LOCUS       NC_003888              31208 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    RefSeq; complete genome.
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces
            albidoflavus group.
REFERENCE   1  (bases 1 to 8667507)
  AUTHORS   Hsiao,N.H. and Kirby,R.
  TITLE     Comparative genomics of Streptomyces avermitilis, Streptomyces
            cattleya, Streptomyces maritimus and Kitasatospora aureofaciens
            using a Streptomyces coelicolor microarray system
  JOURNAL   Antonie Van Leeuwenhoek 93 (1-2), 1-25 (2008)
   PUBMED   17588127
REFERENCE   2  (bases 1 to 8667507)
  AUTHORS   Bentley,S.D., Chater,K.F., Cerdeno-Tarraga,A.M., Challis,G.L.,
            Thomson,N.R., James,K.D., Harris,D.E., Quail,M.A., Kieser,H.,
            Harper,D., Bateman,A., Brown,S., Chandra,G., Chen,C.W., Collins,M.,
            Cronin,A., Fraser,A., Goble,A., Hidalgo,J., Hornsby,T., Howarth,S.,
            Huang,C.H., Kieser,T., Larke,L., Murphy,L., Oliver,K., O'Neil,S.,
            Rabbinowitsch,E., Rajandream,M.A., Rutherford,K., Rutter,S.,
            Seeger,K., Saunders,D., Sharp,S., Squares,R., Squares,S., Taylor,K.,
            Warren,T., Wietzorrek,A., Woodward,J., Barrell,B.G., Parkhill,J. and
            Hopwood,D.A.
  TITLE     Complete genome sequence of the model actinomycete Streptomyces
            coelicolor A3(2)
  JOURNAL   Nature 417 (6885), 141-147 (2002)
   PUBMED   12000953
REFERENCE   3  (bases 1 to 8667507)
  AUTHORS   Redenbach,M., Kieser,H.M., Denapaite,D., Eichner,A., Cullum,J.,
            Kinashi,H. and Hopwood,D.A.
  TITLE     A set of ordered cosmids and a detailed genetic and physical map for
            the 8 Mb Streptomyces coelicolor A3(2) chromosome
  JOURNAL   Mol. Microbiol. 21 (1), 77-96 (1996)
   PUBMED   8843436
REFERENCE   4  (bases 1 to 8667507)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2002) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
  REMARK    Direct Submission
REFERENCE   5  (bases 1 to 8667507)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2002) Sanger Institute, Wellcome Trust Genome
            Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
  REMARK    Direct Submission
COMMENT     ##antiSMASH-Data-START##
            Version     :: 8.0.1
            Run date    :: 2025-05-26 12:13:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start :: 6833314
            Orig. end   :: 6864522
            ##antiSMASH-Data-END##
            REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..31208
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="20"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..31208
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31208
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:17208]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..17208
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     misc_feature    207..220
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.79"
                     /tool="antismash"
     misc_feature    207..220
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     misc_feature    952..966
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     misc_feature    972..995
                     /gene_synonym="SC2H4.01; SC9G1.09"
                     /locus_tag="SCO6219"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     misc_feature    complement(1011..1023)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.33"
                     /tool="antismash"
     misc_feature    complement(1510..1525)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.42"
                     /tool="antismash"
     regulatory      2733..2737
                     /note="possible RBS upstream of SC2H4.02"
                     /regulatory_class="ribosome_binding_site"
     gene            2743..9294
                     /db_xref="GeneID:1101661"
                     /gene_synonym="SC2H4.02"
                     /locus_tag="SCO6220"
     CDS             2743..9294
                     /codon_start=1
                     /db_xref="GeneID:1101661"
                     /gene_synonym="SC2H4.02"
                     /locus_tag="SCO6220"
                     /note="SC2H4.02, unknown, len: 2183; very limited
                     similarity to proteins of the RHS family e.g. WAPA_BACSU
                     wall-associated protein precursor (2334 aa), fasta scores;
                     opt: 141 z-score: 296.8 E(): 2.7e-09, 23.4% identity in
                     1237 aa overlap, and RHSA_ECOLI RHSA protein precursor
                     (1377 aa), fasta scores; opt: 135 z-score: 222.4 E():
                     3.8e-05, 23.0% identity in 1016 aa overlap. Contains
                     possible membrane anchor around aa 1900. Alternative start
                     at aa 27 would give N-terminal signal sequence"
                     /product="hypothetical protein"
                     /protein_id="NP_630321.1"
                     /transl_table=11
                     /translation="MRHHPLGVPGAGTGPGPHRRRAVRPWMRRVSAVVGIALLPGLLAP
                     AATADDVDPLGRPELSTPRAQHVAPFKARPDARTAAVVRDSARADQSAAGRAVKDRSRG
                     TSWPTAGSARLTASGGAADEAAPGRLPVTLAPPAAKKAKRADRVKVDVLDQKAARRLGV
                     KGVVLKVTGPADGGAARLGIDYSAFAAAYGGDWAGRLQVLRLPDCTTACPPATPVKFTN
                     ERGDERLTADLAFAPKAASGQTMTLALAAGTASADGDYKATPLAPSSTWEAGGSSGSFT
                     WSYPLKAPEPAAGEAPKLEISYDSGSVDGRTSTSNNQGTEVGEGFDITSSFIERKYGSC
                     TDDGHADRHDLCWKYDNASLVLNGKATELVKDDTTGQWRLKNDDASKVTHSTGADNGDD
                     NGEYWTVTTGDGTRFVFGQNKLDGAAADVRTKSVWTVPVFGDDEGEPGYADGTGFTSRD
                     EKQAWRWNLDYAEDTHGNATTYWYEDETNNYDKLGDDDTGTSYVRGGYLKEIRYGQRAG
                     ALFSGTPQASHRIVLGHDERCLASGTGCDALTEDTRDNWPDVPFDRICKDGDKCPYLDS
                     PSFFTRKMLTSVSTYAWDAAAATPAFSPVDTWTLEHLYLDPGDTGDSTDQSLWLDEIKH
                     TGKRGTDLSLDAVKFSHVFMPNRVDGPSDDILSFERPRLRTVVSETGAQTIVDYLPADC
                     VAGQTMPKADENTKRCFPVYWSPYGQEEPILDWFQKYPVSSVRTTDPLGGSEAVQHTYE
                     YSGGGAWHYNDDPLTPAKERTWSQWRGYGKVTHYTGPSGGTRAKTVTVYLRGMDGDRVL
                     GGDGKTPDPDRRRKAEVSGVTAAAVTDSDQLAGFQRESVAYDGDKEVSGTVNDPWSKRT
                     ATQHKSYADTEAYYVRVGASHARTRITSRLNPYDRVRTTRTGYDDYGMPVSVEDLGDDS
                     VTGDEKCTRTWYARNDAAGLTALVSRTRIVGRACSVTDSALDLPADAARPGDVVSDKAT
                     AYDTTTWSATQKPTKGDARWSGRAKGYGGDDRPLWQTTAVTDYDTLGRPVQVRNTDDVI
                     TSKTEYQPPAAGPLTSTTVVNAKGHRTTTVKDFALGADLKVTDANGKVTESAYDSLGRV
                     TSVWLPNRSRALGKTANYVYGYSVKSTSLPWVSSATLNGDGSGYRTTYEIYDSLLRTRQ
                     VQAPSAQGGRVIAQTLYDGRGLPVTAQADIWDDTAAPAGKIVQIDGGQAPRQTDSVYDG
                     MGRVTKAVTKSYGVTEWAVDTAYRGDLVLTGAPEGGSANAVVTDAFGRTVERRDYAGTQ
                     PAGTDYMTTRYAFDAADRQKSITAHDRSAWTYTYDLFGRQVSVTDPDKGTTVTEYDALD
                     RAVKSTDGRGEVLLFEYDVLGRKTGMWQSAKTGANKLAAWSFDTLAKGQQDTAVRYEGG
                     ETGRAYTQKVTRYDPLYKVTNNELTLPANDPLVAAGVPARLAFSTGYNLDGTVKQAAAP
                     AVAGLSAETVSYTYDGLGQVLTAKGTTGYLQQAAYSPLGDLRQMTLATDPTGAKKVYLN
                     NDYEAGTRRLTRSYVTDDVHGFMLQELKYQQDDAGNITSVSDATTLGGTGKADHQCFTY
                     DGHRRLSEAWTPETADCSTSGRTVAGLGGAAPYWTSYQYDDSGLRSKQTEHRMSGDDVT
                     TEYEYGTAEGQPHALSATVTGAENASYTYDETGNTETRPGVRATQTLDWNAEGRLAGVS
                     EPAAGGKPATGTAYVYDAGGDLLIRRPTTTDGETVLYLGTTEVHLKVSGNGAAKALSGA
                     RTYKAGSAVIAVRTSTAGVSGTKLTFLAGDHHGTSGLAINADTLAFAKRWSTPFGAPRG
                     TASGAWPDDRGFLGKPADAATGLTQLGARQYDPDTGRFLSVDPLLEPDKPNTLNGYAYA
                     SNSPVTNSDPSGTSDGLGGLLGAIGAIIGGVVGAVIGAVGAAITAVGSLGGGGGGGWGG
                     TAPTSSGGWTQPLTKQWTPGATYNFITKSWDLPFNPPSQSLEEMLASMPDWGIVSDPKA
                     ANRWETSRSLFFGWLWGGGYPLREHQDFRGGDAFTSILAQDETISGLRSKMVGQARKGT
                     KGAFAKEVGFQYVDEGPEPGSPWYKFNSLRGAAKDIAGVLTNGAVGTGNQADAFLGTYS
                     GKARISSINKKEGSVTLKFSAWNGSDWRSATHVVPRSWNPAFEDTFGAAVREDFSWEEK
                     WPINECVNYSEWLE"
     PFAM_domain     6631..6738
                     /aSDomain="RHS_repeat"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05593.17"
                     /description="RHS Repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6220_0723"
                     /evalue="2.70E-05"
                     /label="SCO6220"
                     /locus_tag="SCO6220"
                     /protein_end="1332"
                     /protein_start="1296"
                     /score="24.7"
                     /tool="antismash"
                     /translation="FDAADRQKSITAHDRSAWTYTYDLFGRQVSVTDPDK"
     aSDomain        6658..6747
                     /aSDomain="TIGR01643"
                     /aSTool="tigrfam"
                     /description="YD_repeat_2x: YD repeat (two copies)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6220_0092"
                     /evalue="5.00E-04"
                     /identifier="TIGR01643"
                     /label="SCO6220"
                     /locus_tag="SCO6220"
                     /protein_end="1335"
                     /protein_start="1305"
                     /score="18.5"
                     /tool="antismash"
                     /translation="ITAHDRSAWTYTYDLFGRQVSVTDPDKGTT"
     aSDomain        8164..8400
                     /aSDomain="TIGR03696"
                     /aSTool="tigrfam"
                     /description="Rhs_assc_core: RHS repeat-associated core
                     domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6220_0091"
                     /evalue="2.50E-18"
                     /identifier="TIGR03696"
                     /label="SCO6220"
                     /locus_tag="SCO6220"
                     /protein_end="1886"
                     /protein_start="1807"
                     /score="64.3"
                     /tool="antismash"
                     /translation="TPFGAPRGTASGAWPDDRGFLGKPADAATGLTQLGARQYDPDTGR
                     FLSVDPLLEPDKPNTLNGYAYASNSPVTNSDPSG"
     stem_loop       9320..9355
                     /note="hairpin loop with 17/17 bp stem"
     gene            9386..9847
                     /db_xref="GeneID:1101662"
                     /gene_synonym="SC2H4.03"
                     /locus_tag="SCO6221"
     CDS             9386..9847
                     /codon_start=1
                     /db_xref="GeneID:1101662"
                     /gene_synonym="SC2H4.03"
                     /locus_tag="SCO6221"
                     /note="SC2H4.03, possible lipoprotein, len: 153 aa;
                     contains possible N-terminal signal sequence with
                     appropriately positioned PS00013 Prokaryotic membrane
                     lipoprotein lipid attachment site"
                     /product="lipoprotein"
                     /protein_id="NP_630322.1"
                     /transl_table=11
                     /translation="MLKTPFAPAVRWTAAVLITLLAATACDDTGARAATVPADRVTGAW
                     QAGGGTALTLSADRTFTASGLDSGKLAGTGCPGGDTGGDWAFFADDGDGLYMTSPRARS
                     GSEIGLSFAEQSDEPCRLTLTVVDDGDTLCATSDPETPCDLGVRFTRKD"
     misc_feature    9431..9463
                     /gene_synonym="SC2H4.03"
                     /locus_tag="SCO6221"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site"
     gene            complement(9858..11066)
                     /db_xref="GeneID:1101663"
                     /gene_synonym="SC2H4.04c"
                     /locus_tag="SCO6222"
     CDS             complement(9858..11066)
                     /EC_number="2.6.1.2"
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-393). E-value:
                     2.5e-55. Score: 180.0. Matches aSDomain:
                     nrpspksdomains_SCO6222_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GeneID:1101663"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC2H4.04c"
                     /locus_tag="SCO6222"
                     /note="broad specificity; family IV; in Corynebacterium
                     glutamicum this protein can use glutamate, 2-aminobutyrate,
                     and aspartate as amino donors and pyruvate as the acceptor"
                     /product="aminotransferase AlaT"
                     /protein_id="NP_630323.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.1e-53, bitscore:
                     180.1, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 4.6e-06, bitscore:
                     24.6, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.9e-07,
                     bitscore: 28.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFRQSNKLSEVCYEIRGPVIEHANALEEAGHSVLRLNTGNPALF
                     GFEAPEEIVQDMIRMLPRAHGYTDSRGILSARRAVAQRYQALGLEVDVDDVFLGNGVSE
                     LISMAVQALLEDGDEVLIPAPDFPLWTAVTTLAGGKAVHYLCDEQAEWYPDLADMEAKI
                     TDRTKAVVIINPNNPTGAVYPKEIVEGILDLARRHGLMVLADEIYDQILYDDAVHHSAA
                     SLAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGPKQHARDYLEGLTMLASMRLCANAPAQ
                     YAIQAALGGRQSIRELTAPGGRLHEQRDVAWEKLNEIPGISCVKPKGALYAFPRIDPAV
                     HKIHDDERFVLDLLLREKIQVVQGTGFNWPSPDHFRILTLPHAEDLEAAIGRIGRFLSG
                     YRQ"
     misc_feature    complement(9870..11051)
                     /gene_synonym="SC2H4.04c"
                     /locus_tag="SCO6222"
                     /note="Pfam match to entry PF00155 aminotran_1,
                     Aminotransferases class-I, score 136.00, E-value 6.9e-37"
     aSDomain        complement(9888..10967)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO6222_Aminotran_1_2.1"
                     /evalue="2.50E-55"
                     /label="SCO6222_Aminotran_1_2.1"
                     /locus_tag="SCO6222"
                     /protein_end="393"
                     /protein_start="33"
                     /score="180.0"
                     /tool="antismash"
                     /translation="VLRLNTGNPALFGFEAPEEIVQDMIRMLPRAHGYTDSRGILSARR
                     AVAQRYQALGLEVDVDDVFLGNGVSELISMAVQALLEDGDEVLIPAPDFPLWTAVTTLA
                     GGKAVHYLCDEQAEWYPDLADMEAKITDRTKAVVIINPNNPTGAVYPKEIVEGILDLAR
                     RHGLMVLADEIYDQILYDDAVHHSAASLAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGP
                     KQHARDYLEGLTMLASMRLCANAPAQYAIQAALGGRQSIRELTAPGGRLHEQRDVAWEK
                     LNEIPGISCVKPKGALYAFPRIDPAVHKIHDDERFVLDLLLREKIQVVQGTGFNWPSPD
                     HFRILTLPHAEDLEAAIGRI"
     PFAM_domain     complement(9888..10967)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00155.24"
                     /db_xref="GO:0009058"
                     /db_xref="GO:0030170"
                     /description="Aminotransferase class I and II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6222_0724"
                     /evalue="7.80E-53"
                     /gene_ontologies="GO:0009058: biosynthetic process"
                     /gene_ontologies="GO:0030170: pyridoxal phosphate binding"
                     /label="SCO6222"
                     /locus_tag="SCO6222"
                     /protein_end="393"
                     /protein_start="33"
                     /score="180.1"
                     /tool="antismash"
                     /translation="VLRLNTGNPALFGFEAPEEIVQDMIRMLPRAHGYTDSRGILSARR
                     AVAQRYQALGLEVDVDDVFLGNGVSELISMAVQALLEDGDEVLIPAPDFPLWTAVTTLA
                     GGKAVHYLCDEQAEWYPDLADMEAKITDRTKAVVIINPNNPTGAVYPKEIVEGILDLAR
                     RHGLMVLADEIYDQILYDDAVHHSAASLAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGP
                     KQHARDYLEGLTMLASMRLCANAPAQYAIQAALGGRQSIRELTAPGGRLHEQRDVAWEK
                     LNEIPGISCVKPKGALYAFPRIDPAVHKIHDDERFVLDLLLREKIQVVQGTGFNWPSPD
                     HFRILTLPHAEDLEAAIGRI"
     regulatory      complement(11078..11082)
                     /note="possible RBS upstream of SC2H4.04c"
                     /regulatory_class="ribosome_binding_site"
     gene            11154..11804
                     /db_xref="GeneID:1101664"
                     /gene_synonym="SC2H4.05"
                     /locus_tag="SCO6223"
     CDS             11154..11804
                     /codon_start=1
                     /db_xref="GeneID:1101664"
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="SC2H4.05"
                     /locus_tag="SCO6223"
                     /note="SC2H4.05, unknown, len: 216 aa; similar to
                     hypothetical proteins from many organisms e.g. TR:P71983
                     (EMBL:Z81360) Mycobacterium tuberculosis MTCY04C12.10C (236
                     aa), fasta scores; opt: 276 z-score: 307.9 E(): 6.6e-10,
                     46.0% identity in 100 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_630324.1"
                     /transl_table=11
                     /translation="MSPRRSYDQYCSAARALDAVGDRWTLLIVRELLAGPRRYTDLHAD
                     LPGVSTDVLASRLKDMEREGLTTRRRLPPPGAAYVYELTARGRGLLPVLEALGAWGAGE
                     LGERRPTDAVRAHWFALPLLRALREAGAGEGLVEVRLEEGDFHLYADARAEGEDGPVYG
                     EGPAPGEPDARLVLDAVTCAALGRGETGLREAVRDGRVQVTGDGTVAKALREG"
     PFAM_domain     11211..11465
                     /aSDomain="HxlR"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01638.20"
                     /description="HxlR-like helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6223_0725"
                     /evalue="2.50E-21"
                     /label="SCO6223"
                     /locus_tag="SCO6223"
                     /protein_end="104"
                     /protein_start="19"
                     /score="75.4"
                     /tool="antismash"
                     /translation="VGDRWTLLIVRELLAGPRRYTDLHADLPGVSTDVLASRLKDMERE
                     GLTTRRRLPPPGAAYVYELTARGRGLLPVLEALGAWGAGE"
     gene            complement(11858..12673)
                     /db_xref="GeneID:1101665"
                     /gene_synonym="SC2H4.06c"
                     /locus_tag="SCO6224"
     CDS             complement(11858..12673)
                     /codon_start=1
                     /db_xref="GeneID:1101665"
                     /gene_synonym="SC2H4.06c"
                     /locus_tag="SCO6224"
                     /note="SC2H4.06c, probable hypothetical protein, len: 271
                     aa; contains N-terminal signal sequence"
                     /product="hypothetical protein"
                     /protein_id="NP_630325.1"
                     /transl_table=11
                     /translation="MRFTRALSAAVVLLGLAAAPAAADSSPSASPSGDGDAPTTAGTSF
                     RTATEFEQGQAATASGAAGDYLYWSFPADAGQRPTVKATVKLPETHAAQTWRVDVYDGL
                     RRRQACQWGAQARTADAGTSSVELACVLRTVRAWTEPWANDPLPGTYYVRLTAVNVPTS
                     DLGVPVSAEVRADSKDIGGAAAVDGSLAEPLVPGIAVTSGTGSASEDDEDDRGAVLSAI
                     EPEDGWSSGWWSDRWVWSGIGAVLAALAGIGGYALTRGSGRPTRVPPGA"
     gene            complement(12673..13938)
                     /db_xref="GeneID:1101666"
                     /gene_synonym="SC2H4.07c"
                     /locus_tag="SCO6225"
     CDS             complement(12673..13938)
                     /codon_start=1
                     /db_xref="GeneID:1101666"
                     /gene_synonym="SC2H4.07c"
                     /locus_tag="SCO6225"
                     /note="SC2H4.07c, probable hypothetical protein, len: 421
                     aa; similar in C-terminus to B. subtilis TR:P70960
                     (EMBL:Z81356;) hypothetical protein ywmC precursor (227
                     aa), fasta scores; opt: 319 z-score: 219.2 E(): 5.8e-05,
                     29.6% identity in 216 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_630326.1"
                     /transl_table=11
                     /translation="MITRTRLAAGACALLAALAAGMAFPAGASAGEPTGEDAPKVDLVL
                     DVSGSMRTRDIDGGTRMAAAKQAFNEVLDATPEEVRLGIRTLGADYPGDDRKTGCKDTA
                     QLYPVGPLDRTEAKTAVATLSPTGWTPIGPALLKAADDLDGGDGSKRIVLISDGEDTCA
                     PLDPCEVAREIAAKGIGLTIDTLGLVPNTKMRQQLSCIAEATGGTYTSVEHTDELTDKV
                     NQLVDRAADPVVTPVATEGADACAKAPTLKSGLYTDREEFGQQRWYRVDVEPGQELRAS
                     VSVGADRAVNPSYGVLLRAVTVHGREIVRGEAAGNGRTDVLSTGLRYPKAKSDEDDAPA
                     EAVCLQVTNSFSVASGVKTSPGLPLELTVDVVDGPGDSDDVAAFGLGRGWWLLGLLVLV
                     GFVAGLLWGWLSRWRFAIWRTN"
     regulatory      complement(12682..12686)
                     /gene_synonym="SC2H4.07c"
                     /locus_tag="SCO6225"
                     /note="possible RBS upstream of SC2H4.06c"
                     /regulatory_class="ribosome_binding_site"
     PFAM_domain     complement(13279..13812)
                     /aSDomain="VWA"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00092.31"
                     /description="von Willebrand factor type A domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6225_0726"
                     /evalue="2.60E-09"
                     /label="SCO6225"
                     /locus_tag="SCO6225"
                     /protein_end="220"
                     /protein_start="42"
                     /score="37.7"
                     /tool="antismash"
                     /translation="LVLDVSGSMRTRDIDGGTRMAAAKQAFNEVLDATPEEVRLGIRTL
                     GADYPGDDRKTGCKDTAQLYPVGPLDRTEAKTAVATLSPTGWTPIGPALLKAADDLDGG
                     DGSKRIVLISDGEDTCAPLDPCEVAREIAAKGIGLTIDTLGLVPNTKMRQQLSCIAEAT
                     GGTYTSVEHTDELTD"
     regulatory      complement(13946..13949)
                     /note="possible RBS upstream of SC2H4.07c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(14001..15527)
                     /db_xref="GeneID:1101667"
                     /gene_synonym="SC2H4.08c"
                     /locus_tag="SCO6226"
     CDS             complement(14001..15527)
                     /codon_start=1
                     /db_xref="GeneID:1101667"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SC2H4.08c"
                     /locus_tag="SCO6226"
                     /note="SC2H4.08c, unknown, len: 508 aa; some similarity to
                     Rhizobium sp. NGR234 plasmid pNGR234a hypothetical protein
                     Y4XN_RHISN (628 aa), fasta scores; opt: 116 z-score: 207.6
                     E(): 0.00026, 26.4% identity in 641 aa overlap. Also some
                     similarity to divergent CDS SC2H4.09 (E(): 0.00044, 29.1%
                     identity in 553 aa overlap)"
                     /product="hypothetical protein"
                     /protein_id="NP_630327.1"
                     /sec_met_domain="IucA_IucC (E-value: 6e-32, bitscore:
                     109.9, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRPPSAAAEVAEELAAVRPALIARFAAERPGARAAVLSRLWRAL
                     AFEPLPWIEGRERSGDGLVLRLRDGRRLSGPPADPYRTDAYVPVVRLDEVAYDDPERLL
                     TDLAVPHSASFAAELGHSAASLALSRAAQPRAAREGAPGNHPDEWPDSGWGWERRVVDG
                     HPYHPGCRARPGFSVAEQLAYGPEHGPVVELGLVPVPAAECLVTGVWPGELRDGARVLV
                     PVHPWQAAHVLKQSYATGPAARPLMSLRTLAVPGSVHVKTALSARLTSSVRDISVASIA
                     ASADLSSFGERLAARLDGLLHVTRTLGAATAHSPDLAAVLREAPEVYASGGEHVVPVAA
                     LATTGLPRSAAWLAGFARLALTVGLRALELGVALEAHGQNLLVVLSAAGDPLRLVYRDL
                     ADIRVSPARLARHGIAAHGLPARVRTDEPLALRRKLFGSLVGGALAATAGSGPALRAAL
                     AAAVPELPRTEDVVALCEEPLPVKALTVMRTSPGIAGDLWTELPNPLRWR"
     PFAM_domain     complement(14190..14477)
                     /aSDomain="FhuF"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF06276.15"
                     /description="Ferric iron reductase FhuF-like transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6226_0728"
                     /evalue="7.70E-12"
                     /label="SCO6226"
                     /locus_tag="SCO6226"
                     /protein_end="446"
                     /protein_start="350"
                     /score="46.0"
                     /tool="antismash"
                     /translation="AWLAGFARLALTVGLRALELGVALEAHGQNLLVVLSAAGDPLRLV
                     YRDLADIRVSPARLARHGIAAHGLPARVRTDEPLALRRKLFGSLVGGALAA"
     PFAM_domain     complement(14502..15062)
                     /aSDomain="IucA_IucC"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04183.15"
                     /db_xref="GO:0019290"
                     /description="IucA / IucC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6226_0727"
                     /evalue="1.20E-25"
                     /gene_ontologies="GO:0019290: siderophore biosynthetic
                     process"
                     /label="SCO6226"
                     /locus_tag="SCO6226"
                     /protein_end="342"
                     /protein_start="155"
                     /score="90.6"
                     /tool="antismash"
                     /translation="WERRVVDGHPYHPGCRARPGFSVAEQLAYGPEHGPVVELGLVPVP
                     AAECLVTGVWPGELRDGARVLVPVHPWQAAHVLKQSYATGPAARPLMSLRTLAVPGSVH
                     VKTALSARLTSSVRDISVASIAASADLSSFGERLAARLDGLLHVTRTLGAATAHSPDLA
                     AVLREAPEVYASGGEHVVPVAALA"
     regulatory      complement(15535..15539)
                     /note="possible RBS upstream of SC2H4.08c"
                     /regulatory_class="ribosome_binding_site"
     gene            15655..17208
                     /db_xref="GeneID:1101668"
                     /gene_synonym="SC2H4.09"
                     /locus_tag="SCO6227"
     CDS             15655..17208
                     /codon_start=1
                     /db_xref="GeneID:1101668"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SC2H4.09"
                     /locus_tag="SCO6227"
                     /note="SC2H4.09, unknown, len: 517 aa; some similarity to
                     Rhizobium sp. NGR234 plasmid pNGR234a hypothetical protein
                     Y4XN_RHISN (628 aa), fasta scores; opt: 148 z-score: 254.8
                     E(): 6e-07, 25.9% identity in 495 aa overlap. Also weak
                     similarity to S. coelicolor SC4H2.21 (E(): 1.8e-06, 33.2%
                     identity in 581 aa overlap) and to divergent CDS SC2H4.08c
                     (E(): 0.0012, 29.1% identity in 553 aa overlap)"
                     /product="hypothetical protein"
                     /protein_id="NP_630328.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.7e-44, bitscore:
                     151.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERVDLLPPPTGADAPLPDGAAAQDDVARRADAHAAVPLLNCLLR
                     EVAEPLPGPGARPVYRLPGGRLLRVRPGRRPAEPEVRTQGGWHRVDHAELVKLVAEALR
                     RHTGVPNHELPTEMTDSRDAMAALLTARARATPPADPYLRSEQALLTGHTHHPAPKARG
                     GGPHAGWLPYAPEAHARFPLALLAVREDTVVDEGDTAALDALGKAPPGYRLLPAHPWQL
                     ELTAPALAPAFADGRLVRVGTTGFFAWPTAAIRTVYAPEYLPGRDLFLKFSLDVRVTND
                     IRRLWRHDLMRLRRTDTAVTEAFASVGPPAAWLADRGHRTADFAFEELAVVVRDGLRDH
                     LLPGATPLLAAALVEGFPGSPLTATADPAAWWEAYLAAVVPPVLTAFADDGVVLEAHLQ
                     NTLVAVDATGMPVQALFRDAEGVKLLPDTPRAAGWERLVYCLVVNHLYEIAAALAEHHP
                     GLDPWPAVRRELARHDIPEIPALLTAPALPAKTNLLLRWTGADGADARYRPLANPLRGA
                     "
     PFAM_domain     16078..16716
                     /aSDomain="IucA_IucC"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04183.15"
                     /db_xref="GO:0019290"
                     /description="IucA / IucC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6227_0729"
                     /evalue="1.00E-33"
                     /gene_ontologies="GO:0019290: siderophore biosynthetic
                     process"
                     /label="SCO6227"
                     /locus_tag="SCO6227"
                     /protein_end="354"
                     /protein_start="141"
                     /score="117.0"
                     /tool="antismash"
                     /translation="YLRSEQALLTGHTHHPAPKARGGGPHAGWLPYAPEAHARFPLALL
                     AVREDTVVDEGDTAALDALGKAPPGYRLLPAHPWQLELTAPALAPAFADGRLVRVGTTG
                     FFAWPTAAIRTVYAPEYLPGRDLFLKFSLDVRVTNDIRRLWRHDLMRLRRTDTAVTEAF
                     ASVGPPAAWLADRGHRTADFAFEELAVVVRDGLRDHLLPGATPLLAAALV"
     PFAM_domain     16762..17163
                     /aSDomain="FhuF"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF06276.15"
                     /description="Ferric iron reductase FhuF-like transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6227_0730"
                     /evalue="7.30E-24"
                     /label="SCO6227"
                     /locus_tag="SCO6227"
                     /protein_end="503"
                     /protein_start="369"
                     /score="85.1"
                     /tool="antismash"
                     /translation="AWWEAYLAAVVPPVLTAFADDGVVLEAHLQNTLVAVDATGMPVQA
                     LFRDAEGVKLLPDTPRAAGWERLVYCLVVNHLYEIAAALAEHHPGLDPWPAVRRELARH
                     DIPEIPALLTAPALPAKTNLLLRWTGADGA"
     gene            17276..17890
                     /db_xref="GeneID:1101669"
                     /gene_synonym="SC2H4.10"
                     /locus_tag="SCO6228"
     CDS             17276..17890
                     /codon_start=1
                     /db_xref="GeneID:1101669"
                     /gene_synonym="SC2H4.10"
                     /locus_tag="SCO6228"
                     /note="SC2H4.10, unknown, len: 204 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_630329.1"
                     /transl_table=11
                     /translation="MADMDAFRDEIARWAAGGAGDTAAELAAGLGLRTAVLLEGPSDLA
                     AVQALAAREDRDLAAEGVAVVSMGGAMSVGRYAGLLGPPGLGLRLTGLCDAREEPFYVR
                     GWQRAGAARDFHVCVADLEDEMIRALGPARVEEVIRSEDELRPWQTFLAQPAQHGRPRE
                     QQLRRFLSTKKGRKIRYGSLLVEALDGGRPPAPLADLLAGL"
     PFAM_domain     17375..17521
                     /aSDomain="OLD-like_TOPRIM"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF20469.1"
                     /description="Overcoming lysogenization defect
                     protein-like, TOPRIM domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6228_0731"
                     /evalue="1.10E-05"
                     /label="SCO6228"
                     /locus_tag="SCO6228"
                     /protein_end="82"
                     /protein_start="33"
                     /score="26.0"
                     /tool="antismash"
                     /translation="TAVLLEGPSDLAAVQALAAREDRDLAAEGVAVVSMGGAMSVGRYA
                     GLLG"
     gene            complement(17898..18779)
                     /db_xref="GeneID:1101670"
                     /gene_synonym="SC2H4.11c"
                     /locus_tag="SCO6229"
     CDS             complement(17898..18779)
                     /codon_start=1
                     /db_xref="GeneID:1101670"
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /gene_synonym="SC2H4.11c"
                     /locus_tag="SCO6229"
                     /note="SC2H4.11c, probable sugar transport system permease,
                     len: 293 aa; similar to many e.g. MALD_STRPN maltodextrin
                     transport system permease (277 aa), fasta scores; opt: 394
                     z-score: 585.4 E(): 2.3e-25, 29.1% identity in 268 aa
                     overlap. Contains PS00402 Binding-protein-dependent
                     transport systems inner membrane comp signature. Contains
                     Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 58.30, E-value 1.6e-13"
                     /product="sugar transport system permease"
                     /protein_id="NP_630330.1"
                     /transl_table=11
                     /translation="MTLTAPVRPQERPRSRPRSRPRISTALTYLSLVVASAVVLLPLLV
                     VFLTSLKSYGEVSDGQGALAPPDDWLNFSNYATAFSDGHLLQAFGNTAFILLFSITGTV
                     IIGSMTAYAIDRFDFRLKKLVMALFLIATLVPAVTTQVATFQVVNGFGLFNTRWAPILL
                     YMGTDIVAIYIFLQFIRGIPRSLDEAARLDGANSFTIYRKIIFPLLKPAVATVVIIKGI
                     TTYNDFYIPFLYMPDEDLGTMSTALFRFKGPFGAHWENISAGAVLVIVPTLVIFLFLQR
                     YIYNGFAQGATK"
     PFAM_domain     complement(17925..18470)
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00528.25"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6229_0732"
                     /evalue="1.30E-14"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO6229"
                     /locus_tag="SCO6229"
                     /protein_end="285"
                     /protein_start="103"
                     /score="54.5"
                     /tool="antismash"
                     /translation="VIIGSMTAYAIDRFDFRLKKLVMALFLIATLVPAVTTQVATFQVV
                     NGFGLFNTRWAPILLYMGTDIVAIYIFLQFIRGIPRSLDEAARLDGANSFTIYRKIIFP
                     LLKPAVATVVIIKGITTYNDFYIPFLYMPDEDLGTMSTALFRFKGPFGAHWENISAGAV
                     LVIVPTLVIFLFLQRYIYN"
     misc_feature    complement(18018..18248)
                     /gene_synonym="SC2H4.11c"
                     /locus_tag="SCO6229"
                     /note="Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 58.30, E-value 1.6e-13"
     misc_feature    complement(18159..18245)
                     /gene_synonym="SC2H4.11c"
                     /locus_tag="SCO6229"
                     /note="PS00402 Binding-protein-dependent transport systems
                     inner membrane comp signature"
     gene            complement(18776..19750)
                     /db_xref="GeneID:1101671"
                     /gene_synonym="SC2H4.12c"
                     /locus_tag="SCO6230"
     CDS             complement(18776..19750)
                     /codon_start=1
                     /db_xref="GeneID:1101671"
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /gene_synonym="SC2H4.12c"
                     /locus_tag="SCO6230"
                     /note="SC2H4.12c, probable sugar transport system permease,
                     len: 324 aa; similar to many e.g. AMYD_THETU potential
                     starch degradation products transport system permease (292
                     aa), fasta scores; opt: 479 z-score: 571.8 E(): 1.3e-24,
                     28.8% identity in 281 aa overlap. Contains Pfam match to
                     entry PF00528 BPD_transp, Binding-protein-dependent
                     transport systems inner membrane component, score 58.80,
                     E-value 1.2e-13"
                     /product="sugar transport system permease"
                     /protein_id="NP_630331.1"
                     /transl_table=11
                     /translation="MTRTASTASPPAPAAGPGRTGKRPSRHRARAGSPWRGRPLRKLTP
                     WLFLLAPLALLITFTYVPVGNMIYYSFTDWDGVSPDRDYVGAENYTEIFTRPELLRVFA
                     VSFYYLAASVVQIVIALYFAAVLSFDLRFRNLFKGILFFPYLINGVAIGFVFLYFFQDG
                     GTLDSVLSWFGAGTDHAWLGSPESANTSMAGVSVWRFTGLNFVLFLGAIQSIPGELYEA
                     AQLDGAGRWKQFRHIIAPSIRPVLSLSVILAISGSLSVFEIPYIMTGGATETSTFVIQT
                     VKYAFQFNKTGLASACAVVLLAIILLITWIQRRLVPDEKVDLV"
     regulatory      complement(18787..18793)
                     /gene_synonym="SC2H4.12c"
                     /locus_tag="SCO6230"
                     /note="posxsible RBS upstream of SC2H4.11c"
                     /regulatory_class="ribosome_binding_site"
     PFAM_domain     complement(18797..19402)
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00528.25"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6230_0733"
                     /evalue="4.20E-23"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO6230"
                     /locus_tag="SCO6230"
                     /protein_end="318"
                     /protein_start="116"
                     /score="82.2"
                     /tool="antismash"
                     /translation="IVIALYFAAVLSFDLRFRNLFKGILFFPYLINGVAIGFVFLYFFQ
                     DGGTLDSVLSWFGAGTDHAWLGSPESANTSMAGVSVWRFTGLNFVLFLGAIQSIPGELY
                     EAAQLDGAGRWKQFRHIIAPSIRPVLSLSVILAISGSLSVFEIPYIMTGGATETSTFVI
                     QTVKYAFQFNKTGLASACAVVLLAIILLITWIQRRLVPD"
     misc_feature    complement(18899..19120)
                     /gene_synonym="SC2H4.12c"
                     /locus_tag="SCO6230"
                     /note="Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 58.80, E-value 1.2e-13"
     gene            complement(19793..21115)
                     /db_xref="GeneID:1101672"
                     /gene_synonym="SC2H4.13c"
                     /locus_tag="SCO6231"
     CDS             complement(19793..21115)
                     /codon_start=1
                     /db_xref="GeneID:1101672"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC2H4.13c"
                     /locus_tag="SCO6231"
                     /note="SC2H4.13c, probable sugar transport system
                     sugar-binding lipoprotein, len: 440 aa; some similarity to
                     several, e.g. TR:Q46443 (EMBL:M57692) Thermoanaerobacterium
                     thermosulfurigenes maltose-binding protein precursor (446
                     aa), fasta scores; opt: 239 z-score: 192.4 E(): 0.0018,
                     23.5% identity in 366 aa overlap. Contains N-terminal
                     signal sequence with appropriately positioned PS00013
                     Prokaryotic membrane lipoprotein lipid attachment site
                     sugar transport system sugar-binding lipoprotein"
                     /product="sugar transport system sugar-binding lipoprotein"
                     /protein_id="NP_630332.1"
                     /transl_table=11
                     /translation="MGKRTLSVALLATTMLTVAGCGAGGGADAGETAAAPVNPDGVSGD
                     ITVLTNRTDLVEDGTMKKYAAEFNKTYPDVKVEFEGLTDYEGEVKIRMNTEDYGDVLLI
                     PSAVAKGDYPKFFAPLGETSSMEPKYRFTDKTDVGGRTYGIATFGTANGLVYNKALWKK
                     AGITDWPTTTGRFLDDLEAVKEKTGATPYYTNFKDGWPLESPWTNGVGSISCDSQASDK
                     LAAMDEPWTEGNDLNTLDTLLYDIVHEKLSEKDPATTNWESSKTLLAKGRVGSMMLGSW
                     AVNQMRDAAEAAGQNPDDIGFMPVPSQKNGTFCATLVSDYQQAVNIHSDHKEAARAWID
                     WFTEKSGYAAEEGAVSALKSEGMPETLQDYVDNDVKMIERSEAKTADVNAIDNASEIGL
                     NKPDYRKKLIDIARGVTDGSLEGYFDDLNKRWSAARQTVGS"
     PFAM_domain     complement(20078..20947)
                     /aSDomain="SBP_bac_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01547.28"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6231_0734"
                     /evalue="5.20E-32"
                     /label="SCO6231"
                     /locus_tag="SCO6231"
                     /protein_end="346"
                     /protein_start="56"
                     /score="112.2"
                     /tool="antismash"
                     /translation="EDGTMKKYAAEFNKTYPDVKVEFEGLTDYEGEVKIRMNTEDYGDV
                     LLIPSAVAKGDYPKFFAPLGETSSMEPKYRFTDKTDVGGRTYGIATFGTANGLVYNKAL
                     WKKAGITDWPTTTGRFLDDLEAVKEKTGATPYYTNFKDGWPLESPWTNGVGSISCDSQA
                     SDKLAAMDEPWTEGNDLNTLDTLLYDIVHEKLSEKDPATTNWESSKTLLAKGRVGSMML
                     GSWAVNQMRDAAEAAGQNPDDIGFMPVPSQKNGTFCATLVSDYQQAVNIHSDHKEAARA
                     WIDWFTEKS"
     misc_feature    complement(21053..21085)
                     /gene_synonym="SC2H4.13c"
                     /locus_tag="SCO6231"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site"
     regulatory      complement(21124..21129)
                     /note="possible RBS upstream of SC2H4.13c"
                     /regulatory_class="ribosome_binding_site"
     misc_feature    21172..21189
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.11"
                     /tool="antismash"
     misc_feature    complement(21301..21316)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.49"
                     /tool="antismash"
     regulatory      21375..21380
                     /note="possible RBS upstream of SC2H4.14"
                     /regulatory_class="ribosome_binding_site"
     gene            21387..23849
                     /db_xref="GeneID:1101673"
                     /gene_synonym="SC2H4.14"
                     /locus_tag="SCO6232"
     CDS             21387..23849
                     /codon_start=1
                     /db_xref="GeneID:1101673"
                     /gene_synonym="SC2H4.14"
                     /locus_tag="SCO6232"
                     /note="SC2H4.14, probable beta-mannosidase, len: 820 aa;
                     similar to several eukaryotic beta-mannosidases, e.g.
                     MANB_HUMAN beta-mannosidase precursor (EC 3.2.1.25) (879
                     aa), fasta scores; opt: 679 z-score: 909.3 E(): 0, 31.4%
                     identity in 684 aa overlap"
                     /product="beta-mannosidase"
                     /protein_id="NP_630333.1"
                     /transl_table=11
                     /translation="MKEVVPLAEGWSLRHSDDLLPAQVPGCVHTDLLAAGLIPDPFLGV
                     NESDVAWVGQRAWTYVRDLPATCTDTATAAPEHERTDLVFDGLDTAATITLNGRELGRT
                     RNMHRRHRFDVTGRHGLLEVDFASAYDEATSVRALTGERPNVYPEPFQYIRKMACGFGW
                     DWGPTLVTAGIWRPVRLERWSTARLAGVRPLVTVHGGTGRVELRVEVERTAQGAARPLA
                     VRATVGSGLAEARGAVEGTHVVLTLQVPDADLWWPRGYGGQPLYDLELALVEEAAGPGG
                     EERPLDTWHRRIGFRTVEVDRSADSHGTGFTLVVNGERVFARGVNWIPDDVFPSRITPE
                     RYRTRLRQTADAGVDLVRIWGGGIYEDDAFYDACDELGLMVWQDFLFACAAYPEEQPLR
                     GEVEAEARDNVVRLMPHPSLVLWNGNNENLWGFRDWDWEPELRGDSWGGGYYLDLLPRI
                     VAELDPTRPYTAGSPWSGSWDHHPNDPAHGTYHSWEVWNRRDYAEYRDSVPRFVSEFGW
                     QAPPAMATLRRALPGERLAPDSPGMLHHQKAEDGNGKLNRGVERHFELPEGDFDRWHYL
                     TQVVQARAIATGIEHWRSHWPVCAGTVVWQINDCWPVSSWSAIDGDGRLKPLYHELRRV
                     YADRLLTVQPGDGHGGPPVLAVVNQSAEPWQARVTLRRLRADGTEAAGRAIDVTVPARS
                     VHRRTVPQELAPAPRSAKEFLVADSEDLRSVHFCVTDRDFAYPVPHYDVAVESPVGSGT
                     GNVEVVVTAHTLVRDLLLQADRLGPDAVCDTGLRTLLPGERLRLRVTGAAETGANAVRA
                     ALFCVEPA"
     gene            23846..24874
                     /db_xref="GeneID:1101674"
                     /gene_synonym="SC2H4.15"
                     /locus_tag="SCO6233"
     CDS             23846..24874
                     /codon_start=1
                     /db_xref="GeneID:1101674"
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="SC2H4.15"
                     /locus_tag="SCO6233"
                     /note="SC2H4.15, probable transcriptional regulator, len:
                     342 aa; similar to many members of the lacI family e.g.
                     CCPA_BACME glucose-resistance amylase regulator (Bacillus
                     megaterium) (332 aa), fasta scores; opt: 448 z-score: 548.6
                     E(): 2.6e-23, 29.8% identity in 336 aa overlap. Contains
                     helix-turn-helix motif from aa 9-30 (Score 1778, +5.24 SD)
                     and Pfam matches to entry PF00356 lacI, Bacterial
                     regulatory proteins, lacI family, score 30.40, E-value
                     4.7e-07 and to entry PF00532 Peripla_BP_like, Periplasmic
                     binding proteins and LacI family, score 44.00, E-value
                     3.4e-09"
                     /product="transcriptional regulator"
                     /protein_id="NP_630334.1"
                     /transl_table=11
                     /translation="MSTPSVRVTIKDVAAAAGVSKGAVSLAFNDKPGVSDATRERIFAV
                     ARQLGWAPNSSARSLSRQSVDTVGLAICRPARLLGLEPFYMEFVSGIESVLAERDCSLL
                     LRLVGSLEEEIGLQERWWRERQVGGSILVDFHQEDPRIGPLGRIGLPAVAVGHPSLTGG
                     FPSVWTDDAAAVAEAVRYLAVLGHRRIAHVGGPRGLGHSAIRTTAFERTLSELGLDRGP
                     HVETGFSGEDGARATRSLLLSAERPTAILYDNDIMAVAGLGVAAEMGVSVPDDLSLLAW
                     DDSQLCRLTHPTLSAMSHDVHGFGAQVTRVLFDVLAGKDVTSRPVATPSLVPRASTASP
                     RS"
     misc_feature    23861..23944
                     /gene_synonym="SC2H4.15"
                     /locus_tag="SCO6233"
                     /note="Pfam match to entry PF00356 lacI, Bacterial
                     regulatory proteins, lacI family, score 30.40, E-value
                     4.7e-07"
     PFAM_domain     23870..24007
                     /aSDomain="LacI"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00356.24"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory proteins, lacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6233_0735"
                     /evalue="1.00E-15"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO6233"
                     /locus_tag="SCO6233"
                     /protein_end="54"
                     /protein_start="8"
                     /score="57.4"
                     /tool="antismash"
                     /translation="TIKDVAAAAGVSKGAVSLAFNDKPGVSDATRERIFAVARQLGWAP
                     N"
     misc_feature    24035..24763
                     /gene_synonym="SC2H4.15"
                     /locus_tag="SCO6233"
                     /note="Pfam match to entry PF00532 Peripla_BP_like,
                     Periplasmic binding proteins and LacI family., score 44.00,
                     E-value 3.4e-09"
     PFAM_domain     24380..24856
                     /aSDomain="Peripla_BP_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13377.9"
                     /description="Periplasmic binding protein-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6233_0736"
                     /evalue="9.90E-34"
                     /label="SCO6233"
                     /locus_tag="SCO6233"
                     /protein_end="337"
                     /protein_start="178"
                     /score="117.1"
                     /tool="antismash"
                     /translation="VRYLAVLGHRRIAHVGGPRGLGHSAIRTTAFERTLSELGLDRGPH
                     VETGFSGEDGARATRSLLLSAERPTAILYDNDIMAVAGLGVAAEMGVSVPDDLSLLAWD
                     DSQLCRLTHPTLSAMSHDVHGFGAQVTRVLFDVLAGKDVTSRPVATPSLVPRAST"
     misc_feature    24913..26643
                     /note="92.1% match to SLBMANASE M92297 Streptomyces
                     lividans b-mannanase (manA) gene, partial cds, from 14 to
                     1708"
     misc_feature    24921..24934
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.67"
                     /tool="antismash"
     misc_feature    complement(24946..24961)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.33"
                     /tool="antismash"
     misc_feature    complement(24979..24994)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    complement(24980..24993)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.92"
                     /tool="antismash"
     misc_feature    complement(25081..25092)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     regulatory      25116..25121
                     /note="possible RBS upstream of manA"
                     /regulatory_class="ribosome_binding_site"
     gene            25126..26280
                     /db_xref="GeneID:1101675"
                     /gene_synonym="manA"
                     /locus_tag="SCO6234"
     CDS             25126..26280
                     /codon_start=1
                     /db_xref="GeneID:1101675"
                     /gene_synonym="manA"
                     /locus_tag="SCO6234"
                     /note="SC2H4.16, manA, probable beta-mannosidase, len: 384
                     aa; 94.5% identical to MANA_STRLI mannan
                     endo-1,4-beta-mannosidase precursor (363 aa). Contains
                     PS00659 Glycosyl hydrolases family 5 signature and Pfam
                     match to entry PF00150 cellulase, Cellulase (glycosyl
                     hydrolase family 5), score 104.70, E-value 1.8e-27"
                     /product="beta-mannosidase"
                     /protein_id="NP_630335.1"
                     /transl_table=11
                     /translation="MRKPRSTLITTAGMAFAAVLGLLFALAGPSAGRAEAAAGGIHVSN
                     GRVLEGNGSVFVMRGVNHAYTWYPDRTGSIADIAAKGANTVRVVLSSGGRWTKTSASEV
                     SALIGQCKANKVICVLEVHDTTGYGEDGAATSLDQAADYWVSVKSALEGQEDYVVVNIG
                     NEPFGNTNYTAWTDATKSAIGKLRGAGLDHALMVDAPNWGQDWSGTMRSNAASVFASDP
                     DRNTVFSVHMYGVYDTAAEVRDYLNAFVGSGLPIVVGEFGDQHSDGNPDEDAIMATAQS
                     LGVGYLGWSWSGNGGGVEYLDMVNGFDPNSLTSWGNRIFYGSNGIAATSRTATVYGGGG
                     GSTGGTAPNGYPYCVNGGASDPDGDGWGWENSRSCVVRGSAADH"
     misc_feature    25258..26031
                     /gene_synonym="manA"
                     /locus_tag="SCO6234"
                     /note="Pfam match to entry PF00150 cellulase, Cellulase
                     (glycosyl hydrolase family 5), score 104.70, E-value
                     1.8e-27"
     PFAM_domain     25279..26007
                     /aSDomain="Cellulase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00150.21"
                     /db_xref="GO:0004553"
                     /db_xref="GO:0071704"
                     /description="Cellulase (glycosyl hydrolase family 5)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6234_0737"
                     /evalue="7.60E-36"
                     /gene_ontologies="GO:0004553: hydrolase activity,
                     hydrolyzing O-glycosyl compounds"
                     /gene_ontologies="GO:0071704: organic substance metabolic
                     process"
                     /label="SCO6234"
                     /locus_tag="SCO6234"
                     /protein_end="294"
                     /protein_start="51"
                     /score="124.1"
                     /tool="antismash"
                     /translation="NGSVFVMRGVNHAYTWYPDRTGSIADIAAKGANTVRVVLSSGGRW
                     TKTSASEVSALIGQCKANKVICVLEVHDTTGYGEDGAATSLDQAADYWVSVKSALEGQE
                     DYVVVNIGNEPFGNTNYTAWTDATKSAIGKLRGAGLDHALMVDAPNWGQDWSGTMRSNA
                     ASVFASDPDRNTVFSVHMYGVYDTAAEVRDYLNAFVGSGLPIVVGEFGDQHSDGNPDED
                     AIMATAQSLGVGYLGWSWSGN"
     misc_feature    25597..25626
                     /gene_synonym="manA"
                     /locus_tag="SCO6234"
                     /note="PS00659 Glycosyl hydrolases family 5 signature"
     PFAM_domain     26161..26253
                     /aSDomain="CBM_10"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02013.19"
                     /description="Cellulose or protein binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6234_0738"
                     /evalue="1.20E-08"
                     /label="SCO6234"
                     /locus_tag="SCO6234"
                     /protein_end="376"
                     /protein_start="345"
                     /score="35.3"
                     /tool="antismash"
                     /translation="TAPNGYPYCVNGGASDPDGDGWGWENSRSCV"
     gene            complement(26344..26589)
                     /db_xref="GeneID:1101676"
                     /gene_synonym="SC2H4.17c"
                     /locus_tag="SCO6235"
     CDS             complement(26344..26589)
                     /codon_start=1
                     /db_xref="GeneID:1101676"
                     /gene_synonym="SC2H4.17c"
                     /locus_tag="SCO6235"
                     /note="SC2H4.17c, unknown, len: 81 aa; similar to S.
                     coelicolor TR:Q53896 (EMBL:X60316) abaA orfD (75 aa), fasta
                     scores; opt: 121 z-score: 174.5 E(): 0.018, 37.7% identity
                     in 53 aa overlap. Also similar to SC4G2.04 (E(): 4.6e-12,
                     54.5% identity in 55 aa overlap)"
                     /product="hypothetical protein"
                     /protein_id="NP_630336.1"
                     /transl_table=11
                     /translation="MNTTELAWFKSSYSSGGDGDRVEIALSWHKSSYSSSGDGDCVEVA
                     ARPDTIHIRDSKAPHGDQLAVSPTAWTRFLTYTTDR"
     PFAM_domain     complement(26359..26511)
                     /aSDomain="DUF397"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04149.15"
                     /description="Domain of unknown function (DUF397)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6235_0739"
                     /evalue="1.10E-21"
                     /label="SCO6235"
                     /locus_tag="SCO6235"
                     /protein_end="77"
                     /protein_start="26"
                     /score="76.7"
                     /tool="antismash"
                     /translation="SWHKSSYSSSGDGDCVEVAARPDTIHIRDSKAPHGDQLAVSPTAW
                     TRFLTY"
     gene            complement(26586..27461)
                     /db_xref="GeneID:1101677"
                     /gene_synonym="SC2H4.18c; SCAH10.01c"
                     /locus_tag="SCO6236"
     CDS             complement(26586..27461)
                     /codon_start=1
                     /db_xref="GeneID:1101677"
                     /gene_synonym="SC2H4.18c; SCAH10.01c"
                     /locus_tag="SCO6236"
                     /note="SCAH10.01c, possible DNA-binding protein, len: >270
                     aa; similar to TR:Q9Z543 (EMBL:AL035212) Streptomyces
                     coelicolor binding protein, SC9B2.16c, len: 303 aa; fasta
                     scores: opt: 466 z-score: 574.2 E(): 1.3e-24; 34.1%
                     identity in 252 aa overlap. Contains a possible
                     helix-turn-helix motif between residues 612..677 (+3.39
                     SD); SC2H4.18c, unknown, partial CDS, len: >55 aa; some
                     similarity to the C-terminus of S. coelicolor hypothetical
                     protein SC4G2.03, fasta scores; (E(): 0.018, 32.7% identity
                     in 52 aa overlap)"
                     /product="DNA-binding protein"
                     /protein_id="NP_733694.1"
                     /transl_table=11
                     /translation="MGPLSGRDGWEVSRMTDGTGGAGEPEASDSLKAFGEVVKAFRKRA
                     GLTQEEFAPQVRYSVPTVASIEQGRRFPPVDFVERAEAALDAFGALRGAARHLSRQPGL
                     ASWFRQWARFEAEAVSLYTYECRLIPGLLQTEAYARTLFTNQLPPLGDDQIEAQWVARA
                     ERQRLLRELPNTAFSFILEEHLFLRRMGGTQVTRELIDHVLGLAELRNVEVQVMPLVRN
                     AHAGMAGPMQLLETPEARWFAYNEGQRGGLFVSERKEVSVLQMRYARMRSQALSLDDSL
                     GLLRRMRGAS"
     regulatory      complement(26594..26598)
                     /gene_synonym="SC2H4.18c; SCAH10.01c"
                     /locus_tag="SCO6236"
                     /note="possible RBS upstream of SC2H4.18c"
                     /regulatory_class="ribosome_binding_site"
     PFAM_domain     complement(26604..27140)
                     /aSDomain="DUF5753"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19054.3"
                     /description="Domain of unknown function (DUF5753)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6236_0741"
                     /evalue="3.00E-43"
                     /label="SCO6236"
                     /locus_tag="SCO6236"
                     /protein_end="286"
                     /protein_start="107"
                     /score="147.7"
                     /tool="antismash"
                     /translation="FRQWARFEAEAVSLYTYECRLIPGLLQTEAYARTLFTNQLPPLGD
                     DQIEAQWVARAERQRLLRELPNTAFSFILEEHLFLRRMGGTQVTRELIDHVLGLAELRN
                     VEVQVMPLVRNAHAGMAGPMQLLETPEARWFAYNEGQRGGLFVSERKEVSVLQMRYARM
                     RSQALSLDDSLGLLRR"
     PFAM_domain     complement(27186..27365)
                     /aSDomain="HTH_31"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13560.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6236_0740"
                     /evalue="1.60E-12"
                     /label="SCO6236"
                     /locus_tag="SCO6236"
                     /protein_end="92"
                     /protein_start="32"
                     /score="47.7"
                     /tool="antismash"
                     /translation="AFGEVVKAFRKRAGLTQEEFAPQVRYSVPTVASIEQGRRFPPVDF
                     VERAEAALDAFGALR"
     gene            27568..28050
                     /db_xref="GeneID:1101678"
                     /gene_synonym="SCAH10.02"
                     /locus_tag="SCO6237"
     CDS             27568..28050
                     /codon_start=1
                     /db_xref="GeneID:1101678"
                     /gene_synonym="SCAH10.02"
                     /locus_tag="SCO6237"
                     /note="SCAH10.02, possible regulatory protein, len: 160 aa;
                     similar to TR:Q53897 (EMBL:X60316) Streptomyces coelicolor
                     A3(2) ORFA in AbaA gene, len: 192 aa; fasta scores: opt:
                     245 z-score: 318.1 E(): 2.4e-10; 36.5% identity in 148 aa
                     overlap and to TR:O86675 (EMBL:SC4G2) Streptomyces
                     coelicolor SC4G2.02c, 196 aa; fasta scores: opt: 436
                     z-score: 440.2 E(): 3.4e-19; 51.4% identity in 138 aa
                     overlap"
                     /product="regulatory protein"
                     /protein_id="NP_630337.1"
                     /transl_table=11
                     /translation="MRPASTPRLPVTARVFVQRFSSTPRGARLARHLVVHRLDAWGVPY
                     GSALSDTAALLVAELAANAVTHGRVPGRDIEVLLRLDAYTLRIDVSDSRGERRPMVTAV
                     TAAPEAEHGRGLLLVDALADRWGVFDRVPVGKTVRAELDLPPRDQRSRTADDFARE"
     PFAM_domain     27625..27984
                     /aSDomain="HATPase_c_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13581.9"
                     /description="Histidine kinase-like ATPase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6237_0742"
                     /evalue="4.50E-10"
                     /label="SCO6237"
                     /locus_tag="SCO6237"
                     /protein_end="139"
                     /protein_start="19"
                     /score="39.7"
                     /tool="antismash"
                     /translation="FSSTPRGARLARHLVVHRLDAWGVPYGSALSDTAALLVAELAANA
                     VTHGRVPGRDIEVLLRLDAYTLRIDVSDSRGERRPMVTAVTAAPEAEHGRGLLLVDALA
                     DRWGVFDRVPVGKTVR"
     gene            28103..28768
                     /db_xref="GeneID:1101679"
                     /gene_synonym="SCAH10.03"
                     /locus_tag="SCO6238"
     CDS             28103..28768
                     /codon_start=1
                     /db_xref="GeneID:1101679"
                     /gene_synonym="SCAH10.03"
                     /locus_tag="SCO6238"
                     /note="SCAH10.03, hypothetical protein, len: 221 aa;
                     similar to various hypothetical proteins, e.g. TR:O53480
                     (EMBL:AL021899) Mycobacterium tuberculosis hypothetical
                     23.2 kD protein, 213 aa; fasta scores: opt: 381 z-score:
                     468.2 E(): 1e-18; 38.3% identity in 201 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_630338.1"
                     /transl_table=11
                     /translation="MTDPELTAERGQGTGVWPLIRTERAALAADLAELTGEQWATPSLC
                     AGLTVREVLAHLTAGASLNTVRWFAGVIRCRFDFDKQVAVRLAEQLGADPAETLARFRR
                     VVPSTTKPPLPAIAMLGETLVHGEDIRRPLGIRHDYPVGVVTRVAEYYRGSDLVVVAKK
                     RIEGLRLAADDGPFTTGSGPVVSGPTMALVMAMTGRETYCDDLEGDGVELLRDRCRTP"
     aSDomain        28160..28699
                     /aSDomain="TIGR03083"
                     /aSTool="tigrfam"
                     /description="TIGR03083: uncharacterized Actinobacterial
                     protein TIGR03083"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6238_0093"
                     /evalue="3.10E-34"
                     /identifier="TIGR03083"
                     /label="SCO6238"
                     /locus_tag="SCO6238"
                     /protein_end="199"
                     /protein_start="19"
                     /score="117.0"
                     /tool="antismash"
                     /translation="IRTERAALAADLAELTGEQWATPSLCAGLTVREVLAHLTAGASLN
                     TVRWFAGVIRCRFDFDKQVAVRLAEQLGADPAETLARFRRVVPSTTKPPLPAIAMLGET
                     LVHGEDIRRPLGIRHDYPVGVVTRVAEYYRGSDLVVVAKKRIEGLRLAADDGPFTTGSG
                     PVVSGPTMALVMAMTGR"
     PFAM_domain     28163..28429
                     /aSDomain="MDMPI_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF11716.11"
                     /db_xref="GO:0046872"
                     /description="Mycothiol maleylpyruvate isomerase N-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6238_0743"
                     /evalue="8.00E-10"
                     /gene_ontologies="GO:0046872: metal ion binding"
                     /label="SCO6238"
                     /locus_tag="SCO6238"
                     /protein_end="109"
                     /protein_start="20"
                     /score="39.7"
                     /tool="antismash"
                     /translation="RTERAALAADLAELTGEQWATPSLCAGLTVREVLAHLTAGASLNT
                     VRWFAGVIRCRFDFDKQVAVRLAEQLGADPAETLARFRRVVPST"
     misc_feature    28864..30907
                     /note="region of very low C+G content (62.91%)"
     gene            complement(28993..29961)
                     /db_xref="GeneID:1101680"
                     /gene_synonym="SCAH10.04c"
                     /locus_tag="SCO6239"
     CDS             complement(28993..29961)
                     /codon_start=1
                     /db_xref="GeneID:1101680"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /gene_synonym="SCAH10.04c"
                     /locus_tag="SCO6239"
                     /note="SCAH10.04c, possible sigma factor, len: 322 aa;
                     similar to TR:CAB42013 (EMBL:AL049754) Streptomyces
                     coelicolor sigma factor, SCH10.04c, 294 aa; fasta scores:
                     opt: 379 z-score: 438.7 E(): 4.6e-17; 34.7% identity in 291
                     aa overlap and to (EMBL:AL132707) Streptomyces coelicolor
                     SCF51.13c, 298 aa; fasta scores: opt: 833 z-score: 802.7
                     E(): 0; 44.9% identity in 305 aa overlap"
                     /product="sigma factor"
                     /protein_id="NP_630339.1"
                     /transl_table=11
                     /translation="MPEDTPAESAEFGGAEGDESTALDSVMAERHRLLSLAFRMMGTLA
                     DAEDVVQETYVRWYRLEPEERDSIAVPAAWLMRVASRISLDLLGSARARREMYVGQWLP
                     EPVPADLFADTAKAPLNSGSSAADPLDRVTLDDAVSMALLTVLEAMTPAERVTFVLHDV
                     FGVPFGEIAGVVGRSAAATRQLATSARRHVRRGRRARVSPHQHDEVVRAFRDATVGGDI
                     EDLLRVLAPDVELRVDGGGFVNAAPKVIHGSNHVARWFQGVMRKQPGLRLERRETADGL
                     GYILRDEERRYGMVTFDVSGECVTNVWLMLNPMKLTNWPLD"
     PFAM_domain     complement(29386..29541)
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08281.15"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006352"
                     /db_xref="GO:0006355"
                     /db_xref="GO:0016987"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6239_0745"
                     /evalue="4.60E-06"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006352: DNA-templated transcription
                     initiation"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /gene_ontologies="GO:0016987: sigma factor activity"
                     /label="SCO6239"
                     /locus_tag="SCO6239"
                     /protein_end="192"
                     /protein_start="140"
                     /score="26.3"
                     /tool="antismash"
                     /translation="MALLTVLEAMTPAERVTFVLHDVFGVPFGEIAGVVGRSAAATRQL
                     ATSARRH"
     PFAM_domain     complement(29689..29880)
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04542.17"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006352"
                     /db_xref="GO:0006355"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6239_0744"
                     /evalue="2.60E-11"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006352: DNA-templated transcription
                     initiation"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO6239"
                     /locus_tag="SCO6239"
                     /protein_end="91"
                     /protein_start="27"
                     /score="43.2"
                     /tool="antismash"
                     /translation="AERHRLLSLAFRMMGTLADAEDVVQETYVRWYRLEPEERDSIAVP
                     AAWLMRVASRISLDLLGSA"
     gene            complement(30044..30778)
                     /db_xref="GeneID:1101681"
                     /gene_synonym="SCAH10.05c"
                     /locus_tag="SCO6240"
     CDS             complement(30044..30778)
                     /codon_start=1
                     /db_xref="GeneID:1101681"
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /gene_synonym="SCAH10.05c"
                     /locus_tag="SCO6240"
                     /note="SCAH10.05c, hypothetical protein, len: 244 aa;
                     similar to various hypothetical proteins, e.g. TR:CAB52958
                     (EMBL:AL109950) Streptomyces coelicolor hypothetical 25.2
                     KD protein SCJ4.24c, len: 242 aa; fasta scores: opt: 504
                     z-score: 580.0 E(): 6.2e-25; 36.9% identity in 241 aa
                     overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_630340.1"
                     /transl_table=11
                     /translation="MKVFIAGGRGRVGSLLADNLEAKGIEVVSGGLEDGIDVISGKGLT
                     EALAGVDTIVNVLNTPRFDAEGAISFFEGAINNLTAEGERAGVRHHIVLSIVGVGQGDA
                     SEVGYYLGKVAQEKAVRSASIPATIIRATQFQSYIPVLIDQHTVDGKVIAPRSFVQPVE
                     LDEVIELLAEAATTLEPGSEVEIAGPDRFYHDDLFRATLADRGDDREVVTVDAEGAPDV
                     MVPRGAYRTGTVRYPITGIPTV"
     PFAM_domain     complement(30341..30733)
                     /aSDomain="NmrA"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05368.16"
                     /description="NmrA-like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6240_0746"
                     /evalue="2.50E-05"
                     /label="SCO6240"
                     /locus_tag="SCO6240"
                     /protein_end="146"
                     /protein_start="15"
                     /score="24.0"
                     /tool="antismash"
                     /translation="LADNLEAKGIEVVSGGLEDGIDVISGKGLTEALAGVDTIVNVLNT
                     PRFDAEGAISFFEGAINNLTAEGERAGVRHHIVLSIVGVGQGDASEVGYYLGKVAQEKA
                     VRSASIPATIIRATQFQSYIPVLIDQH"
     regulatory      complement(30787..30790)
                     /regulatory_class="ribosome_binding_site"
ORIGIN
        1 tcgccggcaa gtacgtcctc gacgccacct tccgcgccta cgagacgtgg tcgttcagct
       61 gctccgccaa gtgggtggac ctggagcgca ccaacaacat ctcggagggc acccggtggc
      121 ccggcccgac ccagctggac cagatgggcg accggtacgt ctccgccgga cgcggcagcc
      181 agtgcagccc ggaccagccc gaccagtgga tcgagttcaa cgacaacccg gacgagaccg
      241 acgagaacct cgcctccacg gtgcgcaagt tcgccgacgg caagatcagc cggctcacgc
      301 tgatgctgcg cgccaaggac gagtccgacc ccgaggcgtg gaagcggttc gacgacaacg
      361 ccgaactgaa ggtgacctac gccttcaagc ccggcgtgcc caccagcgtc ggcgtcatcc
      421 cgggcgacgg caccaccgcc tactgccgta cctcctcctc cgacccgctg atcgtcaccc
      481 ggatcgaccc catggtgcag tcccgggtgc agacccaggt cgagcaccac ctgggtgacg
      541 aggagggctc cctccaggcc gagttcgtcg tcgagcgcgg cgacgacgcg gcctggcacc
      601 aggtgtggtc cggctaccgg ccctcctccg gctgggaccc ggacgagaca ctggagaaga
      661 tgcgcacctc caaccgggcc gacggcggtc tgtaccggct gcgctcacgc acccagtccc
      721 actggtcgta cagcggcaag tccggcgacc tgttctcctc gtactcctcg tggtgctact
      781 tcaagatcga ctcgacggcc cccaaggccc cggtcatcac ctcgctctcg ccctacaccc
      841 agtgcaccgc cgacctgtgc gagggcaagg gcggtccggg gacggccggt tccttcacct
      901 tccagcccaa cgccgccgac accgacatca ccggctaccg ctggcggctg ctgaccacct
      961 cggccaagga ggccaaggcg gtcaccggca agtcggtcac cgtctccgac gtgacaccgt
     1021 cgctgtcggg tacgcaggtg ctgtccgtgg aggccaagga cgtccgcagc cgctggggag
     1081 ccccggcgga gttcagcttc aaggtcgccc ccgcggccgg cgccacgggc acctggcact
     1141 tcgacgacgc cctgcccgga tcgggtgtga cgatcgccaa ggacaccgcc gccgagggca
     1201 cccggcacga cgccaccctc tacaccgcgg gcgccggctg gtccacgctg gcccggcgcg
     1261 gcgacgccga caactcgctg tggctcaacg acggttcgga cacgacgcag cgggccggct
     1321 acgccgcgac atcggccccg gccgtgaaca cgagggactc cttcaccgtc tcggcgtggg
     1381 cctatctgac cgacacctcc cagacccggg tggtgatggc ggcccccggc acctacggtt
     1441 cggcgttcac gctgtactac tcggcctcgt acaagaagtg ggtcttcaac cggaccgccg
     1501 gcgacgtcaa ggacaagccg gtctacctcc ggtcgctcgg tgacgccacc gccccgccgt
     1561 tgaaggtgtg gacccacctg gccgcggtgt tcgacacgaa gaaggacacg aacaaggcga
     1621 acgacaccat ccagctgttc gtcaacgggc gcccgcaggg tgaacccgtc gtactcgacg
     1681 gcgtgtcgac cgcctatcag ccgtgggtct cctccggcgg gctgcagatc ggccgctccc
     1741 tggtcggcgg tgcctggggc gagcacttcc gcggccgcct cgacgaggtg aacgtgtggc
     1801 agcgcgtgct gactccggac gagatcaccc agcaggcgca actcctcgag gagggcgtgc
     1861 cggccaacga gctcgtcgcg cagtgggacg ccgcgtcgtc caccggcacc acggtcaagg
     1921 agctctcctc ctaccccgcc ccgagcctga cgctgtcggc cgccggggcg gtgctggacg
     1981 aggagaacaa cgccctcgtc ctggacggat cggcgggcta cgcctccgcg accggcccgg
     2041 tcgtcgacga gacgggctcc ttcacggtct ccgcccgcgt ccagttggac tcggccaagc
     2101 tcgcctcgaa gccggtcggt tatgaggccc tggtggccgg gcagcaggca agcgccggtg
     2161 agtcctcctg ggcactgtgg gcggtgaagc ccgccgacgg cgtctaccag tggaagttca
     2221 cccgcaccgc cgtcggcgcc gacggcaagg tgacccagtc cgccgaggcg ccgggcggcg
     2281 acatcgccga gaccgacacc tgggtgcagg tcaccggcgt cttcgacgcc caggagccct
     2341 gggagtggac ggacccggcc gactcggcga agacggagac ccgctacggc agactccacc
     2401 tctacgtcgg cgagttcgac cagccgtcgg agaccgcgtc cgggttcacc accccccagt
     2461 acggcgccgg tgccctggcc gtgggccgcg gcagccgggg cggcaccacc gggcaccacc
     2521 tgcccggcgc cctggaggaa ctgcgggtgt ggaccggcgc gatgagcgcc gaccaggtcc
     2581 ggtcgcaggt cctcggcggc gtctgaacga cgccctcccc ccctctgaac cggtccgggg
     2641 cgcggtcacc cgtgccccgg accggcccgc tgcgtccgtc gtggaccggc gtccgccttg
     2701 gcgccgcgtc ccttcgacgt gccttctcgg acaaggaatc ccatgagaca ccaccccctg
     2761 ggggtccccg gcgcggggac cggaccaggc ccccaccggc gccgggcggt acgcccctgg
     2821 atgcgccgtg tgagcgcggt cgtcggcatc gccctgctgc ccggcctgct cgcccccgcc
     2881 gccaccgccg acgacgtgga cccgctcggc cggcccgagc tgtccacgcc gcgcgcccag
     2941 cacgtggcgc cgttcaaggc gaggccggac gcccggaccg cggccgtcgt acgcgactcc
     3001 gcccgcgccg accagtcggc ggccggccgt gccgtcaagg accggtcccg cggcaccagt
     3061 tggcccaccg ccggctcggc ccggctgacc gcgtccgggg gcgcggccga cgaggccgcc
     3121 cccggtcggc tgcccgtcac ccttgccccg ccggcggcga agaaggccaa gcgcgccgac
     3181 cgcgtcaagg tcgatgtcct cgaccagaag gccgcccgcc gcctcggcgt caagggcgtc
     3241 gtcctgaagg tcaccggccc cgccgacggc ggcgcggccc gcctcggcat cgactactcg
     3301 gcgttcgccg ccgcctacgg cggcgactgg gccggccgcc tccaggtgct gcgcctgccc
     3361 gactgcacca ccgcctgccc gcccgcgacg ccggtgaagt tcaccaacga gcggggcgac
     3421 gagcggctca ccgccgatct cgccttcgcc ccgaaggcgg cttccgggca gaccatgact
     3481 ctcgccctgg cggccggcac cgcctccgcc gacggcgact acaaggcgac accgctcgcg
     3541 ccgtcctcga cctgggaagc cggcggcagc tccggctcgt tcacctggtc ctacccgctg
     3601 aaggcgcccg agccggccgc cggcgaggcc ccgaagctgg agatctccta cgactccggc
     3661 agcgtcgacg gccgcacctc caccagcaac aaccagggca ccgaggtcgg cgagggcttc
     3721 gacatcacct cgtccttcat cgagcgcaag tacggctcgt gcaccgacga cgggcacgcg
     3781 gaccggcacg acctgtgctg gaagtacgac aacgcctccc tggtcctcaa cggcaaggcc
     3841 accgagctgg tcaaggacga caccaccggg cagtggcggc tgaagaacga cgacgcctcc
     3901 aaggtcaccc actccaccgg cgcggacaac ggcgacgaca acggcgagta ctggaccgtc
     3961 accacgggcg acggcacccg cttcgtgttc ggacagaaca agctcgacgg cgccgccgcc
     4021 gacgtccgca ccaagtcggt gtggaccgtg ccggtcttcg gcgacgacga gggcgagccc
     4081 ggttacgccg acggaaccgg cttcacctcg cgcgacgaga agcaggcgtg gcggtggaac
     4141 ctcgactacg ccgaggacac ccacggcaac gccacgacct actggtacga ggacgagacc
     4201 aacaactacg acaagctcgg tgacgacgac accggcacgt cgtacgtccg cggcggctac
     4261 ctcaaggaga tccgctacgg acagcgggcc ggcgccctct tctccggcac accccaggcc
     4321 tcgcacagaa tcgtcctcgg ccacgacgag cgctgcctgg cctccggcac cggctgcgac
     4381 gcgctcaccg aggacacccg ggacaactgg cccgacgtgc ccttcgaccg gatctgcaag
     4441 gacggcgaca agtgcccgta cctggacagc ccgtcgttct tcacccgcaa gatgctgacc
     4501 tcggtcagca cctacgcgtg ggacgccgcg gcggccaccc ccgccttctc gccggtcgac
     4561 acctggaccc tcgagcacct ctacctcgac ccgggcgaca ccggtgactc caccgaccag
     4621 tcgctgtggc tggacgagat caagcacacc ggcaagcggg ggaccgacct ctccctggac
     4681 gcggtgaagt tctcccacgt cttcatgccg aaccgggtgg acggccccag cgacgacatc
     4741 ctctccttcg agcggccccg cctgcggacc gtcgtctccg agaccggggc gcagacgatc
     4801 gtcgactacc tgcccgcgga ctgcgtggcc gggcagacca tgcccaaggc ggacgagaac
     4861 accaagcgct gcttcccggt gtactggtcg ccctacggcc aggaggagcc gatcctcgac
     4921 tggttccaga agtaccccgt cagctccgtg cgcaccaccg acccgctggg cggctccgag
     4981 gccgtgcagc acacctacga gtactccggc ggcggagcct ggcactacaa cgacgacccg
     5041 ctgacccccg ccaaggaacg cacctggtcc cagtggcgcg gctacggcaa ggtcacccac
     5101 tacaccgggc cgtccggcgg cacccgggcc aagaccgtca ccgtgtacct gcgcggcatg
     5161 gacggtgacc gggtcctcgg cggcgacggc aagacgcccg acccggaccg gcgccggaag
     5221 gcggaggtct ccggcgtcac cgccgcggcc gtcaccgact ccgaccagct ggccggcttc
     5281 cagcgcgaga gcgtcgcgta cgacggcgac aaggaggtgt ccggcaccgt caacgacccc
     5341 tggtccaagc ggacggcgac ccagcacaag tcgtacgccg acaccgaggc gtactacgtg
     5401 cgtgtgggcg cctcgcacgc ccgcacccgc atcaccagcc ggctcaaccc ctacgaccgg
     5461 gtgcgcacca ccaggacggg ctacgacgac tacggcatgc ccgtgtcggt ggaggacctc
     5521 ggcgacgact ccgtcacggg tgacgagaag tgcacccgca cctggtacgc gcgcaacgac
     5581 gccgcggggc tgaccgcgct ggtctcccgg acccgcatcg tcggccgggc ctgctcggtc
     5641 accgactccg ccctcgacct gccggcggac gccgcacgcc ccggcgacgt cgtctccgac
     5701 aaggccaccg cctacgacac gaccacctgg tcggcgacgc agaagccgac caagggcgac
     5761 gcccgctggt ccggccgcgc caagggctac ggcggcgacg accgcccgct gtggcagacg
     5821 acggccgtca ccgactacga cacgctgggc cgcccggtcc aggtgaggaa caccgacgac
     5881 gtcatcacct ccaagaccga gtaccagccg cccgcggccg gtccgctgac ctcgaccacg
     5941 gtcgtcaacg ccaaggggca ccggaccacc acggtcaagg acttcgcgct gggcgcggac
     6001 ctgaaggtca ccgacgccaa cgggaaggtg accgagtccg cctacgacag cctgggccgc
     6061 gtcacctccg tgtggctgcc gaaccgctcc cgcgcgctcg gcaagaccgc caactacgtc
     6121 tacggctaca gcgtcaagtc cacgtccctg ccgtgggtct ccagcgccac cctgaacggc
     6181 gacggctccg gctaccgcac cacctacgag atctacgact cgctgctgcg cacccgacag
     6241 gtgcaggcgc cctcggcgca gggcggccgg gtcatcgcac agaccctcta cgacggtcgt
     6301 ggcctgccgg tcaccgcaca ggcggacatc tgggacgaca ccgcggcccc ggccggcaag
     6361 atcgtgcaga tcgacggcgg ccaggcgccc cggcagaccg acagcgtcta cgacggcatg
     6421 ggccgcgtca ccaaggcggt caccaagagc tacggcgtga ccgagtgggc cgtcgacacc
     6481 gcctaccggg gcgacctggt cctcaccggc gccccggagg gcggctcggc caacgcggtg
     6541 gtcaccgacg cgttcggacg gaccgtcgag cgccgtgact acgcgggcac ccagccggcc
     6601 ggcacggact acatgaccac ccggtacgcc ttcgacgccg ccgaccggca gaagtcgatc
     6661 accgcgcacg accggtccgc gtggacctac acgtacgacc tcttcggccg ccaggtgtcc
     6721 gtcaccgacc ccgacaaggg cacgacggtc accgagtacg acgcgctcga ccgggcggtg
     6781 aagtccaccg acggccgcgg cgaggtgctg ctgttcgagt acgacgtgct cggccgcaag
     6841 acgggcatgt ggcagtcggc caagaccggc gcgaacaagc tggcggcctg gtccttcgac
     6901 accctcgcca agggccagca ggacacggcc gtgcgctacg agggcggcga gaccggcagg
     6961 gcctacaccc agaaggtcac ccgctacgac cccctgtaca aggtcaccaa caacgaactc
     7021 accctccccg cgaacgaccc cctggtcgcg gccggcgtgc ccgccaggct ggccttctcc
     7081 acgggctaca acctcgacgg caccgtcaag caggcggccg cgcccgcggt ggccggcctg
     7141 tccgccgaga ccgtgtccta cacctacgac gggctcggcc aggtcctgac cgccaagggc
     7201 accaccggct acctccagca ggcggcctac tcgccgctgg gcgacctgcg ccagatgacg
     7261 ctcgccaccg acccgaccgg ggcgaagaag gtctacctca acaacgacta cgaggccggc
     7321 acccgccgcc tcacccggtc gtacgtcacc gacgacgtcc acggcttcat gctccaggag
     7381 ctgaagtacc agcaggacga cgccggcaac atcacctccg tctccgacgc caccacgctg
     7441 ggcggcaccg gcaaggcgga ccaccagtgc ttcacctacg acggccaccg ccggctgagc
     7501 gaggcctgga cgcccgagac cgccgactgc tccacgtccg gccgcaccgt cgcgggcctc
     7561 ggcggggcgg cgccgtactg gaccagctac cagtacgacg actccgggct gcgctcgaag
     7621 cagaccgagc accgcatgtc gggcgacgac gtcaccaccg agtacgagta cggcacggct
     7681 gagggtcagc cgcacgccct gtccgccacg gtgaccggcg ccgagaacgc gtcgtacacc
     7741 tatgacgaga ccggcaacac cgagacccgg cccggggtcc gggccaccca gaccttggac
     7801 tggaacgccg agggcagact cgccggcgtg agcgagcccg ccgcgggcgg caagccggcc
     7861 accggcaccg cctacgtcta cgacgccggt ggcgacctgc tcatccgccg ccccaccacc
     7921 acggacggcg agaccgtgct gtacctgggc accaccgagg tccacctcaa ggtgagcggc
     7981 aacggcgcgg ccaaggcgct gtccggcgcc cgcacctaca aggcgggctc ggccgtcatc
     8041 gccgtccgca cctccaccgc gggcgtctcc ggcacgaagc tcaccttcct tgccggcgac
     8101 caccacggca cctcggggct ggcgatcaac gccgacacgc tggccttcgc caagcgctgg
     8161 tcgacgccgt tcggtgctcc gcgcggcacg gcctccggcg cctggcccga cgacaggggc
     8221 ttcctgggca agccggccga cgccgcgacc ggcctcaccc agctcggcgc ccgccagtac
     8281 gacccggaca ccgggcggtt cctgagcgtc gacccgctgc tcgaaccgga caagccgaac
     8341 actctcaacg gctacgccta cgccagcaac agcccggtca ccaactccga cccgagcggc
     8401 accagtgacg gtctcggcgg tctcctcggt gccatcgggg cgatcatcgg cggtgtcgtg
     8461 ggcgcggtga tcggcgcggt cggtgccgcg atcacggccg tcggctcgct cggcggtggt
     8521 ggcggcggtg gctggggcgg cacggcgccc acctcgtccg gtggctggac acagccgctg
     8581 accaagcagt ggacgccggg ggcgacctac aacttcatca ccaagtcgtg ggacctgccc
     8641 ttcaacccgc cctcccagag cctggaggag atgctggcgt cgatgcccga ctggggcata
     8701 gtcagcgacc ccaaggccgc caaccgctgg gagacctcgc gctccctgtt cttcggctgg
     8761 ctgtggggcg gtggctaccc gctgcgcgag caccaggact tccgcggagg cgacgccttc
     8821 acgtccatcc tggcgcagga cgagaccatc tccggcctgc ggtcgaagat ggtcggccaa
     8881 gcccgcaagg gcacgaaggg cgccttcgcc aaggaggtcg gcttccagta cgtggacgag
     8941 ggtcccgagc ccggcagccc ctggtacaag ttcaactcgc tgcgcggtgc ggcgaaggac
     9001 atcgccggtg tgctgactaa cggcgccgtg ggcaccggca accaggccga cgccttcctg
     9061 ggcacgtaca gcggcaaggc caggatcagc tcgatcaaca agaaggaggg ttcggtcacg
     9121 ctcaagttca gcgcctggaa cggctccgac tggcggtccg cgacccacgt cgttccccgt
     9181 tcgtggaacc ccgcgttcga ggacaccttc ggggcggcgg tccgggagga cttctcgtgg
     9241 gaggagaagt ggcccatcaa cgagtgcgtg aactactcgg agtggctgga gtagcactac
     9301 cgcgtccgtg acagacgccc ggtggtccgg ggcggcccgc cgccccggac caccgccgta
     9361 tcctgcaccc ttctaggatt cctccgtgct caagacaccc ttcgcgcccg ccgtccgctg
     9421 gacggccgcc gtgctgatca ccctgttggc ggccacggcg tgcgacgaca ccggcgcgcg
     9481 ggccgcgacg gtccccgccg accgcgtcac cggcgcctgg caggccggcg gcggcacggc
     9541 cctcaccctg tccgccgacc gcaccttcac tgcgtccggg ctcgactcgg gcaagcttgc
     9601 cggcaccggc tgccccggtg gggacaccgg cggcgactgg gccttcttcg ccgacgacgg
     9661 cgacggcctg tacatgacct cgccgcgggc ccggtcggga tcggagatcg gcctgtcctt
     9721 cgccgagcag tccgacgagc cctgccggct cacgctgacg gtcgtcgacg acggcgacac
     9781 cctgtgcgcc acgtcggacc cggagacccc ctgcgacctg ggcgtccgct tcacccggaa
     9841 ggactgaggc ccggccgcta ctgccggtac ccgctcagga agcgcccgat gcgtccgatc
     9901 gcggcctcca ggtcctccgc gtgcggcagg gtcaggatgc ggaagtggtc gggggagggc
     9961 cagttgaagc ccgtcccctg caccacctgg atcttctccc gcagcagcag gtccaggacg
    10021 aagcgctcgt cgtcgtggat cttgtggacg gccgggtcga tgcgcgggaa ggcgtacagc
    10081 gcgcccttgg gcttgacgca ggagatgccg gggatctcgt tgagcttctc ccaggcgacg
    10141 tcccgctgct cgtgcagccg tccgccgggg gccgtcagct cgcggatgga ctggcggccg
    10201 ccgagcgcgg cctggatggc gtactgggcg ggcgcgttgg cgcacaggcg catggaggcc
    10261 agcatggtca ggccctccag gtagtccctc gcgtgctgct tcggccccgt caccaccagc
    10321 cagccggagc ggaaacccgc cacccggtac gtcttggaca ggccgcagaa ggtcagcacc
    10381 accaggtcgg gggcgaggga cgcggccgag tggtgcacgg cgtcgtcgta caggatctgg
    10441 tcgtagatct cgtcggcgag gaccatcagg ccgtgccggc gggcgaggtc gaggatgccc
    10501 tcgacgatct ccttggggta gacggcgccg gtggggttgt tggggttgat gatgacgacc
    10561 gccttggtgc ggtcggtgat cttcgcctcc atgtcggcca ggtcggggta ccactcggcc
    10621 tgctcgtcgc agaggtagtg caccgccttg ccgcccgcga gggtggtcac cgccgtccag
    10681 agggggaagt cgggggcggg gatcagcacc tcgtcgccgt cctcaaggag ggcctgcacg
    10741 gccatggaga tcagctccga gacgccgttg cccaggaaga cgtcgtccac gtccacctcc
    10801 aggccgagcg cctggtagcg ctgggcgacg gcccggcggg cggagaggat gccgcgcgag
    10861 tccgtgtagc cgtgcgccct cggcagcatg cggatcatgt cctggacgat ctcctcgggc
    10921 gcctcgaacc cgaagagggc ggggttgccg gtgttcaggc gcagcacgct gtgccccgcc
    10981 tcctccagcg cgttggcgtg ctcgatgacc gggccgcgga tctcgtaaca gacctcgctg
    11041 agcttgttcg actgccggaa ctccatgcgc ggcttcccct ccggaatctg gtgttgcttg
    11101 gttttaccaa gtagtcgctt ggaaagtcca acaacttgtc tacactgcgt cgcatgtcac
    11161 ctcgccgtag ctacgaccag tactgttccg ccgcccgcgc gctcgacgcc gtcggcgacc
    11221 gctggaccct gctgatcgtc cgggagctgc tcgccgggcc gcggcgctac accgacctgc
    11281 acgccgacct gcccggcgtc agcacggacg tactcgcctc gcggctcaag gacatggagc
    11341 gcgaggggct gacgaccagg cgccggctgc ccccgccggg tgcggcgtac gtctacgaac
    11401 tcaccgcacg gggacgcggc ctgctgcccg tcctggaggc gctcggcgca tggggcgcgg
    11461 gcgagttggg ggagcggcgg ccgaccgacg ccgtacgcgc gcactggttc gccctgcccc
    11521 tgctgcgggc cctgcgggag gccggggcgg gggaggggct ggtcgaagtc cggctggagg
    11581 agggggactt ccatctgtac gccgacgccc gcgccgaggg ggaggacggt cccgtgtacg
    11641 gcgaggggcc cgcaccgggc gagcccgacg cccggctcgt gctggacgcc gtgacgtgcg
    11701 cggccctcgg ccgcggtgag acgggtctgc gggaggcggt gcgggacggc cgggtccagg
    11761 tgaccggcga cggcacggtg gccaaggcgc tgcgggaggg gtgaacagga ggggacaacg
    11821 acaggaggcc cgccggagcg ggcctcctga ggacgcgtca ggcgcccggc ggcacccggg
    11881 tcggacgtcc cgaaccacgg gtcagcgcgt aaccgccgat gccggcgagg gcggccagga
    11941 cggccccgat cccgctccac acccagcggt ccgaccacca gcccgacgac cagccgtcct
    12001 ccggctcgat cgcggacagc acggcgccgc ggtcgtcctc gtcgtcctcg gaagcgctgc
    12061 cggtgcccga cgtcaccgcg atgcccggca ccagcggctc ggccagcgaa ccgtccaccg
    12121 ccgcggcccc gccgatgtcc ttggagtccg cccgcacctc ggcggagacc ggtacaccga
    12181 ggtcggaggt gggcacgttc accgccgtga gccggacgta ataggtgccc gggagagggt
    12241 cgttggccca cggctcggtc caggcgcgca cggtgcgcag gacgcaggcc agctcgacgg
    12301 aggaggtgcc cgcgtccgcg gtgcgggcct gcgcgcccca ctggcaggcc tggcggcggc
    12361 gcaggccgtc gtacacgtcg acccgccagg tctgggcggc gtgcgtctcg ggcagcttca
    12421 ccgtggcctt gacggtgggc cgctgcccgg cgtcggccgg gaacgaccag tacaggtagt
    12481 cgcccgcggc cccgctcgcc gtggccgcct gtccctgctc gaactcggtc gccgtacgga
    12541 aggacgtgcc cgccgtggtc ggcgcgtcac cgtcccccga agggctcgcg gagggcgagg
    12601 agtcggccgc cgcgggagcc gcggccaggc cgagcagcac tacggccgcg ctcaacgctc
    12661 gggtgaatcg catcagttgg tcctccagat cgcgaaccgc cagcgcgaga gccagcccca
    12721 cagcagaccg gcgacgaagc cgaccagcac cagcaggccg agcagccacc agccgcgccc
    12781 gaggccgaag gcggccacgt cgtcggagtc gcccgggccg tccacgacgt cgacggtcag
    12841 ctccagcggc agacccggcg aggtcttcac gccggaggcc acggagaagg agttggtcac
    12901 ctggaggcac acggcctcgg ccggggcgtc gtcctcgtcg ctctttgcct tcgggtagcg
    12961 cagccccgtc gagagcacgt cggtgcggcc gttgcccgcc gcctcaccgc gcacgatctc
    13021 ccggccgtgc acggtcaccg cgcgcagcag caccccgtag gacgggttca cggcgcggtc
    13081 ggcgcccacg ctcacggagg cgcgcagttc ctggccgggc tccacgtcca cccggtacca
    13141 gcgctgctgc ccgaactcct cgcggtcggt gtacagcccc gacttcagcg tcggcgcctt
    13201 cgcgcacgcg tccgcgccct cggtggccac cggcgtcacc accgggtcgg ccgcccggtc
    13261 caccaactgg ttcaccttgt cggtcagttc gtcggtgtgc tcgaccgagg tgtacgtgcc
    13321 gccggtcgcc tcggcgatgc agctgagctg ctgccgcatc ttggtgttcg ggaccagtcc
    13381 cagcgtgtcg atggtcagcc cgatgccctt ggcggcgatc tcgcgggcca cctcgcacgg
    13441 gtccagcggg gcgcaggtgt cctcgccgtc gctgatcagc acgatccgct tggagccgtc
    13501 gccgccgtcg aggtcgtcgg ccgccttcag cagcgcgggc ccgatcggcg tccagccggt
    13561 cggcgacagg gtcgccaccg ccgtcttcgc ctcggtgcgg tccagcgggc cgaccgggta
    13621 gagctgcgcg gtgtccttgc agccggtctt gcggtcgtcg cccggatagt ccgcaccgag
    13681 cgtccggatg cccagccgca cctcttccgg cgtcgcgtcg agcacctcgt tgaacgcctg
    13741 cttcgccgcc gccatgcgcg taccgccgtc gatgtcccgc gtccgcatcg aaccgctgac
    13801 gtcgagcacg aggtcgacct tcggcgcgtc ctcacccgtg ggttcaccgg cgctcgcccc
    13861 ggccgggaac gccatcccgg ccgccagcgc ggcgagcagg gcacaggcac ccgccgccag
    13921 ccgtgttctt gtgatcatcg gcggatccta ttgatcagtg gtgccgcgct ccaaaacgag
    13981 accgcgccga ggccccggct tcacctccac cgcagtggat tgggcagctc cgtccacaga
    14041 tcgcccgcga tccccggcga agtccgcatc accgtcagcg ccttgaccgg cagcggctcc
    14101 tcgcacaggg ccacgacgtc ctcggtgcgg ggcagttcgg gcaccgccgc tgccagggcc
    14161 gcccgcaggg ccggacccga accggccgtg gccgccagcg cgcctcccac cagcgagccg
    14221 aacaacttcc ggcgcagtgc gagcggttcg tcggtccgta cccgggcggg caggccgtgg
    14281 gccgcgatgc cgtgccgggc caggcgggcc ggggagacgc ggatgtcggc caggtcgcgg
    14341 tagaccaggc gcagcgggtc gcccgccgcg gacagcacga ccaggaggtt ctggccgtgc
    14401 gcctccaggg ccacgcccag ctccagcgcg cgcagcccga cggtgagcgc cagccgggcg
    14461 aagccggcga gccacgcggc ggaacgcggc agtccggtgg tcgccagcgc ggccaccgga
    14521 acgacgtgct cgccgcccga ggcgtacacc tcgggcgctt cgcgcagtac ggcggccagg
    14581 tcgggggagt gggcggtggc cgcgcccagc gtgcgggtca cgtggagcag gccgtccaga
    14641 cgcgccgcca accgctcccc gaacgacgac agatcggccg acgcggcgat cgaggcgacc
    14701 gagatgtccc gcaccgagga cgtcagccgg gcactcagcg cggtcttgac gtgcaccgag
    14761 ccgggcacgg cgagggtccg cagggacatc agcggacgcg cggcgggccc ggtcgcgtac
    14821 gactgcttga gcacgtgcgc ggcctgccac ggatgcaccg ggaccagcac ccgcgccccg
    14881 tcccgcagct ccccgggcca cacccccgtc accaggcact ccgccgccgg gaccggcacg
    14941 agccccagct ccaccaccgg cccgtgctcg ggcccgtagg cgagctgctc cgccaccgag
    15001 aagccgggcc gcgcgcggca accggggtgg tacgggtgcc cgtcgaccac ccgccgctcc
    15061 cagccccagc cgctgtccgg ccactcgtcc gggtgattcc cgggcgcccc ctcccgggcc
    15121 gcccggggct gtgccgcacg cgacagcgcc aaggacgccg cactgtgccc gagttcggcg
    15181 gcgaaggagg ccgagtgcgg tacggccagg tcggtcagca gccgctccgg gtcgtcgtac
    15241 gcgacctcgt ccagccgtac caccggcacg tacgcgtccg tgcggtacgg gtcggcgggc
    15301 ggaccgctca gccggcggcc gtcccgcagg cgcaggacga gcccgtctcc ggaccgctcc
    15361 cggccctcga tccacggcag cggttcgaag gcgagggcac gccacagccg cgacagcacg
    15421 gccgcgcggg cccctggccg ctcggccgcg aaccgggcga tcagagcggg acggacggcc
    15481 gccagctcct cggcgacctc ggccgccgca ctggggggac gatgcacggg caggctcctc
    15541 gggtacgggt cggagtacga gtacgacgtc acggcggagg accgacgact gtcatgacga
    15601 gagacatact gatcgtctcc gtcctctccg ccatggaccg accgtaggga acgagtggaa
    15661 cgcgtggatc tcctgccccc gcccaccggc gccgacgccc ccctcccgga cggcgccgcc
    15721 gcccaggacg acgtggcgcg ccgcgccgac gcccacgcgg ccgtaccgct gctgaactgc
    15781 ctgctgcgcg aggtggccga accgctgccg ggccccggcg cccgccccgt gtaccggctg
    15841 cccggcggca gactgctgcg ggtgcgcccg ggacggcggc ccgccgaacc ggaggtccgc
    15901 acgcagggcg ggtggcaccg ggtcgaccac gccgaactgg tgaagctcgt cgccgaggcc
    15961 ctgcgccggc acaccggagt gcccaaccac gaactgccca ccgagatgac cgacagccgc
    16021 gacgcgatgg ccgccctgct gacggcacgc gcgcgtgcca ccccgcccgc cgacccgtac
    16081 ctccgctccg agcaggccct gctcaccggc cacacccacc atcccgcccc caaggcacgc
    16141 ggcggcggcc cgcacgccgg gtggctgccg tacgcgcccg aggcacacgc ccgcttcccg
    16201 ctggcgctgc tcgccgtgcg cgaggacacc gtcgtcgacg agggcgacac cgccgccctg
    16261 gacgccctcg gcaaggcccc gcccggctac cggctgctgc ccgcccaccc ctggcagctg
    16321 gagctgacgg caccggccct cgcccccgcc ttcgccgacg gcaggctcgt ccgggtgggc
    16381 acgaccggct tcttcgcctg gccgacggcc gcgatccgca cggtgtacgc gcccgagtac
    16441 ctgcccggac gggacctctt cctgaagttc agcctcgacg tgcgcgtcac caacgacatc
    16501 cgccgcctgt ggcgccacga cctgatgcga ctgcgccgca ccgacaccgc ggtcaccgag
    16561 gccttcgcct ccgtcggacc ccccgccgcc tggctcgccg accgcggcca ccgcaccgcg
    16621 gacttcgcct tcgaggaact ggccgtcgtc gtccgcgacg gcctgcgcga ccacctcctg
    16681 cccggcgcga ccccgctcct ggccgccgcc ctcgtggagg gcttccccgg cagcccgctg
    16741 accgccaccg cggacccggc ggcctggtgg gaggcgtatc tcgccgccgt cgtgccgccc
    16801 gtcctgaccg ccttcgccga cgacggcgtc gtcctggagg cgcacctcca gaacaccctg
    16861 gtcgccgtgg acgcgaccgg catgccggtg caggccctgt tccgggacgc ggagggcgtc
    16921 aaactgctgc cggacacccc ccgggcggcc ggctgggaac gcctggtcta ctgcctggtc
    16981 gtcaaccacc tgtacgagat cgccgccgcc ctcgccgaac accaccccgg cctcgacccc
    17041 tggcccgccg tccgccgtga actggcccgc cacgacatcc ccgagatccc cgcgctgctc
    17101 accgcccccg ccctccccgc caagaccaac ctgctgctgc gctggaccgg cgcggacggt
    17161 gccgacgccc gctaccgccc cctggccaac ccgctgcgcg gggcctgagc ggccactggc
    17221 cgccgcgccc ggaaatcccg tgccgtaccc ctccccggtg gggcacactc accgcatggc
    17281 ggacatggac gcgttccggg acgagatcgc ccgctgggcg gcgggcggcg ccggggacac
    17341 ggcggcggag ctggcggcag gcctcggact gcggacggcg gtgctgctgg agggccccag
    17401 cgacctcgcc gccgtccagg ccctggccgc ccgcgaggac cgcgacctgg ccgccgaggg
    17461 cgtggccgtg gtgtccatgg gcggcgcgat gagcgtcggc cgctacgccg gcctgctcgg
    17521 cccgcccggc ctcggcctgc gcctgaccgg cctctgcgac gcccgggagg agcccttcta
    17581 cgtccgcggc tggcagcggg cgggcgccgc gcgcgacttc cacgtctgcg tcgccgacct
    17641 ggaggacgag atgatccggg cgctgggccc ggcgcgggtc gaggaggtca tacggtccga
    17701 ggacgaactc cgcccctggc agaccttcct ggcccagccc gcccagcacg gccgcccccg
    17761 ggaacagcag ctgcgccgct tcctcagcac gaagaagggc cgcaagatcc gctacggcag
    17821 cctcctggtg gaagccctcg acggcggacg gccaccggcc ccgctggcgg atctcctcgc
    17881 ggggttgtga ccgtcggcta cttcgtggcc ccctgggcga agccgttgta gatgtagcgc
    17941 tggaggaaca ggaagatcac cagcgtcggc acgatgacga ggacggcccc ggcggagatg
    18001 ttctcccagt gcgccccgaa gggccccttg aaccggaaga gggcggtcga catggtcccg
    18061 agatcctcgt ccggcatgta gaggaacggg atgtagaagt cgttgtacgt cgtgatgccc
    18121 ttgatgatga ccacggtcgc gacggccggc ttcagcagcg gaaagatgat cttccggtag
    18181 atggtgaagg agttcgcgcc gtcgagtcgc gccgcctcgt cgagggaccg gggtatgccg
    18241 cggatgaact gcaggaagat gtagatggcc acgatgtcgg tgcccatgta cagcaggatc
    18301 ggcgcccagc gggtgttgaa cagcccgaag ccgttgacga cctggaaggt ggcgacctgg
    18361 gtcgtcaccg ccggcaccag cgtggcgatc aggaacagcg ccatgacgag cttcttgagg
    18421 cggaagtcga agcggtcgat ggcgtacgcg gtcatcgagc cgatgatcac ggtgccggtg
    18481 atggagaaca gcaggatgaa ggcggtgttg ccgaaggctt gcagaaggtg gccgtcgctg
    18541 aaggcggtgg cgtagttgga gaagttgagc cagtcgtcgg gcggggccag ggcgccctgg
    18601 ccgtcggaga cctccccgta ggacttcagc gaggtcagga agaccacgag aagcggcagc
    18661 agcaccacgg cggacgcgac gaccagcgac aggtacgtca gggcggtgct gatgcgcgga
    18721 cggctgcgcg gacggctgcg cggccgttcc tgcgggcgga cgggggccgt gagggtcata
    18781 cgaggtccac cttctcgtcg ggcacgaggc ggcgctggat ccaggtgatc agcaggatga
    18841 tcgccagcag caccaccgca caggccgagg ccaggccggt cttgttgaac tggaaggcgt
    18901 acttcaccgt ctggatgacg aacgtcgagg tctccgtcgc gccgccggtc atgatgtacg
    18961 ggatctcgaa gacggagagc gagccggaga tcgccaggat gacgctcagg ctcagcaccg
    19021 gccggatgct cggcgcgatg atgtgccgga actgcttcca ccggccggcg ccgtccagtt
    19081 gggcggcctc gtacagctcg ccggggatcg actggatcgc gccgaggaac agcacgaagt
    19141 tcaggccggt gaaccgccac acggacaccc cggccatgga ggtgttggcc gactcgggac
    19201 tgcccagcca ggcgtggtcg gtgccggcgc cgaaccagga aaggaccgag tcgagggtgc
    19261 cgccgtcctg gaagaagtac aggaagacga agccgatcgc gacgccgttg atcaggtacg
    19321 ggaagaacag gatgcccttg aacaggttcc tgaagcgcag gtcgaagctg aggacggcgg
    19381 cgaagtacag ggcgatgacg atctgcacga cggacgccgc caggtagtag aagctcaccg
    19441 cgaacacccg gagcagctcg gggcgggtga agatctcggt gtagttctcc gcgccgacgt
    19501 agtcgcggtc ggggctgaca ccgtcccagt cggtgaagct gtagtagatc atgttgccca
    19561 ccggcacgta cgtgaacgtg atcagcaggg ccagcggtgc cagtaggaac agccacgggg
    19621 tgagcttgcg cagcggccgg ccgcgccacg gggagccggc ccgtgcgcga tgccgggagg
    19681 gtcgtttccc ggtccgcccc ggcccggcgg ccggggcggg tggcgaagcg gtggaagcgg
    19741 ttcgggtcat tgcggagcca gggcctttcg tcgtccgccg agggcgccgg ggtcaggaac
    19801 cgaccgtctg cctggccgct gaccagcgct tgttcaggtc gtcgaagtag ccctccaggg
    19861 acccgtccgt gacgccgcgg gcgatgtcga tgagcttctt gcggtagtcc ggcttgttga
    19921 gcccgatctc ggaggcgttg tcgatggcgt tgacgtcggc cgtcttcgcc tcggaacgct
    19981 caatcatctt gacatcgttg tcaacgtagt cctggagcgt ctcaggcatc ccctccgact
    20041 tcagggcgga gacggcgccc tcctcggccg cgtacccgga cttctcggtg aaccagtcga
    20101 tccacgcccg ggcggcctcc ttgtggtcgg agtggatgtt gaccgcttgc tggtagtcgg
    20161 agaccagggt ggcgcagaac gtgccgttct tctgggacgg caccggcatg aagccgatgt
    20221 cgtccgggtt ctgcccggcc gcctcggccg cgtcccgcat ctggttgacc gcccaggagc
    20281 cgagcatcat gctccccacc cggcccttgg ccaggagggt cttggaactc tcccagttgg
    20341 tggtggccgg gtccttctcc gagagcttct cgtggacgat gtcgtagagc agcgtgtcga
    20401 gggtgttgag gtcgttgccc tcggtccagg gttcgtccat ggcggccagc ttgtcggagg
    20461 cctggctgtc gcagctgatc gagccgacgc cgttggtcca gggactctcc agcggccagc
    20521 cgtccttgaa gttggtgtag tacggggtcg ccccggtctt ctccttgacg gcctcgaggt
    20581 cgtcgaggaa ccggccggtc gtcgtcggcc agtcggtgat cccggccttc ttccacagtg
    20641 ccttgttgta gacgaggccg ttggcggttc cgaaggtggc gatgccgtag gtcctgccgc
    20701 cgacgtccgt cttgtcggtg aagcggtact tcggctccat cgacgaggtc tcgccgagcg
    20761 gggcgaagaa cttcgggtag tcgcccttgg cgaccgccga cgggatcagc aggacgtcgc
    20821 cgtagtcctc cgtgttcatc cggatcttca cctccccctc gtagtcggtg aggccctcga
    20881 actcgacctt cacgtcgggg taggtcttgt tgaactcggc ggcgtacttc ttcatcgtcc
    20941 cgtcctcgac caggtcggtg cgattggtca gcacggtgat gtcccccgag acgccgtccg
    21001 ggttgaccgg cgcggcggcg gtctcgccgg cgtccgcgcc gcctcccgcg ccgcaccccg
    21061 cgacggtcag catcgtggtg gcgagcagtg cgacgctcag cgtcctcttc cccatgtgcc
    21121 cagctccttt ccaaggatca cggctcgggc tccggtgtgg tgacggcgac tatgtcagcc
    21181 gctcgttaac cggtaaagct cgtgcatctc tcgcgatatc caatcgttac ctctggaagt
    21241 gcagggggct tggtcgaacc atgcctcgga gggttgggcg tcggtgctct cgtcgagcgg
    21301 tcaggactag accggttcac ttccctggcg ttaggttgag gcgcgttgcc cacgacaccg
    21361 ggtccgtccc gccgaaggag ccgtacatga aggaagtcgt cccgctcgcc gagggctgga
    21421 gcctccgcca cagcgatgac ctgctgcccg cccaggtccc cggctgcgtc cacaccgatc
    21481 tgctcgcggc cggcctgatc ccggacccct tcctcggcgt caacgagtcc gacgtggcct
    21541 gggtcggaca gcgggcctgg acctacgtcc gcgacctgcc ggccacctgc accgataccg
    21601 ccaccgccgc gcccgagcac gagcggacgg acctggtctt cgacggcctg gacaccgccg
    21661 cgaccatcac cctgaacgga cgggaactgg gccgcacccg gaacatgcac cggcgccacc
    21721 gcttcgacgt caccgggcgc cacgggctgc tggaggtgga cttcgcctcc gcgtacgacg
    21781 aggcgacctc ggtgcgggca ctgaccgggg agcgccccaa cgtctacccg gaacccttcc
    21841 agtacatccg caagatggcg tgcggcttcg gctgggactg gggtccgacc ctggtgaccg
    21901 ccggtatctg gcgcccggtc cggctggagc ggtggtcgac ggcccggctg gccggcgtac
    21961 gcccgctggt gacggtccac ggcggcaccg gccgcgtcga gctgcgggtg gaggtcgagc
    22021 ggaccgcgca gggggcggcc cgcccgctcg ccgtgcgcgc caccgtcgga agcggactcg
    22081 ccgaggcgcg cggcgcggtg gaggggacgc acgtggtgct gacacttcag gtgcccgacg
    22141 ccgacctgtg gtggccccgc ggctacggcg gccagcccct gtacgacctg gaactcgcgc
    22201 tcgtcgaaga agccgccggt cccggtggcg aagagcgccc cctcgacacc tggcaccggc
    22261 ggatcggctt ccggaccgtg gaagtggacc gctcggcgga ctcgcacggc accggattca
    22321 ccctcgtcgt caacggcgaa cgcgtcttcg cacgcggcgt gaactggatc cccgacgacg
    22381 tcttcccgtc ccggatcacc ccggagcgct accgcacccg gctgcgccag acggccgacg
    22441 cgggcgtgga cctggtacgg atctggggcg gcggcatcta cgaggacgac gccttctacg
    22501 acgcctgcga cgaactgggc ctcatggtct ggcaggactt cctcttcgcc tgcgccgcct
    22561 acccggagga gcagccgctg cgcggtgagg tcgaggccga ggcccgcgac aacgttgtcc
    22621 ggctcatgcc gcacccctca ctcgtcctgt ggaacggcaa caacgagaac ctctggggct
    22681 tccgcgactg ggactgggag cccgagctgc gcggcgactc ctggggcggc ggctactacc
    22741 tggacctgct cccgcggatc gtcgccgaac tcgaccccac ccgcccctac accgcgggca
    22801 gcccctggtc cggctcctgg gaccaccacc ccaacgaccc ggcccacggc acgtaccact
    22861 cctgggaggt ctggaaccgc cgcgactacg ccgagtaccg cgactcggtg ccccggttcg
    22921 tgtcggagtt cggctggcag gcgccgcccg cgatggcgac cctgcggcgc gcgctgcccg
    22981 gcgaacggct ggcgcccgac tcgcccggca tgctgcacca ccagaaggcc gaggacggca
    23041 acggcaagct caaccgcggt gtggaacgcc acttcgaact gcccgagggc gacttcgacc
    23101 gttggcacta cctcacccag gtcgtgcagg cccgcgcgat cgccaccggg atcgagcact
    23161 ggcgctcaca ctggccggtc tgcgcgggca ccgtcgtctg gcagatcaac gactgctggc
    23221 cggtcagctc ctggtcggcc atcgatggcg acggccggct caagccgctc taccacgagc
    23281 tgcgccgggt ctacgcggac cggctcctca cggtgcagcc gggtgacggc cacgggggcc
    23341 cgcccgtgct cgccgtcgtc aaccagtccg ccgaaccctg gcaggcccgc gtgaccctgc
    23401 gccgcctgcg cgcggacggc accgaggcgg ccgggcgcgc gatcgacgtg accgtgcccg
    23461 cccgttcggt gcaccggcgg accgtgccgc aggaactggc ccccgcccct cggtcggcca
    23521 aggagttcct cgtcgccgac agcgaggatc tgcgcagcgt gcacttctgc gtgacggacc
    23581 gggacttcgc ctacccggta ccgcactacg acgtggccgt ggagtccccg gtgggatccg
    23641 gtaccggtaa tgtcgaggtc gtggtaaccg cacacaccct cgtacgcgac ctcctcctcc
    23701 aggccgaccg actcgggccg gacgcggtct gcgacaccgg actgcgcacc ctgctccccg
    23761 gcgagcggct gcgcctgcgg gtcacgggcg cggccgagac cggggccaac gccgtacggg
    23821 cggctctgtt ctgcgtggaa ccggcgtgag tacaccgtcc gtccgcgtga ccatcaagga
    23881 cgtcgccgcg gccgccggtg tgtccaaggg cgccgtgtcc ctggccttca acgacaagcc
    23941 gggcgtctcc gacgccaccc gcgaacggat cttcgcggtg gcccggcagc tgggctgggc
    24001 cccgaactcc tcggcccgca gcctgtcgcg ccagtccgtc gacaccgtgg ggctggcgat
    24061 ctgccgcccc gcgcggctgc tgggcctcga gccgttctac atggagttcg tctcgggcat
    24121 cgagagcgtg ctggccgaac gcgactgctc gctgctgctg cgcctggtcg gctccctgga
    24181 agaggagatc gggctccagg aacgctggtg gcgggagcgg caggtggggg gctcgatcct
    24241 ggtcgacttc caccaggagg atccccggat cggcccgctc gggcggatcg gcctgcccgc
    24301 cgtggcggtc ggccacccgt ccctcaccgg cgggttcccg tcggtgtgga cggacgacgc
    24361 cgccgccgtc gcggaggcgg tgcgctacct ggcggtgctg ggacaccggc gcatcgcgca
    24421 cgtgggcggt ccccgggggc tcgggcacag cgcgatccgg acgacggcgt tcgaacggac
    24481 cctgagcgaa ctcgggctcg accgcgggcc gcacgtcgag acgggcttct cgggcgagga
    24541 cggcgcgcgc gccacccgct ccctgctgct gtccgccgag cggcccacgg cgatcctcta
    24601 cgacaacgac atcatggccg tcgccggact cggcgtcgcc gccgagatgg gcgtctccgt
    24661 gccggacgac ctgtcgctgc tcgcctggga cgactcccag ttgtgccggc tgacccatcc
    24721 gacgctgtcg gcgatgagtc acgacgtgca cggcttcggc gcgcaggtga cgcgggtgct
    24781 gttcgacgtg ctggcgggca aggacgtgac gtcccggccg gtggcgactc cgtcactggt
    24841 gccgcgggcg tcgacggcgt cgccgcgttc gtagcggcgg aacggccacc gggaggggcg
    24901 cggcatcatg tcgcgcccct tctttttgct aaaccgctaa acgcgctgac cagagtgtga
    24961 agcccgcgta tccaggtcgt tcacctgcgt caactgcccc tgcatgacgg attgacaggc
    25021 ttgccaggtg tccctacggt ccctatcggt taaccggtaa atgtccgccc cggggtgcgg
    25081 gacaacgttg tcaggtgcat gctcgcccgc catcgaagga gacacatgcg taagccaaga
    25141 agcacgctga tcacgaccgc ggggatggcg ttcgccgccg ttctgggcct gctgttcgca
    25201 ctcgccggtc cttccgccgg aagggcggag gccgcggccg gtggcatcca cgtcagcaac
    25261 ggacgtgtcc tcgagggcaa cggcagcgtg ttcgtcatgc gcggggtcaa ccacgcctac
    25321 acctggtatc ccgaccgcac cggctccatc gccgacatcg cggccaaggg agccaacacc
    25381 gtccgcgtcg tgctcagcag tggcggccgc tggacgaaga cgagcgcgtc cgaggtctcg
    25441 gcgctcatcg gccagtgcaa ggccaacaag gtcatctgcg tccttgaggt gcacgacacc
    25501 accggctacg gcgaggacgg cgccgcgacc agcctggacc aggcggccga ctactgggtc
    25561 agtgtgaaga gcgcgctgga gggccaggag gactacgtcg tcgtcaacat cggcaacgaa
    25621 cccttcggca acaccaacta caccgcgtgg accgacgcga ccaagtcggc catcggcaag
    25681 ctccgcggcg ccggcctcga ccacgccctg atggtcgacg cgcccaactg gggccaggac
    25741 tggtccggca cgatgcggtc caacgcggcc tcggtcttcg cctccgaccc cgaccgcaac
    25801 accgtcttct ccgtccacat gtacggggtc tacgacaccg ccgccgaggt gcgggactac
    25861 ctgaacgcct tcgtcggcag cggactgccc atcgtcgtcg gtgaattcgg cgaccagcac
    25921 agtgacggca accccgacga ggacgccatc atggcgacgg cccagtccct cggcgtcggc
    25981 tacctcggct ggtcctggag cggcaacggc ggcggcgtcg agtacctcga catggtcaac
    26041 ggcttcgacc cgaactcgct gacgagctgg ggcaaccgca tcttctacgg cagcaacggc
    26101 atcgccgcga cgtccaggac ggccaccgtg tacggcggtg gtggcggcag cacgggcggc
    26161 accgcgccca acggttaccc gtactgcgtg aacggcggtg cgtccgaccc ggacggtgac
    26221 gggtggggct gggagaacag ccggtcctgc gtcgtccggg gcagcgcggc ggaccactga
    26281 cccgaccgac ggcgacgccc caccctgggg ttccggggcg gggcgtttcc agtgggcggc
    26341 cggtcagcgg tcggtcgtgt acgtgaggaa gcgggtccac gccgtggggg agacggcgag
    26401 ctggtcgccg tgcggcgcct tcgagtcgcg gatgtggatc gtgtccgggc gggccgccac
    26461 ctcgacacag tcgccgtcac cgctgctgct gtagctcgac ttgtgccagg acagggcgat
    26521 ttccacgcgg tcgccgtcgc caccgctgct gtacgagctt ttgaaccagg ccagttccgt
    26581 cgtgttcatg aggctcctcg catccgccgc aacaggccca gggagtcgtc gagggagagg
    26641 gcctgtgatc gcatcctggc atacctcatc tggaggacgc tgacctcctt ccgctcggag
    26701 acgaacaggc caccgcgttg cccctcgttg tacgcgaacc agcgtgcctc gggcgtctcc
    26761 aggagctgca ttggaccggc catgcctgcg tgcgcgttcc gtaccaaggg catcacctgc
    26821 acctccacgt tccgtagctc tgccagtccc agcacgtggt cgatcagctc ccgggtcacc
    26881 tgcgtcccgc ccatgcgccg caggaacaag tgttcctcca gaatgaagct gaacgccgtg
    26941 ttcggcagct ccctcagcag ccgctggcgt tccgcccgtg ccacccactg ggcctcgatc
    27001 tgatcgtcgc ccaatggtgg cagttggttc gtgaacagcg tgcgcgcgta ggcctcggtc
    27061 tgcaacaggc cgggaatgag gcggcattca tacgtataca gactcaccgc ctccgcctcg
    27121 aaccgcgccc actgccggaa ccagctggcc agccctggtt gccgcgacag gtgccgtgcc
    27181 gcacctcgca gcgcgccgaa cgcgtcgagg gctgcctccg cgcgctccac gaagtccacc
    27241 ggagggaacc gtcgcccctg ctcgatggag gccaccgtcg gaaccgagta ccgcacttgt
    27301 ggcgcgaact cctcctgggt cagccccgcc cgtttgcgga aagccttgac gacctcgccg
    27361 aacgccttga ggctgtccga cgcctccggt tcacccgcgc cgcccgtacc gtccgtcatc
    27421 cgggacacct cccacccgtc acgcccactc aacgggccca tggtcacgga cggttactct
    27481 tactgtccac cgtccgcacc cgtacgctca ccgtgcgtac cggtcgctga tctggtggga
    27541 cggcgtcacc ccaggtggga tgggggcatg agaccagcct ccactccccg actcccggtc
    27601 accgcgcgtg tgttcgtcca gcggttcagc tccactccgc gcggcgcccg cctggcccgg
    27661 catctcgtcg tgcaccgtct ggacgcgtgg ggcgtcccgt acggctcggc gctgtccgac
    27721 acggcggcgc tgctcgtcgc ggagctggcg gcgaacgccg tgacgcacgg gcgggtgccg
    27781 gggcgggaca tcgaggtgct gctgcggctg gacgcgtaca cgctgcggat cgacgtgtcc
    27841 gacagccggg gtgagcgccg cccgatggtc acggcggtca cggcggcccc ggaggccgag
    27901 cacgggcggg ggctgctgct cgtggacgcg ctggcggacc ggtggggcgt gttcgaccgc
    27961 gtacccgtcg gcaagacggt ccgcgcggaa ctggatctgc cgcctcgcga ccaaagatcc
    28021 cgcacggccg atgacttcgc gcgggaatga gagtctcctt cacgaccccg gtccgtgaga
    28081 tgacgacagg agaccttccc gcatgactga tccggagctg accgcggaac gcggccaagg
    28141 gacgggcgtc tggcccttga tccgtacgga gcgggcggcg ctggccgccg atctcgcgga
    28201 gctgaccggc gagcagtggg cgacgccgtc gctgtgcgcc ggcctgacgg tgcgcgaggt
    28261 gctggctcat ctcacggcgg gcgcgagcct caacaccgtg cgctggttcg cgggggtgat
    28321 ccgctgccgg ttcgacttcg acaagcaggt ggccgtgcgg ctggccgagc agttgggcgc
    28381 ggatccggcc gagacgctcg cccgattccg gcgcgtcgtg ccgagcacca ccaagccgcc
    28441 cctgcccgcc atcgccatgc tgggtgagac gctggtgcac ggtgaggaca tccggcgtcc
    28501 gctgggcatc cgccacgact acccggtcgg cgtcgtcacg cgcgtggccg agtactaccg
    28561 gggctcggac ctcgtggtcg tcgccaagaa gcgcatcgaa gggctgagac tggccgcgga
    28621 cgacgggccc ttcaccaccg gctccgggcc cgtcgtgtcc ggccccacca tggccctggt
    28681 gatggccatg accggacgcg agacgtactg cgacgacctc gaaggggacg gtgtggaact
    28741 cctccgcgac cgctgccgga cgccgtgaac gcgtccccgg tccctgggag ccgttctggc
    28801 gaccatgtgc ggagccggat tggtaaaggc cgcagcggtt gcgtttcttg taccgctctt
    28861 cgtcgaagcc gggtggacgt ccgccgtgac accgtttggc ttcgtgcgcg gcccgccccg
    28921 gccggacttc gcaacgcgga tcttctccag caccggcctg gcctgggtag gtcgtcagtc
    28981 tgagacgatc agtcagtcga gtggccaatt cgtcagcttc attggattca gcatgagcca
    29041 cacgttcgtg acgcattcac cactgacgtc aaatgtgacc attccgtatc ggcgctcttc
    29101 gtctcgaaga atgtatccga gaccgtcagc tgtttcgcgt cgttcaaggc ggaggccggg
    29161 ctgtttgcgc atgactccct ggaaccaccg ggccacgtga ttcgacccgt ggatgacctt
    29221 aggcgcggca ttgacgaagc caccgccgtc tactcgtagt tcgacgtctg gagccaacac
    29281 gcggagcagg tcctcgatgt cccctccgac agttgcgtca cggaaagccc gaacgacctc
    29341 atcgtgctgg tggggagaaa cccgtgcgcg tcttcctcgt cgaacgtggc ggcgtgcgga
    29401 cgtcgccaat tgtcttgttg ctgccgctga acgacctacg acaccagcga tctcgccaaa
    29461 cgggacgccg aacacgtcat gcagcacgaa cgtcactcgc tccgctgggg tcatggcctc
    29521 gagaaccgtc agcagtgcca tgctgacggc atcatcgagg gtgacgcgat cgagtggatc
    29581 agcagcagaa ctaccggagt tcagtggcgc cttcgctgtg tcggcaaaaa ggtcggccgg
    29641 aacgggctcc ggtagccatt gcccgacgta catctcccgt cgtgcccgcg cggaacccag
    29701 caagtcgagt gagatgcggc tggcgactcg catcagccat gctgcgggca cggcaatgct
    29761 gtcgcgttcc tcgggctcaa ggcggtacca cctgacatat gtctcttgta cgacatcctc
    29821 ggcatcggcc agggtgccca tcatgcgaaa ggccagcgac agcaggcgat gtcgctctgc
    29881 catgactgaa tcgagagctg ttgattcatc accctcggct cctccgaact cggcggattc
    29941 cgcaggtgtg tcttccggca tggggcaccc tttcccattg gagtgcagcg cgcccagccc
    30001 atagcctggc gctcaggcgt tcctcctcca ttcactatcg cattcagacg gtggggatcc
    30061 ctgtaatcgg gtaccgcaca gtgcctgtcc ggtacgcgcc gcgcggaacc atgacgtcgg
    30121 gtgccccttc cgcgtccacg gtcaccacct cacgatcgtc tccgcggtca gccagagtgg
    30181 cacggaagag gtcgtcgtgg taaaagcggt cgggtccggc gatctcgacc tcgcttcccg
    30241 gttccagcgt cgtggcagcc tcggcgagca gctcgatgac ttcgtccagc tcgacgggct
    30301 ggacgaatga ccttggagca ataaccttgc cgtccacggt gtgctggtcg atgaggacag
    30361 gaatgtagct ctggaactgg gtggcccgaa tgatggtggc ggggatcgaa gcggatcgca
    30421 cggccttttc ctgcgccacc ttgccgaggt agtacccgac ctcagacgcg tccccttgcc
    30481 caacgccgac gatggagagc acgatgtgat gacgcacgcc tgcccgctct ccctccgcag
    30541 tcaggttgtt gatcgctccc tcgaagaacg agattgcccc ctccgcatca aagcgggggg
    30601 tgttgaggac attgacgatg gtgtcgactc cggcgagagc ctcggtcagc cccttgcccg
    30661 agatgacgtc gatcccgtcc tcaagccctc ccgagaccac ctcgatgccc ttggcctcca
    30721 ggttgtcagc aaggagggac cccacgcggc cgcgcccacc agcgatgaaa accttcattt
    30781 tccgtactcc gttccggggc accagtcgct gccctcagca acatgacgac gcaggccgga
    30841 agaatgtgag gttgcgacgg cggagtctcg tcgccccctg atggaggcgt gcagacgacc
    30901 gggcgaccga ctggctccag cccgccagag cagtagccgc tcgctccggc aagcgcggct
    30961 acgccttcct ccggatcgcg accgccgaag ccccgtcatc tggctccgtg catgatcggc
    31021 cgggcacgtc atcgttaccg aaacggtcat gaggtctgcg gctgccgtcc gcggagctgt
    31081 tcggtcagcc gctcgaccgg cccgggcgag gacacggtcc gcgagcgcta cctcgcggcc
    31141 ttcgcgcgcg tcctgcccgg cctttccccg gaggagctgc ggttccggat gcgggggatc
    31201 ctcgccgt
//
