgcctg
    31141 tgtatcggcg gtacgcatgc ttgtcgtgcc cccagtgctg attagacgct catcgaatca
    31201 atcgatcttg gcaggagacg aaacgagtgt caacatagat gcatgtcgaa gctagcgcag
    31261 ttggcggcca ccgcctccgc tccaccgtgc tgcccgtccc tcacggaccg ggagctcacc
    31321 gacgaggagg ccgaggtcac cgccgccatg ttcaaggcgc tgggtgatcc ggtgaggctg
    31381 cggctgttct ccaaggttgc ttcccatcct gagggggagg cctgtgtgtg cgacatcgcc
    31441 gacgtcggcg tctcccagcc cacggtcagc caccacctga agaagctccg cgaggccggc
    31501 ctgctgttgt ccgagcggcg cggcacctgg gtctactacc gactcgcccc gtcggtgctc
    31561 gctgccctgt ccggattgct taccacccgc gactgatccg cttcacggag tatccatcgg
    31621 acctagtctg cgcggctgac atctgccacg ccacgtgatc tctgcgcgct gtgcatgccc
    31681 cggcccgtag tgacgcccca cgcggccagc ggtccgtcga gggtggtggc tcactcgtcg
    31741 tgctgcctgc tcccgtgtct gccccggctg cgcttcgggg catctcggtg tgccttgatc
    31801 tcctgagggc accgccagta gtccccaagg actcgctgca cttgggttcc ggcaagtggt
    31861 tgacacccgc catagatcga cgccaagcta attcctgatt cggcaaaagt cgatatagcc
    31921 aagtcacggc cggctctatg tggcgccctc gtagccgcaa ctttcccttg cgcactgatg
    31981 cgctcgggac ctccgcaccc tccaattcgg cagtgctacc cgccgggctg cccccccgcc
    32041 ggttcggctg gctgtccaca gtgcccttgc atgagaggac tcgcacatga ccagcaccat
    32101 cctcaccact gctcaggccc actcccacaa cattctgcga agcgacggcg accgtgctgc
    32161 ggagcccaac atcttcctgg cgggcgggaa agacattccc gaggaccagc ggatgcacga
    32221 ggtggaaccg ctcacggacc gggtcaaact caacgtcgag aaccgctacg agcacttcga
    32281 ggcgacgtca gaagtgcgag aggtcgacgg gcgctccctg cgtgtctacg gctggatcta
    32341 tcggacgtac gtagccgagt agcaggccag tcacgtgaag ggcggggcga atgtcttcca
    32401 ggaaggatcc cctcagaatg gcgcgcgagt cggccagtgc tcggaccagc gagtcggggc
    32461 tgcccatcga accggtctac gggcccgacg ccctggcgga ctgggacgcg gccgagaagc
    32521 tgggcgagcc cgggaagtac cccttcaccc ggggcgtcta cccgtcgatg tacaccggcc
    32581 ggccgtggac gatgcgccag tacgccggtt tcggcacggc cacggagtcc aacgcccgct
    32641 acaagcagct gatcgccaac ggcaccatgg gcctgtcggt cgccttcgac ctgcccaccc
    32701 agatgggcca cgactccgac gcgccgatcg cgagcggcga ggtcggcaag gtcggcgtcg
    32761 ccatcgactc catcgacgac atgcgggtgc tgttcggcgg gatcccgctg gacaaggtct
    32821 ccacgtcgat gacgatcaac gcccctgcct cgctgctgct cctgctctac caactcgtcg
    32881 ccgaggagca gggcgtgagc gccgacaagc tcaccggcac gatccagaac gacgtgctga
    32941 aggagtacat cgcgcgcggg acgtacatct tcccgccgaa gccgtcgctg cgcctgatcg
    33001 cggacatctt caagtactgc cgggccgaga tcccgaagtg gaacaccatc tcgatctccg
    33061 gctaccacat ggccgaggcg ggcgcgtctc ccgcgcagga gatcgcgttc accctcgcgg
    33121 acggcatcga gtacgtgcgc accgcggtcg cggccggcat ggacgtggac gacttcgcgc
    33181 cccgcctgtc cttcttcttc gtggcccgca cgacgatcct ggaggaggtc gccaagttcc
    33241 gcgcggcccg ccggatctgg gcccgggtga tgaaggagga gttcggcgcg aagaacccca
    33301 agtcgctgat gctgcgcttc cacacccaga cggcgggcgt gcagctgacc gcccagcagc
    33361 ccgaggtgaa cctggtccgc gtcgccgtgc agggtctcgg cgcggtcctc ggcggcacgc
    33421 agtcgctgca caccaactcc ttcgacgagg ccatcgcgct gcccaccgac aagtccgcgc
    33481 gcctggccct gcgcacccag caggtgctcg cctacgagac ggacgtgacg gcgaccgtcg
    33541 accccttcgc cggctcctac gtcgtcgagc ggatgaccga cgacgtcgag gcggcggcgc
    33601 tggagctgat gggcaaggtg gaggacctcg gcggcgcggt caacgccatc gagcacggct
    33661 tccagaagaa cgagatcgag cgctccgcct accgcatcgc ccaggagacc gactccggcg
    33721 agcgggtcgt ggtcggcgtc aaccgcttcc agctcgacga ggaggagccc tacgagccgc
    33781 tgcgcgtcga cccggccatc gaggcccagc aggccgagcg gctggccaag ctccgcgccg
    33841 agcgcgacca gcaggcggtg gactcggcac tggcggccct gaggaaggcc gccgagggcg
    33901 aggacaacgt cctgtacccg atgaaggacg cgctgcgggc ccgggcgacg gtgggcgagg
    33961 tgtgcaacgc gctgcgggag gtctggggga cgtacgtgcc ctccgatctc taagacgagt
    34021 ggtccaattt gccttgctga gtgaggagtt catttcatgc ggcagctacc gatgcgagtg
    34081 gttgtggcca aacctggcct cgacggtcac gatcgtggag cgaaggtcgt cgcacgagct
    34141 ttgcgtgatg ccggagtgga agtcatctac acgggtctgc accagacgcc ggcgcagatc
    34201 gtcgccacag caatccagga agacgctgac ggcatcggac tatctgtgct gtccggagcg
    34261 cacatgaccg cgttcacgga ggttatgaag ctgatccagc tggaggaggc gacgaacatt
    34321 atcgtcttcg gcggaggcat cattcccgat gacgatgctg cgaacctcct cgaaggggga
    34381 gtcgcggccc tatttacacc ggggacgtcg atggcgacgg tggtcgattg ggtgacgaat
    34441 catgtgggtg gacggcgaac cggccgggtc ttggcgcagc ctgttcccca tagcgcgcag
    34501 gctgctcctg ctgggccctt ccaacgaagc cgttgaagca tcccagatcc gggagttcag
    34561 ccacatacga cggcggggtg tcttgcttga ctcggccgcc cctgcgttgc gtaaaacaca
    34621 gtgcgctcag cgccttgagt caccggagac gcttcggcga aaggggaagt gaccgaagta
    34681 gcctgcgccc aactccagct gaccgcgcgt ctgaccgcgt gtcttgccag ggaagacgtt
    34741 gcacaggaca aggttgaagg gggcacctcc cgactcctcg atcgctgtga ccttgctgcc
    34801 ggatgcaatg gcctatgggg ctcctcacac ggagtggaac ggtttggcgt caggcgacgg
    34861 cgacgacctc ggccgacacg gacgtgtcgg accgggccgc gagataccgc tcggcgtcca
    34921 gcgctgcggc gcagccggag ctggccgcgg taatggcctg gcgataggtg tggtcgacga
    34981 cgtcaccggc gccgaagacg cccgggacgt tcgtgcgtgt cgaaggagac tcgaccatca
    35041 agtaaccctc ggagtcgaga tgcaactgcc ccttgaagag ctcggtgcgc ggatcatggc
    35101 cgatggcgat gaacaggccg gtcgtggcca gttcgcgagt ctcgccggtc agggtgtcac
    35161 gcagcgtcat gccggacagc atgccgttct cctcgtggag tgtggcgact tcgctgtcga
    35221 aggcaagaga gatcttgtcc tcggagaagg cgcggttctg catgacctgg gaggcgcgca
    35281 gagcggaacg ccggtgtacg acggtgaccg agcgggcgaa gcgggtgagg aaggtggcct
    35341 cctccatggc agtgtcgccg ccgccgacga ccacgatgtc gcggtcccgg aagaagaagc
    35401 cgtcgcaggt cgcacaccag gacacgcccc gcccggacag ctcgtcctcc ttgggcacgc
    35461 cgagcttgcg gtaaccggag cccgtggcaa cgatcaccgt cctcgcacgg tggacggtac
    35521 cggcggtgtc ggtgacggtc ttgacgtcac cggtcagatc gaccgcgacg atgtcgtcgt
    35581 cgaccatctc ggcgccgaac ctctccgcct gggcccgcat gttctccatg agctcggggc
    35641 cctggacccc gtcggggaag ccggggaagt tctcgacctc agtcgtggtc gtgagcgaac
    35701 cgccgacgaa tatggcgccg ccgaagacga gggggttcag gctggcgcgg gcggtgtata
    35761 gcgcggcggt gtatccggcc gggcccgagc cgatgacgat gacgtcgcgc acgtccttgg
    35821 cggtgctcat gactgaggct ccggggcgat ctccttgatc agtccctcga ccagcaccct
    35881 gatctcatcg cggatggggc ggacggcctc gacgccctgg ccagcggggt cgtccagttg
    35941 ccagtccagg taccgcttgc cggggaaaac cgggcaggtg tcgccgcagc ccatggtgat
    36001 gcagacgtca gactccttga ctgcgtccgc ggtcagcaac ttgggcacct cggcggagat
    36061 gtcgatgccg acctcggcca tggcctcgac ggcggccggg ttgacgttct ccccgggggt
    36121 ggagccggcg gaccggacct cgacgcggcc cccggccagg tgggtcagcc acgcggcggc
    36181 catctgcgag cggccggcgt tatggacaca gacgaacagc acggacggct tgtcggacat
    36241 caggaggtct ctcttgtctc gcgaccatat caggtgcaaa tgacatcagc acccggtggt
    36301 gtcagtcacc actgatgtga gagtatcagt gcatgatgac gtcagtcgac actgacctga
    36361 ttcgggttct agcggatccg ctcaggctgc agatcgtgac cctgctcgcc aacgagacgc
    36421 tgtgcaccac ccacctcgtg gaggagaccg gtgcccggca gaccaacctc tccaaccacc
    36481 tgagagtgct gcgcgaggca ggtgtcgtcg agacggagcc gtgcggccgc tacacgtact
    36541 acaagctccg cccggacgtc atcgcctcgc tcgccggtca gttcgccgac ctggccgagt
    36601 ccgcccgcaa cgccgccgac aacaagaggg cctgtccgtg acccgcaccg aagcacccgc
    36661 gatcaccgag gagccctccg tcgtcgcgaa gctgtcgacg ctcgaccgct tccttgccgt
    36721 ctggatcctc atcgccatgg ccgtcggcct cggcctgggc cgcgccatcc cgggcctgaa
    36781 cgacgccctt gccgaggtcg agatcggcgg catctccctg ccgatcgcca tcggcctgct
    36841 gatcatgatg tatccggtgc tggccaaggt ccgttacgac aagctcgacg ccgtcacggg
    36901 cgaccgcagg ctcatggcct cgtcgctggt gatcaactgg atcgtcggcc cggcggtgat
    36961 gttcgcgctc gcctggatct tcctgccgga cctgcccgag taccgcaccg gcctgatcat
    37021 cgtcggcctc gcccgctgca tcgccatggt catcatctgg aacgacctcg cctgtggcga
    37081 ccgcgaggcc gccgccgtac tcgtcgccct caactccgtt ttccaggttc tggcgttcgg
    37141 cctgcttggc tggttctacc tcgacctgct acccggctgg ctgggtctgg gcgacggcga
    37201 acacctggac atctccatgt ggaagatcgc cctcaacgtc gtcatcttcc tgggcgtccc
    37261 gctgctcgcg ggcttcctca cccggcgcat cggcgagaag aaactcggcc gagagaagta
    37321 cgagtccaac ttcctgccga agatcggtcc gtgggcgctc tacggcctgc tgttcacgat
    37381 cgtcatcctc ttcgccctgc agggcaagac catcacttcg cagccgctcg acgtcgcccg
    37441 catcgcgctt cccctgctgg tgtacttcgc cgtgatgtgg gcggggacct tcctgctggg
    37501 caagacgatc ggtctcgcct acgaccggac ggccaccctc gccttcaccg ccgccggcaa
    37561 caacttcgaa ctggccatcg ccgtcgccat cgccaccttc ggcgtcacct ccggccaggc
    37621 cctgtccggc gtggtgggac cgctcatcga ggtgcccgtc ctgatcggcc tcgtctatgt
    37681 ctcgctggcc tggcgcaaga agttcacccc gtccgctccg gtcactgagg gcaggggcta
    37741 ctgatgcatt gcctcatatc ccgcaccgtc cggtccacca cgtgcgcggc ggcgcaggcg
    37801 gcatgacaca gcacaccgac gtggtggtga taggcggcgg ccaggcagga ctcgccgccg
    37861 gctaccacct gcgtcgccag ggccttgact tcgtcgtcct cgacgcccag gccgccccgg
    37921 gcggagcctg gcagcacacc tgggactccc tgcacctgtt ctccccggcc gccttctcct
    37981 cccttcccgg acggctcatg ccgccgcagc caggcaagga gtacccggat gccgggcacg
    38041 tggtggccta cctgaacgac tacgagaagc gatacgacct tcccgtacag cgagcggtcc
    38101 gggtgatcgg cgtgcacgac gacggccggt tgctgcgagt ggagaccgac tcgggcacgt
    38161 ggcgcgcacg cgcggtgatc agcgcgaccg gcatgtggtg gcgtcccttc ctccccgccg
    38221 tccccggtcg agaggacttc gaggggcgtc aactgcacac cgtctcctac cgcagaccgc
    38281 aggacttcgc cggccaacgc gtgatcgtcg tcggaggcgg caactccggc gcacagatcg
    38341 ccgccgacct cgctcacgac accgaactga cttgggtgac ccagcgtcca ccccggtacc
    38401 tcgccgacga catcgacggc cgcgccctgt tcgacgcggc caccgcccga cgccgcgccc
    38461 tcgacgacgg ccgcaccgac accggcggcg tcgcctcgct gggagacatc gtcgccgtac
    38521 cgcccgtgcg cgaggcccgg gacgccgggc ggctcaaggc gtcacccatg ttcgcccgcc
    38581 tcgtccgtga cggcgtcgtc tgggacgacg gcacgcgggc gcccgccgac gcggtcatct
    38641 ggtgcaccgg tttccggccc gccctctcgc acctgtcgcc ccttggcctg cgcggctcgc
    38701 gcggccacat cgacacggta ggcacgcgcg ccgcggcgga cccacggctg cacctcctcg
    38761 gatatggaga ctggacgggc cccgcctccg ccacgctcat cggcgtcgga cggccggccc
    38821 gcgacgcggc ccgcgagatc gccgaattcc ttggcgggga agggtaagcc gtggacggtg
    38881 accagcaggg cggtccggat ggaggcgcag cgtcgactca ccgagggatt ttgaggtcca
    38941 ggggcctcgc gatcacccga cgtgcgctca ggcgtggctg tggagtagtg agccaactcg
    39001 tcactgaggc tgtggcaggg ttctactgca gacgtcgagg tcagttgctg gaggcgtcgt
    39061 cacgttggcc tgagccgcgg cgccgcctcg gtgttcggcc ggggatcggg atgtggctcg
    39121 gtcggctgac gatgatcaca tcggttatgc cggagagcct caggagcgcg ttgcgggtgg
    39181 tgtcgtgctc ctggccggag caggactcgt cgtagatgaa gacggtcatg tggcgatacg
    39241 cggtgttgtc ggagaggtag ccgatgtagt cctcgaagat ctccttctcg aaggacttga
    39301 agtcggcggc cttgcgtgcg tatttgacct cgatcaacag ttccagtgaa gggatcccga
    39361 aatctgctcg gtaggtgctg tggccgatcc ggcggagggt ttcttcgtcg acgaggtcgt
    39421 cgaacacagg ccggagcatg agccagagaa tgttctgaat ctcgcgctca gaggtaatgg
    39481 gccacttgat gggattctca aggtcatctc tgtcgtggcg ccattggcgc atcgcagttt
    39541 cgaatcgacg taggaggacc gagacatgat cgcggctgag aagcatgtcg tcgacgctgg
    39601 cggtgacaat gcgtgtgact gcgtcgagga gcagtgccgc ccgaggcgct ggcagctggc
    39661 cggtgtcggt caggatgatt ccgctgagca gtcgggatcg tagctgccgt agctcgtcgt
    39721 ggtccgttcg cagagggctc ttcgccgtgg ctgtcagcca gtgaaagcaa gcagcgtcca
    39781 ccaggtcatg gacggctcgg gggtccaccc tcaagtcagg cgcaatgccg acgatttgcc
    39841 gagcatgttc atggaacagg ccaagcaggg tgttggcggc acgcaacctt ggatcttgga
    39901 gcacctccac cagccagtcg tgggcccgcg gaacgtcgtc gcgggccgcg tcgacagcca
    39961 gggcgagacc gatgacttgc cgggcatcgt tgacgaaagc gactccatcg ggtgggaaag
    40021 gatttctccg ggtgagggca ggcaggccgg cggccagatg ttcacgggcg gtccgggaag
    40081 cggtcgaggg aaacgaggcg aggccgtagc cgaggccggc gagaccatgg ggatgagcaa
    40141 agcggtcctt gttgtccgcg agccacgtcg gcgtcatggg attgacttcc cagtcgaagc
    40201 tcaagcggcg tccgcccagg acgtagtggg cgagtagacc gtcaaggttg ccgggtgagt
    40261 tcgcccgccg gatgagctct tctagatagg aggtctgggc ggtcaggagc tgccccgtag
    40321 gatcggttgc gccgggttct tccaacgagg tcacaggaac cacctgctgg aacgcagctt
    40381 ggtggtgacg gcgtcggcgt tccagttccg tacgtggcgc aggtgcccga gcagctcggc
    40441 gatcagatcc gagtacgaaa ttgtcaccgg gttgcgcgat gggtacatgt ttcgccagga
    40501 catcgaagtg aaccggaatg cctgccgccc caaatactcg atgtcggtga aggtcgactg
    40561 agggtggagt ttcagcagga gcggtttggg aacaccgtgc agcgcacttt tgagatccat
    40621 ggggccgccc acggccacga gcagctcacg tttccccatg ggcactgcgt ggccgcgctc
    40681 cgggacgtag tgacccttgg ttctgctgtc ggccccccag ccccggatcc ccgcgctggt
    40741 gcggtcgaac atcacccagt cgtggtcggt actcacgtgc acgaacgcga actcgacttt
    40801 ggcatacgtc tgagtgagac cttcgaccaa cttcttgacc gcggtggcct cgacgtcctt
    40861 gaggggcttg aagacgtgga aaacaaggcg cagttcgtca cccgcctgcc aggcgttgcg
    40921 gttcttgatc gtgtcgatgc agtccctcag ggacagcaaa agttcgcgtg ggtagtcgtc
    40981 gtagtcggcc tcgcgagacg tgttccaaag caggtagttg ccgtccgcgc tgaatacggt
    41041 ggtgatgccc accacccgtt cgggctccgt gagtcggctc tccttgacgt gcgcgctccc
    41101 gatcccgatg accaactcgt gtgcaagggt gcgcggggcg gcgataacga aaggaattcc
    41161 gccgagtttg gcgtagcagg ccagcgcgat gctgttgagc gggtaggcga gcttgctctg
    41221 ccgcaccgtt tcaatccgca cctcctgtac gggtaccccc tgtcccatga aggctgattt
    41281 cgccacaaga tacggactgc tgtcgcctgt gagatgggcc tgggcttcgc tggtgatgac
    41341 gatggccaga tcgatatctc cgctgctcaa cgcagcccgg cacgcctcac ggtaggcccc
    41401 ggcatcagtc gctgtgccgt cgaaagcgtg catggcgata tcgcatccgg agagatggta
    41461 cttgcggatg aacccgagac cgaaaaccct cgcaccctgg attccgtaga gaaatttggt
    41521 gaggaagttc tcgacgacgc ccttgtgcgc acgaggcgtg acgacggcga tccggggtct
    41581 cttcctggcg aagaactcca cgtcgaaggg tccgaattca tccagaccgc ggtcggcgga
    41641 ccggcttgtc ttgtcgccag cctggtcgaa ctggaacgtc ggggactcgt aacgggtccc
    41701 agtcaccttc cggccgttgc tcgaaccgac cggtgggtcg atggtcacgg acaggtcgtc
    41761 agcgaccggg agggcgccgt tccgccccag gcgcgtaccg atgcggaccg ctccctcgta
    41821 gcgcccgaag gccccgagca gatcgaaagt cgcctgctcc aactcccgga ggatctgtcc
    41881 gctgtctgct ccggccaagg tggagagcac gtcgttgaac gtctctcgcc ggctctccaa
    41941 ccacgcgtga ccagcggcta cacgtgtgat tcctggggcg tcacgcagaa cgaggtcggt
    42001 gccgtcgatg tggtcgatgg caccgactgc acgcctggca gcgtgacgat ccatcgtagg
    42061 gtcggcttct actgtcacgt cctcgctcaa tacgtagagc ccgcgcacat cgacgccgtg
    42121 gtggatcagt tcctccaccg tcatgtcgat ctcgtagcgg ctcttcaccc cgacgattac
    42181 tccagggtgg ttcgatgggc cgatggctct gctgtcgaga cggaactccg ggtagacgtg
    42241 gagtttgccg agggctccct gtcgccgtcc gcgcaccgag ggctccagca ggtccttccc
    42301 gggcagtcga gagacaaaga ccggtggcac gcgtcgacgc agcttgtacc cccagcccag
    42361 caccgaccgg agcaaagcct cctgcacgag acgcatggcg agcgactggt gatcgcgtgt
    42421 ccggaaggca ccgctcagct gacagcagtg tcgcaccggg cactgacaac ccgggtagag
    42481 cgcacgctgc aagcggctgc ggaagacgag tgaggatacg ggcctctccc ggagaggagc
    42541 cggcgcctcg cttcggagta tgagttggaa cgaaaaattc cgtaccgagc actgggcatg
    42601 tgagacgaga ccagcaacgg ctcgcggaat gggagatttc ccggcgcgtg cctgcgattg
    42661 gtgtcgttgt gatctgctga tccagctaca ttgcggtacg agttgccgga ttctccgccg
    42721 accaacacgg tcagggccct tgacagcgat gcgtccaggg tcggccgcga gagcggcgat
    42781 ggtcagagaa ggcaccggcg ggctgccacc agaggaacca atagagcaga cgcttagaag
    42841 gcacgtgctc taaccactga gctacggggc tgacctgcgt aaacgcagct tccgggcgat
    42901 gtcccccagg tcgcggggga cacatggagg aatcgcggat tcccggtgac cgggggacgc
    42961 gagcgtcctc ggtcgggccg cacaaggagt ctcacactat cttcacgccc ccgaagcctc
    43021 tcgcggaaac aatcccgtac ctcatccgcg ttggtgatct ccgagctgag gagaggaagg
    43081 tgtcgggcct gaagctgttc cgcacggata cgacgactcg cggcatgact gaggtcattg
    43141 cgcgtcttgc cgggatcgag gccgaggtgc aggatctcgt cgagatacac atggagacgc
    43201 tgctcggcgt ccggttcctg gcaagcgagt acagcaccgg cccggtgcac ggaggccgga
    43261 tcgactcgct cgggctggac gagaacggct cgccggtcat catcgagtac aagcgcggca
    43321 cggatgccgg cgtgatcaat cagggcctgt tctacctggc ctggctgatg gaccaccggg
    43381 cggagttcga gcacctggtc cacgtccggc tcggggcgac ggccgcgtcc caggttctgt
    43441 ggagcggacc gcgcctgatc tgcatcgccg gcgacttcac ccgctacgac gtgcatgctg
    43501 tgcgcgagca ccggcgctcg atcgacctgg tccgctaccg aatcttcggc agcgacctgc
    43561 tcggacttga gaccgtggcc tccgtgagcg gcgccatgca ggtggcccgc cgggtacgac
    43621 gccaggctgt tgccggggcc gcggccggcg cccagggcgc ggcgatgcgc gagttggcgg
    43681 gcgcggtcga cgagttcctg ctcgggctcg gggacggcgt gaaccgggtg gagcgcaaga
    43741 cctatcgggc gtatcagcgg ctgcggaact tcgcctgcct gtgcccgccg cagcgcagca
    43801 agctgctggt ctacctgaag gtcgacccga aggatgtcga ccttgttccg ggcttcaccc
    43861 gggacgtgtc tggtctcggt caccacggga cgggtgatct ggaggtgcag ctgcgtacgc
    43921 cgagggacgt ggagcgggcg caggacctgt tcagggcaag ctacgcggcg gcgtgatcgc
    43981 ccgccgctgg cctcgtggcg ggctgcgcta cgtgtcgtgt ctgcggtcgt gggaggagcc
    44041 tctcgacgcg cgggcagggc gtggcggtgg actacctatg gtgcgcggga tcgccggttt
    44101 gtccaaccgg cgatcccgcg ctaccttgcc ccgctcgtgc ggcgggcgat gatcagcgtg
    44161 aacggctggc ggggcggtcg gacgtgaccg ccggaatcgc cggtgcactg gctgcgaggc
    44221 gggtcctgtg ctcgcggccc ggccgaggct ggcgcgtgcc cgtctcgtgg gcgagagatt
    44281 cggagaggtc ggccagcagc gagctcgggg tgtgcgagga cgcggtgatg gcccaggtgg
    44341 gccggtccgg gccggggccg gcccagatgg tccaggtggc tgggttctgg ggggcctgcg
    44401 cggtcagtgg gtcaaaccga acgcttgcct gcccgtcggg ggacgtccat cggatcccgt
    44461 gccctgtcag ggtgtgcttc cacccggcct cagtgagcgg ctgcgtggct gtggtgaccg
    44521 tcttctcgcc caccgggacg ccgatgaccg tgtcccagcc gtcgccgtcg gcgaggtggt
    44581 tcagcagatt cagcagcacg ggggcggggg tggcgtcagt cgcagtgagg tgccacatgc
    44641 ggtcggagac gggtgtttcg taggcggcca cggtccatgc ggtctcgcgg gcctgggttt
    44701 cgtggacgcg ttcgatgcgc agggtctgcg attcgtggat ggcgtgggtc gtttcatcgg
    44761 accaggtacg ccacttttcg aactcgccgt gcgtgtcgag gaagctgtcg aggagcgcgt
    44821 cgtggtcgcc ggcatcggcc aggtagacag ggacggcctc cggctcccgg cggggcggtt
    44881 cgggcttggc tgtggtggcg tcgaagacgg aacgcgctgc gatggcggcg cgttcggtgt
    44941 cggtcagggg tgccgggccg gggcgcatct cggccgcgtg gaccttctcg aaggccacca
    45001 gtgcctccgc gggtgagtcg aaggtgtcgg cgacctggcg caggtggtcc tcgccgtgca
    45061 ggtagacgga cttgccgccc gggtggaggt atgtgccgac cgcgacggtg gtgtggccgt
    45121 cgtgggcgtg ggcgtggatc aggaggtggc cgttgcggat gtcgtcgtgg atcttctgcg
    45181 cctggttgga gacctcgcgg atttcgctgc gggtgcacca ggtcatcggg tagttcggcc
    45241 aggtccattc ctcgtcgata gcctcctgga ggcgcggggt gatctcgacg gtgatgcctg
    45301 cggcggtcag gtgctgggct gcgtcggcgg cccagtaggg ctcctcgtga tcgatgcggg
    45361 ccaggaccag gacgcctgtg gcggcggcac tccagccggc agcctccaga gccatggagg
    45421 cgacgcgtgc ctgggtgccg gtcaggtggg cctgcacggc gctcgggtgc gtggggtggg
    45481 tgtcgaggcg gacatgggcg tcgatggcgg gagtcacgtg ggtgtctcat ctgttctgcg
    45541 ggtggccggg ccttcgggtc cggccaccgg cgtcctcggg agttatcggg ttgctcgtgt
    45601 ggatcgggcg gcgtgtgcgg ccgtggtggt cggcgggccg ccgcggatgg caggcgccgg
    45661 tcgccgctgc tgtggtgggg cggctctggt ggcgttctgc cagcgggtgc ggacggccgc
    45721 gatgtcggca agagcgcggc gggcgccgac gacgagctgg aagggggtgt tcgccgggtc
    45781 gccggcgtac gcctcgatgc gccgtccggt gtgctcggcc gtggccagga gggagcgctg
    45841 cagggcgcct tcgccccagt gcccgacgga tccggccggt tcgcccagca tgcgtagcac
    45901 cgtgcctggt tcacagccgt cgtccagcag gccgcgctgc tgggcttccc acaggacggt
    45961 gacggggtcg acgggctcgc ctcggcgggc gagggtggtc aggcactgcc acaggccggc
    46021 gtgcaggggc agggtgaggt cgtcggggag cagccaccgc acggcgtcga tgtcgtcagg
    46081 gcgggcggtg gcggtggcga gcagcagttg ctcctcctcg accgcctcgg tgtggtccgg
    46141 ggcgagaacg gggggcggtg ccggggtgcg ggggaggacg ccggagcgcg gggggaagcg
    46201 gtccgcgatg tcgtccacga ccgcggcaag cgtgtcggtc tcggtgagca ccgtctggac
    46261 ggggagcggg aggctggcgt cgtggacggt gtggatgagg cgttctgcgg ccgtcagcag
    46321 gcggcggcgg gcgtgctccg cctcgaccat ccgggcgtag gcgggggcgt ggcggggcca
    46381 ggggcagacc tggacgaggc tgtgcaggta ggtggcggtc agaccccgcg cctgctctcg
    46441 gcccgcggtg agcacgcggt cgagccactt ggtgttcttc gcgtgctcgg cggggtcggg
    46501 ccgcggcagg gtgctgagcg cggtgtacag ggcggcgtgc gcggcggtgg agaaggagtc
    46561 ggcggcgatg ccgctcacgt cgtccaggcg gtgcgggtcg aggaggaggg ctccgaggag
    46621 ggcctgctcg gcgtggaaca ccggctgggg cggtgcgatg gcgtcgaggt cgtcttcgtc
    46681 gggttcgggg gtgtggggca tcaggcggcg agggtgaagt cgtcggggtc gagggcgacg
    46741 ccgaggtgcg gggcgaggag gtggccggcg agcagcgggg gaacggcgtt gccgatctgg
    46801 gagaactgct ggcccttgtt gccggcccag gggtagtcgg cggggaaggt ctgcaggagg
    46861 ccggcctcgc gggcggtgat ccggatcggc tcgggaacgg ccggcacctc ggcttcttcg
    46921 gctggcggtg tggcgggttc ggcgacccag gtgcactcgt tcgcgcggtg cccgaagaac
    46981 agcgtgccag ctggctcctg gatggaccgg acggtggcat tggcctggtt gttgctgcgc
    47041 agggaccaag accagcggtg gggctcggcg gtgaaagtgg gcgccggagc gtcggcggca
    47101 cggctttctc ggatgcggtg ccgggccgcc catccggtgc cttcgcggca ggactgcaga
    47161 acgcccctgt ccggccgggg catccaagtg ccgcgcttcc gggcgtcgga cagcgtcttg
    47221 cgggagcccg acgggaacgg ctcgggcccg cctccgggcc cacctcctgc gcagacggtg
    47281 ggaacgggcc gatcggtcgc gccccatccc agggcttcgg ccatgctgac ccagcgggca
    47341 cggcccggac cgaacagcga ttccggctcg gcgagctggg cgtgcgtggg cgtgggcggc
    47401 tgcgccgtac ggacgcggga ggccagcagg atcgcccgct tcctggtctg cgggacgccg
    47461 aagtcggcgg cgttgaggat cccgtaccag acggaaaacc cccacctgcg caggacggcg
    47521 gcgtactgct tccacagggg cagcacgtcc ggtacttcct ccatggccac ccagtcgggc
    47581 tcgcccaccg tattcagggc gtacaggtag cgcatcggct cggcggcgag cagggagcgc
    47641 tcgtcacggc aggcggagag gaggcgctcg cgggtgtcgc gcccggcggc caggtcttcg
    47701 actgctgcgt gcacgagcgg ctggtcgacc aggccgaggc gcttgccggc catgctccac
    47761 gcctgacacg gcggcgaggc gatcaccccg cgggtgcggc cgatgaacgg ccaggctgga
    47821 tacctcgcca catcgcatcg gatggtcaac tgccccgccg cagcgcgggt cttgcacgcc
    47881 cactgatccc attccaggcc gatgtcgcgc atgccaagga catgcactgc cctgctccag
    47941 ccgcccggcc ccgcgaagag gtcgaggatc acgtggccag cccgaagtcg tcctgcgtca
    48001 gcgcgtcggc gtcaccgcgg cacgcccagg gcgagcagcc gtcctcgaca ccgttctcca
    48061 gcacgtcggc gtcgcccagc tcaggctgta gggcggcccg ctcggcagcc gtgacgtgat
    48121 cgatgggggc ttcgctgagc ggga
//
