LOCUS       NC_003888              11317 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    RefSeq; complete genome.
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces
            albidoflavus group.
REFERENCE   1  (bases 1 to 8667507)
  AUTHORS   Hsiao,N.H. and Kirby,R.
  TITLE     Comparative genomics of Streptomyces avermitilis, Streptomyces
            cattleya, Streptomyces maritimus and Kitasatospora aureofaciens
            using a Streptomyces coelicolor microarray system
  JOURNAL   Antonie Van Leeuwenhoek 93 (1-2), 1-25 (2008)
   PUBMED   17588127
REFERENCE   2  (bases 1 to 8667507)
  AUTHORS   Bentley,S.D., Chater,K.F., Cerdeno-Tarraga,A.M., Challis,G.L.,
            Thomson,N.R., James,K.D., Harris,D.E., Quail,M.A., Kieser,H.,
            Harper,D., Bateman,A., Brown,S., Chandra,G., Chen,C.W., Collins,M.,
            Cronin,A., Fraser,A., Goble,A., Hidalgo,J., Hornsby,T., Howarth,S.,
            Huang,C.H., Kieser,T., Larke,L., Murphy,L., Oliver,K., O'Neil,S.,
            Rabbinowitsch,E., Rajandream,M.A., Rutherford,K., Rutter,S.,
            Seeger,K., Saunders,D., Sharp,S., Squares,R., Squares,S., Taylor,K.,
            Warren,T., Wietzorrek,A., Woodward,J., Barrell,B.G., Parkhill,J. and
            Hopwood,D.A.
  TITLE     Complete genome sequence of the model actinomycete Streptomyces
            coelicolor A3(2)
  JOURNAL   Nature 417 (6885), 141-147 (2002)
   PUBMED   12000953
REFERENCE   3  (bases 1 to 8667507)
  AUTHORS   Redenbach,M., Kieser,H.M., Denapaite,D., Eichner,A., Cullum,J.,
            Kinashi,H. and Hopwood,D.A.
  TITLE     A set of ordered cosmids and a detailed genetic and physical map for
            the 8 Mb Streptomyces coelicolor A3(2) chromosome
  JOURNAL   Mol. Microbiol. 21 (1), 77-96 (1996)
   PUBMED   8843436
REFERENCE   4  (bases 1 to 8667507)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2002) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
  REMARK    Direct Submission
REFERENCE   5  (bases 1 to 8667507)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2002) Sanger Institute, Wellcome Trust Genome
            Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
  REMARK    Direct Submission
COMMENT     ##antiSMASH-Data-START##
            Version     :: 8.0.1
            Run date    :: 2025-05-26 12:13:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start :: 6632342
            Orig. end   :: 6643659
            ##antiSMASH-Data-END##
            REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..11317
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="18"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11317
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11317
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6317](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6317)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    102..116
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: strong, score: 27.49"
                     /tool="antismash"
     gene            152..1636
                     /db_xref="GeneID:1101482"
                     /gene_synonym="SC1B5.01; SC1C3.29"
                     /locus_tag="SCO6041"
     CDS             152..1636
                     /codon_start=1
                     /db_xref="GeneID:1101482"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC1B5.01; SC1C3.29"
                     /locus_tag="SCO6041"
                     /note="SC1B5.01, possible hemY, protoporphyrinogen oxidase,
                     partial CDS, len: > 468 aa; similar to many e.g. HEMG_BACSU
                     P32397 bacillus subtilis. protoporphyrinogen oxidase (470
                     aa), fasta scores; opt: 741 z-score: 711.8 E(): 2e-32,
                     32.9% identity in 453 aa overlap; SC1C3.29, possible hemY,
                     protoporphyrinogen oxidase, partial CDS, len: > 61 aa;
                     overlaps and ecxtends CDS from overlapping cosmid,
                     SC1B5.01"
                     /product="protoporphyrinogen oxidase"
                     /protein_id="NP_733684.1"
                     /transl_table=11
                     /translation="MSASETPAGEFPPEQEPGHVVVVGAGIAGLAAAHRLLEAGARVTV
                     LEASGRVGGKLLPGEIAGVRVDLGAESMLARRPEAVGLARAAGLADRLQPPSTATASLW
                     TRGALRPMPKGHVMGVPGTAAALSGVLSEEGLARIERDAELPRTEVGDDVAVGEYVAAR
                     LGREVVDRLVEPLLGGVYAGDAYRISLRSAVPQLFEAARTHTSLTEAVRALQGRTATSP
                     PSGPVFMGIEGGIGTLPPAVADSVRARGGEIVTQAPVTELRRTASDGWRIVAGDRVLHA
                     GAVVVAVPAGPAAELLRAEAPAAAAELSAVEYASMALVTLAYRRSEAAALPEGSGFLVP
                     PVDGHTIKASTFASRKWGWIADEDPDLVVLRTSVGRYGDTEILGRDDAGLVAVSRHDLA
                     EATGLTAAPVATRVTRWQDGLPQYPVGHHARVARVREHVAKLPGLAVCGAAYDGVGIPA
                     SIASAYAAADQIRGDLGGVEELTAHPVQSLHGGAGE"
     aSDomain        206..1561
                     /aSDomain="TIGR00562"
                     /aSTool="tigrfam"
                     /description="proto_IX_ox: protoporphyrinogen oxidase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6041_0088"
                     /evalue="1.20E-63"
                     /identifier="TIGR00562"
                     /label="SCO6041"
                     /locus_tag="SCO6041"
                     /protein_end="470"
                     /protein_start="18"
                     /score="213.3"
                     /tool="antismash"
                     /translation="HVVVVGAGIAGLAAAHRLLEAGARVTVLEASGRVGGKLLPGEIAG
                     VRVDLGAESMLARRPEAVGLARAAGLADRLQPPSTATASLWTRGALRPMPKGHVMGVPG
                     TAAALSGVLSEEGLARIERDAELPRTEVGDDVAVGEYVAARLGREVVDRLVEPLLGGVY
                     AGDAYRISLRSAVPQLFEAARTHTSLTEAVRALQGRTATSPPSGPVFMGIEGGIGTLPP
                     AVADSVRARGGEIVTQAPVTELRRTASDGWRIVAGDRVLHAGAVVVAVPAGPAAELLRA
                     EAPAAAAELSAVEYASMALVTLAYRRSEAAALPEGSGFLVPPVDGHTIKASTFASRKWG
                     WIADEDPDLVVLRTSVGRYGDTEILGRDDAGLVAVSRHDLAEATGLTAAPVATRVTRWQ
                     DGLPQYPVGHHARVARVREHVAKLPGLAVCGAAYDGVGIPASIASAYAAADQI"
     PFAM_domain     230..1561
                     /aSDomain="Amino_oxidase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01593.27"
                     /db_xref="GO:0016491"
                     /description="Flavin containing amine oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6041_0696"
                     /evalue="4.00E-48"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO6041"
                     /locus_tag="SCO6041"
                     /protein_end="470"
                     /protein_start="26"
                     /score="165.0"
                     /tool="antismash"
                     /translation="IAGLAAAHRLLEAGARVTVLEASGRVGGKLLPGEIAGVRVDLGAE
                     SMLARRPEAVGLARAAGLADRLQPPSTATASLWTRGALRPMPKGHVMGVPGTAAALSGV
                     LSEEGLARIERDAELPRTEVGDDVAVGEYVAARLGREVVDRLVEPLLGGVYAGDAYRIS
                     LRSAVPQLFEAARTHTSLTEAVRALQGRTATSPPSGPVFMGIEGGIGTLPPAVADSVRA
                     RGGEIVTQAPVTELRRTASDGWRIVAGDRVLHAGAVVVAVPAGPAAELLRAEAPAAAAE
                     LSAVEYASMALVTLAYRRSEAAALPEGSGFLVPPVDGHTIKASTFASRKWGWIADEDPD
                     LVVLRTSVGRYGDTEILGRDDAGLVAVSRHDLAEATGLTAAPVATRVTRWQDGLPQYPV
                     GHHARVARVREHVAKLPGLAVCGAAYDGVGIPASIASAYAAADQI"
     regulatory      1628..1631
                     /gene_synonym="SC1B5.01; SC1C3.29"
                     /locus_tag="SCO6041"
                     /note="possible RBS upstream of SC1B5.02"
                     /regulatory_class="ribosome_binding_site"
     gene            1641..2372
                     /db_xref="GeneID:1101483"
                     /gene_synonym="SC1B5.02"
                     /locus_tag="SCO6042"
     CDS             1641..2372
                     /codon_start=1
                     /db_xref="GeneID:1101483"
                     /gene_synonym="SC1B5.02"
                     /locus_tag="SCO6042"
                     /note="SC1B5.02, unknown, len: 243 aa; similar to
                     hypothetical protein downstream of M. tuberculosis HemY;
                     TR:P71973 (EMBL:Z80225) MTCY441.45C (296 aa), fasta scores;
                     opt: 917 z-score: 1481.6 E(): 0, 59.1% identity in 237 aa
                     overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_630152.1"
                     /transl_table=11
                     /translation="MSDDASTPAAERIPNKGKLAKDLNEVIRYTLWSVFKLKDTLPEDR
                     AGYADEVQELFDQLAAKDVTIRGTYDLSGLRADADLMIWWHAETADQLQEAYNLFRRTK
                     LGRALEPVWSNMALHRPAEFNRSHIPAFLADETPRNYISVYPFVRSYDWYLLPDEDRRR
                     MLADHGKMARGYPDVRANTVASFSLGDYEWILAFEADELHRIVDLMRHLRGSEARRHVR
                     EEIPFYTGRRKDIGELVAGLA"
     misc_feature    complement(1666..1680)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.56"
                     /tool="antismash"
     PFAM_domain     1773..2336
                     /aSDomain="Chlor_dismutase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF06778.15"
                     /db_xref="GO:0016491"
                     /db_xref="GO:0020037"
                     /description="Chlorite dismutase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6042_0697"
                     /evalue="9.00E-75"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /gene_ontologies="GO:0020037: heme binding"
                     /label="SCO6042"
                     /locus_tag="SCO6042"
                     /protein_end="232"
                     /protein_start="44"
                     /score="250.7"
                     /tool="antismash"
                     /translation="RAGYADEVQELFDQLAAKDVTIRGTYDLSGLRADADLMIWWHAET
                     ADQLQEAYNLFRRTKLGRALEPVWSNMALHRPAEFNRSHIPAFLADETPRNYISVYPFV
                     RSYDWYLLPDEDRRRMLADHGKMARGYPDVRANTVASFSLGDYEWILAFEADELHRIVD
                     LMRHLRGSEARRHVREEIPFYTGRR"
     gene            complement(2373..4004)
                     /db_xref="GeneID:1101484"
                     /gene_synonym="SC1B5.03c"
                     /locus_tag="SCO6043"
     CDS             complement(2373..4004)
                     /NRPS_PKS="Domain: Abhydrolase_1 (120-494). E-value:
                     2.8e-19. Score: 61.6. Matches aSDomain:
                     nrpspksdomains_SCO6043_Abhydrolase_1.1"
                     /codon_start=1
                     /db_xref="GeneID:1101484"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC1B5.03c"
                     /locus_tag="SCO6043"
                     /note="SC1B5.03c, probable protease, len: 543 aa;similar to
                     e.g. Streptomyces lividans TR:Q54410 (EMBL:L27466)
                     tripeptidylaminopeptidase (537 aa), fasta scores; opt: 1839
                     z-score: 1633.9 E(): 0, 51.9% identity in 538 aa overlap.
                     Contains possible N-terminal signal sequence"
                     /product="protease"
                     /protein_id="NP_630153.1"
                     /sec_met_domain="PF00561 (E-value: 9e-24, bitscore: 83.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHRAPKGYAMRAAALYSAAGSLLLATLTAAPVRAAPPAGPGPAE
                     ALGTAVAARRAAAAGVDFGRCPQAEELPDGIRCGTVTVPLDYAHPDGKQVRLTVSRVRA
                     THRDPDGGGREVPGQGALLYNPGGPGASGLYFPLVGMVPEWKRIAAAYDLVGYAPRGVA
                     PSAPLSCQDPGDFFKGPRPAPTRPSDAYKKERAAEAEAYARDCAKRGGEALRHYHSLNN
                     ARDLEVVRAALGERRLTFMGASYGTYLGALYAELFPSHVRRMVFDAVVNPDPEQVWYRN
                     NLDQSEAFEDRWDDFKEWVAEHDAVYGLGDTARQVQDSYEEASARLAAEPAGGTVGPAQ
                     FQGAFLTAGYYDDYWPHRAEALSAYLKGDPQPLVDQAGTRTAEGAVRSENSNAVYTAVE
                     CNDAPWPADFEVWDRDNTRLARRAPFETWDNVWTNLPCAYWQGPRQRPLDVRTAPGELP
                     PTLVLAAERDAATPYEGALELRRRLAGSVLVTERDAGTHGIAGGPNACVNGHLEAYLLD
                     GRLPARDTSCAPRPEPEPRQTAAPKA"
     PFAM_domain     complement(2424..2723)
                     /aSDomain="Abhydrolase_4"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08386.13"
                     /description="TAP-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6043_0698"
                     /evalue="6.60E-27"
                     /label="SCO6043"
                     /locus_tag="SCO6043"
                     /protein_end="527"
                     /protein_start="427"
                     /score="93.8"
                     /tool="antismash"
                     /translation="WDNVWTNLPCAYWQGPRQRPLDVRTAPGELPPTLVLAAERDAATP
                     YEGALELRRRLAGSVLVTERDAGTHGIAGGPNACVNGHLEAYLLDGRLPARDTSC"
     aSDomain        complement(2523..3644)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO6043_Abhydrolase_1.1"
                     /evalue="2.80E-19"
                     /label="SCO6043_Abhydrolase_1.1"
                     /locus_tag="SCO6043"
                     /protein_end="494"
                     /protein_start="120"
                     /score="61.6"
                     /tool="antismash"
                     /translation="ALLYNPGGPGASGLYFPLVGMVPEWKRIAAAYDLVGYAPRGVAPS
                     APLSCQDPGDFFKGPRPAPTRPSDAYKKERAAEAEAYARDCAKRGGEALRHYHSLNNAR
                     DLEVVRAALGERRLTFMGASYGTYLGALYAELFPSHVRRMVFDAVVNPDPEQVWYRNNL
                     DQSEAFEDRWDDFKEWVAEHDAVYGLGDTARQVQDSYEEASARLAAEPAGGTVGPAQFQ
                     GAFLTAGYYDDYWPHRAEALSAYLKGDPQPLVDQAGTRTAEGAVRSENSNAVYTAVECN
                     DAPWPADFEVWDRDNTRLARRAPFETWDNVWTNLPCAYWQGPRQRPLDVRTAPGELPPT
                     LVLAAERDAATPYEGALELRRRLAGSVLVTERDA"
     gene            complement(4089..4886)
                     /db_xref="GeneID:1101485"
                     /gene_synonym="SC1B5.04c"
                     /locus_tag="SCO6044"
     CDS             complement(4089..4886)
                     /codon_start=1
                     /db_xref="GeneID:1101485"
                     /gene_synonym="SC1B5.04c"
                     /locus_tag="SCO6044"
                     /note="SC1B5.04c, possible integral membrane protein, len:
                     265 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_630154.1"
                     /transl_table=11
                     /translation="MFWVLFLLSAWAVAGLACLRLCLAAVRAAAVEPGAVVREHTLTLY
                     EAAFLSGGPRRVADLTLVSMARQRRLLLAHTGWATVVDPRGRDDMERSVIGAIGPGGQS
                     RIAPVRAAAAAADAVRSLADRLVGAGLAVPDGGARGIAAGVRRVRVAAVTVCALGLVAL
                     ALPLPATEPRLLIALWFALPLALTLGCLAITRMEIHPYSRWASPAGQRLVGALVQRADG
                     TADDRTFLTSVAVRGVHAIGEPDLRAAFAHREKYAEDHWERRA"
     aSDomain        complement(4167..4862)
                     /aSDomain="TIGR04222"
                     /aSTool="tigrfam"
                     /description="near_uncomplex: TIGR04222 domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO6044_0089"
                     /evalue="1.40E-40"
                     /identifier="TIGR04222"
                     /label="SCO6044"
                     /locus_tag="SCO6044"
                     /protein_end="240"
                     /protein_start="8"
                     /score="137.3"
                     /tool="antismash"
                     /translation="SAWAVAGLACLRLCLAAVRAAAVEPGAVVREHTLTLYEAAFLSGG
                     PRRVADLTLVSMARQRRLLLAHTGWATVVDPRGRDDMERSVIGAIGPGGQSRIAPVRAA
                     AAAADAVRSLADRLVGAGLAVPDGGARGIAAGVRRVRVAAVTVCALGLVALALPLPATE
                     PRLLIALWFALPLALTLGCLAITRMEIHPYSRWASPAGQRLVGALVQRADGTADDRTFL
                     TSVAVRGVHA"
     misc_feature    4948..4965
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 13.84"
                     /tool="antismash"
     gene            complement(5001..6317)
                     /db_xref="GeneID:1101486"
                     /gene_synonym="SC1B5.05c"
                     /locus_tag="SCO6045"
     CDS             complement(5001..6317)
                     /codon_start=1
                     /db_xref="GeneID:1101486"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SC1B5.05c"
                     /locus_tag="SCO6045"
                     /note="SC1B5.05c, unknown, len: 438 aa; slight similarity
                     to hypothetical protein from Haemophilus influenzae
                     YG00_HAEIN P44268 (317 aa), fasta scores; opt: 252 z-score:
                     283.4 E(): 1.5e-08, 26.8% identity in 298 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_630155.1"
                     /sec_met_domain="DUF692 (E-value: 1.7e-103, bitscore:
                     344.4, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRLGTGIGWRPEIADAVEEMPGIEWVEAVSENLCPGHLPDSLLR
                     LRERGVTVVPHGVSLGLGGADRPDAGRLAALAERAEALGSPLVTEHIAFVRAGGALTAS
                     PSLEAGHLLPVPRTRDALDVLCENVRVAQAALPVPLAVENIAALVSWPDEELTEGQFLY
                     ELADRTGVRLLIDVANLHTNHVNRGEDPAEALAGLPLEAIAYVHVAGGFERDGVWHDSH
                     AHPVARPVLDILADLASRVAPPGVLLERDENFPSGDELRGEVEAIRVAVEKGRAAATGT
                     GAAAPTSGTGTDAGSGADDAVRQRLGLAQAALLSALVAGTPVPEGFDRVRLGVQARALA
                     GKRADVVGKVAPELPVILGARYRPAFLAYAQDRPMTGGYRRDALDFVAHVLRTAPGDEG
                     PGVRRELREWWLERSGPVPRSARPGARLARATRRVLLRR"
     PFAM_domain     complement(5508..6302)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05114.16"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6045_0699"
                     /evalue="2.80E-78"
                     /label="SCO6045"
                     /locus_tag="SCO6045"
                     /protein_end="270"
                     /protein_start="5"
                     /score="262.9"
                     /tool="antismash"
                     /translation="TGIGWRPEIADAVEEMPGIEWVEAVSENLCPGHLPDSLLRLRERG
                     VTVVPHGVSLGLGGADRPDAGRLAALAERAEALGSPLVTEHIAFVRAGGALTASPSLEA
                     GHLLPVPRTRDALDVLCENVRVAQAALPVPLAVENIAALVSWPDEELTEGQFLYELADR
                     TGVRLLIDVANLHTNHVNRGEDPAEALAGLPLEAIAYVHVAGGFERDGVWHDSHAHPVA
                     RPVLDILADLASRVAPPGVLLERDENFPSGDELRGEVEAIRVA"
     regulatory      complement(6326..6330)
                     /note="possible RBS upstream of SC1B5.05c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(6461..7210)
                     /db_xref="GeneID:1101487"
                     /gene_synonym="SC1B5.06c"
                     /locus_tag="SCO6046"
     CDS             complement(6461..7210)
                     /codon_start=1
                     /db_xref="GeneID:1101487"
                     /gene_synonym="SC1B5.06c"
                     /locus_tag="SCO6046"
                     /note="SC1B5.06c, unknown, len: 249 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_630156.1"
                     /transl_table=11
                     /translation="MSNDPTTPVPAPVPAPDSPFRPEPGDRDLAPQFVLPLVVRIERAA
                     PPSRTDALETAARAVLVMLGDERSTGDGAWARAVRDWQDARIRKVVRRARGAEWRRAEA
                     LPGITVTGKNAEVRVFPPVPLDGWPKDLARLQVSGTDLDDPEPPVDADPTAPVLWLNPD
                     LDMSAGKAMAQAGHGAQLAWWELSDAERTAWRDAGFPLSVRTADPARWTGLTTGGLPVV
                     RDAGFTEIAPGSCTVVADHPALRRARP"
     PFAM_domain     complement(6482..6742)
                     /aSDomain="PTH2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01981.19"
                     /db_xref="GO:0004045"
                     /description="Peptidyl-tRNA hydrolase PTH2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6046_0700"
                     /evalue="6.90E-07"
                     /gene_ontologies="GO:0004045: aminoacyl-tRNA hydrolase
                     activity"
                     /label="SCO6046"
                     /locus_tag="SCO6046"
                     /protein_end="243"
                     /protein_start="156"
                     /score="29.7"
                     /tool="antismash"
                     /translation="VLWLNPDLDMSAGKAMAQAGHGAQLAWWELSDAERTAWRDAGFPL
                     SVRTADPARWTGLTTGGLPVVRDAGFTEIAPGSCTVVADHPA"
     regulatory      7240..7243
                     /note="possible RBS upstream of SC1B5.07"
                     /regulatory_class="ribosome_binding_site"
     gene            7255..8109
                     /db_xref="GeneID:1101488"
                     /gene_synonym="SC1B5.07"
                     /locus_tag="SCO6047"
     CDS             7255..8109
                     /codon_start=1
                     /db_xref="GeneID:1101488"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /gene_synonym="SC1B5.07"
                     /locus_tag="SCO6047"
                     /note="SC1B5.07, probable ABC-transporter ATP-binding
                     protein, len: 284 aa; similar to many e.g. NOSF_PSEST
                     P19844 pseudomonas stutzeri copper transport atp-binding
                     protein nosF (308 aa), fasta scores; opt: 327 z-score:
                     381.3 E(): 5.2e-14, 30.5% identity in 292 aa overlap.
                     Contains PS00017 ATP/GTP-binding site motif A (P-loop) and
                     Pfam match to entry ABC_tran PF00005, ABC transporters,
                     score 126.83"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_630157.1"
                     /transl_table=11
                     /translation="MRRELRLDGVGRRYGLRGPWVLRGVELGVPPGALVRVEGANGTGK
                     STLLRLLAGIDAPTEGRVTGRPRTAYVPERFPPALPFTAAQYLTHLGTVHGLSRRAAAR
                     AAGHWLERLGAAGYADTRLSRLSKGSSQKVAVAQALLAEPELLVLDEAWTGLDADARGE
                     LERAVAERTAVGGAVVFVDHDPRRLAGVPDAVYAVRDGSLHRRTGPAPVSAGPRVVVRV
                     QGPAGAVLPADVHRTAASAEETGPGSHTLTVPASHSDVLLRTLLTARPPWHVVSVHAPE
                     ERR"
     PFAM_domain     7318..7710
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00005.30"
                     /db_xref="GO:0005524"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6047_0701"
                     /evalue="1.90E-19"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /label="SCO6047"
                     /locus_tag="SCO6047"
                     /protein_end="152"
                     /protein_start="21"
                     /score="70.7"
                     /tool="antismash"
                     /translation="LRGVELGVPPGALVRVEGANGTGKSTLLRLLAGIDAPTEGRVTGR
                     PRTAYVPERFPPALPFTAAQYLTHLGTVHGLSRRAAARAAGHWLERLGAAGYADTRLSR
                     LSKGSSQKVAVAQALLAEPELLVLDEA"
     misc_feature    7348..7857
                     /gene_synonym="SC1B5.07"
                     /locus_tag="SCO6047"
                     /note="Pfam match to entry ABC_tran PF00005, ABC
                     transporters, score 126.83"
     misc_feature    7369..7392
                     /gene_synonym="SC1B5.07"
                     /locus_tag="SCO6047"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     regulatory      8096..8100
                     /gene_synonym="SC1B5.07"
                     /locus_tag="SCO6047"
                     /note="possible RBS upstream of SC1B5.08"
                     /regulatory_class="ribosome_binding_site"
     gene            8106..8780
                     /db_xref="GeneID:1101489"
                     /gene_synonym="SC1B5.08"
                     /locus_tag="SCO6048"
     CDS             8106..8780
                     /codon_start=1
                     /db_xref="GeneID:1101489"
                     /gene_synonym="SC1B5.08"
                     /locus_tag="SCO6048"
                     /note="SC1B5.08, probable integral membrane protein, len:
                     224 aa; contains six possible transmembrane domains."
                     /product="hypothetical protein"
                     /protein_id="NP_630158.1"
                     /transl_table=11
                     /translation="MTALLRYQTALLLRSQRWLPPVVLYAAALGIGVQGGQPVLDSLGW
                     AAAVLLPVAAWLVRICVTGEPPAARECVSAARGPARSHLAAVLVGLAAAVVLGALATVV
                     VTLISDPVSTGHGTRVSPLPAAGAGLLAALVCALLGTAVGALTAWPVLRSPGRAVPALL
                     LAALLALVASGSPARAAVSGLVTGSRSGAVLLPLLPLAGAAVIAAGAIAVACALGSRGP
                     SA"
     gene            complement(8772..9002)
                     /db_xref="GeneID:1101490"
                     /gene_synonym="SC1B5.09c"
                     /locus_tag="SCO6049"
     CDS             complement(8772..9002)
                     /codon_start=1
                     /db_xref="GeneID:1101490"
                     /gene_synonym="SC1B5.09c"
                     /locus_tag="SCO6049"
                     /note="SC1B5.09c, unknown, len: 76 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_630159.1"
                     /transl_table=11
                     /translation="MDSDHGHDREPEPDGAGCEPGGYCLIDAPRPPKADGPPFAECVQC
                     REPTEYPESYKGITLCPVCEWQEAQRTACSG"
     misc_feature    8993..9011
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 17.83"
                     /tool="antismash"
     misc_feature    complement(8994..9012)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.58"
                     /tool="antismash"
     regulatory      complement(9005..9008)
                     /note="possible RBS upstream of SC1B5.09c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(9020..9889)
                     /db_xref="GeneID:1101491"
                     /gene_synonym="SC1B5.10c"
                     /locus_tag="SCO6050"
     CDS             complement(9020..9889)
                     /codon_start=1
                     /db_xref="GeneID:1101491"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC1B5.10c"
                     /locus_tag="SCO6050"
                     /note="SC1B5.10c, probable lipoprotein, len: 289 aa;
                     contains N-terminal signal sequence and appropriately
                     positioned PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site"
                     /product="lipoprotein"
                     /protein_id="NP_630160.1"
                     /transl_table=11
                     /translation="MITLVRRATALCVLGAALAACGTTGAEQAPRPAPSAPDPSPSPSS
                     SARTPTLAPGPAGLTPVFEHGPRTGGTKDGKPVALTFDADMTADQGPRAASGERFDNPG
                     LITALRELKVPATVFMTGRWAEEYPDEARSIGRDPRFEIANHSYSHYAYTDDCYGLPTV
                     PKERMRPDLERAYTAFEKAGVPNPMPYFRFPGGCYDKTALEELSATGVTAVQWDVVSGD
                     AFATDADAVTRQVLDGARPGSVVVMHCTRSAAPVTEEVVRSVVPELRRRGYRFVKVSEL
                     VGAANGHA"
     PFAM_domain     complement(9251..9679)
                     /aSDomain="Polysacc_deac_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01522.24"
                     /db_xref="GO:0005975"
                     /db_xref="GO:0016810"
                     /description="Polysaccharide deacetylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO6050_0702"
                     /evalue="2.30E-31"
                     /gene_ontologies="GO:0005975: carbohydrate metabolic
                     process"
                     /gene_ontologies="GO:0016810: hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds"
                     /label="SCO6050"
                     /locus_tag="SCO6050"
                     /protein_end="213"
                     /protein_start="70"
                     /score="108.5"
                     /tool="antismash"
                     /translation="GTKDGKPVALTFDADMTADQGPRAASGERFDNPGLITALRELKVP
                     ATVFMTGRWAEEYPDEARSIGRDPRFEIANHSYSHYAYTDDCYGLPTVPKERMRPDLER
                     AYTAFEKAGVPNPMPYFRFPGGCYDKTALEELSATGVTA"
     misc_feature    complement(9827..9859)
                     /gene_synonym="SC1B5.10c"
                     /locus_tag="SCO6050"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site"
     misc_feature    complement(9878..9893)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.09"
                     /tool="antismash"
     misc_feature    complement(9998..10120)
                     /gene_synonym="SC1B5.11c"
                     /locus_tag="SCO6051"
                     /note="Pfam match to entry Rieske PF00355, Rieske
                     iron-sulfur protein, score 49.39"
     misc_feature    complement(10049..10066)
                     /gene_synonym="SC1B5.11c"
                     /locus_tag="SCO6051"
                     /note="PS00200 Rieske iron-sulfur protein signature 2"
     misc_feature    complement(10095..10110)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.16"
                     /tool="antismash"
     misc_feature    complement(10100..10120)
                     /gene_synonym="SC1B5.11c"
                     /locus_tag="SCO6051"
                     /note="PS00199 Rieske iron-sulfur protein signature 1"
     misc_feature    complement(10678..10693)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.62"
                     /tool="antismash"
ORIGIN
        1 agcgggcgcc ggacgggcgc ggggcggacg cgcgggtgca cgggtcgtac gcgtacgggc
       61 cgtacgcgta cgggtcgcgc gggacctgcg ggtcggggcc ggggccgtcc ggccccgggg
      121 cggtgtcggt ggcgtctgag acgctggggc catgagcgca agtgagaccc cggcgggcga
      181 gttcccaccg gaacaggaac ccggacacgt agtcgtcgtc ggagccggca tcgccggact
      241 ggccgccgcc caccgcctcc tggaggccgg cgcccgggtg accgtcctgg aggcgtccgg
      301 ccgggtcggc ggcaagctgc tgcccggcga gatcgccggc gtacgcgtcg acctcggtgc
      361 cgagtcgatg ctggcccgcc gccccgaggc cgtcggcctg gcccgcgcgg ccggactcgc
      421 cgaccgcctc cagccgccgt ccaccgcgac cgcctccctg tggacccgcg gcgccctgcg
      481 ccccatgccc aagggccacg tcatgggcgt ccccggcacc gccgccgccc tgtccggcgt
      541 gctctccgag gagggcctcg cccgcatcga gcgcgacgcc gagctgcccc gcaccgaggt
      601 cggcgacgac gtggccgtgg gggagtacgt cgccgcgcgc ctcggccgcg aggtcgtcga
      661 ccgcctcgtc gagccgctcc tgggcggcgt ctacgcgggc gacgcctacc gcatctcgct
      721 ccgctcggcc gtgccgcagc tcttcgaggc cgcccgcacc cacacctcgc tcaccgaggc
      781 ggtccgcgcc ctccagggcc gcacggccac ctcaccgccg agcggcccgg tcttcatggg
      841 catcgagggc ggcatcggca ccctcccgcc cgccgtcgcc gactcggtcc gcgcgcgcgg
      901 cggcgagatc gtcacccagg cgcccgtcac cgagctgcgc cgcaccgcgt ccgacggctg
      961 gcggatcgtc gccggcgacc gggtgctgca cgccggcgcg gtcgtcgtcg ccgtcccggc
     1021 cgggcccgcc gccgagctgc tgcgcgccga ggcgcccgcc gccgcggccg agctgtccgc
     1081 ggtggagtac gcctcgatgg ccctggtcac cctcgcctac cgccgctcgg aggccgccgc
     1141 gctccccgag ggcagcggct tcctcgtacc gccggtcgac gggcacacca tcaaggcgtc
     1201 caccttcgcc tcccgcaagt ggggctggat cgccgacgag gacccggacc tggtcgtcct
     1261 gcgcacctcg gtgggccggt acggcgacac ggagatcctc ggccgcgacg acgcgggact
     1321 cgtcgccgtc tcccggcacg acctcgcgga ggccaccggc ctgaccgccg cgcccgtcgc
     1381 cacccgcgtc acccgttggc aggacggcct gccgcagtac cccgtcggcc accacgcgcg
     1441 cgtggcccgc gtccgcgagc acgtcgcgaa gctcccgggc ctcgcggtgt gcggcgcggc
     1501 gtacgacggc gtcggcatcc cggccagcat cgcgagcgcg tacgcggccg ccgaccagat
     1561 ccggggcgac ctcggcggtg tggaggagct cacggcccac ccggtgcaga gcctgcacgg
     1621 cggagcggga gaatagggcc atgagtgacg acgcctccac ccccgcggcc gagcgcatcc
     1681 cgaacaaggg caagctggcc aaggacctca acgaggtcat ccgctacacc ctctggtccg
     1741 tcttcaagct caaggacacc ctccccgagg accgcgccgg gtacgccgac gaggtccagg
     1801 agctgttcga ccagctcgcc gcgaaggacg tgacgatccg cggcacctac gacctgtccg
     1861 ggctgcgcgc ggacgccgac ctgatgatct ggtggcacgc cgagaccgcc gaccagctcc
     1921 aggaggcgta caacctcttc cgccgcacga agctcgggcg ggcgctggag ccggtctggt
     1981 cgaacatggc gctgcaccgc cccgccgagt tcaaccgctc gcacatcccg gccttcctgg
     2041 ccgacgagac gccgcggaac tacatcagcg tctacccgtt cgtgcgctcg tacgactggt
     2101 acctgctgcc cgacgaggac cgccgccgca tgctcgccga ccacggcaag atggcccgcg
     2161 gctacccgga cgtgcgcgcc aacacggtcg cctccttctc gctgggcgac tacgagtgga
     2221 tcctcgcctt cgaggccgac gagctgcacc gcatcgtcga cctcatgcgc cacctgcgcg
     2281 gctccgaggc gcgtcgccac gtccgcgagg agatcccgtt ctacaccggg cgccgcaagg
     2341 acatcggcga gctggtcgcc gggctcgcct agtcaggcct tcggtgccgc ggtctgccgt
     2401 ggctccggtt ccgggcgcgg ggcgcacgac gtgtcccgcg ccgggaggcg gccgtccagc
     2461 aggtacgcct ccaggtggcc gttgacgcag gcgttcggcc cccccgcgat gccgtgcgtc
     2521 ccggcgtccc gctcggtcac cagcaccgag cccgccagcc gccgccgcag ctccagcgca
     2581 ccctcgtacg gtgtcgccgc gtcccgttcc gcggccagga ccagcgtcgg cggcagctcg
     2641 cccggcgcgg tgcgcacgtc gagcggccgc tgccggggcc cctgccagta ggcgcacggc
     2701 aggttggtcc acacgttgtc ccaggtctcg aacggcgccc ggcgggccag ccgggtgttg
     2761 tcccggtccc agacctcgaa gtcggccggc cagggcgcgt cgttgcactc gacggccgtg
     2821 tacacggcgt tggagttctc cgaccgcacc gcgccctccg cggtccgggt gcccgcctgg
     2881 tcgaccagcg gctgcggatc gcccttcagg tacgccgaca gcgcctcggc gcggtgcggc
     2941 cagtagtcgt cgtagtaccc ggccgtcagg aacgccccct ggaactgcgc gggccccacc
     3001 gtgccgcccg ccggctccgc cgccagccgc gcgctcgcct cctcgtagct gtcctgcacc
     3061 tgcctcgccg tgtccccgag cccgtacacg gcgtcgtgct cggcgaccca ctccttgaag
     3121 tcgtcccagc ggtcctcgaa ggcctccgac tggtcgaggt tgttgcggta ccagacctgc
     3181 tcgggatccg gattcaccac cgcgtcgaac accatccgcc gcacgtgcga ggggaacagc
     3241 tcggcgtaca gcgcgccgag gtaggtgccg taggacgcgc ccatgaacgt gagccgccgc
     3301 tcgcccagcg cggcgcggac gacctccagg tcccgggcgt tgttgagcga gtggtagtgc
     3361 cgcagcgcct ccccgccccg tttcgcgcag tcgcgcgcgt acgcctcggc ctccgcggcg
     3421 cgctccttct tgtacgcgtc cgagggccgc gtcggcgccg gccgcggccc cttgaagaag
     3481 tccccggggt cctggcagga cagcggcgcg gagggcgcga ccccgcgcgg ggcgtacccg
     3541 acgaggtcgt aggcggcggc gatgcgcttc cactcgggca ccatgcccac cagcgggaag
     3601 tacagcccgg aggcgccggg gccgcccggg ttgtagagga gggcgccctg gccggggacc
     3661 tcgcgcccgc cgccgtccgg gtcccggtgg gtggcccgca cccggctgac ggtgagccgg
     3721 acctgcttgc cgtccgggtg ggcgtagtcc agcggcacgg tcacggtgcc gcagcggatg
     3781 ccgtccggca gctcctccgc ctgcgggcac ctgccgaagt ccaccccggc cgccgccgcg
     3841 cgccgggccg ccacggcggt gccgagcgcc tcggccggtc cgggtccggc cggcggcgcc
     3901 gcccggacgg gggcggcggt gagggtggcc agcagcaagg acccggcggc cgagtagagg
     3961 gcggcagctc gcatcgcgta tcccttcggt gcacggtgtg acacaaggga tgtttggtgc
     4021 ggcggccgga cggggcaagc accgcccgcg ggtgtcggcg ccgagtgcct ccgtacgccc
     4081 cccgagcgtc aggcccggcg ctcccagtgg tcctcggcgt acttctcgcg gtgggcgaag
     4141 gcggcacgca ggtccggttc gccgatcgcg tgcacgccgc gcacggcgac cgaggtgagg
     4201 aaggtccggt cgtccgccgt gccgtcggcc cgctgcacga gggcgccgac cagccgttgc
     4261 ccggcggggg aggcccagcg cgagtacggg tggatctcca tccgcgtgat ggccaggcag
     4321 cccagggtga gggcgagcgg cagcgcgaac cagagggcga tcaggaggcg cggttcggtg
     4381 gcgggcagcg gcagcgccag ggcgaccagg ccgagcgcgc acaccgtcac cgcggcgacc
     4441 cgcacccggc gcaccccggc cgcgatcccc cgggcaccgc cgtcgggcac ggcgaggccc
     4501 gcgccgacca gccggtcggc caggctccgt accgcgtcgg cggcggccgc ggcggcccgg
     4561 accggcgcta tccgggactg tccgcccgga cctatcgccc ctatcaccga ccgctccatg
     4621 tcgtcccgcc cgcgcgggtc cacgacggtc gcccatccgg tgtgcgcgag cagcagccgg
     4681 cgctggcgcg ccatcgagac cagcgtcagg tcggccaccc gccgcgggcc gccggacagg
     4741 aacgccgcct cgtacagcgt cagcgtgtgc tcacggacga cggcgcccgg ttccacggcc
     4801 gccgcgcgta cggcggccag gcacagccgc aggcacgcga ggccggcgac ggcccaggcc
     4861 gacaggagga aaaggaccca gaacatgccg tacttctatg ccaaaggctt tcgccggcgc
     4921 catgcccttt tcacattccg ggacgcagtg ttgtgggtat gtgacgttcc gctcggcgat
     4981 gtcccccgac gtcccccggt tcagcggcgc agcagaacac gcctggtcgc acgggccagc
     5041 cgggccccgg gacgcgccga ccgcggcacc ggtcccgacc gctccagcca ccactcccgc
     5101 aactcccgcc gcacgcccgg gccctcgtcc ccgggcgccg tccgcagcac gtgtgcgacg
     5161 aagtcgaggg cgtcccgccg gtagccgccg gtcatcggac ggtcctgcgc gtaggcgagg
     5221 aaggcaggcc ggtaccgcgc gcccaggatc accggcagct cgggcgcgac cttgccgacc
     5281 acgtcggccc gcttgccggc cagcgcccgc gcctgcaccc ccagccgcac ccggtcgaac
     5341 ccctcgggca ccggcgtccc cgcgaccagc gcggacagca gcgcggcctg cgccagcccg
     5401 agccgctgcc gtacggcgtc gtcggcgccg gagcccgcgt cggtaccggt gcccgaggtg
     5461 ggggcggccg ctccggtccc ggtggccgcc gcccgcccct tctccacggc gacgcggatc
     5521 gcctccacct caccccgcag ctcgtcgccg gaggggaagt tctcgtcgcg ctccagcagc
     5581 acgcccggcg gcgcgacgcg cgaggcgagg tcggccagga tgtccagcac cggccgcgcg
     5641 acggggtggg cgtggctgtc gtgccagacg ccgtcccgct cgaagccgcc cgcgacatgg
     5701 acgtaggcga tggcctccag gggcagcccg gcgagcgcct cggcagggtc ctcaccccgg
     5761 ttgacgtggt tggtgtgcag gttcgccacg tcgatcagca gccgcacgcc ggtccggtcg
     5821 gccagctcgt acaggaactg cccctccgtc agctcctcgt ccggccacga gacgagcgcg
     5881 gcgatgttct ccacggcgag cggcacgggc agcgcggcct gcgcgacgcg cacgttctcg
     5941 cacagcacgt cgagggcgtc gcgcgtgcgc ggcacgggca gcaggtgccc cgcctccagc
     6001 gacggcgacg cggtcagcgc cccgcccgcg cgcacgaacg cgatgtgctc ggtgaccagc
     6061 ggcgacccga gcgcctcggc ccgctcggcc agcgccgcca gccgtcccgc gtccggtcgg
     6121 tccgcgccgc cgagccccag cgagaccccg tgcggtacga cggtcacgcc gcgctcgcgc
     6181 agccgcagca gcgagtcggg cagatgcccg ggacacaggt tctcggacac ggcctcgacc
     6241 cactcgatgc cgggcatctc ctcgacggcg tccgcgatct ccggccgcca tccgatgccg
     6301 gtgcccagtc gtcgcatggc cggtccctcc ctccgcgtcg tcatgaccgg ggtatcgccc
     6361 gcgcgagggg gcccgaaccc cgcggagggc gccttcagag gaacatttga ggttcgaggt
     6421 ccgcgggccg ccgcgggccc cggccggttc gcctccgcgc ctacgggcgc gcccgccgca
     6481 gcgccggatg gtccgccacc acggtgcacg aacccggcgc gatctccgtg aacccggcgt
     6541 cccgcaccac cggcaggccg ccggtggtga ggccggtcca gcgggccggg tccgcggtgc
     6601 gcaccgacag cgggaagccc gcgtcgcgcc aggccgtccg ctcggcgtcg gacagctccc
     6661 accaggcgag ctgcgcaccg tggcccgcct gggccatcgc cttgcccgcc gacatgtcca
     6721 ggtcggggtt gagccagagc accggcgcgg tggggtcggc gtcgaccggc ggctcggggt
     6781 cgtcgaggtc ggtgccggag acctggaggc gggccaggtc cttgggccag ccgtccaacg
     6841 ggaccggcgg gaagacgcgt acctcggcgt tcttgccggt gaccgtgatg cccggcagcg
     6901 cctcggcccg ccgccactcc gcgccgcggg cccgccgcac gaccttgcgg atgcgggcgt
     6961 cctgccagtc ccgcaccgcc cgcgcccacg cgccgtcacc ggtggaccgc tcgtcgccga
     7021 gcatcaccag caccgcccgg gccgcggtct ccagcgcgtc ggtgcgggac ggcggtgccg
     7081 cccgctcgat gcgcaccacg agcggcagca cgaactgcgg tgcgaggtcg cggtcgccgg
     7141 gctcgggtcg gaaggggctg tcgggggcgg gaacgggcgc ggggacgggt gtcgtcgggt
     7201 cgttgctcac gccctacagt ctgccaaccc gcgggcctgg gagagtatgg ccccatgcga
     7261 cgcgagctac ggctggacgg tgtgggccgc cgctacggtc tgcgcggtcc gtgggtgctg
     7321 cgcggggtcg agctgggcgt gccgcccggc gccctcgtcc gcgtcgaggg cgccaacggc
     7381 accggcaagt cgaccctgct gcgcctgctc gccgggatcg acgcccccac cgagggccgg
     7441 gtcaccggcc gcccgcgcac cgcctacgtc cccgaacgct tcccgcccgc cctgcccttc
     7501 accgccgccc agtacctcac ccacctcggt accgtccacg gcctgtcccg ccgggcggcg
     7561 gcccgtgccg ccgggcactg gctggagcgg ctgggggccg ccgggtacgc cgacacgcgg
     7621 ctctcccggc tgtccaaggg cagcagtcag aaggtggcgg tggcgcaggc cctgctcgcc
     7681 gagccggagc tgctcgtgct cgacgaggcc tggaccgggc tggacgcgga cgcgcggggc
     7741 gagttggagc gggcggtcgc cgaacggacc gcggtcggcg gcgccgtggt cttcgtcgat
     7801 cacgatccgc gccgcctggc aggcgtgccc gacgccgtgt acgccgtgcg cgacggcagc
     7861 ctgcaccgcc gtaccggacc ggccccggtg tccgcggggc cgcgggtcgt cgtgcgggtg
     7921 caggggccgg ccggtgccgt cctccccgcc gacgtgcacc gcacggccgc ctcggccgag
     7981 gagaccggcc ccggatccca cacgctcacc gttcccgcct cgcactccga cgtcctgctg
     8041 cgcacgctcc tgaccgcccg gccgccctgg cacgtggtga gcgtgcacgc ccccgaggag
     8101 cgccgatgac cgccctgctg cgctaccaga ccgcgctcct gctgcgctct cagcgctggc
     8161 tgccgcccgt cgtcctgtac gccgccgcgc tcggcatcgg cgtgcagggc gggcagccgg
     8221 tgctcgactc gctgggctgg gcggcggccg tgctgctgcc ggtcgcggcc tggctggtgc
     8281 ggatctgcgt cacgggcgag ccgcccgccg cgcgggagtg cgtgtcggcg gcacggggtc
     8341 ccgcgcggtc ccacctcgcc gccgtactgg tggggctggc cgccgccgtc gtcctgggcg
     8401 ccctcgcgac cgtcgtcgtg acgctgatca gcgaccccgt cagcaccggt cacggaacgc
     8461 gcgtgtcccc gcttccggcg gccggtgcgg ggctgctcgc cgcgctggtg tgcgccctgc
     8521 tcggcaccgc cgtcggcgcg ctcaccgcct ggccggtgct gcgctcgccc ggccgcgcgg
     8581 tccccgccct gctgctggcg gccctgctgg cgctcgtggc gtcggggtcc ccggcgcggg
     8641 cggcggtcag cggcctggtc accgggtcca ggtcgggtgc ggtcctgctg ccgctgctgc
     8701 cgctggccgg ggcggcggtc atcgccgcgg gcgcgatcgc cgtggcctgt gcgctcggct
     8761 cgcgcggacc gtcagcctga gcaggcggtg cgctgggcct cctgccactc gcagaccggg
     8821 cagagcgtga tgcccttgta cgactccggg tactccgtcg gctcccggca ctgcacgcac
     8881 tccgcgaacg gcggaccgtc ggccttcggc ggccggggcg cgtcgatcag gcagtagccg
     8941 ccgggctcgc agccggcgcc gtccggctcc ggttcgcggt cgtggccgtg gtcgctgtcc
     9001 atgtctccag cctagggcgt caggcgtgcc cgttcgcggc gccgaccagc tccgagacct
     9061 tcacgaagcg gtacccccgg cggcgcagct ccggcaccac cgaccgcacc acctcctcgg
     9121 tcaccggggc ggcgctgcgc gtgcagtgca tgacgacgac cgaacccggc cgcgccccgt
     9181 cgagcacctg ccgggtcacc gcgtcggcgt ccgtcgcgaa ggcgtccccg ctcaccacgt
     9241 cccactgcac ggcggtgacc ccggtggccg acaactcctc gagggccgtc ttgtcgtagc
     9301 agccgccggg gaagcggaag tacggcatcg ggttcggcac cccggccttc tcgaacgccg
     9361 tgtacgcccg ctccaggtcc gggcgcatgc gctccttggg cacggtgggc aggccgtagc
     9421 agtcgtcggt gtacgcgtag tggctgtagg agtggttggc gatctcgaac cgcgggtccc
     9481 ggccgatgga gcgggcctcg tcggggtact cctccgccca gcggccggtc atgaacaccg
     9541 tggccggcac cttcagctcc cgcagcgccg tgatcaggcc cgggttgtcg aaccgctcgc
     9601 cggacgccgc ccgcggcccc tggtcggcgg tcatgtcggc gtcgaaggtg agggcgaccg
     9661 gcttgccgtc cttggtgccg ccggtgcgcg ggccgtgctc gaagacgggc gtcaggcccg
     9721 cggggccggg ggcgagggtg ggcgtccggg cggacgagga gggggagggg gacgggtcgg
     9781 gggccgaggg cgccggacgg ggggcctgct cggccccggt ggttccgcag gcggcgaggg
     9841 cggcgcccag gacacagagc gcggtggcac gtcgtacgag agtgatcacc gtacgaacgt
     9901 aggagtggga tggtcgtttc gtatgaccgt gagtggtgac gtgccgcccc ggtcacccgc
     9961 ccggctcagg ccccgggcgt cagatctccc gccgctccag cggcttggtc gccgggccct
    10021 ccagcaccct gccgtccgtg ccgaagcggg agccgtggca ggggcactcc caggcgcgtt
    10081 cggccgcgtt gaagtcgacc aggcagccca ggtgggtgca gcgcggcgag acggcgtgca
    10141 gggcgccctc ctcgtcccgg tagaccgcga gccggccgcc gcccgcccgg acgaccgcgc
    10201 cctcgcccgg cggcagcgcc tccaccggcg gggtgggccg cagccggtcg ccgacgaagt
    10261 gccgggccac ctcggcctgc gtcttgagca gcgcgggcgc ctcccgcacc gccgtgcgca
    10321 gccggcgcgg gtcgtacagc ccgctccacg cgcactcctc gccggtgatc tgcgcggtga
    10381 gcagccggcc cgccatcatg ccgccgctca gcccccagcc gccgaagccg gtggcgacgt
    10441 acgtgtggtg cgcgcccggg tgcagcgggc ccaccatcgg cacggtgtcg gtggggtcga
    10501 tgtcctgggt ggcccaggcg tgggtgcgct cgacgcctgg gaagtgctcg tccgcccagg
    10561 cggcgagggt ctcgaagcgc tcgcgggtgt cgcccgtgcc gggggtgaag tgctcgccgg
    10621 tgacgacgag caggcggcgg cccgcgtcgg ccaggggggc cgtgcgcacc gagcgggtgt
    10681 tctcctccgg cgtgatgtac atgccgtcga cgtcgcggtc cgcctcgacg gtcccggcga
    10741 cgaccagttc gcggcgcggg gagaggcggg cgaagagcag ggcccggtcg aagatcggat
    10801 agtgcgtggc caccacgacg tcccgggcgg tgaccgtcgc ccccgcctcc gtccgcaccc
    10861 ggcacggctc gccctcgtcc agaccctgga cggtggtgcc ctcgaagatc cgcccgccgc
    10921 gcgcctccag gtccgcggcg agggccagca ggtacttgac ggggtggaac tgggcctgtc
    10981 cggtcacctt cacggcgccc gccaccggga acggcagccc ggtctccgtc acgaacgacg
    11041 cgggcagccc cgcctcctcg gccgcggccg cctcggcgcg cagctcgtcc acgcggcccg
    11101 ggtcgcggac gtacgtgtag gcgtcccggg tctcccagtc gcagtcgatg cccagctcgg
    11161 cgacgatccc ggcggcgtgc tcgatcgcct cggactgcga gcgggcgtac agccgggcgc
    11221 cctcggggcc gcgggtgcgg cgcagcctgt cgtagaccag ggtgtgcagg acggtcagct
    11281 tggcgctggt gtacccggtg accccggcgg cgacccg
//
