LOCUS       NC_003888              72543 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    .
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2023-11-22 14:16:39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 5751944
            Orig. end    :: 5824487
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..72543
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[35000:37543]"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_product_classes="pentangular polyphenol"
                     /t2pks_product_classes="tetracenomycin"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      35001..37543
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_product_classes="pentangular polyphenol"
                     /t2pks_product_classes="tetracenomycin"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     cand_cluster    1..72543
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..72543
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T2PKS"
                     /region_number="13"
                     /rules="(t2ks and t2clf)"
                     /tool="antismash"
     misc_feature    complement(557..1237)
                     /gene="kgd"
                     /gene_synonym="SCCB12.05c"
                     /locus_tag="SCO5281"
                     /note="Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid
                     dehydrogenases acyltransferase (catalytic domain), score
                     42.90, E-value 5.8e-12"
     misc_feature    complement(1209..1220)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(1271..1534)
                     /gene="kgd"
                     /gene_synonym="SCCB12.05c"
                     /locus_tag="SCO5281"
                     /note="proline and alanine rich region. High G+C content:
                     88.63%"
     misc_feature    complement(1830..1840)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            complement(2005..3132)
                     /db_xref="GeneID:1100723"
                     /gene_synonym="SCCB12.06c"
                     /locus_tag="SCO5282"
     CDS             complement(2005..3132)
                     /codon_start=1
                     /db_xref="GeneID:1100723"
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 181.3; E-value: 7e-55)"
                     /gene_kind="regulatory"
                     /gene_synonym="SCCB12.06c"
                     /locus_tag="SCO5282"
                     /note="SCCB12.06c, possible two-component system sensor
                     kinase, len: 375 aa; similar to SW:AFQ2_STRCO (EMBL:D10654)
                     Streptomyces coelicolor sensor protein AfsQ2, 535 aa; fasta
                     scores: opt: 344 z-score: 382.3 E(): 7.9e-14; 32.5%
                     identity in 335 aa overlap. Contains Pfam matches to
                     entries PF00672 DUF5, HAMP domain and PF00512 signal,
                     Histidine kinase. Also contains possible hydrophobic
                     membrane spanning regions"
                     /product="two-component system sensor kinase"
                     /protein_id="NP_629427.1"
                     /transl_table=11
                     /translation="MSSRGREAARRNPGPRTTGEPWGGVRPFSIKTKLGALVVTSVLIT
                     TGLSVIAVHTKTELRFITVFSMIATLLITQFVAHSLTAPLDEMNAVARSISHGDYTRRV
                     RENRRDELGDLAVTINRMADDLEAQDLQRKELVANVSHELRTPIAGLRAVLENIVDGVT
                     EADPETMRTALGQTERLGRLVETLLDLSRLDNGVIPLRKRRFEVWPYLSGVLKEANMVA
                     SARAGIASGSGSHSRTDVHLALDVFPPELTAHADPERIHQVVANLIDNAVKHSPPHGRV
                     TVRARRGELPESLELEVLDEGPGIPRSEWRRVFERFNRGSVSRPHGPGSDGGTGLGLAI
                     ARWAVDLHGGRIGVAESERGCRILITLPGLPSTSG"
     PFAM_domain     complement(2029..2367)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02518.29"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5282_0481"
                     /evalue="1.50E-22"
                     /label="SCO5282"
                     /locus_tag="SCO5282"
                     /protein_end="368"
                     /protein_start="255"
                     /score="80.3"
                     /tool="antismash"
                     /translation="DPERIHQVVANLIDNAVKHSPPHGRVTVRARRGELPESLELEVLD
                     EGPGIPRSEWRRVFERFNRGSVSRPHGPGSDGGTGLGLAIARWAVDLHGGRIGVAESER
                     GCRILITLP"
     misc_feature    complement(2029..2709)
                     /gene_synonym="SCCB12.06c"
                     /locus_tag="SCO5282"
                     /note="Pfam match to entry PF00512 signal, Histidine
                     kinase, score 173.10, E-value 4.7e-48"
     PFAM_domain     complement(2545..2736)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00512.28"
                     /db_xref="GO:0000155"
                     /db_xref="GO:0007165"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5282_0480"
                     /evalue="1.80E-15"
                     /gene_ontologies="GO:0000155: phosphorelay sensor kinase
                     activity"
                     /gene_ontologies="GO:0007165: signal transduction"
                     /label="SCO5282"
                     /locus_tag="SCO5282"
                     /protein_end="196"
                     /protein_start="132"
                     /score="56.8"
                     /tool="antismash"
                     /translation="RKELVANVSHELRTPIAGLRAVLENIVDGVTEADPETMRTALGQT
                     ERLGRLVETLLDLSRLDNG"
     misc_feature    complement(2749..2958)
                     /gene_synonym="SCCB12.06c"
                     /locus_tag="SCO5282"
                     /note="Pfam match to entry PF00672 DUF5, HAMP domain, score
                     72.10, E-value 1.2e-17"
     PFAM_domain     complement(2752..2907)
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00672.28"
                     /db_xref="GO:0007165"
                     /db_xref="GO:0016020"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5282_0479"
                     /evalue="4.80E-15"
                     /gene_ontologies="GO:0007165: signal transduction"
                     /gene_ontologies="GO:0016020: membrane"
                     /label="SCO5282"
                     /locus_tag="SCO5282"
                     /protein_end="127"
                     /protein_start="75"
                     /score="55.8"
                     /tool="antismash"
                     /translation="FVAHSLTAPLDEMNAVARSISHGDYTRRVRENRRDELGDLAVTIN
                     RMADDLE"
     gene            complement(3129..3863)
                     /db_xref="GeneID:1100724"
                     /gene_synonym="SCCB12.07c"
                     /locus_tag="SCO5283"
     CDS             complement(3129..3863)
                     /codon_start=1
                     /db_xref="GeneID:1100724"
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 207.5; E-value: 3.3e-63)"
                     /gene_kind="regulatory"
                     /gene_synonym="SCCB12.07c"
                     /locus_tag="SCO5283"
                     /note="SCCB12.07c, possible two-component system response
                     regulator, len: 244 aa; similar to TR:Q9ZEP4
                     (EMBL:AJ131213) Streptomyces coelicolor response regulator
                     CseB or SCE94.09, 234 aa; fasta scores: opt: 632 z-score:
                     771.1 E(): 0; 44.3% identity in 230 aa overlap and to
                     SW:RESD_BACSU (EMBL:L09228), 240 aa; fasta scores: opt: 573
                     z-score: 699.9 E(): 1.6e-31; 39.7% identity in 234 aa
                     overlap. Contains Pfam matches to entries PF00072
                     response_reg, Response regulator receiver domain and
                     PF00486 trans_reg_C, Transcriptional regulatory protein, C
                     terminal"
                     /product="two-component system response regulator"
                     /protein_id="NP_629428.1"
                     /transl_table=11
                     /translation="MEQTQTSHNGTATQGAQRRVLVVEDDQTIVDAIATRLRAEGFLVQ
                     TAGDGPSAVDTAEAWQPDLLILDIMLPGFDGLEVCRRVQAQRPVPVLMLTARDDETDML
                     VGLGVGADDYMTKPFSMRELAARVHVLLRRVERAVVAASTPRSGILRLGELEIDHAQRR
                     VRVRSEDVHLTPTEFDLLVCLANTPRAVLSREQLLAEVWDWADASGTRTVDSHIKALRR
                     KIGAERIRTVHGVGYALETPTP"
     PFAM_domain     complement(3147..3359)
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00486.31"
                     /db_xref="GO:0000160"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0006355"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5283_0483"
                     /evalue="1.50E-23"
                     /gene_ontologies="GO:0000160: phosphorelay signal
                     transduction system"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO5283"
                     /locus_tag="SCO5283"
                     /protein_end="239"
                     /protein_start="168"
                     /score="82.8"
                     /tool="antismash"
                     /translation="EDVHLTPTEFDLLVCLANTPRAVLSREQLLAEVWDWADASGTRTV
                     DSHIKALRRKIGAERIRTVHGVGYAL"
     misc_feature    complement(3156..3359)
                     /gene_synonym="SCCB12.07c"
                     /locus_tag="SCO5283"
                     /note="Pfam match to entry PF00486 trans_reg_C,
                     Transcriptional regulatory protein, C terminal, score
                     107.00, E-value 1.1e-30"
     PFAM_domain     complement(3480..3806)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00072.27"
                     /db_xref="GO:0000160"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5283_0482"
                     /evalue="1.30E-26"
                     /gene_ontologies="GO:0000160: phosphorelay signal
                     transduction system"
                     /label="SCO5283"
                     /locus_tag="SCO5283"
                     /protein_end="128"
                     /protein_start="19"
                     /score="93.1"
                     /tool="antismash"
                     /translation="VLVVEDDQTIVDAIATRLRAEGFLVQTAGDGPSAVDTAEAWQPDL
                     LILDIMLPGFDGLEVCRRVQAQRPVPVLMLTARDDETDMLVGLGVGADDYMTKPFSMRE
                     LAARV"
     misc_feature    complement(3480..3812)
                     /gene_synonym="SCCB12.07c"
                     /locus_tag="SCO5283"
                     /note="Pfam match to entry PF00072 response_reg, Response
                     regulator receiver domain, score 122.60, E-value 7.2e-33"
     gene            complement(3977..4684)
                     /db_xref="GeneID:1100725"
                     /gene_synonym="SCCB12.08c"
                     /locus_tag="SCO5284"
     CDS             complement(3977..4684)
                     /codon_start=1
                     /db_xref="GeneID:1100725"
                     /gene_synonym="SCCB12.08c"
                     /locus_tag="SCO5284"
                     /note="SCCB12.08c, hypothetical protein, len: 235 aa;
                     similar to TR:Q9RVH7 (EMBL:AE001956) Deinococcus
                     radiodurans hypothetical 24.5 kDa protein DR1052, 230 aa;
                     fasta scores: opt: 403 z-score: 466.7 E(): 1.6e-18; 38.5%
                     identity in 218 aa overlap and to SW:SPEE_ECOLI
                     (EMBL:J02804) Escherichia coli spermidine synthase (EC
                     2.5.1.16) SpeE, 287 aa; fasta scores: opt: 173 z-score:
                     204.7 E(): 0.00063; 31.9% identity in 119 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_629429.1"
                     /transl_table=11
                     /translation="MPLTTHDSPEAAEAPEVLDRREGPYGEVVLRRHGTLLQIIANGCF
                     LMDTSDGRSERRLVDAAADALAASGGRTAPHLLIGGLGVGFSLAHAAADPRWGRIAVVE
                     REGAIIDWHRTGPLAALSADALADPRAEIVEADLVEYVNETSDTYDALCLDIDNGPGWT
                     VTEGNDGLYAPSGLAGCARLLRPGGVLAVWSAQPSPEFEETLRNAGFQQVRTEEIPVAR
                     GVPDVVHIGVGPG"
     regulatory      complement(4692..4698)
                     /regulatory_class="ribosome_binding_site"
     regulatory      4856..4859
                     /regulatory_class="ribosome_binding_site"
     gene            4863..7286
                     /db_xref="GeneID:1100726"
                     /gene_synonym="lon; SCCB12.09"
                     /locus_tag="SCO5285"
     CDS             4863..7286
                     /codon_start=1
                     /db_xref="GeneID:1100726"
                     /gene_synonym="lon; SCCB12.09"
                     /locus_tag="SCO5285"
                     /note="SCCB12.09, lon, ATP-dependent protease, len: 807 aa;
                     similar to SW:LON_MYCSM (EMBL:AF030688) Mycobacterium
                     smegmatis ATP-dependent protease LA (EC 3.4.21.53) Lon, 779
                     aa; fasta scores: opt: 2550 z-score: 2489.6 E(): 0; 64.7%
                     identity in 785 aa overlap. Contains Pfam matches to
                     entries PF02190 LON, ATP-dependent protease La (LON) domain
                     and PF00004 AAA, ATPases associated with various cellular
                     activities (AAA) and matches to Prosite entries PS00017
                     ATP/GTP-binding site motif A (P-loop) and PS01046
                     ATP-dependent serine proteases, lon family, serine active
                     site"
                     /product="ATP-dependent protease"
                     /protein_id="NP_629430.1"
                     /transl_table=11
                     /translation="MAAESAAFTPLTLPVLPLDDEVVLPGMVVPLDLSDAEVRAAVEAA
                     QAAARSEPGKPRVLLVPRIDGTHAATGVLGTVEQVGRLADGDPGALIRGRGRVRIGAGT
                     TGPGAALWVEGTRVDETVPDPLPGQVAELVKEYKALATAWLRKRGAWQVVDRVQAIDDV
                     SALADNSGYSPFLTTEQKVELLETTDPVARLKIATQQLRDHLAEQDVAETIAKDVQEGV
                     DKQQREFLLRRQLEAVRKELREINGEQEGEESDDYRARVEAADLPEKVREAALKEVDKL
                     ERSSDQSPEGSWIRTWLDTVLEMPWSERTEDAYDIQGAQAVLDAEHAGLEDVKERITEY
                     LAVRKRRGDRGLGVVGGRRGGAVLALVGPPGVGKTSLGESVAHAMGRKFVRVALGGVRD
                     EAEIRGHRRTYVGALPGRIVRAIKEAGSMNPVVLLDEIDKVGSDFRGDPAAALLEVLDP
                     AQNHTFRDHYLEVELDLSDVVFLATANVLEAIPEALLDRMELVRLDGYTEDEKVVIARD
                     HLLPRQLERAGLDDDEVTVDEGALRKLAGEYTREAGVRTLERSIARLLRKVAAQHELGE
                     RELPFTVTEGDLRSLIGRPHHVPESAQDPAERRTAVPGVATGLAVTGAGGDVLYVEASL
                     ADPETGAAGLTLTGQLGDVMKESAQIALSFLRSHGAELELPVGDLKDRGAHIHFPAGAV
                     PKDGPSAGVTMTTALASLLSGRLVRTDVAMTGEVSLTGRVLPIGGVKQKLLAAHRAGIT
                     TVIIPKRNEPDLDDVPAQVLDKLDVHAVTDVRQVLELALAPATNGAEREVPVAA"
     PFAM_domain     4896..5468
                     /aSDomain="LON_substr_bdg"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02190.19"
                     /description="ATP-dependent protease La (LON)
                     substrate-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5285_0484"
                     /evalue="5.20E-16"
                     /label="SCO5285"
                     /locus_tag="SCO5285"
                     /protein_end="202"
                     /protein_start="11"
                     /score="59.2"
                     /tool="antismash"
                     /translation="TLPVLPLDDEVVLPGMVVPLDLSDAEVRAAVEAAQAAARSEPGKP
                     RVLLVPRIDGTHAATGVLGTVEQVGRLADGDPGALIRGRGRVRIGAGTTGPGAALWVEG
                     TRVDETVPDPLPGQVAELVKEYKALATAWLRKRGAWQVVDRVQAIDDVSALADNSGYSP
                     FLTTEQKVELLETTDPVARLKIATQQLR"
     misc_feature    4896..5471
                     /gene_synonym="lon; SCCB12.09"
                     /locus_tag="SCO5285"
                     /note="Pfam match to entry PF02190 LON, ATP-dependent
                     protease La (LON) domain, score -18.10, E-value 0.00014"
     aSDomain        4902..7238
                     /aSDomain="TIGR00763"
                     /aSTool="tigrfam"
                     /description="lon: endopeptidase La"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5285_0062"
                     /evalue="1.60E-236"
                     /identifier="TIGR00763"
                     /label="SCO5285"
                     /locus_tag="SCO5285"
                     /protein_end="792"
                     /protein_start="13"
                     /score="785.5"
                     /tool="antismash"
                     /translation="PVLPLDDEVVLPGMVVPLDLSDAEVRAAVEAAQAAARSEPGKPRV
                     LLVPRIDGTHAATGVLGTVEQVGRLADGDPGALIRGRGRVRIGAGTTGPGAALWVEGTR
                     VDETVPDPLPGQVAELVKEYKALATAWLRKRGAWQVVDRVQAIDDVSALADNSGYSPFL
                     TTEQKVELLETTDPVARLKIATQQLRDHLAEQDVAETIAKDVQEGVDKQQREFLLRRQL
                     EAVRKELREINGEQEGEESDDYRARVEAADLPEKVREAALKEVDKLERSSDQSPEGSWI
                     RTWLDTVLEMPWSERTEDAYDIQGAQAVLDAEHAGLEDVKERITEYLAVRKRRGDRGLG
                     VVGGRRGGAVLALVGPPGVGKTSLGESVAHAMGRKFVRVALGGVRDEAEIRGHRRTYVG
                     ALPGRIVRAIKEAGSMNPVVLLDEIDKVGSDFRGDPAAALLEVLDPAQNHTFRDHYLEV
                     ELDLSDVVFLATANVLEAIPEALLDRMELVRLDGYTEDEKVVIARDHLLPRQLERAGLD
                     DDEVTVDEGALRKLAGEYTREAGVRTLERSIARLLRKVAAQHELGERELPFTVTEGDLR
                     SLIGRPHHVPESAQDPAERRTAVPGVATGLAVTGAGGDVLYVEASLADPETGAAGLTLT
                     GQLGDVMKESAQIALSFLRSHGAELELPVGDLKDRGAHIHFPAGAVPKDGPSAGVTMTT
                     ALASLLSGRLVRTDVAMTGEVSLTGRVLPIGGVKQKLLAAHRAGITTVIIPKRNEPDLD
                     DVPAQVLDKLDVHAVTDVRQVLELAL"
     misc_feature    5949..6536
                     /gene_synonym="lon; SCCB12.09"
                     /locus_tag="SCO5285"
                     /note="Pfam match to entry PF00004 AAA, ATPases associated
                     with various cellular activities (AAA), score 103.40,
                     E-value 4.6e-27"
     PFAM_domain     5955..6362
                     /aSDomain="AAA"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00004.32"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0016887"
                     /description="ATPase family associated with various
                     cellular activities (AAA)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5285_0485"
                     /evalue="2.20E-20"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0016887: ATP hydrolysis activity"
                     /label="SCO5285"
                     /locus_tag="SCO5285"
                     /protein_end="500"
                     /protein_start="364"
                     /score="73.6"
                     /tool="antismash"
                     /translation="ALVGPPGVGKTSLGESVAHAMGRKFVRVALGGVRDEAEIRGHRRT
                     YVGALPGRIVRAIKEAGSMNPVVLLDEIDKVGSDFRGDPAAALLEVLDPAQNHTFRDHY
                     LEVELDLSDVVFLATANVLEAIPEALLDRMEL"
     misc_feature    5964..5987
                     /gene_synonym="lon; SCCB12.09"
                     /locus_tag="SCO5285"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     PFAM_domain     6609..7241
                     /aSDomain="Lon_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05362.16"
                     /db_xref="GO:0004176"
                     /db_xref="GO:0004252"
                     /db_xref="GO:0006508"
                     /description="Lon protease (S16) C-terminal proteolytic
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5285_0486"
                     /evalue="4.70E-75"
                     /gene_ontologies="GO:0004176: ATP-dependent peptidase
                     activity"
                     /gene_ontologies="GO:0004252: serine-type endopeptidase
                     activity"
                     /gene_ontologies="GO:0006508: proteolysis"
                     /label="SCO5285"
                     /locus_tag="SCO5285"
                     /protein_end="793"
                     /protein_start="582"
                     /score="251.8"
                     /tool="antismash"
                     /translation="VTEGDLRSLIGRPHHVPESAQDPAERRTAVPGVATGLAVTGAGGD
                     VLYVEASLADPETGAAGLTLTGQLGDVMKESAQIALSFLRSHGAELELPVGDLKDRGAH
                     IHFPAGAVPKDGPSAGVTMTTALASLLSGRLVRTDVAMTGEVSLTGRVLPIGGVKQKLL
                     AAHRAGITTVIIPKRNEPDLDDVPAQVLDKLDVHAVTDVRQVLELALA"
     misc_feature    6951..6977
                     /gene_synonym="lon; SCCB12.09"
                     /locus_tag="SCO5285"
                     /note="PS01046 ATP-dependent serine proteases, lon family,
                     serine active site"
     gene            complement(7363..8190)
                     /db_xref="GeneID:1100727"
                     /gene_synonym="SCCB12.10c"
                     /locus_tag="SCO5286"
     CDS             complement(7363..8190)
                     /codon_start=1
                     /db_xref="GeneID:1100727"
                     /gene_synonym="SCCB12.10c"
                     /locus_tag="SCO5286"
                     /note="SCCB12.10c, probable hydrolase, len: 275 aa; similar
                     to SW:LYCM_STRGL (EMBL:M30645) Streptomyces globisporus
                     lysozyme M1 precursor (EC 3.2.1.17) Acm, 294 aa; fasta
                     scores: opt: 828 z-score: 944.2 E(): 0; 45.7% identity in
                     291 aa overlap and to TR:Q9RJP9 (EMBL:AL132991)
                     Streptomyces coelicolor lysozyme precursor SCF55.15, 279
                     aa; fasta scores: opt: 1425 z-score: 1618.9 E(): 0; 75.2%
                     identity in 270 aa overlap. Contains Pfam match to entry
                     PF01183 Glyco_hydro_25, Glycosyl hydrolases family 25 and
                     2x matches to Prosite entry PS00017 ATP/GTP-binding site
                     motif A (P-loop). Also contains possible N-terminal region
                     signal peptide sequence (possibly cleavable)"
                     /product="hydrolase"
                     /protein_id="NP_629431.1"
                     /transl_table=11
                     /translation="MLVHRSGSARGRRFAVTGILLAAFSLVFTLPADAASAADVPARGS
                     AHMGMGVAAHDGEHGTPVPGRAAQTEGVDVSSHQGNVAWSTLWNSGVKWAYAKATEGTY
                     YTNPYFAQQYNGSYNVGMIRGAYHFATPDTTSGATQANYFVDHGGGWSRDGKTLPGALD
                     IEWNPYGATCYGKSQSGMVSWIRDFLNTYKARTGRDAVIYTATSWWTQCTGNYGGFAAS
                     NPLWIARYASTVGTLPAGWGYYTMWQYTSSGPTVGDHNKFNGALDRVVALANG"
     PFAM_domain     complement(7420..7974)
                     /aSDomain="Glyco_hydro_25"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01183.23"
                     /db_xref="GO:0003796"
                     /db_xref="GO:0009253"
                     /db_xref="GO:0016998"
                     /description="Glycosyl hydrolases family 25"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5286_0487"
                     /evalue="3.60E-57"
                     /gene_ontologies="GO:0003796: lysozyme activity"
                     /gene_ontologies="GO:0009253: peptidoglycan catabolic
                     process"
                     /gene_ontologies="GO:0016998: cell wall macromolecule
                     catabolic process"
                     /label="SCO5286"
                     /locus_tag="SCO5286"
                     /protein_end="257"
                     /protein_start="72"
                     /score="193.7"
                     /tool="antismash"
                     /translation="VDVSSHQGNVAWSTLWNSGVKWAYAKATEGTYYTNPYFAQQYNGS
                     YNVGMIRGAYHFATPDTTSGATQANYFVDHGGGWSRDGKTLPGALDIEWNPYGATCYGK
                     SQSGMVSWIRDFLNTYKARTGRDAVIYTATSWWTQCTGNYGGFAASNPLWIARYASTVG
                     TLPAGWGYYTMWQYTSSGPTVG"
     misc_feature    complement(7651..7986)
                     /gene_synonym="SCCB12.10c"
                     /locus_tag="SCO5286"
                     /note="Pfam match to entry PF01183 Glyco_hydro_25, Glycosyl
                     hydrolases family 25, score 104.90, E-value 1.5e-27"
     misc_feature    complement(7660..7683)
                     /gene_synonym="SCCB12.10c"
                     /locus_tag="SCO5286"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     misc_feature    complement(7720..7743)
                     /gene_synonym="SCCB12.10c"
                     /locus_tag="SCO5286"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     regulatory      complement(8197..8201)
                     /regulatory_class="ribosome_binding_site"
     gene            8439..8933
                     /db_xref="GeneID:1100728"
                     /gene_synonym="SCCB12.11"
                     /locus_tag="SCO5287"
     CDS             8439..8933
                     /codon_start=1
                     /db_xref="GeneID:1100728"
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 97; E-value: 1.1e-29)"
                     /gene_kind="regulatory"
                     /gene_synonym="SCCB12.11"
                     /locus_tag="SCO5287"
                     /note="SCCB12.11, possible MarR-family transcriptional
                     regulator, len: 164 aa; similar to TR:Q9RL39 (EMBL:
                     AL121596) Streptomyces coelicolor MarR-family protein
                     SCF51.25, 148 aa; fasta scores: opt: 237 z-score: 290.2
                     E(): 1.1e-08; 37.6% identity in 141 aa overlap and to
                     SW:YXAD_BACSU (EMBL:AB005554) Bacillus subtilis
                     hypothetical transcriptional regulator on AsnH-GntR
                     intergenic region YxaD, 143 aa; fasta scores: opt: 234
                     z-score: 286.9 E(): 1.6e-08; 35.7% identity in 140 aa
                     overlap. Contains Pfam match to entry PF01047 MarR, MarR
                     family and possible helix-turn-helix motif at residues
                     72..93 (+3.73 SD)"
                     /product="MarR family transcriptional regulator"
                     /protein_id="NP_629432.1"
                     /transl_table=11
                     /translation="MHEDGNGGGRGGESHLSGSGVNQPEFLALERELTVLLRRARANQG
                     EMAREVHPDLESSAYGLLVRLGECGGQRATDLAAFIGVGKATMSRQLRALEELGLVARE
                     PDPADGRAWLVTLTPEGQERVGRVREARRARYARRLAGWDPREVTELARLLHELNRGME
                     K"
     misc_feature    8601..8912
                     /gene_synonym="SCCB12.11"
                     /locus_tag="SCO5287"
                     /note="Pfam match to entry PF01047 MarR, MarR family, score
                     99.30, E-value 7.3e-26"
     PFAM_domain     8610..8774
                     /aSDomain="MarR"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01047.25"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /description="MarR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5287_0488"
                     /evalue="2.10E-12"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO5287"
                     /locus_tag="SCO5287"
                     /protein_end="112"
                     /protein_start="57"
                     /score="46.9"
                     /tool="antismash"
                     /translation="SAYGLLVRLGECGGQRATDLAAFIGVGKATMSRQLRALEELGLVA
                     REPDPADGRA"
     gene            complement(8955..9746)
                     /db_xref="GeneID:1100729"
                     /gene_synonym="SCCB12.12c"
                     /locus_tag="SCO5288"
     CDS             complement(8955..9746)
                     /codon_start=1
                     /db_xref="GeneID:1100729"
                     /gene_synonym="SCCB12.12c"
                     /locus_tag="SCO5288"
                     /note="SCCB12.12c, unknown, len: 263 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_629433.1"
                     /transl_table=11
                     /translation="MRTELVSEPGLADQPNEDFASVGLPASGQGGSLVVLDGVTPPRTA
                     TGCLHSVPWFTARLGGALTELTVSLPDLPLAEALSRGIARTAAAHAETCDLSHPRTPQA
                     TVVLARWSAAAFEYLVLSDSALLLEAPDGTLTPVLDDRLARLPRSALVSDAVIDAGLRN
                     KEGGFFTAAADPAVAARAVTGVLPRGAVRTLAALTDGAARWVEKFGEGDWADCLALVRK
                     QGAQALVDRVRELERADAADGRAFLGRSKTHDDATVVYAEL"
     PFAM_domain     complement(9072..9710)
                     /aSDomain="PP2C_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13672.9"
                     /description="Protein phosphatase 2C"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5288_0489"
                     /evalue="5.60E-06"
                     /label="SCO5288"
                     /locus_tag="SCO5288"
                     /protein_end="225"
                     /protein_start="12"
                     /score="26.3"
                     /tool="antismash"
                     /translation="DQPNEDFASVGLPASGQGGSLVVLDGVTPPRTATGCLHSVPWFTA
                     RLGGALTELTVSLPDLPLAEALSRGIARTAAAHAETCDLSHPRTPQATVVLARWSAAAF
                     EYLVLSDSALLLEAPDGTLTPVLDDRLARLPRSALVSDAVIDAGLRNKEGGFFTAAADP
                     AVAARAVTGVLPRGAVRTLAALTDGAARWVEKFGEGDWADCLALVRKQGA"
     gene            10256..13195
                     /db_xref="GeneID:1100730"
                     /gene_synonym="cvnA5; SC6G9.44c; SCCB12.13"
                     /locus_tag="SCO5289"
     CDS             10256..13195
                     /codon_start=1
                     /db_xref="GeneID:1100730"
                     /gene_synonym="cvnA5; SC6G9.44c; SCCB12.13"
                     /locus_tag="SCO5289"
                     /note="SCCB12.13, cvnA5, hypothetical protein (fragment),
                     len: >191 aa; similar to C-terminal region of TR:O86525
                     (EMBL:AL031124) Streptomyces coelicolor hypothetical 139.7
                     kDa protein SC1C2.25c, 1329 aa; fasta scores: opt: 146
                     z-score: 152.5 E(): 0.5; 25.3% identity in 186 aa overlap.
                     Contains possible hydrophobic membrane spanning region;
                     SC6G9.44c, possible sensor kinase, len: 806 aa; weak
                     similarity to part of TR:O33492 (EMBL:AJ000330), StyS,
                     Pseudomonas sp. strain Y2 styrene sensor kinase (982 aa),
                     fasta scores; opt: 256 z-score: 230.5 E(): 1.6e-05, 24.7%
                     identity in 543 aa overlap. Similar to parts of other
                     S.coelicolor hypothetical proteins e.g. TR:O86525
                     (EMBL:AL031124) S.coelicolor hypothetical protein (1329 aa)
                     (31.5% identity in 821 aa overlap). Contains 11x degenerate
                     E(K/T)A repeats between codons 555 and 587. Contains
                     probable coiled-coil from 251 to 295 (45 residues) (Max
                     score: 1.500, probability 0.95). Contains Pfam match to
                     entry PF00672 DUF5, Domain found in bacterial signal
                     proteins and to entry PF00512 signal, Signal
                     carboxyl-terminal domain"
                     /product="two component sensor kinase"
                     /protein_id="NP_733660.1"
                     /transl_table=11
                     /translation="MGSAERTPGTSTPPQPPEAPVGKGRATHVRNRLIVAVAVVAAAVA
                     GAGAPSVVAASGQLHDSQELVTLAEQTQGALTLAHSLADERDEVTPYIAAGRPKSKAPS
                     EQRSARVDRQVEELRADTDTPASLREDLDAVAALRRAALTGKSTALEAHQAYSEAITEL
                     HALAEKLGEEMPPRAGSGAYALAELDTAVQQAAATRGLLLAALNVPSTTETVIDPVTGL
                     PTETTTSSDADAEQRDALAAAAQQARVRSDAALADFREGAPKEARGSFDATVAGPEVNS
                     AEKYLAGLTDEPTLSDRDLGTSTKRLDAALSARVDAMRGAESALYEKRVAALEQLRDDD
                     VTALEIRIAVLGALILLAVGIATALARTLTRPLSVLRRGSARLAGAADPTTEEPVAFTG
                     RNDEFAQVVRSVNALHTHAATLAGRVATLESDRKHLVGQRQKMADAREELRTELAESAA
                     QLEVVRKSIGSTFVSLALRTLGLVERQLAVIESLEEREQDPDRLATLFKLDHFATVMRR
                     HSENLLVLAGTEHVQHSASPVPLVDVVRAAVSEIERYERVRIAALPPHAHVAGFAADDL
                     SHLLAELMENATSFSPPDLPVEVSGWLLENGEVMLSVQDEGIGMATERLQRLNARLTDF
                     DPDAPYDQEGEDGLGLGLYVVARLAHRHGARVRLREQKQGGVAAVVVLPSPLLAAAPPA
                     ALAPTVPVSDGTGTFSLPGADAEANSNVLHGRTEKSEAAEKSETAERAGTAEKAEKAGT
                     AGKSETAEQGAGEDAGPGAEPVIDPLVASAEEAVRRAEADASHADAPQTPEPDEREDPA
                     GPVPPEPARETVSAQDGPAPGSDLPDDATMALFLPALAEPETRPETDPGPYAIGPDAHD
                     RVPDTAEETGGQQEPAPSTRAEPVTDKGLPKRTPKLTTPAAVPRPRTSGSVDADALRRR
                     LGGFRRGAEAGRRDVEAEIADRPGQDQAPDTGAGTTEEATGGTVEEASS"
     PFAM_domain     10484..11236
                     /aSDomain="NIT"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08376.13"
                     /description="Nitrate and nitrite sensing"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5289_0490"
                     /evalue="2.20E-34"
                     /label="SCO5289"
                     /locus_tag="SCO5289"
                     /protein_end="327"
                     /protein_start="76"
                     /score="120.0"
                     /tool="antismash"
                     /translation="TLAHSLADERDEVTPYIAAGRPKSKAPSEQRSARVDRQVEELRAD
                     TDTPASLREDLDAVAALRRAALTGKSTALEAHQAYSEAITELHALAEKLGEEMPPRAGS
                     GAYALAELDTAVQQAAATRGLLLAALNVPSTTETVIDPVTGLPTETTTSSDADAEQRDA
                     LAAAAQQARVRSDAALADFREGAPKEARGSFDATVAGPEVNSAEKYLAGLTDEPTLSDR
                     DLGTSTKRLDAALSARVDAMRGAESALYE"
     misc_feature    11294..11515
                     /gene_synonym="cvnA5; SC6G9.44c; SCCB12.13"
                     /locus_tag="SCO5289"
                     /note="Pfam match to entry PF00672 DUF5, Domain found in
                     bacterial signal proteins, score 31.30, E-value 2.2e-05"
     misc_feature    11711..12307
                     /gene_synonym="cvnA5; SC6G9.44c; SCCB12.13"
                     /locus_tag="SCO5289"
                     /note="Pfam match to entry PF00512 signal, Signal
                     carboxyl-terminal domain, score 3.30, E-value 1.6e-05"
     PFAM_domain     11975..12307
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02518.29"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5289_0491"
                     /evalue="2.00E-12"
                     /label="SCO5289"
                     /locus_tag="SCO5289"
                     /protein_end="684"
                     /protein_start="573"
                     /score="47.7"
                     /tool="antismash"
                     /translation="DDLSHLLAELMENATSFSPPDLPVEVSGWLLENGEVMLSVQDEGI
                     GMATERLQRLNARLTDFDPDAPYDQEGEDGLGLGLYVVARLAHRHGARVRLREQKQGGV
                     AAVVVLP"
     repeat_region   12437..12534
                     /gene_synonym="cvnA5; SC6G9.44c; SCCB12.13"
                     /locus_tag="SCO5289"
                     /note="repeat 3; 11x degenerate 9 bp repeats"
     gene            13270..13722
                     /db_xref="GeneID:1100731"
                     /gene_synonym="cvnB5; SC6G9.43c"
                     /locus_tag="SCO5290"
     CDS             13270..13722
                     /codon_start=1
                     /db_xref="GeneID:1100731"
                     /gene_synonym="cvnB5; SC6G9.43c"
                     /locus_tag="SCO5290"
                     /note="SC6G9.43c, cvnB5, conserved hypothetical protein,
                     len: 150 aa; similar to hypothetical proteins from S.
                     coelicolor and Mycobacterium tuberculosis e.g. TR:O86524
                     (EMBL:AL031124) S.coelicolor hypothetical protein (173 aa),
                     fasta scores; opt: 316 z-score: 394.7 E(): 1.2e-14, 48.1%
                     identity in 131 aa overlap and TR:O50393 (EMBL:AL009198)
                     Mycobacterium tuberculosis hypothetical protein (130 aa)
                     (36.7% identity in 120 aa overlap)"
                     /product="hypothetical protein"
                     /protein_id="NP_629434.1"
                     /transl_table=11
                     /translation="MPGIRSVAVVSSDGLLLLSSDPGRNEEARQARETPRAGPRGSAAD
                     LATVVSGVGSLTVGAARLMDFGPVKHTMVAMDEGSLFVMSISDGSLLGVHGSAECDMSV
                     VAYHMALFVGRAGHVLTPELRTELRKSLESESSESSVSSEPTGSAR"
     PFAM_domain     13393..13551
                     /aSDomain="Robl_LC7"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03259.20"
                     /description="Roadblock/LC7 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5290_0492"
                     /evalue="3.90E-05"
                     /label="SCO5290"
                     /locus_tag="SCO5290"
                     /protein_end="94"
                     /protein_start="41"
                     /score="23.4"
                     /tool="antismash"
                     /translation="SAADLATVVSGVGSLTVGAARLMDFGPVKHTMVAMDEGSLFVMSI
                     SDGSLLGV"
     gene            13719..14171
                     /db_xref="GeneID:1100732"
                     /gene_synonym="cvnC5; SC6G9.42c"
                     /locus_tag="SCO5291"
     CDS             13719..14171
                     /codon_start=1
                     /db_xref="GeneID:1100732"
                     /gene_synonym="cvnC5; SC6G9.42c"
                     /locus_tag="SCO5291"
                     /note="SC6G9.42c, cvnC5, conserved hypothetical protein,
                     len: 150 aa; similar to hypothetical proteins of varying
                     length (divergent at the N-terminus) from S. coelicolor and
                     Mycobacterium tuberculosis e.g. TR:O86523 (EMBL:AL031124)
                     S.coelicolor hypothetical protein (132 aa), fasta scores;
                     opt: 250 z-score: 312.1 E(): 4.7e-10, 43.7% identity in 135
                     aa overlap and TR:O50392 (EMBL:AL009198) Mycobacterium
                     tuberculosis hypothetical protein (122 aa) (37.4% identity
                     in 131 aa overlap)"
                     /product="hypothetical protein"
                     /protein_id="NP_629435.1"
                     /transl_table=11
                     /translation="MSSSPGKPGTNGRGNLPVRGADRKPARVRPYSLTGGRTRFGHVLL
                     VETFVGATAGTAALEAAEERRELTNGGLTSRVMPEMRAIVELCRRMRTVAEIAALLKMP
                     LGVVRVLLSDLADQGKIRVYGTGTGHGTGRPDRALLERVLSGLRRL"
     PFAM_domain     13782..14168
                     /aSDomain="DUF742"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05331.14"
                     /description="Protein of unknown function (DUF742)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5291_0493"
                     /evalue="3.70E-43"
                     /label="SCO5291"
                     /locus_tag="SCO5291"
                     /protein_end="150"
                     /protein_start="21"
                     /score="146.1"
                     /tool="antismash"
                     /translation="DRKPARVRPYSLTGGRTRFGHVLLVETFVGATAGTAALEAAEERR
                     ELTNGGLTSRVMPEMRAIVELCRRMRTVAEIAALLKMPLGVVRVLLSDLADQGKIRVYG
                     TGTGHGTGRPDRALLERVLSGLRRL"
     gene            14218..14793
                     /db_xref="GeneID:1100733"
                     /gene_synonym="cvnD5; SC6G9.41c"
                     /locus_tag="SCO5292"
     CDS             14218..14793
                     /codon_start=1
                     /db_xref="GeneID:1100733"
                     /gene_synonym="cvnD5; SC6G9.41c"
                     /locus_tag="SCO5292"
                     /note="SC6G9.41c, cvnD5, possible ATP/GTP-binding protein,
                     len: 191 aa; highly similar to others from S.coelicolor
                     e.g. TR:O86519 (EMBL:AL031124) S.coelicolor possible
                     ATP/GTP-binding protein (174 aa), fasta scores; opt: 766
                     z-score: 918.0 E(): 0, 68.0% identity in 169 aa overlap.
                     Although many of the presumed homologues start at the
                     equivalent of codon 18 in this CDS, there is no possible
                     initiation codon in this case. Also similar to hypothetical
                     proteins from other organisms e.g. TR:O5039 (EMBL:AL009198)
                     Mycobacterium tuberculosis hypothetical protein (193 aa)
                     (63.6% identity in 173 aa overlap). Similar to the
                     C-terminal half of TR:O26694 (EMBL:AE00084)
                     Methanobacterium thermoautotrophicum conserved protein (393
                     aa) (29.5% identity in 173 aa overlap). Contains PS00017
                     ATP/GTP-binding site motif A (P-loop)"
                     /product="ATP/GTP-binding protein"
                     /protein_id="NP_629436.1"
                     /transl_table=11
                     /translation="MQPWQTDPTRAPVATKIVVAGGFGVGKTTLVTAVSEITPLQTEAL
                     MTEASEETDDLTATPGKLTTTVAMDFGRITLDDDLVLYLFGTPGQQRFWFMWDDLVRGA
                     IGAVVLADTRRLKDCWPALDYFESCGLPYVVAVNHFDGSELFEAEDVREALTIPAHIPV
                     MIMDARRRISAIETLLSLVGHALDETPE"
     PFAM_domain     14272..14778
                     /aSDomain="ATP_bind_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03029.20"
                     /description="Conserved hypothetical ATP binding protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5292_0494"
                     /evalue="2.40E-29"
                     /label="SCO5292"
                     /locus_tag="SCO5292"
                     /protein_end="187"
                     /protein_start="18"
                     /score="103.0"
                     /tool="antismash"
                     /translation="VAGGFGVGKTTLVTAVSEITPLQTEALMTEASEETDDLTATPGKL
                     TTTVAMDFGRITLDDDLVLYLFGTPGQQRFWFMWDDLVRGAIGAVVLADTRRLKDCWPA
                     LDYFESCGLPYVVAVNHFDGSELFEAEDVREALTIPAHIPVMIMDARRRISAIETLLSL
                     VGHALD"
     misc_feature    14278..14301
                     /gene_synonym="cvnD5; SC6G9.41c"
                     /locus_tag="SCO5292"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     gene            14852..16114
                     /db_xref="GeneID:1100734"
                     /gene_synonym="SC6G9.40c"
                     /locus_tag="SCO5293"
     CDS             14852..16114
                     /codon_start=1
                     /db_xref="GeneID:1100734"
                     /gene_synonym="SC6G9.40c"
                     /locus_tag="SCO5293"
                     /note="SC6G9.40c, possible oxygenase subunit, len: 420 aa;
                     similar to Pseudomonas spp. styrene monoxygenase large
                     subunits e.g. TR:O06834 (EMBL:Z92524), styA, Pseudomonas
                     fluorescens main component of styrene monooxygenase (415
                     aa), fasta scores; opt: 481 z-score: 542.1 E(): 7.3e-23,
                     31.2% identity in 417 aa overlap. It has no neighbouring
                     CDS similar to the monoxygenase small subunit. The
                     C-terminus overlaps the C-terminus of the downstream ORF on
                     the opposite strand"
                     /product="oxygenase subunit"
                     /protein_id="NP_629437.1"
                     /transl_table=11
                     /translation="MRKILVVGAGQSGLQLALGLQSHGYEVTLMSNRTADEIRTGRVMS
                     TQCMFHTALQHERDLQLNFWESQAPKIEGLGVSVAAPGSFDPGPSQRAIDWLGHLDGFA
                     QSVDQRVKMAGWMETFAQRGGQLVIHGAAVGDLDYFSRAYDLVLVSAGKGELVQMFGRD
                     AERSPYSEPQRALAVAYVHGMGPRPEHPETEAVRCNLVPGVGEMFIMPTFTTSGRADIL
                     FWEGIPGGPLDAFKDVKDPAEHLSLTLELMEKFLPWEYARATKVELTDAGGTLAGRYAP
                     TVRNPVGRLPGGGAVLGVADVVVANDPITGQGSNSASKCAASYLASIIEHGDQEFDETW
                     MRQTFDRYWETAQHVTKWTNTMLAPPPEHILNLFGAATQLQPIADRFANGFNDPSDFEN
                     FFYDPAKTEGYLAEVSGAAGA"
     PFAM_domain     15305..15637
                     /aSDomain="Smoa_sbd"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF17885.4"
                     /description="Styrene monooxygenase A putative substrate
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5293_0495"
                     /evalue="2.00E-44"
                     /label="SCO5293"
                     /locus_tag="SCO5293"
                     /protein_end="262"
                     /protein_start="151"
                     /score="150.3"
                     /tool="antismash"
                     /translation="GKGELVQMFGRDAERSPYSEPQRALAVAYVHGMGPRPEHPETEAV
                     RCNLVPGVGEMFIMPTFTTSGRADILFWEGIPGGPLDAFKDVKDPAEHLSLTLELMEKF
                     LPWEYAR"
     gene            complement(16078..17253)
                     /db_xref="GeneID:1100735"
                     /gene_synonym="SC6G9.39"
                     /locus_tag="SCO5294"
     CDS             complement(16078..17253)
                     /codon_start=1
                     /db_xref="GeneID:1100735"
                     /gene_synonym="SC6G9.39"
                     /locus_tag="SCO5294"
                     /note="SC6G9.39, probable hypothetical protein, len: 391
                     aa; similar to mycobacterial hypothetical proteins e.g.
                     TR:O69580 (EMBL:AL022602) Mycobacterium leprae probable
                     hypothetical protein (374 aa), fasta scores; opt: 347
                     z-score: 354.0 E(): 2.2e-12, 29.1% identity in 337 aa
                     overlap. Similar to part of Listeria p60
                     attachment/invasion proteins e.g. SW:P60_LISWE
                     (EMBL:M80354) Listeria welshimeri protein p60 precursor
                     (524 aa) (37.8% identity in 98 aa overlap). Similar to
                     other hypothetical proteins from S.coelicolor e.g.
                     (EMBL:AL049497), SC6G10.08C, S.coelicolor hypothetical
                     protein (338 aa) (38.3% identity in 342 aa overlap).
                     Contains possible N-terminal signal sequence. The
                     C-terminus overlaps the C-terminus of the downstream ORF on
                     the opposite strand. Contains probable coiled-coils from 43
                     to 98 (56 residues) (Max score: 1.580, probability 0.99)
                     and from 164 to 201 (38 residues) (Max score: 1.531,
                     probability 0.97). Contains Pfam match to entry PF00877
                     NLPC_P60, NLP/P60 family (domain of unknown function)"
                     /product="hypothetical protein"
                     /protein_id="NP_629438.1"
                     /transl_table=11
                     /translation="MSGRLLRLVCTAALTAGIVLAPVPAAAGPGPGPGPAEGAAGDRTV
                     AGLLTDLQRLYREAERATETYNGTEERLKRQRARVLRLNAELTRTRLSLRDSRGAAGRL
                     ARQQYQNSSDFSPYLRLLLARDPQHALDQGHVIGRLSEERAETVGRLTGDTKKADELAG
                     RARAALARQAALAERQERERDGVRERLRAVEELLASLTPEQLAALAELEKSGIAEEQER
                     FLASGALGDDAKPSAGGESAVRFAVEQLGKPYQWGAEGPASYDCSGLTSVAWERAGTPI
                     PRTSQEQWARLDHVPLDELRPGDLVVYFPEATHVAMYLGDGMVVQAPRPGADVKVSPIA
                     ANPVLGAVRPDPGGEPVLRYTPPRLPAGATNGSDEGYAASYAPAAPETSAR"
     misc_feature    complement(16204..16518)
                     /gene_synonym="SC6G9.39"
                     /locus_tag="SCO5294"
                     /note="Pfam match to entry PF00877 NLPC_P60, NLP/P60
                     family, score 93.50, E-value 4.1e-24"
     PFAM_domain     complement(16234..16503)
                     /aSDomain="NLPC_P60"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00877.22"
                     /description="NlpC/P60 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5294_0496"
                     /evalue="2.70E-19"
                     /label="SCO5294"
                     /locus_tag="SCO5294"
                     /protein_end="340"
                     /protein_start="250"
                     /score="69.2"
                     /tool="antismash"
                     /translation="GKPYQWGAEGPASYDCSGLTSVAWERAGTPIPRTSQEQWARLDHV
                     PLDELRPGDLVVYFPEATHVAMYLGDGMVVQAPRPGADVKVSPIA"
     gene            complement(17357..17680)
                     /db_xref="GeneID:1100736"
                     /gene_synonym="SC6G9.38"
                     /locus_tag="SCO5295"
     CDS             complement(17357..17680)
                     /codon_start=1
                     /db_xref="GeneID:1100736"
                     /gene_synonym="SC6G9.38"
                     /locus_tag="SCO5295"
                     /note="SC6G9.38, hypothetical protein, len: 107 aa; unknown
                     function, probable CDS suggested by GC frameplot,
                     positional base preference and amino acid composition"
                     /product="hypothetical protein"
                     /protein_id="NP_629439.1"
                     /transl_table=11
                     /translation="MKSEDTPFEGGPMDGRVLPVLVGMTGHPPKTYRIPVPDPDGGPPT
                     VLVYRRVPRDSRGGLRFARWKYAYAPEGAKGSGRKWPWSKPERPSAAEPDATPGGKPDD
                     ADG"
     gene            complement(17751..18404)
                     /db_xref="GeneID:1100737"
                     /gene_synonym="SC6G9.37"
                     /locus_tag="SCO5296"
     CDS             complement(17751..18404)
                     /codon_start=1
                     /db_xref="GeneID:1100737"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 80.8; E-value: 2.8e-24)"
                     /gene_kind="regulatory"
                     /gene_synonym="SC6G9.37"
                     /locus_tag="SCO5296"
                     /note="SC6G9.37, possible tetR-family transcriptional
                     regulator, len: 217 aa; similar to many hypothetical
                     proteins, especially from mycobacteria e.g. TR:Q49662
                     (EMBL:U00012) Mycobacterium leprae hypothetical protein
                     (242 aa), fasta scores; opt: 216 z-score: 270.8 E():
                     9.4e-08, 28.8% identity in 222 aa overlap. Weak similarity
                     to some transcriptional regulators. Contains probable
                     helix-turn-helix motif at aa 39-60 (Score 1937, +5.78 SD).
                     Contains Pfam match to entry PF00440 tetR, Bacterial
                     regulatory proteins, tetR family"
                     /product="TetR family transcriptional regulator"
                     /protein_id="NP_629440.1"
                     /transl_table=11
                     /translation="MTPQAPTPAYRRLSVEERRVQLLDAALALFAHRPPEEVSLDDVAE
                     QAGVSRPLVYRYFPGGKQQLYEAALSSAADELRLCFDEPRKGPLLARLSRALDRYLTFV
                     DEHDTGFSALLRGGSVVETSQTSGIVDGVRRAAADHIMRHLDVAEPGPRLRMTVRMWIT
                     AVEAASLIWLDEDKQPPFDELRDWLVEQFLAVLTVTARRDPQSAALVETLAADL"
     misc_feature    complement(18198..18341)
                     /gene_synonym="SC6G9.37"
                     /locus_tag="SCO5296"
                     /note="Pfam match to entry PF00440 tetR, Bacterial
                     regulatory proteins, tetR family, score 27.50, E-value
                     7.2e-06"
     PFAM_domain     complement(18198..18341)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00440.26"
                     /db_xref="GO:0003677"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5296_0497"
                     /evalue="1.10E-15"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /label="SCO5296"
                     /locus_tag="SCO5296"
                     /protein_end="69"
                     /protein_start="21"
                     /score="57.3"
                     /tool="antismash"
                     /translation="LLDAALALFAHRPPEEVSLDDVAEQAGVSRPLVYRYFPGGKQQLY
                     EAA"
     repeat_region   18689..18709
                     /note="20 bp imperfect inverted repeat (1 mismatch)"
     repeat_region   complement(18689..19586)
                     /note="insertion element IS1650"
     gene            18713..19566
                     /db_xref="GeneID:1100738"
                     /gene_synonym="SC6G9.35c; SC6G9.36c"
                     /locus_tag="SCO5297"
                     /pseudo=""
     misc_feature    18713..19566
                     /gene_synonym="SC6G9.35c; SC6G9.36c"
                     /locus_tag="SCO5297"
                     /note="SC6G9.36c, probable transposase ORF1, len: 136 aa;
                     similar to parts of many transposases e.g. TR:Q44424
                     (EMBL:M55562) Agrobacterium tumefaciens IS427 ORF 4 (137
                     aa), fasta scores; opt: 334 z-score: 436.7 E(): 5.4e-17,
                     50.8% identity in 118 aa overlap. Similar to TR:O69927
                     (EMBL:AL02386) S.coelicolor IS1648 transposase (141 aa)
                     (60.5% identity in 119 aa overlap). May be translated by
                     frameshifting into the downstream ORF; SC6G9.35c, probable
                     transposase ORF2, len: 148 aa; similar to parts of many
                     transposases e.g. TR:Q46487 (EMBL:X75973) Clavibacter xyli
                     insertion sequence IS1237 transposase (308 aa), fasta
                     scores; 42.1% identity in 171 aa overlap. Similar to part
                     of TR:O69928 (EMBL:AL023861) S.coelicolor IS1648
                     transposase fragment (152 aa) (52.7% identity in 150 aa
                     overlap). May be translated as a result of frameshifting
                     from the upstream ORF;transposase"
                     /pseudo=""
     misc_feature    19069..19074
                     /gene_synonym="SC6G9.35c; SC6G9.36c"
                     /locus_tag="SCO5297"
                     /note="possible ribosomal frameshift site"
                     /pseudo=""
     repeat_region   complement(19566..19586)
                     /note="20 bp imperfect inverted repeat (1 mismatch)"
     gene            complement(19582..20520)
                     /db_xref="GeneID:1100739"
                     /gene_synonym="SC6G9.34"
                     /locus_tag="SCO5299"
     CDS             complement(19582..20520)
                     /codon_start=1
                     /db_xref="GeneID:1100739"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AurF"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC6G9.34"
                     /locus_tag="SCO5299"
                     /note="SC6G9.34, possible membrane protein, len: 312 aa;
                     unknown function, similar to proteins from Mycobacterium
                     leprae and Mycobacterium tuberculosis e.g. TR:O33063
                     (EMBL:Z99494) Mycobacterium leprae hypothetical protein
                     (341 aa), fasta scores; opt: 316 z-score: 387.1 E():
                     3.1e-14, 27.1% identity in 255 aa overlap (divergent at
                     C-terminus). Contains hydrophobic, possible
                     membrane-spanning region"
                     /product="hypothetical protein"
                     /protein_id="NP_629441.1"
                     /sec_met_domain="AurF (E-value: 6.5e-92, bitscore: 306.6,
                     seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLTEADALEGLRDALGLLKDREQVAERLLDSSAKHSFDPDKEL
                     DWDAPFEDGKWFWPPELVSLYDTPMWQRMSEEQRIALSQHEAAALASLGIWFELILMQL
                     LVRHIYDKAATSAHVRYALTEIEDECRHSKMFARLISRGETPWYPVSPVHQHLGRLFKT
                     ISTTPGSFTATLLGEEVLDWMQRLTFPDERVQPLIRGVTRIHVVEEARHVRYAREELRR
                     QMVTAPKWSQEFTRVTSGEFARVFSKAFINPEVYTNVGLDKREALAQVRASGHRKEIMQ
                     TGAKRLTDFLDDIGVLRGAGRKLWRSSGLLA"
     PFAM_domain     complement(19636..20460)
                     /aSDomain="AurF"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF11583.11"
                     /description="P-aminobenzoate N-oxygenase AurF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5299_0498"
                     /evalue="1.60E-91"
                     /label="SCO5299"
                     /locus_tag="SCO5299"
                     /protein_end="295"
                     /protein_start="20"
                     /score="306.6"
                     /tool="antismash"
                     /translation="KDREQVAERLLDSSAKHSFDPDKELDWDAPFEDGKWFWPPELVSL
                     YDTPMWQRMSEEQRIALSQHEAAALASLGIWFELILMQLLVRHIYDKAATSAHVRYALT
                     EIEDECRHSKMFARLISRGETPWYPVSPVHQHLGRLFKTISTTPGSFTATLLGEEVLDW
                     MQRLTFPDERVQPLIRGVTRIHVVEEARHVRYAREELRRQMVTAPKWSQEFTRVTSGEF
                     ARVFSKAFINPEVYTNVGLDKREALAQVRASGHRKEIMQTGAKRLTDFLDDIG"
     gene            complement(20668..21174)
                     /db_xref="GeneID:1100740"
                     /gene_synonym="SC6G9.33"
                     /locus_tag="SCO5300"
     CDS             complement(20668..21174)
                     /codon_start=1
                     /db_xref="GeneID:1100740"
                     /gene_synonym="SC6G9.33"
                     /locus_tag="SCO5300"
                     /note="SC6G9.33, hypothetical protein, len: 168 aa; unknown
                     function, probable CDS suggested by GC frameplot,
                     positional base preference and amino acid composition.
                     Alternative start codon present at codon 6. Similar to
                     TR:Q9A5F4 (EMBL:AE005918) Caulobacter crescentus
                     hypothetical protein CC2496, 185 aa; fasta scores: opt: 573
                     Z-score: 686.8 E(): 1.3e-30; 52.532% identity in 158 aa
                     overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_629442.1"
                     /transl_table=11
                     /translation="MTEDAVHELAQVNIARLKAPLDSPQLKDFVDALEPVNAAADAADG
                     FVWRLQSEGGDATDIPVFGDSWLIVNLTMWRDADALTAFMYQGRHREMLARRREWFERP
                     AEAVTALWWVPAGHRPTVAEAESRLRHLRTHGPTPYAFTLRTSYPAGASEPVPGEVPEG
                     LDCSV"
     PFAM_domain     complement(20737..21150)
                     /aSDomain="DUF3291"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF11695.11"
                     /description="Domain of unknown function (DUF3291)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5300_0499"
                     /evalue="2.80E-61"
                     /label="SCO5300"
                     /locus_tag="SCO5300"
                     /protein_end="146"
                     /protein_start="8"
                     /score="205.4"
                     /tool="antismash"
                     /translation="LAQVNIARLKAPLDSPQLKDFVDALEPVNAAADAADGFVWRLQSE
                     GGDATDIPVFGDSWLIVNLTMWRDADALTAFMYQGRHREMLARRREWFERPAEAVTALW
                     WVPAGHRPTVAEAESRLRHLRTHGPTPYAFTLRT"
     gene            complement(21220..22677)
                     /db_xref="GeneID:1100741"
                     /gene_synonym="SC6G9.32"
                     /locus_tag="SCO5301"
     CDS             complement(21220..22677)
                     /codon_start=1
                     /db_xref="GeneID:1100741"
                     /gene_synonym="SC6G9.32"
                     /locus_tag="SCO5301"
                     /note="SC6G9.32, possible penicillin-binding protein, len:
                     485 aa; similar to many e.g. to the C-terminal end of
                     SW:PBPC_BACSU (EMBL:D38161), PbpC, Bacillus subtilis
                     penicillin-binding protein 3 (668 aa), fasta scores; opt:
                     422 z-score: 451.6 E(): 8e-18, 27.6% identity in 384 aa
                     overlap. Similar to penicillin-binding proteins from
                     mycobacteria e.g. TR:P71586 (EMBL:Z80233) Mycobacterium
                     tuberculosis PpbA homologue (491 aa) (42.8% identity in 495
                     aa overlap). Contains a hydrophobic, possible membrane
                     anchor at the N-terminus. Contains Pfam match to entry
                     PF00905 Transpeptidase, Penicillin binding protein
                     transpeptidase domain and PS00017 ATP/GTP-binding site
                     motif A (P-loop)"
                     /product="penicillin-binding protein"
                     /protein_id="NP_629443.1"
                     /transl_table=11
                     /translation="MTRNIRHAAVFCALLLVALVVNAARVQIVQKPEYDDNPANRRPDI
                     ARYQQPRGDILVGGGAVTGSRDTGEHLRFERTYADGPMYAPITGFASQAYGTTLLEHAE
                     DGLLSGADPMLAPLPLWNDVTGAHNPGGDVVTTIHGAAQRAAFEGLGGRKGAVAAIEPA
                     TGRVLALVSTPSYDPQLLSGNSAAATRTWKRLNADPDKPMLNRAVSRTYPPGSTFKVVT
                     AAAALEAGVIRDLDAPTRSPDPYTLPGTRTKLTNEADGCRNASLREAFEWSCNTVFAKL
                     GVDVGVRGMTAMAEAFGFNDDGLRVPFPVARSTFDTSVDRAQLGLSSIGQYNTRATPLQ
                     MATVAAAVAGGGQVRSPYLVERTLRAGGSLVAAAGSRPSREVMRPSTAALLKELMTGVV
                     DKGTGAKAAIPGATVGGKTGTAQHGVGNSGTPYAWFISWARGAGDIEPKVAVAVVVEGT
                     ASDRQGVSGGGLAAPIARAVMEAVLGG"
     PFAM_domain     complement(21238..22215)
                     /aSDomain="Transpeptidase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00905.25"
                     /db_xref="GO:0008658"
                     /description="Penicillin binding protein transpeptidase
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5301_0500"
                     /evalue="2.90E-58"
                     /gene_ontologies="GO:0008658: penicillin binding"
                     /label="SCO5301"
                     /locus_tag="SCO5301"
                     /protein_end="480"
                     /protein_start="154"
                     /score="197.6"
                     /tool="antismash"
                     /translation="GAVAAIEPATGRVLALVSTPSYDPQLLSGNSAAATRTWKRLNADP
                     DKPMLNRAVSRTYPPGSTFKVVTAAAALEAGVIRDLDAPTRSPDPYTLPGTRTKLTNEA
                     DGCRNASLREAFEWSCNTVFAKLGVDVGVRGMTAMAEAFGFNDDGLRVPFPVARSTFDT
                     SVDRAQLGLSSIGQYNTRATPLQMATVAAAVAGGGQVRSPYLVERTLRAGGSLVAAAGS
                     RPSREVMRPSTAALLKELMTGVVDKGTGAKAAIPGATVGGKTGTAQHGVGNSGTPYAWF
                     ISWARGAGDIEPKVAVAVVVEGTASDRQGVSGGGLAAPIARAVME"
     misc_feature    complement(21247..22260)
                     /gene_synonym="SC6G9.32"
                     /locus_tag="SCO5301"
                     /note="Pfam match to entry PF00905 Transpeptidase,
                     Penicillin binding protein transpeptidase domain, score
                     249.30, E-value 5.5e-71"
     misc_feature    complement(21424..21447)
                     /gene_synonym="SC6G9.32"
                     /locus_tag="SCO5301"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     gene            complement(22694..24034)
                     /db_xref="GeneID:1100742"
                     /gene_synonym="SC6G9.31"
                     /locus_tag="SCO5302"
     CDS             complement(22694..24034)
                     /codon_start=1
                     /db_xref="GeneID:1100742"
                     /gene_synonym="SC6G9.31"
                     /locus_tag="SCO5302"
                     /note="SC6G9.31, probable integral membrane cell-cycle
                     protein, len: 446 aa; similar to members of the ftsW
                     (Escherichia coli cell division)/rodA (Escherichia coli
                     cell shape)/spoVE (Bacillus subtilis spore formation)
                     family e.g. SW:SP5E_BACSU (EMBL:X51419), spoVE, Bacillus
                     subtilis stage V sporulation protein E (366 aa), fasta
                     scores; opt: 461 z-score: 525.9 E(): 5.8e-22, 33.4%
                     identity in 371 aa overlap. Highly similar to proteins from
                     mycobacteria e.g. TR:FTSW_MYCLE (EMBL:Z70722), ftsW,
                     Mycobacterium leprae probable cell division protein (465
                     aa) (46.5% identity in 430 aa overlap). Contains
                     hydrophobic, possible membrane-spanning regions. Contains
                     Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle
                     protein"
                     /product="integral membrane cell-cycle protein"
                     /protein_id="NP_629444.1"
                     /transl_table=11
                     /translation="MAQADTPAPVARLPRRRGIELALILMAVLLSVFGYCNVGLAQHDA
                     LPPGAAGYGAGLGVLALLAHLAVRLRAPYADPLLLPIGVLLNGLGLVLIYRLDLETPGD
                     RAAPTQLVWSTLGVALFIVVVLLLRDHRVLQRYAYVCVAAALALLTVPIFFPAVNGARI
                     WIRIEGFSIQPGEFAKVLLAVFFAAYLAANRSALAYAGRRVWRLQLPTGRVLGPILAVW
                     LVSVGVLVLERDLGTSLLFFGLFVVLLYVATGRTGWIAVGLLLASLGAVAVGWLEPHVH
                     SRVEDWLHPFASIEAGHGPNQLAQSLFAFAAGGVTGTGLGLGHSVLIGFAVKSDFILAT
                     AGEELGFLGLSAVFLLYGLLVERGYRAGLGARDPFGRLLAVGLSSIVALQVFVIAGGVT
                     GLIPLTGMAMPFLAQGGSSVVTNWAIVALLIRVSHAARSQAGGRAEP"
     misc_feature    complement(22721..23809)
                     /gene_synonym="SC6G9.31"
                     /locus_tag="SCO5302"
                     /note="Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell
                     cycle protein, score 266.90, E-value 2.6e-76"
     PFAM_domain     complement(22724..23797)
                     /aSDomain="FTSW_RODA_SPOVE"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01098.22"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0051301"
                     /description="Cell cycle protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5302_0501"
                     /evalue="2.20E-73"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0051301: cell division"
                     /label="SCO5302"
                     /locus_tag="SCO5302"
                     /protein_end="437"
                     /protein_start="79"
                     /score="247.4"
                     /tool="antismash"
                     /translation="LPIGVLLNGLGLVLIYRLDLETPGDRAAPTQLVWSTLGVALFIVV
                     VLLLRDHRVLQRYAYVCVAAALALLTVPIFFPAVNGARIWIRIEGFSIQPGEFAKVLLA
                     VFFAAYLAANRSALAYAGRRVWRLQLPTGRVLGPILAVWLVSVGVLVLERDLGTSLLFF
                     GLFVVLLYVATGRTGWIAVGLLLASLGAVAVGWLEPHVHSRVEDWLHPFASIEAGHGPN
                     QLAQSLFAFAAGGVTGTGLGLGHSVLIGFAVKSDFILATAGEELGFLGLSAVFLLYGLL
                     VERGYRAGLGARDPFGRLLAVGLSSIVALQVFVIAGGVTGLIPLTGMAMPFLAQGGSSV
                     VTNWAIVALLIRVSHAAR"
     gene            complement(24111..24578)
                     /db_xref="GeneID:1100743"
                     /gene_synonym="SC6G9.30"
                     /locus_tag="SCO5303"
     CDS             complement(24111..24578)
                     /codon_start=1
                     /db_xref="GeneID:1100743"
                     /gene_synonym="SC6G9.30"
                     /locus_tag="SCO5303"
                     /note="SC6G9.30, possible membrane protein, len: 155 aa;
                     unknown function, probable CDS suggested by GC frameplot,
                     positional base preference and amino acid composition.
                     Contains hydrophobic, possible membrane-spanning region
                     near the N-terminus"
                     /product="hypothetical protein"
                     /protein_id="NP_629445.1"
                     /transl_table=11
                     /translation="MSPLSAPASRSPLVRGLATALAAGALATAVAVTPAAANDEWGGDA
                     GSTSAVTGGGNRGGDGGGSGGGAWGGSDGRQEQGRYRGVVTADRLALRTSPSRGADVIR
                     YARRGEVVSIYCKTPGSRVQGNPLWYLLTDGTWAWGAARYIDNIGPAPRWC"
     PFAM_domain     complement(24144..24314)
                     /aSDomain="SH3_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08239.14"
                     /description="Bacterial SH3 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5303_0502"
                     /evalue="4.30E-08"
                     /label="SCO5303"
                     /locus_tag="SCO5303"
                     /protein_end="145"
                     /protein_start="88"
                     /score="33.6"
                     /tool="antismash"
                     /translation="RLALRTSPSRGADVIRYARRGEVVSIYCKTPGSRVQGNPLWYLLT
                     DGTWAWGAARYI"
     gene            complement(24686..25930)
                     /db_xref="GeneID:1100744"
                     /gene_synonym="SC6G9.29"
                     /locus_tag="SCO5304"
     CDS             complement(24686..25930)
                     /codon_start=1
                     /db_xref="GeneID:1100744"
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 137.9; E-value: 9.7e-42)"
                     /gene_kind="regulatory"
                     /gene_synonym="SC6G9.29"
                     /locus_tag="SCO5304"
                     /note="SC6G9.29, possible sensor-like histidine kinase,
                     len: 414 aa; similar to many sensor histidine kinases from
                     two-component systems e.g. (EMBL:AJ13121), CseC,
                     S.coelicolor sensory histidine kinase of two-component
                     system regulating sigE transcription (507 aa), fasta
                     scores; opt: 966 z-score: 1051.7 E(): 0, 44.3% identity in
                     429 aa overlap. This protein does not have an obvious
                     response regulator companion. Similar to part of another
                     lone sensor-like histidine kinase TR:O05890 (EMBL:Z95121),
                     Mycobacterium tuberculosis sensor-like histidine kinase
                     (567 aa) (33.8% identity in 397 aa overlap). Contains
                     hydrophobic, possible membrane-spanning regions. Contains
                     Pfam matches to entry PF00672 DUF5, Domain found in
                     bacterial signal proteins and to entry PF00512 signal,
                     Signal carboxyl-terminal domain. Contains possible
                     hydrophobic membrane spanning regions"
                     /product="sensor-like histidine kinase"
                     /protein_id="NP_629446.1"
                     /transl_table=11
                     /translation="MRLALPRWTGPLAVKAAVFITVMCCGLAALLGVLVHVSVTNRTVG
                     QARDAALSRLGEATESYEAGDPLRRGAGIDPAGLPRQLRELAASGRRGTMLAEYAGRPT
                     MWAAGPADGGRALAVRVDHSQGQATIDGLDGTLVWSSALAIGATLLVGAFAVTRVTRRL
                     HTTARVARRISAGDLDARVGDPRAQDPTRPQDEVASVAAALDSMASSLQGKLLAEQRFT
                     ADVAHELRTPLTGLHAAAELLPPGRPTELVRDRVAALRTLTEDLLEISRLESGRERPAT
                     EPEELGALVRRVLRGSGTDTRVDVVRDARVETDRRRLERVLGNLVANAHRHGRAPVVLT
                     VDGAVITVRDHGDGYPEYLLAHGPQRFRTEGGAKGHGLGLTIALGQAEVLGARLEFTNP
                     PDGGALARLTLPQQP"
     PFAM_domain     complement(24695..24994)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02518.29"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5304_0505"
                     /evalue="1.90E-09"
                     /label="SCO5304"
                     /locus_tag="SCO5304"
                     /protein_end="412"
                     /protein_start="312"
                     /score="38.2"
                     /tool="antismash"
                     /translation="TDRRRLERVLGNLVANAHRHGRAPVVLTVDGAVITVRDHGDGYPE
                     YLLAHGPQRFRTEGGAKGHGLGLTIALGQAEVLGARLEFTNPPDGGALARLTLPQ"
     misc_feature    complement(24698..25252)
                     /gene_synonym="SC6G9.29"
                     /locus_tag="SCO5304"
                     /note="Pfam match to entry PF00512 signal, Signal
                     carboxyl-terminal domain, score 90.80, E-value 2.8e-23"
     PFAM_domain     complement(25106..25279)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00512.28"
                     /db_xref="GO:0000155"
                     /db_xref="GO:0007165"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5304_0504"
                     /evalue="4.60E-11"
                     /gene_ontologies="GO:0000155: phosphorelay sensor kinase
                     activity"
                     /gene_ontologies="GO:0007165: signal transduction"
                     /label="SCO5304"
                     /locus_tag="SCO5304"
                     /protein_end="275"
                     /protein_start="217"
                     /score="42.7"
                     /tool="antismash"
                     /translation="EQRFTADVAHELRTPLTGLHAAAELLPPGRPTELVRDRVAALRTL
                     TEDLLEISRLESG"
     misc_feature    complement(25292..25522)
                     /gene_synonym="SC6G9.29"
                     /locus_tag="SCO5304"
                     /note="Pfam match to entry PF00672 DUF5, Domain found in
                     bacterial signal proteins, score 44.70, E-value 2.1e-09"
     PFAM_domain     complement(25295..25465)
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00672.28"
                     /db_xref="GO:0007165"
                     /db_xref="GO:0016020"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5304_0503"
                     /evalue="5.80E-10"
                     /gene_ontologies="GO:0007165: signal transduction"
                     /gene_ontologies="GO:0016020: membrane"
                     /label="SCO5304"
                     /locus_tag="SCO5304"
                     /protein_end="212"
                     /protein_start="155"
                     /score="39.5"
                     /tool="antismash"
                     /translation="VTRVTRRLHTTARVARRISAGDLDARVGDPRAQDPTRPQDEVASV
                     AAALDSMASSLQ"
     gene            complement(25927..26745)
                     /db_xref="GeneID:1100745"
                     /gene_synonym="SC6G9.28"
                     /locus_tag="SCO5305"
     CDS             complement(25927..26745)
                     /codon_start=1
                     /db_xref="GeneID:1100745"
                     /gene_synonym="SC6G9.28"
                     /locus_tag="SCO5305"
                     /note="SC6G9.28, possible lipoprotein, len: 272 aa; unknown
                     function, probable CDS suggested by GC frameplot,
                     positional base preference and amino acid composition.
                     Contains appropriately positioned PS00013 Prokaryotic
                     membrane lipoprotein lipid attachment site"
                     /product="lipoprotein"
                     /protein_id="NP_629447.1"
                     /transl_table=11
                     /translation="MLPSRRGRPARVPAALALLLATAATGVLAACGDTGGLESAGATPA
                     AHHPARLWPGLTPASSPAYDIGEVEHAPMKGVAVPGGDIRRADPVAAVRAEIAAHPDDY
                     AGAGARYHETSARMADCGADGAGDEPGGCPVLRPYYRDLTGDGRPEMTLGFRLLPDRLT
                     AVRVYTVEKDRLVRIMSYEDAVSAVELAGRTVIVRSPSEVAGYEYRLQWTWDADQRAML
                     LTSDEMLRTDDGGRHARRPSASPSPSVSRSAAPPSSPPAAPSASPSASAR"
     misc_feature    complement(26653..26685)
                     /gene_synonym="SC6G9.28"
                     /locus_tag="SCO5305"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site"
     gene            complement(26873..27352)
                     /db_xref="GeneID:1100746"
                     /gene_synonym="SC6G9.27"
                     /locus_tag="SCO5306"
     CDS             complement(26873..27352)
                     /codon_start=1
                     /db_xref="GeneID:1100746"
                     /gene_synonym="SC6G9.27"
                     /locus_tag="SCO5306"
                     /note="SC6G9.27, possible protein phosphatase, len: 159 aa;
                     very weak similarity to eukaryotic tyrosine and
                     dual-specificity protein phosphatases e.g. TR:O70275
                     (EMBL:AF035645) Mus musculus protein tyrosine phosphatase
                     4A3 (173 aa), fasta scores; opt: 130 z-score: 173.4 E():
                     0.025, 33.3% identity in 78 aa overlap. Alternative start
                     codons are present at codons 12 and 17. Contains Pfam match
                     to entry PF00782 DSPc, Dual specificity phosphatase,
                     catalytic domain"
                     /product="protein phosphatase"
                     /protein_id="NP_629448.1"
                     /transl_table=11
                     /translation="MPAPDRPWDEIVPGLWMGGHEFRPTPGRLEFAVVRDEFDLVQTLL
                     RLPGHGPDEGVEHHVWPIPDGPLDGTQLAGVIRLARAADEALDGGRKVLVRCYHGYNRS
                     GLVVAHTLMRRGSGAEEAIRLVRARRSPWALHNELFVAYLRTGLATVRLLEEPAE"
     misc_feature    complement(26918..27334)
                     /gene_synonym="SC6G9.27"
                     /locus_tag="SCO5306"
                     /note="Pfam match to entry PF00782 DSPc, Dual specificity
                     phosphatase, catalytic domain, score -10.00, E-value
                     0.0075"
     PFAM_domain     complement(26921..27103)
                     /aSDomain="DSPc"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00782.23"
                     /db_xref="GO:0008138"
                     /db_xref="GO:0016311"
                     /description="Dual specificity phosphatase, catalytic
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5306_0506"
                     /evalue="1.70E-09"
                     /gene_ontologies="GO:0008138: protein
                     tyrosine/serine/threonine phosphatase activity"
                     /gene_ontologies="GO:0016311: dephosphorylation"
                     /label="SCO5306"
                     /locus_tag="SCO5306"
                     /protein_end="144"
                     /protein_start="83"
                     /score="37.7"
                     /tool="antismash"
                     /translation="DEALDGGRKVLVRCYHGYNRSGLVVAHTLMRRGSGAEEAIRLVRA
                     RRSPWALHNELFVAYL"
     gene            27466..28290
                     /db_xref="GeneID:1100747"
                     /gene_synonym="SC6G9.26c"
                     /locus_tag="SCO5307"
     CDS             27466..28290
                     /codon_start=1
                     /db_xref="GeneID:1100747"
                     /gene_synonym="SC6G9.26c"
                     /locus_tag="SCO5307"
                     /note="SC6G9.26c, hypothetical protein, len: 274 aa;
                     unknown function, probable CDS suggested by GC frameplot,
                     positional base preference and amino acid composition.
                     Alternative start codons are present at codons 8 and 14"
                     /product="hypothetical protein"
                     /protein_id="NP_629449.1"
                     /transl_table=11
                     /translation="MDGGGDGMDGLRVVPTRRHGRERLYVCLPDGGNVAWYDREEARVS
                     LLSDDRRAEVLQALAPFVTGPVTVGPPPVPTPAELARLTLHPDDDLAPNRPGEALLVAL
                     ERAPGPAHRLRPDPRRRALAAEQATGTALDRLDGAGLHTLHSLPLPGGDRIHHLLIGPG
                     GLFALHVLPARGQRVRVADPLVALGRRTPRPLLDRVRADADRASYALTAEVHPVLVLAG
                     PAHVTVTAPPRSVRVLTDRELPDLARTGGVLKPADVEALHAMARDRATWQGV"
     gene            complement(28382..29263)
                     /db_xref="GeneID:1100748"
                     /gene_synonym="SC6G9.25"
                     /locus_tag="SCO5308"
     CDS             complement(28382..29263)
                     /codon_start=1
                     /db_xref="GeneID:1100748"
                     /gene_synonym="SC6G9.25"
                     /locus_tag="SCO5308"
                     /note="SC6G9.25, conserved hypothetical protein, len: 293
                     aa; unknown function, similar to the N-terminal ends of
                     hypothetical proteins from Mycobacterium tuberculosis e.g.
                     TR:P95226 (EMBL:Z86089) Mycobacterium tuberculosis
                     hypothetical protein (397 aa), fasta scores; opt: 534
                     z-score: 643.4 E(): 1.7e-28, 36.6% identity in 292 aa
                     overlap and to the C-terminal end of TR:O34398
                     (EMBL:Z99110) Bacillus subtilis hypothetical protein (611
                     aa) (29.8% identity in 282 aa overlap). Also similar to S.
                     coelicolor hypothetical protein SC4C6.19 (341 aa) (34.6%
                     identity in 295 aa overlap) and (EMBL:AL033505), SC1E6.07,
                     S.coelicolor hypothetical protein (319 aa) (32.8% identity
                     in 259 aa overlap). Alternative start codons are present at
                     codons 4, 7, 12 and 20"
                     /product="hypothetical protein"
                     /protein_id="NP_629450.1"
                     /transl_table=11
                     /translation="MAPMTEVEGRRVALSNLDKVLYPAAGLTKGELLHYYATTAEVLLP
                     HLRDRAVSFLRYPDGPDGQVFFTKNVPPGTPDWVTTAEVPRSEGPARMVLVQDLASLMW
                     AANLVTEFHTHQWTVDDPGEADRLVFDLDPGPPATVVQCCEVALWLRERLAADGIEAYA
                     KTSGAKGLHLLAGVRGASSERVSEYAKGLAVEAERALPELVVHRMTRSLRPGKVFVDWS
                     QNAARKTTAAPYTVRARGVPAVSTPVTWEEVAGCGRAERFVFLTPDVGRRVRDHGDLLA
                     PLFDRRRAAALP"
     aSDomain        complement(28502..29230)
                     /aSDomain="TIGR02778"
                     /aSTool="tigrfam"
                     /description="ligD_pol: DNA ligase D, polymerase domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5308_0063"
                     /evalue="5.60E-85"
                     /identifier="TIGR02778"
                     /label="SCO5308"
                     /locus_tag="SCO5308"
                     /protein_end="254"
                     /protein_start="11"
                     /score="282.9"
                     /tool="antismash"
                     /translation="VALSNLDKVLYPAAGLTKGELLHYYATTAEVLLPHLRDRAVSFLR
                     YPDGPDGQVFFTKNVPPGTPDWVTTAEVPRSEGPARMVLVQDLASLMWAANLVTEFHTH
                     QWTVDDPGEADRLVFDLDPGPPATVVQCCEVALWLRERLAADGIEAYAKTSGAKGLHLL
                     AGVRGASSERVSEYAKGLAVEAERALPELVVHRMTRSLRPGKVFVDWSQNAARKTTAAP
                     YTVRARGVPAVSTPVTWEEVA"
     gene            29310..30407
                     /db_xref="GeneID:1100749"
                     /gene_synonym="SC6G9.24c"
                     /locus_tag="SCO5309"
     CDS             29310..30407
                     /codon_start=1
                     /db_xref="GeneID:1100749"
                     /gene_synonym="SC6G9.24c"
                     /locus_tag="SCO5309"
                     /note="SC6G9.24c, conserved hypothetical protein, len: 365
                     aa; unknown function, similar to hypothetical proteins from
                     Mycobacterium tuberculosis, Bacillus subtilis and
                     Archaeoglobus fulgidus e.g. TR:O05866 (EMBL:Z95209)
                     Mycobacterium tuberculosis hypothetical protein (273 aa),
                     fasta scores; opt: 648 z-score: 651.9 E(): 5.6e-29, 36.5%
                     identity in 274 aa overlap. An alternative start codon is
                     present as codon 4"
                     /product="hypothetical protein"
                     /protein_id="NP_629451.1"
                     /transl_table=11
                     /translation="MLHVRSIWNGAISFGLVSIPIKLVNATESHSVSFRQIHTEDGGRI
                     RYRKVCELEDREVTQAEIGKAYEDADGSMIPITDEDLSQLPIPTARTIEIVAFVPEDRI
                     DPLQMGSAYYLAASGAPAAKPYTLLREALKRSNRVAIAKFALRGRERLGMLRVVGDAIA
                     MHGLLWPDEVRAPEGVAPEGGVTVRDQELDLADALMDTLGEIDLDDLHDEYREAVEEVV
                     AAKASGEKPPEAREEAAPGKVLDLMAALESSVRAARESRDGEGAGPAEEAEVRSLSRRK
                     TSSRAPKETGGKKSTSTAAKKTAAKRAEPKKSTAKAAGSAKKTAAGSPAKGTAKKATAR
                     STARSGDKGAAKSTAKKTASRRRSA"
     aSDomain        29319..30080
                     /aSDomain="TIGR02772"
                     /aSTool="tigrfam"
                     /description="Ku_bact: Ku protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5309_0064"
                     /evalue="1.20E-90"
                     /identifier="TIGR02772"
                     /label="SCO5309"
                     /locus_tag="SCO5309"
                     /protein_end="257"
                     /protein_start="3"
                     /score="301.5"
                     /tool="antismash"
                     /translation="VRSIWNGAISFGLVSIPIKLVNATESHSVSFRQIHTEDGGRIRYR
                     KVCELEDREVTQAEIGKAYEDADGSMIPITDEDLSQLPIPTARTIEIVAFVPEDRIDPL
                     QMGSAYYLAASGAPAAKPYTLLREALKRSNRVAIAKFALRGRERLGMLRVVGDAIAMHG
                     LLWPDEVRAPEGVAPEGGVTVRDQELDLADALMDTLGEIDLDDLHDEYREAVEEVVAAK
                     ASGEKPPEAREEAAPGKVLDLMAALESSVRAA"
     PFAM_domain     29349..29840
                     /aSDomain="Ku"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02735.19"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0006303"
                     /description="Ku70/Ku80 beta-barrel domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5309_0507"
                     /evalue="1.90E-29"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0006303: double-strand break repair
                     via nonhomologous end joining"
                     /label="SCO5309"
                     /locus_tag="SCO5309"
                     /protein_end="177"
                     /protein_start="13"
                     /score="102.9"
                     /tool="antismash"
                     /translation="FGLVSIPIKLVNATESHSVSFRQIHTEDGGRIRYRKVCELEDREV
                     TQAEIGKAYEDADGSMIPITDEDLSQLPIPTARTIEIVAFVPEDRIDPLQMGSAYYLAA
                     SGAPAAKPYTLLREALKRSNRVAIAKFALRGRERLGMLRVVGDAIAMHGLLWPDEVRAP
                     E"
     gene            complement(30430..30993)
                     /db_xref="GeneID:1100750"
                     /gene_synonym="SC6G9.23"
                     /locus_tag="SCO5310"
     CDS             complement(30430..30993)
                     /codon_start=1
                     /db_xref="GeneID:1100750"
                     /gene_synonym="SC6G9.23"
                     /locus_tag="SCO5310"
                     /note="SC6G9.23, hypothetical protein, len: 187 aa; unknown
                     function, probable CDS suggested by GC frameplot,
                     positional base preference, amino acid composition and the
                     presence of a possible RBS"
                     /product="hypothetical protein"
                     /protein_id="NP_629452.1"
                     /transl_table=11
                     /translation="MTASGPGGGDTPDGPDDAPVVPEYVWRLFLEDDERAIHASAPREP
                     AARDRIPGRTRPEPPADCSGHPGRAHDTVGEPWRREDAWAGPAWRELDGRARLRRTGRV
                     LGTAAAVALAVTAWSQLTTGPATPGGGPAETIGQRLEESPALPSPASVADTPASAESAG
                     ASPAAFEPAPSAIPRAPASTRTFG"
     regulatory      complement(31003..31008)
                     /note="possible RBS"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(31282..32028)
                     /db_xref="GeneID:1100751"
                     /gene_synonym="SC6G9.22"
                     /locus_tag="SCO5311"
     CDS             complement(31282..32028)
                     /codon_start=1
                     /db_xref="GeneID:1100751"
                     /gene_synonym="SC6G9.22"
                     /locus_tag="SCO5311"
                     /note="SC6G9.22, possible hypothetical protein, len: 248
                     aa; unknown function, probable CDS suggested by GC
                     frameplot, positional base preference and amino acid
                     composition. Contains possible N-terminal signal sequence"
                     /product="hypothetical protein"
                     /protein_id="NP_629453.1"
                     /transl_table=11
                     /translation="MRLSRSRIGVVVLFGAMTLTLTALAFPAVLGLDKADGNQNRVVAS
                     TKFGPLTEADRDFVVKVRAAGLWEYPLGEMVMERGTTKAMKTAGEHLVVGHAGLDAMCR
                     EISPELGITLPNRASPQQEGFVAAVDAESGREFDSSAVNIMRVTHGQIFPAIAKIRAST
                     KNTLVRQLADLANDTVLDHITVLEKTGLVEYDDVTFKQTGPAKLPREKVTPPPPQPGER
                     VLVLKPRPDLNVNTASPTPAPSPAAP"
     PFAM_domain     complement(31471..31869)
                     /aSDomain="DUF4142"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13628.9"
                     /description="Domain of unknown function (DUF4142)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5311_0508"
                     /evalue="2.90E-11"
                     /label="SCO5311"
                     /locus_tag="SCO5311"
                     /protein_end="186"
                     /protein_start="53"
                     /score="43.9"
                     /tool="antismash"
                     /translation="ADRDFVVKVRAAGLWEYPLGEMVMERGTTKAMKTAGEHLVVGHAG
                     LDAMCREISPELGITLPNRASPQQEGFVAAVDAESGREFDSSAVNIMRVTHGQIFPAIA
                     KIRASTKNTLVRQLADLANDTVLDHITVL"
     regulatory      complement(32033..32037)
                     /note="possible RBS"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(32192..32626)
                     /db_xref="GeneID:1100752"
                     /gene_synonym="SC6G9.21"
                     /locus_tag="SCO5312"
     CDS             complement(32192..32626)
                     /codon_start=1
                     /db_xref="GeneID:1100752"
                     /gene_synonym="SC6G9.21"
                     /locus_tag="SCO5312"
                     /note="SC6G9.21, conserved hypothetical protein, len: 144
                     aa; unknown function, similar to hypothetical proteins from
                     Mycobacterium tuberculosis e.g. TR:O06553 (EMBL:Z95584)
                     Mycobacterium tuberculosis hypothetical protein (147 aa),
                     fasta scores; opt: 478 z-score: 561.4 E(): 6.1e-24, 55.7%
                     identity in 140 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_629454.1"
                     /transl_table=11
                     /translation="MTTTPRFDPRVLLAESRLGVLATIKSDGRPQLSPVMPAYDPEAGV
                     IRVSTREGLAKTANLRRDPRAALEVTAPDGRSWATAEGVATLTGPGADPHGPEVEALVE
                     YYRAAAGEHPDWDEYRSTMVSDRRVLLTITVERVYGADIG"
     aSDomain        complement(32207..32599)
                     /aSDomain="TIGR03618"
                     /aSTool="tigrfam"
                     /description="Rv1155_F420: PPOX class probable
                     F420-dependent enzyme"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5312_0065"
                     /evalue="1.90E-43"
                     /identifier="TIGR03618"
                     /label="SCO5312"
                     /locus_tag="SCO5312"
                     /protein_end="140"
                     /protein_start="9"
                     /score="145.7"
                     /tool="antismash"
                     /translation="RVLLAESRLGVLATIKSDGRPQLSPVMPAYDPEAGVIRVSTREGL
                     AKTANLRRDPRAALEVTAPDGRSWATAEGVATLTGPGADPHGPEVEALVEYYRAAAGEH
                     PDWDEYRSTMVSDRRVLLTITVERVYG"
     PFAM_domain     complement(32363..32593)
                     /aSDomain="Putative_PNPOx"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01243.23"
                     /description="Pyridoxamine 5'-phosphate oxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5312_0509"
                     /evalue="9.10E-15"
                     /label="SCO5312"
                     /locus_tag="SCO5312"
                     /protein_end="88"
                     /protein_start="11"
                     /score="54.7"
                     /tool="antismash"
                     /translation="LLAESRLGVLATIKSDGRPQLSPVMPAYDPEAGVIRVSTREGLAK
                     TANLRRDPRAALEVTAPDGRSWATAEGVATLT"
     gene            complement(32653..33564)
                     /db_xref="GeneID:1100753"
                     /gene_synonym="SC6G9.20"
                     /locus_tag="SCO5313"
     CDS             complement(32653..33564)
                     /codon_start=1
                     /db_xref="GeneID:1100753"
                     /gene_synonym="SC6G9.20"
                     /locus_tag="SCO5313"
                     /note="SC6G9.20, possible membrane protein, len: 303 aa;
                     unknown function, C-terminal half shows weak similarity to
                     the corresponding region of TR:O05859 (EMBL:Z95120)
                     Mycobacterium tuberculosis hypothetical protein (285 aa),
                     fasta scores; opt: 285 z-score: 275.6 E(): 5e-08, 31.4%
                     identity in 277 aa overlap. Contains a hydrophobic,
                     possible membrane-spanning region near the N-terminus.
                     Contains PS00142 Neutral zinc metallopeptidases,
                     zinc-binding region signature"
                     /product="hypothetical protein"
                     /protein_id="NP_629455.1"
                     /transl_table=11
                     /translation="MGRSTARRADRRTGPDGSGHRSRARRRSRRGPARAVLACLALGAV
                     LLTAGAAVAYWRETRPPVTDDQVADVTDALDATTRTPSASPSPSASPSPKASASPSASP
                     SSSPSATTIAIPATGPGTFVTARADGTTVGTGSRVRRYKVLVEKGIDVRPSAAAAEISE
                     VLADRRGWTQDGTNSFRLVSSGSYDFVVKIATPGTVDRICGAAGLLTRGEVNCSVGTDV
                     VVNLKRWVLGSPEFDGPIHEYRALIVNHEVGHRIGHGHETCPGAGRPAPAMMQQIKGLK
                     GCVANAWPYDEKGDYLGGPAVS"
     PFAM_domain     complement(32725..33222)
                     /aSDomain="DUF3152"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF11350.11"
                     /description="Protein of unknown function (DUF3152)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5313_0510"
                     /evalue="5.60E-35"
                     /label="SCO5313"
                     /locus_tag="SCO5313"
                     /protein_end="280"
                     /protein_start="114"
                     /score="121.0"
                     /tool="antismash"
                     /translation="IPATGPGTFVTARADGTTVGTGSRVRRYKVLVEKGIDVRPSAAAA
                     EISEVLADRRGWTQDGTNSFRLVSSGSYDFVVKIATPGTVDRICGAAGLLTRGEVNCSV
                     GTDVVVNLKRWVLGSPEFDGPIHEYRALIVNHEVGHRIGHGHETCPGAGRPAPAMMQQI
                     KGL"
     misc_feature    complement(32797..32826)
                     /gene_synonym="SC6G9.20"
                     /locus_tag="SCO5313"
                     /note="PS00142 Neutral zinc metallopeptidases, zinc-binding
                     region signature"
     regulatory      complement(33574..33577)
                     /note="possible RBS"
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(33788..39540)
                     /note="sequence corresponding to EMBL:X55942, S. coelicolor
                     whiE locus DNA"
     gene            complement(33809..34144)
                     /db_xref="GeneID:1100754"
                     /gene_synonym="SC6G9.19"
                     /locus_tag="SCO5314"
     CDS             complement(33809..34144)
                     /codon_start=1
                     /db_xref="GeneID:1100754"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225:Polyketide synthesis cyclase (Score: 156.4;
                     E-value: 3.6e-48)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C21/C2-C23|C2-C19 (Score: 154.8; E-value: 1.5e-48)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC6G9.19"
                     /locus_tag="SCO5314"
                     /note="SC6G9.19, whiE ORF VII, len: 111 aa; unknown
                     function, whiE locus protein previously sequenced from S.
                     coelicolor as SW:YW12_STRCO (EMBL:X55942)"
                     /product="whiE protein VII"
                     /protein_id="NP_629456.1"
                     /transl_table=11
                     /translation="MHHTLIVARMAPGAAPDIAKVFAESDSGELPHLVGVNRRSLFEFG
                     DGVYLHLIESDEDPAPTIGRLTGHPEFRQVSERLEPYVSAYDPATWRGPKDAMARCFYR
                     WERTPAG"
     PFAM_domain     complement(33827..34141)
                     /aSDomain="Cyclase_polyket"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04673.15"
                     /db_xref="GO:0030639"
                     /description="Polyketide synthesis cyclase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5314_0511"
                     /evalue="4.60E-44"
                     /gene_ontologies="GO:0030639: polyketide biosynthetic
                     process"
                     /label="SCO5314"
                     /locus_tag="SCO5314"
                     /protein_end="106"
                     /protein_start="1"
                     /score="149.1"
                     /tool="antismash"
                     /translation="HHTLIVARMAPGAAPDIAKVFAESDSGELPHLVGVNRRSLFEFGD
                     GVYLHLIESDEDPAPTIGRLTGHPEFRQVSERLEPYVSAYDPATWRGPKDAMARCFYRW
                     E"
     gene            complement(34178..34657)
                     /db_xref="GeneID:1100755"
                     /gene_synonym="SC6G9.18"
                     /locus_tag="SCO5315"
     CDS             complement(34178..34657)
                     /NRPS_PKS="Domain: Polyketide_cyc (10-135). E-value:
                     7.2e-16. Score: 50.5. Matches aSDomain:
                     nrpspksdomains_SCO5315_Polyketide_cyc.1"
                     /codon_start=1
                     /db_xref="GeneID:1100755"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 217.5; E-value:
                     4.4e-66)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C9-C14
                     (Score: 250.4; E-value: 1.1e-77)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC6G9.18"
                     /locus_tag="SCO5315"
                     /note="SC6G9.18, polyketide cyclase, len: 159 aa; whiE
                     locus polyketide cyclase previously sequenced from S.
                     coelicolor as SW:CYPC_STRCO (EMBL:X55942)"
                     /product="polyketide cyclase"
                     /protein_id="NP_629457.1"
                     /transl_table=11
                     /translation="MAGHTDNEITIAAPMELVWNMTNDIEKWPGLFSEYASVEVLGRDD
                     DKVTFRLTMHPDADGKVWSWVSERVADPVTRTVRAQRVETGPFQYMNIVWEYAETAEGT
                     VMRWTQDFAMKPDAPVDDAWMTDNINRNSRTQMALIRDRIEQAAGERRTASVLAD"
     aSDomain        complement(34253..34627)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5315_Polyketide_cyc.1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="7.20E-16"
                     /label="SCO5315_Polyketide_cyc.1"
                     /locus_tag="SCO5315"
                     /protein_end="135"
                     /protein_start="10"
                     /score="50.5"
                     /tool="antismash"
                     /translation="IAAPMELVWNMTNDIEKWPGLFSEYASVEVLGRDDDKVTFRLTMH
                     PDADGKVWSWVSERVADPVTRTVRAQRVETGPFQYMNIVWEYAETAEGTVMRWTQDFAM
                     KPDAPVDDAWMTDNINRNSRT"
     PFAM_domain     complement(34253..34627)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03364.23"
                     /description="Polyketide cyclase / dehydrase and lipid
                     transport"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5315_0512"
                     /evalue="2.50E-13"
                     /label="SCO5315"
                     /locus_tag="SCO5315"
                     /protein_end="135"
                     /protein_start="10"
                     /score="50.5"
                     /tool="antismash"
                     /translation="IAAPMELVWNMTNDIEKWPGLFSEYASVEVLGRDDDKVTFRLTMH
                     PDADGKVWSWVSERVADPVTRTVRAQRVETGPFQYMNIVWEYAETAEGTVMRWTQDFAM
                     KPDAPVDDAWMTDNINRNSRT"
     misc_feature    34652..34662
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.05"
                     /tool="antismash"
     gene            complement(34659..34931)
                     /db_xref="GeneID:1100756"
                     /gene_synonym="SC6G9.17"
                     /locus_tag="SCO5316"
     CDS             complement(34659..34931)
                     /NRPS_PKS="Domain: PP-binding (13-82). E-value: 1.5e-10.
                     Score: 33.4. Matches aSDomain:
                     nrpspksdomains_SCO5316_PP-binding.1"
                     /codon_start=1
                     /db_xref="GeneID:1100756"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 82.8; E-value:
                     2.3e-25)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 73.9; E-value: 1.8e-23)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC6G9.17"
                     /locus_tag="SCO5316"
                     /note="SC6G9.17, acyl carrier protein, len 90 aa; whiE
                     locus acyl carrier protein previously sequenced from
                     S.coelicolor as SW:ACP_STRCO (EMBL:X55942). Contains Pfam
                     match to entry PF00550 pp-binding, Phosphopantetheine
                     attachment site and PS00012 Phosphopantetheine attachment
                     site"
                     /product="acyl carrier protein"
                     /protein_id="NP_629458.1"
                     /sec_met_domain="PP-binding (E-value: 2.1e-08, bitscore:
                     33.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDQQLDYQVTVEELSALMKRTAGVHVDPVTLRQQADDGFDTFGL
                     DSLGLLGIVAELEKRYGLGLPEQAERCKTPADFLALVNGALKTGV"
     aSDomain        complement(34686..34892)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5316_PP-binding.1"
                     /evalue="1.50E-10"
                     /label="SCO5316_PP-binding.1"
                     /locus_tag="SCO5316"
                     /protein_end="82"
                     /protein_start="13"
                     /score="33.4"
                     /tool="antismash"
                     /translation="ELSALMKRTAGVHVDPVTLRQQADDGFDTFGLDSLGLLGIVAELE
                     KRYGLGLPEQAERCKTPADFLALV"
     PFAM_domain     complement(34686..34892)
                     /aSDomain="PP-binding"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00550.28"
                     /description="Phosphopantetheine attachment site"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5316_0513"
                     /evalue="7.70E-09"
                     /label="SCO5316"
                     /locus_tag="SCO5316"
                     /protein_end="82"
                     /protein_start="13"
                     /score="35.9"
                     /tool="antismash"
                     /translation="ELSALMKRTAGVHVDPVTLRQQADDGFDTFGLDSLGLLGIVAELE
                     KRYGLGLPEQAERCKTPADFLALV"
     misc_feature    complement(34686..34895)
                     /gene_synonym="SC6G9.17"
                     /locus_tag="SCO5316"
                     /note="Pfam match to entry PF00550 pp-binding,
                     Phosphopantetheine attachment site, score 44.90, E-value
                     8.6e-11"
     misc_feature    complement(34761..34808)
                     /gene_synonym="SC6G9.17"
                     /locus_tag="SCO5316"
                     /note="PS00012 Phosphopantetheine attachment site"
     gene            complement(35001..36275)
                     /db_xref="GeneID:1100757"
                     /gene_synonym="SC6G9.16"
                     /locus_tag="SCO5317"
     CDS             complement(35001..36275)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (62-415). E-value:
                     4.8e-27. Score: 86.7. Matches aSDomain:
                     nrpspksdomains_SCO5317_PKS_KS.1"
                     /codon_start=1
                     /db_xref="GeneID:1100757"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 585.5; E-value:
                     7.2e-178)"
                     /gene_functions="biosynthetic-additional (t2pks) CLF
                     (Score: 555.8; E-value: 1.2e-169)"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SC6G9.16"
                     /locus_tag="SCO5317"
                     /note="SC6G9.16, polyketide beta-ketoacyl synthase beta,
                     len: 424 aa; whiE locus polyketide beta-ketoacyl synthase
                     beta previously sequenced from S. coelicolor as
                     SW:KAS2_STRCO (EMBL:X55942). May form heterodimer with
                     SW:KAS1_STRCO, SC6G9.15 in beta-ketoacyl synthase
                     beta-ketoacyl synthase alpha. Similar to others from
                     S.coelicolor e.g. TR:O54149 (EMBL:AL021409) probable
                     3-oxoacyl-[acyl-carrier-protein] synthase (407 aa) (34.6%
                     identity in 405 aa overlap). Contains Pfam match to entry
                     PF00109 ketoacyl-synt, Beta-ketoacyl synthase"
                     /product="polyketide beta-ketoacyl synthase beta"
                     /protein_id="NP_629459.1"
                     /sec_met_domain="t2clf (E-value: 9.1e-140, bitscore: 464.7,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGPQRTGTGGGSRRAVVTGLGVLSPHGTGVEAHWKAVADGTSSL
                     GPVTREGCAHLPLRVAGEVHGFDAAETVEDRFLVQTDRFTHFALSATQHALADARFGRA
                     DVDSPYSVGVVTAAGSGGGEFGQRELQNLWGHGSRHVGPYQSIAWFYAASTGQVSIRND
                     FKGPCGVVAADEAGGLDALAHAALAVRNGTDTVVCGATEAPLAPYSIVCQLGYPELSRA
                     TEPDRAYRPFTEAACGFAPAEGGAVLVVEEEAAARERGADVRATVAGHAATFTGAGRWA
                     ESREGLARAIQGALAEAGCRPEEVDVVFADALGVPEADRAEALALADALGPHAARVPVT
                     APKTGTGRAYCAAPVLDVATAVLAMEHGLIPPTPHVLDVCHDLDLVTGRARPAEPRTAL
                     VLARGLMGSNSALVLRRGAVPPEGR"
     misc_feature    complement(35025..36230)
                     /gene_synonym="SC6G9.16"
                     /locus_tag="SCO5317"
                     /note="Pfam match to entry PF00109 ketoacyl-synt,
                     Beta-ketoacyl synthase, score -20.00, E-value 4.9e-11"
     aSDomain        complement(35031..36089)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5317_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="4.80E-27"
                     /label="SCO5317_PKS_KS.1"
                     /locus_tag="SCO5317"
                     /protein_end="415"
                     /protein_start="62"
                     /score="86.7"
                     /tool="antismash"
                     /translation="EVHGFDAAETVEDRFLVQTDRFTHFALSATQHALADARFGRADVD
                     SPYSVGVVTAAGSGGGEFGQRELQNLWGHGSRHVGPYQSIAWFYAASTGQVSIRNDFKG
                     PCGVVAADEAGGLDALAHAALAVRNGTDTVVCGATEAPLAPYSIVCQLGYPELSRATEP
                     DRAYRPFTEAACGFAPAEGGAVLVVEEEAAARERGADVRATVAGHAATFTGAGRWAESR
                     EGLARAIQGALAEAGCRPEEVDVVFADALGVPEADRAEALALADALGPHAARVPVTAPK
                     TGTGRAYCAAPVLDVATAVLAMEHGLIPPTPHVLDVCHDLDLVTGRARPAEPRTALVLA
                     RGLMGSNSALVLR"
     PFAM_domain     complement(35148..35483)
                     /aSDomain="Ketoacyl-synt_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02801.25"
                     /description="Beta-ketoacyl synthase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5317_0515"
                     /evalue="2.10E-24"
                     /label="SCO5317"
                     /locus_tag="SCO5317"
                     /protein_end="376"
                     /protein_start="264"
                     /score="85.9"
                     /tool="antismash"
                     /translation="ATVAGHAATFTGAGRWAESREGLARAIQGALAEAGCRPEEVDVVF
                     ADALGVPEADRAEALALADALGPHAARVPVTAPKTGTGRAYCAAPVLDVATAVLAMEHG
                     LIPPTPHV"
     PFAM_domain     complement(35511..36233)
                     /aSDomain="ketoacyl-synt"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00109.29"
                     /description="Beta-ketoacyl synthase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5317_0514"
                     /evalue="3.30E-30"
                     /label="SCO5317"
                     /locus_tag="SCO5317"
                     /protein_end="255"
                     /protein_start="14"
                     /score="105.6"
                     /tool="antismash"
                     /translation="RAVVTGLGVLSPHGTGVEAHWKAVADGTSSLGPVTREGCAHLPLR
                     VAGEVHGFDAAETVEDRFLVQTDRFTHFALSATQHALADARFGRADVDSPYSVGVVTAA
                     GSGGGEFGQRELQNLWGHGSRHVGPYQSIAWFYAASTGQVSIRNDFKGPCGVVAADEAG
                     GLDALAHAALAVRNGTDTVVCGATEAPLAPYSIVCQLGYPELSRATEPDRAYRPFTEAA
                     CGFAPAEGGAVLVVEEEAA"
     gene            complement(36272..37543)
                     /db_xref="GeneID:1100758"
                     /gene_synonym="SC6G9.15"
                     /locus_tag="SCO5318"
     CDS             complement(36272..37543)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (5-393). E-value:
                     6.5e-52. Score: 168.7. Matches aSDomain:
                     nrpspksdomains_SCO5318_PKS_KS.1"
                     /codon_start=1
                     /db_xref="GeneID:1100758"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 465.7; E-value:
                     2.4e-141)"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     712.5; E-value: 3.7e-217)"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SC6G9.15"
                     /locus_tag="SCO5318"
                     /note="SC6G9.15, polyketide beta-ketoacyl synthase alpha,
                     len: 423 aa; whiE locus polyketide beta-ketoacyl synthase
                     alpha previously sequenced from S. coelicolor as
                     SW:KAS1_STRCO (EMBL:X55942). May form heterodimer with
                     SW:KAS2_STRCO, SC6G9.16 beta-ketoacyl synthase beta.
                     Similar to others from S.coelicolor e.g. TR:O54149
                     (EMBL:AL021409) probable 3-oxoacyl-[acyl-carrier-protein]
                     synthase (407 aa) (39.1% identity in 419 aa overlap).
                     Contains Pfam match to entry PF00109 ketoacyl-synt,
                     Beta-ketoacyl synthase and PS00606 Beta-ketoacyl synthases
                     active site"
                     /product="polyketide beta-ketoacyl synthase alpha"
                     /protein_id="NP_629460.1"
                     /sec_met_domain="t2ks (E-value: 5.5e-205, bitscore: 680.0,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRRVAVTGIGVVAPGGIGTPQFWRLLSEGRTATRRISLFDPSG
                     LRSQIAAECDFEPSDHGLGLATAQRCDRYVQFALVAASEAVRDANLDMNREDPWRAGAT
                     LGTAVGGTTRLEHDYVLVSERGSRWDVDDRRSEPHLERAFTPATLSSAVAEEFGVRGPV
                     QTVSTGCTSGLDAVGYAYHAVAEGRVDVCLAGAADSPISPITMACFDAIKATSPNNDDP
                     AHASRPFDADRNGFVMGEGAAVLVLEDLEHARARGADVYCEVSGYATFGNAYHMTGLTK
                     EGLEMARAIDTALDMAELDGSAIDYVNAHGSGTQQNDRHETAAVKRSLGEHAYATPMSS
                     IKSMVGHSLGAIGSIELAACVLAMAHQVVPPTANYTTPDPECDLDYVPREARERTLRHV
                     LSVGSGFGGFQSAVVLSGSEGGLR"
     misc_feature    complement(36287..37528)
                     /gene_synonym="SC6G9.15"
                     /locus_tag="SCO5318"
                     /note="Pfam match to entry PF00109 ketoacyl-synt,
                     Beta-ketoacyl synthase, score 589.00, E-value 2.8e-173"
     aSDomain        complement(36365..37528)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5318_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="6.50E-52"
                     /label="SCO5318_PKS_KS.1"
                     /locus_tag="SCO5318"
                     /protein_end="393"
                     /protein_start="5"
                     /score="168.7"
                     /tool="antismash"
                     /translation="VAVTGIGVVAPGGIGTPQFWRLLSEGRTATRRISLFDPSGLRSQI
                     AAECDFEPSDHGLGLATAQRCDRYVQFALVAASEAVRDANLDMNREDPWRAGATLGTAV
                     GGTTRLEHDYVLVSERGSRWDVDDRRSEPHLERAFTPATLSSAVAEEFGVRGPVQTVST
                     GCTSGLDAVGYAYHAVAEGRVDVCLAGAADSPISPITMACFDAIKATSPNNDDPAHASR
                     PFDADRNGFVMGEGAAVLVLEDLEHARARGADVYCEVSGYATFGNAYHMTGLTKEGLEM
                     ARAIDTALDMAELDGSAIDYVNAHGSGTQQNDRHETAAVKRSLGEHAYATPMSSIKSMV
                     GHSLGAIGSIELAACVLAMAHQVVPPTANYTTPDPECDLDYVPREARE"
     PFAM_domain     complement(36419..36763)
                     /aSDomain="Ketoacyl-synt_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02801.25"
                     /description="Beta-ketoacyl synthase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5318_0517"
                     /evalue="3.70E-33"
                     /label="SCO5318"
                     /locus_tag="SCO5318"
                     /protein_end="375"
                     /protein_start="260"
                     /score="114.2"
                     /tool="antismash"
                     /translation="YCEVSGYATFGNAYHMTGLTKEGLEMARAIDTALDMAELDGSAID
                     YVNAHGSGTQQNDRHETAAVKRSLGEHAYATPMSSIKSMVGHSLGAIGSIELAACVLAM
                     AHQVVPPTANY"
     CDS_motif       complement(36749..36775)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5318_0002"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="SCO5318"
                     /protein_end="265"
                     /protein_start="256"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="GADVYCEVS"
     PFAM_domain     complement(36785..37534)
                     /aSDomain="ketoacyl-synt"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00109.29"
                     /description="Beta-ketoacyl synthase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5318_0516"
                     /evalue="4.00E-53"
                     /label="SCO5318"
                     /locus_tag="SCO5318"
                     /protein_end="253"
                     /protein_start="3"
                     /score="180.7"
                     /tool="antismash"
                     /translation="RRVAVTGIGVVAPGGIGTPQFWRLLSEGRTATRRISLFDPSGLRS
                     QIAAECDFEPSDHGLGLATAQRCDRYVQFALVAASEAVRDANLDMNREDPWRAGATLGT
                     AVGGTTRLEHDYVLVSERGSRWDVDDRRSEPHLERAFTPATLSSAVAEEFGVRGPVQTV
                     STGCTSGLDAVGYAYHAVAEGRVDVCLAGAADSPISPITMACFDAIKATSPNNDDPAHA
                     SRPFDADRNGFVMGEGAAVLVLEDLEHA"
     CDS_motif       complement(36821..36859)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5318_0001"
                     /evalue="6.90E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="SCO5318"
                     /protein_end="241"
                     /protein_start="228"
                     /score="9.8"
                     /tool="antismash"
                     /translation="FDADRNGFVMGEG"
     misc_feature    complement(37013..37063)
                     /gene_synonym="SC6G9.15"
                     /locus_tag="SCO5318"
                     /note="PS00606 Beta-ketoacyl synthases active site"
     gene            complement(37540..38013)
                     /db_xref="GeneID:1100759"
                     /gene_synonym="SC6G9.14"
                     /locus_tag="SCO5319"
     CDS             complement(37540..38013)
                     /codon_start=1
                     /db_xref="GeneID:1100759"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C5-C18
                     (Score: 218.4; E-value: 5.6e-68)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC6G9.14"
                     /locus_tag="SCO5319"
                     /note="SC6G9.14, whiE ORF II, len: 157 aa; unknown
                     function, whiE locus protein previously sequenced from S.
                     coelicolor as SW:WH16_STRCO (EMBL:X55942)"
                     /product="whiE protein II"
                     /protein_id="NP_629461.1"
                     /transl_table=11
                     /translation="MTDQQVRIVSLGDIAPNRRRGGDLRALLTPTTAGSTSGFMGVAIV
                     QPGDRIAEHYHPYSEEFVYVTEGALEVDLDGVPHSLGTGQGLLIPQDMRHRFRNAGDVE
                     ARLVFHLGPLAPRPELGHVDTEDAEGNALPCDGAHAGHAAGHERPAPAAEVVS"
     PFAM_domain     complement(37690..37890)
                     /aSDomain="Cupin_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07883.14"
                     /description="Cupin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5319_0518"
                     /evalue="3.00E-19"
                     /label="SCO5319"
                     /locus_tag="SCO5319"
                     /protein_end="108"
                     /protein_start="41"
                     /score="68.6"
                     /tool="antismash"
                     /translation="VAIVQPGDRIAEHYHPYSEEFVYVTEGALEVDLDGVPHSLGTGQG
                     LLIPQDMRHRFRNAGDVEARLV"
     gene            complement(38160..39353)
                     /db_xref="GeneID:1100760"
                     /gene_synonym="SC6G9.13"
                     /locus_tag="SCO5320"
     CDS             complement(38160..39353)
                     /codon_start=1
                     /db_xref="GeneID:1100760"
                     /gene_synonym="SC6G9.13"
                     /locus_tag="SCO5320"
                     /note="SC6G9.13, whiE ORF I, len: 397 aa; unknown function,
                     whiE locus protein previously sequenced from S. coelicolor
                     as SW:WH42_STRCO (EMBL:X55942)"
                     /product="whiE protein I"
                     /protein_id="NP_629462.1"
                     /transl_table=11
                     /translation="MTVSPVVATDAPSTDATRTTATSATSPAVATDAGGVSISAFDGSR
                     VRVVLMLDVHDGMQQEFLDAYERIRDRVAAVPGHVSDQLCQSLENPTQWLLTSEWESAA
                     PFLAWVNSDEHLDTVEPLATCVRDTHSLRYSVLRETDGGRPAPGEPRSAPRIGDNVVRH
                     ALTFTVRPGTEAETARLLSEYVSPDAHVDGSTRLLRTSLFMSGNRIVRAVEVRGDLQTA
                     LRHVARQPGVRAVEEALNPYLEQDRDLGDPQSARRFFTRAAMPAVHHATYPDRSGARRE
                     RLALLYPVRDGAGPDLARLLARQDAAAARNPDGPVLAATVFHRDDLVVRLVDVDGDPED
                     APAEVLGLHGRGAADAERLLDAAAVGVDGSPAEAATLSRLLRRIRMTPLTDRRSAGS"
     PFAM_domain     complement(38541..38876)
                     /aSDomain="SchA_CurD"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04486.15"
                     /description="SchA/CurD like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5320_0520"
                     /evalue="6.40E-46"
                     /label="SCO5320"
                     /locus_tag="SCO5320"
                     /protein_end="271"
                     /protein_start="159"
                     /score="155.5"
                     /tool="antismash"
                     /translation="VVRHALTFTVRPGTEAETARLLSEYVSPDAHVDGSTRLLRTSLFM
                     SGNRIVRAVEVRGDLQTALRHVARQPGVRAVEEALNPYLEQDRDLGDPQSARRFFTRAA
                     MPAVHHAT"
     PFAM_domain     complement(38994..39218)
                     /aSDomain="ABM"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03992.19"
                     /description="Antibiotic biosynthesis monooxygenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5320_0519"
                     /evalue="2.20E-16"
                     /label="SCO5320"
                     /locus_tag="SCO5320"
                     /protein_end="120"
                     /protein_start="45"
                     /score="59.9"
                     /tool="antismash"
                     /translation="VRVVLMLDVHDGMQQEFLDAYERIRDRVAAVPGHVSDQLCQSLEN
                     PTQWLLTSEWESAAPFLAWVNSDEHLDTVE"
     misc_feature    39546..40463
                     /note="sequence corresponding to EMBL:X74213, S.coelicolor
                     gene for aromatic hydroxylase"
     regulatory      39685..39689
                     /note="possible RBS"
                     /regulatory_class="ribosome_binding_site"
     gene            39697..41580
                     /db_xref="GeneID:1100761"
                     /gene_synonym="SC6G9.12c"
                     /locus_tag="SCO5321"
     CDS             39697..41580
                     /codon_start=1
                     /db_xref="GeneID:1100761"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 575; E-value:
                     2.6e-174)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 243.9; E-value: 8.1e-75)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC6G9.12c"
                     /locus_tag="SCO5321"
                     /note="SC6G9.12c, polyketide hydroxylase, len: 627 aa;
                     previously partially sequenced from S.coelicolor as
                     SW:HYDL_STRCO (EMBL:X74213). Highly similar to
                     SW:HYDL_STRHA (EMBL:L05390), schC, Streptomyces halstedii
                     polyketide hydroxylase involved in synthesis of a
                     polyketide spore pigment (555 aa), fasta scores; opt: 2290
                     z-score: 1755.0 E(): 0, 69.2% identity in 629 aa overlap.
                     Also similar to many hydroxylases of substitued aromatic
                     compounds. A notable difference between this sequence and
                     its Streptomyces halstedii homologue is the presence of 12x
                     GGP repeats starting at aa 413. Weakly similar to TR:O50491
                     (EMBL:AL020958) S.coelicolor possible monooxygenase (541
                     aa) (29.2% identity in 583 aa overlap). This feature is
                     also absent from the other related hydroxylases. Contains
                     Pfam match to entry PF01360 Monooxygenase, Monooxygenase.
                     Contains possible hydrophobic membrane spanning region"
                     /product="polyketide hydroxylase"
                     /protein_id="NP_629463.1"
                     /transl_table=11
                     /translation="MNERADRSGGAAPGGDRTHRVPVLVVGGSLVGLSTSVFLGRLGVR
                     HTLVERHAGTSIHPRGRGNNVRTMEIFRVAGTEPDIRRAAATLADNHGILQAPTLAGDA
                     GEWLFKQIDPGGGLARFSPSSWCLCSQNDLEPELLTHATNLGGDLRFGTELLSFEADTE
                     GVTAIVKSRETGEHTTIRADYLVAADGPRSPVREQLGIGQSGPGDLFHNVSITFRSRRL
                     ADVVGDRRFIVCYLTDENADGALLPVDNRENWVFHAPWHPEQGETVEDFTDERCAAHIR
                     RAIGDPDLDVEITGKAPWHAAQRVARSYRSGRVLLAGDSAHEMSPTGAFGSNTGIQDAH
                     NLAWKLAAVLEGWAGEALLDTYDTERRPVAEATSARAAHRSVEHSHPGFAPPPVAGGGG
                     PGAGTPGGAGRGTGGPGGPGGPGGLGGPGGPGGTGGPGGPGGPGGPDGPRGAGGAPGGG
                     PGGGPGGGGPQRGILNVALGYRYPRGAVVGADPATPVVPEGLDLTGAPGSRAPHLWVRR
                     GQDRLSTLDLYEDSLVLLSDAAQPTGWHEAAAGVAAGMRVPLKSYRVGGSPGADLNPDD
                     EETDWARAHGVTRGGAVLVRPDGFVAWRSPGPAPDPESMLRQVVGTVLARS"
     PFAM_domain     39757..40821
                     /aSDomain="FAD_binding_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01494.22"
                     /db_xref="GO:0071949"
                     /description="FAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5321_0521"
                     /evalue="6.50E-111"
                     /gene_ontologies="GO:0071949: FAD binding"
                     /label="SCO5321"
                     /locus_tag="SCO5321"
                     /protein_end="375"
                     /protein_start="20"
                     /score="371.1"
                     /tool="antismash"
                     /translation="VPVLVVGGSLVGLSTSVFLGRLGVRHTLVERHAGTSIHPRGRGNN
                     VRTMEIFRVAGTEPDIRRAAATLADNHGILQAPTLAGDAGEWLFKQIDPGGGLARFSPS
                     SWCLCSQNDLEPELLTHATNLGGDLRFGTELLSFEADTEGVTAIVKSRETGEHTTIRAD
                     YLVAADGPRSPVREQLGIGQSGPGDLFHNVSITFRSRRLADVVGDRRFIVCYLTDENAD
                     GALLPVDNRENWVFHAPWHPEQGETVEDFTDERCAAHIRRAIGDPDLDVEITGKAPWHA
                     AQRVARSYRSGRVLLAGDSAHEMSPTGAFGSNTGIQDAHNLAWKLAAVLEGWAGEALLD
                     TYDTERRPVAEATSA"
     misc_feature    40237..40830
                     /gene_synonym="SC6G9.12c"
                     /locus_tag="SCO5321"
                     /note="Pfam match to entry PF01360 Monooxygenase,
                     Monooxygenase, score 233.10, E-value 3.9e-66"
     repeat_region   40933..41040
                     /gene_synonym="SC6G9.12c"
                     /locus_tag="SCO5321"
                     /note="repeat 2; 12x degenerate 12 bp repeats"
     gene            41657..42526
                     /db_xref="GeneID:1100762"
                     /gene_synonym="SC6G9.11c"
                     /locus_tag="SCO5322"
     CDS             41657..42526
                     /codon_start=1
                     /db_xref="GeneID:1100762"
                     /gene_synonym="SC6G9.11c"
                     /locus_tag="SCO5322"
                     /note="SC6G9.11c, conserved hypothetical protein, len: 289
                     aa; unknown function, similar to TR:O53410 (EMBL:AL021897)
                     Mycobacterium tuberculosis hypothetical protein (285 aa),
                     fasta scores; opt: 556 z-score: 639.1 E(): 2.9e-28, 38.8%
                     identity in 286 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_629464.1"
                     /transl_table=11
                     /translation="MVPVTGGVTDVADTALVLGGGGLTAYGWQIGVLAGLADAGVDLAD
                     ADVLAGTSAGSLLALDLARGAAPAGLYKEQLDRERPMLDVDFTFGMTVRYLWAALGSRD
                     PETVVRRLGRLALSVRDVPQSAVFAAIGAQLPVRDWPDRTVRMFAVDALTGEPTAFDAD
                     SGVDLLHAMSATCALPPLFPPISIGAGRWMDGGVRSTTNADLVDDCARVVVLAPIPKGA
                     GASPSARTQAETLASRGARVALLTPDRAARRAFGRNALDASRIPGAAREGRRQGAAHAG
                     RIGEIWQG"
     PFAM_domain     41702..42274
                     /aSDomain="Patatin"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01734.25"
                     /db_xref="GO:0006629"
                     /description="Patatin-like phospholipase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5322_0522"
                     /evalue="6.10E-16"
                     /gene_ontologies="GO:0006629: lipid metabolic process"
                     /label="SCO5322"
                     /locus_tag="SCO5322"
                     /protein_end="206"
                     /protein_start="15"
                     /score="59.3"
                     /tool="antismash"
                     /translation="LVLGGGGLTAYGWQIGVLAGLADAGVDLADADVLAGTSAGSLLAL
                     DLARGAAPAGLYKEQLDRERPMLDVDFTFGMTVRYLWAALGSRDPETVVRRLGRLALSV
                     RDVPQSAVFAAIGAQLPVRDWPDRTVRMFAVDALTGEPTAFDADSGVDLLHAMSATCAL
                     PPLFPPISIGAGRWMDGGVRSTTNADLV"
     gene            complement(42584..43078)
                     /db_xref="GeneID:1100763"
                     /gene_synonym="SC6G9.10"
                     /locus_tag="SCO5323"
     CDS             complement(42584..43078)
                     /codon_start=1
                     /db_xref="GeneID:1100763"
                     /gene_functions="regulatory (smcogs) SMCOG1120:AsnC family
                     transcriptional regulator (Score: 144.6; E-value: 2.8e-44)"
                     /gene_kind="regulatory"
                     /gene_synonym="SC6G9.10"
                     /locus_tag="SCO5323"
                     /note="SC6G9.10, probable Asn-C family transcriptional
                     regulator, len: 164 aa; similar to many e.g. TR:P94329
                     (EMBL:U85623), Lrp, Bradyrhizobium japonicum
                     leucine-responsive regulatory protein (153 aa), fasta
                     scores; opt: 211 z-score: 261.3 E(): 3.2e-07, 30.8%
                     identity in 143 aa overlap. Similar to others from
                     S.coelicolor e.g. (EMBL:AL049628), SCE94.12c, LrpA,
                     probable AsnC-family transcriptional regulator (150 aa)
                     (28.0% identity in 150 aa overlap). Contains probable
                     helix-turn-helix motif at aa 24-45 (Score 1012, +2.63 SD).
                     Contains Pfam match to entry PF01037 ASNC_trans_reg, AsnC
                     family"
                     /product="transcription regulator AsnC"
                     /protein_id="NP_629465.1"
                     /transl_table=11
                     /translation="MARQGLDQLDGRMLRLLRERPREGLLEIARRLGVARGTLQARLDR
                     LTGSGVVTGYGPDMDVAALGHVVQAFTTFEVDQPAREAIAARLRAVPQILEAHVVTGPG
                     DIWCRIAGTSNQHVQEVIDQVLEVPGVRRSTTVIALSAVVPYRVQPLVDEVSGLSEPRL
                     G"
     PFAM_domain     complement(42656..42856)
                     /aSDomain="AsnC_trans_reg"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01037.24"
                     /description="Lrp/AsnC ligand binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5323_0524"
                     /evalue="4.90E-14"
                     /label="SCO5323"
                     /locus_tag="SCO5323"
                     /protein_end="141"
                     /protein_start="74"
                     /score="52.2"
                     /tool="antismash"
                     /translation="EVDQPAREAIAARLRAVPQILEAHVVTGPGDIWCRIAGTSNQHVQ
                     EVIDQVLEVPGVRRSTTVIALS"
     misc_feature    complement(42692..42991)
                     /gene_synonym="SC6G9.10"
                     /locus_tag="SCO5323"
                     /note="Pfam match to entry PF01037 ASNC_trans_reg, AsnC
                     family, score 29.60, E-value 1.8e-06"
     PFAM_domain     complement(42920..43063)
                     /aSDomain="HTH_24"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13412.9"
                     /description="Winged helix-turn-helix DNA-binding"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5323_0523"
                     /evalue="8.60E-08"
                     /label="SCO5323"
                     /locus_tag="SCO5323"
                     /protein_end="53"
                     /protein_start="5"
                     /score="31.7"
                     /tool="antismash"
                     /translation="LDQLDGRMLRLLRERPREGLLEIARRLGVARGTLQARLDRLTGSG
                     VVT"
     regulatory      43201..43206
                     /note="possible RBS"
                     /regulatory_class="ribosome_binding_site"
     gene            43213..43893
                     /db_xref="GeneID:1100764"
                     /gene_synonym="SC6G9.09c"
                     /locus_tag="SCO5324"
     CDS             43213..43893
                     /codon_start=1
                     /db_xref="GeneID:1100764"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SC6G9.09c"
                     /locus_tag="SCO5324"
                     /note="SC6G9.09c, possible oxidoreductase, len: 226 aa;
                     weak similarity to SW:NOX_THETH (EMBL:X60110) Thermus
                     aquaticus NADH dehydrogenase (205 aa), fasta scores; opt:
                     159 z-score: 201.0 E(): 0.00073, 26.7% identity in 191 aa
                     overlap. Similar to TR:O75989 (EMBL:AL031010) Homo sapiens
                     hypothetical protein (184 aa) (40.0% identity in 185 aa
                     overlap) and to part of SW:YKH5_CAEEL (EMBL:L23649)
                     Caenorhabditis elegans hypothetical protein (359 aa) (28.6%
                     identity in 185 aa overlap). Weak similarity to
                     SW:NOX_THETH (EMBL:X60110) Thermus aquaticus NADH
                     dehydrogenase (205 aa) (26.7% identity in 191 aa overlap).
                     Contains Pfam match to entry PF00881 Nitroreductase,
                     Nitroreductase family"
                     /product="oxidoreductase"
                     /protein_id="NP_629466.1"
                     /sec_met_domain="PF00881 (E-value: 6.5e-23, bitscore: 80.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQHTHPFVPYRPDRYDEAEMIRRGRDFVSFVDRRRSVRFFSDEP
                     VPRECLDLAVAAANTAPSGAHFQPWKFAVIGDAATKHRIRVAAEEEERVNYEGGRIPPE
                     WRAALARLETDSDKGFLDVVPWIVVCFAEKSTALPDGSLRKNYYVNESVGIACGLFITA
                     LHAMGLSTLTHTPNPMAFLTRICARPGNERPYILFPVGYAAPDCEVPDLARKPLAEAIT
                     EPPR"
     misc_feature    43291..43779
                     /gene_synonym="SC6G9.09c"
                     /locus_tag="SCO5324"
                     /note="Pfam match to entry PF00881 Nitroreductase,
                     Nitroreductase family, score 20.60, E-value 0.00026"
     PFAM_domain     43309..43818
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00881.27"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5324_0525"
                     /evalue="1.10E-22"
                     /label="SCO5324"
                     /locus_tag="SCO5324"
                     /protein_end="202"
                     /protein_start="32"
                     /score="81.0"
                     /tool="antismash"
                     /translation="DRRRSVRFFSDEPVPRECLDLAVAAANTAPSGAHFQPWKFAVIGD
                     AATKHRIRVAAEEEERVNYEGGRIPPEWRAALARLETDSDKGFLDVVPWIVVCFAEKST
                     ALPDGSLRKNYYVNESVGIACGLFITALHAMGLSTLTHTPNPMAFLTRICARPGNERPY
                     ILFPVGY"
     misc_feature    43943..43961
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            44109..44429
                     /db_xref="GeneID:1100765"
                     /gene_synonym="SC6G9.08c"
                     /locus_tag="SCO5325"
     CDS             44109..44429
                     /codon_start=1
                     /db_xref="GeneID:1100765"
                     /gene_synonym="SC6G9.08c"
                     /locus_tag="SCO5325"
                     /note="SC6G9.08c, hypothetical protein, len: 106 aa;
                     unknown function, improbable CD suggested by GC frameplot.
                     C-terminus is proline-rich and overlaps with hypothetical
                     CDS on opposite strand"
                     /product="hypothetical protein"
                     /protein_id="NP_629467.1"
                     /transl_table=11
                     /translation="MEITLAALQGRWTTLVIRELLRGDHSYSDLRAALAAPSDKVTKVA
                     ADVITRWSSARARASQPVTARSRRTALASPPPSRTRAPPGTAGDRLTSPRPRRVRARPR
                     RH"
     gene            complement(44380..44634)
                     /db_xref="GeneID:1100766"
                     /gene_synonym="SC6G9.07"
                     /locus_tag="SCO5326"
     CDS             complement(44380..44634)
                     /codon_start=1
                     /db_xref="GeneID:1100766"
                     /gene_synonym="SC6G9.07"
                     /locus_tag="SCO5326"
                     /note="SC6G9.07, hypothetical protein, len: 54 aa; unknown
                     function, possible CDS suggested by GC frameplot,
                     positional base preference and amino acid composition.
                     Similar to part of (EMBL:AL049573), SCE39.23, S.coelicolor
                     hypothetical protein (88 aa), fasta scores; opt: 165
                     z-score: 222.7 E(): 4.4e-05, 46.7% identity in 60 aa
                     overlap. C-terminus overlaps with hypothetical CDS on
                     opposite strand"
                     /product="hypothetical protein"
                     /protein_id="NP_629468.1"
                     /transl_table=11
                     /translation="MGPDRSGLVAHRSFGRMDSSSEPTGKYSITMPRDIAEAAKARSGP
                     SGLSAYVAAAAARQIERDNLSELISVAEAEHGPVSDEET"
     misc_feature    complement(44607..55106)
                     /note="region of low %G+C content (average 61%)"
     repeat_region   44670..44691
                     /note="degenerate 22 bp inverted repeat (6 mismatches)"
     repeat_region   44670..45544
                     /note="repeat 1; insertion element IS1651, 875 bp imperfect
                     inverted repeat"
     gene            44792..45535
                     /db_xref="GeneID:1100767"
                     /gene_synonym="SC6G9.06c"
                     /locus_tag="SCO5327"
     CDS             44792..45535
                     /codon_start=1
                     /db_xref="GeneID:1100767"
                     /gene_synonym="SC6G9.06c"
                     /locus_tag="SCO5327"
                     /note="SC6G9.06c, possible transposase, len: 247 aa;
                     similar to TR:Q48342 (EMBL:M28508) Streptomyces lividans
                     ORFA from insertion element IS493 (254 aa), fasta scores;
                     opt: 585 z-score: 725.3 E(): 4.5e-33, 45.0% identity in 220
                     aa overlap. Contains probable helix-turn-helix motif at aa
                     49-70 (Score 1540, +4.43 SD)"
                     /product="transposase"
                     /protein_id="NP_629469.1"
                     /transl_table=11
                     /translation="MHPAALDLPHALVEWATMLIVTREGDRRCKLRPSQRAMVALVYLR
                     EHTTLAKIAAGFGISESTAHAYTRAVVDLLAACAPGLLKTLRDHEPDFVLLDGTLAECD
                     RVGDGRADYSHKHRRHGVNVQVVTDPGGRLLWLSPALPGRTHDLTAARTHRIIRICERQ
                     GVPIVADLAYQGAGPWLTTGIKRKPLQELTPTDKTRNRALAAARAPVERGVARLKSWRI
                     FRRSRCSPNRMTSIAKAVLTLELHR"
     PFAM_domain     44876..45031
                     /aSDomain="HTH_Tnp_4"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13613.9"
                     /description="Helix-turn-helix of DDE superfamily
                     endonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5327_0526"
                     /evalue="8.20E-15"
                     /label="SCO5327"
                     /locus_tag="SCO5327"
                     /protein_end="80"
                     /protein_start="28"
                     /score="54.4"
                     /tool="antismash"
                     /translation="CKLRPSQRAMVALVYLREHTTLAKIAAGFGISESTAHAYTRAVVD
                     LLAACAP"
     PFAM_domain     45077..45514
                     /aSDomain="DDE_Tnp_4"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13359.9"
                     /description="DDE superfamily endonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5327_0527"
                     /evalue="7.10E-28"
                     /label="SCO5327"
                     /locus_tag="SCO5327"
                     /protein_end="241"
                     /protein_start="95"
                     /score="97.4"
                     /tool="antismash"
                     /translation="LDGTLAECDRVGDGRADYSHKHRRHGVNVQVVTDPGGRLLWLSPA
                     LPGRTHDLTAARTHRIIRICERQGVPIVADLAYQGAGPWLTTGIKRKPLQELTPTDKTR
                     NRALAAARAPVERGVARLKSWRIFRRSRCSPNRMTSIAKAVL"
     repeat_region   complement(45523..45544)
                     /note="degenerate 22 bp inverted repeat (6 mismatches)"
     gene            complement(45664..45733)
                     /db_xref="GeneID:3240057"
                     /locus_tag="SCOt54"
     tRNA            complement(45664..45733)
                     /db_xref="GeneID:3240057"
                     /locus_tag="SCOt54"
                     /note="tRNA Pseudo anticodon CCG, Cove score 20.64"
                     /product="tRNA-OTHER"
     repeat_region   45873..45898
                     /note="degenerate 26 bp inverted repeat (8 mismatches)"
     repeat_region   complement(45873..46747)
                     /note="repeat 1; insertion element IS1651, 875 bp imperfect
                     inverted repeat"
     gene            complement(45885..46629)
                     /db_xref="GeneID:1100768"
                     /gene_synonym="SC6G9.05"
                     /locus_tag="SCO5328"
                     /pseudo=""
     misc_feature    complement(45885..46629)
                     /gene_synonym="SC6G9.05"
                     /locus_tag="SCO5328"
                     /note="SC6G9.05, possible transposase pseudogene, len: 745
                     bp; similar to TR:Q48342 (EMBL:M28508) Streptomyces
                     lividans ORFA from insertion element IS493 (254
                     aa);transposase pseudogene"
                     /pseudo=""
     repeat_region   complement(46722..46747)
                     /note="degenerate 26 bp inverted repeat (8 mismatches)"
     gene            46829..48526
                     /db_xref="GeneID:1100769"
                     /gene_synonym="SC6G9.04c"
                     /locus_tag="SCO5329"
     CDS             46829..48526
                     /codon_start=1
                     /db_xref="GeneID:1100769"
                     /gene_synonym="SC6G9.04c"
                     /locus_tag="SCO5329"
                     /note="SC6G9.04c, hypothetical protein, len: 565 aa;
                     similar to TR:O34810 (EMBL:AE000641) Helicobacter pylori
                     hypothetical protein (578 aa), fasta scores; opt: 391
                     z-score: 464.1 E(): 1.6e-18, 23.6% identity in 525 aa
                     overlap and to several other hypothetical proteins from the
                     same organism, with the highest similarity toward the
                     N-terminus. The coding sequence has unusually low %G+C
                     content"
                     /product="hypothetical protein"
                     /protein_id="NP_629470.1"
                     /transl_table=11
                     /translation="MSMIYEPAKKTVGDLLGDVAKKTSVPDYQRDYSWTESHVDYFWQD
                     VLGFMREQNEKTLADAEYFIGSMVRVDKAERYELLDGQQRLATIVILLSAIRDRLRPLN
                     TKAYIKTQGRWIAEEDDLTGESKYSLTLSTYDRDYFRRRIQNDPVETLKPATASQTLID
                     AARRKFDAELTSELDKQPDEKGREQWLLLLRDVIMNHVTTVTVTCASEQDAASIFETLN
                     DRGLGLSTVDLLRNFVLRRAGEPDRDEIVSIWADVLRESNSVDVDEFLRHYWISRHGDI
                     KSQRLYRAIRKYMEDSGESSLEFMRDLGSAHAAYVRLMRPDFANDATNEELQNIADLKA
                     KMLYPFLLSGLTRDEEGFLSLVRAGIVFYVREGIVVKRNSSQMEKVVFSAARLMSEGGA
                     TDKALALLHNGASADPVFDAAVRELRNLDTSAARYLLREIEISLRNGEETDVARPPKIH
                     IEHIYPQKPKAGERWSNHTDYVGKIGNLTLLARRINTAIKNSEFAVKRLELAKSEIFLT
                     REVAAHGMWDAAAIDQRQDELGKKVKSLWGWPPDVIEAVNKFPTHVEA"
     PFAM_domain     46865..47542
                     /aSDomain="DUF262"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03235.17"
                     /description="Protein of unknown function DUF262"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5329_0528"
                     /evalue="2.40E-33"
                     /label="SCO5329"
                     /locus_tag="SCO5329"
                     /protein_end="238"
                     /protein_start="12"
                     /score="116.3"
                     /tool="antismash"
                     /translation="GDLLGDVAKKTSVPDYQRDYSWTESHVDYFWQDVLGFMREQNEKT
                     LADAEYFIGSMVRVDKAERYELLDGQQRLATIVILLSAIRDRLRPLNTKAYIKTQGRWI
                     AEEDDLTGESKYSLTLSTYDRDYFRRRIQNDPVETLKPATASQTLIDAARRKFDAELTS
                     ELDKQPDEKGREQWLLLLRDVIMNHVTTVTVTCASEQDAASIFETLNDRGLGLSTVDLL
                     RNFV"
     PFAM_domain     48107..48448
                     /aSDomain="DUF1524"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07510.14"
                     /description="Protein of unknown function (DUF1524)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5329_0529"
                     /evalue="4.60E-27"
                     /label="SCO5329"
                     /locus_tag="SCO5329"
                     /protein_end="540"
                     /protein_start="426"
                     /score="94.7"
                     /tool="antismash"
                     /translation="LDTSAARYLLREIEISLRNGEETDVARPPKIHIEHIYPQKPKAGE
                     RWSNHTDYVGKIGNLTLLARRINTAIKNSEFAVKRLELAKSEIFLTREVAAHGMWDAAA
                     IDQRQDELGK"
     regulatory      48980..48983
                     /note="possible RBS"
                     /regulatory_class="ribosome_binding_site"
     gene            48989..49891
                     /db_xref="GeneID:1100770"
                     /gene_synonym="SC6G9.03c"
                     /locus_tag="SCO5330"
     CDS             48989..49891
                     /codon_start=1
                     /db_xref="GeneID:1100770"
                     /gene_synonym="SC6G9.03c"
                     /locus_tag="SCO5330"
                     /note="SC6G9.03c, hypothetical protein, len: 300 aa;
                     unknown function, probable CDS suggested by GC frameplot,
                     positional base preference and amino acid composition"
                     /product="hypothetical protein"
                     /protein_id="NP_629471.1"
                     /transl_table=11
                     /translation="MPKTAHIYVPSPSRENLEIGLDQGLWGWRRSALDRAGTRQAVQSL
                     TEGDFLVLGHRGPNSRVAPGGWANATLQRVIVTQVSRPYFTDSTPVWPGDDYPERIGID
                     VLEEEQNVPGTALGTDAMEALRLSANKQGAAVLQPGIAAVAQLADVLPLVPVLPGDATV
                     DHEGTDSAVAQVLVRREQVKLRKNLLGGATEAACALCGRVLPTRFIRAAHIKRRSAASR
                     QERLMMANIMPACLIGCDELFEHGYLYVTDNGTIAVSPKSNATPDLAVAAKALEGRTVA
                     DYGPHRAPFYIWHRTHIAN"
     gene            complement(50054..53656)
                     /db_xref="GeneID:1100771"
                     /gene_synonym="SC6G9.02"
                     /locus_tag="SCO5331"
     CDS             complement(50054..53656)
                     /codon_start=1
                     /db_xref="GeneID:1100771"
                     /gene_synonym="SC6G9.02"
                     /locus_tag="SCO5331"
                     /note="SC6G9.02, possible DNA methylase, len: 1200 aa;
                     highly similar to TR:O86561 (EMBL:AL031350) (71.5% identity
                     in 867 aa overlap) and TR:O86674 (EMBL:AL031371) (90.8%
                     identity in 370 aa overlap) which together constitute a
                     single hypothetical protein split across the join between
                     S.coelicolor cosmids 1F2 and 4G2. It has very weak
                     similarity to DNA methylases, which combined with the
                     presence of a DNA methylases signature and possible
                     DNA-binding region (helix-turn-helix) provides
                     circumstantial evidence of DNA-methylase function. The
                     central third of the CDS is relatively AT rich. Contains
                     probable helix-turn-helix motif at aa 38-59 (Score 1036,
                     +2.72 SD). Contains PS00092 N-6 Adenine-specific DNA
                     methylases signature"
                     /product="DNA methylase"
                     /protein_id="NP_629472.1"
                     /transl_table=11
                     /translation="MIDRKALLDHLKQQVKAVEADLGKQVKPLGEAGARLRTEYDQARK
                     LGRTAATWNSWLDERVTQVAVAWVLGTVFVRFCEDNRLIPEPYLTGPDGDRRELAEARY
                     DAYVESDDDPTYRGWLEKAFDELGQGQAGRLLFDKRHNPLYQIPLSHDGARELVEFWRQ
                     RDEAGVLVHDFTDPLNEDGTEGWDTRFLGDLYQDLSEAARKTYALLQTPEFVEEFILDR
                     TMNPAVREFGYEELKMIDPTCGSGHFVLGAFRRLVRLWAEGQPGRDVHERVRAALHSIH
                     GVDINPFAVAIARFRLLVAAIAASGVRTLAEAAKYEWPIHLAVGDSLIKARQLELTLGG
                     DEDGGYDPLASFTYATEDVHEHPGILQQGRYHVVVGNPPYITVKDKKLNELYRELYDAC
                     GGTYALSVPFAQRFFELAKRGGDEGRAYGMVGQITANSFMKREFGTKLIERYFRDRVEL
                     TEVIDTSGAYIPGHGTPTVILVGKRCKGSQRLSTIRTVRSIQGEPAAPANGKDGLVWNA
                     IVDQIDKPGSVSQWVSVDDLERGRYFAKQPWILANGGLEMVEQLSKSAIKIIGSLSDAI
                     GRTTHTGMDDCFYMKASAAKTLALSDSCVPVVPGDGIRDFGINSRLSTYFPYDSRGNPR
                     EITLPEYRFLWPNRTVLRRRLDFGQTPTERGLRWFDHSMFFPKRYSTPLGIAFPFVATH
                     SHFSLDRGGKVFNRTAPVIKLQEGASEEEHLQLLGLLNSSTAGFWLKQVSHDKGIRGEG
                     GGFTSDDWERFFEFTGTKLQEFPLPAEHPTTLATTLDALAQQLSAISPEAVAVEAAPVA
                     SALREAKVRWESIRARMIALQEELDWQVYSLYNLHSEDLRVSEDPDDPNIPELALGERA
                     FEIVLARRVAAGEASDEWFKRHNSTPNTEVPAHWPASYREVVQKRIDAIESNRAIGMVE
                     RPEYKRRWATEGWDALQEKALRSWLLDHMEDRDLWFDENGQPTILTLARLTDALSRDED
                     FVSVAKLYAPRQDMHKVVAELITDEHVPFLSALRYKPSGLKKHADWEEVWDLQRKEDAA
                     PDEPAKRKIRDSIPVPPKYASADFLRPSYWRARGKLDVPKERFISYGQTNAATPELYGW
                     AGWDHKEQAQALATYFTNTALTTEEITPFLAGLLELQPWLYQWHNGFDMLYSGPPADFF
                     ASYRQQKQAEHGLTDDHLRAWRPSASTRGKDKKR"
     PFAM_domain     complement(52505..52954)
                     /aSDomain="MmeI_Mtase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF20473.1"
                     /description="MmeI, DNA-methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5331_0530"
                     /evalue="1.50E-08"
                     /label="SCO5331"
                     /locus_tag="SCO5331"
                     /protein_end="384"
                     /protein_start="234"
                     /score="34.3"
                     /tool="antismash"
                     /translation="ELKMIDPTCGSGHFVLGAFRRLVRLWAEGQPGRDVHERVRAALHS
                     IHGVDINPFAVAIARFRLLVAAIAASGVRTLAEAAKYEWPIHLAVGDSLIKARQLELTL
                     GGDEDGGYDPLASFTYATEDVHEHPGILQQGRYHVVVGNPPYITVK"
     misc_feature    complement(52517..52537)
                     /gene_synonym="SC6G9.02"
                     /locus_tag="SCO5331"
                     /note="PS00092 N-6 Adenine-specific DNA methylases
                     signature"
     gene            53879..55390
                     /db_xref="GeneID:1100772"
                     /gene_synonym="SC6G9.01c; SCBAC5H2.01"
                     /locus_tag="SCO5332"
     CDS             53879..55390
                     /codon_start=1
                     /db_xref="GeneID:1100772"
                     /gene_synonym="SC6G9.01c; SCBAC5H2.01"
                     /locus_tag="SCO5332"
                     /note="SCBAC5H2.01, unknown (fragment), len: >33 aa;
                     SC6G9.01c, hypothetical protein, partial CDS, len: >409 aa;
                     unknown function, possible CDS suggested by positional base
                     preference and amino acid composition. The coding sequence
                     has unusually low %G+C content. Alternative start codons
                     are present at codons 9 and 27"
                     /product="hypothetical protein"
                     /protein_id="NP_733661.1"
                     /transl_table=11
                     /translation="MFRNPGGFVRVSEYYGIGRSQGALDFVDVDITDDVPVYIDPGMIR
                     HLPDDWGKECLLMLTTFFDSVLDAVRKNDKKRARYLLGHLGEPNETHLGFSAGRSAGRG
                     FGKQMGVTLAEKLAASQAAQTGLIEDLEDTAFFIEKVGKDIVSDITTNIIRGPLIAYTQ
                     QMATVFGIPMEEGVASGAAWNPHSQDWEHGYVRLPIAGDRKLLLVPKVIVRRDLHMSRS
                     EYYRNHLVPALQSEELDKPSSRLVRTLKDGSRRVWVGDIKAHYGSTKPDVTRESLLRPD
                     IYANYREIKRKSAPPPISHGELSEISNTPLPDYEKLLTDVLQTPAGKDSAGEYHRRIEA
                     LLSAVFYPSLVMPELEEELHAGRKRVDISYTNVAQSGFFAFLGKHKIKSTYVMVECKNY
                     GKEVGNPELDQLSSRFSPLRGQFGILACRSFEDKDRFLKRCRDTALDYRGFVIALDDDD
                     LRELVADVLEAVNWIPADPPPAEPEVQPRVENYPLLFRRFKALVN"
     misc_feature    55007..56484
                     /note="low G+C region (58.79%)"
     gene            complement(55476..56381)
                     /db_xref="GeneID:1100773"
                     /gene_synonym="SCBAC5H2.02c"
                     /locus_tag="SCO5333"
     CDS             complement(55476..56381)
                     /codon_start=1
                     /db_xref="GeneID:1100773"
                     /gene_synonym="SCBAC5H2.02c"
                     /locus_tag="SCO5333"
                     /note="SCBAC5H2.02c, conserved hypothetical protein, len:
                     301 aa; similar to TR:Q9RU61 (EMBL:AE001997) Deinococcus
                     radiodurans conserved hypothetical protein DR1533, 299 aa;
                     fasta scores: opt: 496 z-score: 583.0 E(): 6.7e-25; 46.3%
                     identity in 298 aa overlap. Contains Pfam match to entry
                     PF02182 G9a, Domain of unknown function"
                     /product="hypothetical protein"
                     /protein_id="NP_629473.1"
                     /transl_table=11
                     /translation="MIGEIPGVAAGQPYNSRRLAHEAGVHRPLQAGICGTKATGAESIV
                     VSGGYKDDEDYGDVIIYTGHGGRDSAGNQVSDQSLDDSGNAALVTSYLRGLPVRVIRGS
                     QSGSPFAPSNGYRYDGLYRVASYTSKLGIDGFLIWQFRMEAYEETPTPKITKVRALFAE
                     PTDCAKQDPVAASGTEQPERVTSMVQRIVRSSAIADTVKAWHQDQCQTCGIHIEVPGGF
                     YSEGAHIQALGRPHNGPDRTDNMLCLCPNCHVMLDAGAIVLSDDLIVSKNGQLVGPLRT
                     HPKHKVNIECVRRHRERWRQ"
     PFAM_domain     complement(55593..55757)
                     /aSDomain="HNH_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13391.9"
                     /description="HNH endonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5333_0532"
                     /evalue="4.90E-06"
                     /label="SCO5333"
                     /locus_tag="SCO5333"
                     /protein_end="263"
                     /protein_start="208"
                     /score="26.7"
                     /tool="antismash"
                     /translation="CQTCGIHIEVPGGFYSEGAHIQALGRPHNGPDRTDNMLCLCPNCH
                     VMLDAGAIVL"
     misc_feature    complement(55935..56381)
                     /gene_synonym="SCBAC5H2.02c"
                     /locus_tag="SCO5333"
                     /note="Pfam match to entry PF02182 G9a, Domain of unknown
                     function, score 144.00, E-value 2.6e-39"
     PFAM_domain     complement(55950..56378)
                     /aSDomain="SAD_SRA"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02182.20"
                     /description="SAD/SRA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5333_0531"
                     /evalue="7.90E-48"
                     /label="SCO5333"
                     /locus_tag="SCO5333"
                     /protein_end="144"
                     /protein_start="1"
                     /score="162.2"
                     /tool="antismash"
                     /translation="IGEIPGVAAGQPYNSRRLAHEAGVHRPLQAGICGTKATGAESIVV
                     SGGYKDDEDYGDVIIYTGHGGRDSAGNQVSDQSLDDSGNAALVTSYLRGLPVRVIRGSQ
                     SGSPFAPSNGYRYDGLYRVASYTSKLGIDGFLIWQFRME"
     stem_loop       complement(56471..56622)
                     /note="possible stem loop. Score 125: 55/65 (84%) matches,
                     0 gaps"
     gene            complement(56900..57214)
                     /db_xref="GeneID:1100774"
                     /gene_synonym="SCBAC5H2.03c"
                     /locus_tag="SCO5334"
     CDS             complement(56900..57214)
                     /codon_start=1
                     /db_xref="GeneID:1100774"
                     /gene_synonym="SCBAC5H2.03c"
                     /locus_tag="SCO5334"
                     /note="SCBAC5H2.03c, unknown, len: 104 aa. Highly
                     hydrophilic. High content in arginine and serine amino acid
                     residues"
                     /product="hypothetical protein"
                     /protein_id="NP_629474.1"
                     /transl_table=11
                     /translation="MGDQAYQARRRSQRFKVPSTVEGMEPGVTQSGRVADVMQPRSSNE
                     KIPVSLGHSRGNLASPSSHGLSMQPAIPERRKQGLSEFRRSLGRVQCRRHGWNGSRVQR
                     "
     regulatory      complement(57217..57220)
                     /regulatory_class="ribosome_binding_site"
     gene            57227..57490
                     /db_xref="GeneID:1100775"
                     /gene_synonym="SCBAC5H2.04"
                     /locus_tag="SCO5335"
     CDS             57227..57490
                     /codon_start=1
                     /db_xref="GeneID:1100775"
                     /gene_synonym="SCBAC5H2.04"
                     /locus_tag="SCO5335"
                     /note="SCBAC5H2.04, unknown, len: 87 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_629475.1"
                     /transl_table=11
                     /translation="MYEAEQRGLSTELAVYEREDSPVLDALIFADMTTGPAGQSFDFDT
                     RIDEILVRYEPGSEVHNAISKARPYLQGAVERTRDRMAHQPM"
     gene            complement(57478..57948)
                     /db_xref="GeneID:1100776"
                     /gene_synonym="SCBAC5H2.05c"
                     /locus_tag="SCO5336"
     CDS             complement(57478..57948)
                     /codon_start=1
                     /db_xref="GeneID:1100776"
                     /gene_synonym="SCBAC5H2.05c"
                     /locus_tag="SCO5336"
                     /note="SCBAC5H2.05c, possible mutT-like protein, len: 156
                     aa; similar to plasmid borne SW:MUTT_STRAM (EMBL:Z19590)
                     Streptomyces ambofaciens plasmid pSAM2 mutT-like protein
                     ORF154, 154 aa; fasta scores: opt: 182 z-score: 232.1 E():
                     2.4e-05; 32.7% identity in 153 aa overlap. Contains Pfam
                     match to entry PF00293 mutT, MutT-like domain, and match to
                     Prosite entry PS00893 mutT domain signature"
                     /product="mutT-like protein"
                     /protein_id="NP_629476.1"
                     /transl_table=11
                     /translation="MARVDYFNDPNAPKANSLVPSVTAVARNEAGEVLLIHKTDNDLWA
                     LPGGGIDLGESAPDAAVRETKEETGFDVEVTGLVGIYTNPGHVMAYDDGEVRQQFSICY
                     HARITGGELRTSSESKEVAFVDPSKLDELNIHPSMRMRIEHGLTDRAEPYIG"
     misc_feature    complement(57502..57897)
                     /gene_synonym="SCBAC5H2.05c"
                     /locus_tag="SCO5336"
                     /note="Pfam match to entry PF00293 mutT, MutT-like domain,
                     score 97.10, E-value 3.5e-25"
     PFAM_domain     complement(57541..57894)
                     /aSDomain="NUDIX"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00293.31"
                     /description="NUDIX domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5336_0533"
                     /evalue="1.60E-17"
                     /label="SCO5336"
                     /locus_tag="SCO5336"
                     /protein_end="136"
                     /protein_start="18"
                     /score="63.9"
                     /tool="antismash"
                     /translation="VPSVTAVARNEAGEVLLIHKTDNDLWALPGGGIDLGESAPDAAVR
                     ETKEETGFDVEVTGLVGIYTNPGHVMAYDDGEVRQQFSICYHARITGGELRTSSESKEV
                     AFVDPSKLDELNIH"
     misc_feature    complement(57745..57804)
                     /gene_synonym="SCBAC5H2.05c"
                     /locus_tag="SCO5336"
                     /note="PS00893 mutT domain signature"
     gene            complement(57977..58708)
                     /db_xref="GeneID:1100777"
                     /gene_synonym="SCBAC5H2.06c"
                     /locus_tag="SCO5337"
     CDS             complement(57977..58708)
                     /codon_start=1
                     /db_xref="GeneID:1100777"
                     /gene_synonym="SCBAC5H2.06c"
                     /locus_tag="SCO5337"
                     /note="SCBAC5H2.06c, unknown, len: 243 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_629477.1"
                     /transl_table=11
                     /translation="MANERLRAAISAKGETIQSVAEHIGVDPKSVERWITTSRTPHRGH
                     RWKAASFLGVDEVYLWPSVEKQAEKASTSELITYYPHRGAVPAPLWSSLIEKATDQVDI
                     LVYAGLFLFDSHPDLPDQLAEKAKAGAQIRILLGDPDSEAVRQRGEEEGIGGDLAARAR
                     ITRRYLEPAMSTLGVEVRLHDTILYNSIYRFDEDVLVNPHVLGAPAGQNPVMHFRYLPG
                     ARTFRHYMRSFDYAWERGREA"
     regulatory      complement(58715..58719)
                     /regulatory_class="ribosome_binding_site"
     regulatory      58853..58857
                     /regulatory_class="ribosome_binding_site"
     gene            58866..59219
                     /db_xref="GeneID:1100778"
                     /gene_synonym="pra2; SCBAC5H2.07"
                     /locus_tag="SCO5338"
     CDS             58866..59219
                     /codon_start=1
                     /db_xref="GeneID:1100778"
                     /gene_synonym="pra2; SCBAC5H2.07"
                     /locus_tag="SCO5338"
                     /note="SCBAC5H2.07, pra2, probable regulatory protein, len:
                     117 aa; highly similar to plasmid borne TR:Q53733
                     (EMBL:Z34987) Streptomyces ambofaciens pSAM2 regulatory
                     protein Pra, 116 aa; fasta scores: opt: 535 z-score: 695.9
                     E(): 3.5e-31; 72.9% identity in 118 aa overlap and to
                     TR:Q9X8D1 (EMBL:AL049573) Streptomyces coelicolor Pra,
                     regulatory protein SCE39.08c, 118 aa; fasta scores: opt:
                     565 z-score: 733.8 E(): 0; 76.3% identity in 118 aa
                     overlap"
                     /product="regulatory protein"
                     /protein_id="NP_629478.1"
                     /transl_table=11
                     /translation="MRQIPVDTSNATVMVAKAPQPKVKDRRTGEIATDKDGVTLMVVEV
                     MFSTPDEVEILKLTVPQPGVSEDLTMGTPVALTGLVASAWENEFNGQKKHGIAFRAVAV
                     TSLAAGASSSKAA"
     misc_feature    59052..59087
                     /gene_synonym="pra2; SCBAC5H2.07"
                     /locus_tag="SCO5338"
                     /note="PS00178 Aminoacyl-transfer RNA synthetases class-I
                     signature"
     gene            59223..60578
                     /db_xref="GeneID:1100779"
                     /gene_synonym="SCBAC5H2.08; traSA2"
                     /locus_tag="SCO5339"
     CDS             59223..60578
                     /codon_start=1
                     /db_xref="GeneID:1100779"
                     /gene_synonym="SCBAC5H2.08; traSA2"
                     /locus_tag="SCO5339"
                     /note="SCBAC5H2.08, traSA2, probable plasmid transfer
                     protein, len: 451 aa; highly similar to TR:Q9X8D0
                     (EMBL:AL049573) Streptomyces coelicolor plasmid transfer
                     protein TraSA, 451 aa; fasta scores: opt: 2539 z-score:
                     2830.9 E(): 0; 84.3% identity in 451 aa overlap, to plasmid
                     borne SW:TRSA_STRAM (EMBL:Z19593) Streptomyces ambofaciens
                     transfer protein TraSA, 415 aa; fasta scores: opt: 2345
                     z-score: 2615.4 E(): 0; 84.8% identity in 415 aa overlap
                     and to TR:O86766 (EMBL:AL031035) Streptomyces coelicolor
                     traSA:integrase fusion protein SC6A9.34, 768 aa; fasta
                     scores: opt: 2326 z-score: 2253.5 E(): 0; 85.4% identity in
                     405 aa overlap. Contains Pfam match to entry PF01580
                     FtsK_SpoIIIE, FtsK/SpoIIIE family and match to Prosite
                     entry PS00017 ATP/GTP-binding site motif A (P-loop)"
                     /product="plasmid transfer protein"
                     /protein_id="NP_629479.1"
                     /transl_table=11
                     /translation="MTWLIVALVLVVAAAGLLRWRRPAWYWLTFGVTLAALRVLVRYGS
                     VMDACGLTVPAPRWRLTLARMTNRPVPGPRAPRILRFRVTRTGLVLRLKLRPGQDAFDV
                     AASCDRLRHSFAMYGVTSRELRSGVVELRMTGYDVLKRVQMPALAETRPMRVPVALRED
                     GAVHYRDYRAVPHGLVIGATESGKSVYQRNLVAALAPQRVALVGIDCKQGVELFPLARR
                     FSALADNPDTAAELLDALVSHMQDVYQLIRAEQRITADVPDAEIAADIWDLPENLRPVP
                     IVVLVDEVAELALFATKDDEKRRDRIITALARLAQLGRAAGIYLEICGQRFGSELGKGI
                     TMLRAQLTGRTAHRVNDEASANMAFGDIAPDAVLAAISIPTDTPGVAITGDSAGGWARI
                     RAPHTTLRQAVNVCNRHADLTPDLPALAPFRPALGTLAPVPAPAVESAPAAA"
     misc_feature    59637..60224
                     /gene_synonym="SCBAC5H2.08; traSA2"
                     /locus_tag="SCO5339"
                     /note="Pfam match to entry PF01580 FtsK_SpoIIIE,
                     FtsK/SpoIIIE family, score 210.00, E-value 3.7e-59"
     PFAM_domain     59640..60221
                     /aSDomain="FtsK_SpoIIIE"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01580.21"
                     /db_xref="GO:0000166"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0005524"
                     /description="FtsK/SpoIIIE family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5339_0534"
                     /evalue="7.90E-39"
                     /gene_ontologies="GO:0000166: nucleotide binding"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /label="SCO5339"
                     /locus_tag="SCO5339"
                     /protein_end="333"
                     /protein_start="139"
                     /score="133.6"
                     /tool="antismash"
                     /translation="LKRVQMPALAETRPMRVPVALREDGAVHYRDYRAVPHGLVIGATE
                     SGKSVYQRNLVAALAPQRVALVGIDCKQGVELFPLARRFSALADNPDTAAELLDALVSH
                     MQDVYQLIRAEQRITADVPDAEIAADIWDLPENLRPVPIVVLVDEVAELALFATKDDEK
                     RRDRIITALARLAQLGRAAGIYLEICGQRFG"
     misc_feature    59763..59786
                     /gene_synonym="SCBAC5H2.08; traSA2"
                     /locus_tag="SCO5339"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     regulatory      60588..60593
                     /regulatory_class="ribosome_binding_site"
     gene            60599..60796
                     /db_xref="GeneID:1100780"
                     /gene_synonym="SCBAC5H2.09"
                     /locus_tag="SCO5340"
     CDS             60599..60796
                     /codon_start=1
                     /db_xref="GeneID:1100780"
                     /gene_synonym="SCBAC5H2.09"
                     /locus_tag="SCO5340"
                     /note="SCBAC5H2.09, unknown, len: 65 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_629480.1"
                     /transl_table=11
                     /translation="MATAKKPTTRRKITPPAPEPALCPDCDGKGETRETVRVGARKMRV
                     TDDHQTALCLTCWGTGHATD"
     regulatory      60802..60811
                     /regulatory_class="ribosome_binding_site"
     gene            60818..61486
                     /db_xref="GeneID:1100781"
                     /gene_synonym="SCBAC5H2.10; spdA2"
                     /locus_tag="SCO5341"
     CDS             60818..61486
                     /codon_start=1
                     /db_xref="GeneID:1100781"
                     /gene_synonym="SCBAC5H2.10; spdA2"
                     /locus_tag="SCO5341"
                     /note="SCBAC5H2.10, spdA2 protein, len: 222 aa; highly
                     similar to plasmid borne TR:Q07193 (EMBL:Z19593)
                     Streptomyces ambofaciens probably involved in pSAM2
                     spreading (intramycelial transfer) SpdA protein, 224 aa;
                     fasta scores: opt: 1086 z-score: 974.5 E(): 0; 74.9%
                     identity in 223 aa overlap and to TR:Q9X8C9 (EMBL:AL049573)
                     Streptomyces coelicolor SpdA protein, 217 aa; fasta scores:
                     opt: 1079 z-score: 968.6 E(): 0; 75.5% identity in 220 aa
                     overlap. Contains possible hydrophobic membrane spanning
                     regions"
                     /product="SpdA2 protein"
                     /protein_id="NP_629481.1"
                     /transl_table=11
                     /translation="MRTVLRPDAVLVQAVIAGALSFAHLHDLAAAAGQDGWKAWAYPIS
                     VDLLFVAAWRRLRTDGPSRLSWCWFLIALAASLGANIATAGLLDLSDVPAWLRILVAGW
                     PALAFLGGTLLAHSPTGHAPDPDPAPEVEREPEPVPESDPEPAAVPAPQETPALPVAEP
                     APVPASPPAVPVPAALVDHARKVAADHEHRTGSRIDTDTLRARLGVPPHLADAIAAQLT
                     "
     PFAM_domain     60839..61171
                     /aSDomain="DUF2637"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF10935.11"
                     /description="Protein of unknown function (DUF2637)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5341_0535"
                     /evalue="1.60E-21"
                     /label="SCO5341"
                     /locus_tag="SCO5341"
                     /protein_end="118"
                     /protein_start="7"
                     /score="76.9"
                     /tool="antismash"
                     /translation="DAVLVQAVIAGALSFAHLHDLAAAAGQDGWKAWAYPISVDLLFVA
                     AWRRLRTDGPSRLSWCWFLIALAASLGANIATAGLLDLSDVPAWLRILVAGWPALAFLG
                     GTLLAHS"
     regulatory      61490..61497
                     /regulatory_class="ribosome_binding_site"
     gene            61508..61699
                     /db_xref="GeneID:1100782"
                     /gene_synonym="SCBAC5H2.11; spdB2"
                     /locus_tag="SCO5342"
     CDS             61508..61699
                     /codon_start=1
                     /db_xref="GeneID:1100782"
                     /gene_synonym="SCBAC5H2.11; spdB2"
                     /locus_tag="SCO5342"
                     /note="SCBAC5H2.11, spdB2 protein, len: 63 aa; highly
                     similar to plasmid borne TR:Q07194 (EMBL:Z19593)
                     Streptomyces ambofaciens probably involved in pSAM2
                     spreading (intramycelial transfer) SpdB protein, 58 aa;
                     fasta scores: opt: 354 z-score: 518.8 E(): 2.5e-21; 82.3%
                     identity in 62 aa overlap and to TR:Q9X8C8 (EMBL:AL049573)
                     Streptomyces coelicolor SpdB protein, 53 aa; fasta scores:
                     opt: 350 z-score: 513.7 E(): 4.9e-21; 90.4% identity in 52
                     aa overlap"
                     /product="SpdB2 protein"
                     /protein_id="NP_629482.1"
                     /transl_table=11
                     /translation="MPARDFFHSVMRIGPVQIGTHRDRHGQTKHAAVCSNDGCGWSADY
                     TSQSAAQLAARTHRCKIR"
     PFAM_domain     61541..61690
                     /aSDomain="SpdB"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05122.16"
                     /description="Mobile element transfer protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5342_0536"
                     /evalue="5.30E-33"
                     /label="SCO5342"
                     /locus_tag="SCO5342"
                     /protein_end="61"
                     /protein_start="11"
                     /score="113.2"
                     /tool="antismash"
                     /translation="RIGPVQIGTHRDRHGQTKHAAVCSNDGCGWSADYTSQSAAQLAAR
                     THRCK"
     regulatory      61698..61703
                     /regulatory_class="ribosome_binding_site"
     gene            61710..61865
                     /db_xref="GeneID:1100783"
                     /gene_synonym="SCBAC5H2.12; spdC2"
                     /locus_tag="SCO5343"
     CDS             61710..61865
                     /codon_start=1
                     /db_xref="GeneID:1100783"
                     /gene_synonym="SCBAC5H2.12; spdC2"
                     /locus_tag="SCO5343"
                     /note="SCBAC5H2.12, spdC2 protein, len: 51 aa; identical to
                     plasmid borne TR:Q07195 (EMBL:AJ005260) Streptomyces
                     ambofaciens probably involved in pSAM2 spreading
                     (intramycelial transfer) SpdC, 51 aa and highly similar to
                     TR:Q9X8C7 (EMBL:AL049573) Streptomyces coelicolor SpdC
                     protein, 51 aa; fasta scores: opt: 280 z-score: 413.2 E():
                     1.9e-15; 78.4% identity in 51 aa overlap. Contains possible
                     hydrophobic membrane spanning region"
                     /product="SpdC2 protein"
                     /protein_id="NP_629483.1"
                     /transl_table=11
                     /translation="MDVPLWFALLCVGVLGVKLIRPPWWLIAVLLLGGYLLADSLLAPV
                     IDTAVK"
     regulatory      61864..61869
                     /regulatory_class="ribosome_binding_site"
     gene            61878..62201
                     /db_xref="GeneID:1100784"
                     /gene_synonym="SCBAC5H2.13; spdD2"
                     /locus_tag="SCO5344"
     CDS             61878..62201
                     /codon_start=1
                     /db_xref="GeneID:1100784"
                     /gene_synonym="SCBAC5H2.13; spdD2"
                     /locus_tag="SCO5344"
                     /note="SCBAC5H2.13, spdD2 protein, len: 107 aa; highly
                     similar to plasmid borne TR:Q07196 (EMBL:AJ005260)
                     Streptomyces ambofaciens probably involved in pSAM2
                     spreading (intramycelial transfer) SpdD protein, 104 aa;
                     fasta scores: opt: 517 z-score: 454.5 E(): 9.7e-18; 74.5%
                     identity in 106 aa overlap and to TR:Q9X8C6 (EMBL:AL049573)
                     Streptomyces coelicolor SpdD protein, 105 aa; fasta scores:
                     opt: 485 z-score: 428.0 E(): 2.9e-16; 70.6% identity in 109
                     aa overlap. Contains possible hydrophobic membrane spanning
                     regions"
                     /product="SpdD2 protein"
                     /protein_id="NP_629484.1"
                     /transl_table=11
                     /translation="MLRPKLPTMPQPTSTVTPPAVIEPTTITPGTPPPTPTAPAPAPVS
                     ARPTMQLTPGTALALVGGGTAVVLVVGAVLVSMLLAVAITAASVAVCAVVLRSLLASDA
                     KRR"
     gene            62291..62842
                     /db_xref="GeneID:1100785"
                     /gene_synonym="SCBAC5H2.14"
                     /locus_tag="SCO5345"
     CDS             62291..62842
                     /codon_start=1
                     /db_xref="GeneID:1100785"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 126.9; E-value:
                     2.4e-38)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCBAC5H2.14"
                     /locus_tag="SCO5345"
                     /note="SCBAC5H2.14, conserved hypothetical protein, len:
                     183 aa; highly similar to plasmid borne TR:CAA06454
                     (EMBL:AJ005260) Streptomyces ambofaciens unknown ORF183,
                     183 aa; fasta scores: opt: 1018 z-score: 1225.2 E(): 0;
                     81.4% identity in 183 aa overlap. Contains Pfam match to
                     entry PF00990 DUF9, Domain of unknown function DUF9 and a
                     TTA leucine codon, possible target for bldA regulation"
                     /product="hypothetical protein"
                     /protein_id="NP_629485.1"
                     /transl_table=11
                     /translation="MDLQIAAALVPLLGWAVHGSILTHRLVSARRDPLTGLHTRAGWTA
                     RAEHCIRRHPDAAVLLLDLDHFKTLNDTHGHAAGDAALVATADRLRTWCGRHGTAGRLG
                     GDEFVAVVQDLTAADLDALIAALHRPLHYAGRSLPLAASVGVCRLAELPMPLLTDALAA
                     ADAAMYAAKGRSRRGSRLSR"
     misc_feature    62324..62326
                     /gene_synonym="SCBAC5H2.14"
                     /locus_tag="SCO5345"
                     /note="TTA leucine codon. Possible target for bldA
                     regulation"
     misc_feature    62324..62326
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    62354..62824
                     /gene_synonym="SCBAC5H2.14"
                     /locus_tag="SCO5345"
                     /note="Pfam match to entry PF00990 DUF9, Domain of unknown
                     function DUF9, score 168.10, E-value 1.5e-46"
     aSDomain        62372..62827
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5345_0066"
                     /evalue="9.70E-28"
                     /identifier="TIGR00254"
                     /label="SCO5345"
                     /locus_tag="SCO5345"
                     /protein_end="179"
                     /protein_start="27"
                     /score="94.9"
                     /tool="antismash"
                     /translation="SARRDPLTGLHTRAGWTARAEHCIRRHPDAAVLLLDLDHFKTLND
                     THGHAAGDAALVATADRLRTWCGRHGTAGRLGGDEFVAVVQDLTAADLDALIAALHRPL
                     HYAGRSLPLAASVGVCRLAELPMPLLTDALAAADAAMYAAKGRSRRGS"
     PFAM_domain     62378..62818
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00990.24"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5345_0537"
                     /evalue="2.40E-30"
                     /label="SCO5345"
                     /locus_tag="SCO5345"
                     /protein_end="176"
                     /protein_start="29"
                     /score="105.5"
                     /tool="antismash"
                     /translation="RRDPLTGLHTRAGWTARAEHCIRRHPDAAVLLLDLDHFKTLNDTH
                     GHAAGDAALVATADRLRTWCGRHGTAGRLGGDEFVAVVQDLTAADLDALIAALHRPLHY
                     AGRSLPLAASVGVCRLAELPMPLLTDALAAADAAMYAAKGRSR"
     regulatory      62912..62918
                     /regulatory_class="ribosome_binding_site"
     gene            62928..63113
                     /db_xref="GeneID:1100786"
                     /gene_synonym="SCBAC5H2.15"
                     /locus_tag="SCO5346"
     CDS             62928..63113
                     /codon_start=1
                     /db_xref="GeneID:1100786"
                     /gene_synonym="SCBAC5H2.15"
                     /locus_tag="SCO5346"
                     /note="SCBAC5H2.15, unknown, len: 61 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_629486.1"
                     /transl_table=11
                     /translation="MAQHTPPAPRICPACDGFATVAVTLGGRDPRGHLRTLTTDCPACH
                     GTGTAPAHRVREGARA"
     regulatory      63095..63099
                     /gene_synonym="SCBAC5H2.15"
                     /locus_tag="SCO5346"
                     /regulatory_class="ribosome_binding_site"
     gene            63106..64470
                     /db_xref="GeneID:1100787"
                     /gene_synonym="repSA2; SCBAC5H2.16"
                     /locus_tag="SCO5347"
     CDS             63106..64470
                     /codon_start=1
                     /db_xref="GeneID:1100787"
                     /gene_synonym="repSA2; SCBAC5H2.16"
                     /locus_tag="SCO5347"
                     /note="SCBAC5H2.16, repSA2, replication initiation protein,
                     len: 454 aa; highly similar to plasmid borne SW:REPS_STRAM
                     (EMBL:Z19594) Streptomyces ambofaciens replication
                     initiation protein repSA, 459 aa; fasta scores: opt: 2806
                     z-score: 3256.0 E(): 0; 90.8% identity in 446 aa overlap
                     and to TR:Q9X8C5 (EMBL:AL049573) Streptomyces coelicolor
                     replication initiation protein repSA, 466 aa; fasta scores:
                     opt: 2759 z-score: 3201.4 E(): 0; 88.1% identity in 453 aa
                     overlap"
                     /product="replication initiation protein"
                     /protein_id="NP_629487.1"
                     /transl_table=11
                     /translation="MPDTLLDPTTLGDLLRVASAPDYTRWEDQIRRTGGCADPIHLTGW
                     TLHKDKTTGATLHHYTTADEPGGRLRLACGNRRASRCPACAWTYAGDTYHLIRAGLAGD
                     DRRDIPATVRDHPRVFATLTAPSFGPVHNRPDRGTCRCGTHHAPDAPELGTALDPDTYD
                     YAGAVLFNNHAGQLWQRFTNRLRREVAARAGLTQRELKECARLSYGKVAEFQKRGAVHF
                     HAVIRLDGPDGPDTPPPVWATVDLLTDAIRAAAGHSYTSVSVPAADGQPARTFRWGTQL
                     DVRPVKAFGDGSDITEQAVASYVAKYATKAAENTGTLDRRIGELAELDRHGVPDHTRRL
                     IEACKTLDSLYPDRRLWAWAHMLGFRGHFSSKSRRYSTTLGALRQARADYRAAQGHAAL
                     GIDDAEPDTVLVLADWQYAGHGHTPGESVLAATIARDLQLNRQTAREELAALEGA"
     PFAM_domain     63169..64407
                     /aSDomain="RepSA"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF20199.1"
                     /description="Replication initiator protein, pSAM2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5347_0538"
                     /evalue="4.80E-147"
                     /label="SCO5347"
                     /locus_tag="SCO5347"
                     /protein_end="434"
                     /protein_start="21"
                     /score="490.7"
                     /tool="antismash"
                     /translation="DYTRWEDQIRRTGGCADPIHLTGWTLHKDKTTGATLHHYTTADEP
                     GGRLRLACGNRRASRCPACAWTYAGDTYHLIRAGLAGDDRRDIPATVRDHPRVFATLTA
                     PSFGPVHNRPDRGTCRCGTHHAPDAPELGTALDPDTYDYAGAVLFNNHAGQLWQRFTNR
                     LRREVAARAGLTQRELKECARLSYGKVAEFQKRGAVHFHAVIRLDGPDGPDTPPPVWAT
                     VDLLTDAIRAAAGHSYTSVSVPAADGQPARTFRWGTQLDVRPVKAFGDGSDITEQAVAS
                     YVAKYATKAAENTGTLDRRIGELAELDRHGVPDHTRRLIEACKTLDSLYPDRRLWAWAH
                     MLGFRGHFSSKSRRYSTTLGALRQARADYRAAQGHAALGIDDAEPDTVLVLADWQYAGH
                     GHTPGESVLAATIA"
     regulatory      64460..64465
                     /gene_synonym="repSA2; SCBAC5H2.16"
                     /locus_tag="SCO5347"
                     /regulatory_class="ribosome_binding_site"
     gene            64472..64657
                     /db_xref="GeneID:1100788"
                     /gene_synonym="SCBAC5H2.17"
                     /locus_tag="SCO5348"
     CDS             64472..64657
                     /codon_start=1
                     /db_xref="GeneID:1100788"
                     /gene_synonym="SCBAC5H2.17"
                     /locus_tag="SCO5348"
                     /note="SCBAC5H2.17, possible excisionase, len: 61 aa;
                     similar to TR:Q53965 (EMBL:X71358) Streptomyces coelicolor
                     plasmid SLP1 DNA for xis and int genes, Xis, 61 aa; fasta
                     scores: opt: 148 z-score: 233.1 E(): 2.1e-05; 38.3%
                     identity in 60 aa overlap"
                     /product="excisionase"
                     /protein_id="NP_629488.1"
                     /transl_table=11
                     /translation="MKDELMTVPQILDELGGVSRRTFYRWRELGQGPAAFKLPNGELRV
                     WRSDFRTWLRQLEAAA"
     PFAM_domain     64484..64639
                     /aSDomain="HTH_17"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF12728.10"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5348_0539"
                     /evalue="1.20E-07"
                     /label="SCO5348"
                     /locus_tag="SCO5348"
                     /protein_end="56"
                     /protein_start="4"
                     /score="32.0"
                     /tool="antismash"
                     /translation="LMTVPQILDELGGVSRRTFYRWRELGQGPAAFKLPNGELRVWRSD
                     FRTWLRQ"
     regulatory      64642..64646
                     /gene_synonym="SCBAC5H2.17"
                     /locus_tag="SCO5348"
                     /regulatory_class="ribosome_binding_site"
     gene            64654..66027
                     /db_xref="GeneID:1100789"
                     /gene_synonym="SCBAC5H2.18"
                     /locus_tag="SCO5349"
     CDS             64654..66027
                     /codon_start=1
                     /db_xref="GeneID:1100789"
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 99.3; E-value: 5.7e-30)"
                     /gene_kind="other"
                     /gene_synonym="SCBAC5H2.18"
                     /locus_tag="SCO5349"
                     /note="SCBAC5H2.18, probable integrase, len: 457 aa;
                     similar to TR:CAC08268 (EMBL:AL392146) Streptomyces
                     coelicolor integrase Int, 455 aa; fasta scores: opt: 1486
                     z-score: 1774.0 E(): 0; 50.3% identity in 455 aa overlap
                     and to plasmid borne TR:Q53966 (EMBL:X71358) Streptomyces
                     coelicolor plasmid SLP1 DNA for xis and int genes, Int, 455
                     aa; fasta scores: opt: 1486 z-score: 1774.0 E(): 0; 50.3%
                     identity in 455 aa overlap"
                     /product="integrase"
                     /protein_id="NP_629489.1"
                     /transl_table=11
                     /translation="MKSLDVKVWGVRKRNTKKSSYDVRWTVAGNVFSEQFRTKGLADHY
                     RSKLLRAAHGGEEFDTVTGLPDSMVEKAASMSWYAFALRYLAMKWPHAAPNTRNGINES
                     LTAVTMTLLDDRPGRPPEELIRRALRNWAFVLPGPDDRELPDEIAHALHWVSKASRPLA
                     DLGDAAIARAVLDALKLKLDGTAAAAETVRRKRRTLVNALHYAVDLGEFKENPITGIRW
                     KKPKVAGEVDPRVVANPEQARSLLTAVSYVGGYGRARGRRLVGLFACMYYGAFRPAEAV
                     GLTAADLKLPETGWGTALLNRTRPSAGKQWTDSGETHDDRGLKNRPAEEVRLVPIPPQL
                     VAILRRHLDTFGTAEDGRLFTNERGGVVGSSTYYRVWQEARAFALLPAAVASPLAARPY
                     DLRHSALSTWLNAGVDPTEVAARAGNSVEVLLSRYAKCIDGRQEVVNRKIEELLREYE"
     PFAM_domain     65368..65928
                     /aSDomain="Phage_integrase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00589.25"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0006310"
                     /db_xref="GO:0015074"
                     /description="Phage integrase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5349_0540"
                     /evalue="2.90E-07"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0006310: DNA recombination"
                     /gene_ontologies="GO:0015074: DNA integration"
                     /label="SCO5349"
                     /locus_tag="SCO5349"
                     /protein_end="425"
                     /protein_start="238"
                     /score="30.6"
                     /tool="antismash"
                     /translation="PEQARSLLTAVSYVGGYGRARGRRLVGLFACMYYGAFRPAEAVGL
                     TAADLKLPETGWGTALLNRTRPSAGKQWTDSGETHDDRGLKNRPAEEVRLVPIPPQLVA
                     ILRRHLDTFGTAEDGRLFTNERGGVVGSSTYYRVWQEARAFALLPAAVASPLAARPYDL
                     RHSALSTWLNAGVDPTEVAARAGN"
     gene            66059..66604
                     /db_xref="GeneID:1100790"
                     /gene_synonym="SCBAC5H2.19"
                     /locus_tag="SCO5350"
     CDS             66059..66604
                     /codon_start=1
                     /db_xref="GeneID:1100790"
                     /gene_synonym="SCBAC5H2.19"
                     /locus_tag="SCO5350"
                     /note="SCBAC5H2.19, unknown, len: 181 aa. Contains two TTA
                     leucine codons, possible targets for bldA regulation"
                     /product="hypothetical protein"
                     /protein_id="NP_629490.1"
                     /transl_table=11
                     /translation="MDWGLRYISAACRRSLVVGCTCRVAFGLAGGLLPQRFRPVRALRL
                     GCRTGDPHGMGLLEREPRRLSGGQSRCPDCGLLQDRVPTLEQDWVLLEPDMNPLAHTVP
                     AEHRWIELSDGRVTVYEVCPPDQSQRCRVEHRLACPARPLPDLWPWLTSLRGENARRVE
                     RQNDPEPPPPPEEWPDAG"
     PFAM_domain     66224..66559
                     /aSDomain="DUF6083"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19561.2"
                     /description="Family of unknown function (DUF6083)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5350_0541"
                     /evalue="7.10E-31"
                     /label="SCO5350"
                     /locus_tag="SCO5350"
                     /protein_end="167"
                     /protein_start="55"
                     /score="106.4"
                     /tool="antismash"
                     /translation="GLLEREPRRLSGGQSRCPDCGLLQDRVPTLEQDWVLLEPDMNPLA
                     HTVPAEHRWIELSDGRVTVYEVCPPDQSQRCRVEHRLACPARPLPDLWPWLTSLRGENA
                     RRVERQND"
     misc_feature    66230..66232
                     /gene_synonym="SCBAC5H2.19"
                     /locus_tag="SCO5350"
                     /note="TTA leucine codon, possible target for bldA
                     regulation"
     misc_feature    66230..66232
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    66290..66292
                     /gene_synonym="SCBAC5H2.19"
                     /locus_tag="SCO5350"
                     /note="TTA leucine codon, possible target for bldA
                     regulation"
     misc_feature    66290..66292
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(66777..66851)
                     /db_xref="GeneID:3240058"
                     /locus_tag="SCOt55"
     tRNA            complement(66777..66851)
                     /db_xref="GeneID:3240058"
                     /locus_tag="SCOt55"
                     /note="tRNA Arg anticodon CCG, Cove score 77.44"
                     /product="tRNA-Arg"
     gene            67031..67534
                     /db_xref="GeneID:1100791"
                     /gene_synonym="SCBAC5H2.20"
                     /locus_tag="SCO5351"
     CDS             67031..67534
                     /codon_start=1
                     /db_xref="GeneID:1100791"
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 100.9; E-value: 1.3e-30)"
                     /gene_kind="regulatory"
                     /gene_synonym="SCBAC5H2.20"
                     /locus_tag="SCO5351"
                     /note="SCBAC5H2.20, possible regulatory protein, len: 167
                     aa; similar to the N-terminal domain of several regulatory
                     proteins, e.g. TR:Q9X6C1 (EMBL:AF135389) Tolypothrix
                     PCC7601 DNA binding response regulator RpaA, 247 aa; fasta
                     scores: opt: 332 z-score: 343.7 E(): 1.4e-11; 42.0%
                     identity in 119 aa overlap. Contains Pfam match to entry
                     PF00072 response_reg, Response regulator receiver domain"
                     /product="regulatory protein"
                     /protein_id="NP_629491.1"
                     /transl_table=11
                     /translation="MPRPSGRILVVDDNKVIRQLIRVNLELEGFEVVTAGDGAECLEVV
                     QQVRPDAVTLDVVMPRLDGLRTAARLRADPRTRDLPIAIVSACTQYEVDAGSAAGADAF
                     LSKPFEPAELVGLVRQLVERKGSGSTVVRGASGAGPGQPGPGAGASPPRVRGLAGESGA
                     SAQA"
     misc_feature    67046..67384
                     /gene_synonym="SCBAC5H2.20"
                     /locus_tag="SCO5351"
                     /note="Pfam match to entry PF00072 response_reg, Response
                     regulator receiver domain, score 115.90, E-value 7.5e-31"
     PFAM_domain     67052..67384
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00072.27"
                     /db_xref="GO:0000160"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5351_0542"
                     /evalue="5.60E-25"
                     /gene_ontologies="GO:0000160: phosphorelay signal
                     transduction system"
                     /label="SCO5351"
                     /locus_tag="SCO5351"
                     /protein_end="118"
                     /protein_start="7"
                     /score="87.8"
                     /tool="antismash"
                     /translation="ILVVDDNKVIRQLIRVNLELEGFEVVTAGDGAECLEVVQQVRPDA
                     VTLDVVMPRLDGLRTAARLRADPRTRDLPIAIVSACTQYEVDAGSAAGADAFLSKPFEP
                     AELVGLV"
     gene            67656..68699
                     /db_xref="GeneID:1100792"
                     /gene_synonym="SCBAC5H2.21"
                     /locus_tag="SCO5352"
     CDS             67656..68699
                     /codon_start=1
                     /db_xref="GeneID:1100792"
                     /gene_synonym="SCBAC5H2.21"
                     /locus_tag="SCO5352"
                     /note="SCBAC5H2.21, possible arginyl tRNA synthetase, len:
                     347 aa; similar to SW:SYR_BRELA (EMBL:Z21501)
                     Brevibacterium lactofermentum arginyl tRNA synthetase (EC
                     6.1.1.19) ArgS, 550 aa; fasta scores (to C-terminal
                     region): opt: 234 z-score: 260.2 E(): 6.4e-07; 36.0%
                     identity in 161 aa overlap and blastp scores (to N-terminal
                     region): Score = 182 (64.1 bits), Expect = 1.2e-28, Sum
                     P(2) = 1.2e-28; Identities = 45/116 (38%), Positives =
                     65/116 (56%) and similar to SW:SYR_MYCTU (EMBL:Z73419)
                     Mycobacterium tuberculosis arginyl t-RNA synthetase (EC
                     6.1.1.19) ArgS or MTCY373.12, 550 aa; fasta scores: opt:
                     216 z-score: 240.5 E(): 8.1e-06; 28.1% identity in 363 aa
                     overlap"
                     /product="arginyl tRNA synthetase"
                     /protein_id="NP_629492.1"
                     /transl_table=11
                     /translation="MTPVELSRTVLHAVRRAVDAGELSVAVPTRAVVAPPGPGGCGDYA
                     TGIALQLARPAGQPPFRVAEVLRPYLVGTDGITDVVLTGPGFLNISLDRAASDVGLVAE
                     ILRRGDRYGHADQPDGRVVQLHCPHDLRAVVVAEASARLLRSQGALVRVSAEGFEDAWT
                     SVLGVTVDAVGHAPAELPVNVRPVPAHGSADPMSLGRDAGRWALLHPAAGDRPRIGDEH
                     LVQREGNPLFRVRYAHARARAAARNAAGLGFTAAPGPVAERDLLAALADHPRVLAAAAD
                     HRAPDRLARHLVTVADAALPFLPTVLPRGGEKPSAAHRARLALAEAVGAVLAGGLALLG
                     IDAPEHL"
     PFAM_domain     67689..67931
                     /aSDomain="Arg_tRNA_synt_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03485.19"
                     /db_xref="GO:0000166"
                     /db_xref="GO:0004814"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0005737"
                     /db_xref="GO:0006420"
                     /description="Arginyl tRNA synthetase N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5352_0543"
                     /evalue="4.30E-11"
                     /gene_ontologies="GO:0000166: nucleotide binding"
                     /gene_ontologies="GO:0004814: arginine-tRNA ligase
                     activity"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0005737: cytoplasm"
                     /gene_ontologies="GO:0006420: arginyl-tRNA aminoacylation"
                     /label="SCO5352"
                     /locus_tag="SCO5352"
                     /protein_end="92"
                     /protein_start="11"
                     /score="43.4"
                     /tool="antismash"
                     /translation="HAVRRAVDAGELSVAVPTRAVVAPPGPGGCGDYATGIALQLARPA
                     GQPPFRVAEVLRPYLVGTDGITDVVLTGPGFLNISL"
     PFAM_domain     68355..68696
                     /aSDomain="DALR_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05746.18"
                     /db_xref="GO:0004814"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0006420"
                     /description="DALR anticodon binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5352_0544"
                     /evalue="1.00E-18"
                     /gene_ontologies="GO:0004814: arginine-tRNA ligase
                     activity"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0006420: arginyl-tRNA aminoacylation"
                     /label="SCO5352"
                     /locus_tag="SCO5352"
                     /protein_end="347"
                     /protein_start="233"
                     /score="67.7"
                     /tool="antismash"
                     /translation="VRYAHARARAAARNAAGLGFTAAPGPVAERDLLAALADHPRVLAA
                     AADHRAPDRLARHLVTVADAALPFLPTVLPRGGEKPSAAHRARLALAEAVGAVLAGGLA
                     LLGIDAPEHL"
     gene            68718..70109
                     /db_xref="GeneID:1100793"
                     /gene_synonym="lysA; SCBAC5H2.22"
                     /locus_tag="SCO5353"
     CDS             68718..70109
                     /codon_start=1
                     /db_xref="GeneID:1100793"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 430.3;
                     E-value: 8.8e-131)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="lysA; SCBAC5H2.22"
                     /locus_tag="SCO5353"
                     /note="SCBAC5H2.22, lysA, diaminopimelate decarboxylase,
                     len: 463 aa; highly similar to SW:DCDA_CORGL (EMBL:X07563)
                     Corynebacterium glutamicum diaminopimelate decarboxylase
                     (EC 4.1.1.20) LysA, 445 aa; fasta scores: opt: 1503
                     z-score: 1722.5 E(): 0; 51.0% identity in 443 aa overlap.
                     Contains Pfam match to entry PF00278 Orn_DAP_Arg_deC,
                     Pyridoxal-dependent decarboxylase and matches to Prosite
                     entries PS00878 Orn/DAP/Arg decarboxylases family 2
                     pyridoxal-P attachment site and PS00879 Orn/DAP/Arg
                     decarboxylases family 2 signature 2"
                     /product="diaminopimelate decarboxylase"
                     /protein_id="NP_629493.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 6.7e-69, bitscore:
                     230.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 6.9e-14,
                     bitscore: 50.7, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRSAHPAGPRHADVLPEGHYTAPADDLNALDPKVWARTVGRDAD
                     GVVTVGGIPVTQLAEEYGTPAYLLDEADFRERARAWRTAFGDDADVFYAGKAFLSRAVV
                     RWLDEEGLNLDVCSGGELATALSAGMPAERIAFHGNNKSPEEIERAVRAGVGRIVLDSF
                     QEIVRVAHIAQSLGKRQRVQIRITVGVEAHTHEFIATAHEDQKFGIPLAGGQAAEAVRR
                     ALKLDGLEVIGIHSHIGSQIFDMSGFEVAAHRVVGLLKDIRDEHGVELPEIDLGGGLGI
                     AYTSDDDPREPHEIAKALTEIVTRECEAARLATPRISVEPGRAIVGPTAFTLYEVGTVK
                     PLEGLRTYVSVDGGMSDNIRTALYDAEYSVALASRTSDAEPMLVRVVGKHCESGDIVVK
                     DAFLPGDLAPGDLIAVPATGAYCRSMASNYNHALRPPVVAVRDGAARVVVRRETEEDLL
                     RLDVG"
     aSDomain        68844..70100
                     /aSDomain="TIGR01048"
                     /aSTool="tigrfam"
                     /description="lysA: diaminopimelate decarboxylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5353_0067"
                     /evalue="9.50E-147"
                     /identifier="TIGR01048"
                     /label="SCO5353"
                     /locus_tag="SCO5353"
                     /protein_end="461"
                     /protein_start="42"
                     /score="486.8"
                     /tool="antismash"
                     /translation="DADGVVTVGGIPVTQLAEEYGTPAYLLDEADFRERARAWRTAFGD
                     DADVFYAGKAFLSRAVVRWLDEEGLNLDVCSGGELATALSAGMPAERIAFHGNNKSPEE
                     IERAVRAGVGRIVLDSFQEIVRVAHIAQSLGKRQRVQIRITVGVEAHTHEFIATAHEDQ
                     KFGIPLAGGQAAEAVRRALKLDGLEVIGIHSHIGSQIFDMSGFEVAAHRVVGLLKDIRD
                     EHGVELPEIDLGGGLGIAYTSDDDPREPHEIAKALTEIVTRECEAARLATPRISVEPGR
                     AIVGPTAFTLYEVGTVKPLEGLRTYVSVDGGMSDNIRTALYDAEYSVALASRTSDAEPM
                     LVRVVGKHCESGDIVVKDAFLPGDLAPGDLIAVPATGAYCRSMASNYNHALRPPVVAVR
                     DGAARVVVRRETEEDLLRLD"
     misc_feature    68916..70013
                     /gene_synonym="lysA; SCBAC5H2.22"
                     /locus_tag="SCO5353"
                     /note="Pfam match to entry PF00278 Orn_DAP_Arg_deC,
                     Pyridoxal-dependent decarboxylase, score 400.80, E-value
                     5.1e-119"
     PFAM_domain     68931..69698
                     /aSDomain="Orn_Arg_deC_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02784.19"
                     /db_xref="GO:0003824"
                     /description="Pyridoxal-dependent decarboxylase, pyridoxal
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5353_0545"
                     /evalue="1.70E-68"
                     /gene_ontologies="GO:0003824: catalytic activity"
                     /label="SCO5353"
                     /locus_tag="SCO5353"
                     /protein_end="327"
                     /protein_start="71"
                     /score="230.8"
                     /tool="antismash"
                     /translation="ADFRERARAWRTAFGDDADVFYAGKAFLSRAVVRWLDEEGLNLDV
                     CSGGELATALSAGMPAERIAFHGNNKSPEEIERAVRAGVGRIVLDSFQEIVRVAHIAQS
                     LGKRQRVQIRITVGVEAHTHEFIATAHEDQKFGIPLAGGQAAEAVRRALKLDGLEVIGI
                     HSHIGSQIFDMSGFEVAAHRVVGLLKDIRDEHGVELPEIDLGGGLGIAYTSDDDPREPH
                     EIAKALTEIVTRECEAARLATPRISVEPGRAIVG"
     misc_feature    68994..69050
                     /gene_synonym="lysA; SCBAC5H2.22"
                     /locus_tag="SCO5353"
                     /note="PS00878 Orn/DAP/Arg decarboxylases family 2
                     pyridoxal-P attachment site"
     misc_feature    69516..69557
                     /gene_synonym="lysA; SCBAC5H2.22"
                     /locus_tag="SCO5353"
                     /note="PS00879 Orn/DAP/Arg decarboxylases family 2
                     signature 2"
     PFAM_domain     69714..69974
                     /aSDomain="Orn_DAP_Arg_deC"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00278.25"
                     /db_xref="GO:0003824"
                     /description="Pyridoxal-dependent decarboxylase, C-terminal
                     sheet domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5353_0546"
                     /evalue="9.10E-15"
                     /gene_ontologies="GO:0003824: catalytic activity"
                     /label="SCO5353"
                     /locus_tag="SCO5353"
                     /protein_end="419"
                     /protein_start="332"
                     /score="54.8"
                     /tool="antismash"
                     /translation="LYEVGTVKPLEGLRTYVSVDGGMSDNIRTALYDAEYSVALASRTS
                     DAEPMLVRVVGKHCESGDIVVKDAFLPGDLAPGDLIAVPATG"
     misc_feature    complement(70166..70180)
                     /note="TFBS match to ZuR, Zinc-responsive repressor,
                     confidence: weak, score: 18.47"
                     /tool="antismash"
     regulatory      70260..70264
                     /regulatory_class="ribosome_binding_site"
     gene            70271..71560
                     /db_xref="GeneID:1100794"
                     /gene_synonym="SCBAC5H2.23; thrA"
                     /locus_tag="SCO5354"
     CDS             70271..71560
                     /EC_number="1.1.1.3"
                     /codon_start=1
                     /db_xref="GeneID:1100794"
                     /gene_synonym="SCBAC5H2.23; thrA"
                     /locus_tag="SCO5354"
                     /note="catalyzes the formation of L-aspartate
                     4-semialdehyde from L-homoserine"
                     /product="homoserine dehydrogenase"
                     /protein_id="NP_629494.1"
                     /transl_table=11
                     /translation="MRTRPLKVALLGCGVVGSKVARIMTTHAADLAARIGAPVELAGVA
                     VRRPDKVREGIDPALVTTDATALVKRGDIDVVVEVIGGIEPARTLITTAFAHGASVVSA
                     NKALIAQDGAALHAAADEHGKDLYYEAAVAGAIPLIRPLRESLAGDKVNRVLGIVNGTT
                     NFILDAMDSTGAGYQEALDEATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLD
                     DVYREGMTEVTAADFASAKEMGCTIKLLAICERAADGGSVTARVHPAMIPLSHPLANVR
                     EAYNAVFVESDAAGQLMFYGPGAGGSPTASAVLGDLVAVCRNRLGGATGPGESAYAALP
                     VSPMGDVVTRYHISLDVADKPGVLAQVATVFAEHGVSIDTVRQSGKDGEASLVVVTHRA
                     SDAALGGTVEALRKLDTVRGVASIMRVEGE"
     PFAM_domain     70304..70660
                     /aSDomain="NAD_binding_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03447.19"
                     /db_xref="GO:0016491"
                     /db_xref="GO:0050661"
                     /description="Homoserine dehydrogenase, NAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5354_0547"
                     /evalue="3.20E-20"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /gene_ontologies="GO:0050661: NADP binding"
                     /label="SCO5354"
                     /locus_tag="SCO5354"
                     /protein_end="130"
                     /protein_start="11"
                     /score="73.0"
                     /tool="antismash"
                     /translation="GCGVVGSKVARIMTTHAADLAARIGAPVELAGVAVRRPDKVREGI
                     DPALVTTDATALVKRGDIDVVVEVIGGIEPARTLITTAFAHGASVVSANKALIAQDGAA
                     LHAAADEHGKDLYYE"
     misc_feature    70319..71236
                     /gene_synonym="SCBAC5H2.23; thrA"
                     /locus_tag="SCO5354"
                     /note="Pfam match to entry PF00742 Homoserine_dh,
                     Homoserine dehydrogenase, score 462.40, E-value 3.7e-135"
     PFAM_domain     70682..71224
                     /aSDomain="Homoserine_dh"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00742.22"
                     /db_xref="GO:0006520"
                     /description="Homoserine dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5354_0548"
                     /evalue="6.70E-67"
                     /gene_ontologies="GO:0006520: amino acid metabolic process"
                     /label="SCO5354"
                     /locus_tag="SCO5354"
                     /protein_end="318"
                     /protein_start="137"
                     /score="224.8"
                     /tool="antismash"
                     /translation="PLIRPLRESLAGDKVNRVLGIVNGTTNFILDAMDSTGAGYQEALD
                     EATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLDDVYREGMTEVTAADFASAK
                     EMGCTIKLLAICERAADGGSVTARVHPAMIPLSHPLANVREAYNAVFVESDAAGQLMFY
                     GPGAGGSPTASAVLGDLV"
     misc_feature    70820..70888
                     /gene_synonym="SCBAC5H2.23; thrA"
                     /locus_tag="SCO5354"
                     /note="PS01042 Homoserine dehydrogenase signature"
     misc_feature    71321..71539
                     /gene_synonym="SCBAC5H2.23; thrA"
                     /locus_tag="SCO5354"
                     /note="Pfam match to entry PF01842 ACT, ACT domain, score
                     59.30, E-value 8.6e-14"
     PFAM_domain     71327..71515
                     /aSDomain="ACT"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01842.28"
                     /description="ACT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5354_0549"
                     /evalue="1.50E-14"
                     /label="SCO5354"
                     /locus_tag="SCO5354"
                     /protein_end="415"
                     /protein_start="352"
                     /score="53.6"
                     /tool="antismash"
                     /translation="ISLDVADKPGVLAQVATVFAEHGVSIDTVRQSGKDGEASLVVVTH
                     RASDAALGGTVEALRKLD"
     regulatory      71550..71555
                     /gene_synonym="SCBAC5H2.23; thrA"
                     /locus_tag="SCO5354"
                     /regulatory_class="ribosome_binding_site"
     misc_feature    71639..71652
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.27"
                     /tool="antismash"
     misc_feature    71639..72526
                     /gene_synonym="SCBAC5H2.24; thrC"
                     /locus_tag="SCO5355"
                     /note="Pfam match to entry PF00291 PALP,
                     Pyridoxal-phosphate dependent enzyme, score 310.50, E-value
                     2e-89"
     misc_feature    71723..71764
                     /gene_synonym="SCBAC5H2.24; thrC"
                     /locus_tag="SCO5355"
                     /note="PS00165 Ser/Thr dehydratases pyridoxal-phosphate
                     attachment site"
     misc_feature    complement(72067..72076)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 cgtcgagcag cgggatgacg gactcgccgc cctccaggga gaaccgcttc tggccgacgt
       61 acttggtctg gaggaaggtc tcgaacgcct cggcggcgtt cagccggcgc aggatgcgca
      121 gctgctcctc gcgctccggc ttggtgtgcg agcgctcgat gcggtcctgg atccacttgc
      181 gctgcttcgg gtcctggatg tgcatgaact cgacgccggt ggtgcggcag tacgagtcgc
      241 gcagcacgcc gaggatgtcg cgcagcttca tcagggactt gccggcgaag ccgccgaccg
      301 cgaactcgcg ctccaggtcc cacagggtga gcccgtgctc ggtgatgtcc aggtcggggt
      361 gcttgcgctg ctggtactcc agcgggtcgg tgtcggccat gacgtggccg cgcacccggt
      421 aggagtggat cagctcgaag acgcgggcgg ccttggtgac gtcgtcgtcg tgcgaggcgt
      481 cgatgtcctt gagccagcgg accggctcgt aggggatgcg cagcgccttg aagatgtcgt
      541 cgtagaagcc gttctcgccc agcagcaggt tggcgacctg gcgcaggaac tcgccggagg
      601 cggcgccctg gatgacccgg tggtcgtagg tcgacgtgag cgtcatgacc ttcgagatgc
      661 cgagcttgtt cagggtgtcc tggctggtgc cctggaactc cgccgggtag tccatggagc
      721 cgacgcccag gatgaccgac tggccgggca tcaggcgcgg cacggagtgg acggtgccga
      781 ggccgccggg gttggtcagg gagaccgtga cgccggtgaa gtcgtccatc gtcagcttgt
      841 tgtcgcgggc gcgacggacg atgtcctcgt aggcctgcca gaactcgaag aagttcagcg
      901 tctcggcctt cttgatcgcc gcgacgacca gctggcggtc gccgttgggc ttgaccaggt
      961 cgatggcgag gccgaggttg atgtgggccg gcttgaccag ggtcggcttg ccgtccttct
     1021 cgccgaacga gtggttcatc gtcggcatgg ccttgatggc ctgcaccatc gcgtagccga
     1081 tcaggtgcgt gaaggagatc ttcccgcccc gggcgcgctt gaggtggttg ttgatgacga
     1141 tgcggttgtc gaacagcagc ttcaccggga ccgcgcgcac ggacgtggcc gtgggcagct
     1201 ccagcgaggc gttcatgttc ttcgcgaccg cggcggccgg gccgcgcagg gtcaccagct
     1261 cggggccctc gggggcggcg ccggcgtcct tggcgggcgc ggcggccttc gcctgcggct
     1321 tggcggccgg cttggccggc gcggcggcgg gcttggtggc cggagcggcc ggagccgcgg
     1381 gggcggcggc ggcgggcttc gcgggggcgg gcgccggggc ggcggcctgc ggctgcgccg
     1441 gggcctgcgc ccgcggggcg ggggcggccg gtggcgtgct gccggcgtcc gtgggcacgg
     1501 tgccggcggc ggtcggggtc gccgccgctc cgggcttgta gtcggcgaag aagtcccacc
     1561 aggctcggtc cacggagttc gggtcctgga ggtactgctg atagatctcg tcgacgagcc
     1621 actcattggc accgaacgcg gccgcggggt tctttcccgc ggtgcccgct tggtcggtgt
     1681 cggtcgagat gctcgagtta ctgggggact gtggcgacac ggcgagaacc gccctccttc
     1741 cgcttcttca caagatggtg gacagcggga atcaaggcta cgcctaccga ccccggaagg
     1801 tcagaccggg cccgttcatc gtcgcgtaag tcacattgca gaccgcgttt cggcgctgga
     1861 aatggcggga aacaaccgag gttctgccgc gtgagggatc gggagaccgt gacccggcgc
     1921 ctcgaaaacg cggggccgtg cctgatcaca cgtgtctgcc agcgcggacg cagtggatct
     1981 tgacgctccg cttcgaaccc tacgtcaacc ggacgtcgac ggcaggcccg gaagagtgat
     2041 gaggatgcgg cagccccgct cggattcggc caccccgatc cggccgccgt gcagatccac
     2101 cgcccagcgc gcgatcgcga ggcccaggcc ggtgcccccg tcgctgcccg gaccgtgcgg
     2161 ccgcgacacc gaaccccggt tgaaccgctc gaacacccgg cgccactccg agcgcgggat
     2221 gccgggccct tcgtcgagaa cctccagctc aagcgattcc ggcagctcgc cgcgccgcgc
     2281 ccggaccgtc acccggccgt gcggcgggct gtgcttgacg gcgttgtcga tcaggttggc
     2341 gacgacctgg tggatgcgct cggggtcggc gtgcgcggtc agctccggcg ggaagacgtc
     2401 cagggccagg tgcacgtcgg tgcgggagtg gctgccggac cccgaggcga tgcccgcgcg
     2461 cgcggaggcg accatgttgg cctccttcag cacgcccgac aggtacggcc acacctcgaa
     2521 gcggcgcttg cgcagcggta tgacgccgtt gtccaggcgg gagaggtcga gcagcgtctc
     2581 caccagccgg ccgagccgct cggtctgccc gagcgccgtg cgcatggtct ccgggtcggc
     2641 ctcggtgacg ccgtcgacga tgttctccag caccgcgcgc aggcccgcga tcggggtgcg
     2701 cagctcgtgc gagacgttcg ccaccagctc cttgcgctgg aggtcctggg cctccaggtc
     2761 gtcggccatg cggttgatgg tgacggccag gtcgcccagc tcgtcgcggc ggttctcgcg
     2821 cacccggcgg gtgtagtcgc cgtgcgagat ggaccgggcc accgcgttca tctcgtccag
     2881 cggggcggtc agcgagtgcg ccacgaactg cgtgatcagc agcgtggcga tcatcgagaa
     2941 gaccgtgatg aaccgcagct ccgtcttggt gtgcaccgct atcaccgaca ggccggtggt
     3001 gatcagcacc gacgtgacga ccagcgcgcc cagcttggtc ttgatcgaga acgggcgcac
     3061 gccgccccag ggctccccgg tggtccgagg gccggggttc ctccgtgcgg cttcccgtcc
     3121 tctgctgctc atggcgtcgg cgtctccaag gcgtagccca cgccgtgcac ggtacggatg
     3181 cgctcggcgc cgatcttccg gcgcagcgcc ttgatgtggc tgtccacggt ccgggtgccg
     3241 gaggcgtccg cccagtccca cacctcggcg agcagctgct cgcgggagag caccgcgcgc
     3301 ggggtgttcg ccaggcagac cagcaggtcg aactcggtcg gcgtgaggtg gacgtcctcg
     3361 ctgcgcaccc gcacccggcg ctgcgcgtgg tcgatctcca gctcgcccag gcgcaggatg
     3421 ccgctgcgcg gcgtggaggc ggccaccacg gcccgctcca cccgccgcag cagcacgtgc
     3481 acgcgggcgg ccagctcgcg catcgagaac ggcttggtca tgtagtcgtc ggcgcccacg
     3541 ccgaggccga ccagcatgtc cgtctcgtcg tcgcgcgcgg tgagcatcag caccggcacc
     3601 ggccgctggg cctgcacgcg ccggcagacc tccaggccgt cgaagccggg cagcatgatg
     3661 tcgaggatca gcaggtcggg ctgccaagcc tcggccgtgt cgacggcgga cggaccgtcg
     3721 cccgccgttt gcaccaggaa tccctcggcg cgcagacggg tcgcgatggc gtccacgatc
     3781 gtctgatcgt cctcgaccac cagcacccgg cgctgggcgc cctgggtggc cgtgccgttg
     3841 tgggaggtct gtgtctgctc catcgcccgc ccctgaggtg tgctttccgg aatccgtggg
     3901 gtgatcccat gactgcgctt gacgcttgaa tgatccgcgt cagggcagca gcgtacgggg
     3961 agtcaccgcg cctttgctat ccaggcccga cgccgatgtg cacgacgtcc ggaacgcccc
     4021 gggcaacggg gatctcttcg gtacgcacct gttggaaacc ggcattacgc aaggtttctt
     4081 cgaattccgg agagggctgc gcggaccata cggcgagcac cccgccgggc ctcaacagcc
     4141 gtgcgcagcc cgccagtccg gacggcgcgt acagcccgtc gttgccctcg gtgacggtcc
     4201 agccggggcc gttgtcgatg tccaggcaca gggcgtcgta cgtgtcggat gtctcattga
     4261 cgtactcgac caggtccgcc tcgacgatct ccgcgcgcgg gtcggccagc gcgtcggcgg
     4321 agagcgcggc cagcggtccg gtgcggtgcc agtcgatgat ggcgccctcg cgctcgacga
     4381 ccgcgatccg gccccagcgg gggtcggcgg ccgcgtgcgc gagggagaag ccgaccccga
     4441 gaccgccgat gagcaggtgc ggagcggtcc gtccgccgga ggcggccagc gcgtcggccg
     4501 ccgcgtcgac caggcgccgc tccgaacgcc cgtcggaggt gtccatcagg aagcagccgt
     4561 tcgcgatgat ctggagcaac gtcccgtgcc ggcgcaggac cacctcgcca tacggaccct
     4621 cgcggcggtc cagcacctcg ggggcctcgg cggcctcggg ggagtcgtgg gtagtgaggg
     4681 gcatcggccc atcctggcac ccgctccggc ggaggaatgc gggccggtac ggcggtgctg
     4741 tcccgagagg cgggaaatgc ccccggtact tgatcgctca cagcgaacag ggcttgggga
     4801 acaatcccgg gctccctttc attgagtcga tgtaactcaa cttgactgcc gaaggggaga
     4861 tcatggctgc tgagtccgcc gccttcacac cgctcaccct gcccgtgctg ccgctcgacg
     4921 acgaagtggt cctgcccggc atggtcgtcc ccctggacct gagcgacgcc gaggtacggg
     4981 ccgcggtgga ggccgcccag gccgccgcca ggtccgagcc cggcaagccc cgcgtcctcc
     5041 tcgtcccgcg catcgacggc acgcacgccg ccaccggcgt gctcggcacg gtcgagcagg
     5101 tcggccgcct ggccgacggc gacccgggcg ccctgatccg cggccggggc cgggtgcgca
     5161 tcggcgccgg caccaccggc ccgggcgccg cgctctgggt cgagggcacc cgggtcgacg
     5221 agaccgttcc cgatccgctg cccggccagg tcgccgagct ggtgaaggag tacaaggcgc
     5281 tcgccaccgc ctggctgcgc aagcgcggcg cctggcaggt cgtcgaccgg gtccaggcca
     5341 tcgacgacgt gtccgcgctc gccgacaact ccggctactc gccgttcctg accaccgagc
     5401 agaaggtcga actgctggag accaccgacc cggtcgcccg cctgaagatc gccacccagc
     5461 agctgcgcga ccacctcgcc gagcaggacg tcgccgagac catcgccaag gacgtccagg
     5521 agggcgtcga caagcagcag cgcgagttcc tgctgcgccg ccagctcgaa gccgtccgca
     5581 aggagctgcg cgagatcaac ggcgagcagg agggcgagga gtccgacgac taccgcgccc
     5641 gggtcgaggc cgccgacctg cccgagaagg tccgcgaggc cgcgctcaag gaggtcgaca
     5701 agctggagcg gtcctccgac cagtcgcccg agggctcctg gatccgcacc tggctcgaca
     5761 cggtcctgga gatgccgtgg agcgagcgca ccgaggacgc ctacgacatc cagggcgccc
     5821 aggccgtgct cgacgccgag cacgcgggcc tggaggacgt gaaggagcgc atcaccgagt
     5881 acctggccgt gcgcaagcgg cgcggtgacc ggggcctcgg cgtggtcggc ggccggcgcg
     5941 gcggtgccgt actggccctg gtcggcccgc ccggcgtcgg caagaccagc ctcggcgagt
     6001 ccgtcgccca cgcgatgggc cgcaagttcg tccgcgtcgc cctcggcggc gtccgcgacg
     6061 aggccgagat ccgcggccac cggcggacgt acgtcggcgc gctgcccggc cggatcgtgc
     6121 gggcgatcaa ggaggcgggg tccatgaacc cggtcgtcct gctcgacgag atcgacaagg
     6181 tgggctccga cttccggggc gacccggccg ccgccctgct ggaggtcctc gacccggccc
     6241 agaaccacac cttccgggac cactacctgg aggtcgagct ggacctgtcc gacgtcgtct
     6301 tcctcgccac cgccaacgtc ctggaggcca tcccggaggc cctgctcgac cgcatggagc
     6361 tggtccgcct ggacggctac acggaggacg agaaggtcgt catcgcccgg gaccacctgc
     6421 tcccgcgcca gctggagcgg gccggactgg acgacgacga ggtcaccgtc gacgagggcg
     6481 cgctgcgcaa gctggcgggc gagtacaccc gcgaggcggg cgtgcgcacc ctggagcggt
     6541 ccatcgcgcg gctgctgcgc aaggtggcgg cccagcacga actgggcgag cgggagctgc
     6601 cgttcaccgt caccgagggc gacctgcgct cgctgatcgg acggccgcac cacgtgccgg
     6661 agtcggccca ggacccggcc gagcggcgca ccgcggtgcc cggcgtggcc accggcctcg
     6721 cggtcaccgg cgcgggcggc gacgtcctgt acgtggaggc ctcgctggcc gacccggaga
     6781 ccggcgcggc gggactgacc ctgaccggtc agctgggcga cgtgatgaag gagtcggcgc
     6841 agatcgcgct gagcttcctg cgcagtcacg gcgccgagct ggagctgccg gtgggggacc
     6901 tcaaggaccg gggagcgcac atccacttcc cggcgggcgc ggtccccaag gacggtccga
     6961 gcgccggcgt caccatgacc acggccctcg cctcgctcct gtccggccgg ctggtccgca
     7021 ccgacgtggc gatgaccgga gaggtctcgc tgaccgggcg ggtgctgccg atcggcgggg
     7081 tcaagcagaa gctgctcgcc gcgcaccggg cggggatcac cacggtgatc atccccaagc
     7141 gcaacgaacc ggacctggac gacgtcccgg cccaggtgct ggacaagctc gacgtccacg
     7201 ccgtcaccga cgtccgccag gtcctggagc tggcgctcgc accggcgacc aacggtgcgg
     7261 agcgtgaggt tccggtcgca gcgtgacgga cgcggccgga tgaggcaggg cccgggtccc
     7321 gtgagggggc ccgggccttc gcccgtgggc gaggaggagc cgtcagccgt tggccagcgc
     7381 gacgacgcgg tccagcgcac cgttgaactt gttgtgatcg ccgaccgtcg gaccggacga
     7441 cgtgtactgc cacatcgtgt agtagcccca gccggccggc agcgtgccca ccgtcgaggc
     7501 gtaccgggcg atccacagcg ggttgctggc ggcgaagccg ccgtagttgc cggtgcactg
     7561 ggtccaccag ctggtggccg tgtagatcac ggcgtcccgg ccggtacggg ccttgtaggt
     7621 gttcaggaag tcgcggatcc aggagaccat cccgctctgc gacttgccgt agcaggtggc
     7681 cccgtacggg ttccactcga tgtcgagcgc gcccggcagc gtcttgccgt ccctggacca
     7741 gccgccgccg tggtcgacga agtagttggc ctgggtcgcg ccgctcgtcg tgtccggcgt
     7801 ggcgaagtgg taggcgcccc ggatcatgcc gacgttgtag gagccgttgt actgctgggc
     7861 gaagtagggg ttcgtgtagt acgtcccctc ggtggccttg gcgtaggccc atttgacgcc
     7921 gctgttccac agggtcgacc aggcgacgtt gccctggtgg ctggagacgt cgacgccctc
     7981 cgtctgggcc gcgcggcccg ggacgggggt gccgtgttcg ccgtcgtggg ccgcgacgcc
     8041 catgcccatg tgggcggagc cgcgggccgg gacgtccgcg gcggacgcgg cgtcggcggg
     8101 aagggtgaac acgagggaga acgcggcgag caggatcccg gtgacggcga accgccgtcc
     8161 gcgggccgat ccggatctgt gcacgagcat gacgtgcctc cgatggctcg gtggtgctcc
     8221 gtgggggatg cgcgagtggg gagaacccct ggatggtgta cggatggcgt gcgcatgcca
     8281 tccggaggtc cggtgaagac tctacgcacg tagaaacggc gggtggaaga ggaccgggag
     8341 ccgccgttgg tctaagcctg cgaaatactt ggcgagctgc ggcgatggcg gcccgtggcg
     8401 gaaactttca ggaccggaaa atcgaggcag gggctgacgt gcacgaagac gggaacggcg
     8461 gcggtcgcgg gggcgaatcc cacctgtccg gcagtggtgt gaaccaaccg gagttcctgg
     8521 ccctggagcg ggagctgacc gtcctgctgc ggcgggcccg ggccaaccag ggcgagatgg
     8581 cccgggaggt ccaccccgac ctggagtcgt ccgcgtacgg cctgctcgtg cggctcggcg
     8641 agtgcggcgg ccagcgcgcc accgacctcg ccgccttcat cggcgtcggc aaggccacca
     8701 tgtcccgcca gctgcgcgcg ctggaggaac tcgggctcgt cgcccgtgag cccgaccccg
     8761 ccgacggccg ggcctggctg gtcaccctga ccccggaggg ccaggaacgc gtcggccggg
     8821 tccgggaggc ccgccgcgcc cggtatgccc ggcggctcgc cggctgggac ccgcgcgagg
     8881 tgacggaact ggcccggctg ctgcacgaac tcaaccgggg gatggagaag tagtaccggc
     8941 gccgtccgtc cgtctcacaa ctcggcgtag accaccgtcg cgtcgtcgtg cgtcttgctg
     9001 cgcccgagaa acgcccggcc gtcggccgcg tccgcgcgct ccagctcccg cacccggtcc
     9061 accagggcct gcgcgccctg cttgcggacc agcgccaggc agtccgccca gtcgccctcc
     9121 ccgaacttct ccacccaccg cgcggccccg tccgtgagcg ccgccagcgt ccgcaccgca
     9181 ccgcgcggga gcacccccgt cacggcgcgc gccgccacgg cggggtcggc cgcggccgtg
     9241 aagaagccgc cctccttgtt gcgcagcccg gcgtcgatca ccgcgtcgct cacgagggcc
     9301 gagcggggca gccgggccag ccggtcgtcc aggacggggg tgagggtgcc gtcgggagcc
     9361 tccagcagga gggcggagtc ggacaggacc aggtactcga aggcggccgc ggaccagcgc
     9421 gccaggacca cggttgcctg cggcgtgcgc gggtgagaaa ggtcacaggt ttccgcgtgc
     9481 gccgcggcgg tacgcgcgat gccgcgggac agggcctcgg cgaggggaag atccgggagt
     9541 gaaacggtca gttcggtcag cgctccaccg aggcgcgcgg tgaaccaggg cacggaatgc
     9601 agacagcccg tcgcggtccg tggcggcgtc acaccgtcga ggacgacgag tgaaccaccc
     9661 tgtcccgagg cgggtagtcc gacgctcgcg aagtcctcgt tgggctggtc ggcgaggcct
     9721 ggttccgaga cgagttccgt acgcatccgg ccagtctgca cgagcccttc acagcgttcg
     9781 caaaaggctg gcaccttcct cgggttctcc cggaatcgag gcggcgacgc aggtcaggcg
     9841 ccggatttgg gatggaattc caagatccgt cggtgcgtgg cggcacatag tgccaccgcc
     9901 cgtcgcagac gtccaaccgg ctcgccgggc taccgtgcgg catgcgccgg gggaacttgc
     9961 tcctcaactc ccctccgggg ttcactcctt cgggtggcgg gtcggacgat gcgcgctcac
    10021 cgtccaccgg cactgggagg gtcgggaacc ggtgggggga ctgccccgct cacgcggttt
    10081 ccccgcccga cgcgcggccg cggccgggga acagcccagc gcccggcagt gggtgcacgc
    10141 gcccccggcc ggccagttga cggagcgcca cccgggccca cgggtacacg agtcaggaat
    10201 gcgagcaccg gtgcagaaga cgcggcctcg tcgcacaggc aagcagacgg cccccgtggg
    10261 gagcgcggag cgcacccccg gtacctccac ccctccgcag ccgccggagg ctcccgtcgg
    10321 caagggccgt gccacccacg tacgcaaccg cctcatcgtc gcggtggccg tcgtggccgc
    10381 cgccgtcgcc ggggccggag ccccctcggt cgtggccgcc tccgggcaac tgcacgactc
    10441 ccaggaactg gtgacgctcg ccgagcagac ccagggcgcg ctgaccctcg cccactccct
    10501 ggccgacgag cgcgacgagg tcacccccta catcgcggcc ggccgcccca agtcgaaggc
    10561 gccctccgag cagcgcagcg cccgcgtcga ccgccaggtg gaggagctgc gcgccgacac
    10621 cgacacgccc gcctccctgc gcgaggacct cgacgccgtc gccgcgctgc gccgcgccgc
    10681 cctcaccggc aagagcaccg cgctggaggc ccaccaggcg tactcggagg cgatcaccga
    10741 actccacgcc ctggccgaga agctgggcga ggagatgccg ccccgcgcgg gctccggcgc
    10801 gtacgccctc gccgagctgg acaccgccgt ccagcaggcc gccgccaccc gcggcctgct
    10861 gctggcggcc ctgaacgtgc cgagcaccac cgagaccgtc atcgacccgg tcaccggcct
    10921 gccgaccgag acgaccacct cctcggacgc cgacgccgag cagcgcgacg ccctcgccgc
    10981 cgccgcccag caggcccggg tgcgctccga cgcggccctc gccgacttcc gcgagggcgc
    11041 tcccaaggag gcgcgcggca gcttcgacgc cacggtcgcc ggtcccgagg tcaactccgc
    11101 cgagaagtac ctcgccggcc tcaccgacga gccgacgctc tccgaccgcg acctcggcac
    11161 cagtaccaag cggctggacg cggcgctctc cgcccgcgtc gacgcgatgc gcggtgccga
    11221 gtccgccctg tacgagaagc gcgtcgcggc cctggagcag ttgcgcgacg acgacgtcac
    11281 cgcgctggag atccggatcg ccgtcctcgg cgccctgatc ctgctcgccg tcggtatcgc
    11341 caccgccctg gcccgcaccc tcacccgccc gctgtcggtg ctgcgccgcg gctcggcccg
    11401 gctggccggc gcggcggacc cgacgaccga ggagccggtc gccttcaccg gccgcaacga
    11461 cgagttcgcg caggtcgtcc gctccgtcaa cgccctgcac acgcacgccg ccacgctcgc
    11521 cggacgggtc gccacgctgg agtccgaccg caagcacctg gtcggccagc ggcagaagat
    11581 ggccgacgcc cgcgaggaac tgcgcaccga actcgccgag tccgccgccc agctggaggt
    11641 ggtgcgcaag agcatcggct ccaccttcgt cagcctcgca ctgcgcaccc tcggcctggt
    11701 cgagcggcaa ctcgcggtca tcgagagcct ggaggagcgc gagcaggacc cggaccgcct
    11761 cgccaccctg ttcaagctcg accacttcgc cacggtcatg cgccggcaca gcgagaacct
    11821 cctcgtcctc gccggcaccg agcacgtcca gcacagcgcc tcgccggtgc cgctggtcga
    11881 cgtggtccgc gccgcggtca gcgagatcga gcggtacgag cgggtgcgca tcgccgcgct
    11941 gccgccgcac gcccatgtgg ccgggttcgc cgccgacgac ctctcccacc tgctggccga
    12001 gctgatggag aacgccacct ccttctcgcc gccggacctg cccgtcgagg tctccggctg
    12061 gctcctggag aacggcgagg tgatgctctc cgttcaggac gagggcatcg gcatggccac
    12121 cgaacgtctc cagcggctca acgcccgcct caccgacttc gacccggacg cgccgtacga
    12181 ccaggagggc gaggacggtc tggggctcgg cctctacgtc gtcgcccggc tcgcccaccg
    12241 gcacggggcg cgggtacggc tgcgggagca gaagcagggc ggcgtcgctg ccgtcgtcgt
    12301 cctgccgagc ccgctgctgg ccgccgcccc gccggccgcg ctggccccga ccgtgccggt
    12361 gtccgacggc accggcacct tctccctgcc cggcgccgac gcggaggcca actccaacgt
    12421 cctgcacggg cggacggaga agtccgaggc ggcggagaag tccgagacgg ccgagagggc
    12481 tgggacggcc gagaaggccg agaaggctgg gacggcgggg aagtcggaga cggcggagca
    12541 aggtgccggg gaggacgcgg gccccggtgc cgagccggtc atcgacccgc tggtcgcctc
    12601 ggcggaggaa gccgtacgcc gtgccgaggc ggacgcgtcc cacgcggacg cgccgcagac
    12661 tccggaaccc gacgagcgcg aagacccggc cgggccggtg cccccggaac ccgcgaggga
    12721 gacggtgtcc gcccaggacg gtcccgcccc cggcagcgac ctccccgacg acgccacgat
    12781 ggccctgttc ctcccggccc tcgcggaacc ggagacccgg ccggagaccg accccggccc
    12841 gtacgccatc ggacccgacg cccacgaccg cgtaccggac acggcggagg agaccggcgg
    12901 gcagcaggaa ccggccccgt ccacgcgggc cgaaccggtc accgacaagg gcctgcccaa
    12961 gcggaccccg aagctcacca ccccggccgc ggtgccgcgt ccgcgcacct cgggttccgt
    13021 cgacgccgac gcgctccgcc ggcggctggg cggattccgc cgcggcgcgg aggccggccg
    13081 ccgggacgtc gaggcggaga tcgccgaccg ccccgggcag gaccaggcgc cggacaccgg
    13141 ggcgggcaca accgaagaag ccacgggggg caccgtcgag gaggcaagca gttgaccgct
    13201 cccagtacgt tcggactgag cagtgaagcc cgcaatctcc actggctgct gaccaacctc
    13261 gtcgaggagg tgcccggcat ccggtcggtc gccgtggtct cctccgacgg gctcctgctc
    13321 ctgtcctcgg accccggccg caacgaggag gcccggcagg cccgcgagac gccccgggcg
    13381 ggcccgcgcg gctccgcggc cgacctcgcc accgtcgtct ccggcgtggg cagcctgacc
    13441 gtcggcgccg cccggctgat ggacttcggc ccggtgaagc acacgatggt cgccatggac
    13501 gagggcagcc tgttcgtgat gtcgatcagc gacggatcgc tgctcggcgt gcacggctcg
    13561 gcggagtgcg acatgagcgt cgtggcgtac cacatggcgc tcttcgtcgg ccgcgccggc
    13621 cacgtcctga cccccgaact ccgcaccgag ctgcggaagt ccctggagtc cgagtcgtcc
    13681 gagtcgtccg tgtcgtccga gccgacgggg agcgcccgat gagcagcagt cccggaaaac
    13741 ccggcactaa cggccggggc aacctccccg tccgcggcgc cgaccgcaaa ccggcccgcg
    13801 tacgccccta ctcgctcacc ggcggccgca cccgcttcgg tcacgtgctg ctcgtcgaga
    13861 cgttcgtcgg cgccaccgcc ggcaccgccg cgctcgaagc cgccgaggag cgcagggaac
    13921 tgacgaacgg cggtctcacc tcccgcgtga tgccggagat gcgggccatc gtcgaactgt
    13981 gccgccggat gcgtacggtg gccgagatcg ccgcgctgct gaagatgccg ctcggcgtcg
    14041 tccgggtgct cctcagcgac ctggcggacc agggaaagat ccgtgtgtac ggcaccggga
    14101 ccggccacgg cacgggccgc ccggaccgcg ctctgctcga aagggtgctc agtggactcc
    14161 gtcgtctctg acgccgccgc gttcggcgtc cccccgctcg tcgacaccga cgggcccgtg
    14221 cagccctggc agaccgatcc cacccgcgcg ccggtcgcca cgaagatcgt cgtcgcggga
    14281 ggtttcgggg tcggcaagac cacgctggtc accgccgtct cggagatcac gcccctgcag
    14341 accgaggcgc tgatgaccga ggcgagcgag gagaccgacg acctcaccgc caccccgggc
    14401 aagctcacca ccaccgtggc catggacttc ggccgcatca cgctcgacga cgacctggtg
    14461 ctctacctgt tcggcacgcc gggccagcag cggttctggt tcatgtggga cgacctggtg
    14521 cgcggcgcga tcggcgccgt cgtcctggcc gacacccggc ggctgaagga ctgctggccg
    14581 gccctcgact acttcgagag ctgcggactg ccctacgtcg tcgcggtcaa ccacttcgac
    14641 ggcagcgagc tgttcgaggc ggaggacgtg cgggaggcgc tgacgatccc ggcgcacata
    14701 cctgtcatga tcatggacgc gcgccgtcgg atctcggcca tcgagaccct cttgtccctc
    14761 gtgggtcacg cgctcgacga aacccccgag tagacgaacc cccgaccaga cgccctcgac
    14821 cagacgccct cgaccaggag acggaaaccg catgcggaag atactcgtcg tcggagccgg
    14881 ccagtccggc ctccagctcg ccctcggcct gcagtcgcac ggctacgagg tcaccctgat
    14941 gtccaaccgg accgcggacg agatccgcac cggccgggtc atgtcgacgc agtgcatgtt
    15001 ccacacggca ctccagcacg agcgcgatct ccaactgaac ttctgggagt cccaggcccc
    15061 gaagatcgag ggactcggcg tctcggtggc ggcccccggc tccttcgacc cgggcccctc
    15121 gcagcgcgcg atcgactggc tcggacacct cgacggcttc gcgcagtcgg tcgaccagcg
    15181 ggtgaagatg gccggctgga tggagacctt cgcccagcgc ggcggccagc tggtcatcca
    15241 cggcgcggcc gtcggcgacc tcgactactt ctcccgcgcc tacgacctcg tcctggtctc
    15301 ggcgggcaag ggcgaactgg tgcagatgtt cggccgcgac gcggagcggt cgccgtacag
    15361 cgagccgcag cgcgccctcg ccgtcgccta cgtccacggg atgggcccgc gccccgagca
    15421 cccggagacg gaggccgtgc gctgcaacct ggtgcccggc gtcggcgaga tgttcatcat
    15481 gccgacgttc accacctccg gccgcgccga catcctgttc tgggagggca tacccggcgg
    15541 cccgctggac gccttcaagg acgtcaagga ccctgcggag cacctctccc tgaccctgga
    15601 actcatggag aagttcctcc cctgggagta cgcgcgggcc accaaggtcg aactgaccga
    15661 cgccggcggc accctcgccg ggcggtacgc ccccaccgtc cgcaacccgg tcggccgcct
    15721 ccccggcggc ggcgcggtcc tcggcgtcgc cgacgtggtc gtcgccaacg acccgatcac
    15781 cggccagggc tccaactccg cgtccaagtg cgccgcctcc tacctcgcct cgatcatcga
    15841 gcacggcgac caggagttcg acgagacctg gatgcggcag accttcgacc gctactggga
    15901 gacggcgcag cacgtcacca agtggaccaa caccatgctg gccccgccgc cggagcacat
    15961 cctcaacctg ttcggcgcgg cgacgcagct ccagcccatc gccgaccgtt tcgccaacgg
    16021 cttcaacgac ccgtcggact tcgagaactt cttctacgac ccggcgaaga ccgagggcta
    16081 cctggccgag gtctcgggcg ccgcgggcgc gtaggaggcc gcgtacccct cgtcggaccc
    16141 gttcgtcgcc ccggcgggaa gcctcggcgg cgtgtagcgc aataccggct ccccgccggg
    16201 gtcggggcgt acggcgccca ggaccgggtt ggcggcgatc ggcgacacct tgacgtcggc
    16261 gccggggcgc ggtgcctgga cgaccatgcc gtcaccgagg tacatcgcca cgtgggtggc
    16321 ctcggggaag tacacgacca ggtcgccggg gcgcagctcg tccagcggca cgtggtcgag
    16381 gcgggcccac tgctcctggc tggtgcgcgg gatcggcgtc ccggcccgct cccaggccac
    16441 cgaggtcagc cccgagcagt cgtacgacgc cgggccctcg gcgccccact ggtacggctt
    16501 gccgagctgc tccaccgcga agcgcaccgc actctcgccc ccggcggacg gcttggcgtc
    16561 gtcgccgagc gcgccggacg ccaggaaccg ctcctgctcc tcggcgatcc cgctcttctc
    16621 cagctccgcc agggcggcca gctgctccgg ggtgagggag gcgagcagct cctcgacggc
    16681 gcgcaggcgt tcgcgcacgc cgtcccgttc cctctcctgg cgctcggcga gggcggcctg
    16741 ccgggccagg gccgcgcggg cccgcccggc cagctcgtcg gccttcttcg tgtcgccggt
    16801 cagccgcccc accgtctcgg cccgctcctc ggacagcctg ccgatcacat gcccctggtc
    16861 gagcgcgtgc tgcgggtcgc gggcgagcag cagccgcaga tagggggaga agtcgctgct
    16921 gttctggtac tgctgccggg ccagccgccc ggccgcgcct cggctgtccc gcagcgacag
    16981 ccgggtccgg gtcagctccg cgttcagccg cagcacccgg gcgcgctgcc gcttcagccg
    17041 ctcctcggtg ccgttgtagg tctcggtggc ccgctccgcc tcccggtaca gccgctggag
    17101 gtccgtcagc agtccggcca cggtacggtc gccggccgcc ccctcggccg gtccgggtcc
    17161 gggtccgggt ccggccgcgg cgggcacggg cgcgaggacg atcccggccg tgagcgccgc
    17221 cgtacacacc agacgcagca gccttcctga cacgccatca cctccgctgc ggggcggcgg
    17281 gtccgctccg cacggtgagc atgtggcggg tcggcgggct tcgcgcgccg agtgtgcgcg
    17341 gatcggcgca acggggtcac ccgtccgcgt cgtccggctt gccacccggc gtggcgtctg
    17401 gctcggcggc cgacggacgc tccggtttcg accagggcca cttccggccg gagcccttcg
    17461 ccccctcggg ggcgtacgcg tacttccagc gggcgaaccg cagcccgccc cgggagtcgc
    17521 ggggcacgcg ccggtagacg agcaccgtgg gcgggccgcc gtccgggtcc ggcacgggga
    17581 tgcggtacgt cttcgggggg tgcccggtca tgccgaccag gacgggcagc acgcggccgt
    17641 ccatggggcc gccctcgaag ggggtgtctt cgctcttcac ggctccagtg tcggtgatcg
    17701 gggcccgggt gccggaagcc gtcgtccccc tgtcgggccg ccgcccggtg tcagaggtcc
    17761 gccgccagcg tctcgaccag cgccgcgctc tgcgggtcgc ggcgggcggt gaccgtcagt
    17821 acggcgagga actgctccac cagccagtcc cgcagctcgt cgaagggcgg ctgcttgtcc
    17881 tcgtccagcc agatcagcga ggccgcctcc accgccgtga tccacatccg gacggtcatc
    17941 cgcagccggg ggccgggctc ggcgacgtcc aggtggcgca tgatgtggtc ggcggcggcc
    18001 cggcgtacgc cgtccacgat gcccgaggtc tgcgaggtct cgaccacgct gccgccgcgc
    18061 agcagggcgc tgaagccggt gtcgtgctcg tcgacgaagg tgaggtagcg gtccagggcg
    18121 cgggagagcc gggccagcag cgggcccttg cggggttcgt cgaagcagag ccgcagctcg
    18181 tcggcggcgg agctgagcgc ggcctcgtac agctgctgct tgccgccggg gaagtaccgg
    18241 tacaccagcg gccgcgagac ccccgcctgc tcggcgacgt cgtccaggga gacctcctcc
    18301 gggggccggt gcgcgaagag ggcgagcgcc gcgtccagca actggacgcg gcgctcctcc
    18361 acgctgaggc ggcggtaggc gggggtgggg gcctgcgggg tcatgaaccg cagcgtaacc
    18421 cgcacgaccg ggcatccacc cacgtcggcg aggcggaccg gccgaaccag ggcctgtccg
    18481 gcggatcatg ccgcagacgc ggggtctggc acgcccatct gcggcgttgt cgtcggttgc
    18541 cgactccccc acgctcgact gcgctcgcgc ggggggaccc ccatcgcgtc gacgccctcc
    18601 tccgccttgc agctgcacgc accagacccc gctcaccagc gacaatgagg tgccgtgtct
    18661 ttcctgcgac ctgatccgcc ggacaggccc taggtcgtgt ccgtaaagtg ctgtggtcgt
    18721 tggtctgttc gtggtgcgtc gtcatgagct gactgatgag tcgtgggcgg tgatcgagcc
    18781 gtttctggct ccgccgcgga tgggtcgtcc ggtgcgggat cgccggcagg tggtcaacgg
    18841 gatcctgtgg aaactgtcca ccggggctgc ctggcgggac ctgcccgagc ggtatggccc
    18901 gtggaagacg gtctatgaac gtttccgccg ctggtctgcc gacggcacct gggaccgcct
    18961 cctggcccac gtccagcagc actcggacgc ggccggtgcg gtcgactgga ccgttgtctg
    19021 cgtggactca acgaccgtgc gggcccatca gcatgccgcg ggagcccgaa aaaggggcag
    19081 gactggccgg gcgaggcact cggccggtcc cgcggcgggc tgaccacaaa gatccacctc
    19141 gcctgcgacg gtgaaggccg ccccctggcc ttcaccctca ccgccggcaa cgtcaacgac
    19201 tgcacccagt tcgagcaggt catggcccgc atccgcattc agcggtgcgg acccggcaga
    19261 cccagaacca ggcccgagcg ggtcgcggcg gacaagggct actcgtccac gaagatccgc
    19321 acctacctgc gacgtcgcgg catcaaggcg gcgattcccg agcgcatcga ccagatcaac
    19381 ggccgcatcc gcaggggcga gagcctctgc cgactcgacc gggcggccta ccggcgacgc
    19441 aacgtcgtcg agcgctgctt caacaagctc aagcacaaca aagccctggc cacccgctac
    19501 gacaaacgcg cccgtcacta ccaggccctg gtcaccctgg cctgcctcaa actctggcta
    19561 ccctgacttt gcggacacga cctaggccag caggcccgag gaccgccaca gcttgcggcc
    19621 ggcgccgcgc aggacgccga tgtcgtccag gaagtcggtc aggcgcttcg cgccggtctg
    19681 catgatctcc ttgcggtggc cactggcccg gacctgggcc agggcctccc gcttgtccag
    19741 gccgacgttc gtgtagacct cggggttgat gaaggccttg gagaagacgc gggcgaactc
    19801 gccggaggtg acccgggtga actcctgcga ccacttcggg gccgtcacca tctgccggcg
    19861 cagctcctca cgggcgtacc gcacgtgccg ggcctcctcc acgacgtgga tgcgcgtgac
    19921 gccccggatc agcggctgga cccgctcgtc cgggaaggtc aggcgctgca tccagtccag
    19981 gacctcctcg ccgagcagcg tggcggtgaa ggagccgggc gtggtggaga tcgtcttgaa
    20041 caggcgcccc aggtgctggt ggaccgggct caccggatac cacggggtct ccccgcgcga
    20101 tatcagccgg gcgaacatct tcgagtgccg gcactcgtcc tcgatctcgg tcagcgcgta
    20161 gcgcacgtgg gcgctcgtcg ccgccttgtc gtagatgtgc cgcaccagga gctgcatcag
    20221 gatcagctcg aaccagatgc cgagcgaggc gagcgcggcg gcctcgtgct gggagagcgc
    20281 gatgcgctgc tcctcgctca tccgctgcca catcggcgtg tcgtacagcg acaccagctc
    20341 cggcggccag aaccacttgc cgtcctcgaa cggcgcgtcc cagtccagct ccttgtccgg
    20401 gtcgaaggag tgcttggcgg acgagtcgag cagccgttcg gccacctgct cccggtcctt
    20461 gagcaggccg agcgcgtcgc gcaggccctc gagcgcgtcg gcttccgtca gggtcgtcat
    20521 ggctgtgtcc cacctcgtcg aacggatcgt gttacccgcg gtcactccag cttgctccgt
    20581 cttatgagac tgcgtgtcag taagctcgtc aatcccctgc gcggaacttg ttgaccgcga
    20641 gtaaagaagt gagaggtgtt caggtcctca gaccgagcag tccagcccct ccggcacctc
    20701 gcccgggacc ggctccgacg ccccggccgg gtaggacgtc cgcagggtga aggcgtacgg
    20761 cgtggggccg tgggtgcgca ggtggcgcag gcgggactcc gcctccgcga ccgtcgggcg
    20821 gtggcccgcg ggcacccacc acagggcggt gacggcctcc gccggccgct cgaaccactc
    20881 gcgccgccgg gccagcatct cccggtgccg cccctggtac atgaacgccg tcagggcgtc
    20941 cgcgtcccgc cacatggtca ggttgacgat cagccaggag tccccgaaga ccgggatgtc
    21001 ggtggcgtcg ccgccctcgc tctggagccg ccacacgaag ccgtccgccg cgtcggccgc
    21061 ggcgttcacc ggttcgagcg cgtccacgaa gtccttcaac tgcggtgagt ccagcggggc
    21121 cttgaggcgg gcgatgttga cctgggcgag ttcgtgcacg gcgtcttcag tcatgtaccg
    21181 aacgttaggt cgggagcttc ggccggcggt acccccgtct catcccccga gcaccgcctc
    21241 catcaccgca cgcgcgatcg gcgccgccag cccgcctccg ctgaccccct gccggtccga
    21301 cgccgtgccc tcgaccacca ccgccaccgc gaccttcggc tcgatgtccc cggcgccccg
    21361 cgcccaggag atgaaccacg cgtacggcgt gcccgagttg ccgacgccgt gctgggcggt
    21421 gccggtcttg ccgccgacgg tggcgccggg gatcgccgcc ttcgcgccgg tgcccttgtc
    21481 caccacgccg gtcatcagct ccttgagcag cgcggccgtc gaggggcgca tcacctcgcg
    21541 ggagggccgg gacccggccg ccgccaccag gctgccgccc gcccgcagcg tccgctccac
    21601 caggtacggc gagcgcacct ggccgccgcc cgccaccgcc gccgccaccg tcgccatctg
    21661 cagcggcgtc gcccgggtgt tgtactggcc gatcgacgac aggccgagct gcgcccggtc
    21721 cacgctggtg tcgaaggtgc tccgtgcgac ggggaagggg acccgcagtc cgtcgtcgtt
    21781 gaagccgaag gcctccgcca tcgccgtcat gccgcgcacg cccacgtcca cgccgagctt
    21841 ggcgaacacc gtgttgcagg accactcgaa cgcctcccgc agcgaggcgt tccggcaccc
    21901 gtcggcctcg ttcgtgagct tcgtccgcgt cccgggcagg gtgtacgggt cgggggagcg
    21961 ggtcggcgcg tccaggtccc ggatcacccc cgcctccagc gccgccgccg cggtgaccac
    22021 cttgaacgtc gaacccggcg gataggtccg gctcaccgcc cggttgagca tcggcttgtc
    22081 ggggtcggcg ttcagccgct tccaggtgcg ggtggccgcg gcactgttgc cggagagcaa
    22141 ctgcgggtcg taggaggggg tggagaccag ggccagcacg cggcccgtgg ccggctcgat
    22201 cgcggccacc gcgcccttgc gcccgccgag cccctcgaag gccgcccgct gcgcggcccc
    22261 gtggatcgtc gtcaccacgt cgccgcccgg gttgtgggcc cccgtcacgt cgttccacag
    22321 cggcagcggc gcgagcatcg ggtcggcgcc ggacagcagg ccgtcctcgg cgtgttcgag
    22381 cagcgtcgtc ccgtacgcct gggaggcgaa gccggtgatc ggcgcgtaca tcggcccgtc
    22441 ggcgtaggtc cgctcgaagc gcaggtgctc accggtgtcc cgggagccgg tgaccgcccc
    22501 gccgccgacc aggatgtcgc cgcgcggctg ctggtagcgg gcgatgtcgg ggcggcggtt
    22561 ggccgggttg tcgtcgtact ccggcttctg gacgatctgc acccgggccg cgttgaccac
    22621 cagggcgacc agcagcaggg cgcagaagac ggcggcgtgc cggatgttcc gggtcaccgc
    22681 agctgccccc cgctcacggc tccgcccgcc cgccggcctg gctgcgggcc gcgtggctga
    22741 cccggatcag cagcgccacg atcgcccagt tggtgacgac cgaggacccg ccctgcgcca
    22801 ggaacggcat cgccatgccg gtcagcggga tcagcccggt caccccgccc gcgatgacga
    22861 acacctggag cgcgacgatc gaggagagtc cgaccgcgag cagccggccg aaggggtcgc
    22921 gggcgccgag ccccgcccgg tagccgcgct ccaccagcag cccgtacagc aggaagacgg
    22981 cgctcaggcc gaggaagccc agctcctcgc cggccgtcgc caggatgaag tccgacttga
    23041 cggcgaagcc gatcaggacc gagtggccga ggccgagacc ggtgccggtc accccgcccg
    23101 ccgcgaaggc gaagagggac tgggccagct ggttcgggcc gtggcccgcc tcgatggacg
    23161 cgaaggggtg cagccagtcc tccaccctgc tgtgcacgtg cggctccagc cagcccacgg
    23221 cgaccgcgcc cagcgacgcc agcagcagcc cgacggcgat ccagccggtg cggccggtgg
    23281 cgacgtagag caggaccacg aacaggccga agaagaggag cgaggtgccc aggtcccgct
    23341 ccaggaccag gacgccgacg ctgaccagcc acaccgccag gatcgggccg agcacccggc
    23401 cggtgggcag ttgcagccgc cacacccggc ggcccgcgta ggccagcgcg ctgcggttgg
    23461 cggccaggta ggcggcgaag aacaccgcga gcagcacctt ggcgaactcg ccgggctgga
    23521 tggagaagcc ctcgatccgg atccagatgc gggcgccgtt caccgccggg aagaagatcg
    23581 gcacggtgag cagggcgagc gccgcagcga cgcacacgta ggcgtagcgc tgcaggaccc
    23641 ggtggtcgcg caggagcagg acgaccacga tgaacagcgc gacacccagc gtcgaccaga
    23701 ccagctgggt cggggccgcc cggtcgccgg gggtctccag gtcgagccgg tagatcagca
    23761 ccaggccgag gccgttgagc agcaccccga tgggcagcag cagcggatcg gcgtacgggg
    23821 cgcgcagccg taccgccagg tgggcgagga gcgcgagcac cccgagcccg gcgccgtaac
    23881 cggcggcgcc gggaggaagg gcgtcgtgct gggcgaggcc cacgttgcag tagccgaaga
    23941 ccgacagcag gacggccatg aggatgagcg cgagttcgat gccccggcgc cgggggagcc
    24001 gggcgacggg agcgggggtg tccgcctgtg ccacggtgat cccggttccg gttccggcct
    24061 tggtcatgtc cggaacttac ccaaatggtg tggtgtgcgc ggcgtccggc tcagcaccag
    24121 cgcggcgcgg ggccgatgtt gtcgatgtac cgggccgccc cccaggccca ggtgccgtcc
    24181 gtgaggaggt accacagcgg gttgccctgc accctggagc cgggcgtctt gcagtagatg
    24241 gagacgacct cgccccggcg ggcgtaccgg atgacgtccg caccacgact cggcgaggtg
    24301 cgcagcgcga gccggtcggc cgtcacgaca ccccggtagc ggccctgctc ctggcggccg
    24361 tcgctcccgc cccacgcgcc gccgccgctt cctcccccgt ctcctcccct gttcccgccg
    24421 ccggtgacgg cggacgtgga gccggcgtcg ccgccccact cgtcgttcgc ggcggcgggt
    24481 gtgacggcga cggcggtggc gagcgcgccg gccgcgaggg cggtggcgag gccgcggacc
    24541 aggggcgaac gcgaggccgg tgcggacagt ggcgacatgg gagtacctcc cgggagcgaa
    24601 cgggtcttca ggtgactaac cgccacatta ggagcgcccc gcaggccccg cccgccgcac
    24661 tgagccatcg gggaagacgc cgtggtcagg gctgctgagg cagcgtcagc cgggccagcg
    24721 caccgccgtc cggcggattg gtgaactcca gccgcgcccc gagcacctcg gcctgcccca
    24781 gcgcgatcgt cagccccagg ccgtgcccct tcgccccgcc ctcggtgcga aagcgctgcg
    24841 ggccgtgcgc gagcaggtac tccggatagc cgtccccgtg gtcccgcacg gtgatcaccg
    24901 caccgtccac ggtcagcacc accggcgccc gcccgtgccg gtgggcgttc gcgaccaggt
    24961 tgcccagcac ccgctccaga cgccgccggt cggtctccac ccgcgcgtcc cgtacgacgt
    25021 ccacgcgcgt gtcggtgccc gagccccgca ggacccgccg gaccagcgcg cccagctcct
    25081 ccggctccgt cgccggccgc tcccgcccgc tctccagccg ggagatctcc agcaggtcct
    25141 cggtgagcgt gcgcagcgcc gccacccggt cccgcaccag ctcggtgggg cggcccggcg
    25201 gcagcagctc ggccgccgcg tgcagtccgg tgagcggggt gcgcagctcg tgcgccacgt
    25261 ccgcggtgaa ccgctgctcg gccagcagct tgccctgcaa cgacgaggcc atggagtcca
    25321 gcgcggcggc gaccgacgcc acctcgtcct gcgggcgcgt cggatcctgc gcgcgcggat
    25381 cacccacccg cgcgtcgagg tcgcccgcgc tgatccgccg tgccacccgc gccgtcgtgt
    25441 gcagccgccg cgtcacccgc gtcaccgcga acgcgccgac cagcagcgtc gccccgatcg
    25501 ccagcgccga cgaccacacg agcgtgccgt ccaggccgtc gatggtggcc tgtccctggg
    25561 agtggtcgac ccgcaccgcc agcgcccggc cgccgtcggc cggccccgcc gcccacatcg
    25621 tggggcgccc cgcgtactcg gcgagcatcg tgccgcgccg gcccgaggcg gccagttcgc
    25681 gcagctgccg cggcagcccc gccggatcga tgccggcccc gcgccgcagc ggatcccccg
    25741 cctcgtagga ctcggtcgcc tcgcccagcc gggacagggc cgcgtcgcgc gcctggccga
    25801 cggtccggtt ggtcaccgag acgtgcacca ggacgccgag cagcgcggcg agcccgcagc
    25861 acatcacggt gatgaagacg gccgccttca cggccagcgg tccggtccac cgagggaggg
    25921 cgagcctcac cgggcgctcg ccgagggcga cgcggacggt gcggccgggg gcgacgaggg
    25981 tggtgcggcc gagcgcgaca cggagggcga cggcgaggcg gagggacgcc tggcgtgccg
    26041 tccgccgtcg tcggtgcgca gcatctcgtc gctggtcagc agcatggccc gctggtcggc
    26101 gtcccaggtc cactgaaggc ggtactcgta cccggcgacc tccgagggcg agcggacgat
    26161 caccgtgcgc ccggccagct cgaccgcgct cacggcgtcc tcgtaggaca tgatccgcac
    26221 gagccggtcc ttctcgacgg tgtagacccg cacggcggtc agccggtccg gcagcagccg
    26281 gaaacccagc gtcatctcgg gacgcccgtc cccggtcagg tcgcggtagt acggccgcag
    26341 caccgggcag ccgccgggct cgtccccggc accgtccgcg ccgcagtccg ccatccgcgc
    26401 cgacgtctcg tggtaccgcg ccccggcgcc cgcgtagtcg tccgggtgcg cggcgatctc
    26461 ggcccgcacc gcggccaccg ggtccgccct gcggatgtcg ccaccgggca cggcgacgcc
    26521 cttcatcggc gcgtgctcca cctcgccgat gtcgtacgcc ggactggacg ccggggtcag
    26581 gccgggccac agccgggccg gatggtgcgc ggcgggcgtc gccccggcac tctccaggcc
    26641 gccggtgtcc ccgcaggccg ccagcacgcc ggtcgcggcg gtcgccagga gcagcgcgag
    26701 ggcggcgggg acgcgggcgg ggcgcccgcg gcggctcggg agcactgcac tcctggggtt
    26761 cgggggatcg gcgtcggcgg tcccgcacgg ccgcgggcgg caccgcgggc atcgcggcac
    26821 cgcacgcgac gccgtacgga aggccatttt gcgtgcgcac gggcccgccg ggctactcgg
    26881 ccggttcctc cagcagccgc acggtggcca ggccggtccg gagataggcc acgaacagct
    26941 cgttgtgcag cgcccacggc gagcgccggg cccggaccag ccggatcgcc tcctcggcgc
    27001 cgctgccccg gcgcatcagg gtgtgcgcga cgacgagacc ggagcggttg tacccgtggt
    27061 agcagcggac gaggaccttg cggccgccgt ccagcgcctc gtccgcggcc cgggccagcc
    27121 ggatcacccc ggcgagctgg gtgccgtcca ggggcccgtc cgggatcggc cacacatggt
    27181 gctcgacgcc ttcgtccggc ccgtgcccgg gcagccgcag cagcgtctgc acgaggtcga
    27241 actcgtcccg caccacggcg aactccagcc gccccggcgt gggccggaac tcgtgcccgc
    27301 ccatccacag gcccggcacg atctcgtccc agggccggtc cggagccggc acgtccggac
    27361 ctttcccacg ggtacgcaca gccacctccc agtcccgccc agggtctgcc caactcgtcc
    27421 cgaaagcaac cggcttcttg ccctcgcggc acctcgcctg ctcccatgga cgggggtggt
    27481 gatggcatgg acggactgcg cgtcgtgccg acccggcgcc acggccggga acggctctac
    27541 gtctgcctcc cggacggcgg gaacgtcgcc tggtacgacc gcgaggaggc ccgcgtcagc
    27601 ctgctgagcg acgaccgcag ggccgaggtg ctccaggccc tcgccccctt cgtcaccggc
    27661 ccggtcacgg tcggcccgcc gccggtcccg accccggccg agctggcccg gctcaccctg
    27721 caccccgacg acgacctggc ccccaaccgg cccggcgagg ccctcctggt cgccctggaa
    27781 cgcgcgccgg gaccggcaca ccggctgcgc cccgacccgc gccgccgggc gctggccgcc
    27841 gagcaggcca ccgggaccgc cctcgaccgc ctcgacggcg ccggcctgca caccctgcac
    27901 tccctcccgc tgcccggcgg cgaccgtatc caccacctgc tgatcgggcc cggtggtctc
    27961 ttcgccctcc acgtgctgcc cgcccgcgga caacgggtgc gggtcgccga cccgctggtg
    28021 gcgctgggcc gccggacccc ccgccccctg ctggaccggg tccgcgccga cgccgaccgg
    28081 gcctcgtacg ccctgacggc cgaggtccac ccggtgctcg tcctcgccgg gccggcgcac
    28141 gtgaccgtca ccgccccgcc ccgctcggtg cgcgtcctca cggaccggga gctgccggac
    28201 ctggcccgga cgggcggggt gctgaaaccg gcggacgtgg aggccctgca cgccatggcc
    28261 cgggaccggg ccacctggca gggcgtctga gggcacgccc gcttccgagg tccgtccgcg
    28321 tccgaggacc cgtccgcctc cgaggtccgt acggcgtccg gggtccgtcc gagggcccgg
    28381 ctcagggcag cgccgccgcc cgccgccggt cgaacagcgg ggccagcagg tcgccgtggt
    28441 cccgcacccg ccgtccgacg tccggcgtca ggaagacgaa ccgctccgcc cgcccgcacc
    28501 cggcgacctc ctcccacgtc accggcgtgg agaccgcggg cacgccgcgg gcgcgcacgg
    28561 tgtacggggc ggccgtggtc ttgcgggcgg cgttctggct ccagtccacg aacaccttcc
    28621 cgggccgcag gctgcgcgtc atccggtgca ccaccagctc cggcagcgcc cgctccgcct
    28681 ccacggcgag ccccttcgcg tactccgaca cccgctccga ggacgcgccc cgcacccccg
    28741 ccagcaggtg cagccccttg gccccggagg tcttggcgta cgcctcgatc ccgtccgccg
    28801 ccagccgctc ccgcagccac agcgcgacct cgcagcactg caccacggtc gcgggcggcc
    28861 ccgggtccag gtcgaacacc agccggtcgg cctcgccggg atcgtccacg gtccactggt
    28921 gggtgtggaa ctcggtcacc aggttcgccg cccacatcag gctcgccagg tcctgcacca
    28981 gcaccatccg ggccgggccc tccgagcggg gcacctcggc cgtggtgacc cagtcgggcg
    29041 taccaggcgg cacgttcttg gtgaagaaca cctggccgtc cgggccgtcc ggataccgca
    29101 ggaaggagac cgcgcggtcc cgcaggtgcg gcagcagcac ctcggcggtc gtcgcgtagt
    29161 agtgcagcag ctcgcccttg gtgaggccgg ccgcgggata cagcaccttg tccaggttgc
    29221 tgagggccac ccgccgcccc tccacttccg tcatcggcgc cataccatga gaatctcatg
    29281 aaacagtcac aaaacgcccg aaaggaacgg tgctgcacgt gcgatccatc tggaacggcg
    29341 ccatctcctt cggcctggtc agcatcccga tcaagctggt gaacgccacc gagagccact
    29401 ccgtctcctt ccggcagatc cacacggagg acggcggccg gatccgctac cgcaaggtgt
    29461 gcgaactgga ggaccgcgag gtcacccagg ccgagatcgg caaggcctac gaggacgccg
    29521 acggttcgat gatcccgatc accgacgagg acctgtccca gctgccgatc ccgacggccc
    29581 gcacgatcga gatcgtcgcc ttcgtgcccg aggaccgcat cgatccgctc cagatgggct
    29641 ccgcctacta cctcgcggcc agcggcgccc cggccgccaa gccgtacacg ctgctgcgcg
    29701 aggcgctcaa gcgcagcaac cgggtggcga tcgccaagtt cgcgctgcgc ggccgggagc
    29761 gcctgggcat gctccgggtc gtcggcgacg ccatcgcgat gcacgggctg ctgtggccgg
    29821 acgaggtccg cgcccccgag ggcgtcgccc ccgaaggcgg ggtcaccgtg cgcgaccagg
    29881 aactggacct cgccgacgcc ctcatggaca ccctcggcga gatcgacctg gacgacctgc
    29941 acgacgagta ccgggaggcc gtcgaggagg tcgtcgccgc caaggcctcc ggcgagaagc
    30001 ccccggaggc ccgcgaggag gcggcgcccg ggaaggtgct cgacctgatg gcggcactgg
    30061 agagcagcgt gcgggcggcg cgggagtccc gggacggtga gggggcgggc ccggcggagg
    30121 aggcggaggt caggtccctg tcgcggcgca agacctcgtc ccgggccccg aaggagaccg
    30181 ggggcaagaa gtcgacgtcg acggccgcga agaagacggc ggcgaagagg gcggagccga
    30241 agaagtcgac ggccaaggcc gccgggtccg cgaagaagac ggcggccggg agtcctgcca
    30301 agggcaccgc caagaaggcc acggccagga gcacggcccg cagcggcgac aagggcgcgg
    30361 ccaagagcac cgccaagaag acggcgtccc gcaggcgcag cgcctgaccc ggagccggcc
    30421 gccgcgcggt cagccgaagg tccgggtgga cgcgggcgcc cggggtatcg cggacggggc
    30481 gggttcgaag gcggcggggc tcgcgccggc ggactccgcg gacgccggcg tgtccgccac
    30541 ggaggccggc gagggcaggg cggggctttc ctccaggcgc tgcccgatcg tctcggcggg
    30601 gccgccgccc ggggtggccg gtccggtggt cagctgcgac cacgcggtca cggcgagggc
    30661 gaccgcggcc gccgtgccga gcacgcggcc cgtccgccgc agccgggccc gcccgtccag
    30721 ctcgcgccag gccggtccgg cccacgcgtc ctcccggcgc cacggctcac cgaccgtgtc
    30781 gtgggcgcgg ccggggtggc cggagcagtc ggcgggaggc tccggccgcg tgcggccggg
    30841 gatccggtcc cgtgcggcgg gttcccgggg ggcggaggcg tggatggcgc gctcgtcgtc
    30901 ctccaggaac agtcgccaga cgtactcggg cacgaccggc gcatcgtccg gtccgtccgg
    30961 ggtgtcgccg ccgcccggtc cggaagcggt catggtcccg ctcctcctgt cgtcggctcc
    31021 ggacgggcgc gggcgggagc aggggaacgg ccgcccacca ccggctccgg cgccggatgg
    31081 tcatggcccg gcggacaccg tcgcccgcca cctgcgaaga acgtgcgcgc gtggcggccc
    31141 gttccccgtg ccgccggtcg tgactgggtc gtaatcggtg accgtgcccg cgtcgggttc
    31201 gcgcgccgcg cgccgcgcac cgtgcccgcg tcgggttcgc gcaccgcgcc gccgcgcccg
    31261 ggccccgccc cccccgggtc ctcagggagc cgccggggac ggggcgggcg tcggggaggc
    31321 ggtgttcacg ttcaggtcgg ggcgcggctt gagcaccagc acccgctcgc cgggctgcgg
    31381 cgggggcggg gtgaccttct ccctcggcag cttcgccggg cccgtctgct tgaaggtgac
    31441 gtcgtcgtac tcgaccagcc cggtcttctc cagcaccgtg atgtggtcca ggacggtgtc
    31501 gttggccagg tccgccagct gccgcacgag ggtgttcttg gtggaggccc ggatcttggc
    31561 gatggccggg aagatctgac cgtgggtcac ccgcatgatg ttgaccgccg aagagtcgaa
    31621 ctccctgccg ctctcggcgt ccacggcggc cacgaagccc tcctgctgcg gggaggcccg
    31681 gttgggcagc gtgatgccca gctcggggga gatctcgcgg cacatcgcgt cgagtccggc
    31741 gtgcccgacg accaggtgct ccccggccgt cttcatcgcc ttcgtcgtgc cgcgctccat
    31801 caccatctcg cccagcgggt actcccacag tccggcggcg cggaccttca ccacgaagtc
    31861 gcggtcggcc tcggtgagcg gaccgaactt cgtactggcc accacccggt tctggttgcc
    31921 gtcggccttg tccagaccga gcacggccgg gaaggccagc gcggtgaggg tcagggtcat
    31981 cgcaccgaac aggacgacga ctccgatcct gctgcgggac aggcgcatgg tgcctccagg
    32041 ggcgacgcgg ggacgcgagg tacgcgcacg tgtgctcgtg cgcgtaccgg tacgccagga
    32101 agtacggaag cggcggccgg atccttcacc gcttcggcac ggaacttgcg ggcccggcga
    32161 gggacccgct cccgggccgt cgccgcgccg gtcagccgat gtcggcgccg tacacgcgct
    32221 cgaccgtgat ggtgagcagc acccggcggt cggacaccat cgtcgaccgg tactcgtccc
    32281 agtccgggtg ctccccggcc gcggcgcggt agtactccac cagcgcttcg acctccggtc
    32341 cgtgcgggtc ggcacccgga ccggtgaggg tggcgacgcc ctcggcggtg gcccaggacc
    32401 tgccgtccgg agcggtcacc tccagtgcgg cccgcgggtc ccggcgcagg ttcgccgtct
    32461 tggcgaggcc ctcgcgggtg gagacccgga tgacgcccgc ctcggggtcg taggcgggca
    32521 tgacgggcga gagctgcggg cggccgtccg acttgatcgt cgccagtacg ccgagccggc
    32581 tctcggccag caggacacgg ggatcgaagc gcggtgtggt ggtcatggac cgatcatcac
    32641 ccggaaacgg gctcaggaca ccgccgggcc gcccaggtag tcgcccttct cgtcgtaggg
    32701 ccaggcgttg gccacgcatc ccttgaggcc cttgatctgc tgcatcatcg ccggagcggg
    32761 ccggccggct ccggggcacg tctcgtggcc gtggccgatg cggtgaccga cctcgtggtt
    32821 cacgatcagg gcccggtact cgtggatcgg cccgtcgaac tccggggagc ccagcaccca
    32881 gcgcttgagg ttcaccacga cgtccgtgcc gacgctgcag ttgacctcgc cccgggtgag
    32941 caggcccgcc gcgccgcaga tcctgtcgac ggtgcccggc gtggcgatct tcaccacgaa
    33001 gtcgtaggag ccactgctga ccagccggaa ggagttggtc ccgtcctggg tccagccgcg
    33061 gcggtcggcg agcacctcgg atatctcggc ggcggcggcg ctcggccgga cgtcgatgcc
    33121 cttctcgacc aggaccttgt agcggcgcac ccggctgccg gtgcccacgg tcgtgccgtc
    33181 ggcccgggcg gtgacgaagg tgccgggacc ggtcgccggg atggcgatgg tggtggcgga
    33241 gggggaggac gagggcgacg ccgagggcga cgcggaggcc ttcggggacg gtgacgccga
    33301 gggggagggg gaagccgaag gcgtccgggt cgtggcgtcc agcgcgtccg tgacgtcggc
    33361 cacctggtcg tccgtcaccg gcggccgggt ctcccgccag tacgcgacgg ccgcccccgc
    33421 ggtgagcagg accgccccga gggcgaggca ggccaggacc gctcgggcgg gtccgcggcg
    33481 gctgcgcctg cgggcgcggg acctgtgtcc ggaaccgtcc ggcccggttc ttcggtcggc
    33541 ccggcgggcg gtggatcggc ccacggtgtg cgtcctctct gctggtcggc ggggctggcc
    33601 cggtaggccc ggcacagcgg actgcggtgc cgtcgtgccc cgatgatcca agcggacgga
    33661 cgtgcgaaaa catcgcggtt tccgaagtgt cccttctcac gcggacattc ggtccgtgcg
    33721 ggcaaccgtt cgatgccccg gaacgtcttc gtcggggtca cccggaggag atccgggcga
    33781 ccccgacgca tgcggggacg gagtgccgtc agccggcggg ggtccgctcc cagcggtaga
    33841 agcagcgcgc catcgcgtcc ttcggaccgc gccacgtcgc cgggtcgtac gccgagacgt
    33901 acggttcgag ccgctcgctg acctggcgga actccgggtg cccggtcagc ctgccgatgg
    33961 tgggggccgg gtcctcgtcg ctctcgatga ggtgcaggta cacgccgtca ccgaactcga
    34021 acaggctgcg ccggttgacg cccaccaggt gcggcagctc gccgctgtcg gactccgcga
    34081 acaccttcgc gatgtccggt gccgcgccgg gtgccatccg ggcgacgatc agtgtgtggt
    34141 gcatgagggt gctgcccttc gccgatgtcc gtacgggtca gtcggcgagc accgacgcgg
    34201 tccgccgctc gcccgccgcc tgctcgatcc ggtcccggat cagcgccatc tgcgtacgcg
    34261 agttgcggtt gatgttgtcc gtcatccagg cgtcgtccac gggcgcgtcc ggcttcatcg
    34321 cgaagtcctg cgtccagcgc atgacggtgc cctcggcggt ctccgcgtac tcccagacga
    34381 tgttcatgta ctggaagggc ccggtctcga cccgctgggc gcggacggtg cgggtgacgg
    34441 ggtcggcgac ccgctcggag acccagctcc acaccttgcc gtcggcgtcc gggtgcatcg
    34501 tgagccggaa ggtgaccttg tcgtcgtcgc gcccgagcac ctccacggag gcgtactcgc
    34561 tgaacaggcc gggccacttc tcgatgtcgt tggtcatgtt ccagaccagc tccatcgggg
    34621 cggcgatggt gatctcgttg tcggtgtgcc ctgccatgtc acactcccgt cttgagggcg
    34681 ccgttgacca gcgcgaggaa atccgcgggc gtcttgcagc gctcggcctg ctcgggcagg
    34741 cccagtccgt accgcttctc cagctcggcc acgatgccca gcaggccgag ggagtccagg
    34801 ccgaaggtgt cgaaaccgtc gtcggcctgc tgccggaggg tgaccgggtc gacgtgcacg
    34861 ccggcggtgc gcttcatcag cgccgacagc tcctcgacgg tcacctggta gtccagctgc
    34921 tgatcggtca tgggtgtcct ccttgtctcg ggttggccgg ccacgggcac cgcccgtggc
    34981 cgttggtcgt cgttcggccg tcagcggccc tcgggcggta ccgcaccccg gcgcaggacg
    35041 agcgccgagt tcgaccccat gaggccgcgc gccaggacca gggcggtgcg cggctcggcg
    35101 gggcgggccc ggccggtcac caggtccagg tcgtggcaca cgtccagcac gtgcggggtc
    35161 ggcgggatca gcccgtgctc catcgccagc accgccgtcg ccacgtccag caccggcgcc
    35221 gcgcagtacg cccgcccggt cccggtcttg ggcgcggtga ccggcacccg cgcggcgtgc
    35281 gggcccagcg cgtcggccag cgccagcgcc tcggcccggt cggcctccgg gaccccgagg
    35341 gcgtccgcga agaccacgtc gacctcctcg ggccggcagc ccgcctcggc cagggcgccc
    35401 tggatcgcgc gggccagccc ctcccgggac tcggcccagc ggccggcccc ggtgaaggtc
    35461 gccgcgtgcc cggccaccgt cgcccgtacg tccgccccgc gctcccgggc cgccgcctcc
    35521 tcctccacga cgagcacggc accgccctcg gccggggcga aaccgcaggc cgcctcggtg
    35581 aacgggcggt aggcgcggtc gggttcggtg gcccggctca gctcggggta gcccagctgg
    35641 cagacgatcg agtacggggc cagcggcgcc tccgttgcgc cgcagaccac cgtgtcggtg
    35701 ccgttccgca cggccagcgc cgcgtgcgcc agggcgtcca ggccgcccgc ctcgtcggcg
    35761 gccacgaccc cgcaggggcc cttgaagtcg ttgcgtatgg agacctgacc ggtgctggcc
    35821 gcgtagaacc aggcgatcga ctggtacggg ccgacgtggc gcgagccgtg cccccacagg
    35881 ttctgcagct cccgctgccc gaactcgccg ccgcccgaac ccgccgcggt gaccacgccg
    35941 accgagtagg gcgagtcgac gtcggcccgg ccgaaccggg cgtcggccag cgcgtgctgg
    36001 gtcgcggaca gcgcgaagtg cgtgaaccgg tcggtctgga cgaggaagcg gtcctcgacc
    36061 gtctcggccg cgtcgaagcc gtgcacctcg cccgcgaccc gcagcggcag gtgcgcgcag
    36121 ccctcccggg tgacggggcc gagactgctg gtgccgtcgg cgaccgcctt ccagtgcgcc
    36181 tcgacgccgg tgccgtgcgg cgacaacacg ccgagtccgg tgacgaccgc tcgccggctc
    36241 ccaccgccgg tgccggtccg ttgtggtccg ctcatcgcag ccctccttca ctgccgctca
    36301 gtacgaccgc ggactggaag ccgccgaagc cgctgcccac cgacagcacg tgccgcagcg
    36361 tccgctcccg tgcctcgcgc ggcacgtagt ccaggtcgca ctcggggtcg ggggtcgtgt
    36421 agttggcggt gggcggcacc acctggtggg ccatcgccag gacgcacgcg gccagttcga
    36481 tggagccgat cgcgccgagc gagtggccca ccatggactt gatggagctc atcggcgtcg
    36541 cgtaggcgtg ctcgcccagc gagcgtttga cggccgcggt ctcgtgccgg tcgttctgct
    36601 gggtgccgga gccgtgcgcg ttgacgtagt cgatcgccga cccgtcgagt tccgccatgt
    36661 ccagcgccgt gtcgatggcc cgcgccatct ccaggccctc cttggtgagc ccggtcatgt
    36721 ggtaggcgtt gccgaaggtg gcgtagccgg agacctcgca gtacacgtcc gcgccccggg
    36781 cccgggcgtg ctccaggtcc tccaggacca gcaccgccgc gccctcgccc atcacgaagc
    36841 cgttgcggtc cgcgtcgaag ggccgggagg cgtgcgcggg gtcgtcgttg ttcggcgagg
    36901 tcgccttgat ggcgtcgaag caggccatgg tgatcggcga tatcggcgag tccgccgcgc
    36961 ccgccaggca cacgtcgacg cgtccctcgg cgaccgcgtg gtaggcgtac ccgacggcgt
    37021 cgaggccgga cgtgcacccg gtggagacgg tctgcaccgg cccgcgcacc ccgaactcct
    37081 cggcgaccgc ggaggagagg gtggccgggg tgaacgcgcg ctccaggtgc ggttcggagc
    37141 gccggtcgtc gacgtcccag cgcgagccgc gctcgctgac caggacgtag tcgtgctcca
    37201 gccgggtggt gccgccgacc gccgtgccga gcgtggcacc ggcccgccag gggtcctcgc
    37261 ggttcatgtc gaggttcgcg tcccggaccg cctccgaggc ggccaccagc gcgaactgca
    37321 cgtacctgtc gcagcgctgg gcggtggcga ggccgagccc gtggtcggac ggctcgaagt
    37381 cgcactcggc ggcgatctgc gagcgcagcc cggacgggtc gaacagggag atgcggcgcg
    37441 tcgccgtacg gccctcggac agcagcctcc agaactgggg cgtgccgatc ccgcccgggg
    37501 cgacgacgcc tatgcccgtg acggcgaccc ggcgccgggt catgacacca cctcggccgc
    37561 gggggcgggc cgctcgtgcc cggccgcgtg gcccgcgtgc gcaccgtcgc aggggagcgc
    37621 gttgccctcc gcgtcctccg tgtcgacgtg gcccagctcc ggacgcgggg ccagcggccc
    37681 caggtggaac acgagccgcg cctcgacgtc ccccgcgttg cggaagcggt ggcgcatgtc
    37741 ctgcgggatc agcagcccct gcccggtgcc gagcgagtgc ggcaccccgt ccaggtccac
    37801 ctcgagggcg ccctccgtga cgtacacgaa ctcctcggag tacgggtggt agtgctcggc
    37861 gatgcggtcg ccgggctgca cgatggccac gcccatgaag ccgctggtcg acccggcggt
    37921 ggtgggcgtg aggagggcgc ggaggtctcc gccgcggcgg cggttcgggg cgatgtcgcc
    37981 gagggagacg atgcgtacct gctggtctgt catgtcgttc actccggggt gacgggagga
    38041 aggaggggag gagaagaagg agaagcgggg gaagcggggg agcaggggcg gcgcggaagg
    38101 ccgcgcggcc cggcgggcac gccgtcgggc ccggccggcc gcgcggtcgg gggcgtgctt
    38161 caggaaccgg ccgaacgccg gtcggtcagg ggcgtcatac ggatccggcg cagcagccgg
    38221 gacagcgtcg ccgcctcggc cggcgacccg tcgacgccga cggcggcggc gtccagcagc
    38281 cgctcggcat ccgcggcgcc ccggccgtgc aggccgagga cctcggcggg cgcgtcctcg
    38341 gggtcgccgt ccacgtcgac gagccgtacg acgaggtcgt cgcggtggaa gacggtggcc
    38401 gccagcaccg ggccgtccgg gttccgggcg gcggccgcgt cctgacgggc cagcagccgg
    38461 gccaggtccg gaccggcgcc gtcgcgtacc gggtagagca gcgcgagccg ttcccggcgc
    38521 gcgcccgacc ggtcggggta cgtcgcgtgg tggacggccg gcatggcggc ccgggtgaag
    38581 aagcgccggg cggactgcgg gtcgccgagg tcccggtcct gctccagata cgggttcagc
    38641 gcctcctcga cggcccgtac cccgggctgc cgggcgacgt ggcgcaacgc ggtctgcagg
    38701 tcgccgcgca cctccacggc tcgcacgatc cggttgccgg acatgaagag cgaggtgcgc
    38761 agcagccgcg tggagccgtc cacgtgggcg tcgggcgaca cgtactcgga cagcagccgc
    38821 gcggtctcgg cctcggtgcc gggccgtacg gtgaaggtga gggcgtgccg tacgacgttg
    38881 tccccgatcc ggggcgcgga gcgcggctca ccgggcgccg ggcgcccccc gtcggtctcc
    38941 cgcaggacgc tgtagcgcag cgagtgggtg tcacggacgc aggtcgccag cggttcgacg
    39001 gtgtccaggt gctcgtcgct gttgacccag gccaggaagg gcgcggcgct ctcccactca
    39061 ctggtgagga gccactgggt cggattctcc agggactggc acagctggtc gctgacgtgt
    39121 ccgggaacgg cggcgacccg gtcgcggatg cgctcgtagg cgtccaggaa ctcctgctgc
    39181 attccgtcgt ggacgtccag catcaggacg acccgcacgc gggaaccgtc gaacgcggat
    39241 atcgacacgc cacccgcgtc cgtcgccacg gcgggcgacg tcgccgacgt cgctgtggtc
    39301 cgcgtcgcgt ccgtgctcgg ggcatccgtc gctacgacgg gagagaccgt catccggccc
    39361 acctcttctc cggtcatcct cgtggactgg ggcgatcgtc ggcggcgccc gccaggccgg
    39421 cggggtgcga cggtcgcgta agcacgatcg tgggccgtgc ccgcggggac cgcgaaccag
    39481 gagggttaag cgggtgaagc ctgcgccgtg gcgggccccg acgggccgta cggggcatgc
    39541 atgaaggccc cggcgcacct cggtcggacc cctctcggac ccctgacgca ctcctgacgc
    39601 atccctgacg cgcatctgaa cgcgcgtccg acgcactccc gacgcacttc cgacgcaacc
    39661 cctgacggac acctgtcgta caacggagga cgaatcatga acgaaagagc cgaccggtcc
    39721 ggcggcgccg cccccggggg cgaccggacc caccgcgtcc cggtcctggt cgtcggcggg
    39781 tccctggtgg gcctgtcgac ctcggtgttc ctgggccggc tgggcgtccg gcacaccctg
    39841 gtggagcggc acgccggcac ctccatccac ccccgcgggc gcggcaacaa cgtccgcacg
    39901 atggagatct tccgggtggc cggcaccgag ccggacatcc gcagggccgc cgccacgctg
    39961 gccgacaacc acggcatcct ccaggcgccg accctggccg gcgacgcggg ggagtggctg
    40021 ttcaagcaga tcgacccggg cggcggactg gcccgcttca gccccagctc ctggtgcctg
    40081 tgcagccaga acgacctgga gcccgaactc ctcacgcacg ccacgaacct cggcggcgac
    40141 ctgcgcttcg gcaccgaact gctctccttc gaggccgaca ccgagggcgt cacggcgatc
    40201 gtgaagagcc gggagaccgg cgagcacacc accatccgcg cggactacct ggtcgccgcc
    40261 gacggccccc gcagccccgt ccgcgaacag ctcggcatcg gccagagcgg acccggcgac
    40321 ctcttccaca acgtcagcat caccttccgc tcgcgccgtc tcgccgacgt ggtgggcgac
    40381 cgccggttca tcgtctgcta cctgacggac gagaacgccg acggagccct cctgcccgtc
    40441 gacaaccgcg agaactgggt cttccacgcc ccctggcacc ccgaacaggg cgaaaccgtc
    40501 gaggacttca ccgacgagcg ctgcgccgcc cacatccgcc gcgcgatcgg cgatcccgac
    40561 ctcgacgtcg agatcaccgg caaggccccc tggcacgccg cccagcgcgt cgcccgcagc
    40621 taccgctccg gccgcgtcct gctggccggc gactcggccc acgagatgtc ccccaccggc
    40681 gccttcggct ccaacaccgg catccaggac gcccacaacc tcgcctggaa gctggccgcg
    40741 gtcctcgagg gctgggcggg cgaggccctg ctggacacgt acgacacgga acggcgcccg
    40801 gtcgcggagg ccaccagcgc ccgcgccgcc catcgctcgg tcgagcacag ccacccgggc
    40861 ttcgcgccgc cgccggtcgc ggggggtggc ggtccgggcg cgggtactcc cggcggtgcg
    40921 ggccgtggca ccggtgggcc tggcggtcct ggcgggcctg gcggcctcgg tggtcctggc
    40981 ggtcctggcg gtaccggtgg tcctggcgga cccggtggtc ctggcggacc cgacggtcct
    41041 cggggtgcgg gtggtgcgcc tggtggcggc cccggtggcg gtcccggcgg cggcggcccg
    41101 cagcgcggga tcctcaacgt cgccctcggc taccgctacc cccggggcgc ggtcgtcggc
    41161 gccgacccgg cgaccccggt ggtcccggag ggcctcgacc tcaccggagc acccggcagc
    41221 cgggctcccc acctctgggt gcgccggggc caggaccgcc tgtccaccct ggacctctac
    41281 gaggactccc tcgtcctgct cagcgacgcc gcccagccca ccggctggca cgaggcggcc
    41341 gccggggtgg ccgccgggat gcgggtcccg ctgaagtcgt accgcgtggg cgggtccccc
    41401 ggggccgatc tgaacccgga cgacgaggag accgactggg cgcgcgccca cggggtgacc
    41461 cggggcggcg cggtcctggt ccgccccgac ggcttcgtgg cctggcgctc cccgggcccc
    41521 gcccccgacc cggagtcgat gctgcgccag gtggtgggga cggtgctggc ccgaagctga
    41581 gtggggcacg ggacacccca aacgtggacc actccccgtt tacctgctag cgtcacgctc
    41641 ggcagtgaag cggggagtgg tccccgttac gggaggggtg acggacgtgg cggacacggc
    41701 gctggtgctg ggcgggggcg gtctgaccgc gtacggatgg cagatcggtg tcctggcggg
    41761 gctggccgac gcgggggtgg acctcgcgga cgccgacgtc ctcgcgggca cgtcggcggg
    41821 ttcgctgctg gccctcgacc tggccagggg tgcggccccg gccggcctct acaaggagca
    41881 gctcgaccgt gaacgcccca tgctggacgt ggacttcacc ttcggcatga cggtcaggta
    41941 cctgtgggcc gcgctgggct cgcgcgaccc ggagacggtg gtcaggcgcc tcggccggct
    42001 ggcgctctcc gtgcgcgacg tgccgcagag cgcggtcttc gccgccatcg gcgcccaact
    42061 gcccgtgcgg gactggccgg acaggaccgt ccggatgttc gccgtcgacg cgctcaccgg
    42121 ggaaccgacc gccttcgacg ccgacagcgg ggtcgacctg ctgcacgcca tgtcggcgac
    42181 ctgcgcactg ccgcccctct tcccgccgat cagtatcggg gcgggccgct ggatggacgg
    42241 cggcgtccgc tccacgacca acgccgacct ggtcgacgac tgcgcacgcg tcgtcgtgct
    42301 ggccccgatt cccaagggcg cgggagcgag cccgagcgcg cggacccagg ccgagaccct
    42361 cgcctcgcgt ggcgcccggg tcgccctgct gacccccgac cgggcggccc gccgcgcctt
    42421 cggccgcaac gccctggacg cctcccgcat ccccggggca gcgcgggaag ggcggcgcca
    42481 gggcgcggcc cacgcgggac gcatcgggga gatctggcag ggctgagcgc ggctcagccg
    42541 gccggcgtcc cgaggggccc gaggggcccg gggaaccgcg gaatcagccc aggcgtggct
    42601 cggacaggcc ggacacctcg tcgaccaagg gctggacgcg gtaggggacg acggcgctga
    42661 gggcgatgac cgtcgtactg cgtcgcaccc ccggcacctc gagcacctgg tcgatcacct
    42721 cctgcacatg ctggttgctc gtgcccgcga tacggcacca gatgtcgccg gggcccgtca
    42781 cgacgtgcgc ctccaggatc tgcggcacgg ctcgcagccg cgcggcgatg gcctcacggg
    42841 ccggctggtc cacctcgaac gtcgtgaacg cctggaccac gtgcccgagg gcggcgacgt
    42901 ccatgtccgg cccgtaaccg gtcaccacgc cggatccggt caaccggtcg agccgcgcct
    42961 gcaaggtgcc gcgggcgacc ccgagccggc gggcgatctc caacaggccc tcacgcggac
    43021 gctcccggag cagccgcagc atccgcccgt cgagctggtc gagcccctgt cgtgccactg
    43081 catctgccga tctgccacgc gaagagcacc ccgatgccgc ttctcctgcc aaatagacaa
    43141 ccagaagatg catcagttgc ccaataggca ccccacgccc caccctgtgg gctcccgtcc
    43201 aggaggagac ccgtgaggca gcacacgcac ccgttcgtcc cctaccgccc cgaccggtac
    43261 gacgaggccg aaatgatccg gcgggggcgg gacttcgtct cgttcgtcga ccgcaggcgc
    43321 agcgtgcggt tcttcagcga cgagccggtc ccgcgcgagt gcctcgacct cgccgtcgcc
    43381 gcggccaaca ccgcaccctc cggcgcccac ttccagccgt ggaagttcgc cgtgatcggc
    43441 gacgccgcga ccaagcaccg catccgggtc gccgccgagg aggaggaacg ggtcaactac
    43501 gagggcggac gcatcccgcc cgagtggcgc gccgcgctcg cccgcctcga aacggactcc
    43561 gacaagggct tcctcgacgt cgtaccgtgg atcgtggtct gcttcgccga gaagagcacc
    43621 gcgctgccgg acggatcgct gcgcaagaac tactacgtga acgagagcgt gggcatcgcc
    43681 tgcggcctct tcatcaccgc cctgcacgcg atgggcctga gcaccctcac ccacacgccc
    43741 aacccgatgg ccttcctcac ccggatctgc gcacgccccg gcaacgaacg cccctacatc
    43801 ctcttccccg tcggctacgc ggcacccgac tgcgaggtcc cggacctggc ccgaaagccc
    43861 ctggcggagg ccatcaccga acccccgcgc tgacgccccc gaccgccgtg ggcgtcgtcg
    43921 gggcgctgtc gggcccgtcg gctcaggccc ggctcacctc ccggccagcc gccgccggcg
    43981 gaccaacagc ccaccggcca ccccggcgac ggcgaaggca cccgctccca ccccggcgac
    44041 gaccggcgtc gtgtcaactc cccgacgatc cgcacgccga catcaccgcc cccactcgcg
    44101 agtgcccggt ggagatcacc ctggcggccc tccagggccg ctggacgacg ctggtgatcc
    44161 gcgaactact gcgcggcgac cactcttaca gcgacctgcg cgccgccctg gccgccccct
    44221 cggacaaggt gaccaaggtg gccgccgacg tgatcacccg gtggtcgtcg gcgcgagcaa
    44281 gggcgagcca gccggtgacc gcgcgatcgc gcaggacggc cttggccagt cctccgccgt
    44341 cgaggacgag ggcgccgccg ggaaccgcgg gggaccggct cacgtctcct cgtccgagac
    44401 gggtccgtgc tcggcctcgg cgacactgat cagttcactg aggttgtccc gttcgatctg
    44461 acgggccgcg gccgcggcca cgtaggcgga cagcccagag ggtccactgc gggccttggc
    44521 ggcttccgcg atgtcgcgcg gcatggtgat cgagtacttg ccggtaggct cactcgagct
    44581 atccatcctc ccgaatgagc ggtgggcaac caggccggaa cgatccggac ccacgccctg
    44641 ctgtcattgc gtaggtgacg ctccatcagt gagcttcttc gatgtggcca ccgatcgggt
    44701 gacgggccgt gaagcgcaac gagcgaggcc cccgggctgt tgatcgagat gtctgacgtc
    44761 tcaatcacgt tgctcggggg cctcgttggt catgcatcct gccgcacttg acctgccgca
    44821 tgcactcgtg gagtgggcca ccatgctgat cgtcacccgt gagggcgacc ggcgctgcaa
    44881 gctccgcccg tcccagcgcg cgatggtggc actggtgtac ctgcgcgaac acaccactct
    44941 ggcgaagatt gccgccgggt tcgggatcag cgagtccacc gcccacgcct acacccgcgc
    45001 ggtcgtcgac cttctcgccg cctgtgcacc gggcctgctc aagacgctgc gcgaccacga
    45061 acccgacttc gtcctgctcg acggcactct cgccgaatgc gaccgggtcg gcgacggccg
    45121 ggccgactac tcacacaaac accgtcggca tggtgtgaac gtgcaggtcg tcaccgatcc
    45181 cggcggccgg ctgctgtggc tctcgcccgc tctgccgggc cgtacccacg acctgaccgc
    45241 agcccgcacc caccggatca tccggatctg cgagcgccag ggcgttccga tcgtggccga
    45301 tctcgcgtac cagggcgccg gcccgtggct gaccacgggc atcaaacgca agcccctgca
    45361 ggaactgacc cctaccgaca agacccgcaa ccgtgccctg gccgcagcac gcgcacccgt
    45421 cgagcgcggc gtcgcccgcc tgaaatcctg gcggatcttc cgcaggtccc gctgcagccc
    45481 caaccgcatg acgtcaatcg ccaaggccgt cctcaccctg gagttgcacc gctgaagaag
    45541 ctcagtcgat gaatggcgac cggtacttgt catgggctgc atctgacggc actcgcctgc
    45601 acatacgcga agacccggcc tcagcgtttc cgctggtgac ggggtctttg ggcacctcat
    45661 acagggtgcc cccggcagga ttcgaacctg cgcacacggc tccggaggcc gttccggcac
    45721 ctcacatctg ggcacgtcat gaggtcacag ccggccaact accttgctcc agtccacgaa
    45781 cagtccacgg tttgtcagct gcctgcagag ctagagctgg agctaacgtc tgcctgagct
    45841 gtgcgctcat gccggcgttg agcggggccg gtcactgagc ttcttcagcg ttgccgctcc
    45901 aaggtgagta cagctttggc gattgacgtc atgcggttgg ggctgcagcg ggctctgcgg
    45961 aaaatccgcc aggacttcag gcgggcaaca ccgcgttcga ccgatgcccg cgctgcggcc
    46021 agggcccggt tgacggtctt cttggtgggg gtgagttcct gcaggggcct gcgtttgatg
    46081 cccgtggtca gccacgggcc ggcgccctgg taggcaagat tagccaggat gaggacgccc
    46141 tggcgctcgc agatacggat gatgcggtgg gcgggcagcg gtcaggtcgt gagcccggcc
    46201 cggcagcgcg ggtagccaca gcagccggcc ctccggatcg gtgaccacct gcacgttcac
    46261 tccgtgccgg cggtgcttgt gggagtagtc cgcgcgtgag tcgccgaccc ggtcgcactc
    46321 ggcgagggtg ccgtccagca ggacgaagtc ggggccagtc tcgagcagga ccttcagcag
    46381 acccggcgcg cgctgggcga gtaggtggat gaccgcgctg gtgtaggcgt gggcggtgga
    46441 ctcgctgatc ccgaacccgg cagcgatctt cgccagggtg gtgtgctcgc gcaggtacac
    46501 cagtgccacc atcgcgcgct gggacgggcg gagcttgcag cgccggtcgc cctcacgggt
    46561 gacgatgagc atggtgaccc actccacgag cgcatgcggc aggtcgagtg cggcaggata
    46621 gatgatcaac gaggcccctg agcagtgtgg ttgagacgtc agacatctcg atcaactgcc
    46681 cgggggcctc gctcgttgcg cttcgcggac gtcacccgat cagtggcccg ctcgaagaag
    46741 ctcactggtc aatcctgtgc ccgcttcagg agcctgatga tgagccaact tcctgtccaa
    46801 cgggggtcgc aggcgttatc ttctcccaat gagcatgatc tacgaacctg cgaagaagac
    46861 ggttggcgac ctgctgggtg acgtagccaa gaagacatcc gtccctgatt accaacgaga
    46921 ctacagctgg acagaaagtc atgtcgacta cttttggcaa gacgtgctcg gcttcatgcg
    46981 ggagcagaat gaaaaaactc tagccgatgc agagtacttc atcggctcca tggtgcgtgt
    47041 agataaggcg gagaggtatg agctgctaga cgggcagcaa cgcctagcca cgattgtaat
    47101 cctcctatca gcaatcagag acagacttcg cccgctcaac acgaaggcct acataaagac
    47161 ccaagggcgc tggatagcgg aagaagatga ccttacgggt gaaagcaaat attcgctaac
    47221 tttgagtacg tacgaccgtg actacttcag aaggcgtatc cagaacgatc ctgttgaaac
    47281 ccttaagccg gcgacagcca gtcagacgtt gattgatgct gcgcgaagaa agttcgatgc
    47341 cgaactaact agcgaactcg acaagcaacc cgacgagaaa gggcgtgagc agtggctgct
    47401 gctgttgcgt gatgtgatta tgaatcacgt aactacagtc actgtcacat gcgcaagtga
    47461 acaagatgct gcgagcatct tcgagacatt gaatgatcgg ggactcggac tttccaccgt
    47521 agacttgctg cgaaacttcg ttcttcgtag ggccggcgaa ccagatagag acgaaatcgt
    47581 tagcatttgg gcagacgttt tgagagagtc caactcggtt gatgtcgatg agtttctacg
    47641 gcattactgg atttctcgcc atggcgacat caagtcgcag cgactttatc gcgcaattag
    47701 gaaatatatg gaggatagtg gggaatcaag ccttgagttc atgcgtgacc tcggttcggc
    47761 tcatgccgcg tacgtgcgcc tcatgcgtcc agacttcgcc aatgacgcaa ccaacgagga
    47821 gctgcagaac attgccgatc tgaaagcgaa gatgctctat ccgtttctct tgagcggcct
    47881 aactcgcgac gaagagggat tcctttctct tgtgcgtgca gggatcgttt tctatgtacg
    47941 agaagggatc gtggttaaaa gaaacagctc gcagatggag aaggtggtgt tctcggctgc
    48001 ccgtcttatg tcggaagggg gcgccacgga taaagctctc gccctgctgc ataacggcgc
    48061 atctgctgac ccagtgtttg atgcggccgt tcgcgagcta agaaacctgg acacgtctgc
    48121 agccagatac cttctccgcg agatcgagat ctcgctccga aatggtgaag agactgatgt
    48181 tgctcgccct cccaagattc acatcgagca catctatccg cagaagccaa aagcgggtga
    48241 gcgatggtcg aatcatactg actatgtcgg gaagatcggc aacctgacgc tgttggcgcg
    48301 acgcatcaat actgcaatca aaaactccga gttcgcagtc aagaggttgg aactggcaaa
    48361 gtctgagatc ttcctgacca gggaagtcgc agcgcacgga atgtgggatg ctgcggccat
    48421 tgatcagaga caggatgagc tcggcaaaaa agtaaaatcg ctttggggtt ggcctcctga
    48481 tgttatcgag gcagtgaata aatttcctac acatgtggaa gcgtgaggag tttcctgtta
    48541 cgtaggctct gactgcagcc ccggtctgct cccagctgca aaatcacaat gccggttaag
    48601 gcgatgctgg ttaaggtgcg ttggttgctc acctaacacc cggcgttccg ccatggggac
    48661 tgctgcgatc tgacacgggt ctaatgcagc ctcctcctca ccacaaatac cgaagttcgg
    48721 tcgctgagtc tccactgcgg ctccgagtgg cgtgctgatg gatacggaca tcacccaagt
    48781 cgcggcacac tgactgacgg tagcgggaca tgcgaccgaa ccttgggttc gccgactcgc
    48841 ttcttgccgc cacccctctg gatcggtctc ctgtacgatg accgccgtcc caactcctgg
    48901 gaaaattgcg ccacttccag tccacggact cgctgctggc gtagcccact gcaccctccc
    48961 caaagggagg ccgagtgatg gagagctcat gcccaaaacc gcgcacatct acgtacccag
    49021 cccttctcgc gagaaccttg agatcgggct cgaccagggc ttgtggggat ggcgccgcag
    49081 cgccctcgac cgtgccggca ctcgtcaggc agtccagtcc cttaccgaag gcgacttcct
    49141 cgtcctgggg caccgggggc ccaacagccg ggttgctccc ggcggatggg cgaatgcgac
    49201 cctgcagcgt gtcatcgtca cccaggtcag ccggccctac ttcaccgaca gcacccctgt
    49261 ctggccgggc gacgactacc ccgagcgcat cggcatcgac gtcctcgagg aagaacagaa
    49321 cgtgccgggc accgccctcg gtaccgatgc catggaagct ctgcgcctgt ccgccaacaa
    49381 gcagggggcc gcggtcctcc agcctggtat cgcagccgtc gcccagctcg ccgacgtgct
    49441 cccgcttgtt cctgtccttc cgggcgacgc gaccgtggac cacgagggca ccgacagcgc
    49501 cgtcgcccag gtactcgtcc gtcgggagca ggtcaagctc cgcaagaacc tgctcggtgg
    49561 cgccactgag gcggcctgtg ccttgtgcgg ccgtgtcctg cccacccggt ttatccgcgc
    49621 cgcccacatc aagcggcgca gcgcggccag ccgccaggag cggctgatga tggccaacat
    49681 catgccagcc tgcctcatcg gctgcgacga gctcttcgag cacggctacc tgtacgtcac
    49741 cgacaacggc accatcgccg tcagcccgaa gagcaacgcc actcctgacc tggctgtcgc
    49801 ggcgaaggct ctcgaaggcc gtaccgtcgc cgactacggc ccccaccgcg cacccttcta
    49861 catctggcac cgcacccaca tcgccaactg agtgagcgca gccagttgga ccagcacgca
    49921 gacaaattca gggtgtgtgg ctcactccct acaagcgagc cacccatctt gaccagccat
    49981 attgcgcggt cacagatgtg ctcaagcgtg actgactgcc tagccgaact cgttggcagt
    50041 tcgttgtccg gccctatcgc ttcttgtcct tgccccgggt ggaggccgag gggcgccagg
    50101 cgcgcaggtg gtcgtcggtg agtccgtgtt cggcctgctt ctgctggcgg taactggcga
    50161 agaagtccgc cgggggcccg ctgtagagca tgtcgaaccc gttgtgccac tggtacaacc
    50221 acggctgcag ttccagcagg ccggcgagga acggtgtgat ctcctcggtg gtcagcgcgg
    50281 tgttggtgaa gtacgtcgcc agcgcctgcg cctgctcctt gtggtcccag ccggcccagc
    50341 cgtacagctc gggggtggcg gcgttggtct gcccgtagga gatgaaccgc tccttgggca
    50401 cgtccagctt gccgcgcgcc cgccaatagg aggggcgcag gaagtcggcc gaggcgtact
    50461 tcggcggcac ggggatggag tcccggatct tccgcttggc aggctcgtcg ggggcggcgt
    50521 cttccttgcg ctggaggtcc cagacctcct cccagtccgc gtgcttcttc agcccggagg
    50581 gcttgtagcg cagggcggac aggaacggca cgtgctcgtc agtgatcagc tcggcgacga
    50641 ccttgtgcat gtcttggcgg ggtgcgtaaa gcttggccac ggagacgaag tcctcgtcgc
    50701 gcgagagcgc gtcggtaagc cgggccaggg tgaggatcgt gggctggccg ttctcgtcga
    50761 accacaggtc acgatcctcc atgtggtcga gcagccagga gcgcagcgcc ttttcctgaa
    50821 gcgcgtccca accctcggtg gcccagcgac gcttgtactc aggccgctca accatgccga
    50881 tggcgcggtt cgactcgatc gcgtcgatcc gcttctggac gacctcccgg taggaggcgg
    50941 gccagtgagc ggggacctcc gtgttggggg tggagttgtg ccgcttgaac cactcgtcgc
    51001 tggcttcgcc cgcggctaca cggcgcgcga gaacgatttc gaaggcgcgc tcgccaaggg
    51061 caagttcggg gatgttgggg tcgtcgggat cctcggagac tcggagatct tcagagtgca
    51121 ggttgtagag ggagtagacc tgccagtcca actcctcctg gagagcgatc atgcgggcac
    51181 ggatggactc ccagcggact ttagcctcgc ggagggcgct ggcgaccggg gcggcctcaa
    51241 ctgccacggc ttcggggctg atggcgctga gttgctgggc cagcgcatca agggtggtag
    51301 caagggtggt ggggtgctca gctgggagag ggaactcctg gagcttggtg ccagtgaact
    51361 caaagaatcg ttcccagtcg tcgctggtaa agccgccacc ctctccacgg atccccttgt
    51421 cgtgactgac ctgcttcagc caaaaaccag ccgtagaact attaagtagc ccaagcagtt
    51481 gaagatgttc ctcctcactt gccccctcct gcaacttgat cactggtgca gtgcggttga
    51541 atactttccc gccccgatcc aaggaaaagt gactgtgggt agctacaaac gggaatgcga
    51601 taccaagtgg agttgagtac cgcttcggga aaaacatgct gtggtcaaac cagcggaggc
    51661 ctcgctcagt gggcgtctgg ccgaagtcca atcgcctccg cagcacagtt cgatttggcc
    51721 agagaaaccg gtattccggt agtgtgattt cacgcggatt cccgcgcgag tcataaggaa
    51781 agtacgttga caagcgggag ttgatcccaa agtcccgaat gccatctccg gggactacgg
    51841 gaacacagga gtcgctcaat gccaacgtct ttgcggctga cgccttcatg tagaagcaat
    51901 catccatgcc tgtgtgggtg gtgcgtccaa ttgcatcact aagcgatccg ataattttga
    51961 tggcggattt gctaagttgt tcaaccattt caagaccgcc gttagccaag atccacggct
    52021 gcttagcaaa ataacgaccg cgctccaagt cgtctaccga cacccactga cttaccgagc
    52081 ctggcttgtc gatctggtcc acgattgcat tccacacaag accgtccttg ccgttcgccg
    52141 gcgcggcagg ctcgccctgg atgcttcgca cagtgcgaat cgtcgacaaa cgctgactac
    52201 ctttgcaacg tttccctacc aggataacgg ttggcgtccc gtgccccgga atataagcgc
    52261 ccgatgtgtc gattacctct gtcagctcga cacggtcccg gaagtacctc tcgattagct
    52321 tcgtaccaaa ctcacgcttc atgaaagaat tcgccgtgat ctggccgacc atgccatacg
    52381 cgcgcccttc atcgcccccc cgcttggcca gttcgaagaa ccgctgcgca aatggaactg
    52441 acagtgcgta tgtaccaccg caggcgtcat acagctcccg atacagctcg ttcagtttct
    52501 tgtccttgac cgtaatgtat ggcggattcc ctaccactac gtgatagcgt ccttgctgca
    52561 aaattccggg gtgctcgtgg acgtcttccg tggcgtaggt aaacgaggcc agtggatcgt
    52621 aacccccgtc ctcgtctccg cccagcgtca actccaattg ccgagcctta atgagcgagt
    52681 cgcccaccgc cagatgaatc ggccactcgt atttcgcagc ctcagccagg gtccggaccc
    52741 cactcgccgc aatggccgcc accagcagcc ggaaccgggc aatggccacc gcgaacgggt
    52801 taatgtccac cccgtgaatc gagtgcagcg cagcccgcac tcgctcatgc acgtcccgcc
    52861 ccggctgtcc ctccgcccaa agtcgcacca gtcgccggaa cgcgcccaac acgaagtgcc
    52921 ccgacccgca cgtggggtcg atcatcttca gttcctcgta gccgaactcc cgcaccgccg
    52981 ggttcatcgt ccggtcgagg atgaactcct ctacgaactc cggcgtctgg agcagcgcat
    53041 aggtcttccg ggcagcctcg ctcaggtcct ggtacaggtc gcccaggaac cgggtgtccc
    53101 agccttccgt gccgtcctcg ttcagcgggt cggtgaagtc gtggacgagg acgcccgcct
    53161 cgtcgcgctg acgccagaac tcgaccagtt cgcgtgcgcc gtcgtgcgag agcgggatct
    53221 ggtacagcgg gttatgccgc ttgtcgaaga ggaggcggcc ggcctggccc tggcccagtt
    53281 cgtcgaacgc cttctccagc cacccccgat acgtcgggtc gtcgtccgac tccacgtacg
    53341 cgtcgtaccg cgcctccgcc agctcgcgcc ggtcgccgtc cggccccgtc aggtacggct
    53401 cggggatcag ccggttgtcc tcgcagaacc gcacgaagac agtgcccagc acccacgcca
    53461 ccgcgacctg ggtgacccgc tcgtccagcc acgagttcca cgtcgccgcc gtacgcccga
    53521 gcttgcgcgc ctggtcgtat tcggtccgca gccgcgcgcc ggcctcaccg agcggtttca
    53581 cctgcttgcc caggtcggcc tcgaccgcct tgacctgctg cttcaggtgg tccaacagag
    53641 ccttgcggtc gatcacgacg cccctcctta gttacttcac aagagttctg catgttactg
    53701 ctcgcctcag agtgacttgt tgcggaagga ctccggcaaa gtcggtgtag gcacgggagc
    53761 tggcagactc aggcttccgt gctcgcagtc acgtctaagc tcctgtggcg aaccataggc
    53821 gaggtacgtt tgcgaagaag gtggcgtggg caagatccgc caactaggat tgtgatcctt
    53881 gtttcgaaac ccgggggggt ttgtgcgagt ttctgaatac tacggcatcg ggcgcagcca
    53941 gggggctctc gattttgtgg acgtagacat aactgacgat gttcctgtct atattgaccc
    54001 cggcatgatt aggcatctcc ctgacgattg gggaaaggaa tgcctcctca tgctgaccac
    54061 gtttttcgac agcgttttgg atgcagtaag gaagaatgat aaaaagcgag ccaggtatct
    54121 tctcggtcat cttggtgagc ctaatgaaac acatctaggc ttttccgctg ggcggagcgc
    54181 tggacgcgga ttcggtaaac agatgggcgt cacgctcgcg gagaaattgg cagccagtca
    54241 agccgcgcag acaggtttga ttgaagatct agaggacaca gcttttttca tcgagaaagt
    54301 cgggaaggat atcgtctctg acattacgac gaacatcatc cgtggtccgc taatcgcgta
    54361 cacgcagcag atggcgacgg tcttcggtat ccccatggag gagggggtag ccagtggagc
    54421 ggcctggaac cctcattctc aggattggga gcatggctat gtacgccttc ccattgcggg
    54481 agatcgtaag ttgctcctcg tcccaaaggt gatcgtgcgt cgcgacctgc acatgtctcg
    54541 gtcggagtac taccggaatc acctggtccc tgcgctacag agcgaagagc tggacaagcc
    54601 gagcagccgc ctagtgcgca ctctcaagga cggaagcagg agggtctggg taggggacat
    54661 taaagcgcac tacggcagca cgaaacccga cgtgacgcgc gaatcgctgc tccgcccaga
    54721 catctacgct aattacaggg aaataaagcg gaagtccgca ccacccccga tttcccatgg
    54781 ggaactcagc gagatcagca atactccgct gccagattac gagaaactac tgactgatgt
    54841 tctgcagact ccggcaggca aggattcggc tggagagtac catcggcgca tcgaggcgct
    54901 actaagcgcc gtattctatc cttcgctcgt gatgcccgag ctcgaagagg agcttcacgc
    54961 tggccgtaag cgcgtggaca tctcctacac caacgtcgcc cagagtggtt tcttcgcctt
    55021 cctcggaaag cataagatca aatccaccta tgttatggtt gaatgcaaga attatggcaa
    55081 ggaagtcgga aacccagagc tggatcagct gtcctctcgc ttttcacctc tacgaggaca
    55141 gttcggaatt cttgcctgcc gatccttcga agataaggat aggttcctca agcgatgcag
    55201 agacacagcc ctggactatc gcggatttgt cattgcgctg gatgatgacg atctccgtga
    55261 actggtcgcc gacgtcttgg aggcagtcaa ctggatacct gccgatccgc ccccggctga
    55321 gccggaagtg caaccgcggg tggaaaacta tccccttcta tttcgccgat tcaaggctct
    55381 ggtgaattag taaggacggc gagcgctccc gagtcgaagg acgctcaagc tgatcatgag
    55441 aagtcggtga ccttccggcc tggtggagga actgcttact ggcgccaacg ttcacggtgc
    55501 cttcgaacgc actcgatgtt tactttgtgt ttgggatgcg tccggagggg tcctacgagt
    55561 tggccgttct tcgagacgat caggtcgtct gacaggacga tggcgccggc atcgagcatc
    55621 acgtgacagt tcgggcagag acacagcatg ttgtccgtac ggtccgggcc gttgtggggg
    55681 cgccccagag cctgaatatg ggcgccttcg ctatagaaac cgccagggac ttcgatgtgg
    55741 atgccgcacg tctgacactg gtcctggtgc catgccttga cagtgtccgc aatcgcactg
    55801 ctgcgcacga tccgctgcac catggatgtg acgcgttccg gttgctcggt cccagacgct
    55861 gcgacggggt cttgcttagc gcagtccgtc ggctcagcaa agagggctcg taccttggtg
    55921 atcttaggcg taggagtttc ctcgtacgcc tccatgcgga actgccagat caaaaacccg
    55981 tcgatgccga gcttgctggt atagctcgca acccgataca ggccgtcgta ccggtatccg
    56041 ttggaaggag cgaaggggga accgctctgg ctgccgcgga tcacacgcac gggcaacccg
    56101 cgcagatagc ttgtgacgag ggctgcgttg cccgagtcat caagagactg gtcgctgacc
    56161 tggttgccag cactatcccg tcccccgtgg ccggtgtaaa tgatcacatc gccgtagtcc
    56221 tcgtcgtcct tgtatccgcc ggataccacg atggactctg ccccagtcgc cttcgtaccg
    56281 cagatgcctg cctggagggg gcgatggacc ccggcttcgt gggcaagacg acggctgttg
    56341 tacggctgac ctgctgctac accagggatc tcaccaatca tggacacagc ttgtcaggca
    56401 gtactgacac gccgacaccc tgttttacgg ggaggtcgtg cgcctcccac ctcaacccac
    56461 cactctccct agctcccatc ccgtccgccg tcgacccaca caccgtggag cagacgtggt
    56521 tcctggcgtc caggtggagc gcactactgt acgaacgacc tggacgccag gggccgcgtc
    56581 tgctcggctc tgcctgggtc gatggcggac gggatgggag ctccccgcgc atgccactac
    56641 ggacccgcag tcggaagcgg cgctctttcc atcccggtgc cggccgatcc cccgccggag
    56701 gcatcatctt gtgcctgcgg atgacgtccc gtccttgccc gcatgcacgc agcgcgccgc
    56761 cgggcggggc cgccgctggc gaagacaggg cggcggcccc gccggcaagg cggggcgcgc
    56821 ccgcgccgtg cgcgggcctt gatgaagtag ggaaagtctt accgcgctgg tctacgcccc
    56881 tcgatcgtgg cctgtcggct caccgctgga ctcggctacc gttccatcca tgccttctgc
    56941 actggacacg ccccagggag cggcggaact cgctgagtcc ctgcttcctc cgctcgggaa
    57001 tcgctggctg catactcagg ccgtggctgc tcgggctcgc gaggtttccg cggctgtgtc
    57061 cgaggctgac cgggatcttc tcgttgctgc tgcgtggctg catgacatcg gctacgcgcc
    57121 cggactgcgt gacaccgggt tccatcccct cgacggtgct cggcaccttg aatcgctggg
    57181 agcgccggcg cgcttggtac gcctggtcgc ccatcactcc ggggccgtgt acgaggcgga
    57241 acagcgcggg ctctcgacag aacttgccgt ctacgagcgg gaagactccc cggtcctgga
    57301 cgctctgatc ttcgctgaca tgacgaccgg ccccgccgga cagtccttcg acttcgatac
    57361 ccggattgac gagatcttgg tccgctacga gccgggcagt gaggtgcaca acgcgatcag
    57421 caaggcgcgg ccgtaccttc agggcgctgt cgagcggacc cgcgaccgca tggcgcatca
    57481 gccgatgtag ggctctgccc ggtcggtcag gccgtgctcg atccgcatgc gcatcgacgg
    57541 gtggatgttc agctcgtcca gcttgctcgg atcgacgaag gccacttcct tgctctcgct
    57601 gctcgtccgc agctcgccgc cggtgatgcg ggcgtgatag cagatggaga actgctggcg
    57661 gacctcgccg tcgtcgtacg ccatgacgtg cccggggttg gtgtagatgc cgacgaggcc
    57721 ggtcacctcc acgtcgaagc cggtctcttc cttcgtctca cggaccgctg cgtcgggcgc
    57781 tgactcgccc aggtcgatgc cgcctccggg cagggcccag aggtcgttgt cggtcttgtg
    57841 gatcagcagg acctctccag cctcgttgcg ggctacggcg gtcacggagg ggacgaggct
    57901 gttcgccttc ggagcgttgg ggtcgttgaa gtagtcgaca cgggccatgg gttcagcgtc
    57961 gcacgtccgg ggcctgttat gcctcccggc ctcgctccca cgcgtagtcg aagctccgca
    58021 tgtagtgccg gaaggtccgc gcgccgggga ggtaccgaaa gtgcattacc gggttctggc
    58081 cggcgggggc tccgaggacg tgcgggttca cgagaacgtc ctcgtcgaac cgatagatcg
    58141 agttgtagag gatcgtgtcg tgcaggcgga cttcgacgcc gagtgtcgac atggcgggtt
    58201 cgaggtagcg gcgggtgatc cgcgcgcgtg cggccaggtc gccgccgatg ccctcttctt
    58261 cgccacgctg acggaccgct tcggagtcgg ggtcgccgag caggatgcgg atctgggcgc
    58321 cggccttcgc cttctcggcc agctggtcgg gcaggtccgg atgactgtcg aagaggaaca
    58381 aaccggcgta cacgaggatg tcgacctggt ccgtcgcctt ctcgatcagg gatgaccaga
    58441 gcggagcggg caccgcgcca cggtgcgggt agtacgtgat cagctcggac gtgctggcct
    58501 tctccgcctg cttctctacc gacggccaga gatagacctc gtcgactccg aggaagctcg
    58561 ctgccttcca gcggtgcccg cggtgtgggg tgcgactggt ggtgatccac cgttcgacgc
    58621 tcttggggtc cacgccgatg tgctcggcaa cggactggat cgtctcgcct ttcgctgaaa
    58681 tcgccgcgcg cagacgctcg ttcgccatgt cgtgtccttc gctgggacca ccggggacgt
    58741 tttgacggta gctcagacgt ccctaaacgt ccatacgggc ggtgatgcgt ccacaccctt
    58801 ccgcggtctc ctgatctcac cgacgggatg tcggtcaaca ccccgataca tcaggagacg
    58861 agacgatgcg tcagatcccc gtggacacct cgaacgcgac cgtgatggtt gccaaggctc
    58921 cgcagcccaa ggtgaaggac cgccgtaccg gtgagatcgc caccgacaag gacggcgtca
    58981 ccctgatggt cgtggaggtc atgttctcca cgcccgacga ggtcgagatt ctcaagctca
    59041 ccgttccgca gcccggcgtc tccgaggacc tgaccatggg caccccggtg gcgctgaccg
    59101 gtctggtcgc ctcggcgtgg gagaacgagt tcaacggcca gaagaagcac ggcatcgcct
    59161 tccgcgcggt cgcggtgacc tcgctcgccg ccggcgcctc gtcctcgaag gcggcctgag
    59221 ccatgacgtg gctgatcgtc gccctggtgc tggtcgtcgc tgctgcgggt ctcctgcggt
    59281 ggcggcgccc cgcctggtac tggctgacct tcggggtcac cctcgccgcg ctgcgggtcc
    59341 tggtccgcta cggctcggtc atggacgcct gcggcctcac cgtcccggcc ccccgctggc
    59401 gcctgacctt ggcccggatg accaaccggc cggttcccgg tccgcgggcc ccgcgcatcc
    59461 tgcggttccg cgtcacccgc accggtctgg tgctgcggct gaagctccgg cccggtcagg
    59521 acgctttcga cgtggccgcg tcgtgtgacc ggctgcggca ctcgttcgcc atgtacggcg
    59581 tcacctcgcg tgagctgcgc tcgggtgtgg tggagctgcg gatgaccggc tacgacgtgc
    59641 tcaagcgcgt gcagatgccc gccctggccg agactcggcc gatgcgggtg ccggtcgcct
    59701 tgcgcgagga cggggccgtg cactatcgcg actaccgtgc cgtgccgcac gggctggtca
    59761 tcggtgccac ggagtccggc aagtcggtct atcagcgcaa cctcgtcgcc gcgctcgcgc
    59821 cgcagcgggt cgcgctggtg gggatcgact gcaagcaggg ggtggagctg ttcccgctgg
    59881 cccgccggtt ctccgcgctg gccgacaacc ccgacaccgc cgctgaactc ctcgacgccc
    59941 tggtgtctca catgcaggac gtctaccagc tgatccgggc cgagcagcgg atcaccgcgg
    60001 atgtgccgga tgcggagatc gctgccgaca tctgggacct gcccgagaac ctgcgcccgg
    60061 tgccgatcgt ggtcctggtc gacgaggtcg ccgaactcgc cctcttcgcc accaaggacg
    60121 acgagaagcg ccgcgaccgg atcatcaccg ccctggcccg gctcgcccag ctcggccgcg
    60181 ctgccggcat ctacctcgaa atctgtgggc agcgcttcgg ctccgagctc ggcaagggca
    60241 tcaccatgct tcgcgcccag ctcaccggcc gcaccgccca ccgcgtcaac gacgaagcca
    60301 gcgcgaacat ggccttcggc gacatcgccc cggacgccgt gctggccgcg atctcgatcc
    60361 ccaccgacac cccgggcgtc gccatcaccg gcgactcggc cggcggctgg gcccgcatcc
    60421 gcgccccgca caccacgctg cgccaggccg tgaacgtctg caaccggcac gccgacctga
    60481 ccccggacct gcccgctctt gcgccgttcc ggcccgccct cggcaccctc gccccggtcc
    60541 cggccccggc tgtcgagtcc gccccggccg ccgcctgatc ccgcccggga ggttccccat
    60601 ggctaccgcg aagaagccca ccacccgccg caagatcacg cccccggcgc cggagcccgc
    60661 gctgtgcccg gactgcgacg gcaagggcga gacccgcgaa accgtccgcg tcggcgcccg
    60721 caagatgcgc gtcaccgacg accaccagac cgccctgtgc ctgacctgct ggggcaccgg
    60781 ccacgccacc gactgacccc ggaaaggagg acacgcgatg cgcaccgttc ttcgcccgga
    60841 cgccgtgctc gtacaggccg tgatcgccgg tgccctgtcc ttcgcccacc tgcacgacct
    60901 cgccgccgcc gcgggacagg acggctggaa agcctgggcc taccccatct cggtggacct
    60961 gctcttcgtc gccgcctggc gccgcctgcg caccgacgga ccgtcccggc tgtcctggtg
    61021 ttggttcctg atcgccctgg ccgcctcgct cggcgccaac atcgccaccg ccggactcct
    61081 cgacctcagc gacgtcccgg cctggctgcg catcctcgtc gccggatggc ccgccctagc
    61141 cttcctcggc ggcaccctcc tcgcccactc accaaccggc cacgccccgg acccggaccc
    61201 ggcgcctgaa gtcgagcgcg aaccggagcc cgtgcccgaa tcagacccgg aacctgcggc
    61261 cgtcccggca ccccaggaaa ccccggctct gccggtcgcc gaaccggccc cggttccggc
    61321 ctcgccgccg gcggttccgg tcccggccgc gctggtcgac cacgcccgca aggtcgccgc
    61381 cgaccacgaa caccgcaccg gctcccggat cgacaccgac accctgcgcg cccggctcgg
    61441 cgtcccgccg cacctggccg acgccatcgc cgcccagctc acctgacccg aaaggagaac
    61501 cctcgtcatg cctgcccgtg acttcttcca ctccgtgatg cgcatcggcc cggtgcagat
    61561 cggcacccac cgcgaccggc acggccagac caagcacgcc gccgtgtgca gcaacgacgg
    61621 ctgcggctgg tccgccgact acaccagcca gtccgccgcc cagctcgccg cccgcaccca
    61681 ccgctgcaag atccgctagg aggccacccg tggacgtccc gctctggttc gccctgctct
    61741 gcgtcggagt cctcggcgtc aagctcatcc gcccgccctg gtggctcatc gccgtactcc
    61801 tcctgggcgg ctacctcctc gccgacagcc tcctggcccc ggtcatcgac accgccgtca
    61861 agtaaggaga tccgcccatg ctccggccca agctcccgac catgccccag cccaccagca
    61921 ccgtcacccc gcccgccgtc atcgaaccga ccaccatcac cccgggcacc ccgccgccga
    61981 cccccaccgc tccggctccg gccccggtgt cggcccggcc cacgatgcag ctcaccccag
    62041 gcaccgcgct cgccctcgtc ggcggcggca ccgcggtcgt cctggtcgtc ggcgccgtcc
    62101 tggtctccat gctcctggcc gttgccatca ccgccgcctc ggtcgccgtc tgcgccgttg
    62161 tcctgcgctc gctgctcgcc tccgacgcca agcgtcgctg accggtcccg ggggcgacgc
    62221 acaagccgcc agcacgccgc cacctccggg accgggctcc gccaaccgct ctcaccgaag
    62281 gggaacgctc atggatctgc agatagccgc cgccctggtg ccgttactgg gctgggccgt
    62341 gcacgggagc atcctcacgc accgcctcgt ctccgcccgc cgcgacccgc tgaccggcct
    62401 gcacacccgc gccggatgga ccgcccgcgc cgaacactgc atccgccgac acccggacgc
    62461 cgccgtcctc ctgctcgacc tcgaccactt caagaccctc aacgacaccc acggccacgc
    62521 cgccggagac gccgccctcg tcgccaccgc cgaccggctg cgcacctggt gcggacgcca
    62581 cggcaccgcc ggccgtctgg gcggggacga gttcgtggcc gtcgtccagg acctgaccgc
    62641 cgccgacctg gacgcgctga tcgccgcact gcaccggccg ctgcactacg ccgggaggtc
    62701 gctgccgctg gccgcctcgg tcggcgtctg ccgcctcgcc gagctgccga tgccgctgct
    62761 gaccgatgca ctcgccgccg ccgatgcggc catgtacgcg gccaagggcc gcagccgccg
    62821 gggctcgcgc ctctctcgct gaccggccgc cgggtggcgc acaagccgcc aagcacgccg
    62881 ccacccgggg ccgttccttc caaccgcaat cgaaaggaac caccatcatg gcccagcaca
    62941 ccccgcccgc gccgcgaatc tgcccggcct gcgacggctt cgccaccgtc gccgtcaccc
    63001 tcggcggccg agacccccgc ggccacctgc gcaccctcac caccgactgc ccggcctgcc
    63061 acggcaccgg caccgccccc gcccaccgcg tccgggaggg cgcccgtgcc tgacacgctg
    63121 ctcgacccga caaccctcgg cgacctgctg agggtggctt cggcccccga ctacacccgc
    63181 tgggaagacc agatccgccg caccggcggc tgcgccgacc ccatccacct gaccggctgg
    63241 acgctccaca aggacaagac caccggcgcc accctgcacc actacaccac cgccgacgaa
    63301 cccggcggac gcctccgcct cgcctgcggc aaccgccgcg cctcccgctg ccccgcctgc
    63361 gcctggacct acgccggcga cacctaccac ctcatccgcg ccggactcgc cggtgacgac
    63421 cgccgcgaca tccccgccac cgtccgcgac cacccccgcg tcttcgccac cctcaccgcc
    63481 ccgtccttcg gcccggtcca caaccggccc gaccgcggca cctgccgctg cggcacccac
    63541 cacgccccgg acgctcccga gctgggcacc gccctcgacc cggacaccta cgactacgcg
    63601 ggcgccgtcc tgttcaacaa ccacgccgga cagctctggc agcgcttcac caaccgcctc
    63661 cgccgggagg tcgccgcccg cgctggcctc acgcaacgcg aactcaagga gtgcgcccgg
    63721 ctgtcgtacg gcaaggtcgc cgagttccag aaacgcggcg ccgtgcactt ccacgccgtg
    63781 atccgcctcg acggacccga cggccccgac accccgccgc ccgtctgggc caccgtggac
    63841 ctgctcaccg acgcgatccg cgccgccgcc ggccactcct acacctcggt gtccgtcccg
    63901 gccgccgacg gccaaccggc ccggaccttc cgctggggca cccagctcga cgtccgcccg
    63961 gtcaaggcgt tcggcgacgg ctccgacatc accgaacagg ccgtcgcctc ctacgtcgcc
    64021 aagtacgcca ccaaagccgc cgagaacacc ggcaccctcg accgccgcat cggcgaactc
    64081 gccgaactcg accgccacgg cgtccccgac cacacccgcc gcctcatcga agcctgcaag
    64141 acgctcgact cgctctaccc cgaccgccgc ctctgggcct gggcccacat gctcggcttc
    64201 cgcggccact tcagctccaa gtcccgccgc tactccacca ccctcggcgc cctccgccag
    64261 gcccgcgccg actaccgcgc cgcacaggga cacgccgccc tcggcatcga cgacgccgag
    64321 ccggacaccg tgctcgtcct cgccgactgg cagtacgccg gccacggcca cacccccggc
    64381 gaatccgtcc tcgccgccac catcgcccga gacctccagc tcaaccgaca aaccgcccgc
    64441 gaagaactcg cagccctgga aggagcctga cgtgaaagac gagctgatga ccgtcccgca
    64501 gatcctcgat gagctcggtg gagtgtcgcg gcggacgttc taccggtggc gcgagctggg
    64561 gcaggggccg gccgccttca agcttcccaa cggggagctg cgagtttggc ggagcgactt
    64621 ccggacctgg ttgcggcagt tggaggccgc cgcgtgaagt ctctcgacgt gaaggtctgg
    64681 ggggttcgaa agaggaacac gaagaagtcg tcctatgacg tccggtggac cgtggccggg
    64741 aacgtgttct ccgaacagtt ccgcacgaag gggctggcgg atcattaccg ttccaagctc
    64801 ctccgggctg ctcatggagg cgaggagttc gacacagtca cggggctgcc tgactcgatg
    64861 gtcgaaaagg cggcctctat gagctggtac gccttcgctc tgaggtacct cgccatgaag
    64921 tggccgcacg ctgctcccaa cacgcgtaat ggcatcaacg agtcgctgac cgcggtgacc
    64981 atgaccctgc tcgacgatcg accgggtcga ccgccggagg aactgatcag gagggcgctc
    65041 cgcaactggg ctttcgtcct tcctggtccg gacgaccgcg aactgccgga tgagatcgcg
    65101 cacgccctgc actgggtgtc gaaggcttcg cgccctctcg ccgatctcgg tgacgctgcg
    65161 atcgccaggg ccgtgctgga cgcgttgaag ctgaaactgg acggcacagc ggcagccgcg
    65221 gagactgttc ggcgcaagcg ccggacgctc gtcaacgccc tgcactatgc ggtcgacctc
    65281 ggggagttca aagagaaccc gatcactggc attcgttgga agaaaccgaa ggtcgccgga
    65341 gaagtcgatc cacgggtggt ggccaaccca gagcaggcgc gttctttgct gaccgctgtg
    65401 tcgtacgtcg gtgggtacgg tcgggcccgc ggccgtcgac tggttggcct gttcgcctgc
    65461 atgtattacg gggccttccg cccggctgaa gctgtcggcc tcaccgcggc agacctgaag
    65521 ttgccggaga cgggctgggg cacggcgttg ctgaaccgga cgcgtcccag tgctggcaag
    65581 cagtggacgg actcgggaga gacccacgac gaccggggcc tgaagaatcg gccggccgaa
    65641 gaagtgcggc tcgtgccgat cccgccccag ctcgttgcca tcctcaggcg gcacctcgac
    65701 accttcggta ccgccgagga cgggcggctg ttcaccaatg agcgtggggg agtggtcggc
    65761 tcctcgacgt actaccgcgt ctggcaggag gcccgtgcgt tcgctctcct gccggccgcg
    65821 gtggcctcgc cactcgctgc ccgtccgtac gacctgcggc actcggcgtt gtccacctgg
    65881 ctcaacgccg gtgtcgaccc gaccgaggtc gccgcccgcg caggcaacag cgtggaggtc
    65941 ttgctgagcc ggtacgcaaa atgcatcgac gggcggcaag aggtcgtcaa tcgcaagatc
    66001 gaagagttgt tgcgcgagta cgagtgacac gtacgtgagc ccttagcccc cagcccgcat
    66061 ggactggggg cttcgctata tctcggccgc gtgtcgtcgg tcgttggttg ttggctgcac
    66121 ctgccgcgtc gcttttggcc tcgctggcgg actgctgccc cagaggttcc gtccggttcg
    66181 cgccctacgc ctgggctgtc ggactggcga ccctcacggt atggggcttt tagagaggga
    66241 accgcggcgg ctgagtggtg ggcagtcccg ttgccctgac tgtgggctgt tacaggaccg
    66301 ggtgccgacg cttgagcagg attgggtgct gttggagccg gacatgaatc ccctggccca
    66361 cacggtgccg gcggagcatc ggtggatcga actgtccgat ggacgggtga cggtctacga
    66421 ggtgtgcccg ccagatcagt cccagcggtg ccgcgtcgag caccgcctcg cctgcccggc
    66481 acgacccctg ccggatctgt ggccgtggtt gacctcccta cgaggggaga acgcgcggcg
    66541 agtggaacgg cagaatgatc cggagccgcc tccacccccc gaggagtggc cggacgccgg
    66601 ctgacgggcc ctccagaaac ttcgggtctg accaggggag acagtccaag atcctgtcca
    66661 cgaatagtcc acagaccccg acatacgccc gctccgagcg gcatacggct gcacatacgc
    66721 gaagaccccg gcctcagcgt ttccgctggt gacggggtct ttggacacct catgctgggt
    66781 gcccccggca ggattcgaac ctgcgcacac ggctccggag gccgttgctc tatcccctga
    66841 gctacggggg cgtgtccgtc gcgttcggtg ttgctcgcgg cgacgggtag aacactacca
    66901 gctcgcccgg ggtggtcatg aacgggtttt cgcgggtcgt gacggggccc gtgcggggcc
    66961 ctgtcacccg cggagggcgg aagtcgggaa aacccggacg cggtggccgg tccggaccta
    67021 ctctcgagtt gtgcctaggc cgtccggccg gattcttgtc gtcgacgaca acaaggtcat
    67081 ccggcagctg atcagggtca acctcgagct ggagggcttc gaggtcgtga ccgcgggcga
    67141 tggtgccgag tgtctggaag tcgtccagca ggtgcggccc gacgccgtga cgctggacgt
    67201 ggtcatgcct cggctggacg ggctcaggac cgccgcccgg ctgcgtgccg atccgcgtac
    67261 ccgggacctt ccgatcgcga tcgtcagcgc ctgtacgcag tacgaggtcg acgccgggtc
    67321 cgccgcgggg gccgacgcct ttctgtcgaa gcccttcgag cccgccgagc tggtcggtct
    67381 ggtgcggcag ttggtggagc ggaagggaag tgggtccacc gtcgtacgcg gggcgtccgg
    67441 agcgggcccc gggcagccgg gtcccggagc cggggcctcg ccgccgcggg tgcgtgggct
    67501 cgccggggag agcggggcgt ccgcgcaggc gtgaccgggg acccgggtgc attcgggtcc
    67561 ggtcctggtc ccctcgggct gccgcttcgt ccatatcccg ggaccggcgc acatcggttc
    67621 gcctccccac ccccttcctc ccatacgctt gtcccgtgac acccgtagag ctctcccgca
    67681 ccgtgctgca cgcggtgcgt cgcgccgtcg acgcggggga gctgagcgtg gccgtgccga
    67741 cgcgtgccgt ggtcgcgccg ccggggcccg gggggtgcgg ggactacgcc accggcatcg
    67801 ccctccagct ggcccgcccg gccgggcagc cgccgttccg ggtcgccgag gtgttgcggc
    67861 cctacctggt cggaacggac gggatcaccg acgtcgtcct caccgggccg gggttcctca
    67921 acatcagcct cgaccgcgcc gcctccgacg tcggtctcgt cgccgagata ctgcgccgcg
    67981 gggaccggta cgggcacgcc gaccaaccgg acggccgcgt cgtgcagctc cactgccccc
    68041 acgacctgcg tgccgtcgtc gtcgccgagg catccgcacg gctgctccgc tcccaggggg
    68101 ccctcgtccg ggtgagcgcc gaggggttcg aggacgcctg gacctccgtc ctcggggtca
    68161 ccgtcgacgc cgtcgggcac gcccccgccg agctgcccgt caacgtccgg cccgtccccg
    68221 cccacggctc cgccgacccg atgtccctcg ggcgggacgc cggacgctgg gccctgctcc
    68281 accccgcggc cggcgaccgg ccccggatcg gcgacgagca cctcgtccag cgggagggga
    68341 atcccctgtt ccgcgtgcgg tacgcccacg cccgcgcccg ggccgccgcc cggaacgccg
    68401 ccggtctcgg gttcaccgca gcccccggcc ccgtcgccga gcgcgacctc ctcgccgccc
    68461 tcgccgacca cccccgcgtc ctcgccgccg ccgcggacca ccgcgccccc gaccggctcg
    68521 cccggcacct cgtcaccgtc gccgacgccg cgctgccgtt cctgcccacc gtgctgcccc
    68581 gcggcgggga gaaaccctcg gccgcccacc gtgcccggct ggccctcgcc gaagccgtcg
    68641 gggcggtgct ggccggcggc ctggccctgc tcggcatcga cgcacccgaa cacctctgag
    68701 agagcacgga agacgccatg agccgttccg cacaccccgc cgggccccgc cacgccgacg
    68761 tcctgcccga ggggcactac accgccccgg ccgacgacct caacgccctc gatcccaagg
    68821 tctgggcccg caccgtcggg cgggacgcgg acggggtcgt caccgtcggc gggattcccg
    68881 tcacgcagct cgccgaggag tacggcaccc ccgcctacct cctcgacgag gccgacttcc
    68941 gggagcgggc gcgggcgtgg cgcaccgcgt tcggcgacga cgccgacgtc ttctacgccg
    69001 ggaaggcctt cctgtcgcgc gcggtcgtgc ggtggctgga cgaggaaggg ctcaacctcg
    69061 acgtgtgttc ggggggcgag ctcgccaccg ccctctccgc cgggatgccc gccgagcgga
    69121 tcgccttcca cggcaacaac aagtcgccgg aggagatcga gcgtgccgtc cgggccgggg
    69181 tcgggcggat cgtgctcgac tccttccagg agatcgtgcg ggtggcccac atcgcccagt
    69241 cgctcggcaa gcggcagcgg gtgcagatcc ggatcaccgt cggggtcgag gcgcacacgc
    69301 acgagttcat cgccaccgcc cacgaggacc agaagttcgg tatcccgctg gccggcgggc
    69361 aggcggcgga ggccgtgcgg cgggccctga agctggacgg gctcgaggtc atcgggatcc
    69421 actcgcacat cgggtcccag atcttcgaca tgtcggggtt cgaggtcgcc gcgcaccggg
    69481 tcgtgggact gctcaaggac atccgggacg agcacggcgt cgagctgccc gagatcgacc
    69541 tcgggggcgg gctcggcatc gcgtacacca gtgacgacga cccccgcgag ccgcacgaga
    69601 tcgccaaggc gctgaccgag atcgtgacgc gggagtgcga ggccgcccga ctcgccaccc
    69661 cccgcatctc cgtcgagccc gggcgggcca tcgtggggcc gaccgccttc accctgtacg
    69721 aggtcggcac cgtcaagccc ctcgaagggc tgcggaccta cgtctccgtc gacggcggga
    69781 tgtcggacaa catccggacc gcgctctacg acgccgagta cagcgtcgcc ctcgcctcgc
    69841 gcacctccga cgccgagccg atgctcgtgc gcgtcgtcgg caagcactgc gagagcgggg
    69901 acatcgtggt caaggacgcc ttcctgccgg gggacctggc acccggtgac ctgatcgccg
    69961 taccggcgac gggggcgtac tgccgctcca tggccagcaa ctacaaccac gcgctgcggc
    70021 cgccggtcgt cgccgtgcgg gacggtgcgg cgcgggtcgt cgtgcggcgg gagaccgagg
    70081 aggatctgct gcgtctcgac gtcgggtgag gtccgaggga gggaaagctg ggggcgggcg
    70141 aagatcttcc ggtccgcacc ccctcagaaa atgaaataaa cgtctcacga tccggacgaa
    70201 aggcagaaaa tcccgtccgg tgcgtgagac tggtccaacc gtagacggta tgaggaaacg
    70261 aggtcggatg atgcgtacgc gtccgctgaa ggtggcgctg ctgggctgtg gagtggtcgg
    70321 ctcaaaggtg gcgcgcatca tgacgacgca cgccgccgac ctcgccgccc ggatcggggc
    70381 cccggtggag ctcgcgggcg tcgccgtacg gcggcccgac aaggtgcggg aggggatcga
    70441 cccggccctc gtcaccaccg acgccaccgc gctcgtcaag cgcggggaca tcgacgtcgt
    70501 cgtcgaggtc atcgggggga tcgagcccgc gcggacgctc atcaccaccg ccttcgcgca
    70561 cggcgcctcc gtggtctccg ccaacaaggc gctcatcgcc caggacggcg ccgccctgca
    70621 cgccgccgcc gacgagcacg gcaaggacct gtactacgag gccgccgtcg ccggtgccat
    70681 cccgctgatc cggccgctgc gcgagtccct cgccggcgac aaggtcaacc gggtgctcgg
    70741 catcgtcaac gggaccacca acttcatcct cgacgccatg gactcgaccg gggccggcta
    70801 tcaggaagcg ctcgacgagg ccacggccct cgggtacgcc gaggccgacc cgaccgccga
    70861 cgtcgagggc ttcgacgccg cagccaaggc cgccatcctc gccgggatcg ccttccacac
    70921 gcgcgtacgc ctcgacgacg tctaccgcga gggcatgacc gaggtcaccg ccgccgactt
    70981 cgcctccgcc aaggagatgg gctgcaccat caagctgctc gccatctgcg agcgggcggc
    71041 ggacggaggg tcggtcaccg cacgcgtgca tcccgcgatg atcccgctca gccatccgct
    71101 ggccaacgtg cgcgaggcgt acaacgccgt gttcgtggag tccgacgccg ccggtcagct
    71161 catgttctac gggcccggcg ccggcggttc gccgaccgcg tccgccgtgc tcggcgacct
    71221 ggtggccgtg tgccgcaacc ggctgggcgg agcgaccgga cccggtgagt ccgcgtacgc
    71281 cgccctgccc gtctccccga tgggcgacgt cgtcacgcgc taccacatca gcctcgacgt
    71341 ggccgacaaa ccgggcgtgc tcgcccaggt cgcgaccgtg ttcgcggagc acggtgtctc
    71401 catcgacacc gtgcggcagt ccggcaagga cggcgaggca tccctcgtcg tcgtcaccca
    71461 tcgcgcgtcc gacgccgccc tcggcggtac ggtcgaggcg ctgcgcaagc tcgacaccgt
    71521 gcggggtgtc gccagcatca tgcgggttga aggagagtaa ccagcaatga cccaccagtg
    71581 gcgcggaatc atcgaggagt accgggaccg gctgcccgtc tccgacagca cgcccgtcgt
    71641 gacgctccgt gagggcggca ccccgctcgt gcccgcgcag gtgctctccg agcgcacggg
    71701 ctgcgaggtc cacctcaagg tcgagggggc gaacccgacc gggtccttca aggaccgtgg
    71761 catgaccatg gccatcagca aggccaagga ggagggcgcg caggccgtca tctgcgcgtc
    71821 caccgggaac acgtccgcga gtgccgccgc gtacggcgtg cgcgcgggca tggtctccgc
    71881 cgtgctcgtg ccgcagggca agatcgcgct cggcaagatg ggccaggccc tcgtgcacgg
    71941 cgcgaagatc ctccaggtcg acggcaactt cgacgactgc ctcacgctgg cccgtgcgct
    72001 cagcgacaac tacccggtgg cactggtcaa ttcggtcaac ccggtgcgta tcgaggggca
    72061 gaagacggcc gccttcgaga tcgtggacat gctcggcgac gcgcccgaca tacatgtcct
    72121 tcccgtgggc aacgcgggca acatcaccgc gtactggaag gggtaccagg agtacgccgc
    72181 cgacggggtc agcaccaaga agccccgcat gtgggggttc caggcctccg gctccgcccc
    72241 gatcgtgcgc ggcgaggtcg tcaaggaccc gtcgaccatc gccaccgcca tccggatcgg
    72301 caaccccgcc tcgtgggact tcgcgctcgc cgcgcgcgac gagtcgggcg gcgccatcga
    72361 cgaggtgacg gaccgtgaga tcctgcgcgc ctaccggctg ttggcctcgc aggagggcgt
    72421 cttcgtggag cccgcctccg ccgcctccgt ggccggtctg ctgaaggccg ccgagcaggg
    72481 caaggtcgac ccggggcagc gcatcgtgtg caccgtcacc ggcaacgggc tgaaggaccc
    72541 gga
//
