LOCUS       NC_003888              72624 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    RefSeq; complete genome.
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces
            albidoflavus group.
REFERENCE   1  (bases 1 to 8667507)
  AUTHORS   Hsiao,N.H. and Kirby,R.
  TITLE     Comparative genomics of Streptomyces avermitilis, Streptomyces
            cattleya, Streptomyces maritimus and Kitasatospora aureofaciens
            using a Streptomyces coelicolor microarray system
  JOURNAL   Antonie Van Leeuwenhoek 93 (1-2), 1-25 (2008)
   PUBMED   17588127
REFERENCE   2  (bases 1 to 8667507)
  AUTHORS   Bentley,S.D., Chater,K.F., Cerdeno-Tarraga,A.M., Challis,G.L.,
            Thomson,N.R., James,K.D., Harris,D.E., Quail,M.A., Kieser,H.,
            Harper,D., Bateman,A., Brown,S., Chandra,G., Chen,C.W., Collins,M.,
            Cronin,A., Fraser,A., Goble,A., Hidalgo,J., Hornsby,T., Howarth,S.,
            Huang,C.H., Kieser,T., Larke,L., Murphy,L., Oliver,K., O'Neil,S.,
            Rabbinowitsch,E., Rajandream,M.A., Rutherford,K., Rutter,S.,
            Seeger,K., Saunders,D., Sharp,S., Squares,R., Squares,S., Taylor,K.,
            Warren,T., Wietzorrek,A., Woodward,J., Barrell,B.G., Parkhill,J. and
            Hopwood,D.A.
  TITLE     Complete genome sequence of the model actinomycete Streptomyces
            coelicolor A3(2)
  JOURNAL   Nature 417 (6885), 141-147 (2002)
   PUBMED   12000953
REFERENCE   3  (bases 1 to 8667507)
  AUTHORS   Redenbach,M., Kieser,H.M., Denapaite,D., Eichner,A., Cullum,J.,
            Kinashi,H. and Hopwood,D.A.
  TITLE     A set of ordered cosmids and a detailed genetic and physical map for
            the 8 Mb Streptomyces coelicolor A3(2) chromosome
  JOURNAL   Mol. Microbiol. 21 (1), 77-96 (1996)
   PUBMED   8843436
REFERENCE   4  (bases 1 to 8667507)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2002) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
  REMARK    Direct Submission
REFERENCE   5  (bases 1 to 8667507)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2002) Sanger Institute, Wellcome Trust Genome
            Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
  REMARK    Direct Submission
COMMENT     ##antiSMASH-Data-START##
            Version     :: 8.0.1
            Run date    :: 2025-05-26 12:13:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start :: 5494800
            Orig. end   :: 5567424
            ##antiSMASH-Data-END##
            REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..72624
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T2PKS"
                     /region_number="12"
                     /rules="(t2ks and t2clf)"
                     /tool="antismash"
     cand_cluster    1..72624
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..72624
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[35000:37624](+)"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="7 (Score: 743.5; E-value:
                     1.2e-226)"
                     /t2pks_molecular_weights="acetyl-CoA_7 (Da): 342.385"
                     /t2pks_product_classes="benzoisochromanequinone"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      35001..37624
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="7 (Score: 743.5; E-value:
                     1.2e-226)"
                     /t2pks_molecular_weights="acetyl-CoA_7 (Da): 342.385"
                     /t2pks_product_classes="benzoisochromanequinone"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     repeat_region   1252..1276
                     /note="3x degenerate repeat unit:
                     CAGCGCG(T/C)GCCGCGCGTGTGT(C/T)GCC"
     repeat_region   1362..1386
                     /note="3x degenerate repeat unit:
                     CAGCGCG(T/C)GCCGCGCGTGTGT(C/T)GCC"
     repeat_region   1472..1496
                     /note="3x degenerate repeat unit:
                     CAGCGCG(T/C)GCCGCGCGTGTGT(C/T)GCC"
     gene            complement(1674..3056)
                     /db_xref="GeneID:1100498"
                     /gene_synonym="SCK7.30c"
                     /locus_tag="SCO5057"
     CDS             complement(1674..3056)
                     /codon_start=1
                     /db_xref="GeneID:1100498"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCK7.30c"
                     /locus_tag="SCO5057"
                     /note="SCK7.30c, possible amino acid permease, len: 460 aa;
                     similar to SW:MMUP_ECOLI (EMBL:D83536) Escherichia coli
                     probable S-methylmethionine permease MmuP, 475 aa; fasta
                     scores: opt: 345 z-score: 390.5 E(): 2.8e-14; 23.3%
                     identity in 408 aa overlap and to TR:P74848 (EMBL:X99945)
                     Salmonella typhimurium amino acid permease YeeF like
                     protein, 448 aa; fasta scores: opt: 705 z-score: 792.4 E():
                     0; 32.0% identity in 416 aa overlap. Contains Pfam match to
                     entry PF00324 aa_permeases, Amino acid permease and
                     possible hydrophobic membrane spanning regions"
                     /product="amino acid permease"
                     /protein_id="NP_629209.1"
                     /transl_table=11
                     /translation="MAQSGTTAPEAGGEERLRRSLGFRDLVVYGLLFIAPMAPVGVFGT
                     LDAKSHGAVALVYLVATVAMAFTAFSYAQMVRVVPQAGSVFAYARAGLGNGAGFVAGWM
                     AMLDYILIPAVAYLFSGIAMEALVPEVSRWVWTAIAVVVTTLLNLWGVRTAARVGFLVL
                     AMEIVVLLVFVATAIVVLAQDGAERDWLSPLSGDGTQGAFALSAVVGAVSVAVLSYLGF
                     DAIATFAEEVTGGSAKVARALLFCLALAGVLFVAQTYLVALLEPVSSAQLAAEPERQGS
                     AFYDAVDVSVGTWLHDLVAVSKAIGAAFAALAGQAAAGRLLFAMGRDRRLPGVLARTDA
                     GVPRVALLVSAVITMAAAVWAARRDDGLDHLVSVVDVGALTAFTLLHASVVGWFVVRRG
                     GGRVIWWRHLLVPVLGAAITIAVIVEASGTAQVVGAIWLAVGLVVLAAQWRGRRDAETT
                     GA"
     misc_feature    complement(1698..2933)
                     /gene_synonym="SCK7.30c"
                     /locus_tag="SCO5057"
                     /note="Pfam match to entry PF00324 aa_permeases, Amino acid
                     permease, score -171.30, E-value 2.7e-06"
     PFAM_domain     complement(1890..2924)
                     /aSDomain="AA_permease"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00324.24"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Amino acid permease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5057_0406"
                     /evalue="3.00E-33"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO5057"
                     /locus_tag="SCO5057"
                     /protein_end="389"
                     /protein_start="44"
                     /score="115.3"
                     /tool="antismash"
                     /translation="TLDAKSHGAVALVYLVATVAMAFTAFSYAQMVRVVPQAGSVFAYA
                     RAGLGNGAGFVAGWMAMLDYILIPAVAYLFSGIAMEALVPEVSRWVWTAIAVVVTTLLN
                     LWGVRTAARVGFLVLAMEIVVLLVFVATAIVVLAQDGAERDWLSPLSGDGTQGAFALSA
                     VVGAVSVAVLSYLGFDAIATFAEEVTGGSAKVARALLFCLALAGVLFVAQTYLVALLEP
                     VSSAQLAAEPERQGSAFYDAVDVSVGTWLHDLVAVSKAIGAAFAALAGQAAAGRLLFAM
                     GRDRRLPGVLARTDAGVPRVALLVSAVITMAAAVWAARRDDGLDHLVSVVDVGALTAFT
                     LLHAS"
     regulatory      complement(3061..3065)
                     /regulatory_class="ribosome_binding_site"
     gene            3185..4201
                     /db_xref="GeneID:1100499"
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /locus_tag="SCO5058"
     CDS             3185..4201
                     /EC_number="1.17.1.2"
                     /codon_start=1
                     /db_xref="GeneID:1100499"
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /locus_tag="SCO5058"
                     /note="catalyzes the conversion of
                     1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into
                     isopentenyl diphosphate (IPP) and dimethylallyl diphosphate
                     (DMAPP); functions in the nonmevalonate isoprenoid
                     biosynthesis pathway"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="NP_733653.1"
                     /transl_table=11
                     /translation="MGAMTASPGRRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPVYVR
                     HEIVHNKYVVQTLEKKGAIFVERTEEVPEGNIVMFSAHGVAPVVHEEAERGKLATIDAT
                     CPLVTKVHKEAVRFANDDYDILLIGHEGHEEVIGTSGEAPDHIQLVDGPEDVAKVEVRD
                     PSKVVWLSQTTLSVDETMETVDALKDKFPQLISPPSDDICYATQNRQLAVKQMGAEAEL
                     VIVVGSRNSSNSKRLVEVAKQAGSRAAYLVDFADEIDETWLDGVTTVGVTSGASVPDVL
                     VEQVLEWLSRRGFEDVEIVKAAEESIIFSLPKELRRDLREEAASLVAERGGSGTAGA"
     aSDomain        3218..4051
                     /aSDomain="TIGR00216"
                     /aSTool="tigrfam"
                     /description="ispH_lytB: 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5058_0048"
                     /evalue="1.90E-97"
                     /identifier="TIGR00216"
                     /label="SCO5058"
                     /locus_tag="SCO5058"
                     /protein_end="289"
                     /protein_start="11"
                     /score="323.8"
                     /tool="antismash"
                     /translation="VLLAAPRGYCAGVDRAVIAVEKALEQYGAPVYVRHEIVHNKYVVQ
                     TLEKKGAIFVERTEEVPEGNIVMFSAHGVAPVVHEEAERGKLATIDATCPLVTKVHKEA
                     VRFANDDYDILLIGHEGHEEVIGTSGEAPDHIQLVDGPEDVAKVEVRDPSKVVWLSQTT
                     LSVDETMETVDALKDKFPQLISPPSDDICYATQNRQLAVKQMGAEAELVIVVGSRNSSN
                     SKRLVEVAKQAGSRAAYLVDFADEIDETWLDGVTTVGVTSGASVPDVLVEQVLEWL"
     PFAM_domain     3218..4051
                     /aSDomain="LYTB"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02401.21"
                     /db_xref="GO:0019288"
                     /db_xref="GO:0046872"
                     /db_xref="GO:0050992"
                     /db_xref="GO:0051745"
                     /description="LytB protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5058_0407"
                     /evalue="4.90E-89"
                     /gene_ontologies="GO:0019288: isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway"
                     /gene_ontologies="GO:0046872: metal ion binding"
                     /gene_ontologies="GO:0050992: dimethylallyl diphosphate
                     biosynthetic process"
                     /gene_ontologies="GO:0051745:
                     4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase
                     activity"
                     /label="SCO5058"
                     /locus_tag="SCO5058"
                     /protein_end="289"
                     /protein_start="11"
                     /score="298.3"
                     /tool="antismash"
                     /translation="VLLAAPRGYCAGVDRAVIAVEKALEQYGAPVYVRHEIVHNKYVVQ
                     TLEKKGAIFVERTEEVPEGNIVMFSAHGVAPVVHEEAERGKLATIDATCPLVTKVHKEA
                     VRFANDDYDILLIGHEGHEEVIGTSGEAPDHIQLVDGPEDVAKVEVRDPSKVVWLSQTT
                     LSVDETMETVDALKDKFPQLISPPSDDICYATQNRQLAVKQMGAEAELVIVVGSRNSSN
                     SKRLVEVAKQAGSRAAYLVDFADEIDETWLDGVTTVGVTSGASVPDVLVEQVLEWL"
     misc_feature    3755..4060
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /locus_tag="SCO5058"
                     /note="Pfam match to entry PF02401 LYTB, LytB protein,
                     score -87.40, E-value 2.5e-05"
     gene            4255..4995
                     /db_xref="GeneID:1100500"
                     /gene_synonym="ppgK; SCBAC20F6.02"
                     /locus_tag="SCO5059"
     CDS             4255..4995
                     /codon_start=1
                     /db_xref="GeneID:1100500"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /gene_synonym="ppgK; SCBAC20F6.02"
                     /locus_tag="SCO5059"
                     /note="SCBAC20F6.02, ppgK, polyphosphate glucokinase, len:
                     246 aa; highly similar to SW:PPGK_MYCTU (EMBL:U44834)
                     Mycobacterium tuberculosis polyphosphate glucokinase (EC
                     2.7.1.63) PpgK or RV2702 or MTCY05A6.23, 265 aa; fasta
                     scores: opt: 912 Z-score: 1042.8 bits: 200.5 E(): 1.7e-50;
                     57.322% identity in 239 aa overlap. Contains Pfam match to
                     entry PF00480 ROK, ROK family"
                     /product="polyphosphate glucokinase"
                     /protein_id="NP_629210.1"
                     /transl_table=11
                     /translation="MQIFGVDIGGSGIKGAPVDLDRGDLAQERCKVLTPHPATPDGVAD
                     GVKQVVEHFGWTGRVGLTFPGVVTGGATVRTAANVDKGWVDTDARALFAERLGGLDVTV
                     VNDADAAGVAEMHFGAGRGRKGTVVLLTFGTGIGSAVFTDGLLVPNTELGHLELDGHDA
                     EKRASSKVKDDHDMSWEHWAHRVQKYLAHVEMLFSPELFIIGGGVSRKSQKFLPHIKDV
                     RAEIVPAQLQNNAGIVGAAMHAAG"
     PFAM_domain     4264..4740
                     /aSDomain="ROK"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00480.23"
                     /description="ROK family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5059_0408"
                     /evalue="1.00E-15"
                     /label="SCO5059"
                     /locus_tag="SCO5059"
                     /protein_end="162"
                     /protein_start="3"
                     /score="58.2"
                     /tool="antismash"
                     /translation="FGVDIGGSGIKGAPVDLDRGDLAQERCKVLTPHPATPDGVADGVK
                     QVVEHFGWTGRVGLTFPGVVTGGATVRTAANVDKGWVDTDARALFAERLGGLDVTVVND
                     ADAAGVAEMHFGAGRGRKGTVVLLTFGTGIGSAVFTDGLLVPNTELGHLELDGHD"
     misc_feature    4267..4677
                     /gene_synonym="ppgK; SCBAC20F6.02"
                     /locus_tag="SCO5059"
                     /note="Pfam match to entry PF00480 ROK, ROK family, score
                     21.60, E-value 2.4e-05"
     gene            complement(5006..5608)
                     /db_xref="GeneID:1100501"
                     /gene_synonym="SCBAC20F6.03c"
                     /locus_tag="SCO5060"
     CDS             complement(5006..5608)
                     /codon_start=1
                     /db_xref="GeneID:1100501"
                     /gene_synonym="SCBAC20F6.03c"
                     /locus_tag="SCO5060"
                     /note="SCBAC20F6.03c, possible integral membrane protein,
                     len: 200 aa. Contains possible hydrophobic membrane
                     spanning regions and high G+C content in N-terminal region"
                     /product="hypothetical protein"
                     /protein_id="NP_629211.1"
                     /transl_table=11
                     /translation="MEQHRTRPAQYGPRRSGAPLPAQGRGGAVARPPAGRVGPPAGRRP
                     EPVRPAPGAPSPVARVVRALRGMPNPRLTGLGSGLFCAAVMTLLGFLDELLFGSSLTAY
                     GVLFVPVSLLTALWVRRGDLLTAPVVVPIAFAVGLVPVAESGDGGLGGRLMGIVTALAT
                     EAGWLYGGTLVAGSTVIVRRIRLMRRRAAAARNRPPA"
     PFAM_domain     complement(5048..5395)
                     /aSDomain="DUF6542"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF20177.1"
                     /description="Domain of unknown function (DUF6542)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5060_0409"
                     /evalue="2.80E-19"
                     /label="SCO5060"
                     /locus_tag="SCO5060"
                     /protein_end="187"
                     /protein_start="71"
                     /score="69.3"
                     /tool="antismash"
                     /translation="RLTGLGSGLFCAAVMTLLGFLDELLFGSSLTAYGVLFVPVSLLTA
                     LWVRRGDLLTAPVVVPIAFAVGLVPVAESGDGGLGGRLMGIVTALATEAGWLYGGTLVA
                     GSTVIVRRIRLM"
     misc_feature    complement(5374..5584)
                     /gene_synonym="SCBAC20F6.03c"
                     /locus_tag="SCO5060"
                     /note="high G+C content region (82.46%)"
     aSDomain        5794..6879
                     /aSDomain="TIGR00092"
                     /aSTool="tigrfam"
                     /description="TIGR00092: GTP-binding protein YchF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5061_0049"
                     /evalue="1.40E-132"
                     /identifier="TIGR00092"
                     /label="SCO5061"
                     /locus_tag="SCO5061"
                     /protein_end="362"
                     /protein_start="0"
                     /score="440.3"
                     /tool="antismash"
                     /translation="MSLTIGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVG
                     VPDPRLTKLAEIFSSEKILPATVDFVDIAGIVRGASEGEGLGNKFLANIRESDAICQVI
                     RAFKDENVVHVDGKVSPKDDIETINTELILADLQTIEKVLPRLQKESRIKKDVAPKVKA
                     VEEAKEILEKGDTLFSQGILQGSERAELLHDLHLLTTKPFLYVFNVDEDELTDDDFKSE
                     QRALVAPAEAIFLNAKLEADLAELDEDEALELLQSVGQDEPGLATLAHVGFRTLGLQTY
                     LTAGPKESRAWTIKKGATAPEAAGVIHTDFQKGFIKAEVISFDDLVETGSVTEARAKGK
                     ARMEGKEYVMRDGDVVEFRFNV"
     gene            5794..6882
                     /db_xref="GeneID:1100502"
                     /gene_synonym="ychF"
                     /locus_tag="SCO5061"
     CDS             5794..6882
                     /codon_start=1
                     /db_xref="GeneID:1100502"
                     /gene_synonym="ychF"
                     /locus_tag="SCO5061"
                     /note="translation-associated GTPase; the crystal structure
                     of the Haemophilus influenzae YchF protein showed
                     similarity to the yeast structure (PDB: 1NI3); fluorescence
                     spectroscopy revealed nucleic acid binding; the yeast
                     protein YBR025c interacts with the translation elongation
                     factor eEF1"
                     /product="GTP-dependent nucleic acid-binding protein EngD"
                     /protein_id="NP_629212.1"
                     /transl_table=11
                     /translation="MSLTIGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVG
                     VPDPRLTKLAEIFSSEKILPATVDFVDIAGIVRGASEGEGLGNKFLANIRESDAICQVI
                     RAFKDENVVHVDGKVSPKDDIETINTELILADLQTIEKVLPRLQKESRIKKDVAPKVKA
                     VEEAKEILEKGDTLFSQGILQGSERAELLHDLHLLTTKPFLYVFNVDEDELTDDDFKSE
                     QRALVAPAEAIFLNAKLEADLAELDEDEALELLQSVGQDEPGLATLAHVGFRTLGLQTY
                     LTAGPKESRAWTIKKGATAPEAAGVIHTDFQKGFIKAEVISFDDLVETGSVTEARAKGK
                     ARMEGKEYVMRDGDVVEFRFNV"
     misc_feature    5806..5925
                     /gene_synonym="ychF"
                     /locus_tag="SCO5061"
                     /note="Pfam match to entry PF01018 GTP1_OBG, GTP1/OBG
                     family, score 15.50, E-value 0.00092"
     PFAM_domain     5806..6141
                     /aSDomain="MMR_HSR1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01926.26"
                     /db_xref="GO:0005525"
                     /description="50S ribosome-binding GTPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5061_0410"
                     /evalue="1.60E-22"
                     /gene_ontologies="GO:0005525: GTP binding"
                     /label="SCO5061"
                     /locus_tag="SCO5061"
                     /protein_end="116"
                     /protein_start="4"
                     /score="79.8"
                     /tool="antismash"
                     /translation="IGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVGVPDP
                     RLTKLAEIFSSEKILPATVDFVDIAGIVRGASEGEGLGNKFLANIRESDAICQVIRAFK
                     DENVVHVD"
     misc_feature    5818..5841
                     /gene_synonym="ychF"
                     /locus_tag="SCO5061"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     misc_feature    5839..5852
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     PFAM_domain     6625..6876
                     /aSDomain="YchF-GTPase_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF06071.16"
                     /description="Protein of unknown function (DUF933)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5061_0411"
                     /evalue="1.40E-37"
                     /label="SCO5061"
                     /locus_tag="SCO5061"
                     /protein_end="361"
                     /protein_start="277"
                     /score="127.9"
                     /tool="antismash"
                     /translation="LQTYLTAGPKESRAWTIKKGATAPEAAGVIHTDFQKGFIKAEVIS
                     FDDLVETGSVTEARAKGKARMEGKEYVMRDGDVVEFRFN"
     gene            complement(7004..7396)
                     /db_xref="GeneID:1100503"
                     /gene_synonym="SCBAC20F6.05c"
                     /locus_tag="SCO5062"
     CDS             complement(7004..7396)
                     /codon_start=1
                     /db_xref="GeneID:1100503"
                     /gene_synonym="SCBAC20F6.05c"
                     /locus_tag="SCO5062"
                     /note="SCBAC20F6.05c, hypothetical protein, len: 130 aa;
                     similar to TR:Q9X8E7 (EMBL:AL049573) Streptomyces
                     coelicolor hypothetical 16.4 kDa protein SCE39.24, 148 aa;
                     fasta scores: opt: 257 Z-score: 327.8 bits: 66.5 E():
                     1.1e-10; 39.394% identity in 132 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_629213.1"
                     /transl_table=11
                     /translation="MPGTLLLDSEGLSKLYRKDRTVMALVQAAAEEGVRVATSAMTTLE
                     ADYERIHPARIKWILSRVDVHDVTKEITDQAAALLRAHRLHGHTYAIDAAFAVIARDAS
                     RPVTVLTSDPEDLTLLCGPSVGVVKV"
     gene            complement(7396..7647)
                     /db_xref="GeneID:1100504"
                     /gene_synonym="SCBAC20F6.06c"
                     /locus_tag="SCO5063"
     CDS             complement(7396..7647)
                     /codon_start=1
                     /db_xref="GeneID:1100504"
                     /gene_synonym="SCBAC20F6.06c"
                     /locus_tag="SCO5063"
                     /note="SCBAC20F6.06c, hypothetical protein, len: 83 aa;
                     similar to TR:Q9XAG7 (EMBL:AL079356) Streptomyces
                     coelicolor hypothetical 8.8 kDa protein SC6G9.07, 84 aa;
                     fasta scores: opt: 167 Z-score: 224.6 bits: 45.9 E():
                     6.3e-05; 43.103% identity in 58 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_629214.1"
                     /transl_table=11
                     /translation="MSGSRKYSISLPEDLAEAVRAHVGPGGFSAYVAEALEQRVAMDKL
                     REIVADFETDNEALTHEEVEAARALLRHDHRQAGGAAA"
     gene            7646..10048
                     /db_xref="GeneID:1100505"
                     /gene_synonym="SCBAC20F6.07"
                     /locus_tag="SCO5064"
     CDS             7646..10048
                     /codon_start=1
                     /db_xref="GeneID:1100505"
                     /gene_synonym="SCBAC20F6.07"
                     /locus_tag="SCO5064"
                     /note="SCBAC20F6.07, possible bifunctional protein, len:
                     800 aa; N-terminal domain does not present similarity to
                     any known protein and C-terminal half is similar to the
                     C-terminal domain of may prokaryotic helicases, e.g.
                     TR:Q9CE08 (EMBL:AE006434) Lactococcus lactis (subsp.
                     lactis) SWI/SNF family helicase Snf, 1034 aa; fasta scores:
                     opt: 317 Z-score: 332.6 bits: 72.8 E(): 6.1e-11; 29.817%
                     identity in 436 aa overlap. Contains Pfam match to entry
                     PF00176 SNF2_N, SNF2 and others N-terminal domain and Pfam
                     match to entry PF00271 helicase_C, Helicase conserved
                     C-terminal domain"
                     /product="hypothetical protein"
                     /protein_id="NP_629215.1"
                     /transl_table=11
                     /translation="MVPILPAVVSLGGEWLPRGSVDQQGAVNARRGPVWAVERCGEGQR
                     GAGSVGRGERDTVARGTRLYEAAQAVVGDHARAVEAVRAALKPIHDEAVKRELDAIPVA
                     RLQDVTEGRLRLGSVEKSGLRTLGRVLEAGPYRLRQIPGVGQRTVDQILAAARRLSEAV
                     HETVAVHIDVDRPEPRTTALVMALHVLVEAGPEARRAVDKATVLTERLGPLLADAGPAA
                     GRVRMLLAGREKKARAWAAVAATRSLVDEAEQAGLPGLLAQASVDLLRGTASDVAAWVD
                     FELRSAEYYSLLAEISGRPPDAAAVEGFLPDEVAERVRTQHLDDTHRRVSLRGYQAFGA
                     RFALAQRKVILGDEMGLGKTIQAIAVLAHLAAEGQSHFMVVCPASVLVNWTREIEARSA
                     LRVMVLHGPDRHYAFADWKGRGGVGVTTFDALRGFPAPGGGEVGLLVVDEAHSVKNPKA
                     KRSQAVGLWAERCERTLFMTGTPMENRVAEFRNLVQMLDGDVADSLGERDALAGSVTFR
                     KAVAPVYLRRNQEDVLTELPSLQQTDEWEELSASDEEAYREAVRAGNFMAMRRAAYMSS
                     GNSAKLERLREIVQEAGENGQKTVVFSNFKDVLAVVKEALAVETTRVTPVFGPLTGGVP
                     AQRRQEIVDDFAGVQGPAVLLGQIQAAGVGLNMQAASVVVICEPQIKPTIEHQAVARAH
                     RMGQVRPVRVHRLLATGGVDERMVKMLEAKTRLFDAYARRSAVAEATPDAVDVSDTELA
                     RRIVEEEQARLGMTDERPTSSEWGVPRSAASPQDPLNGRRESTNANE"
     misc_feature    8648..9124
                     /gene_synonym="SCBAC20F6.07"
                     /locus_tag="SCO5064"
                     /note="Pfam match to entry PF00176 SNF2_N, SNF2 and others
                     N-terminal domain, score 94.40, E-value 5.5e-25"
     PFAM_domain     8684..9382
                     /aSDomain="SNF2-rel_dom"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00176.26"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0140658"
                     /description="SNF2-related domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5064_0412"
                     /evalue="9.60E-31"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0140658: ATP-dependent chromatin
                     remodeler activity"
                     /label="SCO5064"
                     /locus_tag="SCO5064"
                     /protein_end="579"
                     /protein_start="346"
                     /score="107.0"
                     /tool="antismash"
                     /translation="RKVILGDEMGLGKTIQAIAVLAHLAAEGQSHFMVVCPASVLVNWT
                     REIEARSALRVMVLHGPDRHYAFADWKGRGGVGVTTFDALRGFPAPGGGEVGLLVVDEA
                     HSVKNPKAKRSQAVGLWAERCERTLFMTGTPMENRVAEFRNLVQMLDGDVADSLGERDA
                     LAGSVTFRKAVAPVYLRRNQEDVLTELPSLQQTDEWEELSASDEEAYREAVRAGNFMAM
                     RRAAYMSSGNS"
     PFAM_domain     9386..9736
                     /aSDomain="Helicase_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00271.34"
                     /description="Helicase conserved C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5064_0413"
                     /evalue="3.70E-11"
                     /label="SCO5064"
                     /locus_tag="SCO5064"
                     /protein_end="697"
                     /protein_start="580"
                     /score="43.5"
                     /tool="antismash"
                     /translation="KLERLREIVQEAGENGQKTVVFSNFKDVLAVVKEALAVETTRVTP
                     VFGPLTGGVPAQRRQEIVDDFAGVQGPAVLLGQIQAAGVGLNMQAASVVVICEPQIKPT
                     IEHQAVARAHRMG"
     misc_feature    9485..9736
                     /gene_synonym="SCBAC20F6.07"
                     /locus_tag="SCO5064"
                     /note="Pfam match to entry PF00271 helicase_C, Helicase
                     conserved C-terminal domain, score 31.50, E-value 2e-05"
     gene            complement(10137..12968)
                     /db_xref="GeneID:1100506"
                     /gene_synonym="SCBAC20F6.08c"
                     /locus_tag="SCO5065"
     CDS             complement(10137..12968)
                     /codon_start=1
                     /db_xref="GeneID:1100506"
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="SCBAC20F6.08c"
                     /locus_tag="SCO5065"
                     /note="SCBAC20F6.08c, possible transcriptional regulator,
                     len: 943 aa; similar to many transcriptional regulatory
                     proteins, e.g. TR:Q9XAT8 (EMBL:U95170) Rhodococcus
                     erythropolis ThcG, 927 aa; fasta scores: opt: 1419 Z-score:
                     1371.5 bits: 265.1 E(): 8.4e-69; 35.446% identity in 931 aa
                     overlap. Contains Pfam match to entry PF00196 GerE,
                     Bacterial regulatory proteins, luxR family and matches to
                     Prosite entries PS00017 ATP/GTP-binding site motif A
                     (P-loop) and PS00622 Bacterial regulatory proteins, luxR
                     family signature. Also contains possible helix-turn-helix
                     motif at residues 893..914 (+3.76 SD)"
                     /product="transcriptional regulator"
                     /protein_id="NP_629216.1"
                     /transl_table=11
                     /translation="MKNGERARAGHGSPAAPGPTAGPGPAPAPGPTVVGREAEIAEIRS
                     RIAADRSHSSVLIVEGDPGAGKSVLLDLAVRLTRGTGQRVLRAVGSESEASLAFAGLHQ
                     MLRPVLDDLGGLPARQRSALRTALGLAEDAEDAADTPDALLVGLAVLTLVSDLSEPAPL
                     LVVVDDAQWIDRASLDVLSFLARRMAGEPVTLLMGVRAAAVLPGFDKGYERLEIGPLSG
                     DAANRLLDEQPKRPTGRTRARILREAAGNPLALVELARATADREPEGSGVEGPLPVTDR
                     LEGIFARHVRHLPEATRRALLLLAAADAADAPAAARGLPEAADTVWAPAERAGLVRQDG
                     TGVSFRHPLVRSAVYHAAPFEQRRRAHLALARQLGEEPDRRAWHLAAAAVRPDEQVSAA
                     LRETAGRARRRGGHAAAAAALERAAELSPHRADQARLLADAADTAVFTGQLGWVEHLAA
                     GARERSDDPALIGRAALATGRLLTLGPHHTAAFALLSRVADEAAATRSPRLLDALAAAA
                     VVRYYSGEESQRQRIEALLADVPDSAAGGALRAWVLAVSDPSGAGASLAPALPRLIAAA
                     KGEAGSLTALAVVAWLLDRTPLAARTFDEAFGRWQAHGPLPAGLACAAGWAYLEQGRWA
                     DARSVAAEIAEVASGAGLDHAEACARTLDATVLALLGEPAEARGSAERALALVAPLESR
                     SVAVLARRALGLAAVAEGDYDSAYAQFRAAFTEDGDLVHYHVSPTVLAELAAAAVRRGH
                     REPAARLLERSARHLGPGMSARLFLLVERGRALLAEPERAERHFRAALAGEAGEQWPFE
                     RAQTRLDYGEWLRRQRRVAEARPLLTGALDTFRRLGARPWIDRAKAELRAAGIEADAAA
                     PGALTELSPQQQQIVRLAAHGLTNREIGERLFLSPRTVGSHLYRVFPKLGITARAQLRD
                     LLDDALQATGSAQ"
     misc_feature    complement(10149..10346)
                     /gene_synonym="SCBAC20F6.08c"
                     /locus_tag="SCO5065"
                     /note="Pfam match to entry PF00196 GerE, Bacterial
                     regulatory proteins, luxR family, score 55.50, E-value
                     1.2e-12"
     PFAM_domain     complement(10182..10337)
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00196.22"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5065_0415"
                     /evalue="7.70E-13"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO5065"
                     /locus_tag="SCO5065"
                     /protein_end="929"
                     /protein_start="877"
                     /score="47.9"
                     /tool="antismash"
                     /translation="LSPQQQQIVRLAAHGLTNREIGERLFLSPRTVGSHLYRVFPKLGI
                     TARAQLR"
     misc_feature    complement(10212..10295)
                     /gene_synonym="SCBAC20F6.08c"
                     /locus_tag="SCO5065"
                     /note="PS00622 Bacterial regulatory proteins, luxR family
                     signature"
     PFAM_domain     complement(12390..12872)
                     /aSDomain="AAA_16"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13191.9"
                     /description="AAA ATPase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5065_0414"
                     /evalue="1.60E-17"
                     /label="SCO5065"
                     /locus_tag="SCO5065"
                     /protein_end="193"
                     /protein_start="32"
                     /score="64.5"
                     /tool="antismash"
                     /translation="VVGREAEIAEIRSRIAADRSHSSVLIVEGDPGAGKSVLLDLAVRL
                     TRGTGQRVLRAVGSESEASLAFAGLHQMLRPVLDDLGGLPARQRSALRTALGLAEDAED
                     AADTPDALLVGLAVLTLVSDLSEPAPLLVVVDDAQWIDRASLDVLSFLARRMAGEPV"
     misc_feature    complement(12765..12788)
                     /gene_synonym="SCBAC20F6.08c"
                     /locus_tag="SCO5065"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     regulatory      complement(12974..12977)
                     /regulatory_class="ribosome_binding_site"
     regulatory      13268..13271
                     /regulatory_class="ribosome_binding_site"
     gene            13278..14192
                     /db_xref="GeneID:1100507"
                     /gene_synonym="SCBAC20F6.09"
                     /locus_tag="SCO5066"
     CDS             13278..14192
                     /codon_start=1
                     /db_xref="GeneID:1100507"
                     /gene_synonym="SCBAC20F6.09"
                     /locus_tag="SCO5066"
                     /note="SCBAC20F6.09, possible beta-lactamase, len: 304 aa;
                     similar to TR:Q9X7X2 (EMBL:AL049485) Streptomyces
                     coelicolor beta-lactamase SC6E5.26c, 310 aa; fasta scores:
                     opt: 598 Z-score: 696.3 bits: 136.9 E(): 3.4e-31; 53.115%
                     identity in 305 aa overlap and to SW:BLA1_XANMA
                     (EMBL:X75074) Xanthomonas maltophilia
                     metallo-beta-lactamase L1 precursor (beta-lactamase, type
                     II) (EC 3.5.2.6), 290 aa; fasta scores: opt: 146 Z-score:
                     175.9 bits: 40.6 E(): 0.033; 25.952% identity in 289 aa
                     overlap. Contains Pfam match to entry PF00753 lactamase_B,
                     Metallo-beta-lactamase superfamily and match to Prosite
                     entry PS00136 Serine proteases, subtilase family, aspartic
                     acid active site"
                     /product="beta-lactamase"
                     /protein_id="NP_629217.1"
                     /transl_table=11
                     /translation="MDTITLGDVTVTRVREYYGPVGMTPEAFVPDSPAQAWDTHRSWLV
                     PDFLDAETRIVNTAIQTWVLRSEGRTILVDTGVGNHKDRPYAPVWSRLETDFLANLARA
                     GVQPEDVDIVINTHLHIDHVGWNTYLDGRTWVPTFPNATYLMAKADFDYWNPANEIKTL
                     LGRGNQNVFEDSVAPVHEAGLTRLWEDGHRIDSNLRLELAPGHTPGSSVLRLESGSDRG
                     LFVGDLMHSPIQIHEPDANSCFCEDPAEARATRRRLLGSAVDSNALVFPAHLGGHGAAE
                     VVREGGKFAVKGWAPFTPYTPSV"
     misc_feature    13287..13301
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     misc_feature    13440..14096
                     /gene_synonym="SCBAC20F6.09"
                     /locus_tag="SCO5066"
                     /note="Pfam match to entry PF00753 lactamase_B,
                     Metallo-beta-lactamase superfamily, score 53.00, E-value
                     6.4e-12"
     PFAM_domain     13458..14096
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00753.30"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5066_0416"
                     /evalue="1.50E-32"
                     /label="SCO5066"
                     /locus_tag="SCO5066"
                     /protein_end="273"
                     /protein_start="60"
                     /score="113.3"
                     /tool="antismash"
                     /translation="QTWVLRSEGRTILVDTGVGNHKDRPYAPVWSRLETDFLANLARAG
                     VQPEDVDIVINTHLHIDHVGWNTYLDGRTWVPTFPNATYLMAKADFDYWNPANEIKTLL
                     GRGNQNVFEDSVAPVHEAGLTRLWEDGHRIDSNLRLELAPGHTPGSSVLRLESGSDRGL
                     FVGDLMHSPIQIHEPDANSCFCEDPAEARATRRRLLGSAVDSNALVFPAH"
     misc_feature    13488..13520
                     /gene_synonym="SCBAC20F6.09"
                     /locus_tag="SCO5066"
                     /note="PS00136 Serine proteases, subtilase family, aspartic
                     acid active site"
     regulatory      14201..14206
                     /regulatory_class="ribosome_binding_site"
     gene            14215..15708
                     /db_xref="GeneID:1100508"
                     /gene_synonym="SCBAC20F6.10"
                     /locus_tag="SCO5067"
     CDS             14215..15708
                     /codon_start=1
                     /db_xref="GeneID:1100508"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCBAC20F6.10"
                     /locus_tag="SCO5067"
                     /note="SCBAC20F6.10, probable carboxylesterase, len: 497
                     aa; similar to SW:PNBA_BACSU (EMBL:U06089) Bacillus
                     subtilis para-nitrobenzyl esterase (EC 3.1.1.*) PnbA, 489
                     aa; fasta scores: opt: 784 Z-score: 827.6 bits: 162.6 E():
                     1.6e-38; 37.205% identity in 508 aa overlap. Contains 2x
                     Pfam matches to entry PF00135 COesterase, Carboxylesterase
                     and match to Prosite entry PS00122 Carboxylesterases type-B
                     serine active site"
                     /product="carboxylesterase"
                     /protein_id="NP_629218.1"
                     /transl_table=11
                     /translation="MNHHPEPVVTTAQGAVRGLRQEDGTAAFLNIPYAAPPLGAGRFAP
                     PRPHEPWDGVRDATVPGPNAPQSERRLGSIDMAPYFGTGWSRGEDYLTVNVFTPATGAG
                     DLPVMVFVHGGGFVAGSTRSAMYDGSAFARDGVVLVTLNYRLGIAGFLDIPGAPANRGL
                     LDVVAALRWVRENVSAFGGNPHHVTLFGQSAGATVVGGVLATPEADGLFRRAIVQSGSG
                     LGAFTPEQAARVTAAAAQALGVEPHVDAFAGIPDERLVEAASGLAGIDLRTGTHFDPLI
                     GLSPFSLVLDTQPAASVAAGRAADVDLLVGTNTEEGNLYLVPVGKYATSTAADVDEAAA
                     RAHPDPAQLVAAYRTSRPEATFAELRSAVMADALFGAGSRALASAHATHPRAATYAYEF
                     AWRSRALDGELGATHAVELPFVFDLADRPELNGPAALLGPEQAPADLAARVHATWIRFA
                     RTGDPGWDPYDTDRRATMRIDAEWSQTDDPRSKEREVWS"
     PFAM_domain     14230..15696
                     /aSDomain="COesterase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00135.31"
                     /description="Carboxylesterase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5067_0417"
                     /evalue="8.90E-95"
                     /label="SCO5067"
                     /locus_tag="SCO5067"
                     /protein_end="494"
                     /protein_start="5"
                     /score="318.7"
                     /tool="antismash"
                     /translation="EPVVTTAQGAVRGLRQEDGTAAFLNIPYAAPPLGAGRFAPPRPHE
                     PWDGVRDATVPGPNAPQSERRLGSIDMAPYFGTGWSRGEDYLTVNVFTPATGAGDLPVM
                     VFVHGGGFVAGSTRSAMYDGSAFARDGVVLVTLNYRLGIAGFLDIPGAPANRGLLDVVA
                     ALRWVRENVSAFGGNPHHVTLFGQSAGATVVGGVLATPEADGLFRRAIVQSGSGLGAFT
                     PEQAARVTAAAAQALGVEPHVDAFAGIPDERLVEAASGLAGIDLRTGTHFDPLIGLSPF
                     SLVLDTQPAASVAAGRAADVDLLVGTNTEEGNLYLVPVGKYATSTAADVDEAAARAHPD
                     PAQLVAAYRTSRPEATFAELRSAVMADALFGAGSRALASAHATHPRAATYAYEFAWRSR
                     ALDGELGATHAVELPFVFDLADRPELNGPAALLGPEQAPADLAARVHATWIRFARTGDP
                     GWDPYDTDRRATMRIDAEWSQTDDPRSKERE"
     misc_feature    14233..15165
                     /gene_synonym="SCBAC20F6.10"
                     /locus_tag="SCO5067"
                     /note="Pfam match to entry PF00135 COesterase,
                     Carboxylesterase, score 253.00, E-value 6e-73"
     misc_feature    14752..14799
                     /gene_synonym="SCBAC20F6.10"
                     /locus_tag="SCO5067"
                     /note="PS00122 Carboxylesterases type-B serine active site"
     misc_feature    15319..15702
                     /gene_synonym="SCBAC20F6.10"
                     /locus_tag="SCO5067"
                     /note="Pfam match to entry PF00135 COesterase,
                     Carboxylesterase, score 47.70, E-value 3.2e-13"
     gene            complement(15716..16315)
                     /db_xref="GeneID:1100509"
                     /gene_synonym="SCBAC20F6.11c"
                     /locus_tag="SCO5068"
     CDS             complement(15716..16315)
                     /codon_start=1
                     /db_xref="GeneID:1100509"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="SCBAC20F6.11c"
                     /locus_tag="SCO5068"
                     /note="SCBAC20F6.11c, possible tetR-family transcriptional
                     regulator, len: 199 aa; similar to many actinomycetes
                     tetR-family transcriptional regulators, e.g. TR:Q9RJL5
                     (EMBL:AL121849) Streptomyces coelicolor tetR-family
                     transcriptional regulator SCF6.16, 194 aa; fasta scores:
                     opt: 419 Z-score: 483.9 bits: 96.4 E(): 2.3e-19; 38.095%
                     identity in 189 aa overlap. Contains Pfam match to entry
                     PF00440 tetR, Bacterial regulatory proteins, tetR family
                     and possible helix-turn-helix motif at residues 36..57
                     (+4.64 SD)"
                     /product="TetR family transcriptional regulator"
                     /protein_id="NP_629219.1"
                     /transl_table=11
                     /translation="MSWENPGPPKRADARRNYDRIIEAAAAEVARHGADASLEEIARRA
                     GVGSATLHRHFPSRWGLLQAVFQERVAQLCDEARSLAAEHPPATALTRWLTSLAVFGAV
                     TRGAARSLLPATGTNTGAALDSRCEQLLTEAGADLLARAQEDGTVRDDVTALELLSLAN
                     AVSLAAEHTPDAAHHATRLMGIALGGLGAPGPRPQG"
     misc_feature    complement(16118..16255)
                     /gene_synonym="SCBAC20F6.11c"
                     /locus_tag="SCO5068"
                     /note="Pfam match to entry PF00440 tetR, Bacterial
                     regulatory proteins, tetR family, score 52.60, E-value
                     5.2e-12"
     PFAM_domain     complement(16118..16255)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00440.26"
                     /db_xref="GO:0003677"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5068_0418"
                     /evalue="4.10E-12"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /label="SCO5068"
                     /locus_tag="SCO5068"
                     /protein_end="66"
                     /protein_start="20"
                     /score="45.8"
                     /tool="antismash"
                     /translation="IIEAAAAEVARHGADASLEEIARRAGVGSATLHRHFPSRWGLLQA
                     V"
     gene            16471..17427
                     /db_xref="GeneID:1100510"
                     /gene_synonym="SCBAC20F6.12"
                     /locus_tag="SCO5069"
     CDS             16471..17427
                     /NRPS_PKS="Domain: PKS_ER (14-313). E-value: 1.1e-39.
                     Score: 128.3. Matches aSDomain:
                     nrpspksdomains_SCO5069_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:1100510"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCBAC20F6.12"
                     /locus_tag="SCO5069"
                     /note="SCBAC20F6.12, possible oxidoreductase, len: 318 aa;
                     similar to many oxidoreductases/dehydratases, e.g.
                     TR:Q9WX20 (EMBL:AL079345) Streptomyces coelicolor
                     dehydrogenase SCE68.12c, 318 aa; fasta scores: opt: 998
                     Z-score: 1062.9 bits: 204.9 E(): 1.3e-51; 52.997% identity
                     in 317 aa overlap. Contains Pfam match to entry PF00107
                     adh_zinc, Zinc-binding dehydrogenases"
                     /product="oxidoreductase"
                     /protein_id="NP_629220.1"
                     /sec_met_domain="ADH_N (E-value: 9.6e-06, bitscore: 24.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1e-09, bitscore:
                     37.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVQFDRFGPPDVLRVNDVPAPRPGPGEVLVEVRAASVDAGETA
                     FRAGRMRRVTRVRFPRGLGSDFAGRVAALGSGVRAWSVGDAVWGLMPHLTFGAIADYVA
                     VPEQRLARAPQNLDLLEAAALPVVGTTAMTALSGKARLQPGERLLVRGATGGVGSVAVQ
                     LGKALGAHVTALAAARNLDWITRLGADEAVDYRTTRPEDLDRFDVIVDVVGTDLGAYRK
                     RLARGGRLVALSFDSDRVVSSMLGIALRAAATPRRVKMFSNNPSADRIAELTRAVEAGT
                     IRPVVDTVFPMRDIAAVHQRLEAGGVRGKYVVDLRLP"
     misc_feature    16510..17415
                     /gene_synonym="SCBAC20F6.12"
                     /locus_tag="SCO5069"
                     /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases, score 182.30, E-value 8e-51"
     aSDomain        16513..17409
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5069_PKS_ER.1"
                     /evalue="1.10E-39"
                     /label="SCO5069_PKS_ER.1"
                     /locus_tag="SCO5069"
                     /protein_end="313"
                     /protein_start="14"
                     /score="128.3"
                     /tool="antismash"
                     /translation="LRVNDVPAPRPGPGEVLVEVRAASVDAGETAFRAGRMRRVTRVRF
                     PRGLGSDFAGRVAALGSGVRAWSVGDAVWGLMPHLTFGAIADYVAVPEQRLARAPQNLD
                     LLEAAALPVVGTTAMTALSGKARLQPGERLLVRGATGGVGSVAVQLGKALGAHVTALAA
                     ARNLDWITRLGADEAVDYRTTRPEDLDRFDVIVDVVGTDLGAYRKRLARGGRLVALSFD
                     SDRVVSSMLGIALRAAATPRRVKMFSNNPSADRIAELTRAVEAGTIRPVVDTVFPMRDI
                     AAVHQRLEAGGVRGKYVV"
     CDS_motif       16903..16962
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5069_0001"
                     /evalue="2.80E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="SCO5069"
                     /protein_end="164"
                     /protein_start="144"
                     /score="16.7"
                     /tool="antismash"
                     /translation="GERLLVRGATGGVGSVAVQL"
     PFAM_domain     17029..17409
                     /aSDomain="ADH_zinc_N_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13602.9"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5069_0419"
                     /evalue="3.00E-22"
                     /label="SCO5069"
                     /locus_tag="SCO5069"
                     /protein_end="313"
                     /protein_start="186"
                     /score="80.2"
                     /tool="antismash"
                     /translation="LGADEAVDYRTTRPEDLDRFDVIVDVVGTDLGAYRKRLARGGRLV
                     ALSFDSDRVVSSMLGIALRAAATPRRVKMFSNNPSADRIAELTRAVEAGTIRPVVDTVF
                     PMRDIAAVHQRLEAGGVRGKYVV"
     misc_feature    17441..22686
                     /note="previously sequenced DNA fragment. EMBL:X62373
                     S.coelicolor genes for hydroxyacyl-CoA dehydrogenase"
     gene            complement(17468..18652)
                     /db_xref="GeneID:1100511"
                     /gene_synonym="SCBAC20F6.13c"
                     /locus_tag="SCO5070"
     CDS             complement(17468..18652)
                     /codon_start=1
                     /db_xref="GeneID:1100511"
                     /gene_synonym="SCBAC20F6.13c"
                     /locus_tag="SCO5070"
                     /note="SCBAC20F6.13c, ORFB hydroxylacyl-CoA dehydrogenase,
                     len: 394 aa; identical to previously sequenced TR:Q53924
                     (EMBL:X62373) Streptomyces coelicolor hydroxylacyl-CoA
                     dehydrogenase ORFB, 394 aa. There is an alternative start
                     codon 120 base pairs upstream of the previously sequenced
                     one"
                     /product="hydroxylacyl-CoA dehydrogenase"
                     /protein_id="NP_629221.1"
                     /transl_table=11
                     /translation="MLSVGHGPRHVLVVARPHPDEPVGGATALALAELVAGGDRRSPAT
                     DPEAVTWDIVLCLDPDGAALSEGIETATAGPAPSLASYYRAAFRPVAAEQPEWAPIVGR
                     PLPESRALFDVIDDLRPVLQCSLHNVDAGGTWAQLTRDLPGLAAPFAASAAALGVPVQH
                     GTYDALYWENPAPGIHVLPPPGSTARPAAGSEDIGLSTWCAPQRYGGATAIVEVPLWAT
                     APADDPTPHADPARALRALSGLVREGGRQVTAVFERARGLLPAPEDSPPVRVLEWMAED
                     LYDLVADSWGPLVRQAEAGPRTDGSPALTTAGIGALEVVARRQPLRAAGLLLRLLHAAD
                     APAAAGLHHELDALFTAWCTDFETSLRLRWVPVHAQVELQARTVVAAAECALTP"
     misc_feature    18908..18920
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     misc_feature    18935..18949
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            complement(19009..19449)
                     /db_xref="GeneID:1100512"
                     /gene_synonym="SCBAC20F6.14c"
                     /locus_tag="SCO5071"
     CDS             complement(19009..19449)
                     /codon_start=1
                     /db_xref="GeneID:1100512"
                     /gene_synonym="SCBAC20F6.14c"
                     /locus_tag="SCO5071"
                     /note="SCBAC20F6.14c, ORFA hydroxylacyl-CoA dehydrogenase,
                     len: 146 aa; identical to previously sequenced TR:Q53925
                     (EMBL:X62373) Streptomyces coelicolor hydroxylacyl-CoA
                     dehydrogenase ORFA, 146 aa"
                     /product="hydroxylacyl-CoA dehydrogenase"
                     /protein_id="NP_629222.1"
                     /transl_table=11
                     /translation="MTITALPTGLYAEVLSFYGHQMQKLDGRDFAGYAATFTEDGEFRH
                     SPSLPAAHTRAGITAVLEDFHRKFDARKIQRRHWFDHTALSQASDGSITATSYCLVLTV
                     HADVKAPEFGPSCLVHDVLVRGADGELLLRSRHVTHDHVFPA"
     PFAM_domain     complement(19063..19416)
                     /aSDomain="SnoaL_4"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13577.9"
                     /description="SnoaL-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5071_0420"
                     /evalue="6.70E-09"
                     /label="SCO5071"
                     /locus_tag="SCO5071"
                     /protein_end="129"
                     /protein_start="11"
                     /score="36.0"
                     /tool="antismash"
                     /translation="AEVLSFYGHQMQKLDGRDFAGYAATFTEDGEFRHSPSLPAAHTRA
                     GITAVLEDFHRKFDARKIQRRHWFDHTALSQASDGSITATSYCLVLTVHADVKAPEFGP
                     SCLVHDVLVRGADG"
     misc_feature    19523..20041
                     /gene_synonym="SCBAC20F6.15"
                     /locus_tag="SCO5072"
                     /note="Pfam match to entry PF02737 3HCDH_N,
                     3-hydroxyacyl-CoA dehydrogenase, NAD binding domain, score
                     78.20, E-value 1.7e-19"
     gene            19523..20446
                     /db_xref="GeneID:1100513"
                     /gene_synonym="SCBAC20F6.15"
                     /locus_tag="SCO5072"
     CDS             19523..20446
                     /codon_start=1
                     /db_xref="GeneID:1100513"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     159.4; E-value: 3.1e-49)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCBAC20F6.15"
                     /locus_tag="SCO5072"
                     /note="SCBAC20F6.15, ORF1 hydroxylacyl-CoA dehydrogenase,
                     len: 307 aa; identical to previously sequenced TR:Q53926
                     (EMBL:X62373) Streptomyces coelicolor hydroxylacyl-CoA
                     dehydrogenase ORF1, 307 aa. Contains Pfam matches to
                     entries PF02737 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase,
                     NAD binding domain and PF00725 3HCDH, 3-hydroxyacyl-CoA
                     dehydrogenase, C-terminal domain. Contains possible
                     hydrophobic membrane spanning region"
                     /product="hydroxylacyl-CoA dehydrogenase"
                     /protein_id="NP_629223.1"
                     /transl_table=11
                     /translation="MSTVTVIGAGTIGLGWINLFSARGLTVRVNSRRPDVRRVVHEALE
                     LFSPGRVDELAARIEYEPDVGRAVAGADVVSENAPDDLPLKQRLFAEIGAAAPDHALVL
                     SSTSKLLPDELSRDMPGPGRLVVAHPFNPPHIVPLVEVVRGERTDPEAVERTLAFLASV
                     GRTPVVVRRALPGFAANRLQSALLRESIHLVLEGVVTVEELDRIVTDSIGLRWSTIGPF
                     HAFHLGGGPGGLRKWLEHLGSGLEQGWRGLGQPALTPQAVEALVAQTEAAYGHRPYAEL
                     VRDRDDRHLAVLAALERTEQPQEETK"
     PFAM_domain     19529..20035
                     /aSDomain="3HCDH_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02737.21"
                     /db_xref="GO:0006631"
                     /db_xref="GO:0070403"
                     /description="3-hydroxyacyl-CoA dehydrogenase, NAD binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5072_0421"
                     /evalue="7.40E-44"
                     /gene_ontologies="GO:0006631: fatty acid metabolic process"
                     /gene_ontologies="GO:0070403: NAD+ binding"
                     /label="SCO5072"
                     /locus_tag="SCO5072"
                     /protein_end="171"
                     /protein_start="2"
                     /score="149.9"
                     /tool="antismash"
                     /translation="TVTVIGAGTIGLGWINLFSARGLTVRVNSRRPDVRRVVHEALELF
                     SPGRVDELAARIEYEPDVGRAVAGADVVSENAPDDLPLKQRLFAEIGAAAPDHALVLSS
                     TSKLLPDELSRDMPGPGRLVVAHPFNPPHIVPLVEVVRGERTDPEAVERTLAFLASVGR
                     TPVVVR"
     PFAM_domain     20048..20314
                     /aSDomain="3HCDH"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00725.25"
                     /db_xref="GO:0006631"
                     /db_xref="GO:0016491"
                     /db_xref="GO:0016616"
                     /description="3-hydroxyacyl-CoA dehydrogenase, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5072_0422"
                     /evalue="5.10E-13"
                     /gene_ontologies="GO:0006631: fatty acid metabolic process"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /gene_ontologies="GO:0016616: oxidoreductase activity,
                     acting on the CH-OH group of donors, NAD or NADP as
                     acceptor"
                     /label="SCO5072"
                     /locus_tag="SCO5072"
                     /protein_end="264"
                     /protein_start="175"
                     /score="49.5"
                     /tool="antismash"
                     /translation="GFAANRLQSALLRESIHLVLEGVVTVEELDRIVTDSIGLRWSTIG
                     PFHAFHLGGGPGGLRKWLEHLGSGLEQGWRGLGQPALTPQAVEA"
     misc_feature    20048..20356
                     /gene_synonym="SCBAC20F6.15"
                     /locus_tag="SCO5072"
                     /note="Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA
                     dehydrogenase, C-terminal domain, score -8.40, E-value
                     0.048"
     regulatory      20433..20437
                     /gene_synonym="SCBAC20F6.15"
                     /locus_tag="SCO5072"
                     /regulatory_class="ribosome_binding_site"
     gene            20443..21432
                     /db_xref="GeneID:1100514"
                     /gene_synonym="SCBAC20F6.16"
                     /locus_tag="SCO5073"
     CDS             20443..21432
                     /NRPS_PKS="Domain: PKS_ER (15-327). E-value: 3.2e-54.
                     Score: 176.1. Matches aSDomain:
                     nrpspksdomains_SCO5073_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:1100514"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCBAC20F6.16"
                     /locus_tag="SCO5073"
                     /note="SCBAC20F6.16, ORF2, possible oxidoreductase, len:
                     329 aa; identical to previously sequenced TR:Q53927
                     (EMBL:X62373) Streptomyces coelicolor genes for
                     hydroxylacyl-CoA dehydrogenase ORF2, 329 aa. Contains Pfam
                     match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases and match to Prosite entry PS01162 Quinone
                     oxidoreductase / zeta-crystallin signature"
                     /product="oxidoreductase"
                     /protein_id="NP_629224.1"
                     /sec_met_domain="ADH_N (E-value: 8.2e-07, bitscore: 27.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.1e-27, bitscore:
                     92.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMRAVQFDRYGDPDVLYVAERPVPEPGPGQVRIAVDAVSVGHAQT
                     QMRREAFPAPMWRPVFPVVLGGDVVGRITAVGPGVTALRPGDRVGAFTLYGAYAEQVVV
                     DAVTVVPVPEELDAAEAAVLPGTGLIALGILRTGRLRKGETVLIHAAAGGVGHIAVQLA
                     RAAGAGLIIGTAGAAAKREFARATGADAVVDHRSAHWADEVRELTGGRGPDLILDGIGA
                     EVLEQGVGLLAPGGRLVFYGSSGGELAIPKVSVMDLIGIKYVTGFALSAWRGGRPQEYE
                     AGVAELTRLLAEGQVTSAVHARLPLERAAEAHAVVEARAQLGRVVLVP"
     misc_feature    20485..21429
                     /gene_synonym="SCBAC20F6.16"
                     /locus_tag="SCO5073"
                     /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases, score 276.60, E-value 3.3e-79"
     aSDomain        20488..21423
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5073_PKS_ER.1"
                     /evalue="3.20E-54"
                     /label="SCO5073_PKS_ER.1"
                     /locus_tag="SCO5073"
                     /protein_end="327"
                     /protein_start="15"
                     /score="176.1"
                     /tool="antismash"
                     /translation="LYVAERPVPEPGPGQVRIAVDAVSVGHAQTQMRREAFPAPMWRPV
                     FPVVLGGDVVGRITAVGPGVTALRPGDRVGAFTLYGAYAEQVVVDAVTVVPVPEELDAA
                     EAAVLPGTGLIALGILRTGRLRKGETVLIHAAAGGVGHIAVQLARAAGAGLIIGTAGAA
                     AKREFARATGADAVVDHRSAHWADEVRELTGGRGPDLILDGIGAEVLEQGVGLLAPGGR
                     LVFYGSSGGELAIPKVSVMDLIGIKYVTGFALSAWRGGRPQEYEAGVAELTRLLAEGQV
                     TSAVHARLPLERAAEAHAVVEARAQLGRVVL"
     CDS_motif       20869..20931
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5073_0001"
                     /evalue="7.50E-09"
                     /label="PKSI-ER_m5"
                     /locus_tag="SCO5073"
                     /protein_end="163"
                     /protein_start="142"
                     /score="27.9"
                     /tool="antismash"
                     /translation="GETVLIHAAAGGVGHIAVQLA"
     misc_feature    20869..20934
                     /gene_synonym="SCBAC20F6.16"
                     /locus_tag="SCO5073"
                     /note="PS01162 Quinone oxidoreductase / zeta-crystallin
                     signature"
     PFAM_domain     20902..21288
                     /aSDomain="ADH_zinc_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00107.29"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5073_0423"
                     /evalue="2.00E-26"
                     /label="SCO5073"
                     /locus_tag="SCO5073"
                     /protein_end="282"
                     /protein_start="153"
                     /score="92.6"
                     /tool="antismash"
                     /translation="GVGHIAVQLARAAGAGLIIGTAGAAAKREFARATGADAVVDHRSA
                     HWADEVRELTGGRGPDLILDGIGAEVLEQGVGLLAPGGRLVFYGSSGGELAIPKVSVMD
                     LIGIKYVTGFALSAWRGGRPQEYEA"
     regulatory      21485..21490
                     /regulatory_class="ribosome_binding_site"
     gene            21499..22143
                     /db_xref="GeneID:1100515"
                     /gene_synonym="SCBAC20F6.17"
                     /locus_tag="SCO5074"
     CDS             21499..22143
                     /codon_start=1
                     /db_xref="GeneID:1100515"
                     /gene_synonym="SCBAC20F6.17"
                     /locus_tag="SCO5074"
                     /note="SCBAC20F6.17, possible dehydratase, len: 214 aa;
                     identical to previously sequenced TR:Q53928 (EMBL:X62373)
                     Streptomyces coelicolor ORF 3, 214 aa. Similar to TR:Q56172
                     (EMBL:L37334) dehydratase from granaticin biosynthesis
                     cluster of Streptomyces violaceoruber Tu22 (221 aa) fasta
                     scores; opt: 349, Z-score: 400.9, E(): 1.1e-14, 35.465%
                     identity (37.195% ungapped) in 172 aa overlap."
                     /product="dehydratase"
                     /protein_id="NP_629225.1"
                     /transl_table=11
                     /translation="MTSSLHHAIRLTTASAIALGGLVTLGTSAHAASVAVPYECRTWVQ
                     GNTHPVYDYARGFDVSVPASVRAGKKFKATYDPDPITAFAEYNQIVNDVRIAYRIPDGA
                     KVHKVRLTGGSGLGDSDVRVQVKGRDIVVSASGPFQGGVEFDLPTLKVTYKAPKTTGPL
                     NFVSGGSGYEDPGFYWYRYQPILDEWGPFECFPDPAKPEAVLASTQVKKHK"
     regulatory      22168..22171
                     /regulatory_class="ribosome_binding_site"
     gene            22177..23097
                     /db_xref="GeneID:1100516"
                     /gene_synonym="ORF4; SCBAC20F6.18; SCBAC28G1.01"
                     /locus_tag="SCO5075"
     CDS             22177..23097
                     /NRPS_PKS="Domain: PKS_ER (19-251). E-value: 1.2e-34.
                     Score: 111.8. Matches aSDomain:
                     nrpspksdomains_SCO5075_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:1100516"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="ORF4; SCBAC20F6.18; SCBAC28G1.01"
                     /locus_tag="SCO5075"
                     /note="SCBAC28G1.01, possible oxidoreductase, previously
                     sequenced as ORF4, len: 167 aa; identical to C-terminal
                     region of previously sequenced TR:Q53929 (EMBL:X62373)
                     Streptomyces coelicolor ORF4, 306 aa; fasta scores: opt:
                     1029 Z-score: 1146.7 bits: 219.4 E(): 2.9e-56; 95.808%
                     identity in 167 aa overlap. Contains match to Prosite entry
                     PS01162 Quinone oxidoreductase / zeta-crystallin signature;
                     SCBAC20F6.18, ORF4, possible oxidoreductase, len: 170 aa;
                     identical to N-terminal region of the previously sequenced
                     TR:Q53929 (EMBL:X62373) Streptomyces coelicolor ORF 4, 306
                     aa. Contains match to Prosite entry PS01162 Quinone
                     oxidoreductase / zeta-crystallin signature"
                     /product="oxidoreductase"
                     /protein_id="NP_733654.1"
                     /sec_met_domain="ADH_N (E-value: 7.9e-12, bitscore: 43.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.1e-11, bitscore:
                     41.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKAVAIHQFGGPDVLGLVDVPEPVPGPGQVTVRVRAAGVNGFDC
                     RVRSGGMRGRYPVEFPQIIGNEFAGVVERTGPEATGFAPGDEVLGFAVLQSGTELLAVG
                     ADQITVKPPELSWEVAGSLSAVGQTADIALAELRVGPGDTVLVHAAAGGVGSLAVQLVR
                     ERGGTAIGSAGEHNHDYLRSLGALPVAYGPGFADRVRALAPNGVDAALDCHGGPEALAV
                     SLELVADRARIATVANFRAAAQEGIVMPRVVRSAERLAALAALCAEGRLRPHVEAVLPF
                     AKAAEAHHRLEQGHVRGKLVLVPDL"
     aSDomain        22234..22929
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5075_PKS_ER.1"
                     /evalue="1.20E-34"
                     /label="SCO5075_PKS_ER.1"
                     /locus_tag="SCO5075"
                     /protein_end="251"
                     /protein_start="19"
                     /score="111.8"
                     /tool="antismash"
                     /translation="DVPEPVPGPGQVTVRVRAAGVNGFDCRVRSGGMRGRYPVEFPQII
                     GNEFAGVVERTGPEATGFAPGDEVLGFAVLQSGTELLAVGADQITVKPPELSWEVAGSL
                     SAVGQTADIALAELRVGPGDTVLVHAAAGGVGSLAVQLVRERGGTAIGSAGEHNHDYLR
                     SLGALPVAYGPGFADRVRALAPNGVDAALDCHGGPEALAVSLELVADRARIATVANFRA
                     AAQEGIVMPR"
     PFAM_domain     22258..22458
                     /aSDomain="ADH_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08240.15"
                     /description="Alcohol dehydrogenase GroES-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5075_0424"
                     /evalue="2.00E-11"
                     /label="SCO5075"
                     /locus_tag="SCO5075"
                     /protein_end="94"
                     /protein_start="27"
                     /score="43.9"
                     /tool="antismash"
                     /translation="PGQVTVRVRAAGVNGFDCRVRSGGMRGRYPVEFPQIIGNEFAGVV
                     ERTGPEATGFAPGDEVLGFAVL"
     CDS_motif       22366..22404
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5075_0001"
                     /evalue="3.80E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="SCO5075"
                     /protein_end="76"
                     /protein_start="63"
                     /score="10.3"
                     /tool="antismash"
                     /translation="IGNEFAGVVERTG"
     CDS_motif       22525..22557
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5075_0002"
                     /evalue="9.70E+00"
                     /label="PKSI-ER_m2"
                     /locus_tag="SCO5075"
                     /protein_end="127"
                     /protein_start="116"
                     /score="0.1"
                     /tool="antismash"
                     /translation="WEVAGSLSAVG"
     misc_feature    22594..23110
                     /note="previously sequenced DNA fragment. EMBL:X62373
                     S.coelicolor genes for hydroxyacyl-CoA dehydrogenase"
     CDS_motif       22600..22659
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5075_0003"
                     /evalue="4.80E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="SCO5075"
                     /protein_end="161"
                     /protein_start="141"
                     /score="25.4"
                     /tool="antismash"
                     /translation="GDTVLVHAAAGGVGSLAVQL"
     misc_feature    22600..22665
                     /gene_synonym="ORF4; SCBAC20F6.18; SCBAC28G1.01"
                     /locus_tag="SCO5075"
                     /note="PS01162 Quinone oxidoreductase / zeta-crystallin
                     signature"
     PFAM_domain     22765..23082
                     /aSDomain="ADH_zinc_N_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13602.9"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5075_0425"
                     /evalue="1.50E-20"
                     /label="SCO5075"
                     /locus_tag="SCO5075"
                     /protein_end="302"
                     /protein_start="196"
                     /score="74.7"
                     /tool="antismash"
                     /translation="DRVRALAPNGVDAALDCHGGPEALAVSLELVADRARIATVANFRA
                     AAQEGIVMPRVVRSAERLAALAALCAEGRLRPHVEAVLPFAKAAEAHHRLEQGHVRGKL
                     VL"
     misc_feature    23076..28475
                     /note="previously sequenced DNA fragment. EMBL:X58833.1
                     S.coelicolor 6 actVA region genes of the actinorhodin
                     biosynthetic gene cluster"
     gene            23094..24695
                     /db_xref="GeneID:1100517"
                     /gene_synonym="actVA1; SCBAC28G1.02"
                     /locus_tag="SCO5076"
     CDS             23094..24695
                     /codon_start=1
                     /db_xref="GeneID:1100517"
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /gene_synonym="actVA1; SCBAC28G1.02"
                     /locus_tag="SCO5076"
                     /note="SCBAC28G1.02, actVA1, probable integral membrane
                     protein, len: 533 aa; identical to previously sequenced
                     TR:Q53903 (EMBL:X58833) Streptomyces coelicolor 6 ActVA
                     region genes of the actinorhodin biosynthetic gene cluster,
                     ActVA1, 533 aa. Contains possible hydrophobic membrane
                     spanning regions"
                     /product="hypothetical protein"
                     /protein_id="NP_629226.1"
                     /transl_table=11
                     /translation="MTANPGRPGGPADQGHPRRWAILGVLVLSLVGIILDNTVLNVTLR
                     TLTDPEQGLGASHSQVEWVLSAYTLAFAATLFTWGVLGDRLGRRRVLLLGLGLFGLSSL
                     AGAYAGSPEQLIAARACMGVSGAAVLPSTLATIAAVFPLRERPKALGIWAASVGFALGI
                     GPVTGGILLAHFWWGSVLLVNVPLMAGCLVAVVLVVPETRGTAGRRVDAAGLLLSIAGV
                     VPLVYAIIEAGRSGGVTRPAVWAAGLAGLGLLLVFLWHERRTPEPSLELGFFRMKAFST
                     AVAAVGFVSFAMMGFLFFSAFYLQSVRGYTPLQAGGCTVALAVANVVCGPLSTVLVRSI
                     GPRNVCAAGMLAVTASLCGVTFVTQHAPVWLILVLFAALGAGVACVMPTAAVSIMNAIP
                     REKAGVASAMNNTVRQLGGALGVAVLGSLMGAAYRRGIEDELAVLPPSARHQAGESLDA
                     TLLAATRLGESGLVGPARQAFLDAMHLAAGAAAAVALVGALAVLRWLPSSVTTPTPPAG
                     AVPGREHSDHLKVQGS"
     PFAM_domain     23175..24356
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07690.19"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5076_0426"
                     /evalue="6.10E-54"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO5076"
                     /locus_tag="SCO5076"
                     /protein_end="421"
                     /protein_start="27"
                     /score="183.4"
                     /tool="antismash"
                     /translation="LSLVGIILDNTVLNVTLRTLTDPEQGLGASHSQVEWVLSAYTLAF
                     AATLFTWGVLGDRLGRRRVLLLGLGLFGLSSLAGAYAGSPEQLIAARACMGVSGAAVLP
                     STLATIAAVFPLRERPKALGIWAASVGFALGIGPVTGGILLAHFWWGSVLLVNVPLMAG
                     CLVAVVLVVPETRGTAGRRVDAAGLLLSIAGVVPLVYAIIEAGRSGGVTRPAVWAAGLA
                     GLGLLLVFLWHERRTPEPSLELGFFRMKAFSTAVAAVGFVSFAMMGFLFFSAFYLQSVR
                     GYTPLQAGGCTVALAVANVVCGPLSTVLVRSIGPRNVCAAGMLAVTASLCGVTFVTQHA
                     PVWLILVLFAALGAGVACVMPTAAVSIMNAIPREKAGVASAMNNTVRQLGGALG"
     regulatory      24685..24689
                     /gene_synonym="actVA1; SCBAC28G1.02"
                     /locus_tag="SCO5076"
                     /regulatory_class="ribosome_binding_site"
     gene            24697..25092
                     /db_xref="GeneID:1100518"
                     /gene_synonym="actVA2; SCBAC28G1.03"
                     /locus_tag="SCO5077"
     CDS             24697..25092
                     /codon_start=1
                     /db_xref="GeneID:1100518"
                     /gene_synonym="actVA2; SCBAC28G1.03"
                     /locus_tag="SCO5077"
                     /note="SCBAC28G1.03, actVA2, hypothetical protein, len: 131
                     aa; identical to previously sequenced TR:Q53904
                     (EMBL:X58833) Streptomyces coelicolor 6 ActVA region genes
                     of the actinorhodin biosynthetic gene cluster, ActVA2, 131
                     aa"
                     /product="hypothetical protein"
                     /protein_id="NP_629227.1"
                     /transl_table=11
                     /translation="MPFTPDELEYYASQNLGRLATVAPDGQPQANPVSFRVNTETGTID
                     IGGHNLTASKKFRNVTKHDQVAFVVDDLISTQPWNVRGIEVRGRAEALTDAQPPHPYFG
                     TAMIRIHPKRIITWGLGGDAAQRGRDV"
     aSDomain        24703..25056
                     /aSDomain="TIGR04023"
                     /aSTool="tigrfam"
                     /description="PPOX_MSMEG_5819: PPOX class F420-dependent
                     enzyme, MSMEG_5819/OxyR family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5077_0050"
                     /evalue="2.50E-52"
                     /identifier="TIGR04023"
                     /label="SCO5077"
                     /locus_tag="SCO5077"
                     /protein_end="120"
                     /protein_start="2"
                     /score="173.7"
                     /tool="antismash"
                     /translation="FTPDELEYYASQNLGRLATVAPDGQPQANPVSFRVNTETGTIDIG
                     GHNLTASKKFRNVTKHDQVAFVVDDLISTQPWNVRGIEVRGRAEALTDAQPPHPYFGTA
                     MIRIHPKRIITWGL"
     PFAM_domain     24706..24984
                     /aSDomain="Putative_PNPOx"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01243.23"
                     /description="Pyridoxamine 5'-phosphate oxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5077_0427"
                     /evalue="5.90E-16"
                     /label="SCO5077"
                     /locus_tag="SCO5077"
                     /protein_end="96"
                     /protein_start="3"
                     /score="58.5"
                     /tool="antismash"
                     /translation="TPDELEYYASQNLGRLATVAPDGQPQANPVSFRVNTETGTIDIGG
                     HNLTASKKFRNVTKHDQVAFVVDDLISTQPWNVRGIEVRGRAEALTDA"
     regulatory      25174..25178
                     /regulatory_class="ribosome_binding_site"
     gene            25187..26032
                     /db_xref="GeneID:1100519"
                     /gene_synonym="actVA3; SCBAC28G1.04"
                     /locus_tag="SCO5078"
     CDS             25187..26032
                     /codon_start=1
                     /db_xref="GeneID:1100519"
                     /gene_synonym="actVA3; SCBAC28G1.04"
                     /locus_tag="SCO5078"
                     /note="SCBAC28G1.04, actVA3, hypothetical protein, len: 281
                     aa; identical to previously sequenced TR:Q53905
                     (EMBL:X58833) Streptomyces coelicolor 6 ActVA region genes
                     of the actinorhodin biosynthetic gene cluster, ActVA3, 281
                     aa"
                     /product="hypothetical protein"
                     /protein_id="NP_629228.1"
                     /transl_table=11
                     /translation="MSTEIFHEEFAGGLVTEGPGAPWRLRPVDGLEAGDGLVRGGPDGL
                     VVVPSAAHPGTRRPAFTEPKPGPDGTPLHLRWGAFTTGGTTGGTAGARAAFTAVPGERL
                     SVRAEMGLRGFGLRSHPYDDVTEPDADARLGAGGLISVDLESGIIFDFFLTHSRLYAVY
                     ERLALRPDAEFAAFTYCVPVADRTPGTLHRLEVGYDVAAGTAHWTADGQEVLSVDRIGF
                     RALDARWLRRDNGGREEAVRPRGLSFGLGLFLERHFGQGVRLSVRRLSVLTSPAGSRDS
                     "
     PFAM_domain     25205..26008
                     /aSDomain="DUF6081"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19559.2"
                     /description="Family of unknown function (DUF6081)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5078_0428"
                     /evalue="3.70E-90"
                     /label="SCO5078"
                     /locus_tag="SCO5078"
                     /protein_end="274"
                     /protein_start="6"
                     /score="302.0"
                     /tool="antismash"
                     /translation="HEEFAGGLVTEGPGAPWRLRPVDGLEAGDGLVRGGPDGLVVVPSA
                     AHPGTRRPAFTEPKPGPDGTPLHLRWGAFTTGGTTGGTAGARAAFTAVPGERLSVRAEM
                     GLRGFGLRSHPYDDVTEPDADARLGAGGLISVDLESGIIFDFFLTHSRLYAVYERLALR
                     PDAEFAAFTYCVPVADRTPGTLHRLEVGYDVAAGTAHWTADGQEVLSVDRIGFRALDAR
                     WLRRDNGGREEAVRPRGLSFGLGLFLERHFGQGVRLSVRRLSVLTS"
     regulatory      26044..26049
                     /regulatory_class="ribosome_binding_site"
     gene            26057..26941
                     /db_xref="GeneID:1100520"
                     /gene_synonym="actVA4; SCBAC28G1.05"
                     /locus_tag="SCO5079"
     CDS             26057..26941
                     /codon_start=1
                     /db_xref="GeneID:1100520"
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_functions="biosynthetic-additional (t2pks) DIMER
                     (Score: 426.8; E-value: 8.7e-131)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="actVA4; SCBAC28G1.05"
                     /locus_tag="SCO5079"
                     /note="SCBAC28G1.05, actVA4, conserved hypothetical
                     protein, len: 294 aa; identical to previously sequenced
                     TR:Q53906 (EMBL:X58833) Streptomyces coelicolor 6 ActVA
                     region genes of the actinorhodin biosynthetic gene cluster,
                     ActVA4, 294 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_629229.1"
                     /transl_table=11
                     /translation="MPDENKPVLVLGATGKQGGSAARYLLERGWTVRAFVRDPGAPKAK
                     ELRELGASLHTGDLEDAGSVRAAMKGAYGVFSIQTPMTPAGVEGEERQGKICADAARDL
                     GVQHYVHSSVGGAERPEGVNWRLSKLAIEQRIQENALRFTFLRPSYFMENLNHDMSPLV
                     MEDGVLTFRRGLGPANTLQMISGPDIGYFAADAFDDPDTFGGAKIELAGDELTGEQIAA
                     AFGRHTGLPARFVSVPIPELHRTGFEWQAISYTWLNGIGYHADIPTLRARFPQLLTLDQ
                     WLARTGWTPRDPA"
     PFAM_domain     26078..26761
                     /aSDomain="NmrA"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05368.16"
                     /description="NmrA-like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5079_0429"
                     /evalue="2.00E-45"
                     /label="SCO5079"
                     /locus_tag="SCO5079"
                     /protein_end="235"
                     /protein_start="7"
                     /score="155.3"
                     /tool="antismash"
                     /translation="VLVLGATGKQGGSAARYLLERGWTVRAFVRDPGAPKAKELRELGA
                     SLHTGDLEDAGSVRAAMKGAYGVFSIQTPMTPAGVEGEERQGKICADAARDLGVQHYVH
                     SSVGGAERPEGVNWRLSKLAIEQRIQENALRFTFLRPSYFMENLNHDMSPLVMEDGVLT
                     FRRGLGPANTLQMISGPDIGYFAADAFDDPDTFGGAKIELAGDELTGEQIAAAFGRHTG
                     LPARFV"
     regulatory      26926..26929
                     /gene_synonym="actVA4; SCBAC28G1.05"
                     /locus_tag="SCO5079"
                     /regulatory_class="ribosome_binding_site"
     gene            26938..28083
                     /db_xref="GeneID:1100521"
                     /gene_synonym="actVA5; SCBAC28G1.06"
                     /locus_tag="SCO5080"
     CDS             26938..28083
                     /codon_start=1
                     /db_xref="GeneID:1100521"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 44.7; E-value: 2.1e-14)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="actVA5; SCBAC28G1.06"
                     /locus_tag="SCO5080"
                     /note="SCBAC28G1.06, actVA5, possible hydrolase, len: 381
                     aa; identical to previously sequenced TR:Q53907
                     (EMBL:X58833) Streptomyces coelicolor 6 ActVA region genes
                     of the actinorhodin biosynthetic gene cluster, ActVA5, 381
                     aa and similar to TR:Q9F0J3 (EMBL:AF218066) Streptomyces
                     arenae hydrolase NcnH, 405 aa; fasta scores: opt: 1391
                     Z-score: 1521.5 bits: 290.3 E(): 3.9e-77; 56.522% identity
                     in 368 aa overlap"
                     /product="hydrolase"
                     /protein_id="NP_629230.1"
                     /transl_table=11
                     /translation="MSEDTMTQERPSLTAHARRIAELAGKRAADAEQQRRLSPDVVDAV
                     LRAGFAAHFVPVAHGGRAATFGELVEPVAVLGEACASTAWYASLTASLGRMAAYLPDEG
                     QAELWSDGPDALIVGALMPLGRAEKTPGGWHVSGTWPFVSVVDHSDWALICAKVGEEPW
                     FFAVPRQEYGIVDSWYPMGMRGTGSNTLVLDGVFVPDARACTRAAIAAGLGPDAEAICH
                     TVPMRAVNGLAFALPMLGAARGAAAVWTSWTAGRLAGPTGQNAVSSQDRVVYEHTLARA
                     TGEIDAAQLLLERVAAVADAGSATGVLVGRGARDCALAAELLTAATDRLFASAGTRAQA
                     QDSPMQRLWRDVHAAGSHIGLQFGPGAALYAGELLRRSNDG"
     PFAM_domain     27634..28023
                     /aSDomain="Acyl-CoA_dh_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08028.14"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5080_0430"
                     /evalue="5.30E-34"
                     /label="SCO5080"
                     /locus_tag="SCO5080"
                     /protein_end="362"
                     /protein_start="232"
                     /score="117.5"
                     /tool="antismash"
                     /translation="AFALPMLGAARGAAAVWTSWTAGRLAGPTGQNAVSSQDRVVYEHT
                     LARATGEIDAAQLLLERVAAVADAGSATGVLVGRGARDCALAAELLTAATDRLFASAGT
                     RAQAQDSPMQRLWRDVHAAGSHIGLQ"
     regulatory      28063..28068
                     /gene_synonym="actVA5; SCBAC28G1.06"
                     /locus_tag="SCO5080"
                     /regulatory_class="ribosome_binding_site"
     gene            28076..28417
                     /db_xref="GeneID:1100522"
                     /gene_synonym="actVA6; SCBAC28G1.07"
                     /locus_tag="SCO5081"
     CDS             28076..28417
                     /codon_start=1
                     /db_xref="GeneID:1100522"
                     /gene_synonym="actVA6; SCBAC28G1.07"
                     /locus_tag="SCO5081"
                     /note="SCBAC28G1.07, actVA6, hypothetical protein, len: 113
                     aa; identical to previously sequenced TR:Q53908
                     (EMBL:X58833) Streptomyces coelicolor 6 ActVA region genes
                     of the actinorhodin biosynthetic gene cluster, ActVA6, 113
                     aa and similar to SW:TCMH_STRGA (EMBL:M80674) Streptomyces
                     glaucescens tetracenomycin polyketide synthesis hydroxylase
                     TcmH, 112 aa; fasta scores: opt: 193 Z-score: 247.6 bits:
                     51.0 E(): 3.5e-06; 43.210% identity in 81 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_629231.1"
                     /transl_table=11
                     /translation="MAEVNDPRVGFVAVVTFPVDGPATQHKLVELATGGVQEWIREVPG
                     FLSATYHASTDGTAVVNYAQWESEQAYRVNFGADPRSAELREALSSLPGLMGPPKAVFM
                     TPRGAILPS"
     PFAM_domain     28109..28294
                     /aSDomain="ABM"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03992.19"
                     /description="Antibiotic biosynthesis monooxygenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5081_0431"
                     /evalue="2.90E-09"
                     /label="SCO5081"
                     /locus_tag="SCO5081"
                     /protein_end="73"
                     /protein_start="11"
                     /score="37.0"
                     /tool="antismash"
                     /translation="VAVVTFPVDGPATQHKLVELATGGVQEWIREVPGFLSATYHASTD
                     GTAVVNYAQWESEQAYR"
     misc_feature    28191..34090
                     /note="previously sequenced DNA fragment. EMBL:M64683
                     Streptomyces coelicolor ORF1-4 (actII) gene, complete cds"
     gene            complement(28383..29162)
                     /db_xref="GeneID:1100523"
                     /gene_synonym="actII-1; SCBAC28G1.08c"
                     /locus_tag="SCO5082"
     CDS             complement(28383..29162)
                     /codon_start=1
                     /db_xref="GeneID:1100523"
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="actII-1; SCBAC28G1.08c"
                     /locus_tag="SCO5082"
                     /note="SCBAC28G1.08c, actII-1, probable transcriptional
                     regulatory protein, len: 259 aa; identical to previously
                     sequenced TR:Q53901 (EMBL:M64683) Streptomyces coelicolor
                     ORF1-4 (ActII), 259 aa. Contains Pfam matches to entries
                     PF00440 tetR, Bacterial regulatory proteins, tetR family
                     and PF02909 tetR_C, Tetracyclin repressor, C-terminal
                     all-alpha domain and possible helix-turn-helix motif at
                     residues 53..73 (+2.78 SD)"
                     /product="transcriptional regulator"
                     /protein_id="NP_629232.1"
                     /transl_table=11
                     /translation="MSRSEEGRPMPEEIPVPPWRRPKKAPPRMPLTQDRIVVTALGILD
                     AEGLDALSMRRLAQELKTGHASLYAHVGNRDELLDLVFDIVLTEVEVPEPEPGRWAEQV
                     KEMCRSLRRMFLAHRDLARIAIDRVPLGPNGMVGMERTMNLLRSGGLHDELAAYGGDLL
                     STFVTAEALEQSSRNPGTEQGREQAGVFADQLHGYLKSLPATSFPNLVHLAGPITSLDS
                     DRRFELGLEIIIAGLLAGAGEAADDQVRTAGSPPAES"
     misc_feature    complement(28440..28883)
                     /gene_synonym="actII-1; SCBAC28G1.08c"
                     /locus_tag="SCO5082"
                     /note="Pfam match to entry PF02909 tetR_C, Tetracyclin
                     repressor, C-terminal all-alpha domain, score 217.30,
                     E-value 2.2e-61"
     PFAM_domain     complement(28446..28880)
                     /aSDomain="TetR_C_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02909.20"
                     /db_xref="GO:0045892"
                     /description="Tetracyclin repressor-like, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5082_0433"
                     /evalue="1.00E-46"
                     /gene_ontologies="GO:0045892: negative regulation of
                     DNA-templated transcription"
                     /label="SCO5082"
                     /locus_tag="SCO5082"
                     /protein_end="239"
                     /protein_start="94"
                     /score="158.4"
                     /tool="antismash"
                     /translation="PEPGRWAEQVKEMCRSLRRMFLAHRDLARIAIDRVPLGPNGMVGM
                     ERTMNLLRSGGLHDELAAYGGDLLSTFVTAEALEQSSRNPGTEQGREQAGVFADQLHGY
                     LKSLPATSFPNLVHLAGPITSLDSDRRFELGLEIIIAGLLA"
     misc_feature    complement(28917..29057)
                     /gene_synonym="actII-1; SCBAC28G1.08c"
                     /locus_tag="SCO5082"
                     /note="Pfam match to entry PF00440 tetR, Bacterial
                     regulatory proteins, tetR family, score 43.50, E-value
                     1.3e-09"
     PFAM_domain     complement(28923..29057)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00440.26"
                     /db_xref="GO:0003677"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5082_0432"
                     /evalue="3.80E-06"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /label="SCO5082"
                     /locus_tag="SCO5082"
                     /protein_end="80"
                     /protein_start="35"
                     /score="26.7"
                     /tool="antismash"
                     /translation="IVVTALGILDAEGLDALSMRRLAQELKTGHASLYAHVGNRDELLD
                     "
     regulatory      complement(29168..29171)
                     /regulatory_class="ribosome_binding_site"
     misc_feature    29195..29204
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.67"
                     /tool="antismash"
     gene            29273..31009
                     /db_xref="GeneID:1100524"
                     /gene_synonym="actII-2; SCBAC28G1.09"
                     /locus_tag="SCO5083"
     CDS             29273..31009
                     /codon_start=1
                     /db_xref="GeneID:1100524"
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /gene_synonym="actII-2; SCBAC28G1.09"
                     /locus_tag="SCO5083"
                     /note="SCBAC28G1.09, actII-2, probable actinorhodin
                     transporter, len: 578 aa; identical to previously sequenced
                     SW:AC22_STRCO (EMBL:M64683) Streptomyces coelicolor
                     probable actinorhodin transporter ActII-2, 578 aa. Contains
                     possible hydrophobic membrane spanning regions and a
                     leucine TTA codon, possible target for bldA regulation"
                     /product="actinorhodin transporter"
                     /protein_id="NP_629233.1"
                     /transl_table=11
                     /translation="MSSVEADEPDRATAPPSALLPEDGPGPDGTAAGPPPYARRWAALG
                     VILGAEIMDLLDGTVMNVAAPAVRADLGGSLSVIQWITVGYTLAFAVLLVVGGRLGDIY
                     GRKRMFVVGAVGFTAASVLCSVAAGPEMLTAARFLQGGLGALMIPQGLGLIKQMFPPKE
                     TAAAFGAFGPAIGLGAVLGPIVAGFLVDADLFGTGWRSVFLINLPIGVAVIVGAVLLLP
                     EGKAPVRPKFDVVGMALVTSGLTLLIFPLVQGRERGWPAWAFVLMLAGAAVLVGFVAHE
                     LRQERRGGATLIELSLLRRSRYAAGLAVALVFFTGVSGMSLLLALHLQIGLGFSPTRAA
                     LTMTPWSVFLVVGAILTGAVLGSKFGRKALHGGLVVLALGVLIMLLTIGDQAGGLTSWE
                     LVPGIAVAGLGMGIMIGLLFDIALADVDKQEAGTASGVLTAVQQLGFTVGVAVLGTLFF
                     GLLGSQATASVDDGASRARTELAAAGASTTEQDRLLADLRVCLRESASQQDSERTPDSC
                     RNLQQARPAVAEATARAWRTAHTENFSTAMVRTLWVVIALLAVSFALAFRLPPKPREEE
                     GF"
     misc_feature    29327..29329
                     /gene_synonym="actII-2; SCBAC28G1.09"
                     /locus_tag="SCO5083"
                     /note="TTA leucine codon; possible target for bldA
                     regulation"
     misc_feature    29327..29329
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     PFAM_domain     29426..30619
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07690.19"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5083_0434"
                     /evalue="1.40E-46"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO5083"
                     /locus_tag="SCO5083"
                     /protein_end="449"
                     /protein_start="51"
                     /score="159.2"
                     /tool="antismash"
                     /translation="IMDLLDGTVMNVAAPAVRADLGGSLSVIQWITVGYTLAFAVLLVV
                     GGRLGDIYGRKRMFVVGAVGFTAASVLCSVAAGPEMLTAARFLQGGLGALMIPQGLGLI
                     KQMFPPKETAAAFGAFGPAIGLGAVLGPIVAGFLVDADLFGTGWRSVFLINLPIGVAVI
                     VGAVLLLPEGKAPVRPKFDVVGMALVTSGLTLLIFPLVQGRERGWPAWAFVLMLAGAAV
                     LVGFVAHELRQERRGGATLIELSLLRRSRYAAGLAVALVFFTGVSGMSLLLALHLQIGL
                     GFSPTRAALTMTPWSVFLVVGAILTGAVLGSKFGRKALHGGLVVLALGVLIMLLTIGDQ
                     AGGLTSWELVPGIAVAGLGMGIMIGLLFDIALADVDKQEAGTASGVLTAVQQLGFTVG"
     gene            31009..33144
                     /db_xref="GeneID:1100525"
                     /gene_synonym="actII-3; SCBAC28G1.10"
                     /locus_tag="SCO5084"
     CDS             31009..33144
                     /codon_start=1
                     /db_xref="GeneID:1100525"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="actII-3; SCBAC28G1.10"
                     /locus_tag="SCO5084"
                     /note="SCBAC28G1.10, actII-3, membrane protein, len: 711
                     aa; identical to previously sequenced SW:MMLA_STRCO
                     (EMBL:M64683) Streptomyces coelicolor membrane protein
                     ActII-3, 711 aa. Contains possible hydrophobic membrane
                     spanning regions"
                     /product="hypothetical protein"
                     /protein_id="NP_629234.1"
                     /transl_table=11
                     /translation="MTRTLLSWPGGRRLKWLVLAAWIGLLIVLQPLAGKLGDVESNDAA
                     AWLPGNAESTEVLELSEKFQPADTSPTVIVYDRPSGITAADEAKARADATHFADGTGVV
                     GEPYGPVRSDDGKALRTVVNVHLGKDGWEGLNAAAKDMRAIARPSAPDGLGVHVTGPTG
                     YAADSAESFSSADFKLTLVTLLIVVTILVVTYRSPLLWLLPMISAGMSLVISQAIVYLL
                     AKNAGLTVNAQTAMILTVLVLGAATDYALLLVARYREELRRHEDRHEAMAVALRRAGPA
                     IVASAATVAVSMLVLLLAALNSTKGLGPVCAVGVLVGLLSMMTLLPALLVIFGRWVFWP
                     ARPKHGTEPDVTRGLWSRIARLVSGRPRAVWVTTSLLLGAVATLAVTLNADGLQQKDGF
                     KTKPESVVGEEILTRHFPAGSGEPMVVIAKGASADQVHAALETVPGVIEVAPPQVKDGL
                     AYVEATLGAGADSPAAMRSVTAARETLARLDGAQARVGGSSAVVHDMREASSRDRGLII
                     PVILAVVFCILALLLRALVAPLLLIASVVLSFFTALGLAALFFNHVFDFAGADSAFPLW
                     VFVFLVALGVDYNIFLVTRIKEESDRLGTRQGALKGLTSTGGVITAAGLVLAGTFAALA
                     TLPLVFIAELGFTVAVGVLLDTMIVRSVLVTALTLDVGRWMWWPHPLARREDPSEDPAV
                     SGMPDSIDSEASTTASR"
     PFAM_domain     31147..32115
                     /aSDomain="MMPL"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03176.18"
                     /db_xref="GO:0016020"
                     /description="MMPL family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5084_0435"
                     /evalue="3.40E-83"
                     /gene_ontologies="GO:0016020: membrane"
                     /label="SCO5084"
                     /locus_tag="SCO5084"
                     /protein_end="369"
                     /protein_start="46"
                     /score="279.5"
                     /tool="antismash"
                     /translation="WLPGNAESTEVLELSEKFQPADTSPTVIVYDRPSGITAADEAKAR
                     ADATHFADGTGVVGEPYGPVRSDDGKALRTVVNVHLGKDGWEGLNAAAKDMRAIARPSA
                     PDGLGVHVTGPTGYAADSAESFSSADFKLTLVTLLIVVTILVVTYRSPLLWLLPMISAG
                     MSLVISQAIVYLLAKNAGLTVNAQTAMILTVLVLGAATDYALLLVARYREELRRHEDRH
                     EAMAVALRRAGPAIVASAATVAVSMLVLLLAALNSTKGLGPVCAVGVLVGLLSMMTLLP
                     ALLVIFGRWVFWPARPKHGTEPDVTRGLWSRIARLVSGRPRA"
     PFAM_domain     32296..33051
                     /aSDomain="MMPL"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03176.18"
                     /db_xref="GO:0016020"
                     /description="MMPL family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5084_0436"
                     /evalue="3.20E-61"
                     /gene_ontologies="GO:0016020: membrane"
                     /label="SCO5084"
                     /locus_tag="SCO5084"
                     /protein_end="681"
                     /protein_start="429"
                     /score="207.3"
                     /tool="antismash"
                     /translation="GASADQVHAALETVPGVIEVAPPQVKDGLAYVEATLGAGADSPAA
                     MRSVTAARETLARLDGAQARVGGSSAVVHDMREASSRDRGLIIPVILAVVFCILALLLR
                     ALVAPLLLIASVVLSFFTALGLAALFFNHVFDFAGADSAFPLWVFVFLVALGVDYNIFL
                     VTRIKEESDRLGTRQGALKGLTSTGGVITAAGLVLAGTFAALATLPLVFIAELGFTVAV
                     GVLLDTMIVRSVLVTALTLDVGRWMWWPHP"
     misc_feature    complement(33151..33160)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     stem_loop       33151..33193
                     /note="possible stem loop. Score 60: 20/20 (100%) matches,
                     0 gaps"
     misc_feature    33157..33162
                     /note="AseI site matched ATTAAT. Divides the AseI-K and the
                     AseI-N genomic restriction fragments; Cleavage site for
                     AseI restriction endonuclease AT*TAAT."
     misc_feature    complement(33157..33162)
                     /note="Cleavage site for AseI restriction endonuclease
                     AT*TAAT."
     misc_feature    33183..33188
                     /note="AseI site matched ATTAAT. Divides the AseI-K and the
                     AseI-N genomic restriction fragments; Cleavage site for
                     AseI restriction endonuclease AT*TAAT."
     misc_feature    complement(33183..33188)
                     /note="Cleavage site for AseI restriction endonuclease
                     AT*TAAT."
     misc_feature    33185..33194
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     misc_feature    33186..33199
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.8"
                     /tool="antismash"
     misc_feature    33187..33200
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.44"
                     /tool="antismash"
     misc_feature    33192..33206
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.83"
                     /tool="antismash"
     misc_feature    complement(33211..33226)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.67"
                     /tool="antismash"
     gene            33294..34061
                     /db_xref="GeneID:1100526"
                     /gene_synonym="actII-4; SCBAC28G1.11"
                     /locus_tag="SCO5085"
     CDS             33294..34061
                     /codon_start=1
                     /db_xref="GeneID:1100526"
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /gene_synonym="actII-4; SCBAC28G1.11"
                     /locus_tag="SCO5085"
                     /note="SCBAC28G1.11, actII-4, actinorhodin cluster
                     activator protein, len: 255 aa; identical to previously
                     sequenced SW:AC24_STRCO (EMBL:M64683) Streptomyces
                     coelicolor actinorhodin operon activator protein ActII-4,
                     255 aa. Contains a leucine TTA codon, possible target for
                     bldA regulation"
                     /product="actinorhodin operon activator protein"
                     /protein_id="NP_629235.1"
                     /transl_table=11
                     /translation="MRFNLLGRVHVITDAGCVIPLKSSKATQLLVLLLLRRHEVVGSGV
                     LIEELWADHPPRSAMTTLQTYVYHTRRLLGEHRVTSDDRELVLTQPPGYFALIDEDELD
                     VAVAERLIRTGGRLLEENRLEEALASLDAGLDLWRGPALSTVPCGRVLESNIAHLEELR
                     LFGMQLRIDANWRLGRIGPMIPELRSLVISHPLNETLHAKLMGALCQMGRRAEALESYR
                     NLRRILSDELGVDPTPEIQRMHMEILNGEKVLV"
     misc_feature    33306..33308
                     /gene_synonym="actII-4; SCBAC28G1.11"
                     /locus_tag="SCO5085"
                     /note="TTA leucine codon; possible target for bldA
                     regulation"
     misc_feature    33306..33308
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     PFAM_domain     33360..33575
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00486.31"
                     /db_xref="GO:0000160"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0006355"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5085_0437"
                     /evalue="6.70E-10"
                     /gene_ontologies="GO:0000160: phosphorelay signal
                     transduction system"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO5085"
                     /locus_tag="SCO5085"
                     /protein_end="94"
                     /protein_start="22"
                     /score="39.0"
                     /tool="antismash"
                     /translation="SSKATQLLVLLLLRRHEVVGSGVLIEELWADHPPRSAMTTLQTYV
                     YHTRRLLGEHRVTSDDRELVLTQPPGY"
     PFAM_domain     33600..34037
                     /aSDomain="BTAD"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03704.20"
                     /description="Bacterial transcriptional activator domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5085_0438"
                     /evalue="9.10E-49"
                     /label="SCO5085"
                     /locus_tag="SCO5085"
                     /protein_end="248"
                     /protein_start="102"
                     /score="165.7"
                     /tool="antismash"
                     /translation="LDVAVAERLIRTGGRLLEENRLEEALASLDAGLDLWRGPALSTVP
                     CGRVLESNIAHLEELRLFGMQLRIDANWRLGRIGPMIPELRSLVISHPLNETLHAKLMG
                     ALCQMGRRAEALESYRNLRRILSDELGVDPTPEIQRMHMEIL"
     misc_feature    complement(33995..35029)
                     /note="previously sequenced DNA fragment. EMBL:M19536
                     S.coelicolor actIII gene, complete cds."
     stem_loop       34064..34128
                     /note="possible stem loop. Score 96: 32/32 (100%) matches,
                     0 gaps"
     gene            complement(34135..34920)
                     /db_xref="GeneID:1100527"
                     /gene_synonym="actIII; SCBAC28G1.12c"
                     /locus_tag="SCO5086"
     CDS             complement(34135..34920)
                     /NRPS_PKS="Domain: PKS_KR (7-126). E-value: 3.5e-12. Score:
                     38.5. Matches aSDomain: nrpspksdomains_SCO5086_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:1100527"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 438.4; E-value: 1.9e-134)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="actIII; SCBAC28G1.12c"
                     /locus_tag="SCO5086"
                     /note="SCBAC28G1.12c, actIII, ketoacyl reductase, len: 261
                     aa; identical to previously sequenced SW:ACT3_STRCO
                     (EMBL:M19536) Streptomyces coelicolor ketoacyl reductase
                     ActIII, 261 aa. Contains Pfam matches to entries PF00106
                     adh_short, short chain dehydrogenase and PF00678
                     adh_short_C2, Short chain dehydrogenase/reductase
                     C-terminus and match to Prosite entry PS00061 Short-chain
                     dehydrogenases/reductases family signature"
                     /product="ketoacyl reductase"
                     /protein_id="NP_629236.1"
                     /sec_met_domain="adh_short (E-value: 3.2e-38, bitscore:
                     130.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQDSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRT
                     TLKELREAGVEADGRTCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELAD
                     ELWLDVVETNLTGVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGVVHAAPYSASKHG
                     VVGFTKALGLELARTGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVP
                     IGRYVQPSEVAEMVAYLIGPGAAAVTAQALNVCGGLGNY"
     misc_feature    complement(34159..34251)
                     /gene_synonym="actIII; SCBAC28G1.12c"
                     /locus_tag="SCO5086"
                     /note="Pfam match to entry PF00678 adh_short_C2, Short
                     chain dehydrogenase/reductase C-terminus, score 25.80,
                     E-value 1.4e-05"
     PFAM_domain     complement(34318..34899)
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00106.28"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5086_0439"
                     /evalue="5.30E-68"
                     /label="SCO5086"
                     /locus_tag="SCO5086"
                     /protein_end="201"
                     /protein_start="7"
                     /score="228.5"
                     /tool="antismash"
                     /translation="VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELRE
                     AGVEADGRTCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVV
                     ETNLTGVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGVVHAAPYSASKHGVVGFTKA
                     LGLELARTGITVNAVCPGFVETPMAASVREH"
     misc_feature    complement(34342..34902)
                     /gene_synonym="actIII; SCBAC28G1.12c"
                     /locus_tag="SCO5086"
                     /note="Pfam match to entry PF00106 adh_short, short chain
                     dehydrogenase, score 302.10, E-value 6.8e-87"
     CDS_motif       complement(34390..34530)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5086_0002"
                     /evalue="5.50E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="SCO5086"
                     /protein_end="177"
                     /protein_start="130"
                     /score="6.2"
                     /tool="antismash"
                     /translation="MLERGTGRIVNIASTGGKQGVVHAAPYSASKHGVVGFTKALGLEL
                     AR"
     misc_feature    complement(34405..34491)
                     /gene_synonym="actIII; SCBAC28G1.12c"
                     /locus_tag="SCO5086"
                     /note="PS00061 Short-chain dehydrogenases/reductases family
                     signature"
     aSDomain        complement(34543..34899)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5086_PKS_KR.1"
                     /evalue="3.50E-12"
                     /label="SCO5086_PKS_KR.1"
                     /locus_tag="SCO5086"
                     /protein_end="126"
                     /protein_start="7"
                     /score="38.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELRE
                     AGVEADGRTCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVV
                     ETNLTGVFRVTKQVL"
     CDS_motif       complement(34825..34893)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5086_0001"
                     /evalue="7.40E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="SCO5086"
                     /protein_end="32"
                     /protein_start="9"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LVTGATSGIGLEIARRLGKEGLR"
     regulatory      34992..34995
                     /regulatory_class="ribosome_binding_site"
     gene            35001..36404
                     /db_xref="GeneID:1100528"
                     /gene_synonym="actIORF1; SCBAC28G1.13"
                     /locus_tag="SCO5087"
     CDS             35001..36404
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (47-437). E-value:
                     6.2e-57. Score: 185.3. Matches aSDomain:
                     nrpspksdomains_SCO5087_PKS_KS.1"
                     /codon_start=1
                     /db_xref="GeneID:1100528"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     768.6; E-value: 3.5e-234)"
                     /gene_kind="biosynthetic"
                     /gene_synonym="actIORF1; SCBAC28G1.13"
                     /locus_tag="SCO5087"
                     /note="SCBAC28G1.13, actIORF1, actinorhodin polyketide
                     beta-ketoacyl synthase alpha subunit, len: 467 aa;
                     identical to C-terminal region of SW:KASA_STRCO
                     (EMBL:X63449) Streptomyces coelicolor actinorhodin
                     polyketide beta-ketoacyl synthase 1 ActI ORF1, 424 aa.
                     Previously sequenced start codon at residue 44 of this
                     sequence. Also similar to TR:CAB45606 (EMBL:AL079356)
                     Streptomyces coelicolor polyketide beta-ketoacyl synthase
                     alpha (WhiE locus) SC6G9.15, 424 aa; fasta scores: opt:
                     1706 Z-score: 1660.2 bits: 316.4 E(): 9.5e-87; 61.871%
                     identity in 417 aa overlap. Contains Pfam matches to
                     entries PF00109 ketoacyl-synt, Beta-ketoacyl synthase,
                     N-terminal domain and PF02801 ketoacyl-synt_C,
                     Beta-ketoacyl synthase, C-terminal domain and match to
                     Prosite entry PS00606 Beta-ketoacyl synthases active site"
                     /product="actinorhodin polyketide beta-ketoacyl synthase
                     subunit alpha"
                     /protein_id="NP_629237.1"
                     /sec_met_domain="t2ks (E-value: 1.9e-236, bitscore: 783.6,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLDAAPVDPASRGPVSAFEPPSSHGADDDDDHRTNASKELFGLK
                     RRVVITGVGVRAPGGNGTRQFWELLTSGRTATRRISFFDPSPYRSQVAAEADFDPVAEG
                     FGPRELDRMDRASQFAVACAREAFAASGLDPDTLDPARVGVSLGSAVAAATSLEREYLL
                     LSDSGRDWEVDAAWLSRHMFDYLVPSVMPAEVAWAVGAEGPVTMVSTGCTSGLDSVGNA
                     VRAIEEGSADVMFAGAADTPITPIVVACFDAIRATTARNDDPEHASRPFDGTRDGFVLA
                     EGAAMFVLEDYDSALARGARIHAEISGYATRCNAYHMTGLKADGREMAETIRVALDESR
                     TDATDIDYINAHGSGTRQNDRHETAAYKRALGEHARRTPVSSIKSMVGHSLGAIGSLEI
                     AACVLALEHGVVPPTANLRTSDPECDLDYVPLEARERKLRSVLTVGSGFGGFQSAMVLR
                     DAETAGAAA"
     misc_feature    35024..40309
                     /note="previously sequenced DNA fragment. EMBL:X63449
                     S.coelicolor genes actIORF1, actIORF2, actIORF3, actVII,
                     actIV and actVB for beta-ketoacyl synthase/acyl
                     transferase, acyl carrier protein, cyclase/dehydrase,
                     dehydrase and dimerase"
     misc_feature    35133..35882
                     /gene_synonym="actIORF1; SCBAC28G1.13"
                     /locus_tag="SCO5087"
                     /note="Pfam match to entry PF00109 ketoacyl-synt,
                     Beta-ketoacyl synthase, N-terminal domain, score 310.40,
                     E-value 2.2e-89"
     PFAM_domain     35136..35882
                     /aSDomain="ketoacyl-synt"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00109.29"
                     /description="Beta-ketoacyl synthase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5087_0440"
                     /evalue="1.40E-58"
                     /label="SCO5087"
                     /locus_tag="SCO5087"
                     /protein_end="294"
                     /protein_start="45"
                     /score="198.6"
                     /tool="antismash"
                     /translation="RRVVITGVGVRAPGGNGTRQFWELLTSGRTATRRISFFDPSPYRS
                     QVAAEADFDPVAEGFGPRELDRMDRASQFAVACAREAFAASGLDPDTLDPARVGVSLGS
                     AVAAATSLEREYLLLSDSGRDWEVDAAWLSRHMFDYLVPSVMPAEVAWAVGAEGPVTMV
                     STGCTSGLDSVGNAVRAIEEGSADVMFAGAADTPITPIVVACFDAIRATTARNDDPEHA
                     SRPFDGTRDGFVLAEGAAMFVLEDYDS"
     aSDomain        35142..36311
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5087_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="6.20E-57"
                     /label="SCO5087_PKS_KS.1"
                     /locus_tag="SCO5087"
                     /protein_end="437"
                     /protein_start="47"
                     /score="185.3"
                     /tool="antismash"
                     /translation="VVITGVGVRAPGGNGTRQFWELLTSGRTATRRISFFDPSPYRSQV
                     AAEADFDPVAEGFGPRELDRMDRASQFAVACAREAFAASGLDPDTLDPARVGVSLGSAV
                     AAATSLEREYLLLSDSGRDWEVDAAWLSRHMFDYLVPSVMPAEVAWAVGAEGPVTMVST
                     GCTSGLDSVGNAVRAIEEGSADVMFAGAADTPITPIVVACFDAIRATTARNDDPEHASR
                     PFDGTRDGFVLAEGAAMFVLEDYDSALARGARIHAEISGYATRCNAYHMTGLKADGREM
                     AETIRVALDESRTDATDIDYINAHGSGTRQNDRHETAAYKRALGEHARRTPVSSIKSMV
                     GHSLGAIGSLEIAACVLALEHGVVPPTANLRTSDPECDLDYVPLEARERK"
     misc_feature    35607..35657
                     /gene_synonym="actIORF1; SCBAC28G1.13"
                     /locus_tag="SCO5087"
                     /note="PS00606 Beta-ketoacyl synthases active site"
     PFAM_domain     35907..36251
                     /aSDomain="Ketoacyl-synt_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02801.25"
                     /description="Beta-ketoacyl synthase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5087_0441"
                     /evalue="1.70E-34"
                     /label="SCO5087"
                     /locus_tag="SCO5087"
                     /protein_end="417"
                     /protein_start="302"
                     /score="118.5"
                     /tool="antismash"
                     /translation="HAEISGYATRCNAYHMTGLKADGREMAETIRVALDESRTDATDID
                     YINAHGSGTRQNDRHETAAYKRALGEHARRTPVSSIKSMVGHSLGAIGSLEIAACVLAL
                     EHGVVPPTANL"
     misc_feature    35907..36383
                     /gene_synonym="actIORF1; SCBAC28G1.13"
                     /locus_tag="SCO5087"
                     /note="Pfam match to entry PF02801 ketoacyl-synt_C,
                     Beta-ketoacyl synthase, C-terminal domain, score 248.10,
                     E-value 1.2e-70"
     misc_feature    36401..37123
                     /gene_synonym="actIORF2; SCBAC28G1.14"
                     /locus_tag="SCO5088"
                     /note="Pfam match to entry PF00109 ketoacyl-synt,
                     Beta-ketoacyl synthase, N-terminal domain, score 279.40,
                     E-value 4.5e-80"
     gene            36401..37624
                     /db_xref="GeneID:1100529"
                     /gene_synonym="actIORF2; SCBAC28G1.14"
                     /locus_tag="SCO5088"
     CDS             36401..37624
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (59-364). E-value:
                     1e-29. Score: 95.6. Matches aSDomain:
                     nrpspksdomains_SCO5088_PKS_KS.1"
                     /codon_start=1
                     /db_xref="GeneID:1100529"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 7
                     (Score: 743.5; E-value: 1.2e-226)"
                     /gene_kind="biosynthetic"
                     /gene_synonym="actIORF2; SCBAC28G1.14"
                     /locus_tag="SCO5088"
                     /note="SCBAC28G1.14, actIORF2, actinorhodin polyketide
                     beta-ketoacyl synthase beta subunit (also known as chain
                     length factor), len: 407 aa; identical to previously
                     sequenced SW:KASB_STRCO (EMBL:X63449) Streptomyces
                     coelicolor actinorhodin polyketide beta-ketoacyl synthase 2
                     ActI ORF2, 407 aa. Contains Pfam matches to entries PF00109
                     ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain
                     and PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase,
                     C-terminal domain"
                     /product="actinorhodin polyketide beta-ketoacyl synthase
                     subunit beta"
                     /protein_id="NP_629238.1"
                     /sec_met_domain="t2clf (E-value: 4.9e-206, bitscore: 682.9,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVLITGVGVVAPNGLGLAPYWSAVLDGRHGLGPVTRFDVSRYPA
                     TLAGQIDDFHAPDHIPGRLLPQTDPSTRLALTAADWALQDAKADPESLTDYDMGVVTAN
                     ACGGFDFTHREFRKLWSEGPKSVSVYESFAWFYAVNTGQISIRHGMRGPSSALVAEQAG
                     GLDALGHARRTIRRGTPLVVSGGVDSALDPWGWVSQIASGRISTATDPDRAYLPFDERA
                     AGYVPGEGGAILVLEDSAAAEARGRHDAYGELAGCASTFDPAPGSGRPAGLERAIRLAL
                     NDAGTGPEDVDVVFADGAGVPELDAAEARAIGRVFGREGVPVTVPKTTTGRLYSGGGPL
                     DVVTALMSLREGVIAPTAGVTSVPREYGIDLVLGEPRSTAPRTALVLARGRWGFNSAAV
                     LRRFAPTP"
     PFAM_domain     36407..37117
                     /aSDomain="ketoacyl-synt"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00109.29"
                     /description="Beta-ketoacyl synthase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5088_0442"
                     /evalue="9.30E-41"
                     /label="SCO5088"
                     /locus_tag="SCO5088"
                     /protein_end="239"
                     /protein_start="2"
                     /score="140.2"
                     /tool="antismash"
                     /translation="VLITGVGVVAPNGLGLAPYWSAVLDGRHGLGPVTRFDVSRYPATL
                     AGQIDDFHAPDHIPGRLLPQTDPSTRLALTAADWALQDAKADPESLTDYDMGVVTANAC
                     GGFDFTHREFRKLWSEGPKSVSVYESFAWFYAVNTGQISIRHGMRGPSSALVAEQAGGL
                     DALGHARRTIRRGTPLVVSGGVDSALDPWGWVSQIASGRISTATDPDRAYLPFDERAAG
                     YVPGEGGAILVLEDS"
     aSDomain        36578..37492
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5088_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.00E-29"
                     /label="SCO5088_PKS_KS.1"
                     /locus_tag="SCO5088"
                     /protein_end="364"
                     /protein_start="59"
                     /score="95.6"
                     /tool="antismash"
                     /translation="IPGRLLPQTDPSTRLALTAADWALQDAKADPESLTDYDMGVVTAN
                     ACGGFDFTHREFRKLWSEGPKSVSVYESFAWFYAVNTGQISIRHGMRGPSSALVAEQAG
                     GLDALGHARRTIRRGTPLVVSGGVDSALDPWGWVSQIASGRISTATDPDRAYLPFDERA
                     AGYVPGEGGAILVLEDSAAAEARGRHDAYGELAGCASTFDPAPGSGRPAGLERAIRLAL
                     NDAGTGPEDVDVVFADGAGVPELDAAEARAIGRVFGREGVPVTVPKTTTGRLYSGGGPL
                     DVVTALMSLREGVIAPTAGVTSVP"
     CDS_motif       37052..37090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5088_0001"
                     /evalue="5.10E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="SCO5088"
                     /protein_end="230"
                     /protein_start="217"
                     /score="13.2"
                     /tool="antismash"
                     /translation="FDERAAGYVPGEG"
     PFAM_domain     37151..37480
                     /aSDomain="Ketoacyl-synt_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02801.25"
                     /description="Beta-ketoacyl synthase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5088_0443"
                     /evalue="5.20E-21"
                     /label="SCO5088"
                     /locus_tag="SCO5088"
                     /protein_end="360"
                     /protein_start="250"
                     /score="75.0"
                     /tool="antismash"
                     /translation="YGELAGCASTFDPAPGSGRPAGLERAIRLALNDAGTGPEDVDVVF
                     ADGAGVPELDAAEARAIGRVFGREGVPVTVPKTTTGRLYSGGGPLDVVTALMSLREGVI
                     APTAGV"
     misc_feature    37151..37612
                     /gene_synonym="actIORF2; SCBAC28G1.14"
                     /locus_tag="SCO5088"
                     /note="Pfam match to entry PF02801 ketoacyl-synt_C,
                     Beta-ketoacyl synthase, C-terminal domain, score 188.60,
                     E-value 1e-52"
     regulatory      37639..37642
                     /regulatory_class="ribosome_binding_site"
     gene            37649..37909
                     /db_xref="GeneID:1100530"
                     /gene_synonym="actIORF3; SCBAC28G1.15"
                     /locus_tag="SCO5089"
     CDS             37649..37909
                     /NRPS_PKS="Domain: ACP (13-81). E-value: 9.7e-14. Score:
                     43.4. Matches aSDomain: nrpspksdomains_SCO5089_ACP.1"
                     /codon_start=1
                     /db_xref="GeneID:1100530"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129: acyl carrier protein"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 114.2; E-value: 5e-36)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="actIORF3; SCBAC28G1.15"
                     /locus_tag="SCO5089"
                     /note="SCBAC28G1.15, actIORF3, actinorhodin polyketide
                     synthase acyl carrier protein, len: 86 aa; identical to
                     previously sequenced SW:ACPA_STRCO (EMBL:X63449)
                     Streptomyces coelicolor actinorhodin polyketide synthase
                     acyl carrier protein ActI ORF3, 86 aa. Contains Pfam match
                     to entry PF00550 pp-binding, Phosphopantetheine attachment
                     site and match to Prosite entry PS00012 Phosphopantetheine
                     attachment site"
                     /product="actinorhodin polyketide synthase"
                     /protein_id="NP_629239.1"
                     /sec_met_domain="PP-binding (E-value: 1.3e-08, bitscore:
                     34.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATLLTTDDLRRALVECAGETDGTDLSGDFLDLRFEDIGYDSLAL
                     METAARLESRYGVSIPDDVAGRVDTPRELLDLINGALAEAA"
     misc_feature    37682..37882
                     /gene_synonym="actIORF3; SCBAC28G1.15"
                     /locus_tag="SCO5089"
                     /note="Pfam match to entry PF00550 pp-binding,
                     Phosphopantetheine attachment site, score 68.00, E-value
                     3.4e-17"
     PFAM_domain     37685..37882
                     /aSDomain="PP-binding"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00550.28"
                     /description="Phosphopantetheine attachment site"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5089_0444"
                     /evalue="4.40E-10"
                     /label="SCO5089"
                     /locus_tag="SCO5089"
                     /protein_end="78"
                     /protein_start="12"
                     /score="39.9"
                     /tool="antismash"
                     /translation="ALVECAGETDGTDLSGDFLDLRFEDIGYDSLALMETAARLESRYG
                     VSIPDDVAGRVDTPRELLDLI"
     aSDomain        37688..37891
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5089_ACP.1"
                     /evalue="9.70E-14"
                     /label="SCO5089_ACP.1"
                     /locus_tag="SCO5089"
                     /protein_end="81"
                     /protein_start="13"
                     /score="43.4"
                     /tool="antismash"
                     /translation="LVECAGETDGTDLSGDFLDLRFEDIGYDSLALMETAARLESRYGV
                     SIPDDVAGRVDTPRELLDLINGA"
     misc_feature    37757..37804
                     /gene_synonym="actIORF3; SCBAC28G1.15"
                     /locus_tag="SCO5089"
                     /note="PS00012 Phosphopantetheine attachment site"
     regulatory      37898..37901
                     /gene_synonym="actIORF3; SCBAC28G1.15"
                     /locus_tag="SCO5089"
                     /regulatory_class="ribosome_binding_site"
     gene            37906..38856
                     /db_xref="GeneID:1100531"
                     /gene_synonym="actVII; SCBAC28G1.16"
                     /locus_tag="SCO5090"
     CDS             37906..38856
                     /NRPS_PKS="Domain: Polyketide_cyc (15-125). E-value: 2e-13.
                     Score: 42.6. Matches aSDomain:
                     nrpspksdomains_SCO5090_Polyketide_cyc.1"
                     /codon_start=1
                     /db_xref="GeneID:1100531"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128: cyclase/dehydrase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 404.0; E-value: 7.8e-124)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="actVII; SCBAC28G1.16"
                     /locus_tag="SCO5090"
                     /note="SCBAC28G1.16, actVII, actinorhodin polyketide
                     synthase bifunctional cyclase/dehydratase, len: 316 aa;
                     identical to previously sequenced SW:CYPK_STRCO
                     (EMBL:X63449) Streptomyces coelicolor actinorhodin
                     polyketide synthase bifunctional cyclase/dehydratase ActI
                     ORF4, 316 aa"
                     /product="actinorhodin polyketide synthase bifunctional
                     cyclase/dehydratase"
                     /protein_id="NP_629240.1"
                     /transl_table=11
                     /translation="MSRPGEHRVVHTLRTQAPARRLYELVARVEDWPAVFEPTVHVQVL
                     ERGPGTERFRIWARVGGRVKTWTSRRTLDPDTLRVTFRQELTQPPIASMGGSWEFRGDG
                     DGTEVVLTHDFAAVDEAALPGLREALDANSGKELAALVALAERRQPPEELVFTFEDTLR
                     VPSGDDAYAFIERSDLWQERLPHVRKVTLTEEAAGTGPAETRDMTVQDMTMETVTTDGG
                     THTTRSIRLCVPARSIVYKQLVPPALLSGHCGAWTFGEDTVTARHTVAIDPARVEEVLG
                     KGATVADARTHLREVLGANSRATLRHAAAAAGPAS"
     aSDomain        37951..38280
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5090_Polyketide_cyc.1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="2.00E-13"
                     /label="SCO5090_Polyketide_cyc.1"
                     /locus_tag="SCO5090"
                     /protein_end="125"
                     /protein_start="15"
                     /score="42.6"
                     /tool="antismash"
                     /translation="QAPARRLYELVARVEDWPAVFEPTVHVQVLERGPGTERFRIWARV
                     GGRVKTWTSRRTLDPDTLRVTFRQELTQPPIASMGGSWEFRGDGDGTEVVLTHDFAAVD
                     EAALPG"
     PFAM_domain     37951..38280
                     /aSDomain="Polyketide_cyc"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03364.23"
                     /description="Polyketide cyclase / dehydrase and lipid
                     transport"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5090_0445"
                     /evalue="6.60E-11"
                     /label="SCO5090"
                     /locus_tag="SCO5090"
                     /protein_end="125"
                     /protein_start="15"
                     /score="42.6"
                     /tool="antismash"
                     /translation="QAPARRLYELVARVEDWPAVFEPTVHVQVLERGPGTERFRIWARV
                     GGRVKTWTSRRTLDPDTLRVTFRQELTQPPIASMGGSWEFRGDGDGTEVVLTHDFAAVD
                     EAALPG"
     gene            38853..39746
                     /db_xref="GeneID:1100532"
                     /gene_synonym="actIV; SCBAC28G1.17"
                     /locus_tag="SCO5091"
     CDS             38853..39746
                     /codon_start=1
                     /db_xref="GeneID:1100532"
                     /gene_functions="resistance (resist) ClassB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C5-C14
                     (Score: 467.3; E-value: 4.4e-143)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="actIV; SCBAC28G1.17"
                     /locus_tag="SCO5091"
                     /note="SCBAC28G1.17, actIV, cyclase, len: 297 aa; identical
                     to previously sequenced TR:Q02057 (EMBL:X63449)
                     Streptomyces coelicolor dehydrogenase ActI ORF5, 297 aa.
                     Contains Pfam match to entry PF00753 lactamase_B,
                     Metallo-beta-lactamase superfamily"
                     /product="cyclase"
                     /protein_id="NP_629241.1"
                     /transl_table=11
                     /translation="MTVEVREVAEGVYAYEQAPGGWCVSNAGIVVGGDGALVVDTLSTI
                     PRARRLAEWVDKLAAGPGRTVVNTHFHGDHAFGNQVFAPGTRIIAHEDMRSAMVTTGLA
                     LTGLWPRVDWGEIELRPPNVTFRDRLTLHVGERQVELICVGPAHTDHDVVVWLPEERVL
                     FAGDVVMSGVTPFALFGSVAGTLAALDRLAELEPEVVVGGHGPVAGPEVIDANRDYLRW
                     VQRLAADAVDRRLTPLQAARRADLGAFAGLLDAERLVANLHRAHEELLGGHVRDAMAIF
                     AELVAYNGGQLPTCLA"
     misc_feature    38910..39464
                     /gene_synonym="actIV; SCBAC28G1.17"
                     /locus_tag="SCO5091"
                     /note="Pfam match to entry PF00753 lactamase_B,
                     Metallo-beta-lactamase superfamily, score 124.60, E-value
                     1.9e-33"
     PFAM_domain     38913..39464
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00753.30"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5091_0446"
                     /evalue="6.20E-28"
                     /label="SCO5091"
                     /locus_tag="SCO5091"
                     /protein_end="204"
                     /protein_start="20"
                     /score="98.3"
                     /tool="antismash"
                     /translation="GWCVSNAGIVVGGDGALVVDTLSTIPRARRLAEWVDKLAAGPGRT
                     VVNTHFHGDHAFGNQVFAPGTRIIAHEDMRSAMVTTGLALTGLWPRVDWGEIELRPPNV
                     TFRDRLTLHVGERQVELICVGPAHTDHDVVVWLPEERVLFAGDVVMSGVTPFALFGSVA
                     GTLAALDRLAELEPEVVVGGH"
     regulatory      39747..39750
                     /regulatory_class="ribosome_binding_site"
     gene            39758..40291
                     /db_xref="GeneID:1100533"
                     /gene_synonym="actVB; SCBAC28G1.18"
                     /locus_tag="SCO5092"
     CDS             39758..40291
                     /codon_start=1
                     /db_xref="GeneID:1100533"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="actVB; SCBAC28G1.18"
                     /locus_tag="SCO5092"
                     /note="SCBAC28G1.18, actVB, actinorhodin polyketide
                     possible dimerase, len: 177 aa; identical to previously
                     sequenced SW:DIM6_STRCO (EMBL:X63449) Streptomyces
                     coelicolor actinorhodin polyketide dimerase ActI ORF6,
                     ActVB, 177 aa Contains Pfam match to entry PF01613
                     Flavin_Reduct, Flavin reductase like domain"
                     /product="actinorhodin polyketide dimerase"
                     /protein_id="NP_629242.1"
                     /transl_table=11
                     /translation="MAADQGMLRDAMARVPAGVALVTAHDRGGVPHGFTASSFVSVSME
                     PPLALVCLARTANSFPVFDSCGEFAVSVLREDHTDLAMRFARKSADKFAGGEFVRTARG
                     ATVLDGAVAVVECTVHERYPAGDHIILLGEVQSVHVEEKGVPAVYVDRRFAALCSAAGA
                     CPSATGRGVPAHAG"
     PFAM_domain     39791..40225
                     /aSDomain="Flavin_Reduct"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01613.21"
                     /db_xref="GO:0010181"
                     /description="Flavin reductase like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5092_0447"
                     /evalue="1.60E-36"
                     /gene_ontologies="GO:0010181: FMN binding"
                     /label="SCO5092"
                     /locus_tag="SCO5092"
                     /protein_end="156"
                     /protein_start="11"
                     /score="125.9"
                     /tool="antismash"
                     /translation="MARVPAGVALVTAHDRGGVPHGFTASSFVSVSMEPPLALVCLART
                     ANSFPVFDSCGEFAVSVLREDHTDLAMRFARKSADKFAGGEFVRTARGATVLDGAVAVV
                     ECTVHERYPAGDHIILLGEVQSVHVEEKGVPAVYVDRRFAA"
     misc_feature    39791..40231
                     /gene_synonym="actVB; SCBAC28G1.18"
                     /locus_tag="SCO5092"
                     /note="Pfam match to entry PF01613 Flavin_Reduct, Flavin
                     reductase like domain, score 254.60, E-value 1.3e-72"
     misc_feature    40279..45130
                     /note="previously sequenced DNA fragment. EMBL:Y18817
                     Streptomyces coelicolor A3(2) transcriptional regulator and
                     actinorhodin biosynthetic genes, strain J1501"
     gene            complement(40310..40807)
                     /db_xref="GeneID:1100534"
                     /gene_synonym="ORF7; SCBAC28G1.19c"
                     /locus_tag="SCO5093"
     CDS             complement(40310..40807)
                     /codon_start=1
                     /db_xref="GeneID:1100534"
                     /gene_synonym="ORF7; SCBAC28G1.19c"
                     /locus_tag="SCO5093"
                     /note="SCBAC28G1.19c, ORF7, mini-circle protein, len: 165
                     aa; identical to previously sequenced TR:Q9X9V2
                     (EMBL:Y18817) Streptomyces coelicolor A3(2) mini-circle
                     protein ORF7, 165 aa"
                     /product="mini-circle protein"
                     /protein_id="NP_629243.1"
                     /transl_table=11
                     /translation="MPTTPRTHRRDTPPPRTGGGEAETLRGFLDYLRTSIAGKVEDAPE
                     PQVRTAAVASGTNLLGLLNHLTHVERAVFLGEEVRSWPATFRAASQDGVADVVARYREA
                     VERANRVLDACTDLGAPLPRPRPGRPAPSVRWALTHMVEETGRHAGHADILRELIDGAT
                     GR"
     PFAM_domain     complement(40325..40738)
                     /aSDomain="DUF664"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04978.15"
                     /description="Protein of unknown function (DUF664)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5093_0448"
                     /evalue="1.90E-38"
                     /label="SCO5093"
                     /locus_tag="SCO5093"
                     /protein_end="161"
                     /protein_start="23"
                     /score="132.4"
                     /tool="antismash"
                     /translation="TLRGFLDYLRTSIAGKVEDAPEPQVRTAAVASGTNLLGLLNHLTH
                     VERAVFLGEEVRSWPATFRAASQDGVADVVARYREAVERANRVLDACTDLGAPLPRPRP
                     GRPAPSVRWALTHMVEETGRHAGHADILRELIDG"
     regulatory      complement(40817..40821)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(40861..41487)
                     /db_xref="GeneID:1100535"
                     /gene_synonym="ORF8; SCBAC28G1.20c"
                     /locus_tag="SCO5094"
     CDS             complement(40861..41487)
                     /NRPS_PKS="Domain: oMT (41-138). E-value: 1.3e-11. Score:
                     35.1. Matches aSDomain: nrpspksdomains_SCO5094_oMT.1"
                     /codon_start=1
                     /db_xref="GeneID:1100535"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     (Score: 32.7; E-value: 9.8e-11)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="ORF8; SCBAC28G1.20c"
                     /locus_tag="SCO5094"
                     /note="SCBAC28G1.20c, ORF8, methyltransferase, len: 208 aa;
                     identical to previously sequenced TR:Q9X9V1 (EMBL:Y18817)
                     Streptomyces coelicolor A3(2) methyltransferase ORF8, 208
                     aa"
                     /product="methyltransferase"
                     /protein_id="NP_629244.1"
                     /transl_table=11
                     /translation="MSTTDAVTFWDGVYAARPAPDAPRPNVRLVETVTGLPPGDALDLG
                     CGSGGDALWLARRGWRVTAVDISGVAAERLAGHARTHGLGDLVDAVRHDLRDSFPEGRF
                     DLVSAHYLHTPFDLDRASVLRGAAHALRPGGRLLVVDHGSTAPWSWDQDPDARHPAPQE
                     VAADLALDPATWRVERAEAPRRTATGPGGRTAEVVDHVLLVRRAD"
     PFAM_domain     complement(41071..41364)
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08241.15"
                     /db_xref="GO:0008757"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5094_0449"
                     /evalue="1.00E-14"
                     /gene_ontologies="GO:0008757:
                     S-adenosylmethionine-dependent methyltransferase activity"
                     /label="SCO5094"
                     /locus_tag="SCO5094"
                     /protein_end="139"
                     /protein_start="41"
                     /score="55.1"
                     /tool="antismash"
                     /translation="LDLGCGSGGDALWLARRGWRVTAVDISGVAAERLAGHARTHGLGD
                     LVDAVRHDLRDSFPEGRFDLVSAHYLHTPFDLDRASVLRGAAHALRPGGRLLV"
     aSDomain        complement(41074..41364)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5094_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.30E-11"
                     /label="SCO5094_oMT.1"
                     /locus_tag="SCO5094"
                     /protein_end="138"
                     /protein_start="41"
                     /score="35.1"
                     /tool="antismash"
                     /translation="LDLGCGSGGDALWLARRGWRVTAVDISGVAAERLAGHARTHGLGD
                     LVDAVRHDLRDSFPEGRFDLVSAHYLHTPFDLDRASVLRGAAHALRPGGRLL"
     regulatory      complement(41493..41498)
                     /regulatory_class="ribosome_binding_site"
     gene            41622..42194
                     /db_xref="GeneID:1100536"
                     /gene_synonym="ORF9; SCBAC28G1.21"
                     /locus_tag="SCO5095"
     CDS             41622..42194
                     /codon_start=1
                     /db_xref="GeneID:1100536"
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /gene_synonym="ORF9; SCBAC28G1.21"
                     /locus_tag="SCO5095"
                     /note="SCBAC28G1.21, ORF9, probable DNA-binding protein,
                     len: 190 aa; identical to previously sequenced as TR:Q9X9V0
                     (EMBL:Y18817) Streptomyces coelicolor A3(2) hypothetical
                     20.6 kDa protein ORF9, 190 aa and similar to TR:O86784
                     (EMBL:AL031317) Streptomyces coelicolor SC6G4.21, 202 aa;
                     fasta scores: opt: 642 Z-score: 656.2 bits: 128.2 E():
                     7.9e-31; 53.968% identity in 189 aa overlap. Contains Pfam
                     match to entry PF01381 HTH_3, Helix-turn-helix and possible
                     helix-turn-helix motif at residues 25..46 (+6.01 SD)"
                     /product="DNA-binding protein"
                     /protein_id="NP_629245.1"
                     /transl_table=11
                     /translation="MDAATDDVLDAVGPRLRTLRRERGITLAHLSAATGVSESTLSRLE
                     SGQRRATLELLLPLARIYDVPLDDLVGAPRTGDPRIHLKPVRRFGMVFVPLSRRPGGTQ
                     AFKMIIPSRPAPLEPTPQTHEGSEWLYVLSGRLRLLVGERDLTLSPGEAAEFDTSLPHW
                     LGSADGGAVELLVLFGLQGVRAHVHSG"
     misc_feature    41667..41831
                     /gene_synonym="ORF9; SCBAC28G1.21"
                     /locus_tag="SCO5095"
                     /note="Pfam match to entry PF01381 HTH_3, Helix-turn-helix,
                     score 59.50, E-value 7.3e-14"
     PFAM_domain     41667..41831
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01381.25"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5095_0450"
                     /evalue="3.20E-13"
                     /label="SCO5095"
                     /locus_tag="SCO5095"
                     /protein_end="70"
                     /protein_start="15"
                     /score="49.6"
                     /tool="antismash"
                     /translation="LRTLRRERGITLAHLSAATGVSESTLSRLESGQRRATLELLLPLA
                     RIYDVPLDDL"
     PFAM_domain     41976..42152
                     /aSDomain="Cupin_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07883.14"
                     /description="Cupin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5095_0451"
                     /evalue="5.20E-13"
                     /label="SCO5095"
                     /locus_tag="SCO5095"
                     /protein_end="177"
                     /protein_start="118"
                     /score="48.6"
                     /tool="antismash"
                     /translation="PTPQTHEGSEWLYVLSGRLRLLVGERDLTLSPGEAAEFDTSLPHW
                     LGSADGGAVELLVL"
     gene            complement(42446..43375)
                     /db_xref="GeneID:1100537"
                     /gene_synonym="SCBAC28G1.22c"
                     /locus_tag="SCO5096"
     CDS             complement(42446..43375)
                     /codon_start=1
                     /db_xref="GeneID:1100537"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="SCBAC28G1.22c"
                     /locus_tag="SCO5096"
                     /note="SCBAC28G1.22c, LysR-family transcriptional
                     regulatory protein, len: 309 aa; identical to previously
                     sequenced TR:Q9X9U9 (EMBL:Y18817) Streptomyces coelicolor
                     A3(2) transcriptional regulator of LysR family, 307 aa.
                     Contains Pfam match to entry PF00126 HTH_1, Bacterial
                     regulatory helix-turn-helix protein, lysR family and match
                     to Prosite entry PS00044 Bacterial regulatory proteins,
                     lysR family signature. Also contains a possible
                     helix-turn-helix motif at residues 22..43 (+5.22 SD)"
                     /product="LysR family transcriptional regulator"
                     /protein_id="NP_629246.1"
                     /transl_table=11
                     /translation="MGMTTDVHVRELRYFATVAEELHFTRAAELLYVSQPALSKQIRAL
                     ERQLGAELFHRGPRGVTLTEAGTALLPHARRMLADWTEGAAAVEAARAARRDTLVVGMS
                     TSPGRGGLLPAIRSRFTAAHPEAVLQLRQMSWEDPTAGLADGTADVAYVWLPLPDADRY
                     AWTVVAEEPRLVALPDSHPLAAREEIDFADLAGEPFLALPPEAGVLRDFWLALDERRAL
                     DGPAARPPRVGAEISGTEETYEALVAGLGICLVATGNAPLITLGGVVTRPVRGLSPSRY
                     ALARRREDEGRALVRGYVEACRRVTDRA"
     PFAM_domain     complement(42461..43093)
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03466.23"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5096_0453"
                     /evalue="2.10E-39"
                     /label="SCO5096"
                     /locus_tag="SCO5096"
                     /protein_end="305"
                     /protein_start="94"
                     /score="135.2"
                     /tool="antismash"
                     /translation="RRDTLVVGMSTSPGRGGLLPAIRSRFTAAHPEAVLQLRQMSWEDP
                     TAGLADGTADVAYVWLPLPDADRYAWTVVAEEPRLVALPDSHPLAAREEIDFADLAGEP
                     FLALPPEAGVLRDFWLALDERRALDGPAARPPRVGAEISGTEETYEALVAGLGICLVAT
                     GNAPLITLGGVVTRPVRGLSPSRYALARRREDEGRALVRGYVEACRRV"
     misc_feature    complement(42920..43351)
                     /gene_synonym="SCBAC28G1.22c"
                     /locus_tag="SCO5096"
                     /note="Pfam match to entry PF00126 HTH_1, Bacterial
                     regulatory helix-turn-helix protein, lysR family, score
                     160.50, E-value 2.8e-44"
     PFAM_domain     complement(43175..43348)
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00126.30"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5096_0452"
                     /evalue="1.60E-23"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO5096"
                     /locus_tag="SCO5096"
                     /protein_end="67"
                     /protein_start="9"
                     /score="82.5"
                     /tool="antismash"
                     /translation="RELRYFATVAEELHFTRAAELLYVSQPALSKQIRALERQLGAELF
                     HRGPRGVTLTEAG"
     misc_feature    complement(43217..43309)
                     /gene_synonym="SCBAC28G1.22c"
                     /locus_tag="SCO5096"
                     /note="PS00044 Bacterial regulatory proteins, lysR family
                     signature"
     regulatory      43461..43464
                     /regulatory_class="ribosome_binding_site"
     gene            43470..44300
                     /db_xref="GeneID:1100538"
                     /gene_synonym="SCBAC28G1.23"
                     /locus_tag="SCO5097"
     CDS             43470..44300
                     /NRPS_PKS="Domain: PKS_KR (3-155). E-value: 2.9e-10. Score:
                     32.3. Matches aSDomain: nrpspksdomains_SCO5097_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:1100538"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     129.8; E-value: 3.3e-40)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCBAC28G1.23"
                     /locus_tag="SCO5097"
                     /note="SCBAC28G1.23, short-chain oxidoreductase, len: 276
                     aa; identical to previously sequenced TR:Q9X9U8
                     (EMBL:Y18817) Streptomyces coelicolor A3(2) oxidoreductase
                     of short-chain, 276 aa. Contains Pfam match to entry
                     PF00106 adh_short, short chain dehydrogenase and match to
                     Prosite entry PS00061 Short-chain dehydrogenases/reductases
                     family signature"
                     /product="short-chain oxidoreductase"
                     /protein_id="NP_629247.1"
                     /sec_met_domain="adh_short (E-value: 4.8e-31, bitscore:
                     106.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKVWLITGASSGFGRAIAEAALADGDVVVGAARRPEALDDLVAA
                     HPDQMEALRLDVADTAAAGDAVRDVVARHGRVDVLVNNAGRTHVGALEETGEDELRALF
                     DVHVFGPAALTRAVLPSMRERRSGAIVQMSSMGGQMSFAGFSAYSGTKFALEGMSEGLA
                     DEVRDFGIKVLIVEPGSFRTGLFEAGNAGISADSGVYAKVGETRGMIAAGDGSQPGDPA
                     RAAAVIRAALAAEHTPLRLPLGDDGVTAVLGHLDRVREEVETWEKQTRATAFDD"
     misc_feature    43476..44021
                     /gene_synonym="SCBAC28G1.23"
                     /locus_tag="SCO5097"
                     /note="Pfam match to entry PF00106 adh_short, short chain
                     dehydrogenase, score 211.20, E-value 1.6e-59"
     PFAM_domain     43476..44033
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00106.28"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5097_0454"
                     /evalue="5.90E-49"
                     /label="SCO5097"
                     /locus_tag="SCO5097"
                     /protein_end="188"
                     /protein_start="2"
                     /score="166.3"
                     /tool="antismash"
                     /translation="KVWLITGASSGFGRAIAEAALADGDVVVGAARRPEALDDLVAAHP
                     DQMEALRLDVADTAAAGDAVRDVVARHGRVDVLVNNAGRTHVGALEETGEDELRALFDV
                     HVFGPAALTRAVLPSMRERRSGAIVQMSSMGGQMSFAGFSAYSGTKFALEGMSEGLADE
                     VRDFGIKVLIVEPGSFRTGLFEA"
     CDS_motif       43479..43529
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO5097_0001"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="SCO5097"
                     /protein_end="20"
                     /protein_start="3"
                     /score="11.6"
                     /tool="antismash"
                     /translation="VWLITGASSGFGRAIAE"
     aSDomain        43479..43934
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO5097_PKS_KR.1"
                     /evalue="2.90E-10"
                     /label="SCO5097_PKS_KR.1"
                     /locus_tag="SCO5097"
                     /protein_end="155"
                     /protein_start="3"
                     /score="32.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VWLITGASSGFGRAIAEAALADGDVVVGAARRPEALDDLVAAHPD
                     QMEALRLDVADTAAAGDAVRDVVARHGRVDVLVNNAGRTHVGALEETGEDELRALFDVH
                     VFGPAALTRAVLPSMRERRSGAIVQMSSMGGQMSFAGFSAYSGTKFAL"
     misc_feature    43872..43958
                     /gene_synonym="SCBAC28G1.23"
                     /locus_tag="SCO5097"
                     /note="PS00061 Short-chain dehydrogenases/reductases family
                     signature"
     gene            44358..44822
                     /db_xref="GeneID:1100539"
                     /gene_synonym="ORF12; SCBAC28G1.24"
                     /locus_tag="SCO5098"
     CDS             44358..44822
                     /codon_start=1
                     /db_xref="GeneID:1100539"
                     /gene_synonym="ORF12; SCBAC28G1.24"
                     /locus_tag="SCO5098"
                     /note="SCBAC28G1.24, possible integral membrane protein,
                     len: 154 aa; identical in its C-terminal domain to
                     TR:Q9X9U7 (EMBL:Y18817) Streptomyces coelicolor A3(2)
                     hypothetical 11.9 kDa protein ORF11, 113 aa. Contains
                     possible hydrophobic membrane spanning regions and 10x
                     degenerate repeat at N-terminal region: M(P/V). Alternative
                     start codon in previously sequence EMBL entrance after the
                     repeat region at residue 42"
                     /product="hypothetical protein"
                     /protein_id="NP_629248.1"
                     /transl_table=11
                     /translation="MPDCTRPCPIVPVPMPMPMPMPMPMPMPVPVPASVPNQESAVLSS
                     LKAVNLLVMFLLELAVYTAVVLWGVAVGGTWPVEVALGVGAPVVMMAAWALFGSPRARR
                     PARGAGRFVLEVLWFGAGAAALAASGRPWWAAALAGVCLVNAVLRRLWKQ"
     repeat_region   44391..44450
                     /gene_synonym="ORF12; SCBAC28G1.24"
                     /locus_tag="SCO5098"
                     /note="10x degenerate repeat translated in SCBAC28G1.24"
     PFAM_domain     44511..44783
                     /aSDomain="DUF2568"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF10823.11"
                     /description="Protein of unknown function (DUF2568)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5098_0455"
                     /evalue="1.90E-24"
                     /label="SCO5098"
                     /locus_tag="SCO5098"
                     /protein_end="142"
                     /protein_start="51"
                     /score="85.9"
                     /tool="antismash"
                     /translation="LVMFLLELAVYTAVVLWGVAVGGTWPVEVALGVGAPVVMMAAWAL
                     FGSPRARRPARGAGRFVLEVLWFGAGAAALAASGRPWWAAALAGVC"
     gene            44932..46062
                     /db_xref="GeneID:1100540"
                     /gene_synonym="SCBAC28G1.25"
                     /locus_tag="SCO5099"
     CDS             44932..46062
                     /codon_start=1
                     /db_xref="GeneID:1100540"
                     /gene_synonym="SCBAC28G1.25"
                     /locus_tag="SCO5099"
                     /note="SCBAC28G1.25, possible membrane protein, len: 376
                     aa. Contains possible hydrophobic membrane spanning
                     regions"
                     /product="hypothetical protein"
                     /protein_id="NP_629249.1"
                     /transl_table=11
                     /translation="MSIPPPPGPQGQYPQGPYAPQWGHPLAPYPRPAPVSGLAVAAFVL
                     GVLCFLPAVGLVLGLVALARIRRRGERGKGFAVAGCVLSSVGLALWTLTLSTGAAGDFW
                     DGFRDAARGGGTAYSLEKGQCFTTPSGSLQGVTYDVDEVPCAREHDGEVFASFDLPDGS
                     YPGDGEITRAADDRCYALQDAYAMDRWALPTDVDVYYLTPTAASWRTGDREITCLFGNT
                     DERGTLTGSLRNDGARFDADQHTYLLAEGYLNRAMDEVPAAEAVEDDLAGYRTWAGQVS
                     EALRGEVAMLDGHEWPAGAERPVAALTDDLRSAQEEWGLAAKAADLDAYYEHYGKGYDL
                     VVADSTVTARKALGLATTPPDYEGGEGGGDDPGVEV"
     PFAM_domain     45043..45210
                     /aSDomain="DUF4190"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13828.9"
                     /description="Domain of unknown function (DUF4190)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5099_0456"
                     /evalue="2.70E-16"
                     /label="SCO5099"
                     /locus_tag="SCO5099"
                     /protein_end="93"
                     /protein_start="37"
                     /score="59.2"
                     /tool="antismash"
                     /translation="LAVAAFVLGVLCFLPAVGLVLGLVALARIRRRGERGKGFAVAGCV
                     LSSVGLALWTL"
     PFAM_domain     45298..45621
                     /aSDomain="Septum_form"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13845.9"
                     /description="Septum formation"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5099_0457"
                     /evalue="8.10E-11"
                     /label="SCO5099"
                     /locus_tag="SCO5099"
                     /protein_end="230"
                     /protein_start="122"
                     /score="42.0"
                     /tool="antismash"
                     /translation="GQCFTTPSGSLQGVTYDVDEVPCAREHDGEVFASFDLPDGSYPGD
                     GEITRAADDRCYALQDAYAMDRWALPTDVDVYYLTPTAASWRTGDREITCLFGNTDERG
                     TLTG"
     misc_feature    46179..46197
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.0"
                     /tool="antismash"
     regulatory      46200..46203
                     /regulatory_class="ribosome_binding_site"
     gene            46210..46962
                     /db_xref="GeneID:1100541"
                     /gene_synonym="SCBAC28G1.26"
                     /locus_tag="SCO5100"
     CDS             46210..46962
                     /codon_start=1
                     /db_xref="GeneID:1100541"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="SCBAC28G1.26"
                     /locus_tag="SCO5100"
                     /note="SCBAC28G1.26, possible gntR-family regulatory
                     protein, len: 250 aa; low similarity to SW:FARR_ECOLI
                     (EMBL:X15790) Escherichia coli fatty acid responsive
                     regulator (P30 protein) FarR, 240 aa; fasta scores: opt:
                     206 Z-score: 237.6 bits: 51.4 E(): 1.3e-05; 25.926%
                     identity in 243 aa overlap. Contains Pfam match to entry
                     PF00392 gntR, Bacterial regulatory proteins, gntR family"
                     /product="GntR family transcriptional regulator"
                     /protein_id="NP_629250.1"
                     /transl_table=11
                     /translation="MTFGEQPAYLRVAGDLRKKIADGLLPPHTRLPSQARIREEYGVSD
                     TVALEARKVLMAEGLVEGRSGSGTYVRERPVPRRVARSGYRPAGGATPFRQEQADGDAR
                     GTWESRSEQAEASGAVAERLGIKPGDRVMCTRYVFREAGEAVMLSTSWEPLDLTGRTPV
                     MLPEEGPLGGMGVVERMAAIDVVVDNVTEEVGARPGLAEELLALGGVPGHVVLVVQRTF
                     YASGRAVETADVVVPADRYRVAYHLPVR"
     PFAM_domain     46234..46422
                     /aSDomain="GntR"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00392.24"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory proteins, gntR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5100_0458"
                     /evalue="4.90E-14"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO5100"
                     /locus_tag="SCO5100"
                     /protein_end="71"
                     /protein_start="8"
                     /score="51.9"
                     /tool="antismash"
                     /translation="YLRVAGDLRKKIADGLLPPHTRLPSQARIREEYGVSDTVALEARK
                     VLMAEGLVEGRSGSGTYV"
     misc_feature    46243..46422
                     /gene_synonym="SCBAC28G1.26"
                     /locus_tag="SCO5100"
                     /note="Pfam match to entry PF00392 gntR, Bacterial
                     regulatory proteins, gntR family, score 50.40, E-value
                     5.3e-14"
     PFAM_domain     46540..46935
                     /aSDomain="UTRA"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07702.16"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0006355"
                     /description="UTRA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5100_0459"
                     /evalue="3.80E-13"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO5100"
                     /locus_tag="SCO5100"
                     /protein_end="242"
                     /protein_start="110"
                     /score="49.7"
                     /tool="antismash"
                     /translation="SEQAEASGAVAERLGIKPGDRVMCTRYVFREAGEAVMLSTSWEPL
                     DLTGRTPVMLPEEGPLGGMGVVERMAAIDVVVDNVTEEVGARPGLAEELLALGGVPGHV
                     VLVVQRTFYASGRAVETADVVVPADRYR"
     regulatory      47397..47401
                     /regulatory_class="ribosome_binding_site"
     gene            47408..47599
                     /db_xref="GeneID:1100542"
                     /gene_synonym="SCBAC28G1.27"
                     /locus_tag="SCO5101"
     CDS             47408..47599
                     /codon_start=1
                     /db_xref="GeneID:1100542"
                     /gene_synonym="SCBAC28G1.27"
                     /locus_tag="SCO5101"
                     /note="SCBAC28G1.27, conserved hypothetical protein, len:
                     63 aa; similar to TR:Q9HTF6 (EMBL:AE004953) Pseudomonas
                     aeruginosa hypothetical protein PA5408, 58 aa; fasta
                     scores: opt: 146 Z-score: 225.2 bits: 45.1 E(): 6.2e-05;
                     45.652% identity in 46 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_629251.1"
                     /transl_table=11
                     /translation="MNDSTVTLPWLVFRQDDNGNRYRVGRYATRAEAQEIADTLDGRGH
                     KQLYWVEKLAAPGAGAAD"
     gene            47675..48109
                     /db_xref="GeneID:1100543"
                     /gene_synonym="SCBAC28G1.28"
                     /locus_tag="SCO5102"
     CDS             47675..48109
                     /codon_start=1
                     /db_xref="GeneID:1100543"
                     /gene_synonym="SCBAC28G1.28"
                     /locus_tag="SCO5102"
                     /note="SCBAC28G1.28, possible mutT-like protein, len: 144
                     aa; similar to SW:MUTT_ECOLI (EMBL:X04831) Escherichia coli
                     mutator MutT protein
                     (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.*)
                     MutT, 129 aa; fasta scores: opt: 190 Z-score: 228.6 bits:
                     48.1 E(): 4e-05; 33.333% identity in 132 aa overlap.
                     Contains Pfam match to entry PF00293 mutT, MutT-like domain
                     and match to Prosite entry PS00893 mutT domain signature"
                     /product="mutT-like protein"
                     /protein_id="NP_629252.1"
                     /transl_table=11
                     /translation="MTERIVVGAALLDGGRLLAARRSAPAELAGRWELPGGKVEPGETP
                     EAALVRELREELGVAAEAGGRVPGQWPLRAPFVLQVWTARLRPGSAAPAPLEDHDELRW
                     LTPGQIWDVPWLDQDVPAVERVLAHLGLEAGTGRNGTGPG"
     misc_feature    47681..48061
                     /gene_synonym="SCBAC28G1.28"
                     /locus_tag="SCO5102"
                     /note="Pfam match to entry PF00293 mutT, MutT-like domain,
                     score 85.50, E-value 1.1e-21"
     PFAM_domain     47684..48022
                     /aSDomain="NUDIX"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00293.31"
                     /description="NUDIX domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5102_0460"
                     /evalue="3.30E-18"
                     /label="SCO5102"
                     /locus_tag="SCO5102"
                     /protein_end="116"
                     /protein_start="3"
                     /score="66.1"
                     /tool="antismash"
                     /translation="RIVVGAALLDGGRLLAARRSAPAELAGRWELPGGKVEPGETPEAA
                     LVRELREELGVAAEAGGRVPGQWPLRAPFVLQVWTARLRPGSAAPAPLEDHDELRWLTP
                     GQIWDVPWL"
     misc_feature    47783..47842
                     /gene_synonym="SCBAC28G1.28"
                     /locus_tag="SCO5102"
                     /note="PS00893 mutT domain signature"
     gene            48148..48615
                     /db_xref="GeneID:1100544"
                     /gene_synonym="SCBAC28G1.29"
                     /locus_tag="SCO5103"
     CDS             48148..48615
                     /codon_start=1
                     /db_xref="GeneID:1100544"
                     /gene_synonym="SCBAC28G1.29"
                     /locus_tag="SCO5103"
                     /note="SCBAC28G1.29, possible regulatory protein, len: 155
                     aa; similar to TR:Q53897 (EMBL:X60316) Streptomyces
                     coelicolor AbaA gene (regulator) or SCF42.12c, 192 aa;
                     fasta scores: opt: 207 Z-score: 233.7 bits: 49.7 E():
                     2.1e-05; 41.270% identity in 126 aa overlap. Contains Pfam
                     match to entry PF02518 HATPase_c, Histidine kinase-, DNA
                     gyrase B-, phytochrome-like ATPase"
                     /product="regulatory protein"
                     /protein_id="NP_629253.1"
                     /transl_table=11
                     /translation="MGSSAGEVIGVKDGEGDCAEWVFPAAPDAVRTARSLVRRTLGEWR
                     LDSVGDIAALLVSELVTNALRHATGPIGVRLVRSPAPAAPAAGGAGGDGADGVLLVEVS
                     DPLPDPPRERVARPDDEDGRGLQLVASAARRWGTRPGEAGKTVWFELALPR"
     misc_feature    48295..48462
                     /gene_synonym="SCBAC28G1.29"
                     /locus_tag="SCO5103"
                     /note="Pfam match to entry PF02518 HATPase_c, Histidine
                     kinase-, DNA gyrase B-, phytochrome-like ATPase, score
                     10.00, E-value 0.22"
     regulatory      48899..48903
                     /regulatory_class="ribosome_binding_site"
     gene            48915..51557
                     /db_xref="GeneID:1100545"
                     /gene_synonym="SCBAC28G1.30"
                     /locus_tag="SCO5104"
     CDS             48915..51557
                     /codon_start=1
                     /db_xref="GeneID:1100545"
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /gene_synonym="SCBAC28G1.30"
                     /locus_tag="SCO5104"
                     /note="SCBAC28G1.30, hypothetical protein, len: 880 aa;
                     similar to many Streptomyces coelicolor hypothetical
                     proteins, e.g. TR:Q9KYN1 (EMBL:AL356592) hypothetical 84.7
                     kDa protein SC9H11.08, 802 aa; fasta scores: opt: 1062
                     Z-score: 1155.9 bits: 224.9 E(): 9.1e-57; 38.902% identity
                     in 856 aa overlap. Contains 2x Pfam matches, Pfam match to
                     entry PF01590 GAF, GAF domain, to entry PF00989 PAS, PAS
                     domain and to entry PF02518 HATPase_c, Histidine kinase-,
                     DNA gyrase B-, phytochrome-like ATPase"
                     /product="hypothetical protein"
                     /protein_id="NP_629254.1"
                     /transl_table=11
                     /translation="MSEIPARAKEPTESTESGGPSADAPLGDAVWQSSPPGSIYDYIKV
                     ASFSIGPDGLVDQWSLRAEQLLGIRAEDAVGSDPIEAFIDPDLRERGQRKMTEILDGRE
                     WTGVVPFRAPDEAEGTARHASGRPADGPPTGGRPGQRGLAEVYVMPTRTEDGEKAAVCI
                     VVDVRVLRSIETDLAASQAIFGQSPFGFLLIDPDLTVRRANQRFASIFGGTPDDHRGKG
                     VHDYLPRAEADRVCATLRRVLETGDSITDMHVTGFVPGSEERRHWSVNLYRVHSGSGRP
                     IGVAWLGTDITARRQAAREAANARRNLALLNEAGARIGNSLDLETTARELLDVVVPGFC
                     DLATVDLYQGLLVGDETPPGLADGSAELRRVAFSSAVSDAPFLGTGERVKLGAVHHYPF
                     NSPCADALRTARPRSVPAEDGGLVQSTLAVPMVAHDTVVGLVQFARTKGSEPFGDRDRD
                     LAVELAARAAVCIDNARLYRREHERALILQRSLLPPGDPEASGLDIACRYLPGEAATGR
                     ASEVGGDWFDVIELPGHRTALVVGDVMGRGLRAAVAMGELRTAVRTLAQLDIEPAEVLS
                     QLDEIARGLGAPGGVQQATRAARRPREADLSEVYLATCVYAVYDSVTRRCTFANAGHLP
                     PVLVEPGESALMLDVPPGLPLGVGGEPFEEVEVELPEGALLALYTDGLVESRDHPLDEG
                     LQAFVGALTDPTQPLEDVCDQVLNTLDSHHGEDDIALLMARVQGLPADSVGDWTLPREP
                     RSVGRAREYARAQLLAWDMEPLVDTTELLVSELVTNALRYGEGEIRLRLLLDRTLVCEV
                     WDSGLVQPRRRRARDTDEGGRGLQLVGLLSAAWGSRRTPRGKTVWFELPLPGADTQLTD
                     PAEALLSLF"
     aSDomain        49026..49229
                     /aSDomain="TIGR00229"
                     /aSTool="tigrfam"
                     /description="sensory_box: PAS domain S-box protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5104_0051"
                     /evalue="8.50E-06"
                     /identifier="TIGR00229"
                     /label="SCO5104"
                     /locus_tag="SCO5104"
                     /protein_end="105"
                     /protein_start="37"
                     /score="23.9"
                     /tool="antismash"
                     /translation="SIYDYIKVASFSIGPDGLVDQWSLRAEQLLGIRAEDAVGSDPIEA
                     FIDPDLRERGQRKMTEILDGREW"
     misc_feature    49041..49211
                     /gene_synonym="SCBAC28G1.30"
                     /locus_tag="SCO5104"
                     /note="Pfam match to entry PF00989 PAS, PAS domain, score
                     9.80, E-value 0.44"
     misc_feature    49446..49640
                     /gene_synonym="SCBAC28G1.30"
                     /locus_tag="SCO5104"
                     /note="Pfam match to entry PF00989 PAS, PAS domain, score
                     15.70, E-value 0.0098"
     aSDomain        49455..49814
                     /aSDomain="TIGR00229"
                     /aSTool="tigrfam"
                     /description="sensory_box: PAS domain S-box protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5104_0052"
                     /evalue="5.60E-08"
                     /identifier="TIGR00229"
                     /label="SCO5104"
                     /locus_tag="SCO5104"
                     /protein_end="300"
                     /protein_start="180"
                     /score="30.9"
                     /tool="antismash"
                     /translation="QAIFGQSPFGFLLIDPDLTVRRANQRFASIFGGTPDDHRGKGVHD
                     YLPRAEADRVCATLRRVLETGDSITDMHVTGFVPGSEERRHWSVNLYRVHSGSGRPIGV
                     AWLGTDITARRQAARE"
     PFAM_domain     49467..49802
                     /aSDomain="PAS_4"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08448.13"
                     /description="PAS fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5104_0461"
                     /evalue="1.10E-26"
                     /label="SCO5104"
                     /locus_tag="SCO5104"
                     /protein_end="296"
                     /protein_start="184"
                     /score="93.3"
                     /tool="antismash"
                     /translation="GQSPFGFLLIDPDLTVRRANQRFASIFGGTPDDHRGKGVHDYLPR
                     AEADRVCATLRRVLETGDSITDMHVTGFVPGSEERRHWSVNLYRVHSGSGRPIGVAWLG
                     TDITARRQ"
     misc_feature    49881..50342
                     /gene_synonym="SCBAC28G1.30"
                     /locus_tag="SCO5104"
                     /note="Pfam match to entry PF01590 GAF, GAF domain, score
                     42.60, E-value 8.6e-09"
     PFAM_domain     50115..50327
                     /aSDomain="GAF"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01590.29"
                     /db_xref="GO:0005515"
                     /description="GAF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5104_0462"
                     /evalue="5.40E-06"
                     /gene_ontologies="GO:0005515: protein binding"
                     /label="SCO5104"
                     /locus_tag="SCO5104"
                     /protein_end="471"
                     /protein_start="400"
                     /score="27.2"
                     /tool="antismash"
                     /translation="SPCADALRTARPRSVPAEDGGLVQSTLAVPMVAHDTVVGLVQFAR
                     TKGSEPFGDRDRDLAVELAARAAVCI"
     PFAM_domain     50508..51125
                     /aSDomain="SpoIIE"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07228.15"
                     /description="Stage II sporulation protein E (SpoIIE)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5104_0463"
                     /evalue="4.90E-52"
                     /label="SCO5104"
                     /locus_tag="SCO5104"
                     /protein_end="737"
                     /protein_start="531"
                     /score="176.8"
                     /tool="antismash"
                     /translation="PGHRTALVVGDVMGRGLRAAVAMGELRTAVRTLAQLDIEPAEVLS
                     QLDEIARGLGAPGGVQQATRAARRPREADLSEVYLATCVYAVYDSVTRRCTFANAGHLP
                     PVLVEPGESALMLDVPPGLPLGVGGEPFEEVEVELPEGALLALYTDGLVESRDHPLDEG
                     LQAFVGALTDPTQPLEDVCDQVLNTLDSHHGEDDIALLMARVQ"
     PFAM_domain     51162..51488
                     /aSDomain="HATPase_c_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13581.9"
                     /description="Histidine kinase-like ATPase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5104_0464"
                     /evalue="7.30E-07"
                     /label="SCO5104"
                     /locus_tag="SCO5104"
                     /protein_end="858"
                     /protein_start="749"
                     /score="29.3"
                     /tool="antismash"
                     /translation="PREPRSVGRAREYARAQLLAWDMEPLVDTTELLVSELVTNALRYG
                     EGEIRLRLLLDRTLVCEVWDSGLVQPRRRRARDTDEGGRGLQLVGLLSAAWGSRRTPRG
                     KTVWF"
     misc_feature    51258..51362
                     /gene_synonym="SCBAC28G1.30"
                     /locus_tag="SCO5104"
                     /note="Pfam match to entry PF02518 HATPase_c, Histidine
                     kinase-, DNA gyrase B-, phytochrome-like ATPase, score
                     9.60, E-value 0.28"
     misc_feature    51662..51675
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     regulatory      51787..51791
                     /regulatory_class="ribosome_binding_site"
     gene            51799..53031
                     /db_xref="GeneID:1100546"
                     /gene_synonym="SCBAC31E11.01"
                     /locus_tag="SCO5105"
     CDS             51799..53031
                     /codon_start=1
                     /db_xref="GeneID:1100546"
                     /gene_synonym="SCBAC31E11.01"
                     /locus_tag="SCO5105"
                     /note="SCBAC31E11.01, possible membrane protein, len: 410
                     aa. Contains possible hydrophobic membrane spanning region"
                     /product="hypothetical protein"
                     /protein_id="NP_629255.1"
                     /transl_table=11
                     /translation="MADTEPGNTEPRSTEPGNTELRSTEPGSIEPGSTEPEAADGEDGP
                     PGPPASDDESGTGGAGGNRDAEGEAEATRRTRRRTRIRRTAVAVLLVLLVPLLTAETAL
                     RVNYMGDPADGTHTRNRDAMWLGHAWVDGRKDDADLAAFARRVKATGIRDLYVHTGPME
                     HDGTLPKSLYPRARWLVGAVHRELPGVRVQAFLGDVLATESPDGMRLEKPATRAAVVGS
                     ARQVLDVGYDGVHLDLEPLHSGDGDYLSLLDDVRAVTRARDAQLSVAAHQIDPLPGFHS
                     FWGTVAGHPKWWSQEFFGQVARRVDQIAVMSYDTMQPLESLYGGYVAQQTSLALEVTPP
                     TTHLLMGLPFYHENRFGHWNHAETVAAAVRGVRLGLSRTDADRERFGVAAYIDFAATEQ
                     DWASYRDGWVR"
     gene            complement(53028..53807)
                     /db_xref="GeneID:1100547"
                     /gene_synonym="SCBAC31E11.02c; shdB2"
                     /locus_tag="SCO5106"
     CDS             complement(53028..53807)
                     /codon_start=1
                     /db_xref="GeneID:1100547"
                     /gene_synonym="SCBAC31E11.02c; shdB2"
                     /locus_tag="SCO5106"
                     /note="catalyzes the fumarate and succinate
                     interconversion; fumarate reductase is used under anaerobic
                     conditions with glucose or glycerol as carbon source"
                     /product="fumarate reductase iron-sulfur subunit"
                     /protein_id="NP_629256.1"
                     /transl_table=11
                     /translation="MSGYEARFKVWRGDVAGGGLEDFTVEVNDGEVVLDIIHRLQATQA
                     PDLAVRWNCKAGKCGSCSAEINGRPRLLCMTRMSVFTREETITVTPLRAFPVIRDLVTD
                     VGFNYTKAREVPAFVPPADLGPGEYRMMQEDVDRSQEFRKCIECFLCQDTCHVVRDHEE
                     NKPAFAGPRFLMRVAELDMHPLDAAGDTGLDRSRTAQDEHGLGFCNITKCCTEVCPEGI
                     RITDNALIPLKERAVDRKYDPLVWLGAKIGRRSRDTP"
     aSDomain        complement(53133..53750)
                     /aSDomain="TIGR00384"
                     /aSTool="tigrfam"
                     /description="dhsB: succinate dehydrogenase and fumarate
                     reductase iron-sulfur protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5106_0053"
                     /evalue="2.00E-42"
                     /identifier="TIGR00384"
                     /label="SCO5106"
                     /locus_tag="SCO5106"
                     /protein_end="225"
                     /protein_start="19"
                     /score="143.1"
                     /tool="antismash"
                     /translation="LEDFTVEVNDGEVVLDIIHRLQATQAPDLAVRWNCKAGKCGSCSA
                     EINGRPRLLCMTRMSVFTREETITVTPLRAFPVIRDLVTDVGFNYTKAREVPAFVPPAD
                     LGPGEYRMMQEDVDRSQEFRKCIECFLCQDTCHVVRDHEENKPAFAGPRFLMRVAELDM
                     HPLDAAGDTGLDRSRTAQDEHGLGFCNITKCCTEVCPEGIRIT"
     PFAM_domain     complement(53142..53387)
                     /aSDomain="Fer4_8"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13183.9"
                     /description="4Fe-4S dicluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5106_0466"
                     /evalue="2.40E-14"
                     /label="SCO5106"
                     /locus_tag="SCO5106"
                     /protein_end="222"
                     /protein_start="140"
                     /score="53.6"
                     /tool="antismash"
                     /translation="EFRKCIECFLCQDTCHVVRDHEENKPAFAGPRFLMRVAELDMHPL
                     DAAGDTGLDRSRTAQDEHGLGFCNITKCCTEVCPEGI"
     PFAM_domain     complement(53493..53756)
                     /aSDomain="Fer2_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13085.9"
                     /db_xref="GO:0009055"
                     /db_xref="GO:0051536"
                     /description="2Fe-2S iron-sulfur cluster binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5106_0465"
                     /evalue="6.00E-24"
                     /gene_ontologies="GO:0009055: electron transfer activity"
                     /gene_ontologies="GO:0051536: iron-sulfur cluster binding"
                     /label="SCO5106"
                     /locus_tag="SCO5106"
                     /protein_end="105"
                     /protein_start="17"
                     /score="84.3"
                     /tool="antismash"
                     /translation="GGLEDFTVEVNDGEVVLDIIHRLQATQAPDLAVRWNCKAGKCGSC
                     SAEINGRPRLLCMTRMSVFTREETITVTPLRAFPVIRDLVTDV"
     misc_feature    complement(53568..53750)
                     /gene_synonym="SCBAC31E11.02c; shdB2"
                     /locus_tag="SCO5106"
                     /note="Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur
                     cluster binding domains, score 35.00, E-value 1.7e-06"
     gene            complement(53804..55765)
                     /db_xref="GeneID:1100548"
                     /gene="sdhA"
                     /gene_synonym="SCBAC31E11.02c; shdA2"
                     /locus_tag="SCO5107"
     CDS             complement(53804..55765)
                     /EC_number="1.3.5.1"
                     /codon_start=1
                     /db_xref="GeneID:1100548"
                     /gene="sdhA"
                     /gene_synonym="SCBAC31E11.02c; shdA2"
                     /locus_tag="SCO5107"
                     /note="part of four member succinate dehydrogenase enzyme
                     complex that forms a trimeric complex (trimer of
                     tetramers); SdhA/B are the catalytic subcomplex and can
                     exhibit succinate dehydrogenase activity in the absence of
                     SdhC/D which are the membrane components and form
                     cytochrome b556; SdhC binds ubiquinone; oxidizes succinate
                     to fumarate while reducing ubiquinone to ubiquinol"
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="NP_629257.1"
                     /transl_table=11
                     /translation="MSVVDRQEWDVVVVGAGGAGLRAAVEARERGARTAVICKSLFGKA
                     HTVMAEGGIAASMGNVNSGDNWQVHFRDTMRGGKFLNQWRMAELHAQEAPQRVWELETW
                     GALFDRTKDGRISQRNFGGHEYPRLAHVGDRTGLELIRTLQQKIVSLQQEDFRETGDHE
                     SRLKVFQECTVTRLLQEDRKVSGVFGYERESGRFFVLQAPSVVIATGGIGKSFKVTSNS
                     WEYTGDGHALALLAGAPLLNMEFVQFHPTGMVWPPSVKGILVTESVRGDGGVLRNSEGR
                     RFMFDYVPDVFKEKYAESEAEGDRWYDDPDHNRRPPELLPRDEVARAINAEVKEGRGSP
                     HGGVFLDVSTRMPAEVIRRRLPSMYHQFKELADVDITAEAMEVGPTCHYVMGGIAVDSD
                     TAAARGVPGLFAAGEVAGGMHGSNRLGGNSLSDLLVFGRRAGRYAAEYAAGRTEEGTRA
                     RVDDAQVDAAAAEALRPFSAEAQEPGAGPPENPYTLHQELQQTMNDLVGIIRREAEMKQ
                     ALEKLAELRVRARRAGVEGHRQFNPGWHLALDLRNMLLVSECVARAALERTESRGGHTR
                     EDHPSMDRRWRPANLLCSLADPAGEAAGEAAATDPERGRIALERQTTEPIRPDLLALFD
                     KEELVKYLADEELEGRSE"
     regulatory      complement(53818..53822)
                     /gene="sdhA"
                     /gene_synonym="SCBAC31E11.02c; shdA2"
                     /locus_tag="SCO5107"
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(53969..54283)
                     /gene="sdhA"
                     /gene_synonym="SCBAC31E11.02c; shdA2"
                     /locus_tag="SCO5107"
                     /note="Pfam match to entry PF02910 succ_DH_flav_C, Fumarate
                     reductase/succinate dehydrogenase flavoprotein C-terminal
                     domain, score 69.20, E-value 8.9e-17"
     PFAM_domain     complement(53993..54283)
                     /aSDomain="Succ_DH_flav_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02910.23"
                     /db_xref="GO:0016491"
                     /description="Fumarate reductase flavoprotein C-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5107_0468"
                     /evalue="8.70E-25"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO5107"
                     /locus_tag="SCO5107"
                     /protein_end="591"
                     /protein_start="494"
                     /score="87.2"
                     /tool="antismash"
                     /translation="HQELQQTMNDLVGIIRREAEMKQALEKLAELRVRARRAGVEGHRQ
                     FNPGWHLALDLRNMLLVSECVARAALERTESRGGHTREDHPSMDRRWRPANL"
     misc_feature    complement(54362..55438)
                     /gene="sdhA"
                     /gene_synonym="SCBAC31E11.02c; shdA2"
                     /locus_tag="SCO5107"
                     /note="Pfam match to entry PF00890 FAD_binding_2, FAD
                     binding domain, score 404.30, E-value 1.2e-117"
     PFAM_domain     complement(54476..55738)
                     /aSDomain="FAD_binding_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00890.27"
                     /description="FAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5107_0467"
                     /evalue="4.30E-93"
                     /label="SCO5107"
                     /locus_tag="SCO5107"
                     /protein_end="430"
                     /protein_start="9"
                     /score="312.8"
                     /tool="antismash"
                     /translation="DVVVVGAGGAGLRAAVEARERGARTAVICKSLFGKAHTVMAEGGI
                     AASMGNVNSGDNWQVHFRDTMRGGKFLNQWRMAELHAQEAPQRVWELETWGALFDRTKD
                     GRISQRNFGGHEYPRLAHVGDRTGLELIRTLQQKIVSLQQEDFRETGDHESRLKVFQEC
                     TVTRLLQEDRKVSGVFGYERESGRFFVLQAPSVVIATGGIGKSFKVTSNSWEYTGDGHA
                     LALLAGAPLLNMEFVQFHPTGMVWPPSVKGILVTESVRGDGGVLRNSEGRRFMFDYVPD
                     VFKEKYAESEAEGDRWYDDPDHNRRPPELLPRDEVARAINAEVKEGRGSPHGGVFLDVS
                     TRMPAEVIRRRLPSMYHQFKELADVDITAEAMEVGPTCHYVMGGIAVDSDTAAARGVPG
                     LFAAGEVAGGMHGSNRLGGNSL"
     misc_feature    complement(55121..55144)
                     /gene="sdhA"
                     /gene_synonym="SCBAC31E11.02c; shdA2"
                     /locus_tag="SCO5107"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     regulatory      complement(55773..55776)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(55782..56618)
                     /db_xref="GeneID:1100549"
                     /gene_synonym="SCBAC31E11.04c"
                     /locus_tag="SCO5108"
     CDS             complement(55782..56618)
                     /codon_start=1
                     /db_xref="GeneID:1100549"
                     /gene_synonym="SCBAC31E11.04c"
                     /locus_tag="SCO5108"
                     /note="SCBAC31E11.04c, possible integral membrane protein,
                     len: 278 aa; similar to TR:O53671 (EMBL:AL021929)
                     Mycobacterium tuberculosis hypothetical 31.1 kDa protein
                     MTV034.15c, 273 aa; fasta scores: opt: 1010 Z-score: 1230.3
                     bits: 235.4 E(): 6.5e-61; 54.545% identity in 275 aa
                     overlap. Contains possible hydrophobic membrane spanning
                     regions"
                     /product="hypothetical protein"
                     /protein_id="NP_629258.1"
                     /transl_table=11
                     /translation="MATGTEPPATEDRPPGGGVHTPTRAAIRARHLRTDRWWLAPAATA
                     AGLLAFVVYSTWRAFANADYYAAPYVSPFYSPCLAENCEPMRSGPNWELFGTWWGISPA
                     IIILIFPLGFRLTCYYYRKAYYRGFWASPPACAVAEPHRKYTGETRFPLILQNVHRYFF
                     YAALLVAGILSYDTVLAFRDEHYAWGHMGLGTLVFLANIALIWAYTLSCHSCRHIVGGK
                     LKHFSRHPVRYRMWQLVGRLNARHMQLAWASLVSVALADFYVYLVASGVFDDPRFF"
     regulatory      complement(56626..56629)
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(56646..56664)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.15"
                     /tool="antismash"
     gene            complement(56680..57120)
                     /db_xref="GeneID:1100550"
                     /gene_synonym="SCBAC31E11.05c"
                     /locus_tag="SCO5109"
     CDS             complement(56680..57120)
                     /codon_start=1
                     /db_xref="GeneID:1100550"
                     /gene_synonym="SCBAC31E11.05c"
                     /locus_tag="SCO5109"
                     /note="SCBAC31E11.05c, unknown, len: 146 aa. Contains a
                     possible coiled-coil region at approx. residues 60..87"
                     /product="hypothetical protein"
                     /protein_id="NP_629259.1"
                     /transl_table=11
                     /translation="MPPAVHRRAPANRCTSLPSDWCDARHSQAHERSPPRPAAHCRVRR
                     KRGHVLSVHDDLSSVQRSLDELSRTVTRLEQQLGSGDLEVRRVRTDADHLRESVALLRA
                     ATAAPQAPRRPDLVPIPDTPYDGSLWTDSDDEGLGARDRRAP"
     misc_feature    57219..57233
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.74"
                     /tool="antismash"
     regulatory      57280..57285
                     /regulatory_class="ribosome_binding_site"
     gene            57293..59608
                     /db_xref="GeneID:1100551"
                     /gene_synonym="SCBAC31E11.06"
                     /locus_tag="SCO5110"
     CDS             57293..59608
                     /codon_start=1
                     /db_xref="GeneID:1100551"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /gene_synonym="SCBAC31E11.06"
                     /locus_tag="SCO5110"
                     /note="SCBAC31E11.06, possible lipoprotein, len: 771 aa;
                     similar to SW:YC80_MYCTU (EMBL:Z77137) Mycobacterium
                     tuberculosis hypothetical 63.5 kDa protein MTCY50.02, 591
                     aa; fasta scores: opt: 565 Z-score: 501.6 bits: 103.2 E():
                     2.5e-20; 26.190% identity in 756 aa overlap. Contains
                     correctly situated match to Prosite entry PS00013
                     Prokaryotic membrane lipoprotein lipid attachment site and
                     possible N-terminal region signal peptide sequence"
                     /product="lipoprotein"
                     /protein_id="NP_629260.1"
                     /transl_table=11
                     /translation="MSHVGVGPRAVMRAVAFLTTGVLAVPALAGCTSEDPAGKPLAEQD
                     VAAAARARISDGGTLRWAVDSVPDTLNAFQSDADATTTRVAQAVLPSMYRMDETGSPVR
                     NPDYLESAEVVDTEPKQVVVYKLNQQAVWSDGREIGAADFAAQWRALSGKDSAYWTARN
                     AGYDRIEKVERGANDLEVKVTFSRPYADWKALFTPLYPKDVTGTPDAFNDGARRALKVS
                     AGPFAVKKVDTKGDQVVLTGNPRWWGEPAKLDEIVLRAVPRDERVSELVAGKLDLAEID
                     PETADEVTLAAGPRDPATGTPLMGPGGTPAAGPQGRSAAEALRSWAIANGSDEEAAEEE
                     VLAREERGEAEAKARRRQQALSGFELRKSLEPAYTQLALNGAEGPLADERVRRAVARAL
                     DREELAEAVLKPLGLPAEPVGSHLALSGQPAYADGSGALGEQNAKEARALLADAGWVPG
                     GPVKKKDGEEAAGAEKDENKDEDKKDEEKSEGGDDGTYIVGEDDKNKDGKNKDGKNDDG
                     KNDDGGNDDGGNDDAGDAKDGADRESGEKHSSGKNTAQGGAPGAYAPKGTAAPAGAAAA
                     PLAKDGKELTLRFVLPSGPGSGTLRTVADRITDMLKEIGIGTRITKVPDESYFKDHIAA
                     GEYDLALYSWPASAFPATDARPIYAKPVPAADGSLNVAQNYTRVGTDQVDQLFDRALAT
                     LDQKESRDLLRKADSRIWAAAGSVPLYQRPQLTAARKNLANAGAFGFGTPVYEDMGFLK
                     KGAQGSRPTAPASPSPSS"
     misc_feature    57353..57385
                     /gene_synonym="SCBAC31E11.06"
                     /locus_tag="SCO5110"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site"
     PFAM_domain     57611..58168
                     /aSDomain="SBP_bac_5"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00496.25"
                     /description="Bacterial extracellular solute-binding
                     proteins, family 5 Middle"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5110_0469"
                     /evalue="1.60E-23"
                     /label="SCO5110"
                     /locus_tag="SCO5110"
                     /protein_end="292"
                     /protein_start="106"
                     /score="83.5"
                     /tool="antismash"
                     /translation="DYLESAEVVDTEPKQVVVYKLNQQAVWSDGREIGAADFAAQWRAL
                     SGKDSAYWTARNAGYDRIEKVERGANDLEVKVTFSRPYADWKALFTPLYPKDVTGTPDA
                     FNDGARRALKVSAGPFAVKKVDTKGDQVVLTGNPRWWGEPAKLDEIVLRAVPRDERVSE
                     LVAGKLDLAEIDPETADEVTLAA"
     PFAM_domain     58364..58672
                     /aSDomain="SBP_bac_5"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00496.25"
                     /description="Bacterial extracellular solute-binding
                     proteins, family 5 Middle"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5110_0470"
                     /evalue="3.10E-13"
                     /label="SCO5110"
                     /locus_tag="SCO5110"
                     /protein_end="460"
                     /protein_start="357"
                     /score="49.6"
                     /tool="antismash"
                     /translation="QQALSGFELRKSLEPAYTQLALNGAEGPLADERVRRAVARALDRE
                     ELAEAVLKPLGLPAEPVGSHLALSGQPAYADGSGALGEQNAKEARALLADAGWVPGGP"
     misc_feature    58676..58753
                     /gene_synonym="SCBAC31E11.06"
                     /locus_tag="SCO5110"
                     /note="high content in lysine, glutamic acid and aspartic
                     acid amino acid residues"
     misc_feature    58793..58912
                     /gene_synonym="SCBAC31E11.06"
                     /locus_tag="SCO5110"
                     /note="high content in aspartic acid, asparagine, glycine
                     and lysine amino acid residues"
     regulatory      59727..59730
                     /regulatory_class="ribosome_binding_site"
     gene            59741..61648
                     /db_xref="GeneID:1100552"
                     /gene_synonym="SCBAC31E11.07"
                     /locus_tag="SCO5111"
     CDS             59741..61648
                     /codon_start=1
                     /db_xref="GeneID:1100552"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCBAC31E11.07"
                     /locus_tag="SCO5111"
                     /note="SCBAC31E11.07, possible GTP-binding protein, len:
                     635 aa; similar to SW:TYPA_ECOLI (EMBL:L19201) Escherichia
                     coli GTP-binding protein TypA/BipA (tyrosine phosphorylated
                     protein A) TypA or BipA or B3871, 591 aa; fasta scores:
                     opt: 915 Z-score: 968.6 bits: 189.3 E(): 2.5e-46; 48.039%
                     identity in 612 aa overlap. Contains Pfam match to entry
                     PF00009 GTP_EFTU, Elongation factor Tu family and matches
                     to Prosite entries PS00017 ATP/GTP-binding site motif A
                     (P-loop) and PS00301 GTP-binding elongation factors
                     signature"
                     /product="GTP-binding protein"
                     /protein_id="NP_629261.1"
                     /transl_table=11
                     /translation="MATRHDIRNVAIVAHVDHGKTTIVDGMLKQAGAFAAHQLEGVDDR
                     MMDSNDLEREKGITILAKNTAVKYHPKDGGDVITINIIDTPGHADFGGEVERGLSMVDG
                     VVLLVDASEGPLPQTRFVLRKALSQRLPIILCINKTDRPDARIDEVVNETYDLFLDLDA
                     DEEQIEFPIVYACGRDGVASLTKPEDGTVPSDSTSLEPFFSTILDHIPAPTYDEDAPLQ
                     AHVTNLDADNFLGRIALLRVHQGELKKGQTVAWMKRDGSVQNVRISELMMTEALTRKPA
                     EKAGPGDICAVAGIPDIMIGETLADVENPVPLPLITVDEPAISMTIGTNTSPLVGRGAT
                     GKGADNKAVVKDRKVTARQVKDRLDRELIGNVSLRVLDTERPDAWEVQGRGELALAILV
                     EQMRREGFELTIGKPQVVTKEVEGKTYEPVERMTIDVPEEHMGAVTQLMGVRKGRMDNM
                     SNHGSGWVRMEFVVPSRGLIGFRTEFLTQTRGTGIAHSIHEGHEPWFGTLTTRNNGSLV
                     ADRSGAVTAFAMTNLQERGVLFTDPGTEVYEGMIVGENSRADDMDVNITKEKKLTNMRS
                     SSADSFEAIVPPRKLSLEQSLEFCRDDECVEVTPEAVRIRKVNLDARERARAASRAKHG
                     "
     misc_feature    59753..61003
                     /gene_synonym="SCBAC31E11.07"
                     /locus_tag="SCO5111"
                     /note="Pfam match to entry PF00009 GTP_EFTU, Elongation
                     factor Tu family, score 320.10, E-value 2.7e-92"
     PFAM_domain     59756..60373
                     /aSDomain="GTP_EFTU"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00009.30"
                     /db_xref="GO:0003924"
                     /db_xref="GO:0005525"
                     /description="Elongation factor Tu GTP binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5111_0471"
                     /evalue="1.90E-51"
                     /gene_ontologies="GO:0003924: GTPase activity"
                     /gene_ontologies="GO:0005525: GTP binding"
                     /label="SCO5111"
                     /locus_tag="SCO5111"
                     /protein_end="211"
                     /protein_start="5"
                     /score="174.5"
                     /tool="antismash"
                     /translation="DIRNVAIVAHVDHGKTTIVDGMLKQAGAFAAHQLEGVDDRMMDSN
                     DLEREKGITILAKNTAVKYHPKDGGDVITINIIDTPGHADFGGEVERGLSMVDGVVLLV
                     DASEGPLPQTRFVLRKALSQRLPIILCINKTDRPDARIDEVVNETYDLFLDLDADEEQI
                     EFPIVYACGRDGVASLTKPEDGTVPSDSTSLEPFFSTILDHIP"
     aSDomain        59759..60217
                     /aSDomain="TIGR00231"
                     /aSTool="tigrfam"
                     /description="small_GTP: small GTP-binding protein domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5111_0055"
                     /evalue="1.50E-22"
                     /identifier="TIGR00231"
                     /label="SCO5111"
                     /locus_tag="SCO5111"
                     /protein_end="159"
                     /protein_start="6"
                     /score="78.1"
                     /tool="antismash"
                     /translation="IRNVAIVAHVDHGKTTIVDGMLKQAGAFAAHQLEGVDDRMMDSND
                     LEREKGITILAKNTAVKYHPKDGGDVITINIIDTPGHADFGGEVERGLSMVDGVVLLVD
                     ASEGPLPQTRFVLRKALSQRLPIILCINKTDRPDARIDEVVNETYDLFL"
     aSDomain        59759..61621
                     /aSDomain="TIGR01394"
                     /aSTool="tigrfam"
                     /description="TypA_BipA: GTP-binding protein TypA/BipA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5111_0054"
                     /evalue="2.00E-289"
                     /identifier="TIGR01394"
                     /label="SCO5111"
                     /locus_tag="SCO5111"
                     /protein_end="627"
                     /protein_start="6"
                     /score="958.8"
                     /tool="antismash"
                     /translation="IRNVAIVAHVDHGKTTIVDGMLKQAGAFAAHQLEGVDDRMMDSND
                     LEREKGITILAKNTAVKYHPKDGGDVITINIIDTPGHADFGGEVERGLSMVDGVVLLVD
                     ASEGPLPQTRFVLRKALSQRLPIILCINKTDRPDARIDEVVNETYDLFLDLDADEEQIE
                     FPIVYACGRDGVASLTKPEDGTVPSDSTSLEPFFSTILDHIPAPTYDEDAPLQAHVTNL
                     DADNFLGRIALLRVHQGELKKGQTVAWMKRDGSVQNVRISELMMTEALTRKPAEKAGPG
                     DICAVAGIPDIMIGETLADVENPVPLPLITVDEPAISMTIGTNTSPLVGRGATGKGADN
                     KAVVKDRKVTARQVKDRLDRELIGNVSLRVLDTERPDAWEVQGRGELALAILVEQMRRE
                     GFELTIGKPQVVTKEVEGKTYEPVERMTIDVPEEHMGAVTQLMGVRKGRMDNMSNHGSG
                     WVRMEFVVPSRGLIGFRTEFLTQTRGTGIAHSIHEGHEPWFGTLTTRNNGSLVADRSGA
                     VTAFAMTNLQERGVLFTDPGTEVYEGMIVGENSRADDMDVNITKEKKLTNMRSSSADSF
                     EAIVPPRKLSLEQSLEFCRDDECVEVTPEAVRIRKVNLDARERAR"
     misc_feature    59780..59803
                     /gene_synonym="SCBAC31E11.07"
                     /locus_tag="SCO5111"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     misc_feature    59882..59929
                     /gene_synonym="SCBAC31E11.07"
                     /locus_tag="SCO5111"
                     /note="PS00301 GTP-binding elongation factors signature"
     PFAM_domain     60443..60655
                     /aSDomain="GTP_EFTU_D2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03144.28"
                     /db_xref="GO:0005525"
                     /description="Elongation factor Tu domain 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5111_0472"
                     /evalue="2.40E-11"
                     /gene_ontologies="GO:0005525: GTP binding"
                     /label="SCO5111"
                     /locus_tag="SCO5111"
                     /protein_end="305"
                     /protein_start="234"
                     /score="44.0"
                     /tool="antismash"
                     /translation="GRIALLRVHQGELKKGQTVAWMKRDGSVQNVRISELMMTEALTRK
                     PAEKAGPGDICAVAGIPDIMIGETLA"
     PFAM_domain     61013..61255
                     /aSDomain="EFG_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00679.27"
                     /description="Elongation factor G C-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5111_0473"
                     /evalue="4.60E-20"
                     /label="SCO5111"
                     /locus_tag="SCO5111"
                     /protein_end="505"
                     /protein_start="424"
                     /score="71.6"
                     /tool="antismash"
                     /translation="TYEPVERMTIDVPEEHMGAVTQLMGVRKGRMDNMSNHGSGWVRME
                     FVVPSRGLIGFRTEFLTQTRGTGIAHSIHEGHEPWF"
     stem_loop       61657..61713
                     /note="possible stem loop. Score 64: 24/26 (92%) matches, 0
                     gaps"
     misc_feature    62129..68508
                     /note="previously sequenced DNA fragment. EMBL:U68036
                     Streptomyces coelicolor bldKA, bldKB, bldKC, and bldkD
                     genes, complete cds, and bldkE gene, partial cds"
     gene            62555..63586
                     /db_xref="GeneID:1100553"
                     /gene_synonym="bldKA; SCBAC31E11.08"
                     /locus_tag="SCO5112"
     CDS             62555..63586
                     /codon_start=1
                     /db_xref="GeneID:1100553"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /gene_synonym="bldKA; SCBAC31E11.08"
                     /locus_tag="SCO5112"
                     /note="SCBAC31E11.08, bldKA, possible ABC transport system
                     integral membrane protein, len: 343 aa; identical to
                     previously sequenced TR:P72406 (EMBL:U68036) Streptomyces
                     coelicolor BldKA, 335 aa. Methionine start codon 9 amino
                     acids upstream from the previous sequence start; possible
                     frameshift from frame 2 into frame 1 in the previously
                     sequenced DNA. Contains Pfam match to entry PF00528
                     BPD_transp, Binding-protein-dependent transport systems
                     inner membrane component and match to Prosite entry PS00402
                     Binding-protein-dependent transport systems inner membrane
                     comp sign. Also contains possible hydrophobic membrane
                     spanning regions"
                     /product="ABC transporter integral membrane protein BldKA"
                     /protein_id="NP_629262.1"
                     /transl_table=11
                     /translation="MTSPIEIEGAEASSVLDKESAPQGDAPKPKEPEGRKPGQLMWARF
                     KRDRAGVISAFVVLFFFVIAAAAPLISMVYGKDPYTLYGQDNPDLLDMFTMPAAPYGGI
                     DGDFWFGIEPGLGRDVFTQLLYGMRNSMATALAATIIMTVLGVLIGLAGGYFGGKIDYW
                     LGRITDFFMALPSQLFFVAAMPVITTVFVAPDKETPTYVRAAAIIIVLSFLGWMSMARI
                     VRGATMSLRDREFIEAARISGASPWRILRKELLPNIVTPTLVQATLTLPSTILSIAFLS
                     FVGVGYVEPTPDWGRMFAIGADIVEQDPYYMLFPGVAMVIFIVAFNLLGDSVRDAFDPK
                     GNR"
     PFAM_domain     62663..62809
                     /aSDomain="OppC_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF12911.10"
                     /description="N-terminal TM domain of oligopeptide
                     transport permease C"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5112_0474"
                     /evalue="2.60E-09"
                     /label="SCO5112"
                     /locus_tag="SCO5112"
                     /protein_end="85"
                     /protein_start="36"
                     /score="37.0"
                     /tool="antismash"
                     /translation="PGQLMWARFKRDRAGVISAFVVLFFFVIAAAAPLISMVYGKDPYT
                     LYGQ"
     PFAM_domain     62990..63574
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00528.25"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5112_0475"
                     /evalue="1.40E-30"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO5112"
                     /locus_tag="SCO5112"
                     /protein_end="340"
                     /protein_start="145"
                     /score="106.5"
                     /tool="antismash"
                     /translation="GVLIGLAGGYFGGKIDYWLGRITDFFMALPSQLFFVAAMPVITTV
                     FVAPDKETPTYVRAAAIIIVLSFLGWMSMARIVRGATMSLRDREFIEAARISGASPWRI
                     LRKELLPNIVTPTLVQATLTLPSTILSIAFLSFVGVGYVEPTPDWGRMFAIGADIVEQD
                     PYYMLFPGVAMVIFIVAFNLLGDSVRDAFDPK"
     misc_feature    63233..63463
                     /gene_synonym="bldKA; SCBAC31E11.08"
                     /locus_tag="SCO5112"
                     /note="Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 51.00, E-value 2.6e-11"
     misc_feature    63236..63322
                     /gene_synonym="bldKA; SCBAC31E11.08"
                     /locus_tag="SCO5112"
                     /note="PS00402 Binding-protein-dependent transport systems
                     inner membrane comp sign."
     gene            63698..65500
                     /db_xref="GeneID:1100554"
                     /gene_synonym="bldKB; SCBAC31E11.09"
                     /locus_tag="SCO5113"
     CDS             63698..65500
                     /codon_start=1
                     /db_xref="GeneID:1100554"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /gene_synonym="bldKB; SCBAC31E11.09"
                     /locus_tag="SCO5113"
                     /note="SCBAC31E11.09, bldKB, possible ABC transport system
                     lipoprotein, len: 600 aa; almost identical to TR:P72407
                     (EMBL:U68036) Streptomyces coelicolor BldKB, 602 aa.
                     Contains 4x Pfam matches to entry PF00496 SBP_bac_5,
                     Bacterial extracellular solute-binding proteins, family 5,
                     match to Prosite entry PS00017 ATP/GTP-binding site motif A
                     (P-loop) and correctly situated match to Prosite entry
                     PS00013 Prokaryotic membrane lipoprotein lipid attachment
                     site. Also contains possible N-terminal region signal
                     peptide sequence"
                     /product="ABC transporter lipoprotein BldKB"
                     /protein_id="NP_629263.1"
                     /transl_table=11
                     /translation="MSILRNRTATAAIVAVAAGALTLTACGGGDSDSSAKDNSKKKEDA
                     KSQSKPVQIGDAQASTGPAPEVPGAKPGGTMTVYQTADFSHLDPGQIYVSDGKLLGRLI
                     FRGLTQYDEDENGNLTVVGDLATDAGKQTDGGKTWTYTLKDNLKDANGNPINSADIRHT
                     IERMYSSYITDGPTYLQQWLSGDGTTYRDAYAGPDKGKHLPDNVLETPDDKTIVFHFKT
                     ARPDLPQMLTMPGYSVVPEETDTKEKYDSAPVAAGPYKIAEFKPGKSMKLVKNTQWDPK
                     SDSVRHQYVDGFNIEMNHDDEDQTKTLLADQGGAKNAMMFTGQVATTQLQKVVGDKDAM
                     KNRTIQGYAPYVWQLNFNMNRVKDKKLRDAITLALPSDSVFKADGGAYGGEVANSLMSP
                     TTPGYDEAFDPFGRAKKPNGDIEAAKKLIKEGGFEGKSLVYAYANTPERQKQAVLISTA
                     LEKIGLDIQKKEIDSATWYEQVGKVDNGLDLYMTGWGQDWPSASTVIPPVYDGKQIQDG
                     ASNYSHINDDHVNSEIQRIQQITDTAEATKAWAELNEYISKEVNPAAPIYYTKVFQIFG
                     SNVGGIRYSSDSSYVDVTRVFLKK"
     misc_feature    63743..63775
                     /gene_synonym="bldKB; SCBAC31E11.09"
                     /locus_tag="SCO5113"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site"
     misc_feature    63746..63835
                     /gene_synonym="bldKB; SCBAC31E11.09"
                     /locus_tag="SCO5113"
                     /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial
                     extracellular solute-binding proteins, family 5, score
                     1.40, E-value 13"
     PFAM_domain     64055..65239
                     /aSDomain="SBP_bac_5"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00496.25"
                     /description="Bacterial extracellular solute-binding
                     proteins, family 5 Middle"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5113_0476"
                     /evalue="5.60E-63"
                     /label="SCO5113"
                     /locus_tag="SCO5113"
                     /protein_end="514"
                     /protein_start="119"
                     /score="213.3"
                     /tool="antismash"
                     /translation="TVVGDLATDAGKQTDGGKTWTYTLKDNLKDANGNPINSADIRHTI
                     ERMYSSYITDGPTYLQQWLSGDGTTYRDAYAGPDKGKHLPDNVLETPDDKTIVFHFKTA
                     RPDLPQMLTMPGYSVVPEETDTKEKYDSAPVAAGPYKIAEFKPGKSMKLVKNTQWDPKS
                     DSVRHQYVDGFNIEMNHDDEDQTKTLLADQGGAKNAMMFTGQVATTQLQKVVGDKDAMK
                     NRTIQGYAPYVWQLNFNMNRVKDKKLRDAITLALPSDSVFKADGGAYGGEVANSLMSPT
                     TPGYDEAFDPFGRAKKPNGDIEAAKKLIKEGGFEGKSLVYAYANTPERQKQAVLISTAL
                     EKIGLDIQKKEIDSATWYEQVGKVDNGLDLYMTGWGQDWPSASTVIPPVYDGKQI"
     misc_feature    64097..64165
                     /gene_synonym="bldKB; SCBAC31E11.09"
                     /locus_tag="SCO5113"
                     /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial
                     extracellular solute-binding proteins, family 5, score
                     5.20, E-value 1.2"
     misc_feature    64331..64522
                     /gene_synonym="bldKB; SCBAC31E11.09"
                     /locus_tag="SCO5113"
                     /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial
                     extracellular solute-binding proteins, family 5, score
                     19.80, E-value 9.6e-05"
     misc_feature    64481..64504
                     /gene_synonym="bldKB; SCBAC31E11.09"
                     /locus_tag="SCO5113"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     misc_feature    64784..65491
                     /gene_synonym="bldKB; SCBAC31E11.09"
                     /locus_tag="SCO5113"
                     /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial
                     extracellular solute-binding proteins, family 5, score
                     8.50, E-value 0.13"
     PFAM_domain     65614..65952
                     /aSDomain="BPD_transp_1_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19300.2"
                     /description="Binding-prot-dependent transport system
                     membrane comp, N-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5114_0477"
                     /evalue="8.40E-56"
                     /label="SCO5114"
                     /locus_tag="SCO5114"
                     /protein_end="113"
                     /protein_start="0"
                     /score="187.2"
                     /tool="antismash"
                     /translation="MLQFLIRRSFGAVLILVLISAFTFFMFFAIPQDPAMLACGKNCTP
                     DALEIIHKNLGLDQPVTVQYWHFLAGIFTGRDFAVGHCDAPCFGVSFANNQNVWDTILD
                     RFPLTVSLT"
     gene            65614..66591
                     /db_xref="GeneID:1100555"
                     /gene_synonym="bldKC; SCBAC31E11.10"
                     /locus_tag="SCO5114"
     CDS             65614..66591
                     /codon_start=1
                     /db_xref="GeneID:1100555"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /gene_synonym="bldKC; SCBAC31E11.10"
                     /locus_tag="SCO5114"
                     /note="SCBAC31E11.10, bldKC, possible ABC transport system
                     integral membrane protein, len: 325 aa; almost identical to
                     previously sequenced TR:P72408 (EMBL:U68036) Streptomyces
                     coelicolor BldKC, 323 aa. Contains Pfam match to entry
                     PF00528 BPD_transp, Binding-protein-dependent transport
                     systems inner membrane component. Also contains possible
                     hydrophobic membrane spanning regions"
                     /product="ABC transporter integral membrane protein BldKC"
                     /protein_id="NP_629264.1"
                     /transl_table=11
                     /translation="MLQFLIRRSFGAVLILVLISAFTFFMFFAIPQDPAMLACGKNCTP
                     DALEIIHKNLGLDQPVTVQYWHFLAGIFTGRDFAVGHCDAPCFGVSFANNQNVWDTILD
                     RFPLTVSLTVGSLIVFLIVGLGAGLLAAKNRGTWIDKVFSSGSLVVSSLQIYFLGPLVL
                     LALVYSTGWLQKPKYVPISEDAAGWFAGLLIPWIVMATIFTANYTRMSRSSMIEQLQEE
                     HVRAARAKGMSSNYTFFRYAWRGSLVPIVTILGIDLSALMGGGMVTEMTFGLAGIGRLA
                     LESVINKDLPMLMGVMLVSAALIIVFNLIVDAMYAVIDPRVRLS"
     PFAM_domain     65983..66582
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00528.25"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5114_0478"
                     /evalue="3.40E-35"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO5114"
                     /locus_tag="SCO5114"
                     /protein_end="323"
                     /protein_start="123"
                     /score="121.6"
                     /tool="antismash"
                     /translation="GLGAGLLAAKNRGTWIDKVFSSGSLVVSSLQIYFLGPLVLLALVY
                     STGWLQKPKYVPISEDAAGWFAGLLIPWIVMATIFTANYTRMSRSSMIEQLQEEHVRAA
                     RAKGMSSNYTFFRYAWRGSLVPIVTILGIDLSALMGGGMVTEMTFGLAGIGRLALESVI
                     NKDLPMLMGVMLVSAALIIVFNLIVDAMYAVIDPRVR"
     misc_feature    66256..66471
                     /gene_synonym="bldKC; SCBAC31E11.10"
                     /locus_tag="SCO5114"
                     /note="Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 25.30, E-value 0.0015"
     regulatory      66590..66594
                     /regulatory_class="ribosome_binding_site"
     gene            66602..67663
                     /db_xref="GeneID:1100556"
                     /gene_synonym="bldKD; SCBAC31E11.11"
                     /locus_tag="SCO5115"
     CDS             66602..67663
                     /codon_start=1
                     /db_xref="GeneID:1100556"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /gene_synonym="bldKD; SCBAC31E11.11"
                     /locus_tag="SCO5115"
                     /note="SCBAC31E11.11, bldKD, ABC transporter intracellular
                     ATPase subunit, len: 353 aa; almost identical to previously
                     sequenced TR:P72409 (EMBL:U680360) Streptomyces coelicolor
                     BldKD ABC transporter intracellular ATPase subunit, 353 aa
                     and similar to TR:O86574 (EMBL:AL031184) Streptomyces
                     coelicolor SC2A11.13, 366 aa; fasta scores: opt: 1427
                     Z-score: 1344.1 bits: 257.3 E(): 3.8e-69; 60.340% identity
                     in 353 aa overlap. Contains Pfam match to entry PF00005
                     ABC_tran, ABC transporter and match to Prosite entry
                     PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211
                     ABC transporters family signature"
                     /product="ABC transporter intracellular ATPase subunit
                     BldKD"
                     /protein_id="NP_629265.1"
                     /transl_table=11
                     /translation="MTTQTKPEEAPAAAAGDAFLSVRDLKVHFSTEGGVVKAVDGLSFD
                     LERGKTLGIVGESGSGKSVTNLAVLGLHDRRRTAIDGSITLDGQELTDASEKQLEKLRG
                     KKMAMIFQDALTALSPYYTVGRQIAEPFMKHNGASKKDARVRAIDLLQKVGIPHPQKRV
                     DDYPHQFSGGMRQRAMIAMALSCNPDLLIADEPTTALDVTVQAQILDLLKDLQQEFGSA
                     IIMITHDLGVVGNMADDIMVMYAGRAVERGTVREVLKSPQHPYTWGLLSSMPNLTSDVD
                     EPLMPIPGSPPSLMNPPSGCAFHPRCGFTDLVSGERCSGERPTLPHGRAAACHLTGDQR
                     QQVFIEKIQPRLG"
     PFAM_domain     66719..67192
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00005.30"
                     /db_xref="GO:0005524"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5115_0479"
                     /evalue="4.80E-29"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /label="SCO5115"
                     /locus_tag="SCO5115"
                     /protein_end="197"
                     /protein_start="39"
                     /score="101.7"
                     /tool="antismash"
                     /translation="DGLSFDLERGKTLGIVGESGSGKSVTNLAVLGLHDRRRTAIDGSI
                     TLDGQELTDASEKQLEKLRGKKMAMIFQDALTALSPYYTVGRQIAEPFMKHNGASKKDA
                     RVRAIDLLQKVGIPHPQKRVDDYPHQFSGGMRQRAMIAMALSCNPDLLIADEPT"
     misc_feature    66746..67339
                     /gene_synonym="bldKD; SCBAC31E11.11"
                     /locus_tag="SCO5115"
                     /note="Pfam match to entry PF00005 ABC_tran, ABC
                     transporter, score 208.90, E-value 7.7e-59"
     misc_feature    66767..66790
                     /gene_synonym="bldKD; SCBAC31E11.11"
                     /locus_tag="SCO5115"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     misc_feature    67109..67153
                     /gene_synonym="bldKD; SCBAC31E11.11"
                     /locus_tag="SCO5115"
                     /note="PS00211 ABC transporters family signature"
     aSDomain        67343..67603
                     /aSDomain="TIGR01727"
                     /aSTool="tigrfam"
                     /description="oligo_HPY: oligopeptide/dipeptide ABC
                     transporter, ATP-binding protein, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5115_0056"
                     /evalue="1.00E-21"
                     /identifier="TIGR01727"
                     /label="SCO5115"
                     /locus_tag="SCO5115"
                     /protein_end="334"
                     /protein_start="247"
                     /score="74.8"
                     /tool="antismash"
                     /translation="AVERGTVREVLKSPQHPYTWGLLSSMPNLTSDVDEPLMPIPGSPP
                     SLMNPPSGCAFHPRCGFTDLVSGERCSGERPTLPHGRAAACH"
     PFAM_domain     67346..67528
                     /aSDomain="oligo_HPY"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08352.15"
                     /db_xref="GO:0000166"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0015833"
                     /description="Oligopeptide/dipeptide transporter,
                     C-terminal region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5115_0480"
                     /evalue="2.00E-16"
                     /gene_ontologies="GO:0000166: nucleotide binding"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0015833: peptide transport"
                     /label="SCO5115"
                     /locus_tag="SCO5115"
                     /protein_end="309"
                     /protein_start="248"
                     /score="60.4"
                     /tool="antismash"
                     /translation="VERGTVREVLKSPQHPYTWGLLSSMPNLTSDVDEPLMPIPGSPPS
                     LMNPPSGCAFHPRCGF"
     gene            67691..68836
                     /db_xref="GeneID:1100557"
                     /gene_synonym="bldKE; SC9E12.01; SCBAC31E11.12"
                     /locus_tag="SCO5116"
     CDS             67691..68836
                     /codon_start=1
                     /db_xref="GeneID:1100557"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /gene_synonym="bldKE; SC9E12.01; SCBAC31E11.12"
                     /locus_tag="SCO5116"
                     /note="SC9E12.01, probable peptide transport system
                     ATP-binding protein (fragment), len: >142 aa; similar to
                     SW:OPPF_ECOLI (EMBL:AE000223) Escherichia coli oligopeptide
                     transport protein ATP-binding protein OppF, 334 aa; fasta
                     scores: opt: 344 z-score: 423.0 E(): 4.3e-16; 56.5%
                     identity in 92 aa overlap and to TR:O86575 (EMBL:AL031184)
                     Streptomyces coelicolor oligopeptide ABC transporter
                     ATP-binding protein SC2A11.14, 496 aa; fasta scores: opt:
                     488 z-score: 576.6 E(): 1.7e-26; 56.6% identity in 136 aa
                     overlap; SCBAC31E11.12, bldKE, ABC transporter
                     intracellular ATPase subunit (fragment), len: >272 aa;
                     almost identical to previously sequenced TR:P72410
                     (EMBL:U68036) Streptomyces coelicolor ABC transporter
                     intracellular ATPase subunit (fragment) BldKE, 284 aa and
                     similar to N-terminal region of TR:O86575 (EMBL:AL031184)
                     Streptomyces coelicolor SC2A11.14, 497 aa; fasta scores:
                     opt: 1186 Z-score: 1170.6 bits: 225.2 E(): 1.7e-59; 63.603%
                     identity in 272 aa overlap. Contains Pfam match to entry
                     PF00005 ABC_tran, ABC transporter and matches to Prosite
                     entries PS00017 ATP/GTP-binding site motif A (P-loop) and
                     PS00211 ABC transporters family signature"
                     /product="peptide transport system ATP-binding subunit"
                     /protein_id="NP_733655.1"
                     /transl_table=11
                     /translation="MSDNSKTTTAVADDFPQQRDGDTAPLLKVSGLSKHFPIKGGFPIK
                     RTVGHVKAVDGVDFEVFPGESLGLVGESGCGKSTTGRLLTRLYEPTQGSIEYRGKDITR
                     ANRRELAPVRSEIQMIFQDPYASLNPRQTVGTIISGPMEINGINPPGGREKRVRELLEI
                     VGLNPEHYNRFPHEFSGGQRQRIGVARAVALQPKLIVADEPVSALDVSIQAQVVNLLQE
                     VQREMGIAFVFIAHDLAIVRHFSQRVAVMYLGKIVEIADRDSLYNRPRHPYTHALLSAV
                     PETDLDAEKRERIRLEGDVPSPISPPSGCRFRTRCWKAQDKCATEEPPLVQLSGNREGH
                     LTACHFPEEGSTEARAEDIVMDPGLKAMEDGADGGATLSKG"
     misc_feature    complement(67722..67736)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
     PFAM_domain     67853..68305
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00005.30"
                     /db_xref="GO:0005524"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5116_0481"
                     /evalue="9.00E-31"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /label="SCO5116"
                     /locus_tag="SCO5116"
                     /protein_end="205"
                     /protein_start="54"
                     /score="107.3"
                     /tool="antismash"
                     /translation="DGVDFEVFPGESLGLVGESGCGKSTTGRLLTRLYEPTQGSIEYRG
                     KDITRANRRELAPVRSEIQMIFQDPYASLNPRQTVGTIISGPMEINGINPPGGREKRVR
                     ELLEIVGLNPEHYNRFPHEFSGGQRQRIGVARAVALQPKLIVADEPV"
     misc_feature    67880..68452
                     /gene_synonym="bldKE; SC9E12.01; SCBAC31E11.12"
                     /locus_tag="SCO5116"
                     /note="Pfam match to entry PF00005 ABC_tran, ABC
                     transporter, score 192.00, E-value 9.3e-54"
     misc_feature    67901..67924
                     /gene_synonym="bldKE; SC9E12.01; SCBAC31E11.12"
                     /locus_tag="SCO5116"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     misc_feature    68222..68266
                     /gene_synonym="bldKE; SC9E12.01; SCBAC31E11.12"
                     /locus_tag="SCO5116"
                     /note="PS00211 ABC transporters family signature"
     aSDomain        68453..68728
                     /aSDomain="TIGR01727"
                     /aSTool="tigrfam"
                     /description="oligo_HPY: oligopeptide/dipeptide ABC
                     transporter, ATP-binding protein, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO5116_0057"
                     /evalue="5.40E-28"
                     /identifier="TIGR01727"
                     /label="SCO5116"
                     /locus_tag="SCO5116"
                     /protein_end="346"
                     /protein_start="254"
                     /score="94.9"
                     /tool="antismash"
                     /translation="KIVEIADRDSLYNRPRHPYTHALLSAVPETDLDAEKRERIRLEGD
                     VPSPISPPSGCRFRTRCWKAQDKCATEEPPLVQLSGNREGHLTACHF"
     PFAM_domain     68459..68659
                     /aSDomain="oligo_HPY"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08352.15"
                     /db_xref="GO:0000166"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0015833"
                     /description="Oligopeptide/dipeptide transporter,
                     C-terminal region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5116_0482"
                     /evalue="3.60E-17"
                     /gene_ontologies="GO:0000166: nucleotide binding"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0015833: peptide transport"
                     /label="SCO5116"
                     /locus_tag="SCO5116"
                     /protein_end="323"
                     /protein_start="256"
                     /score="62.7"
                     /tool="antismash"
                     /translation="VEIADRDSLYNRPRHPYTHALLSAVPETDLDAEKRERIRLEGDVP
                     SPISPPSGCRFRTRCWKAQDKC"
     stem_loop       68853..68895
                     /note="possible stem loop. Score 57: 19/19 (100%) matches,
                     0 gaps"
     regulatory      69024..69029
                     /regulatory_class="ribosome_binding_site"
     gene            69036..70670
                     /db_xref="GeneID:1100558"
                     /gene_synonym="SC9E12.02"
                     /locus_tag="SCO5117"
     CDS             69036..70670
                     /codon_start=1
                     /db_xref="GeneID:1100558"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /gene_synonym="SC9E12.02"
                     /locus_tag="SCO5117"
                     /note="SC9E12.02, possible peptide transport system
                     peptide-binding protein, len: 544 aa; similar to
                     SW:OPPA_BACSU (EMBL:X56347) Bacillus subtilis
                     oligopeptide-binding protein OppA precursor, 545 aa; fasta
                     scores: opt: 648 z-score: 642.6 E(): 2.5e-28; 26.1%
                     identity in 552 aa overlap and to TR:P72407 (EMBL:U68036)
                     Streptomyces coelicolor SpoOKA homologue BldKB, 602 aa;
                     blastp scores: Score = 165 (58.1 bits), Expect = 2.9e-10,
                     Sum P(2) = 2.9e-10; Identities = 116/502 (23%), Positives =
                     202/502 (40%). Contains 2x Pfam matches to entry PF00496
                     SBP_bac_5, Bacterial extracellular solute-binding proteins,
                     family 5 and correctly situated match to Prosite entry
                     PS00013 Prokaryotic membrane lipoprotein lipid attachment
                     site. Also contains possible N-terminal region signal
                     peptide sequence"
                     /product="peptide transport system peptide-binding protein"
                     /protein_id="NP_629266.1"
                     /transl_table=11
                     /translation="MRGATHARWAACAAAVALAATACGGGGGDGGSGGGSGGVLSSSWG
                     DPQNPLEPANTNEVQGGKVLDMIFRGLKKYDPGTGEAQNMLAEKIDTSDSQNFTVTVKD
                     GWTFSNGEKVTAQSFVDAWNYGASLKNNQRNAYFFAYIDGYDKVHPESGSQSTDTLSGL
                     KVTGPRTFTIKLSQKFSTFPDTLGYPAFAPLPKAFFDDHDAWLKKPVGNGPYQVDNYTR
                     GSQMSLRKWDDYPGPDKAQNGGVDLKVYTDNNTAYTDLIAGNLDLVDDVPASQLKNVKN
                     DLGDRYINTPAGIIQTLAFPFYDNDWNKSGSEKVRKGLSMAIDRKQITDTIFQNTRTPA
                     TDWTSPVLGKDGGYKPGLCGDACEYNAAEAKKLVKEGGGLPGGQVKITYNADTGSHKQW
                     VDAVCNSINNALDNDRACAGNPVGTFADFRNQITNQKMSGPFRAGWQMDYPLIQNFLQP
                     LYYTNASSNDGKWSSKKFDDLVDQANAETDTAKAVGLFQQAEEVLRDDMGAIPLWYQNG
                     SAGYSDRLSNVKLNPFSVPVYNEIKVG"
     misc_feature    69072..69104
                     /gene_synonym="SC9E12.02"
                     /locus_tag="SCO5117"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site"
     misc_feature    69186..70169
                     /gene_synonym="SC9E12.02"
                     /locus_tag="SCO5117"
                     /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial
                     extracellular solute-binding proteins, family 5, score
                     85.80, E-value 3.8e-23"
     PFAM_domain     69282..70424
                     /aSDomain="SBP_bac_5"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00496.25"
                     /description="Bacterial extracellular solute-binding
                     proteins, family 5 Middle"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5117_0483"
                     /evalue="6.00E-48"
                     /label="SCO5117"
                     /locus_tag="SCO5117"
                     /protein_end="463"
                     /protein_start="82"
                     /score="163.9"
                     /tool="antismash"
                     /translation="QNMLAEKIDTSDSQNFTVTVKDGWTFSNGEKVTAQSFVDAWNYGA
                     SLKNNQRNAYFFAYIDGYDKVHPESGSQSTDTLSGLKVTGPRTFTIKLSQKFSTFPDTL
                     GYPAFAPLPKAFFDDHDAWLKKPVGNGPYQVDNYTRGSQMSLRKWDDYPGPDKAQNGGV
                     DLKVYTDNNTAYTDLIAGNLDLVDDVPASQLKNVKNDLGDRYINTPAGIIQTLAFPFYD
                     NDWNKSGSEKVRKGLSMAIDRKQITDTIFQNTRTPATDWTSPVLGKDGGYKPGLCGDAC
                     EYNAAEAKKLVKEGGGLPGGQVKITYNADTGSHKQWVDAVCNSINNALDNDRACAGNPV
                     GTFADFRNQITNQKMSGPFRAGWQMDYPLIQNFLQPLYYTN"
     misc_feature    70359..70664
                     /gene_synonym="SC9E12.02"
                     /locus_tag="SCO5117"
                     /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial
                     extracellular solute-binding proteins, family 5, score
                     38.20, E-value 7.2e-10"
     regulatory      70669..70672
                     /regulatory_class="ribosome_binding_site"
     PFAM_domain     70680..70910
                     /aSDomain="BPD_transp_1_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19300.2"
                     /description="Binding-prot-dependent transport system
                     membrane comp, N-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5118_0484"
                     /evalue="8.90E-12"
                     /label="SCO5118"
                     /locus_tag="SCO5118"
                     /protein_end="77"
                     /protein_start="0"
                     /score="45.3"
                     /tool="antismash"
                     /translation="MGRYVVRRLLQMIPVFIGATLLIFLMVNVMGDPIAGLCGDRECDP
                     ATAAQLRHEFGLDQPVWQQYATYMGNVFTGDF"
     gene            70680..71603
                     /db_xref="GeneID:1100559"
                     /gene_synonym="SC9E12.03"
                     /locus_tag="SCO5118"
     CDS             70680..71603
                     /codon_start=1
                     /db_xref="GeneID:1100559"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /gene_synonym="SC9E12.03"
                     /locus_tag="SCO5118"
                     /note="SC9E12.03, probable peptide transport system
                     integral membrane protein, len: 307 aa; similar to TR:
                     SW:OPPB_BACSU (EMBL:X56347) Bacillus subtilis oligopeptide
                     transport system permease OppB, 311 aa; fasta scores: opt:
                     688 z-score: 788.7 E(): 0; 36.0% identity in 308 aa overlap
                     and to TR:P72408 (EMBL:U68036) Streptomyces coelicolor
                     SpoOKC homologue BldKC, 323 aa; blastp scores: Score = 354
                     (124.6 bits), Expect = 1.9e-32, P = 1.9e-32; Identities =
                     82/235 (34%), Positives = 138/235 (58%). Contains Pfam
                     match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component. Also contains possible hydrophobic membrane
                     spanning regions"
                     /product="peptide transport system integral membrane
                     protein"
                     /protein_id="NP_629267.1"
                     /transl_table=11
                     /translation="MGRYVVRRLLQMIPVFIGATLLIFLMVNVMGDPIAGLCGDRECDP
                     ATAAQLRHEFGLDQPVWQQYATYMGNVFTGDFGTAFNGQPVTELMGTAFPVTIRLTIVA
                     ILFEIVVGIILGVLTGLRRGRPVDTGVLLLTLVVISVPTFVTGLLLQLLLGVKWGWIDP
                     AVSSEAAFGELIVPGLVLASVSLAYVTRLTRTSIAENRRSDYVRTAIAKGLPRHRVITR
                     HLLRNSLIPVVTFIGTDIGALMGGAIVTERIFNIHGVGYQLYQGILRQNTQTVVGFVTV
                     LVLVFLVANLVVDLLYAVLDPRIRYA"
     PFAM_domain     71013..71597
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00528.25"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5118_0485"
                     /evalue="8.90E-39"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO5118"
                     /locus_tag="SCO5118"
                     /protein_end="306"
                     /protein_start="111"
                     /score="133.3"
                     /tool="antismash"
                     /translation="GIILGVLTGLRRGRPVDTGVLLLTLVVISVPTFVTGLLLQLLLGV
                     KWGWIDPAVSSEAAFGELIVPGLVLASVSLAYVTRLTRTSIAENRRSDYVRTAIAKGLP
                     RHRVITRHLLRNSLIPVVTFIGTDIGALMGGAIVTERIFNIHGVGYQLYQGILRQNTQT
                     VVGFVTVLVLVFLVANLVVDLLYAVLDPRIRY"
     misc_feature    71268..71483
                     /gene_synonym="SC9E12.03"
                     /locus_tag="SCO5118"
                     /note="Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 24.20, E-value 0.0031"
     gene            71659..72576
                     /db_xref="GeneID:1100560"
                     /gene_synonym="SC9E12.04"
                     /locus_tag="SCO5119"
     CDS             71659..72576
                     /codon_start=1
                     /db_xref="GeneID:1100560"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /gene_synonym="SC9E12.04"
                     /locus_tag="SCO5119"
                     /note="SC9E12.04, probable peptide transport system
                     integral membrane protein, len: 305 aa; similar to
                     SW:OPPC_BACSU (EMBL:X56347) Bacillus subtilis oligopeptide
                     transport system permease OppC, 305 aa; fasta scores: opt:
                     670 z-score: 745.0 E(): 0; 35.5% identity in 296 aa overlap
                     and to TR:P72406 (EMBL:U68036) Streptomyces coelicolor
                     SpoOKB homologue BldKA, 335 aa; blastp scores: Score = 382
                     (134.5 bits), Expect = 9.1e-41, Sum P(2) = 9.1e-41;
                     Identities = 88/231 (38%), Positives = 134/231 (58%).
                     Contains Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component and possible hydrophobic membrane spanning
                     regions"
                     /product="peptide transport system integral membrane
                     protein"
                     /protein_id="NP_629268.1"
                     /transl_table=11
                     /translation="MDLGASEAVTLEQPPGPDGADPRDKPRSLWTDAWHDLRRNPVFII
                     SALVIIFLIVISIWPSLIASGSPLKCDLAKAQEGSQPGHPFGFNGQGCDVYTRTVYGAR
                     TSVAVGILATLGVALLGSVLGGLAGFFGGGGDAVLSRITDIFFAIPVVLGGLVLLSVIT
                     SNTIWPVIGFIVLLGWPQISRIARGSVITAKQNDYVQAARALGASNSRLLLRHIAPNAV
                     APVIVVATIALGTYISLEATLSFLGVGLKPPSVSWGIDISSAAPYVRNAPHALLWPSGA
                     LAITVLAFIMLGDAVRDALDPKLR"
     PFAM_domain     71740..71853
                     /aSDomain="OppC_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF12911.10"
                     /description="N-terminal TM domain of oligopeptide
                     transport permease C"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5119_0486"
                     /evalue="2.40E-09"
                     /label="SCO5119"
                     /locus_tag="SCO5119"
                     /protein_end="65"
                     /protein_start="27"
                     /score="37.1"
                     /tool="antismash"
                     /translation="SLWTDAWHDLRRNPVFIISALVIIFLIVISIWPSLIAS"
     PFAM_domain     72019..72573
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00528.25"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO5119_0487"
                     /evalue="2.70E-26"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO5119"
                     /locus_tag="SCO5119"
                     /protein_end="305"
                     /protein_start="120"
                     /score="92.6"
                     /tool="antismash"
                     /translation="GSVLGGLAGFFGGGGDAVLSRITDIFFAIPVVLGGLVLLSVITSN
                     TIWPVIGFIVLLGWPQISRIARGSVITAKQNDYVQAARALGASNSRLLLRHIAPNAVAP
                     VIVVATIALGTYISLEATLSFLGVGLKPPSVSWGIDISSAAPYVRNAPHALLWPSGALA
                     ITVLAFIMLGDAVRDALDPKLR"
     misc_feature    72226..72456
                     /gene_synonym="SC9E12.04"
                     /locus_tag="SCO5119"
                     /note="Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 21.60, E-value 0.018"
ORIGIN
        1 accgcgtacc cgcgcttgag ggtggcggcg ggggagaggg ccaccacgcg cgcgtgcgtg
       61 tgcgtcagct cggagtcggc ccggtcgagg tggtgccgca gcgaacggcg tccccggtcc
      121 aggagcgccg tcacctgctc ggcccgctcc tcgatcatcc ggtgcggatc ctgtatcgac
      181 ggccgggcca gcgcgtgggc cagcccgcgc tcctcgcggt cgacgaacgc cgccacacac
      241 cgccgggcgc ggtcccgcag cagccgtacc cgctcgtact cctcgccgac gtccggcacg
      301 accttcttcg cggcgtcggt cggcgtggag gcgcgcaggt cggccaccag gtcgagcagc
      361 gggctgtccg gctcgtggcc gatcgccgag acgaccggcg tgcgacaggc ggcgaccgcc
      421 cgcaccagct gctcgtcgga gaacggcagc aggtcctcca cgctgccgcc gccccgcgcg
      481 acgacgatca cgtccacgtc atcccgcgcg tccagctcct tcaccgcctg caccacctgc
      541 ggcaccgcgt gcacgccctg caccgggacg ttgcgcacct cgaagcggac ggcgggccag
      601 cggtgccggg cgttctccag gacgtcccgc tcggcggccg aggcccgccc gcacaccaga
      661 ccgatcagct gcggcaggaa cggcagcggc tgcttccgct ccgccgcgaa cagcccctcg
      721 cgcgcgagcg ccttcttcag ctgctccagc cgcgccagca gctcaccgac gcccaccggc
      781 ttgatctcgg cggcccgcag cgacagctgc ccccgcggcg cgtaccactc cggcttcgcg
      841 tgcacgacca cccgcgcgcc ctcgccgacc acgtccgcca cggcgtcgaa cacctgccgg
      901 tagcaggtca cgctcacgga gatgtcgtac gacgggtcgc gcagcgtcag gaacaccaca
      961 ccggcgcccg gccgccgcga caactgggtg atctgcccct cgacccagac cgcgccgagc
     1021 cggtcgatcc agcccccgat cagccgggac acctcgccca cgggcagcgg accttcaggg
     1081 gtcgagttgg cagccatgcg cccgagcgta acggccgggt ccgacaatcc ggccccagcg
     1141 atcccgttcc ccgcacccac cgaccgcacc accaccccct gccgcgcccc ggcccccccg
     1201 ccccgccgtc cctccaccgc cacgcccgtc gtccccgggc ccgtggtctt gcagcgcgtg
     1261 ccgcgcgtgt gtcgcccccg tccgtggctc tcgcggccgt ggcccttcgg ctcgcgccgg
     1321 gcccgtgtcc ccacgcccgt cgtccccggt ccatggccct tcagcgcgtg ccgcgcgtgt
     1381 gttgcccccg tccgtggctc tcgcggccgt ggcccttcgg ctcgcgccgg gcccgtgtcc
     1441 ccacgcccgt cgtccccggt ccatggccct tcagcgcgcg ccgcgcgtgt gtcgccgtgg
     1501 ctgtgggtct tgcggcccat ggcctttcag ctcgcgccgg cctgtgtccc tgtgtccccg
     1561 cgtctgtcgg tccttcggag cccggccggc ccgtgagccg cgccgggccc gtgtccctgc
     1621 ggtccggcca cctgtcagtc gcgccgagcc gacgggcgcg cgcggcccac gcctcacgcc
     1681 cccgtcgtct ccgcgtcgcg ccgccccctc cactgcgccg ccagcaccac cagacccacc
     1741 gccagccaga tcgcgccgac cacctgggcc gtccccgacg cctccacgat caccgcgatc
     1801 gtgatcgccg cgccgagcac cggcaccagc agatgccgcc accagatcac ccggcccccg
     1861 ccgcgccgca ccacgaacca gcccaccacg ctcgcgtgca gcagcgtgaa cgcggtcagc
     1921 gcgcccacgt cgaccaccga gaccaggtgg tcgagaccgt cgtcccggcg tgccgcccac
     1981 accgccgccg ccatggtgat caccgccgac accagcagcg ccacgcgcgg caccccggcg
     2041 tccgtccgcg ccagcacccc cggcagccgc cggtcccggc ccatcgcgaa cagcagccgc
     2101 ccggccgccg cctgcccggc cagcgccgcg aacgccgcgc cgatcgcctt gctcaccgcc
     2161 accagatcgt gcagccacgt gcccaccgac acgtccacgg cgtcgtagaa cgccgacccc
     2221 tgccgctccg gctccgccgc cagctgcgcc gacgacaccg gctccagcag cgccaccagg
     2281 tacgtctgcg ccacgaacag cacgcccgcc agcgccagac agaacagcag cgcccgcgcg
     2341 accttcgccg aacctccggt gacctcctcg gcaaacgtgg cgatcgcgtc gaagcccagg
     2401 tacgacagca ccgccaccga caccgccccg accaccgccg acagcgcgaa cgccccctgg
     2461 gtgccgtccc ccgacagcgg cgacagccag tcgcgctcgg ccccgtcctg cgccaggacc
     2521 acgatcgccg tcgccacgaa gacgagcagt acgacgatct ccatggcgag caccaggaag
     2581 cccacccggg ccgccgtccg caccccccac aggttcagca gcgtcgtgac gaccaccgcg
     2641 atcgccgtcc acacccaccg cgacacctcg gggaccaggg cctccatcgc gatcccggag
     2701 aacaggtacg ccaccgcggg gatgaggatg tagtccagca tcgccatcca cccggcgacg
     2761 aacccggccc cgttgccgag ccccgcgcgc gcgtaggcga acaccgagcc cgcctggggg
     2821 accacccgca ccatctgcgc gtagctgaat gcggtgaacg ccatcgcgac cgtggcgacg
     2881 aggtagacga gggcgaccgc accgtgcgac ttggcgtcca gcgtgccgaa cacgccgacc
     2941 ggcgccatgg gcgcgatgaa cagcagcccg tagacgacca ggtccctgaa gcccagactg
     3001 cgcctcagcc gctcttcccc accggcctcc ggggccgtcg taccgctctg cgccatggtg
     3061 cctccgccag tgcctcggtc ctcgccccgg tttccgcttc gggctccgcc tcggaacgtt
     3121 cccgccagtc tccccggcaa cgccgcaccg ccgcgatctc tgacccgccg aacgcggcct
     3181 tacgatgggt gccatgactg cttcgcctgg ccgccgtgtc ctgctcgccg ccccccgtgg
     3241 ctactgcgcg ggtgtggacc gcgccgtgat cgccgtcgag aaagccctgg agcagtacgg
     3301 ggctccggtg tacgtccggc acgagatcgt ccacaacaag tacgtcgtcc agaccctgga
     3361 gaagaagggc gcgatcttcg tcgagcggac ggaggaggtc cccgagggga acatcgtgat
     3421 gttctccgcg cacggcgtgg cccccgtcgt ccacgaggag gccgagcgcg gcaagctcgc
     3481 caccatcgac gccacctgcc cgctcgtcac caaggtccac aaggaagccg tccgcttcgc
     3541 gaacgacgac tacgacatcc tgctcatcgg tcacgagggc cacgaggagg tcatcggcac
     3601 ctccggcgag gcccccgacc acatccagct cgtcgacggc cccgaggacg tcgcgaaggt
     3661 cgaggtccgc gacccgtcga aggtggtctg gctctcccag accaccctct ccgtcgacga
     3721 gacgatggag accgtcgacg cgctcaagga caagttcccg cagctcatct cgccgcccag
     3781 cgacgacatc tgctacgcca cgcagaaccg ccagctcgcg gtgaagcaga tgggtgccga
     3841 ggccgagctg gtgatcgtcg tcggctcccg caactcctcc aactccaagc gcctggtcga
     3901 ggtcgccaag caggccggct cccgcgcggc gtacctggtg gacttcgccg acgagatcga
     3961 cgagacctgg ctggacggcg tcaccacggt cggcgtcacc tccggcgcct ccgtcccgga
     4021 cgtgctggtc gagcaggtcc tggaatggct gtcgcggcgc ggcttcgagg acgtggagat
     4081 cgtcaaggcc gccgaggagt cgatcatctt ctcgctgccc aaggaactgc gccgcgacct
     4141 gcgcgaggag gcggcgtccc tggtggcgga gcggggcggc tccgggacgg cgggggcctg
     4201 accggccggg gcaccgcctg ggtgaccgtc agtggtccgt cgtaacgtag ggccatgcag
     4261 atcttcggcg tggacatcgg cggatccggg atcaagggcg cccctgtgga cctcgacagg
     4321 ggcgacctgg cccaggagcg ctgcaaggtg ctgaccccgc acccggccac ccccgacggc
     4381 gtggccgacg gggtcaagca ggtcgtcgag cacttcggct ggaccggacg ggtcggcctc
     4441 accttcccgg gcgttgtgac gggcggcgcg acggtgcgca ccgcggccaa cgtcgacaag
     4501 ggctgggtcg acaccgacgc gcgggcgctg ttcgccgagc ggctgggcgg gctcgacgtg
     4561 acggtcgtca acgacgcgga cgcggcgggc gtcgccgaga tgcacttcgg agccggccgc
     4621 ggccgcaagg gcacggtggt cctgctcacc ttcggcaccg gcatcggcag cgcggtgttc
     4681 accgacggcc tcctggtccc caacaccgag ctgggccacc tggagctgga cggtcacgac
     4741 gcggagaagc gcgcctccag caaggtcaag gacgaccacg acatgtcgtg ggagcactgg
     4801 gcccaccgcg tccagaagta cctcgcgcac gtcgagatgc tgttctcgcc ggagctcttc
     4861 atcatcggcg gcggggtcag ccgcaagtcc cagaagttcc tgccccacat caaggacgtc
     4921 cgggccgaga tcgtccccgc ccagctgcag aacaacgcgg ggatcgtggg cgcggcgatg
     4981 cacgcggccg gctgagcggg agcggtcacg cggggggccg gttgcgggcg gcggcggccc
     5041 ggcgccgcat cagccggatc cggcggacga tcacggtcga cccggcgacc agcgtcccgc
     5101 cgtacagcca cccggcctcg gtggccagcg cggtcacgat ccccatcagc cgtccgccga
     5161 gaccgccgtc cccgctctcc gccacgggca ccaggcccac ggcgaaggcg atcggcacga
     5221 cgacgggggc ggtcagcagg tcgccccggc gcacccagag cgcggtgagc agactcaccg
     5281 gcacgaacag caccccgtac gcggtgaggg acgagccgaa cagcagctcg tccaggaagc
     5341 ccagcagggt catcaccgcc gcgcagaaca ggccgctgcc cagccccgtc aaccgcggat
     5401 tgggcatccc gcgcagggca cgcaccaccc tcgccaccgg cgaaggggcc cccggagccg
     5461 gccgcaccgg ttccgggcgc cgtcccgcgg gcggcccgac ccgccccgca ggcggccgcg
     5521 cgacggcacc gccccgcccc tgtgcgggca gcggcgcccc gcttcgtcgc ggtccgtact
     5581 gggcaggtcg cgtcctgtgt tgctccactg gaccaactta ggtcggttta tgtgccgaat
     5641 aggccgacag acacgccgcc gggcgtgtct tggccaagcg ttcgactccg cgcgggtccg
     5701 gtacggcaca ccccgtagac tggtggatcg gcccatgcct ggcccgcccc atcccacccg
     5761 cccctccgca tctcacgtac gggaagtcgc aacgtgtcgc tcacgatcgg aatcgtcggt
     5821 ctgccgaatg tcggcaagtc gaccctgttc aacgccctga ccaagaacga cgtgctcgcg
     5881 gccaactacc cgttcgccac gatcgagccc aacgtcggcg tcgtgggcgt ccccgacccc
     5941 cgcctgacga agctggccga gatcttctcc tccgagaaga tcctcccggc cacggtcgac
     6001 ttcgtcgaca tcgcgggcat cgtgcgcggc gcgagcgagg gcgagggcct gggcaacaag
     6061 ttcctggcca acatccgcga gtccgacgcg atctgccagg tcatccgcgc cttcaaggac
     6121 gagaacgtcg tgcacgtcga cggcaaggtc tcgccgaagg acgacatcga gacgatcaac
     6181 accgagctga tcctcgccga cctccagacc atcgagaagg tccttccgcg cctccagaag
     6241 gagtcgcgca tcaagaagga cgtcgctccc aaggtcaagg cggtcgagga ggccaaggag
     6301 atcctggaga agggcgacac cctcttctcc cagggcatcc tccagggcag cgagcgcgcg
     6361 gagctcctcc acgacctcca cctcctcacc acgaagccct tcctctacgt cttcaacgtc
     6421 gacgaggacg agctgaccga cgacgacttc aagagcgagc agcgcgccct ggtcgccccc
     6481 gccgaggcga tcttcctcaa cgccaagctg gaggcggacc tcgccgagct ggacgaggac
     6541 gaggccctcg aactcctcca gtccgtcggc caggacgagc ccggcctcgc cactctcgcc
     6601 cacgtcggct tccgcaccct cggcctccag acctacctga cggccggccc caaggaatcc
     6661 cgcgcctgga ccatcaagaa gggcgccacc gcccccgagg ccgccggtgt catccacacc
     6721 gacttccaga agggcttcat caaggcggag gtcatctcct tcgacgacct ggtcgagacg
     6781 ggctcggtca ccgaggcccg cgcgaagggc aaggcccgca tggagggcaa ggagtacgtg
     6841 atgcgggacg gggatgtggt ggagttccgc ttcaacgtgt gacgtttcgt caagaaccgt
     6901 gcccgacccg cctgttgctg ggtcgggcac aagtctttgt ccgcggggag ccctcgccct
     6961 cgtcatgagg ggcagtgacg ggtctggtcg acgtgagacc gcctcagacc ttgacgaccc
     7021 ccacggaagg gccgcagagg agtgtcagat cctcggggtc ggacgtgagg acggtgaccg
     7081 gccgggacgc gtcgcgggcg atgacggcga aggcggcatc gatggcgtac gtgtggccgt
     7141 gcaggcgatg ggcgcgcagg agcgcggcgg cctggtcggt gatctccttg gtgacgtcgt
     7201 ggacgtcgac gcgggagagg atccacttga tgcgggccgg gtggatgcgc tcgtagtctg
     7261 cctcaagcgt ggtcatggcg ctggtggcca cgcgtacacc ctcttccgcc gccgcctgga
     7321 ccagggccat gacggtacgg tccttgcggt agagcttcga gagcccttcg ctgtcgagca
     7381 ggagggtgcc gggcatcagg cggcggcccc gccggcctgc cggtggtcgt ggcgcagcag
     7441 cgcccgggcg gcctcgacct cctcgtgggt gagagcttcg ttgtcggtct cgaagtcggc
     7501 gacgatctcc cgcagcttgt ccatggcgac ccgctgttcg agagcctcgg cgacataggc
     7561 ggagaaaccg ccgggcccga catgagcgcg tacggcctcg gcgagatcct cgggcaggct
     7621 gatcgaatac ttcctactac cgctcatggt gccgatccta ccggcggtcg taagcctggg
     7681 gggtgaatgg ctgccccgag gttcggttga tcagcaggga gctgtgaatg cccgtcgagg
     7741 ccccgtgtgg gcggtggaaa gatgcgggga gggccagaga ggggcgggaa gcgtggggcg
     7801 tggcgagcgg gacacagtcg cgaggggaac gcgactgtac gaggcggcgc aggcagtggt
     7861 cggtgaccat gcacgggcag tggaggcggt acgggcagcg ctgaaaccga tccacgatga
     7921 ggcggtgaag cgggagctcg acgccattcc cgtcgctcgg ctgcaggacg tcaccgaagg
     7981 gcggctgcgg ctggggagcg tcgagaagag cggactgcgc accctgggca gggttctcga
     8041 agcgggcccc taccggctgc ggcagattcc cggtgtcggg cagcgcaccg tcgaccagat
     8101 actcgccgcc gcccgccggc tttccgaggc cgtgcacgag accgtggccg tccacatcga
     8161 cgtggaccgg ccggaaccgc gcaccaccgc gctcgtcatg gccctgcacg tactggtgga
     8221 agccggcccg gaggcccggc gtgcggtcga caaggccacc gtcctgacgg aacggctcgg
     8281 tccgctgctg gccgacgctg ggcccgccgc cggaagggtc cggatgctgc tggccggccg
     8341 ggagaagaag gctcgcgcgt gggcggcggt cgccgcgacc cggtcgctgg tggacgaggc
     8401 ggagcaggcc ggcctgcccg ggctgctcgc ccaggcgtcg gtggacctgc tccgggggac
     8461 tgcgtccgac gttgcggcct gggtggactt cgaactccgc tccgccgagt actacagcct
     8521 gctcgccgag atctccggac ggccgccgga cgcggctgcc gtagaggggt tcttgccgga
     8581 cgaggttgca gagcgggtac ggacccagca cctcgacgac acgcaccggc gggtctccct
     8641 gcgcggctac caggcgttcg gcgcacggtt cgcgcttgcg cagcgcaagg tgatactcgg
     8701 cgacgagatg ggcctcggga aaaccatcca ggcgatcgcc gtcctcgccc acctggccgc
     8761 cgagggacag agtcacttca tggtcgtctg ccccgcgagc gtcctcgtga actggacacg
     8821 ggagatcgag gcccgcagtg ccctgcgcgt catggtgctc cacggtcccg accggcacta
     8881 cgcgttcgcc gactggaagg ggcggggtgg cgtcggggtg accacgttcg acgcgctgcg
     8941 cggctttccc gctccgggcg gcggggaggt cgggctgctg gtggtcgacg aagcgcactc
     9001 cgtgaagaac ccgaaggcca agcggtccca ggcggtcggt ctgtgggcgg agcgttgcga
     9061 gcgcacccta ttcatgaccg gaaccccgat ggagaacagg gtcgcggagt tccgcaacct
     9121 ggtccagatg ctcgacggcg atgtcgcgga ctccctcggt gaacgggacg cgttggccgg
     9181 atcggtcacc tttcgcaagg ctgtggcccc ggtctatctg cggcgcaacc aggaggacgt
     9241 gctgacggaa ctcccgagcc ttcagcagac cgacgagtgg gaggagttga gcgcttcgga
     9301 cgaggaggcg taccgcgaag ccgtgcgcgc gggcaacttc atggccatgc gcagggccgc
     9361 gtacatgagc tccgggaatt cggccaagct ggaacggctt cgggagattg ttcaggaggc
     9421 cggcgagaac gggcagaaga cggtggtctt ctccaacttc aaggacgtac tggccgtggt
     9481 gaaggaggcc ctcgcggtcg aaaccaccag ggtcactccg gtgttcggtc cgcttaccgg
     9541 cggcgtcccg gcccagcgcc gccaggagat cgtcgacgac ttcgccggtg tccagggtcc
     9601 ggcggtgctc ctggggcaga tccaggcagc gggtgtcggc ctcaacatgc aggccgcttc
     9661 cgtcgtcgtc atctgcgaac cccagatcaa gccgaccatc gagcatcagg cggtggcccg
     9721 ggcccaccgt atgggccagg tcaggccggt tcgagtgcac cgtctcctcg ccaccggggg
     9781 cgtggacgaa cgcatggtga agatgctgga ggccaagacg cgcctgttcg atgcctatgc
     9841 tcgccgcagc gccgtggccg aagccacccc ggacgcggtc gacgtgtcgg acaccgagct
     9901 ggcacgtcgg atcgtcgagg aggaacaggc tcgcctgggt atgacggacg agaggcccac
     9961 gtcatcggag tggggtgtcc cgcggtccgc agccagtccg caggaccccc tgaacggccg
    10021 tcgggagtcc acgaatgcca acgagtaatc ccaggtcagg gccatgcgtg gggctgtgcc
    10081 gcaggtcaga gtgtggcctc ggacgttccg cttccacgtc taaccggtga gccgcgtcac
    10141 tgcgcggacc cggtggcctg cagggcgtcg tcgagcaggt cgcgcagttg tgcgcgggcg
    10201 gtgatgccca gtttggggaa gacccggtag aggtgtgagc cgaccgtgcg cggggagagg
    10261 aacagcctct ccccgatctc gcggttggtc aggccgtggg ccgcgagccg gacgatctgt
    10321 tgctgctggg ggctgagttc ggtgagggcg ccgggtgcgg cggcgtccgc ctcgatgccg
    10381 gcggcccgca gttctgcctt cgcgcggtcg atccacggtc gggcgccgag tcgccggaac
    10441 gtgtcgaggg ctccggtgag cagcggtcgg gcctccgcca cacgacgctg ccggcgcagc
    10501 cactctccgt agtccagccg ggtctgcgcc cgctcgaagg gccactgctc gcccgcttcc
    10561 cccgccagcg ccgcccggaa gtggcgttcg gcacgctccg gttcggcgag cagggcgcgg
    10621 cctcgctcga ccagcaggaa gaggcgcgcc gacatgccgg ggcccaggtg ccgggccgag
    10681 cgctccagca gtcgcgcggc gggttcgcgg tgtcctcggc ggacggccgc cgcggcgagt
    10741 tcggccagga cggtggggga gacgtggtag tggaccaggt ctccgtcctc ggtgaaggcg
    10801 gcgcggaact gcgcgtacgc gctgtcgtag tcgccctcgg ccaccgccgc cagccccagg
    10861 gcacggcggg ccaggaccgc gacggagcgg ctctccaggg gggcgacgag ggccagcgcc
    10921 cgctcggcgc tgccgcgtgc ctcggccggt tcaccgagca gcgccagcac ggtcgcgtcg
    10981 agggtgcgtg cgcacgcctc ggcgtgatcc aggccggccc ctgaggccac ctccgcgatc
    11041 tcggcggcca ccgagcgggc gtcggcccag cggccctgct ccagataggc ccagccggcg
    11101 gcgcaggcca gaccggccgg cagcgggcca tgggcctgcc aacggccgaa cgcctcgtcg
    11161 aaggtcctgg ccgcgagcgg ggtccggtcg aggagccagg ccacgacggc gagcgccgtc
    11221 agtgacccgg cctcgccctt ggccgcggcg atcagccggg gcagcgccgg ggcgagggac
    11281 gctccggcgc cgctgggatc ggagacggcc agtacccagg cgcgcagcgc accacccgcg
    11341 gcggagtccg gcacatcggc gagcagggcc tcgatccgct gccgctggga ctcctcgccc
    11401 gagtagtagc ggaccaccgc cgccgcggcg agcgcgtcca gcagccgggg cgaccgggtg
    11461 gccgccgcct cgtcggcgac gcgcgacagc agtgcgaagg cggccgtgtg gtgcggaccc
    11521 agggtcagga gccgccccgt cgccagcgcg gcccggccga tcagcgccgg gtcgtcactg
    11581 cgctcccgtg ccccggcggc caggtgttcc acccagccga gctgaccggt gaagacggcc
    11641 gtgtccgcgg cgtcggccag cagtcgcgcc tggtccgccc ggtgcgggct gagttccgcg
    11701 gcgcgctcca gagcggcggc ggcggccgcg tgaccgcccc ggcgcctggc ccggcccgct
    11761 gtttcccgga gggccgccga cacctgctcg tcgggccgta cggccgcggc ggcgaggtgc
    11821 caggcgcggc ggtcgggctc ctcgcccagc tgccgggcga gggcgaggtg ggcccgcctg
    11881 cgctgctcga agggcgcggc gtggtagacc gccgagcgga cgagcgggtg gcggaaggag
    11941 accccggtgc cgtcctgccg tacgagaccg gcccgttcgg cgggcgccca caccgtgtcg
    12001 gccgcctcgg gcaggccccg tgcggccgcc ggggcgtccg ccgcgtcggc ggcggcgagc
    12061 agcagcaggg cgcggcgggt ggcttccggc aggtgccgca cgtggcgcgc gaagatcccc
    12121 tccagccggt cggtgacggg cagcgggccc tccactccac tgccctccgg ctctctgtcc
    12181 gccgtggcgc gggcgagttc gaccagggcc agcggattgc ccgccgcctc ccgcagaatc
    12241 cgggcccggg tacggccggt gggccgcttc ggctgctcgt cgagcagccg gttggccgcg
    12301 tcaccgctca acggcccgat ctccaggcgc tcgtagccct tgtcgaaccc gggcagtacg
    12361 gccgcggcac gcacgcccat cagcagcgtc acgggctcgc cggccatgcg ccgggccagg
    12421 aaggagagga cgtccagtga cgcgcggtcg atccactggg cgtcgtcgac caccacgagc
    12481 agcggtgccg gttcggacag gtccgacacc agggtcagca cggccaggcc gacgagcagg
    12541 gcgtcggggg tatcggcggc gtcttcggcg tcttcggcca gtcccagggc ggttcggagc
    12601 gcggagcgct ggcgggccgg caggccgccc aggtcatcca gcactgggcg gagcatctgg
    12661 tgcaggccgg cgaacgcgag agacgcctcg gactcgctgc ccaccgccct cagcacccgc
    12721 tggccggtac cgcgggtcag ccgcacggcg aggtcgagca ggacgctctt gccggcaccg
    12781 gggtcgcctt cgacgatcag taccgagctg tgggagcggt cggcggcgat gcggctcctg
    12841 atctccgcga tctcggcctc ccggcccacc acggtcggac cgggggcagg cgccgggccg
    12901 gggcccgcgg tcggaccggg ggccgccggc gagccgtggc ccgcgcgagc gcgttcacca
    12961 ttcttcacgg atgctccagg aactgagaca gccctgacgg caacgtggca ggaccgcggc
    13021 cgtattcctg ccgcccccgg ccgcacacgg tcgattacgg ctggtcaccg ccgctcaccg
    13081 ccgctcaccg ccgctcaccg ccgcacacca cgagcccggg cggacgccac gagcccgggc
    13141 ggacgccgcg agcccgggcg gacacgggtg cagtcacgtg acgcataccg ccgcccgcca
    13201 cccgcgacgc acccttgcgg aacaagggcg tgcgttcacg cccgaccttc tggagatctt
    13261 tcgaactgga gcaccccttg gacaccatca ccctgggcga tgtcaccgtg acccgggtcc
    13321 gggagtacta cggccccgtc ggcatgacgc ccgaggcgtt cgtcccggac agcccggccc
    13381 aggcgtggga cacgcaccgt tcctggctgg ttccggactt cctggacgcc gagacccgca
    13441 tcgtcaacac cgcgatccag acctgggtcc tgcgcagcga gggccggacc atcctggtcg
    13501 acaccggcgt cggcaaccac aaggaccggc cgtacgcgcc cgtctggagc cgcctcgaaa
    13561 cggactttct ggccaacctc gcacgggccg gcgttcagcc cgaggacgtg gacatcgtga
    13621 tcaacacgca tctccacatc gaccacgtcg gctggaacac ctacctggac ggccggacct
    13681 gggtaccgac gttccccaac gccacctacc tcatggccaa ggcggacttc gactactgga
    13741 acccggccaa cgagatcaag accctgctcg gccgcggcaa ccagaacgtc ttcgaggaca
    13801 gcgtcgcccc cgtgcacgag gccggtctca cccggctgtg ggaggacggc caccgcatcg
    13861 actccaacct gcgcctcgag ctcgcacccg gccacacccc cggctcgtcg gtgctgcggc
    13921 tggagtccgg ctccgaccgg ggcctgttcg tcggcgacct gatgcacagc ccgatccaga
    13981 tccacgagcc cgacgccaac agctgcttct gcgaggaccc cgccgaggcc cgtgccaccc
    14041 gccgccggct cctgggctcg gcggtggaca gcaacgccct cgtcttcccc gcgcacctgg
    14101 gcggccacgg cgctgccgaa gtcgtccgcg agggcggcaa gttcgccgtc aagggctggg
    14161 cgcccttcac cccgtacacc ccgtcggtct gaggcccgca aaaggacacg cgtgatgaac
    14221 caccaccccg agcccgtcgt gaccaccgcg cagggcgccg tccgcggcct gcgccaggag
    14281 gacggcaccg ccgccttcct caacatcccg tacgccgccc cgcccttggg cgccggccgg
    14341 ttcgcgcccc ccaggccgca cgagccgtgg gacggcgtac gggacgccac agtccccgga
    14401 cccaacgcgc cgcagtccga gcgcaggctc ggcagcatcg acatggcccc ctacttcggc
    14461 accggctgga gccgcggcga ggactacctc accgtcaacg tcttcacgcc cgccaccggg
    14521 gccggcgacc tgccggtcat ggtcttcgtg cacggcggcg gcttcgtcgc cggatcgaca
    14581 cggtccgcga tgtacgacgg ctccgccttc gcccgtgacg gcgtcgtcct cgtcaccctc
    14641 aactaccggc tcggcatcgc cgggttcctc gacatccccg gggcgcccgc caaccgcggc
    14701 ctgctcgacg tcgtcgccgc gctgcgctgg gtgcgggaga acgtctccgc cttcggcggg
    14761 aacccgcacc acgtcaccct cttcggccag tcggccgggg cgaccgtcgt cggcggcgtc
    14821 ctcgccaccc ccgaggccga cgggctgttc cggcgcgcga tcgtgcagag cggcagcggc
    14881 ctgggcgcgt tcacacccga gcaggccgcc cgcgtcaccg cggccgccgc ccaggccctg
    14941 ggcgtcgagc cgcacgtcga cgcgttcgcc ggcatccccg acgagcggct ggtcgaggcg
    15001 gcgtccgggc tcgcgggcat cgacctgcgg accgggaccc acttcgaccc gctgatcggc
    15061 ctcagcccct tcagcctggt cctcgacacc cagcccgccg catccgtcgc cgccggccgc
    15121 gccgccgacg tcgacctcct cgtcggcacc aacaccgaag agggcaacct ctacctggtc
    15181 ccggtgggca agtacgccac ctcgaccgcc gccgacgtcg acgaggccgc cgcacgtgca
    15241 caccccgacc cggcacagct cgtagcggcc taccgcacgt cacgccccga ggccaccttc
    15301 gcggaactgc gctccgccgt catggccgac gccctcttcg gcgcgggcag ccgcgcgctg
    15361 gcgagcgccc atgccaccca cccgcgggcc gccacctacg cctacgagtt cgcctggcgc
    15421 tcccgcgccc tggacggaga actcggcgcc acccacgcgg tcgaactgcc cttcgtcttc
    15481 gacctcgcgg accggcccga actcaacggc cccgccgccc tgctcggccc ggagcaggcc
    15541 cccgccgacc tcgccgcccg cgtccacgcg acctggatcc ggttcgcccg gaccggcgac
    15601 cccggctggg acccctacga caccgaccgc cgggccacca tgcgcatcga cgccgaatgg
    15661 agccagaccg acgacccccg cagcaaggaa cgggaggtgt ggagctgacc gcgggtcacc
    15721 cctgggggcg gggcccgggc gcgcccaggc ccccgagggc gatccccatg agccgggtgg
    15781 cgtggtgggc ggcgtcgggg gtgtgctcgg ccgcgaggga caccgcgttg gcgagggaga
    15841 gcagttcgag ggcggtcacg tcgtcgcgga cggttccgtc ttcctgggcg cgggccagca
    15901 ggtcggcgcc ggcctccgtc agcagttgct cacagcgcga atccagcgcg gcccccgtgt
    15961 tcgtgccggt cgccggcaac agggaacggg cggcgccgcg cgtgacggca ccgaagaccg
    16021 ccagggacgt cagccatcgc gtcagagcgg tcgccggcgg gtgttcggcc gccagggacc
    16081 gggcctcgtc gcacagctgt gccacgcgct cctggaagac ggcctggagc aggccccacc
    16141 gggaggggaa gtggcggtgc agggtggccg agccgacgcc ggcccgccgt gcgatctcct
    16201 ccagggaggc gtcggcaccg tgccgggcga cctcggccgc ggcggcctcg atgatccggt
    16261 cgtagttgcg gcgtgcgtcc gcgcgcttgg gcgggcccgg gttctcccag ctcacactcg
    16321 tggtcttctt cctcgccgac gaaacggggt gacaccccat tcttgcaccg ccgccgggct
    16381 gcgtcgtttg acaggaagtg gggggtggcc ccatattcga aaaagcggag gggcaccccg
    16441 tttctgccgc acgacacagg agacgaaggc atgcgcgccg tacagttcga ccgttttggc
    16501 ccgcccgacg ttctgcgcgt caacgacgtc cccgcgcccc gacccgggcc gggagaagtc
    16561 ctcgtcgagg tgcgcgccgc gagcgtggac gccggtgaga ccgccttccg ggcgggcagg
    16621 atgcgccggg tgacccgcgt ccgcttcccc cgcggcctgg gcagcgactt cgccggccgg
    16681 gtcgcggccc tcggcagcgg cgtacgcgcc tggagcgtgg gggacgcggt gtgggggctg
    16741 atgccgcacc tcaccttcgg ggcaatcgcc gactacgtcg cggtgcccga gcagcggctg
    16801 gcccgggctc cgcagaacct ggacctgctc gaagccgccg ccctgccggt ggtgggcacc
    16861 accgcgatga cggccctgag cggcaaggcg cgactccagc ccggggaacg gctcctggtc
    16921 cgcggcgcca ccggcggcgt cggcagcgtc gccgtgcagc tgggcaaggc gctgggcgcg
    16981 cacgtcaccg ccctcgccgc cgcccgcaac ctcgactgga tcacccggct gggggcggac
    17041 gaggccgtgg actaccgcac gacccggccc gaagacctcg accggttcga cgtgatcgtc
    17101 gacgtcgtcg gcaccgacct gggtgcctac cggaagcggc tggcccgcgg cggacgtctg
    17161 gtcgccctct ccttcgactc ggaccgcgtc gtctcctcca tgctcggcat cgccctgcgg
    17221 gcggccgcca ctccccggcg cgtcaagatg ttcagcaaca acccctcggc cgaccggatc
    17281 gccgaactca cccgggccgt cgaggcgggc acgatccggc cggtggtcga caccgtcttc
    17341 cccatgcggg acatagcggc ggtccaccag cggctcgaag ccggcggcgt ccgcggcaag
    17401 tacgtcgtcg acctgcggct tccctagctc acggtcggcc gatccccagg ttcggcgcgg
    17461 cagcgcgtca gggtgtcagc gcgcactccg ccgccgccac gaccgtgcgg gcctggagtt
    17521 ccacctgggc gtgcacgggg acccagcgca gccgcaggga cgtctcgaag tccgtgcacc
    17581 aggcggtgaa gagggcgtcc agctcgtggt ggagcccggc ggcggccggg gcgtcggccg
    17641 cgtgcagcag ccgcagcagg agtcccgccg cgcgtagcgg ctgacggcgc gcgacgacct
    17701 ccagggcgcc gatccccgcc gtcgtcaacg cgggtgagcc gtcggtgcgc ggtcccgcct
    17761 ccgcctgccg gaccaggggc ccccaggagt cggccaccag gtcgtacagg tcctcggcca
    17821 tccactccag tacgcgtacg ggtgggctgt cctcgggtgc cggcaggagg ccgcgggccc
    17881 tctcgaacac ggcggtcacc tgccggccgc cctcccgcac cagcccggac agcgcgcgca
    17941 gggcccgggc ggggtccgcg tgcggggtcg ggtcgtccgc cggggcggtg gcccacagcg
    18001 gtacctcgac gatcgccgtg gcaccgccgt accgctgggg cgcgcaccag gtggacaggc
    18061 cgatgtcctc ggacccggcc gccggccgcg cggtgctgcc cggcggcggc aggacatgga
    18121 tgccgggggc cggattctcc cagtacaggg cgtcgtacgt gccgtgctgg accgggaccc
    18181 ccagggcggc ggcggacgcc gcgaaggggg cggcgagtcc ggggaggtcg cgggtcagct
    18241 gggcccaggt gccgcccgcg tcgacgttgt gcagggagca ctggaggacg gggcgcaggt
    18301 cgtcgatcac gtcgaacagg gcacggctct ccgggagtgg ccggccgacg atcggggccc
    18361 actccggctg ctccgcggcg accgggcgga aggcggcacg gtagtacgac gccagggacg
    18421 gggcggggcc ggccgtcgcg gtctcgatgc cctcgctcag cgcggcgccg tccgggtcga
    18481 ggcacaggac gatgtcccag gtgacggcct cggggtcggt cgccggggag cgccggtcgc
    18541 cgcctgcgac cagctccgcc agcgccagtg ccgtcgcgcc gcccaccggc tcgtccgggt
    18601 gcggccgggc caccaccagg acgtgccggg gtccgtggcc caccgacagc atcaggagcg
    18661 gccggcccgc ccgggacgtg ccgacacgac acaggcggcc ggtgcccggg aaacgggaga
    18721 ccagccgtcg cgccgactcg gtgacctccg cgaccgtggg gtatcggttc atcgggcgtg
    18781 tccggtcagg ctccgccgtt gccgctctcg tccgccatgc cgtctccttc cgacggtgcc
    18841 cgtgggtacc cgtgggtacc tgtgctgctt ttcgcgcctg tgctgcctgt ggtgtgcgag
    18901 gcgcgtcgtg ccgctgtcag cgtccgttca ccggatcacc gctgtcaatg gccggtgccg
    18961 cccgcgcagt cgggggcggc gaagccggcg cgaaggcgag ggtgcgcgtc aggccgggaa
    19021 gacgtggtca tgggtgacgt ggcgggagcg cagcagcaac tcgccgtccg ccccccggac
    19081 caggacgtcg tgcacgaggc aactcggccc gaactccggc gccttgacgt cggcgtggac
    19141 ggtgagcacc aggcagtagc tggtcgccgt gatcgagccg tcggacgcct ggctcagcgc
    19201 cgtgtggtcg aaccagtgcc tgcgctggat tttgcgggcg tcgaacttgc ggtggaagtc
    19261 ctccaggacg gcggtgatcc cggcacgggt gtgggcggca ggcagcgagg gcgagtgcct
    19321 gaactcgccg tcctcggtga aggtcgcggc gtagccggcg aagtcacggc cgtccagctt
    19381 ctgcatctgg tggccgtaga acgacaggac ctcggcgtac aggccggtgg gaagcgcggt
    19441 gatggtcata cggccacggt cgcccggtgg cctcgaagtt ccctcgagcc gggttcgagt
    19501 gggcgctgcc aggctcgtcg ccatgagcac cgtgacagtg atcggggcgg gcacgatcgg
    19561 cctgggatgg atcaacctgt tcagcgcccg cgggctgacc gtacgcgtca acagccgtcg
    19621 gcccgacgtc cggcgcgtcg tgcacgaggc gctcgagctg ttctccccgg ggcgggtgga
    19681 cgagctggcg gcgcgcatcg agtacgagcc ggacgtcggc cgggcggtgg ccggggcgga
    19741 cgtcgtctcc gagaacgccc ccgacgacct gccgctcaag cagcggttgt tcgcagagat
    19801 cggagcggcc gccccggacc acgccctcgt gctgtcctcg acgtcgaagc tgcttcccga
    19861 cgagctgagt cgggacatgc cgggaccggg ccggctggtc gtcgcgcatc cgttcaaccc
    19921 accgcacatc gttccgctgg tcgaggtggt ccgcggcgag cgcaccgacc cggaggccgt
    19981 cgaacggaca ctggccttcc tggcgtcggt cgggcggacc cccgtcgtgg tgcgcagggc
    20041 gctgcccggc ttcgcggcca accggctgca gtcggcgctg ctgcgcgaga gcatccacct
    20101 cgtcctcgaa ggcgtggtga ccgtcgagga gctcgaccgg atcgtcaccg actcgatcgg
    20161 cctgcgctgg tccaccatcg ggccgttcca cgcgttccac ctgggcggcg gtcccggcgg
    20221 cctgcgcaag tggctcgagc acctcggcag cggcctcgaa cagggctggc gtgggctcgg
    20281 acagcccgcc ctcaccccgc aggccgtcga ggctctggtc gcacagaccg aagccgccta
    20341 cggacaccgg ccctacgccg aactggtccg ggaccgtgac gaccggcacc tcgccgtact
    20401 ggccgccctg gagcggaccg agcagcccca ggaggagacc aagtgatgcg tgccgtgcag
    20461 ttcgaccggt acggggaccc cgacgtgctg tacgtcgccg agcgtcccgt ccccgaaccc
    20521 ggccccggcc aggtgagaat cgccgtcgac gccgtgagcg tcggccacgc gcagacccag
    20581 atgcggcgcg aggccttccc cgcgccgatg tggcggcccg tcttccccgt cgtcctcggc
    20641 ggcgacgtgg tcggcaggat caccgcggtg ggaccgggcg tcacggccct gcggccggga
    20701 gaccgggtcg gtgcgttcac cctctacggc gcctacgccg agcaggtcgt cgtcgacgcc
    20761 gtcaccgtcg tacccgtgcc cgaggagctg gacgccgccg aggccgcggt cctcccgggc
    20821 accggactga tcgccctcgg catcctgcgg accggacgac tgcgcaaggg cgagacggtg
    20881 ctgatccacg cggcggccgg cggggtgggc cacatcgcgg tccagctcgc ccgggcggcc
    20941 ggcgccggcc tgatcatcgg caccgcgggc gcggccgcca aacgcgagtt cgcccgcgcg
    21001 acgggcgccg acgccgtcgt cgaccaccgc tccgcacact gggccgacga ggtccgggaa
    21061 ctcaccgggg ggcgtggccc cgacctgatc ctggacggca tcggcgccga ggtcctggag
    21121 cagggagtcg gtctgctcgc tccgggcggc cggctggtgt tctacggctc gtccggcggc
    21181 gagctggcga tcccgaaggt gtcggtgatg gacctcatcg gcatcaagta cgtcaccggc
    21241 ttcgccctgt cggcctggcg cggtggccgc ccgcaggagt acgaggcggg cgtcgccgaa
    21301 ctcacccgac tgctggccga aggacaggtc acgtccgcgg tgcacgcccg gctgccgctg
    21361 gagcgggcgg ccgaggcgca cgccgtcgtc gaggccaggg cccagctggg ccgggtcgtg
    21421 ctcgtcccct gaaacgacca ggcattcctc cgaagtgtcc aagcattcct gatccaagag
    21481 cccgaaggag acctttccat gacctcgtcg ctgcaccacg cgatacgtct gaccaccgcg
    21541 tccgccatcg ccctgggcgg actcgtgacc ctggggacca gcgcgcacgc cgcgagcgtc
    21601 gccgtgccgt acgagtgccg cacctgggtg cagggcaaca cgcacccggt ctacgactac
    21661 gcgcgcggct tcgacgtcag cgtgcccgcc tcggtccgcg cgggcaagaa gttcaaggcc
    21721 acctacgatc ccgacccgat caccgccttc gccgagtaca accagatcgt caacgacgtg
    21781 cggatcgcct accggatccc ggacggcgcg aaggtccaca aggtgcggct caccggcggc
    21841 agcggtctcg gcgactccga cgtccgggtc caggtcaagg gccgggacat cgtcgtcagc
    21901 gcctccggcc ccttccaggg cggtgtcgag ttcgacctgc cgacgctgaa ggtcacctac
    21961 aaggcgccga agaccaccgg cccgctcaac ttcgtctcgg gcggctcggg ttacgaggac
    22021 cccggcttct actggtaccg ctaccagccg atcctggacg agtggggccc cttcgagtgc
    22081 ttccccgacc cggcgaagcc cgaggccgtc ctggccagca cccaggtcaa gaagcacaag
    22141 tagacacagc ggggtcggac gaacaatgga gaacgcatgc ccaaggccgt agccatccac
    22201 cagttcggcg ggccggacgt actgggcctc gtcgatgtcc ccgagccggt gccgggaccg
    22261 ggccaggtga ccgtccgagt gcgggccgcc ggagtcaacg ggttcgactg ccgggtgcgc
    22321 tccggcggca tgcgcggtcg ctatccggtc gagttcccgc agatcatcgg caacgagttc
    22381 gccggggtcg tcgagcggac cggaccggag gcgaccgggt tcgcgcccgg cgacgaggtg
    22441 ctcgggttcg ccgtgcttca gtccggcacc gagctgctcg ccgtcggcgc ggaccagatc
    22501 accgtgaaac cgccggagct gtcgtgggag gtcgcgggat ccctctcggc cgtcggacag
    22561 accgccgaca tcgccctggc cgaactgcgg gtcggccccg gggacaccgt gctcgtgcac
    22621 gccgcggccg gcggcgtcgg cagcctcgcc gtccagctcg tccgggagcg gggcggcacg
    22681 gcgatcggca gcgccggcga gcacaaccac gactacctgc ggtcgttggg cgcactgccc
    22741 gtcgcctacg gcccgggctt cgccgaccgg gtgcgggccc tggccccgaa cggcgtcgac
    22801 gccgccctcg actgccacgg cggaccggaa gccctcgccg tgtcgctcga actcgtcgcg
    22861 gaccgggccc ggatcgccac cgtcgccaac ttccgcgccg cggcccagga gggcatcgtc
    22921 atgccacggg tggtgcggtc cgccgagcgg ctcgccgcgc tggccgcact ctgcgccgag
    22981 ggccggctgc ggccgcacgt cgaggccgtc ctgcccttcg ccaaggcggc cgaggcccat
    23041 caccggctgg agcagggcca tgtccggggc aagctcgtcc tggtgccgga cctgtgacgg
    23101 cgaaccccgg ccgtccgggc ggcccggcgg accagggcca cccgcgccgc tgggccatcc
    23161 tcggggtgct ggtcctcagc ctggtcggca tcatcctcga caacaccgtg ctcaacgtga
    23221 cgctgcgcac cctcaccgac cccgagcagg gcctgggcgc ctcgcacagc caggtggaat
    23281 gggtgctcag cgcctacacc ctggccttcg cggcgacgct gttcacctgg ggagtgctgg
    23341 gcgaccgact gggccgcagg cgggtactcc tgctgggcct cggcctgttc ggactgtcgt
    23401 ccctggccgg ggcctacgcc gggtcgccgg agcagctcat cgccgcccgt gcctgcatgg
    23461 gggtgagcgg cgcggcggtg ctgccgagca cactcgccac catcgccgcc gtcttcccgc
    23521 tgcgcgagcg gcccaaggcc ctcgggatct gggcggcctc ggtcggcttc gccctcggca
    23581 tcgggcccgt caccggcggg atactgctcg cgcacttctg gtggggctcg gtcctgctgg
    23641 tcaacgtgcc cctcatggcc gggtgcctgg tcgcggtggt gctggtggtg cccgagaccc
    23701 ggggcacggc gggcaggcgc gtcgacgcgg ccggactgct gctctcgatc gcgggtgtcg
    23761 tgccgctcgt ctacgcgatc atcgaggccg gccggagcgg cggggtcacc cggcccgcgg
    23821 tctgggcagc cggcctggcg ggcctcggcc tgctcctcgt gttcctgtgg cacgagcgcc
    23881 gtaccccgga accctcgctg gagctcggct tcttccggat gaaggccttc tccaccgccg
    23941 tcgcggccgt cggcttcgtc agcttcgcga tgatgggctt cctcttcttc agcgccttct
    24001 acctgcagag cgtgcgcggc tacacacccc tgcaggccgg gggatgcacc gtggcactgg
    24061 ccgtcgcgaa cgtggtctgc ggaccgctca gcacggtcct ggtgcgttcg atcggccccc
    24121 ggaacgtgtg cgcggcgggc atgctggccg tcaccgcatc gctctgcggg gtcaccttcg
    24181 tgacccagca cgcacccgta tggctgatcc tcgtcctgtt cgccgcgctg ggggcgggcg
    24241 tagcatgcgt catgccgacc gcggccgtgt ccatcatgaa cgcgatccca cgcgagaagg
    24301 cgggcgtcgc ctcggcgatg aacaacaccg tgcgccagct gggcggcgcc ctgggcgtcg
    24361 cggtgctcgg ttccctcatg ggcgccgcgt accgccgcgg catcgaggac gagctcgccg
    24421 tactgccgcc ctccgcgcgg caccaggccg gcgagtccct ggatgccacc ctgctggccg
    24481 cgactaggct gggggagagc ggacttgtcg gccccgcgcg ccaggcattc ctggacgcca
    24541 tgcacctggc cgccggggcc gctgccgcgg tggcgctcgt gggggccctt gccgtgctcc
    24601 gctggctgcc ctcctccgtc acgactccga cgcccccggc aggggccgtg cccggccggg
    24661 agcattccga tcacctcaag gtccaaggaa gctgacatgc ctttcactcc tgacgagctc
    24721 gagtactacg cctcccagaa cctcggccgg ctggccaccg tggcgcccga cggccagccc
    24781 caggccaacc cggtctcgtt ccgcgtcaac accgagaccg gcacgatcga catcggcggg
    24841 cacaacctga ccgccagcaa gaagttccgc aacgtcacca agcacgacca ggtcgccttc
    24901 gtcgtcgacg acctgatctc cacgcagccg tggaacgtac gcggtatcga agtgcgcggc
    24961 cgggccgagg cgctgaccga cgcgcagccg ccgcacccct acttcggtac cgcgatgatc
    25021 cgtatccacc ccaagcgcat catcacctgg ggcctcggcg gcgacgccgc ccagcgcggc
    25081 cgcgacgtct gacccagcac ccttcgactc cgcttcgagc ggacctcgac gccctcttgc
    25141 caaggtggag cccgtaggac gggtacacca cggggagggc ggctggatga gtacagagat
    25201 cttccatgag gagttcgccg gggggctggt gaccgagggg ccgggcgcgc cgtggcggct
    25261 tcgcccggtc gacggtctcg aggcgggaga cgggctggtc cgcgggggac cggacggcct
    25321 ggtggtcgtg ccgagcgccg cccacccggg gacccggcgg ccggcgttca ccgagcccaa
    25381 gcccgggccg gacggcaccc cgctgcatct gcggtggggt gccttcacca ccggcggcac
    25441 caccggcggc accgccggcg cgcgggcggc gttcaccgcc gtgcccggcg aacggctctc
    25501 ggtcagggcc gagatggggc tgcgcggctt cggtctgcgc tcccatccgt acgacgacgt
    25561 gaccgaaccc gacgcggacg cccggctcgg cgcgggcggt ctgatctcgg tcgatctcga
    25621 gtccgggatc atcttcgact tcttcctcac acacagccgg ctctacgcgg tctacgagcg
    25681 gctcgcgctg cggccggacg ccgagttcgc ggccttcacc tactgcgtcc cggtcgcgga
    25741 ccgcaccccc ggcacgctcc accggctcga ggtcggatac gacgtcgcgg ccggcaccgc
    25801 ccactggacg gccgacgggc aggaggtcct gtccgtggac cggatcggct tccgcgcact
    25861 ggacgcgcgc tggctccggc gggacaacgg cggccgcgag gaggccgtac ggccgcgcgg
    25921 actcagcttc ggcctcgggc tcttcctgga gcgccacttc ggccaggggg tgcggctgtc
    25981 ggtgcgaagg ctgtcggtgc tcacctcgcc cgccggctcc cgcgactcgt gacgacgacc
    26041 aacgaaaggc actgcgatgc ccgatgagaa caagcccgta ctggtcctcg gcgccaccgg
    26101 aaagcaaggc ggctccgcgg cccggtacct gctggaacgc ggctggacag tccgggcctt
    26161 cgtccgggac cccggcgcgc ccaaggccaa ggagctgcgt gagctggggg cgagcctgca
    26221 caccggcgac ctggaggacg ccggctcggt gcgcgccgcg atgaagggtg cgtacggcgt
    26281 gttcagcatc caaacgccga tgacaccggc cggcgtggag ggcgaggagc ggcagggcaa
    26341 gatatgcgcc gacgccgccc gcgacctcgg cgtccagcac tacgtccaca gctcggtggg
    26401 cggcgcggaa cggccggagg gcgtgaactg gcggctgtcc aagctcgcga tcgagcagcg
    26461 gatccaggag aacgcgctcc ggttcacctt cctgcggccg tcgtacttca tggagaacct
    26521 gaaccacgac atgtcgcccc tcgtcatgga ggacggcgtg ctgaccttcc ggagggggct
    26581 cgggccggcc aacaccctgc agatgatcag cggccccgac atcgggtact tcgcggccga
    26641 cgccttcgac gaccccgaca ccttcggcgg cgccaagatc gagctggccg gggacgagct
    26701 gaccggcgag cagatcgcgg ccgcgttcgg ccggcacacc gggctgcccg cccgcttcgt
    26761 gtcggtgccg ataccggagc tgcaccgcac ggggttcgag tggcaggcga tctcgtacac
    26821 ctggctcaac ggcatcggct atcacgccga catccccacg ctgcgcgccc ggttcccgca
    26881 gctgctcacc ctcgaccagt ggctggccag gaccggctgg accccgaggg acccggcatg
    26941 agcgaggaca cgatgaccca ggagcggccg tccctgacgg cacacgcccg ccggatcgcc
    27001 gaactcgccg ggaagcgggc ggccgacgcc gaacagcagc gccggctgag ccccgacgtc
    27061 gtcgacgcgg tccttcgagc cggtttcgcc gcccacttcg taccggtggc gcacggcggc
    27121 cgggccgcga cgttcgggga gctggtggag cccgtcgcgg tgctcggcga ggcctgtgcc
    27181 tcgaccgcct ggtacgcctc gctcacggcg agcctcggcc ggatggccgc ctacctgccg
    27241 gacgagggcc aggccgagct gtggtccgac ggccccgacg ccctgatcgt cggtgccctg
    27301 atgccgctgg gccgggccga gaagaccccg ggcggctggc acgtgtcggg cacctggccg
    27361 ttcgtcagcg tcgtggatca ctccgactgg gcgctgatct gcgccaaggt cggcgaggag
    27421 ccgtggttct tcgcggtgcc gcgacaggag tacgggatcg tcgacagctg gtacccgatg
    27481 ggtatgcgcg gaacgggcag caacacgctc gtcctcgacg gggtgttcgt gccggatgcg
    27541 cgggcctgca cccgtgcggc catcgcggca ggtctcggtc cggatgccga ggcgatctgt
    27601 cacaccgtgc ccatgagggc ggtcaacggg ctggccttcg cactgccgat gctcggcgcg
    27661 gcccgcgggg ccgcggccgt gtggacctcg tggaccgccg gaagactggc cgggccgacc
    27721 gggcagaacg ccgtctcgtc ccaggaccgc gtggtgtacg agcacacgct ggcccgggcc
    27781 acgggtgaga tcgacgcggc ccagctgctg ttggagcggg tcgcggcggt cgccgacgcc
    27841 ggctcggcga ccggcgtact ggtcggccgc ggggcgcggg actgcgccct ggcggcggag
    27901 ctgctgaccg ccgcgaccga ccggctgttc gcctcggcgg gcacccgggc acaggcccag
    27961 gacagcccga tgcagcgcct gtggcgcgat gtgcacgcgg cgggcagcca tatcgggctg
    28021 cagttcgggc ccggggcggc gctgtacgcc ggagagctgt tgaggaggag caacgatggc
    28081 tgaagtgaac gatccccggg tgggcttcgt cgcggtcgtc accttcccgg tggacggccc
    28141 cgccacccag cacaagctgg tggagctggc caccggcggg gtgcaggagt ggatccgcga
    28201 ggtgcccggc ttcctgtcgg ccacgtatca cgcgagcacg gacgggaccg cggtcgtcaa
    28261 ctacgcccag tgggagagcg agcaggccta ccgggtgaac ttcggcgccg acccgcgctc
    28321 ggcggagctg cgggaggcgc tgagctcgct gcccgggctc atggggccgc cgaaggccgt
    28381 gttcatgact ccgcgggggg cgatcctgcc gtcctgacct ggtcgtccgc ggcctcgccg
    28441 gccccggcca gcaggccggc gatgatgatc tcgaggccga gctcgaaccg gcggtcggag
    28501 tcgagcgagg tgatcgggcc ggccaggtgg accaggttcg ggaaactggt ggccggcagt
    28561 gacttcaggt agccgtggag ctggtcggcg aacacgccgg cctgctcccg gccctgttcc
    28621 gttccggggt tgcgggacga ctgctccagg gcctccgccg tgacgaaggt cgacagcagg
    28681 tcgcccccgt aggcggcgag ttcgtcgtgc aggcccccgg agcgcagcag gttcatggtg
    28741 cgctccatcc ccaccatccc gttgggtccc agcggcaccc ggtcgatcgc gatccgtgcc
    28801 aggtcccggt gggccaggaa catcctccgc agcgaccggc acatctcctt gacctgctcc
    28861 gcccagcggc cgggttccgg ttccgggacc tccacctcgg tcagcacgat gtcgaagacg
    28921 aggtcgagca gctcgtcccg gttccccacg tgcgcgtaca gcgaggcgtg tccggtcttc
    28981 agctcctgcg cgagccgccg catgctcagg gcgtcgagtc cctcggcgtc gaggatgccg
    29041 agcgccgtga cgacgatccg gtcctgggtc aggggcatgc gcggcggcgc cttcttcggc
    29101 cggcgccacg gaggcacggg aatctcctcg ggcatgggcc tcccttcctc gcttcgcgac
    29161 acgtgctcct catcgtatgg catgaacggg ccaccgtttc ttgacgcgac caccgttcca
    29221 ttgtagaacg gtggtcgttc gtggaccaat agtcgaggac ccgggggacg ccatgagttc
    29281 cgttgaagcc gacgagccgg acagggccac ggccccgccg tcggcgttac tgcccgagga
    29341 cggccccgga ccggacggaa ccgcggccgg acccccgccc tacgcgcgcc gttgggccgc
    29401 gctgggagtc atcctcggcg ccgagatcat ggacctgctc gacggcacgg tcatgaacgt
    29461 ggccgcgccc gccgtccgcg cggacctggg cggcagcctc agcgtcatcc agtggatcac
    29521 cgtcgggtac acgctcgcgt tcgccgtcct gctcgtggtg ggcggccggc tgggcgacat
    29581 ctacggccgc aagcgcatgt tcgtcgtcgg cgccgtcggc ttcaccgcgg cctccgtgct
    29641 gtgctcggtg gcggccggtc ccgagatgct caccgcggca cgcttccttc agggcgggct
    29701 cggcgcgctg atgattccgc aagggctcgg tctcatcaag caaatgttcc cgcccaagga
    29761 gacggcggcg gcgttcggcg cgttcggacc cgccatcggg ctgggcgccg tgctcggccc
    29821 gatcgtcgcc gggttcctgg tcgacgccga cctgttcggc acgggctggc ggtccgtctt
    29881 cctgatcaat ctgccgatcg gcgtggccgt gatcgtcggc gcggtcctgc tgctgcccga
    29941 gggcaaggcg cccgtgcggc cgaagttcga cgtcgtcggc atggcgctgg tgacgtccgg
    30001 gctcaccctg ctcatcttcc cgctcgtcca ggggcgcgaa cgcggctggc ccgcctgggc
    30061 gttcgtgctg atgctggccg gagcggccgt gctcgtcggc ttcgtcgccc acgaactgcg
    30121 gcaggagagg cgcggcggcg ccacgctcat cgagctcagc ctgctgcgca ggtcccgcta
    30181 cgccgcggga ctggcggtgg cactggtgtt cttcaccggc gtctccggaa tgtcgctgct
    30241 gctcgccctg cacctgcaga tcggcctggg cttcagcccc accagggccg cgctgaccat
    30301 gacgccctgg tcggtgttcc tcgtcgtcgg cgcgatcctg accggggcgg tgctgggatc
    30361 gaagttcggc cgcaaggccc tgcacggcgg gctcgtggtg ctggcgctgg gcgtgctgat
    30421 catgctgttg acgatcggcg accaggccgg cgggctgacc agctgggagc tcgtccccgg
    30481 tatcgccgtt gccgggctcg gcatgggcat catgatcgga ctgctcttcg acatcgccct
    30541 ggccgacgtc gacaagcagg aggccggtac cgcctccggc gtcctcaccg cggtccagca
    30601 gctcggcttc accgtgggcg tcgcggtgct cgggaccctg ttcttcgggc tgctcggctc
    30661 acaggccacg gcgagcgtcg acgacggcgc gagccgggcc cgcaccgaac tcgccgccgc
    30721 cggggcgagc acgaccgagc aggaccggct cctggccgac ctgcgggtgt gcctgcggga
    30781 atcggcgagt cagcaggact ccgaacggac gccggacagc tgccgaaacc tccagcaggc
    30841 ccggccggcg gtggccgagg ccacggcgcg ggcctggcgg acggcccaca ccgagaactt
    30901 cagcaccgcg atggtccgca cgctctgggt ggtgatcgca ctgctggcgg tctccttcgc
    30961 gctggccttc cggctgccgc ccaagccgcg tgaggaagag ggcttctgat gacacgcaca
    31021 ctgctgtcct ggcccggcgg acgccggctc aagtggctgg tgctcgcggc ctggatcggt
    31081 ctgctgatcg tgctccagcc gctggcaggg aagctcggcg acgtcgagtc caacgacgcc
    31141 gccgcctggc tccccggcaa tgcggagtcg accgaagtgc tcgagctgtc cgagaagttc
    31201 cagccggccg acaccagccc gaccgtgatc gtctacgacc gcccgtccgg gatcacggcc
    31261 gccgacgagg cgaaggcgcg ggccgacgcc acgcacttcg cggacggcac cggtgtggtg
    31321 ggcgagccct acggcccggt gcgctcggac gacggcaagg ccctgcgcac cgtcgtcaac
    31381 gtccacctcg gcaaggacgg ctgggagggg ctcaacgcgg ccgcgaagga catgcgggcg
    31441 atcgcccggc cgagcgcccc ggacggtctc ggcgtccacg tcacgggtcc gaccggttac
    31501 gccgccgatt ccgcagagtc cttcagcagc gccgacttca agctcaccct ggtcaccctc
    31561 ctcatcgtcg tgacgatcct cgtcgtcacc tatcgcagtc ccttgctctg gctgctgccg
    31621 atgatctccg cgggcatgtc cctggtcatc tcgcaggcca tcgtctacct gctggccaag
    31681 aacgcgggac tcacggtcaa cgcccagacg gcgatgatcc tcacggtcct ggtgctcggc
    31741 gcggccaccg actacgcgct gttgctcgtc gcccgctacc gcgaggagct gcggcggcac
    31801 gaggaccggc acgaggccat ggccgtggcg ctgcgccggg ccggtcccgc catcgtggcc
    31861 agcgccgcca ccgtcgccgt cagcatgctc gtcctgctgc tggccgctct gaactccacc
    31921 aagggtctcg gcccggtctg cgccgtcggc gtgctggtcg gcctgctgtc gatgatgacg
    31981 ttgctgcccg ccctgctggt gatcttcgga cgctgggtct tctggccggc ccggccgaag
    32041 cacggtacgg agcccgacgt cacccggggt ctgtggtcgc ggatcgcccg gctggtgtcc
    32101 ggccgtccgc gtgccgtctg ggtcaccacc agcctgctgc tgggggcggt ggccacgctg
    32161 gccgtcaccc tgaacgccga cggcctccag cagaaggacg gtttcaagac caagccggag
    32221 tcggtggtgg gcgaggagat cctgacccgg cacttcccgg ccggctccgg tgaacccatg
    32281 gtcgtcatcg ccaagggcgc ctcggcggac caggtgcacg cagctctgga gaccgtgccc
    32341 ggcgtcatcg aggtcgcacc accacaggtg aaggacggcc tcgcctatgt cgaggcgacg
    32401 ctcggcgccg gggcggactc gccggcggcc atgcgttcgg tcaccgcggc ccgcgagaca
    32461 ctcgcccggc tggacggtgc gcaggcacgg gtgggcggca gcagcgccgt cgtgcacgac
    32521 atgcgggagg cgtccagccg cgaccgcggt ctgatcattc cggtgatcct cgccgtggtg
    32581 ttctgcatcc tcgcgctgct gctgcgagca ctggtggcgc cgctgctgct gatcgcgagc
    32641 gtggtgctgt ccttcttcac cgcgctcggc ctcgccgccc tcttcttcaa ccacgtcttc
    32701 gacttcgcgg gagccgattc ggccttcccc ctgtgggtct tcgtcttcct ggtcgccctg
    32761 ggcgtcgact acaacatctt cctcgtcacc cggatcaagg aggagagcga ccggctcggc
    32821 acccggcagg gcgcgctcaa gggcctcacc tcgaccggtg gcgtgatcac cgcggccggg
    32881 ctggtgctgg ccgggacctt cgccgcgctg gccacgctgc cgctggtctt catcgccgag
    32941 ctcggattca cggtcgcggt gggcgtcctg ctcgacacca tgatcgtgcg atcggtcctg
    33001 gtcaccgcgc tcactctcga tgtcggccgg tggatgtggt ggccgcaccc gctcgcccgg
    33061 cgcgaggacc cttccgagga cccagccgta tcaggaatgc cagattctat tgattcggaa
    33121 gcctcgacca ctgcctctcg gtaaaatcca gcaaaaatta atcagtgcag ctcgctgcac
    33181 tgattaattt ttgatcaata ggagatcgct tgtgacggca agcacattga aatctgttga
    33241 gtaggcctgt tattgtcgcc cccaggagac ggagaatctc gacgggggcg cagatgagat
    33301 tcaacttatt gggacgtgtc catgtaatca ccgatgcggg atgtgtaatt ccgcttaaat
    33361 cctcgaaggc gacccagctc ctggtgctgc tgctcctcag gcggcacgag gtggtgggat
    33421 cgggggtgct catcgaggag ttgtgggcgg accacccgcc ccgcagcgcc atgacgacgc
    33481 tgcagacgta cgtgtaccac acccgccggc tgctggggga gcaccgggtg acgagcgacg
    33541 accgggaatt ggtcctgacc cagccgcccg gctacttcgc cctgatcgac gaggacgaac
    33601 tcgacgtcgc ggtcgccgag cgtctgatcc gcaccggcgg ccggctgctc gaggagaacc
    33661 ggctcgagga ggcgctcgcc tcgttggacg cgggactgga tctctggcga ggcccggcgc
    33721 tgtccaccgt accgtgcggc cgggtgctcg aaagcaatat cgcgcacctg gaagagctgc
    33781 ggctttttgg aatgcagctc cgtatcgacg cgaattggcg gctgggcaga atagggccga
    33841 tgattccgga actccggtcc ctggtaattt cgcatccgct gaacgagacc ctgcacgcca
    33901 aactgatggg cgcgctctgt cagatgggca ggcgcgccga ggcgctggaa tcgtatcgga
    33961 atctccggcg gatactgtcc gacgaactgg gggtggatcc gacgccggaa atccagcgta
    34021 tgcacatgga aattctcaac ggtgagaagg tgctcgtgta gcaccggtcc gtgaacgcgg
    34081 tggagcccct cgcagcctgc gaggggctcc accgcgttca cggaccggcc ggcgtcagta
    34141 gttccccagc ccgccgcaga cgttcagcgc ctgcgcggtg accgcggccg caccgggccc
    34201 gatcaggtac gccaccatct ccgccacctc ggacggctgc acgtaccggc cgatcggcac
    34261 gcgcgcggtg atccggtcga aggcctcctc ggtcgacacc tcccagatgt ccgagtagtg
    34321 ctcgcgcacg gacgcggcca tcggcgtctc gacgaatccg gggcagacgg cgttcaccgt
    34381 gatgccggtc ctcgccagtt cgagaccgag cgccttggtg aagccgacca cgccgtgctt
    34441 cgaggcggag tagggcgcgg cgtgcaccac accctgcttt ccgccggtcg aggcgatgtt
    34501 gacgattcgg cccgtgcccc gttcgagcat gccgcccgcc ttgaggacct gtttggtcac
    34561 ccggaacacg ccggtgaggt tggtctccac gacatcgagc cagagttcgt cggcgagttc
    34621 ggccgtggcg ccgccgccgg gccggcccgc gttgttcacc agcacgtcga ccggaccgta
    34681 acgctcgacc accgccgcca cgagagcctc gatctccggg accgagcgga cgtcgcaggt
    34741 ccgcccgtcc gcctccacgc ccgcctcccg caactccttc agcgtcgtcc gcagtccttc
    34801 ttcgccgcgc gcgcagacga acacgcgcaa cccctcctta ccgagcctgc gggcgatctc
    34861 cagcccgatt ccgctggtcg cacccgtcac cagtgcgact tcggagtcct gcgtggccat
    34921 gtgttcccct ccctgcctcg tggtccctca cgcgctcagc tttgggcgcc cggctcgagc
    34981 ggcggtcgaa gggagatggg gtgccgctgg acgcggcgcc ggtggatccg gcatcgaggg
    35041 gtcccgtatc ggccttcgag cctccttcga gccacggggc cgacgatgac gacgaccacc
    35101 ggacgaacgc atcgaaggag ctgttcggat tgaagcgcag agtcgtcatc acgggcgtcg
    35161 gcgtccgcgc ccccggcggg aacggcaccc ggcagttctg ggaactgctc acctcggggc
    35221 ggacggcgac gcgccggatc tcgttcttcg acccctcgcc ctaccgttca caggtcgcgg
    35281 cggaggccga cttcgacccg gtcgccgagg gcttcggccc gcgggagctc gaccggatgg
    35341 accgggcctc gcagttcgcc gtggcctgtg cccgggaggc gttcgccgcc agcgggctcg
    35401 acccggacac cctcgacccc gcccgggtcg gggtcagcct cggcagcgcg gtggcagcgg
    35461 cgaccagcct ggagcgcgag tatctgctgc tgtcggactc cggccgtgac tgggaggtcg
    35521 acgcggcctg gctgtcccgg cacatgttcg actacctggt gcccagcgtc atgccggccg
    35581 aggtcgcctg ggcggtcggc gccgagggcc cggtcacgat ggtctccacc ggctgcacct
    35641 cgggcctgga ctccgtcggc aacgcggtcc gggcgatcga ggagggcagc gccgacgtga
    35701 tgttcgcggg agccgccgac accccgatca ccccgatcgt cgtcgcctgc ttcgacgcga
    35761 tccgcgccac gacggcgcgc aacgacgacc cggagcacgc ctcgcggccg ttcgacggta
    35821 cgcgggacgg cttcgtgctg gccgaaggag ccgcgatgtt cgtcctggag gactacgaca
    35881 gcgcgctggc ccgcggagcc cgcatccacg ccgagatctc ggggtacgcg acgcgctgca
    35941 acgcgtacca catgacgggc ctgaaggccg acggccgcga gatggccgag accatccggg
    36001 tcgccctcga cgagtcccgc acggacgcga cggacatcga ctacatcaac gcgcacggct
    36061 ccggcacccg gcagaacgac cgccacgaga cagcggcgta caagcgcgcc ctcggcgaac
    36121 acgcccggcg cactccggtc agctcgatca agtcgatggt cggccactcg ctgggcgcga
    36181 tcggctcgct ggagatcgcg gcctgcgtac tcgccctcga acacggcgtg gtgcccccga
    36241 ccgccaacct gcgcaccagc gaccccgagt gcgatctcga ctacgttccg ctggaggcca
    36301 gggagcggaa gctgcggtcc gtactcaccg tgggcagcgg cttcggcggc ttccagagcg
    36361 cgatggtgct gcgcgacgcc gagaccgcgg gggcggccgc atgagcgtcc tcatcaccgg
    36421 agtcggcgtc gtcgcaccca acggcctcgg cctggcgccg tactggtcgg cggtgctgga
    36481 cggccgccac ggcctcggcc cggtcacccg cttcgacgtg agccggtacc cggcgaccct
    36541 cgccggccag atcgacgact tccacgcgcc ggaccacatc ccgggccggt tgctgccgca
    36601 gacggacccc tccacacggc tcgcgctgac cgccgcggac tgggccctcc aggacgcgaa
    36661 ggcggacccg gagtcgctga ccgactacga catgggcgtg gtgaccgcca acgcctgcgg
    36721 tgggttcgac ttcacccacc gggagttccg caagctgtgg tccgagggcc ccaagtcggt
    36781 cagcgtgtac gagtccttcg cctggttcta cgcggtgaac accggccaga tctccatccg
    36841 gcacggtatg cgcggtccga gcagtgccct ggtcgccgag caggccgggg gcctggacgc
    36901 cctgggccac gcccgccgta cgatccgccg cggcacgccg ctggtggtct ccggcggggt
    36961 ggactcggca ctcgacccgt ggggctgggt ctcgcagatc gccagtggcc ggatcagcac
    37021 ggccaccgat ccggaccggg cgtatctgcc cttcgacgag cgggcggccg gctacgttcc
    37081 gggcgagggc ggggccatcc tcgtcctgga ggacagcgcc gcggccgagg cccgcggccg
    37141 gcacgacgcg tacggcgaac tcgccggctg cgcctccacc ttcgaccccg cccccggatc
    37201 cggacggccc gcgggcctgg aacgcgcgat ccggctggcg ctgaacgacg ccgggaccgg
    37261 tcccgaggac gtcgacgtcg tgttcgccga cggcgcgggc gtgcccgagc tggacgccgc
    37321 cgaggcccgg gcgatcggcc gggtgttcgg ccgcgaaggg gtgcccgtca ccgtccccaa
    37381 gacgacgacg ggccgcctct actccggcgg cggcccgctc gacgtggtca ccgccctgat
    37441 gtccctgcgc gaaggggtga tcgcgccgac cgcgggcgtg acgtccgtac cccgggagta
    37501 cggcatcgac ctggtgctcg gcgaaccccg cagcacggcc ccgcgcaccg cactggtcct
    37561 ggccaggggc cgctggggct tcaactcggc ggcggtcctg cgccgtttcg caccgacccc
    37621 gtaacgaccc cgagaactgg agaaagccat ggcaaccctg ctgaccaccg acgatctgcg
    37681 ccgcgccctc gtggagtgcg ccggtgagac ggacgggacg gacctgtccg gcgacttcct
    37741 cgacctccgc ttcgaggaca tcgggtacga ctcgctcgcc ctgatggaga ccgcggcgcg
    37801 actcgagagc cggtacggcg tgtccatacc cgacgacgtc gccggccgcg tcgacacgcc
    37861 gcgagagctg ctcgacctga tcaacggcgc actggccgag gcggcatgag ccggccggga
    37921 gaacaccggg tggtccacac cctgaggacc caggccccgg cgcggcggct ctacgagctg
    37981 gtcgcacgcg tcgaagactg gccggccgtc ttcgaaccca ccgtgcacgt acaggtcctg
    38041 gagcgcggcc cgggcaccga acgcttccgg atctgggcgc gcgtgggcgg ccgggtgaag
    38101 acctggacgt cccgccggac gctggatccc gacaccctga gggtgacgtt ccgccaggag
    38161 ctcacccagc cgcccatcgc ctcgatgggc gggagctggg agttccgggg cgacggcgac
    38221 ggcaccgaag tcgtgctgac ccacgacttc gccgcggtcg acgaagccgc cctgccggga
    38281 ctgcgcgagg cgctggacgc gaacagcggg aaggagctgg ccgcgctggt cgcgctggcg
    38341 gagcgccggc agccgcccga ggagctggtc ttcacgttcg aggacacgct ccgggtgccg
    38401 tccggggacg acgcctacgc cttcatcgag cgcagcgacc tgtggcagga acggctgccg
    38461 cacgtgcgga aggtgacact caccgaggag gcggcgggta ccggccccgc cgagacgcgg
    38521 gacatgaccg tccaggacat gaccatggag acggtgacca ccgacggcgg tacccacacc
    38581 acccgttcga tccggctctg cgtccccgcg aggagcatcg tgtacaagca gctcgtcccg
    38641 cccgccctgc tctccgggca ctgcggcgcc tggaccttcg gcgaggacac ggtcaccgcc
    38701 cgccacaccg tggcgatcga cccggcccgc gtggaagagg tcctgggcaa aggcgcgacc
    38761 gtcgcggacg cccgtaccca tctgcgcgag gtgctcggtg ccaacagccg ggccacgctc
    38821 cgccacgcgg cggccgccgc cgggccggcg tcatgacggt cgaggtccgt gaggtcgccg
    38881 agggtgtcta cgcctacgag caggcccccg gcggctggtg cgtcagcaac gcgggcatcg
    38941 tggtgggcgg cgacggcgcg ctcgtcgtcg acacgctgtc gacgatcccg agggcgcggc
    39001 ggctggcgga gtgggtcgac aagctcgccg cgggccccgg ccgtaccgtg gtcaacaccc
    39061 acttccacgg cgaccacgcc ttcggcaacc aggtcttcgc gccggggacg cggatcatcg
    39121 cgcacgagga catgcggtcc gccatggtga cgaccggcct ggccctcacc gggctctggc
    39181 cgcgggtcga ctggggcgag atcgagctga ggccgccgaa cgtgaccttc cgcgaccggt
    39241 tgaccctgca cgtcggcgag cgacaggtcg aactgatctg cgtcggcccc gcgcacaccg
    39301 atcacgacgt ggtggtctgg ctgcccgagg agcgggtgct gttcgcgggg gacgtcgtca
    39361 tgtcgggcgt cactccgttc gccctcttcg gttcggtggc cggcacgctg gccgcgctcg
    39421 accggctggc ggagctggag cccgaggtgg tcgtcggcgg gcacggcccg gtggcgggac
    39481 ccgaggtgat cgacgccaac cgggactatc tgcgctgggt ccagcgcctc gccgccgatg
    39541 cggtcgaccg ccggctgaca ccgttgcagg ccgcgcgccg ggcggacctc ggcgccttcg
    39601 ccgggctgct ggacgcggag cgcctcgtcg cgaacctgca ccgggcccac gaggagctgc
    39661 tgggcgggca cgtgcgtgac gccatggcga tcttcgcgga gctggtcgcc tacaacggtg
    39721 ggcagctgcc cacctgcctc gcctagggag ttcgaagatg gcagccgacc agggaatgct
    39781 ccgggacgcc atggcccggg tgccggccgg ggtggcgctc gtcaccgccc atgaccgcgg
    39841 gggagtcccg cacggtttca ccgccagttc gttcgtgtcc gtctcgatgg agccgccact
    39901 ggcactggtc tgcctggctc gtacggccaa ctccttcccg gtgttcgaca gttgcggcga
    39961 gttcgcggtg agcgtgctgc gcgaggacca cacggacctg gccatgcgct tcgcgcgcaa
    40021 gtccgcggac aagttcgcgg gcggggagtt cgtccgtacc gcgcggggag cgaccgtgct
    40081 cgacggagcg gtcgcggtcg tcgagtgcac ggtccacgag cgctacccgg cgggcgacca
    40141 catcatcctg ctcggcgagg tccagtccgt gcacgtcgag gagaagggcg taccggcggt
    40201 ctacgtggac cgccggttcg ccgccctgtg ctcggcggcg ggtgcctgcc cgtccgccac
    40261 cgggcggggc gtgcccgcgc atgccggctg aggccggccg ggaaggccgt cagcggcccg
    40321 tggcaccgtc gatcagctcg cggaggatgt cggcgtggcc ggcgtggcgg ccggtctcct
    40381 ccaccatgtg ggtgagggcc cagcggacac tgggcgcggg gcggcccggt cgcggccggg
    40441 ggagcggtgc gccgaggtcg gtgcaggcgt cgagcacgcg gttcgcccgt tcgacggcct
    40501 cccggtagcg ggcgacgacg tcggcgacgc cgtcctggga cgcggcccgg aacgtcgccg
    40561 gccagcttcg cacctcctcc ccgaggaaga ccgcgcgctc gacgtgggtc aggtggttga
    40621 gcagcccgag caggttggtg ccggacgcca ccgccgccgt gcggacctgc ggttcggggg
    40681 cgtcctcgac cttgccggcg atcgaggtcc gcaggtagtc gaggaacccg cgcagggtct
    40741 cggcctcacc gccgccggtt cggggcggcg gggtgtcccg gcggtgggtg cggggggtgg
    40801 tgggcatggt gaccggcctc cggaaggtgt ggggcgggcg ggccgcgggc gcggggcccg
    40861 tcagtccgcg cggcggacga gcaggacgtg gtcgacgacc tcggcggtgc gcccgcccgg
    40921 gccggtcgcg gtccggcgtg gcgcctcggc ccgttcgacc cgccacgtcg ccgggtccag
    40981 ggcgaggtcc gccgcgacct cctgcggggc cgggtggcgc gcgtcggggt cctggtccca
    41041 cgaccacggc gccgtcgagc cgtggtcgac gaccagcagc cgcccgcccg ggcgcagcgc
    41101 gtgcgcggcc ccgcgcagga ccgacgcgcg gtccaggtcg aagggcgtgt ggaggtagtg
    41161 cgcgctgacc aggtcgaacc ggccctcggg gaaggagtcg cgcaggtcgt gccgcacggc
    41221 gtcgaccagg tcgccgaggc cgtgggtccg tgcgtgcccc gcgagccgct cggccgcgac
    41281 cccggagatg tccacggccg tgacccgcca gccccgccgg gcaagccaca gcgcgtcgcc
    41341 gccgctgccg caccccaggt ccagggcgtc gccgggcggc aggccggtga ccgtctcgac
    41401 caggcggacg ttcgggcggg gcgcgtcggg cgccgggcgg gcggcgtaca cgccgtccca
    41461 gaacgtgacc gcgtcggtgg tgctcatcgg aactccttca gtcgtttcgg ccggcggcgg
    41521 gcgacgagtc gggcaacgcg ccgcgagccg tcgatgcgac cagtctcgac accctccgcc
    41581 cgaaccggca cgaaaacttg cggttgtggc aaggtggccc gatggacgcc gcaacggacg
    41641 acgtgctcga cgccgtgggc ccacgcctgc gcacgctgcg ccgcgagcgc ggcatcaccc
    41701 tcgcccacct ctcggcggcg accggggtgt cggagagcac cctgtcccgg ctggagagcg
    41761 ggcagcgccg tgcgaccctg gagctgctgc tgccgctcgc ccggatctac gacgtccccc
    41821 tggacgacct cgtcggcgcc ccgcgcacgg gcgacccccg catccacctg aagccggtca
    41881 ggcgcttcgg gatggtcttc gtgccgctgt cccggcggcc gggcggcacc caggccttca
    41941 aaatgatcat cccgagccgt ccggcgccgc tcgaaccgac cccgcagacc cacgaggggt
    42001 ccgagtggct gtacgtgctc agcggccgtc tgcggttgct ggtcggcgag cgcgacctga
    42061 cgctgtcgcc cggtgaggcg gccgagttcg acacgtcgct gccgcactgg ctgggcagcg
    42121 ccgacggcgg cgcggtcgaa ctcctcgtcc tgttcgggct gcagggcgtg cgggcccatg
    42181 tgcacagcgg ctgagagctt cctgcccgac ggcgtcgccg agcgggtcgg ctgggcgcgc
    42241 gaggcggccg aggcgacgcc ggaccggtcg gcggagggcc cgcgcgacag tcctgagggg
    42301 gcgtcgcgtc cgcgtgttgc ccggcagccc gcccggtccg tcgcccggcg tcacatccgt
    42361 gcgtcgcccg gcagcccgcc cggtccgtca tccggcgtca cgcccggtcc gtcgcccggc
    42421 gtcacgcccg gtccgtcatc cggcgtcacg cccggtccgt cacccggcgg caggcctcca
    42481 cgtacccgcg caccagtgcc cgcccctcgt cctcgcggcg ccgggccagg gcgtagcggc
    42541 tgggggacag gccgcggacc gggcgggtga ccaccccgcc cagggtgatc agcggggcgt
    42601 tgcccgtggc caccaggcag atgccgagcc cggcgaccag ggcctcgtac gtctcctccg
    42661 tgccggagat ctcggcgccg acgcgcggcg gacgggcggc ggggccgtcg agtgcgcgcc
    42721 gttcgtccag cgccagccag aagtcgcgca ggacgcccgc ctccgggggc agggcgagga
    42781 acggctcgcc ggccaggtcg gcgaagtcga tctcctcgcg ggcggcgagg gggtggctgt
    42841 cggggagggc gaccaggcgg ggctcctcgg cgaccaccgt ccaggcgtag cggtcggcgt
    42901 cgggcagcgg cagccagacg tacgcgacgt cggccgtgcc gtcggccagg cccgcggtcg
    42961 ggtcctccca gctcatctgc cgcagctgca ggaccgcctc cgggtgggcc gcggtgaagc
    43021 gggagcggat cgccgggagc agcccgccgc ggccggggct ggtgctcatg ccgacgacga
    43081 gggtgtcgcg ccgggccgca cgggccgcct ccaccgccgc cgcgccctcg gtccagtcgg
    43141 ccagcatccg ccgggcgtgc ggcagcaggg ccgtgcccgc ctcggtgagg gtcacgcccc
    43201 gggggccgcg gtggaacagc tcggcgccca actgccgttc cagggcccgg atctgcttgc
    43261 tcagcgcggg ctgtgacacg tacaggagtt cggccgcccg cgtgaagtgc agctcctcgg
    43321 ccaccgtcgc gaagtagcgc agctcccgca catgtacgtc cgtcgtcatg cccatgggtt
    43381 atcaccgcgg gtcttggacc ggcaaccggc ttgtggacga gggtggttgg cgtcggaaca
    43441 aggcgacaga ggaaaccgag ggagtcggga tgaacaaggt gtggctgatc accggggcga
    43501 gcagcggctt cgggcgggcg atcgccgagg cggccctggc cgacggcgac gtcgtggtcg
    43561 gcgcggctcg gcgccccgag gcgctggacg acctcgtggc cgcgcacccg gaccagatgg
    43621 aggcgctgcg cctggacgtc gccgacacgg ccgccgccgg ggacgccgta cgggacgtgg
    43681 tggcgcggca cggcagggtg gacgtattgg tcaacaacgc gggccgcaca cacgtcggtg
    43741 ccctcgagga gaccggcgag gacgaactgc gggcgctgtt cgacgtgcac gtcttcggcc
    43801 cggccgcgct gacgcgcgcg gtactgccgt ccatgcggga gcggcgttcg ggcgcgatcg
    43861 tgcagatgag cagcatgggc gggcagatgt ccttcgcggg cttctccgcg tacagcggca
    43921 cgaagttcgc cctggagggc atgtccgagg ggctcgcgga cgaggtccgg gacttcggca
    43981 tcaaggtgct gatcgtcgag ccgggctcct tccgcaccgg cctgttcgag gccgggaacg
    44041 ccgggatcag cgccgacagc ggcgtgtacg ccaaggtcgg cgagacccgc gggatgatcg
    44101 ccgcgggcga cggcagccag cccggcgacc ccgccagggc ggccgcggtc atccgcgcgg
    44161 ccctcgcggc cgagcacact ccgctgcgcc tgccgctggg cgacgacggc gtcaccgcgg
    44221 tcctcggcca cctcgaccgg gtccgcgagg aggtcgagac ctgggagaag cagacccggg
    44281 ccacggcgtt cgacgactga ggggcagcgg ggtgtcggtt cggcaccttc ggtgcccgca
    44341 cccgaccgca cccgactgtg cccgactgca cccgaccgtg cccgatcgtg cccgtgccca
    44401 tgcccatgcc catgcccatg cccatgccca tgcccatgcc cgtgcccgtg cccgcgtccg
    44461 tgccgaacca ggagtccgcc gtgctctcgt ccctgaaggc cgtcaacctg ctggtgatgt
    44521 tcctgctgga actcgcggtg tacacggcgg tcgtgctctg gggggtcgcc gtcggcggca
    44581 catggccggt cgaggtggcc ctgggggtgg gcgcgccggt cgtgatgatg gcggcgtggg
    44641 cgctgttcgg gtcgccgcgc gcccgccgtc cggcgcgcgg ggccgggcgg ttcgtcctgg
    44701 aggtgctctg gttcggtgcc ggtgcggccg ccctggccgc ctccgggaga ccgtggtggg
    44761 cggccgccct cgccggggtc tgcctggtca acgcggtgct cagacggttg tggaagcagt
    44821 gacgcccggc gcgcccgcga cccgcgcacc gccccccgcg cggaccgcgc ttacgatgcg
    44881 cgaggccgca cccgtcgccg caccaccctc tcgaacagga gcacggtact cgtgtcgata
    44941 ccgccaccgc cggggcccca agggcagtac ccccagggtc cgtacgctcc gcagtggggg
    45001 caccccctcg cgccgtaccc ccggccggct cccgtgagcg ggctcgccgt cgccgcgttc
    45061 gtcctcggcg tcctgtgctt cctgccggcg gtcggactgg tcctcgggct ggtcgcgctg
    45121 gcccggatcc gcaggcgggg cgaacgcggc aaggggttcg cggtggccgg ctgcgtgctg
    45181 tcctccgtgg ggctggccct gtggacgctg acgctgtcga cgggcgccgc gggcgacttc
    45241 tgggacggct tccgggacgc cgcgcgcggc gggggcaccg cctactccct ggagaagggc
    45301 cagtgcttca ccacccccag cggctccctc caaggggtga cgtacgacgt cgacgaggtg
    45361 ccctgcgcgc gggagcacga cggcgaggtc ttcgcctcct tcgacctgcc ggacggttcc
    45421 tacccgggcg acggggagat cacgcgggcc gccgacgacc ggtgctacgc cctccaggac
    45481 gcctacgcga tggaccggtg ggcactgccg accgacgtcg acgtgtacta cctgaccccg
    45541 accgccgcga gctggcggac cggcgaccgc gagatcacct gcctgttcgg caacacggac
    45601 gagcggggca cgctgaccgg ctcgctgcgc aacgacggcg cgcggttcga cgcggaccag
    45661 cacacctacc tgctcgcgga gggctacctg aaccgggcca tggacgaggt gcccgcggcg
    45721 gaggcggtcg aggacgacct cgcgggctac cggacctggg ccgggcaggt ctcggaggcg
    45781 ctcaggggcg aggtcgcgat gctggacggg cacgagtggc ccgccggcgc cgagcgcccg
    45841 gtcgccgcgc tgaccgacga cctgcggtcg gcgcaggagg agtggggcct ggcggctaag
    45901 gccgccgacc tcgacgcgta ctacgagcac tacggcaagg gctacgacct cgtcgtcgcc
    45961 gacagcacgg tcaccgcacg caaggctctg ggcctggcca ccacgccgcc ggactacgag
    46021 ggcggcgagg gcgggggaga cgaccccggc gtggaggtgt gacagcggcc atagcgggga
    46081 gaaagtgcct gcgtaaagcc ctcgggcggc gcaagtcatc acatcgagtg attctttggc
    46141 ctttgcttgc ctgggccaac ctacggttgc cacgctgttg ctgtctgtac aacctgatgg
    46201 gagcggccag tgacattcgg tgagcagccg gcgtatctgc gtgtcgcggg tgatctccgc
    46261 aagaagatcg ccgacggcct gctgccgccc catacccgcc tcccgtccca ggcgcggatc
    46321 cgcgaggagt acggggtctc ggacaccgtc gccctggagg cccgcaaggt gctgatggcc
    46381 gagggcctgg tcgagggccg ctccggttcc ggcacctacg tgcgcgagcg gcccgtcccg
    46441 cggcgcgtcg cccgctccgg ataccggccg gccggcgggg ccacgccctt ccgccaggag
    46501 caggccgacg gggacgcgcg cggcacctgg gagtcgcgca gcgagcaggc cgaggcgagc
    46561 ggtgccgtgg ccgagcggct cgggatcaag cccggtgacc gggtgatgtg cacgcggtac
    46621 gtcttccggg aggccggtga ggccgtcatg ctctccacct cctgggagcc gctggacctg
    46681 accggccgca ccccggtgat gctgcccgag gaagggccgc tcggcgggat gggtgtcgtg
    46741 gagcggatgg ccgccatcga cgtcgtcgtc gacaacgtca ccgaggaggt cggcgcccgt
    46801 cccggcctcg ccgaggagtt gctcgccctg ggcggcgttc cgggacacgt ggtgctggtc
    46861 gtccagcgca cgttctacgc ctcggggcgt gccgtggaga ccgccgacgt ggtcgtcccg
    46921 gccgaccgct accgggtggc gtaccacctg cccgtcaggt agcccgtcgg gcagcccctc
    46981 aagcagggcc gtggccggga gtgttcgggg gctctgccgc gatgcggggc ggcggggtga
    47041 gacggcgggg cgggacggcg gtgtgagatg gcgcacgcca gtcgtgcgcc tcccgtgtcc
    47101 cgttcccccg ctcacgcatc cgccggggcc cgcggcgtcg ttcgcccggc gccggaatcc
    47161 ggtcgttccc ccaggtcgct tccccggtgc ccggcacgcc tgtgaccgga ggcatcggtg
    47221 tgcggagacg gcgcgttccg cgtcgtgcgc cccctgcgtt ctggctggtt gcgtacctct
    47281 ttgtgcaaag ccgtgttcgc tccgtgaagg ttgggcgtag gctcgggcat atgcggattg
    47341 cggtttcctt ggcgggcggg gcgcggcggg tgccgcgggc ggcgggaacg ggaagcggag
    47401 gggcgcgatg aacgacagca cggtcactct tccctggctg gtcttccggc aggacgacaa
    47461 cggcaatcgc tatcgcgtgg gcaggtacgc cacccgggcg gaggcccagg agatcgcgga
    47521 caccctcgac ggtcgcggcc acaagcagct ctactgggtc gagaaactcg ccgcgcccgg
    47581 cgcgggcgcg gcggactgac ccaccgcgga ccggctcatc gcggaccggc tcaccgcgga
    47641 cccgcccggc cgggcaggcc gtaggctccg gcgcatgacg gaacggatcg tggtgggcgc
    47701 cgccctgctc gacggcgggc gcctgctcgc cgcgcgccgc agcgcacccg ccgaactggc
    47761 cggacggtgg gagctgcccg gcggcaaggt cgagccgggc gagacgcccg aggcggcgct
    47821 cgtacgcgaa ctgcgcgagg aactcggggt ggcggccgag gccggtgggc gcgtccccgg
    47881 gcagtggccc ctgcgggccc ccttcgtcct ccaggtgtgg accgcccgcc tgcgccccgg
    47941 ctccgcggcc cccgcgcccc tggaggacca cgacgagctg cgctggctga cccccggcca
    48001 gatctgggac gtgccctggc tcgaccagga cgtaccggcc gtcgagcggg tgctcgcaca
    48061 cctgggactc gaggcgggca ccgggaggaa cggtaccggg cccggataaa gggtatgtgc
    48121 ccattaaccc catgaaaacg ggcatcgatg gggtcgtcgg ccggggaagt gatcggcgtg
    48181 aaggacggcg agggcgactg tgccgagtgg gtctttcccg cggcgccgga cgccgtgcgc
    48241 accgcccgct ccctggtccg ccgcaccctg ggcgagtggc ggctcgacag cgtcggggac
    48301 atcgccgccc tgctggtcag cgagctggtc accaacgccc tgcggcacgc gaccggcccc
    48361 atcggcgtcc gcctggtgcg cagccccgcc ccggccgccc cggccgccgg aggcgccgga
    48421 ggcgacgggg ccgacggtgt cctgctggtg gaggtctccg acccgctgcc ggacccgccc
    48481 cgcgagcgcg tcgcccgtcc cgacgacgag gacggccggg gtctgcagtt ggtggcctcc
    48541 gccgcacggc gctggggcac ccgtcccggg gaggcgggca agaccgtgtg gttcgaactc
    48601 gccctgccgc gctagtgcga cggtcccgtg acgcaccgtc gccggcgcat cggccgacgc
    48661 tcggaatgcc ccggtatcgc ccctggtccg ggtcgccaac cggttcaggc cagtggcagt
    48721 tgtggaactg cgtgattcga tgccgtgtcc gctggttaga agactggaag tgttgtcgcg
    48781 gtccggaccg aaaaccatcg ggaccgtgct gtgatcgtga acaccgtgtc gtgcggcgcc
    48841 gtagtgctgg atactgcggg cagccgcctc cggtgaccgg tgccggatgc ggtgagctgg
    48901 aggggacggt tcgcgtgagc gagataccag cgagggccaa ggagcccacg gagtccacgg
    48961 agtccggggg cccgtcggca gacgcgccac tcggtgacgc ggtgtggcag agcagcccgc
    49021 ccggctccat ctacgactac atcaaggtcg cctccttctc catcggcccc gacgggctcg
    49081 tcgaccagtg gagcctgcgt gcggagcaac tgctcggcat ccgggccgag gacgccgtgg
    49141 gcagcgatcc catcgaggcc ttcatcgacc ccgacctgcg ggagcgcggc cagcgcaaga
    49201 tgaccgagat cctcgacggc cgggaatgga ccggagtggt ccccttccgg gcaccggacg
    49261 aggccgaggg gacggcgcgg cacgcgagcg gccggcccgc cgacggcccg cccaccggcg
    49321 gccggcccgg acagcgcgga ctcgccgagg tgtacgtcat gccgacgcgc acggaggacg
    49381 gggagaaggc cgccgtctgc atcgtcgtcg acgtccgcgt gctgcgcagc atcgagacgg
    49441 atctcgccgc gtcgcaggcc attttcggcc agtctccgtt cgggttcctg ctcatcgacc
    49501 ccgacctgac ggtgcgccgc gccaaccagc ggttcgcctc catcttcggc ggcacccccg
    49561 acgaccaccg cggcaagggc gtccacgact acctgccgcg cgccgaggcc gaccgggtct
    49621 gcgcgaccct gcgccgggtc ctggagaccg gcgactccat cacggacatg cacgtcacgg
    49681 gcttcgtgcc gggctcggag gagcgccgcc actggtccgt caacctctac cgcgtgcaca
    49741 gcggttccgg ccggcccatc ggcgtcgcct ggctcggcac cgacatcacc gcccgccgcc
    49801 aggccgcccg cgaggccgcc aacgcccggc gcaacctcgc cctcctcaac gaggccggcg
    49861 cccgcatcgg caactccctc gacctggaga ccaccgcccg cgaactcctc gacgtcgtcg
    49921 tccccggctt ctgcgacctg gccaccgtcg acctctacca gggcctgctg gtcggcgacg
    49981 agaccccgcc gggactcgcc gacggcagcg cggaactgcg ccgcgtcgcc ttctccagtg
    50041 ccgtctccga cgccccgttc ctgggcaccg gcgagcgggt caagctcggc gccgtccacc
    50101 actacccgtt caactcgccc tgcgccgacg ccctgcgcac cgcccggccg cgcagcgtcc
    50161 ccgccgagga cggcggtctg gtgcagtcca cgctcgccgt gccgatggtc gcccacgaca
    50221 cggtcgtcgg actggtccag ttcgcccgta ccaagggcag cgagccgttc ggcgaccgcg
    50281 accgcgacct cgccgtggaa ctggccgcgc gcgccgccgt ctgcatcgac aacgcccggc
    50341 tctaccggcg cgagcacgaa cgcgcgctga tactgcaacg ctccctgctc ccgcccggcg
    50401 acccggaggc ctccggactc gacatcgcct gccgctacct gcccggcgag gcggccaccg
    50461 gccgggccag cgaggtcggc ggcgactggt tcgacgtgat cgaactcccc gggcaccgca
    50521 ccgcgctggt cgtcggcgac gtcatgggcc gcggtctgcg cgccgccgtc gcgatgggcg
    50581 aactgcgcac cgccgtacgc accctggccc agctcgacat cgaaccggcc gaggtgctct
    50641 cccagctgga cgagatcgcg cgcggcctcg gcgctcccgg gggcgtccag caggccaccc
    50701 gggccgcccg ccgcccccgc gaggccgacc tgtccgaggt ctacctggca acctgcgtgt
    50761 acgccgtcta cgactcggtg accaggcgct gcaccttcgc caacgcgggc cacctgccgc
    50821 ccgtcctggt cgagcccggc gagtccgcgc tgatgctgga cgtgccgccc ggtctgccgc
    50881 tcggcgtcgg cggggagccc ttcgaggagg tggaggtcga actgcccgag ggcgccctgc
    50941 tcgccctcta caccgacggc ctggtcgaga gccgcgacca ccccctcgac gagggcctcc
    51001 aggccttcgt gggcgccctc acggacccca cccagcccct ggaggacgtc tgcgaccagg
    51061 tcctcaacac cctcgacagc caccacggcg aggacgacat cgcgctgctg atggcccgcg
    51121 tccagggcct gcccgccgac agcgtcggcg actggaccct gccgcgcgag ccgcgcagcg
    51181 tcggccgggc ccgcgagtac gcccgcgccc agctgctggc ctgggacatg gagccgctgg
    51241 tcgacaccac cgaactgctc gtcagcgagc tggtcaccaa cgcgctcagg tacggcgagg
    51301 gcgagatcag gctccgcctc ctgctcgacc gcaccctggt gtgcgaggtg tgggactccg
    51361 gcctggtcca gccgcgccgg cgccgcgccc gggacaccga cgagggcggc cgcggtctgc
    51421 aactggtcgg cctgctcagc gcggcctggg gctctcgccg tacgccgcgc ggcaagacgg
    51481 tctggttcga actgcccctg ccgggcgccg acacccagct cacggacccc gcggaggcct
    51541 tgctgagcct gttctgaccc ggcccggcgt cgtacgggtc cgggcccgcc ggatacggcg
    51601 cacccggccg catccggcca gcagcagggc tgccccggcc gtgaccaggg gcggcaccag
    51661 atcgacggag atcaccgccg cgcacccctc accgcaaccg gaacaccggt tcgagtcgtc
    51721 cccgctggca ccacgctcgg agcgtaagcg cggcgaccgg tcaccgcgac cggagacgga
    51781 ccacagggag gggacaccgt ggcggacacg gaaccgggaa acaccgaacc gagaagcacc
    51841 gaaccgggaa acaccgaact gagaagcacc gaaccgggaa gcatcgaacc gggaagcacc
    51901 gaaccggaag ccgccgacgg cgaggacggg ccaccggggc cacccgcatc cgacgacgaa
    51961 agcggcacag gcggtgcggg tgggaaccgg gacgccgaag gcgaagccga ggcgacccga
    52021 cgaacacgcc gccgtacccg catccgccgg acggccgtag ccgtcctcct ggtcctgctc
    52081 gtccccctcc tcaccgccga gacagccctc cgcgtcaact acatgggcga ccccgccgac
    52141 ggcactcaca ccagaaaccg cgacgcgatg tggctcggcc acgcgtgggt cgacggccgt
    52201 aaggacgacg cggacctcgc cgccttcgcc cgccgcgtca aggcgaccgg catccgcgac
    52261 ctgtacgtcc acaccggccc gatggagcac gacggcacgc tgccgaagtc cctctacccc
    52321 agggcccgct ggctggtggg cgccgtgcac cgcgagctgc ccggcgtccg cgtccaggcc
    52381 ttcctcggcg acgtcctcgc caccgagagc cccgacggca tgcgcctgga gaagcccgcc
    52441 acccgcgccg ccgtcgtcgg ctcggcccgc caggtcctgg acgtcggtta cgacggagtc
    52501 cacctggacc tggaaccgct gcactcgggc gacggcgact acctctcgct cctggacgac
    52561 gtccgcgccg tcacccgcgc ccgtgacgcg cagctctccg tcgccgccca ccagatcgac
    52621 ccgctgcccg gcttccactc cttctggggc acggtcgccg gacaccccaa gtggtggtcg
    52681 caggagttct tcggccaggt cgcccgccgc gtcgaccaga tcgccgtcat gtcgtacgac
    52741 acgatgcagc cgctggagag cctgtacggc ggctacgtcg cccagcagac ctcgctggcc
    52801 ctggaggtca ccccgccgac gacccacctc ctgatgggcc tgcccttcta ccacgagaac
    52861 cgcttcggcc actggaacca cgcggagacc gtcgccgccg ccgtccgcgg cgtccgcctc
    52921 ggtttgtccc gcacggacgc cgaccgggag aggttcggcg tcgccgcgta catcgacttc
    52981 gcggcgacgg agcaggactg ggcgtcgtac cgggacggct gggtgcgcta gggggtgtcc
    53041 cgggaccggc ggccgatctt cgcgcccagc cagaccagcg ggtcgtactt gcggtcgacg
    53101 gcccgctcct tcaacgggat cagcgcgttg tccgtgatcc tgatgccctc cgggcacacc
    53161 tccgtgcagc acttggtgat gttgcagaag ccgaggccgt gctcgtcctg ggccgtgcgc
    53221 gagcggtcca ggccggtgtc accggcggcg tccagcgggt gcatgtccaa ctcggcgacg
    53281 cgcatgagga agcgcgggcc cgcgaaggcg ggtttgttct cctcgtggtc ccgcacgaca
    53341 tggcaggtgt cctggcacag gaagcactcg atgcacttgc ggaactcctg cgagcggtcc
    53401 acgtcctcct gcatcatccg gtactcgccc ggcccgaggt cggcgggcgg cacgaaggcc
    53461 gggacctcgc gggccttggt gtagttgaag ccgacgtccg tcaccaggtc ccggatcacc
    53521 gggaaggcgc gcagcggcgt gacggtgatc gtctcctcgc gggtgaagac ggacatgcgg
    53581 gtcatgcaca gcagccgcgg ccgcccgttg atctcggccg agcacgaacc gcacttgccc
    53641 gccttgcagt tccagcgcac cgcgaggtcg ggggcctggg tggcctggag gcggtggatg
    53701 atgtcgagga ccacctcgcc gtcgttcacc tcgaccgtga agtcctcgag gccaccgccc
    53761 gccacgtcac cgcgccacac cttgaagcgg gcctcgtaac cgctcattcg gaccggccct
    53821 ccagttcctc gtcggcgagg tacttcacca gctcctcctt gtcgaagagg gcgagcaggt
    53881 cgggccggat gggctcggtg gtctgccgct ccagggcgat ccggccgcgc tccgggtccg
    53941 tcgccgccgc ctcgcccgct gcctcgcccg ccgggtcggc cagcgagcag agcaggttgg
    54001 ccgggcgcca gcgccggtcc atcgacggat ggtcctcacg ggtgtgcccg ccgcgcgact
    54061 cggtgcgctc cagcgcggcc cgcgccacgc attcgctgac cagcagcatg ttgcgcaggt
    54121 ccagggcgag gtgccagccc gggttgaact gccggtgccc ctcgaccccg gcccggcggg
    54181 cgcgcacccg cagctccgcc agcttctcca gggcctgctt catctccgcc tcgcggcgga
    54241 tgatccccac caggtcgttc atggtctgct ggagttcctg gtggagggtg tacgggttct
    54301 ccggcgggcc cgcgccgggc tcctgcgcct cggcggagaa cggccgcagg gcctccgcgg
    54361 cggccgcgtc gacctgggcg tcgtcgaccc gggcgcgggt gccctcctcc gtccgccccg
    54421 ccgcgtactc ggccgcgtac cggcccgccc gccgcccgaa caccagcagg tcggacagcg
    54481 agttgccgcc cagccggttg gagccgtgca tgccgccggc cacctcaccg gccgcgaaca
    54541 gtcccggcac cccgcgggcg gcggcggtgt cggagtcgac ggcgatgccg cccatcacgt
    54601 agtggcaggt cggcccgacc tccatcgcct ccgccgtgat gtccacgtcc gccagctcct
    54661 tgaactggtg gtacatcgag ggcagccggc gcctgatcac ttcggcgggc atccgggtcg
    54721 acacgtcgag gaagacgccg ccgtgcggtg agccccggcc ctccttcacc tcggcgttga
    54781 tcgcgcgggc gacctcgtcg cgggggagga gttcgggcgg gcgccggttg tggtccgggt
    54841 cgtcgtacca gcggtcgccc tcggcctccg actcggcgta cttctccttg aagacgtccg
    54901 ggacgtagtc gaacatgaac cgcctgccct cggagttcct cagcaccccg ccgtcgccgc
    54961 gcaccgactc ggtgacgagg atgcccttca ccgagggcgg ccagaccatg cccgtcgggt
    55021 ggaactgcac gaactccatg ttgagcagcg gcgccccggc cagcagcgcc agggcgtggc
    55081 cgtcgccggt gtactcccac gagttcgacg tcaccttgaa cgacttgccg atgccgcccg
    55141 tcgcgatcac caccgagggc gcctggagga cgaagaagcg gccgctctcg cgctcgtagc
    55201 cgaagacccc cgagaccttc cggtcctcct ggagcaggcg ggtgaccgtg cactcctgga
    55261 agaccttcag ccgggactcg tggtccccgg tctcgcggaa gtcctcctgc tggagcgaga
    55321 cgatcttctg ctggagggtg cggatcagct ccaggcccgt gcggtcgccg acgtgggcga
    55381 ggcgcgggta ctcgtggccg ccgaagttgc gctgcgagat ccggccgtcc ttcgtccggt
    55441 cgaacagcgc gccccaggtc tccagctccc acacccgctg cggggcctcc tgggcgtgca
    55501 gctcggccat ccgccactgg ttgaggaact tgccgccgcg catggtgtcg cggaagtgga
    55561 cctgccagtt gtccccggag ttgacgttgc ccatggaggc ggcgatgccg ccctcggcca
    55621 tcaccgtgtg cgccttgccg aacagcgact tgcagatcac ggccgtacgg gcgccccgct
    55681 cgcgggcctc gacggcggcg cgcagcccgg caccgcccgc gcccaccacg acgacgtccc
    55741 attcctgccg gtcgaccacg gacatcagaa agcctcactc gtcagaagaa gcgcggatcg
    55801 tcgaagacac cggacgcgac caggtacacg tagaagtcgg cgagcgccac gctcaccagg
    55861 gacgcccagg ccagctgcat gtgccgggcg ttgagccggc cgaccagctg ccacatccgg
    55921 tagcgcacgg gatgccgcga gaagtgcttg agcttgcccc cgacgatgtg ccggcaggag
    55981 tggcaggaca gggtgtacgc ccagatcagc gcgatgttgg cgaggaagac cagggtgccg
    56041 agccccatgt ggccccaggc gtagtgctcg tcgcggaagg cgagcacggt gtcgtagctg
    56101 aggatgcccg cgaccaggag cgccgcgtag aagaagtacc ggtggacgtt ctgcaggatc
    56161 agcgggaagc gggtctcgcc ggtgtacttg cggtgcggct cggccaccgc gcaggccggc
    56221 ggggaggccc agaagccccg gtagtaggcc ttgcggtagt agtagcaggt caggcggaag
    56281 ccgagcggga agatcaggat gatgatcgcg ggggagatgc cccaccaggt gccgaagagc
    56341 tcccagttgg gccccgagcg catcggctcg cagttctccg ccagacacgg ggagtagaag
    56401 ggcgagacgt acggggccgc gtagtagtcg gcgttcgcga aggcccgcca ggtcgagtag
    56461 acgacgaagg ccagcaggcc cgcggcggtg gcggccggtg ccagccacca gcggtcggtg
    56521 cgcaggtgcc gggcgcggat ggcggcacgc gtcggggtgt ggacgccacc gcccggggga
    56581 cggtcttcgg tggctggcgg ttcggtacca gtggccactg ggcggctccg gtcgggtcgg
    56641 gtcgggttga gggcctttct cgagtccccg gagcaggccc tagggggcgc gccggtcgcg
    56701 ggcgccgaga ccctcgtcgt ccgagtccgt ccacagggag ccgtcgtacg gcgtgtcggg
    56761 gatcgggacg aggtccggac gcctgggcgc ctgaggcgcg gcagtcgccg cccgcagcag
    56821 cgcgacgctc tcgcgcaggt ggtcggcgtc ggtgcggacc cggcggactt ccaggtcgcc
    56881 gctgcccagc tgctgttcca gccgggtcac cgtccgggac agttcgtcca ggctgcgctg
    56941 taccgatgac agatcgtcgt gcacggacaa gacgtgacct cgcttccgtc ggacacggca
    57001 gtgggccgcc ggccttgggg ggctacgttc atgcgcctga gagtgtcgcg cgtcacacca
    57061 gtcgctggga agggatgtgc agcgattggc cggggcgcgt cggtgcaccg cgggcggcat
    57121 tgcgccgcac gggtgacctt acgcaccgtt gtcgccgtgt ctccgagcgt ggcggaaccg
    57181 tttccccttc agtggccgca tccccgtccg gatacaaatg atcaacttga ataccgcaca
    57241 tacggcaaat gcggcacaac gcagcgaacg cggccttccg gaggtagcag agatgtccca
    57301 cgtcggcgtc ggaccgcgcg cggtcatgcg tgcggtcgcc ttcctcacca cgggcgtcct
    57361 cgcggtcccc gcgctggccg gctgcacctc cgaggacccg gcgggcaagc cgctggccga
    57421 acaggacgtc gccgccgcgg cccgcgccag gatctccgac ggcggcaccc tgcgctgggc
    57481 cgtggactcc gtaccggaca cgctgaacgc cttccagtcg gacgccgacg ccacgacgac
    57541 ccgcgtcgcg caggccgtgc tgccctcgat gtaccggatg gacgagaccg gcagccccgt
    57601 gcgcaacccc gactacctgg agtcggccga ggtcgtcgac accgagccca agcaggtcgt
    57661 cgtctacaag ctgaaccagc aggccgtctg gagcgacggc cgggagatcg gcgccgcgga
    57721 cttcgccgcc cagtggcgcg ccctgtccgg caaggacagc gcctactgga ccgcccgcaa
    57781 cgcggggtac gaccgcatcg agaaggtcga gcgcggtgcg aacgacctgg aggtcaaggt
    57841 caccttcagc cggccctacg ccgactggaa ggccctgttc acgcccctgt acccgaagga
    57901 cgtcacgggc accccggacg ccttcaacga cggcgcgcgg cgggccctca aggtcagcgc
    57961 cgggcccttc gcggtcaaga aggtcgacac caagggcgac caggtggtcc tcaccggcaa
    58021 tccccgctgg tggggcgagc cggcgaagct ggacgagatc gtgctgcgcg ccgtcccccg
    58081 cgacgagcgg gtctccgaac tggtcgccgg caagctcgac ctcgccgaga tcgacccgga
    58141 gaccgccgac gaggtcaccc tggccgccgg tccccgggac cccgccaccg gcaccccgct
    58201 catgggaccc gggggcaccc cggccgcggg cccgcagggc aggtctgccg ccgaggcgct
    58261 gcgctcctgg gccatcgcca acggctccga cgaggaggcc gccgaggagg aggtcctcgc
    58321 ccgcgaggag cgcggcgagg ccgaggcgaa ggcccggcgc cggcagcagg ccctgagcgg
    58381 cttcgagctc cgcaagtccc tggagcccgc ctacacccag ctcgccctca acggcgccga
    58441 aggccccctc gccgacgaac gcgtccgcag ggccgtggcc cgcgccctgg accgcgagga
    58501 gctggccgag gcggtgctca agccgctcgg tctgcccgcc gagcctgtgg gcagccatct
    58561 cgcgctctcc ggccagcccg cctacgccga cggcagcggc gccctcggcg agcagaacgc
    58621 caaggaggcc cgagccctgc tcgcggacgc cggatgggtt cccggcggcc cggtgaagaa
    58681 gaaggacggc gaggaggcgg ccggtgccga gaaggacgag aacaaggacg aggacaagaa
    58741 ggacgaggag aagtccgagg gcggcgacga cggcacgtac atcgtcggcg aggacgacaa
    58801 gaacaaggac ggcaagaaca aggacggcaa gaacgacgac ggcaagaacg acgacggcgg
    58861 gaacgacgac ggcgggaacg acgacgccgg cgacgccaag gacggcgccg accgggagag
    58921 cggcgagaag cacagcagcg gcaagaacac cgcgcagggc ggcgcacccg gcgcctacgc
    58981 ccccaagggc accgcggccc cggccggcgc ggcggcggcc ccgctcgcca aggacggcaa
    59041 ggaactcacc ctccgcttcg tgctcccctc cggtcccggc tccggcaccc tgcgcaccgt
    59101 ggccgaccgc atcacggaca tgctgaagga gatcggcatc ggcaccagga tcaccaaggt
    59161 gccggacgag agctacttca aggaccacat cgccgccggc gagtacgacc tggcgctcta
    59221 ctcctggccc gcctccgcgt tccccgccac cgacgcccgt cccatctacg ccaagcccgt
    59281 cccggccgcc gacggttccc tgaacgtcgc ccagaactac acccgggtcg gcaccgacca
    59341 ggtcgaccag ctcttcgacc gggccctggc caccctggac cagaaggagt cccgggacct
    59401 gctgcgcaag gccgactcgc ggatctgggc ggcggccggc tccgttcccc tctaccagcg
    59461 cccccagctg acggcggccc gcaagaacct cgccaacgcc ggcgccttcg ggttcgggac
    59521 accggtctac gaggacatgg gcttcctcaa gaagggtgcc cagggctccc ggcccaccgc
    59581 cccggcctcg ccctccccct cgtcctgaac cctcccggca agccgcagcc tccggggccc
    59641 cgtaccattg ggtgaggccg tggcatgtac cgcccggcag gcccgcgtga cacggacgta
    59701 cgcgagggcc gtccacacac cctccgggag tacgcctcat atggccacgc gccacgacat
    59761 ccgcaacgtc gccatcgtcg cccacgtcga ccacggcaag accaccatcg tcgacggaat
    59821 gctgaagcag gccggcgcct tcgccgcgca ccagctcgaa ggcgtcgacg accgcatgat
    59881 ggactcgaac gacctggagc gtgagaaggg catcacgatc ctcgccaaga acacggcggt
    59941 gaagtaccac ccgaaggatg gcggcgacgt catcaccatc aacatcatcg acacccccgg
    60001 ccacgccgac ttcggcggcg aggtcgagcg cggtctgtcg atggtcgacg gtgtcgtgct
    60061 gctcgtggac gcctccgagg gtccgctgcc gcagacccgg ttcgtgctgc gcaaggcgct
    60121 cagccagcgg ctgccgatca tcctgtgcat caacaagacg gaccggccgg acgcccgcat
    60181 cgacgaggtc gtcaacgaga cctacgacct cttcctcgac ctggacgccg acgaggagca
    60241 gatcgagttc ccgatcgtct acgcctgcgg ccgggacggc gtcgcctccc tcaccaagcc
    60301 cgaggacggc acggtcccct ccgactccac cagcctggag ccgttcttct cgacgatcct
    60361 ggaccacatc ccggcgccga cctacgacga ggacgccccg ctccaggccc acgtcaccaa
    60421 cctggacgcc gacaacttcc tcggccgcat cgcgctgctg cgcgtccacc agggcgagct
    60481 gaagaagggc cagaccgtcg cctggatgaa gcgcgacggg tccgtgcaga acgtgcggat
    60541 ctccgagctg atgatgacgg aggcgctcac ccgcaagccc gccgagaagg ccggccccgg
    60601 tgacatctgc gcggtcgccg gcatcccgga catcatgatc ggcgagaccc tggccgacgt
    60661 ggagaacccg gtcccgctgc cgctgatcac ggtggacgag cccgcgatct ccatgaccat
    60721 cggcaccaac acctccccgc tggtcggccg cggcgccacc ggcaagggcg ccgacaacaa
    60781 ggcggtcgtc aaggaccgca aggtcaccgc ccgtcaggtc aaggaccgcc tggaccgcga
    60841 gctgatcggc aacgtctcgc tccgcgtcct ggacaccgag cgccccgacg cctgggaggt
    60901 gcagggccgc ggtgagctgg cgctggccat cctggtcgag cagatgcgcc gggagggctt
    60961 cgagctgacc atcggcaagc cgcaggtcgt caccaaggag gtcgagggca agacgtacga
    61021 gcccgtcgag cggatgacga tcgacgtgcc cgaggagcac atgggcgcgg tcacgcagct
    61081 catgggcgtg cgcaagggcc ggatggacaa catgtccaac cacggctcgg gctgggtccg
    61141 catggagttc gtggtcccct cccgcggcct gatcggattc cggacggagt tcctcaccca
    61201 gacccgcggc accggcatcg cgcactccat ccacgagggc cacgagccct ggttcggcac
    61261 cctcacgaca cgtaacaacg gctcgctggt cgccgaccgc tcgggtgccg tcaccgcgtt
    61321 cgcgatgacc aacctccagg agcgcggtgt gctcttcacg gaccccggca ccgaggtgta
    61381 cgagggcatg atcgtcggcg agaactcccg cgccgacgac atggacgtga acatcaccaa
    61441 ggagaagaag ctcaccaaca tgcggtcgtc ctcggccgac tcgttcgagg cgatcgtccc
    61501 gccgcgcaag ctctccctgg agcagtccct ggagttctgc cgcgacgacg agtgcgtcga
    61561 ggtgaccccc gaggccgtcc ggatccgcaa ggtgaacctg gacgcccgcg agcgcgcccg
    61621 cgccgccagc cgcgccaagc acggctgacc ccaccgcacg gcggacggca ccggacccca
    61681 cggttcacgt ggggtccggt gccgttcggc gtgttggcga cgcgggcggg agtcgggtgt
    61741 agggaaaacc ctcgatttcc cggcggggcg gcacagggcg ggcagggccg cactaacctg
    61801 cgcggaagca ctccgcccgg agcgccggcg ggcagccccg tccgggggcc gggcggccgg
    61861 cgccgacggc cgtgccgggc gcgggacata cctgcgggtc agcttgcacc ccgtgcacgt
    61921 tacgcgcaat caatttctgt cgcgcggacg tccgctatac ggacggtcac caccgttaga
    61981 tgtgtaacaa gtccgtttcg cagcgatctc gtaccaaacc ctttgtccgg attttgaaag
    62041 atctggcccc tatctgtgat cgaaccgaga cctcgaacct gtggttcgtt ccccggagga
    62101 tggcagatag ttaggcgcgt agagctcgga taaacgggtc acgcgctgac ggggcgcagg
    62161 ctcgcgagcg tgagggtgca cggcgatctc atcaccggcc gatggctgga acgtgacgcg
    62221 tgctcctctt tgcggtgaac cagcggattc atgaggagga acccatgcga ggtgccacaa
    62281 gcgccatatg ggtcgcgtcg tccccgatgg caggtgtagg ccccgcgggt gcgttcagtg
    62341 ccgtcacggt tgatgcggca gcggcccggc gtcgcgaact tccttgacgt cgtgtgccgt
    62401 cggccggccg tcgccggccg tgagccaggg ttctcccggg gccgtgctgc ccctccgtct
    62461 ttgttcccct cgcgcgctgc gaaagacgta cgccgtgcga aggccgtcgg ctcccgcact
    62521 cccgacgacc tccaacctgt gaaatggacg aatcatgacg agtccaatcg agattgaggg
    62581 tgctgaagcc tcttccgtct tggacaaaga gagcgcgccg cagggcgacg ccccgaagcc
    62641 caaggagccg gaagggcgca agcccggcca gttgatgtgg gcgcgcttca agcgcgaccg
    62701 ggccggtgtg atctctgcct tcgtcgtcct gttcttcttc gtgatcgcgg cggcggcgcc
    62761 gctgatctcg atggtctacg gcaaggaccc gtacacgctg tacggtcagg acaaccccga
    62821 cctgctggac atgttcacca tgcccgcggc gccgtacggc ggcatcgacg gcgacttctg
    62881 gttcggcatc gaaccgggcc tgggccgcga cgtgttcacc cagctgctgt acggcatgcg
    62941 caactcgatg gccaccgcgc tggcggcgac catcatcatg acggtgctgg gtgtcctgat
    63001 cggcctggcc ggcggctact tcggcggcaa gatcgactac tggctcggcc ggatcaccga
    63061 cttcttcatg gccctgccca gccagctctt cttcgtcgcc gcgatgcccg tcatcaccac
    63121 ggtgttcgtc gctcccgaca aggagacgcc cacctacgtg cgcgccgccg cgatcatcat
    63181 cgtgctgtcc ttcctgggct ggatgagcat ggcccgcatc gtccgcggtg ccacgatgtc
    63241 cctgcgcgac cgggagttca tcgaggccgc ccgcatctcc ggggcctcgc cctggcgcat
    63301 cctccgcaag gaactgctgc ccaacatcgt cactccgacg ctggtacagg cgacgctcac
    63361 gctgccgagc accatcctca gcatcgcgtt cctgtccttc gtgggcgtgg ggtacgtcga
    63421 gcccacgccg gactggggac ggatgttcgc catcggcgcg gacatcgtcg agcaggaccc
    63481 ctactacatg ctcttccccg gagtcgccat ggtgatcttc atcgtggcct tcaacctcct
    63541 cggtgactcg gtccgggacg ccttcgaccc caagggaaac cgctgaggcc aaggggaacc
    63601 ccccacatcc tcgcccggcc ggttcggcgc cgctcagccc ggcctccggc cacgtaccag
    63661 cagtgctcac tactcacagg caggtggatt cgtcctcatg agcattctcc gtaaccgcac
    63721 cgccacggcc gccatagtcg cggtcgcagc cggcgccctg accctcaccg cctgcggtgg
    63781 tggcgacagc gacagctccg ccaaggacaa cagcaagaag aaggaagacg ccaagtcgca
    63841 gtcgaagccg gtccagatcg gcgacgcgca ggcgtccacc ggcccggccc ccgaggtccc
    63901 gggcgccaag ccgggcggca ccatgaccgt ctaccagacg gcggacttct cccacctgga
    63961 cccgggccag atctacgtct cggacggcaa gctgctcggc cgcctcatct tccgcggtct
    64021 gacccagtac gacgaggacg agaacggcaa cctgaccgtc gtgggcgacc tcgccaccga
    64081 cgcgggcaag cagaccgacg gcggcaagac ctggacgtac accctcaagg acaacttgaa
    64141 ggacgccaac ggcaacccga tcaactcggc ggacatccgc cacacgatcg agcggatgta
    64201 ctccagctac atcaccgacg gcccgacgta cctccagcag tggctgtccg gcgacggcac
    64261 cacctaccgc gacgcctacg cgggtccgga caagggcaag cacctgcccg acaacgtcct
    64321 ggagacgccg gacgacaaga cgatcgtctt ccacttcaag acggctcgcc ccgacctccc
    64381 gcagatgctg accatgcccg gttacagcgt cgtcccggag gagacggaca ccaaggagaa
    64441 gtacgactcc gcgcccgtcg ccgccggtcc gtacaagatc gccgagttca agcccggcaa
    64501 gtcgatgaag ctggtcaaga acacccagtg ggacccgaag tccgactcgg tgcgccacca
    64561 gtacgtcgac ggcttcaaca tcgagatgaa ccacgacgac gaggaccaga ccaagaccct
    64621 cctcgccgac cagggtggcg ccaagaacgc catgatgttc accggccagg tcgccacgac
    64681 gcagctccag aaggtcgtcg gcgacaagga cgcgatgaag aaccgcacga tccagggcta
    64741 cgcgccctac gtgtggcagc tcaacttcaa catgaaccgc gtcaaggaca agaagctccg
    64801 cgacgccatc accctggccc tgccctccga ctcggtcttc aaggccgacg gcggtgccta
    64861 cggcggtgag gtcgccaact cgctgatgtc gcccaccacc ccgggctacg acgaggcgtt
    64921 cgacccgttc ggccgcgcca agaagccgaa cggcgacatc gaggccgcca agaagctcat
    64981 caaggaaggc ggcttcgagg gcaagagcct cgtctacgcc tacgccaaca cccctgagcg
    65041 gcagaagcag gccgtcctga tctccaccgc cctggagaag atcggtctcg acatccagaa
    65101 gaaggagatc gactccgcca cctggtacga gcaggtcggc aaggtcgaca acgggctgga
    65161 cctctacatg accggctggg gccaggactg gccgtccgcc tccacggtca tcccgccggt
    65221 ctacgacggc aagcagatcc aggacggtgc gtcgaactac tcgcacatca acgacgacca
    65281 cgtcaactcc gagatccagc gcatccagca gatcacggac acggcggagg ccaccaaggc
    65341 ctgggcggag ctgaacgagt acatctccaa ggaagtgaac ccggccgccc cgatctacta
    65401 caccaaggtc ttccagatct tcggttcgaa cgtcggcggc atccgctaca gctcggactc
    65461 gagctacgtg gacgtgaccc gggtcttcct caagaagtaa cccgtccggt cgggaaacgg
    65521 tggcgggcgc gctgcggagc gcccgccacc gggcccggac cgactccagc cctccccatc
    65581 cccttgccgc agtcctgaga gcagctgtct gccatgcttc aattcctcat tcgccggtcc
    65641 ttcggcgcgg tgctgatcct ggtgttgatc agtgccttca ccttcttcat gttcttcgcg
    65701 atcccgcagg acccggccat gctggcctgt ggcaagaact gcactccgga cgcgctggag
    65761 atcatccaca agaacctggg cctcgaccag ccggtcacgg tccagtactg gcatttcctg
    65821 gcgggcatct tcaccgggcg cgacttcgcg gtcggtcact gcgacgcccc ctgcttcggc
    65881 gtctccttcg cgaacaacca gaacgtctgg gacacgatcc tcgaccgctt cccgctgacc
    65941 gtctcgctga ccgtcggttc cctgatcgtc ttcctcatcg tcggcctcgg cgccggcctg
    66001 ctggccgcca agaaccgcgg cacctggatc gacaaggtgt tcagctccgg ctcgctggtc
    66061 gtcagctccc tgcagatcta cttcctcggc ccgctcgtcc tgctcgcgct cgtctacagc
    66121 accggctggc tgcagaagcc caagtacgtg ccgatctccg aggacgccgc cggctggttc
    66181 gccggcctgc tgatcccctg gatcgtcatg gcgaccatct tcaccgccaa ctacacccgt
    66241 atgagccggt cgtcgatgat cgagcaacta caggaagagc atgtgagggc ggcccgtgcc
    66301 aagggcatgt cgagcaacta caccttcttc cgctacgcct ggcgcggctc gctcgtgccc
    66361 atcgtcacca tcctcggcat cgacctgtcc gcgctgatgg gcggcggcat ggtgaccgag
    66421 atgaccttcg gcctggccgg catcggccgg ctcgcgctgg agtcggtgat caacaaggac
    66481 ctgccgatgc tgatgggcgt catgctggtc agcgccgcgc tcatcatcgt cttcaacctg
    66541 atcgtggacg ccatgtacgc agtcatcgac ccgcgcgtgc gcctgtccta ggagaaccac
    66601 cgtgaccact cagaccaagc ccgaagaggc cccggccgcc gccgcggggg acgcgtttct
    66661 ctcggtgcgc gacctcaagg tccacttctc caccgagggc ggcgtcgtca aggcggtgga
    66721 cggtctctcc ttcgacctgg agcggggcaa gaccctcggc atcgtcggcg agtccggctc
    66781 cggcaagtcg gtgaccaacc tggccgtcct cggcctgcac gaccgccgca ggaccgccat
    66841 cgacggatcg atcacgctgg acggccagga gctgaccgac gccagtgaga agcagctgga
    66901 gaagctgcgc ggcaagaaga tggcgatgat cttccaggac gcgctgaccg cgctgtcgcc
    66961 gtactacacg gtcggccggc agatcgcgga gccgttcatg aagcacaacg gcgcgtccaa
    67021 gaaggacgcc cgggtgcgcg ccatcgacct gctgcagaag gtcggcatcc cgcacccgca
    67081 gaagcgggtc gacgactacc cgcaccagtt ctccggcggt atgcgccagc gcgccatgat
    67141 cgccatggcc ctgtcctgca acccggacct gctgatcgcg gacgagccca ccacggcgct
    67201 cgacgtgacc gtccaggcgc agatcctcga cctgctcaag gacctccagc aggagttcgg
    67261 ctccgcgatc atcatgatca cccacgacct gggcgtggtc ggcaacatgg ccgacgacat
    67321 catggtcatg tacgcgggcc gggccgtgga gcgcggcacg gtgcgcgagg tgctcaagtc
    67381 cccgcagcac ccgtacacct ggggtctgct gagctcgatg ccgaacctca cgtccgacgt
    67441 cgacgagccg ctgatgccga tcccggggtc gccgccctcg ctgatgaacc cgccctccgg
    67501 gtgcgcgttc cacccgcggt gcggcttcac cgacctggtc tccggcgagc gttgctcggg
    67561 ggagcgtccg acgctcccgc acggccgtgc cgccgcctgc cacctgacgg gagaccagcg
    67621 gcagcaggtg ttcatcgaga agattcagcc ccggctgggc tgagcggaaa ccggcgactg
    67681 gggcatcacc atgagcgaca acagcaagac gaccacagcg gtggccgacg acttcccgca
    67741 gcagcgggac ggcgacaccg cgccgcttct caaggtcagc ggcctctcga agcacttccc
    67801 gatcaagggc ggcttcccga tcaagcgcac cgtcggccac gtcaaggccg tcgacggcgt
    67861 tgatttcgag gtcttcccgg gcgagagcct cggcctcgtc ggcgagtccg gctgcggcaa
    67921 gtcgaccacc ggccggctgc tgacccggct gtacgagccg acccagggca gcatcgagta
    67981 ccggggcaag gacatcaccc gggccaaccg gcgggaactg gcgccggtcc ggtccgagat
    68041 ccagatgatc ttccaggacc cgtacgcgtc cctgaacccg cggcagaccg tcggcacgat
    68101 catctcgggc ccgatggaga tcaacgggat caacccgccc ggcggccggg agaagcgcgt
    68161 ccgcgagctc ctggagatcg tcggtctcaa cccggagcac tacaaccgct tcccgcacga
    68221 gttctccggc ggccagcggc agcgcatcgg ggtggcgcgc gccgtcgcgc tgcagccgaa
    68281 gctcatcgtc gccgacgagc cggtctcggc cctcgacgtg tcgatccagg cccaggtggt
    68341 gaacctgctg caggaggtgc agcgggagat gggcatcgcg ttcgtcttca tcgcccacga
    68401 cctggcgatc gtgcggcact tctcgcagcg cgtcgcggtg atgtacctgg gcaagatcgt
    68461 ggagatcgcg gaccgcgact cgctctacaa ccgcccccgt cacccgtaca cgcacgcgct
    68521 gctgtcggcc gtgccggaga cggacctcga cgccgagaag cgggagcgga tccggctcga
    68581 gggcgacgtg ccctcgccga tctcgccgcc ctccggctgc cggttccgca cccggtgctg
    68641 gaaggcgcag gacaagtgcg ccaccgagga gccgccgctg gtgcagctct ccgggaaccg
    68701 ggagggccac ctgacggcct gccacttccc cgaggagggc tcgacggagg ccagggccga
    68761 ggacatcgtc atggacccgg gtctgaaggc gatggaggac ggcgccgacg gcggcgcgac
    68821 cctctccaag ggctgagcac agaaggcagc agggaagggc ggcggcggga gcaggactcc
    68881 cgccgccgcc cttccgtatg ccgccacacc tcccgcaccc gtccggagga caccggcaac
    68941 ccgtatggac cggacgggtg tgcgcccccg agtacgccct tcgaagctgg accggaacgg
    69001 accagcggac gagtcagggc acgaggaggc actccatgcg cggagccacg cacgccagat
    69061 gggccgcttg cgcggcggcg gtagccctcg cggcgacggc ctgcggcggc gggggcgggg
    69121 acggaggcag cggcggcggc agcggcggcg tgctcagctc ctcctggggc gacccccaga
    69181 acccgctgga gccggccaac accaacgagg tgcagggcgg caaggtcctc gacatgatct
    69241 tccgggggct gaagaagtac gaccccggga ccggcgaggc gcagaacatg ctcgccgaga
    69301 agatcgacac ctccgactcg cagaacttca ccgtcaccgt caaggacggc tggaccttca
    69361 gcaacggcga gaaggtcacc gcgcagtcct tcgtggacgc ctggaactac ggcgcgagcc
    69421 tgaagaacaa ccagcgcaac gcgtacttct tcgcctacat cgacggctac gacaaggtgc
    69481 accccgaaag cggctcgcag agcaccgaca cgctctcggg gctgaaggtg accggccccc
    69541 gcaccttcac gatcaagctc agccagaagt tctccacgtt ccccgacacc ctcggctatc
    69601 cggccttcgc gccgctgccc aaggcgttct tcgacgacca cgacgcctgg ctgaagaagc
    69661 ccgtcggcaa cggcccctac caggtcgaca actacacccg cggctcccag atgtccctgc
    69721 gcaagtggga cgactacccc ggcccggaca aggcgcagaa cggcggcgtg gacctcaagg
    69781 tctacaccga caacaacacc gcctacaccg acctgatcgc gggcaacctc gacctcgtcg
    69841 acgacgtccc ggcctcccag ctcaagaacg tcaagaacga cctcggcgac cggtacatca
    69901 acaccccggc gggcatcatc cagaccctcg ccttcccgtt ctacgacaac gactggaaca
    69961 agtccggctc ggagaaggtc cgcaagggcc tgtccatggc gatcgaccgc aagcagatca
    70021 ccgacaccat cttccagaac acccgcaccc cggccaccga ctggacctca ccggtcctcg
    70081 gcaaggacgg cggctacaag ccgggcctgt gcggggacgc ctgcgagtac aacgccgcgg
    70141 aggccaagaa gctggtcaag gagggcggcg gactccccgg cgggcaggtc aagatcacct
    70201 acaacgccga caccggctcc cacaagcagt gggtcgacgc ggtctgcaac tccatcaaca
    70261 acgccctgga caacgaccgc gcctgcgccg ggaacccggt cggcaccttc gccgacttcc
    70321 gcaaccagat caccaaccag aagatgagcg gccccttccg cgcgggctgg cagatggact
    70381 acccgctcat ccagaacttc ctccagccgc tgtactacac caacgcctcc tccaacgacg
    70441 gcaagtggtc cagcaagaag ttcgacgacc tcgtcgacca ggccaacgcc gagaccgaca
    70501 ccgccaaggc cgtcggcctc ttccagcagg ccgaggaggt cctcagggac gacatggggg
    70561 ccatcccgct ctggtaccag aacggcagcg caggctactc cgaccggctc tccaacgtga
    70621 agctcaaccc gttcagcgtc ccggtctaca acgagatcaa ggtcggctga gggggcgcca
    70681 tgggacgcta cgtcgtccgg cggctgctcc agatgatccc ggtcttcatc ggggccacgc
    70741 tgctgatctt cctgatggtc aacgtgatgg gcgaccccat cgcgggcctg tgcggcgacc
    70801 gggagtgcga cccggcgacg gccgcgcagc tgcggcacga gttcggcctc gaccagccgg
    70861 tgtggcagca gtacgccacc tacatgggca acgtcttcac cggcgacttc ggcaccgcct
    70921 tcaacggcca gccggtcacc gagctgatgg ggacggcgtt cccggtcacc atccggctca
    70981 ccatcgtcgc gatcctcttc gagatcgtcg tcggcatcat cctgggcgtc ctcaccggcc
    71041 tgcgccgcgg ccgtcccgtc gacaccgggg tgctgctgct gaccctcgtc gtcatctccg
    71101 tgcccacctt cgtcaccggc ctgctgctcc agctgctgct cggcgtcaag tggggctgga
    71161 tcgacccggc cgtctcctcc gaggcggcct tcggcgagct gatcgtcccc ggcctggtcc
    71221 tcgcctcggt ctcgctggcc tacgtcaccc ggctgacccg cacctccatc gccgagaacc
    71281 ggcgctccga ctacgtccgc accgccatcg ccaagggcct gccccgccac cgggtcatca
    71341 cccggcacct gctgcgcaac tccctcatcc ccgtcgtcac cttcatcggc accgacatcg
    71401 gcgcgctgat gggcggcgcc atcgtcaccg agcggatctt caacatccac ggcgtcggct
    71461 accagctcta ccagggcatc ctgcgccaga acacccagac cgtcgtcggc ttcgtcaccg
    71521 tcctggtcct cgtcttcctc gtcgccaacc tcgtcgtcga cctcctgtac gccgtactcg
    71581 acccgaggat ccgctatgcc tgaacaggag ccctacgagc ccgagcgcgc catcgccggc
    71641 accggcatgg gcggcacgat ggacctcggc gccagcgagg cggtcacgct ggagcagccg
    71701 ccgggcccgg acggggccga cccccgggac aaaccccgca gcctgtggac cgacgcctgg
    71761 cacgacctgc gccgcaaccc cgtcttcatc atctcggcgc tggtgatcat cttcctgatc
    71821 gtcatctcca tctggccgtc gctgatcgcc tccggcagcc ccctcaagtg cgacctggcc
    71881 aaggcccagg aaggctccca gcccggccac cccttcggct tcaacggcca gggctgcgac
    71941 gtctacaccc gcaccgtcta cggcgcccgc acctcggtcg cggtcggcat cctggccact
    72001 ctcggcgtcg ccctcctcgg cagcgtcctc ggcggcctcg ccgggttctt cggcggcggc
    72061 ggggacgcgg tcctgtcccg gatcaccgac atctttttcg cgatcccggt cgtcctgggc
    72121 ggcctcgtcc tgctctccgt catcaccagc aacaccatct ggccggtcat cggcttcatc
    72181 gtgctgctcg gctggccaca gatctcccgc atcgcccgcg gctccgtcat caccgccaaa
    72241 cagaacgact acgtgcaggc ggcgcgggcg ctgggcgcct ccaactcccg gctcctgctg
    72301 cgccacatcg cgcccaacgc cgtcgcgccc gtcatcgtcg tggcgaccat cgcgctcggc
    72361 acctacatct ccctggaggc gaccctgtcc ttcctcggcg tcggcctgaa gccgcccagc
    72421 gtctcctggg gcatcgacat ctcctccgcc gccccctacg tgcgcaacgc cccgcacgcg
    72481 ctgctgtggc cgtccggggc gctcgccatc accgtcctcg cgttcatcat gctcggcgac
    72541 gcggtgcgcg acgccctcga cccgaagctg aggtgagcga ccgcatgctg ctcgaagtgc
    72601 gcgacctgca cgtggagttc caca
//
