LOCUS       NC_003888              29788 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    .
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2023-11-22 14:16:39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3024894
            Orig. end    :: 3054682
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..29788
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:15788]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..15788
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     cand_cluster    1..29788
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..29788
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="9"
                     /rules="IucA_IucC"
                     /tool="antismash"
     gene            complement(609..1766)
                     /db_xref="GeneID:1098208"
                     /gene_synonym="acdH2; SCC105.05c"
                     /locus_tag="SCO2774"
     CDS             complement(609..1766)
                     /codon_start=1
                     /db_xref="GeneID:1098208"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 383.1; E-value:
                     2.3e-116)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="acdH2; SCC105.05c"
                     /locus_tag="SCO2774"
                     /note="SCC105.05c, acdH2, probable acyl-CoA dehydrogenase,
                     len: 385 aa; similar to TR:Q9X7Y2 (EMBL:AL049485)
                     Streptomyces coelicolor probable acyl-CoA dehydrogenase
                     SC6A5.36, 382 aa; fasta scores: opt: 1170 z-score: 1351.4
                     E(): 0; 47.9% identity in 382 aa overlap. Contains Pfam
                     match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase
                     and match to Prosite entry PS00073 Acyl-CoA dehydrogenases
                     signature 2"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="NP_627004.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.6e-30, bitscore:
                     104.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.2e-25, bitscore:
                     88.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4e-46, bitscore:
                     155.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTVFNEDHEAFRETLRAFIEAEVVPVYDDWFAAGQAPREFYYK
                     LGELGIFGINVPEEFGGAGMDSHKFEAVLYEETARAGVQFGGSGVHVLLALPYINMLAT
                     DEQKKRYLPKFVTGEEMWAIAMTEPGTGSDLAGMKSTAKLSEDGTHYVLNGAKTFITGG
                     VHADRVIVCARTDAPTAEDRRHGISLFAVDTKSEGYSVGRKLDKLGLRTSDTAELAFVD
                     VKVPVEDLLGEENKGFSYLGHNLASERWGIAFGAYAQAKAAVRFAKQYVQDRTVFGKPV
                     AHFQNTKFELAACQAEVDAAEAVVDRATEALDAGELTPAEAASAKLFCTEVAHRVIDRC
                     LQLHGGYGYMNEYPIARLYADNRVNRIYGGTSEIMKSIIAKNMGL"
     PFAM_domain     complement(618..1064)
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00441.27"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2774_0252"
                     /evalue="1.00E-45"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO2774"
                     /locus_tag="SCO2774"
                     /protein_end="383"
                     /protein_start="234"
                     /score="155.8"
                     /tool="antismash"
                     /translation="NKGFSYLGHNLASERWGIAFGAYAQAKAAVRFAKQYVQDRTVFGK
                     PVAHFQNTKFELAACQAEVDAAEAVVDRATEALDAGELTPAEAASAKLFCTEVAHRVID
                     RCLQLHGGYGYMNEYPIARLYADNRVNRIYGGTSEIMKSIIAKNM"
     misc_feature    complement(624..1751)
                     /gene_synonym="acdH2; SCC105.05c"
                     /locus_tag="SCO2774"
                     /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA
                     dehydrogenase, score 409.10, E-value 3.5e-119"
     misc_feature    complement(684..743)
                     /gene_synonym="acdH2; SCC105.05c"
                     /locus_tag="SCO2774"
                     /note="PS00073 Acyl-CoA dehydrogenases signature 2"
     PFAM_domain     complement(1098..1400)
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02770.22"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2774_0251"
                     /evalue="9.20E-26"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO2774"
                     /locus_tag="SCO2774"
                     /protein_end="223"
                     /protein_start="122"
                     /score="90.0"
                     /tool="antismash"
                     /translation="AIAMTEPGTGSDLAGMKSTAKLSEDGTHYVLNGAKTFITGGVHAD
                     RVIVCARTDAPTAEDRRHGISLFAVDTKSEGYSVGRKLDKLGLRTSDTAELAFVDV"
     PFAM_domain     complement(1410..1748)
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02771.19"
                     /db_xref="GO:0016627"
                     /db_xref="GO:0050660"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2774_0250"
                     /evalue="2.90E-30"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /gene_ontologies="GO:0050660: flavin adenine dinucleotide
                     binding"
                     /label="SCO2774"
                     /locus_tag="SCO2774"
                     /protein_end="119"
                     /protein_start="6"
                     /score="105.3"
                     /tool="antismash"
                     /translation="NEDHEAFRETLRAFIEAEVVPVYDDWFAAGQAPREFYYKLGELGI
                     FGINVPEEFGGAGMDSHKFEAVLYEETARAGVQFGGSGVHVLLALPYINMLATDEQKKR
                     YLPKFVTGE"
     regulatory      complement(1774..1778)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(1896..2522)
                     /db_xref="GeneID:1098209"
                     /gene_synonym="SCC105.06c"
                     /locus_tag="SCO2775"
     CDS             complement(1896..2522)
                     /codon_start=1
                     /db_xref="GeneID:1098209"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 91; E-value: 2.2e-27)"
                     /gene_kind="regulatory"
                     /gene_synonym="SCC105.06c"
                     /locus_tag="SCO2775"
                     /note="SCC105.06, possible tetR-family regulatory protein,
                     len: 208 aa; similar to TR:AAF11696 (EMBL:AE002049)
                     Deinococcus radiodurans transcriptional regulatory protein,
                     tetR family DR2148, 240 aa; fasta scores: opt: 189 z-score:
                     219.0 E(): 9.3e-05; 31.7% identity in 205 aa overlap.
                     Contains Pfam match to entry PF00440 tetR, Bacterial
                     regulatory proteins, tetR family"
                     /product="TetR family transcriptional regulator"
                     /protein_id="NP_627005.1"
                     /transl_table=11
                     /translation="MATRTDAPTRREQILKEAARLFAERGFHGVGVDEIGAAVGISGPG
                     LYRHFPGKDAMLAELLVGISDSLLTGAKRRLAEADGAAGSRAGTGPTGPGAVLDSLIAG
                     HIDFALDDRPLITLHDRELDRLRDADRKMVRQLQRQYVELWVGVLREVYPAVAEPAARS
                     AVHSVFGLLNSTPHLGRPGSLPGRAVTASLLHRMARGAFAAVGEA"
     PFAM_domain     complement(1995..2243)
                     /aSDomain="TetR_C_24"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF17932.4"
                     /description="Tetracyclin repressor-like, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2775_0254"
                     /evalue="4.00E-07"
                     /label="SCO2775"
                     /locus_tag="SCO2775"
                     /protein_end="176"
                     /protein_start="93"
                     /score="30.4"
                     /tool="antismash"
                     /translation="PGAVLDSLIAGHIDFALDDRPLITLHDRELDRLRDADRKMVRQLQ
                     RQYVELWVGVLREVYPAVAEPAARSAVHSVFGLLNSTP"
     misc_feature    complement(2343..2483)
                     /gene_synonym="SCC105.06c"
                     /locus_tag="SCO2775"
                     /note="Pfam match to entry PF00440 tetR, Bacterial
                     regulatory proteins, tetR family, score 43.90, E-value
                     1.9e-10"
     PFAM_domain     complement(2343..2483)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00440.26"
                     /db_xref="GO:0003677"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2775_0253"
                     /evalue="4.60E-17"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /label="SCO2775"
                     /locus_tag="SCO2775"
                     /protein_end="60"
                     /protein_start="13"
                     /score="61.7"
                     /tool="antismash"
                     /translation="ILKEAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFPGKDAMLA
                     EL"
     regulatory      2606..2609
                     /regulatory_class="ribosome_binding_site"
     gene            2620..4236
                     /db_xref="GeneID:1098210"
                     /gene_synonym="accD1; SCC105.07"
                     /locus_tag="SCO2776"
     CDS             2620..4236
                     /codon_start=1
                     /db_xref="GeneID:1098210"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 543.4; E-value: 9.8e-165)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="accD1; SCC105.07"
                     /locus_tag="SCO2776"
                     /note="SCC105.07, accD1, acetyl/propionyl CoA carboxylase,
                     beta subunit, len: 538 aa; similar to TR:O06165
                     (EMBL:Z95556) Mycobacterium tuberculosis, hypothetical 56.7
                     kD protein MTCY07A7.08c, 529 aa; fasta scores: opt: 2749
                     z-score: 3110.3 E(): 0; 76.5% identity in 532 aa overlap
                     and to TR:AAF35258 (EMBL:AF059510) Arabidopsis thaliana
                     3-methylcrotonyl-CoA carboxylase non-biotinylated subunit
                     (EC 6.4.1.4) MccB, 587 aa; fasta scores: opt: 2185 z-score:
                     2471.8 E(): 0; 60.4% identity in 540 aa overlap. Contains
                     Pfam match to entry PF01039 Carboxyl_trans, Carboxyl
                     transferase domain"
                     /product="acetyl/propionyl CoA carboxylase subunit beta"
                     /protein_id="NP_627006.1"
                     /transl_table=11
                     /translation="MHEAPELTTAADPASEAFRANEEAHAALVQELRAKLAAARLGGGE
                     RARARHTARGKLLPRDRVDTLLDPGSPFLELAPLAADGLYDGAAPAAGVIAGIGRVSGR
                     ECVIVANDATVKGGTYYPMTVKKHLRAQEVALENRLPCLYLVDSGGAFLPMQDEVFPDR
                     EHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLV
                     KAATGEVVTAEELGGGEVHSRVSGVTDHLAEDDPHALRIVRQIVSTLPERGALPWGVEA
                     AAEPKADPQDLYGVVPVDSRTPYDVREVIARVVDGSRFAEFKSEYGQTLVTGFARIHGH
                     PVGIVANNGILFSESAQKGAHFIELCDQRGIPLVFLQNISGFMVGRDYEAGGIAKHGAK
                     MVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMGGEQAASVLA
                     TVKRDQLEGRGEEWPAEEEESFKAPVRAQYERQGNAYYATARLWDDGVIEPADTRQVLG
                     LALTACANAPLGEPRFGVFRM"
     misc_feature    2722..4233
                     /gene_synonym="accD1; SCC105.07"
                     /locus_tag="SCO2776"
                     /note="Pfam match to entry PF01039 Carboxyl_trans, Carboxyl
                     transferase domain, score 735.40, E-value 2.6e-217"
     PFAM_domain     2770..4200
                     /aSDomain="Carboxyl_trans"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01039.25"
                     /description="Carboxyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2776_0255"
                     /evalue="2.10E-154"
                     /label="SCO2776"
                     /locus_tag="SCO2776"
                     /protein_end="527"
                     /protein_start="50"
                     /score="515.0"
                     /tool="antismash"
                     /translation="HTARGKLLPRDRVDTLLDPGSPFLELAPLAADGLYDGAAPAAGVI
                     AGIGRVSGRECVIVANDATVKGGTYYPMTVKKHLRAQEVALENRLPCLYLVDSGGAFLP
                     MQDEVFPDREHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGT
                     IFLGGPPLVKAATGEVVTAEELGGGEVHSRVSGVTDHLAEDDPHALRIVRQIVSTLPER
                     GALPWGVEAAAEPKADPQDLYGVVPVDSRTPYDVREVIARVVDGSRFAEFKSEYGQTLV
                     TGFARIHGHPVGIVANNGILFSESAQKGAHFIELCDQRGIPLVFLQNISGFMVGRDYEA
                     GGIAKHGAKMVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMG
                     GEQAASVLATVKRDQLEGRGEEWPAEEEESFKAPVRAQYERQGNAYYATARLWDDGVIE
                     PADTRQVLGLALTACANAP"
     regulatory      4259..4264
                     /regulatory_class="ribosome_binding_site"
     PFAM_domain     4275..4604
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00289.25"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2777_0256"
                     /evalue="7.40E-44"
                     /label="SCO2777"
                     /locus_tag="SCO2777"
                     /protein_end="110"
                     /protein_start="0"
                     /score="148.9"
                     /tool="antismash"
                     /translation="MFDTVLVANRGEIAVRVIRTLRSMGVRSVAVFSDADADARHVREA
                     DDAVRIGPAPATESYLSVERLLAAAARTGAQAVHPGYGFLAENAGFARACEEAGLVFIG
                     PSADAI"
     gene            4275..6215
                     /db_xref="GeneID:1098211"
                     /gene_synonym="accC; SCC105.08"
                     /locus_tag="SCO2777"
     CDS             4275..6215
                     /codon_start=1
                     /db_xref="GeneID:1098211"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     731.9; E-value: 1.2e-221)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="accC; SCC105.08"
                     /locus_tag="SCO2777"
                     /note="SCC105.08, accC, acetyl/propionyl CoA carboxylase
                     alpha subunit, len: 646 aa; similar to SW:PCCA_HUMAN
                     (EMBL:X14608) Homo sapiens propionyl-CoA carboxylase alpha
                     chain precursor (EC 6.4.1.3) PccA, 703 aa; fasta scores:
                     opt: 1539 z-score: 1630.1 E(): 0; 43.0% identity in 665 aa
                     overlap and to SW:ACCC_ECOLI (EMBL:M79446) Escherichia coli
                     biotin carboxylase (EC 6.3.4.14), alpha subunit of acetyl
                     CoA carboxylase (EC 6.4.1.2) AccC or FabG, 449 aa; fasta
                     scores: opt: 1439 z-score: 1527.1 E(): 0; 47.9% identity in
                     451 aa overlap and to N-terminal region of TR:CAB59603
                     (EMBL:AL132662) Streptomyces coelicolor pyruvate
                     carboxylase SCF11.26c, 1124 aa; fasta scores: opt: 1367
                     z-score: 1204.5 E(): 0; 44.3% identity in 569 aa overlap.
                     Contains Pfam matches to entries PF00289 CPSase_L_chain,
                     Carbamoyl-phosphate synthase (CPSase) and Pfam match to
                     entry PF00364 biotin_lipoyl, Biotin-requiring enzymes and
                     matches to Prosite entries PS00867 Carbamoyl-phosphate
                     synthase subdomain signature 2 and PS00188 Biotin-requiring
                     enzymes attachment site"
                     /product="acetyl/propionyl CoA carboxylase subunit alpha"
                     /protein_id="NP_627007.1"
                     /sec_met_domain="ATP-grasp (E-value: 3.6e-06, bitscore:
                     25.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 6.3e-09,
                     bitscore: 34.4, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDTVLVANRGEIAVRVIRTLRSMGVRSVAVFSDADADARHVREA
                     DDAVRIGPAPATESYLSVERLLAAAARTGAQAVHPGYGFLAENAGFARACEEAGLVFIG
                     PSADAIALMGDKIRAKETVRAAGVPVVPGSSGSGLTDEQLADAAREIGTPVLLKPSAGG
                     GGKGMRLVRDTAVLADEIAAARREARASFGDDTLLVERWIDRPRHIEIQVLADGHGGVV
                     HLGERECSLQRRHQKVIEEAPSVLLDEATRAAMGEAAVQAARSCGYRGAGTVEFIVPGS
                     DPSQYYFMEMNTRLQVEHPVTELVTGLDLVEWQLRVAAGEPLGFGQEDVRLTGHAIEAR
                     LCAEDPARGFLPSGGTVLRLREPEGDGVRTDSGLSEGTEVGSLYDPMLSKVIAYGPDRE
                     TALRRLRAALAGTVTLGVQTNAGFLRRLLAHPAVVAGELDTGLVEREVDGLVATDVPEE
                     VYEAAAAVRLEALRPRGDGWTDPFSVPSGWRMGGEPKAAAFHLRVTDPVEHTPRGTHTV
                     TGDRVTVTLDGVRHTFHRAADWLGRDGDAWQVRDHDPVAASLNRSAHAGADSLTAPMPG
                     TVTVVKVAVGDEVSAGQSLLVVEAMKMEHVISAPHAGTVAELDVAPGTTVAMDQVLAVI
                     APTDDATEETA"
     misc_feature    4284..5393
                     /gene_synonym="accC; SCC105.08"
                     /locus_tag="SCO2777"
                     /note="Pfam match to entry PF00289 CPSase_L_chain,
                     Carbamoyl-phosphate synthase (CPSase), score 605.50,
                     E-value 3.1e-178"
     PFAM_domain     4617..5243
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02786.20"
                     /db_xref="GO:0005524"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2777_0257"
                     /evalue="2.40E-77"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /label="SCO2777"
                     /locus_tag="SCO2777"
                     /protein_end="323"
                     /protein_start="114"
                     /score="259.3"
                     /tool="antismash"
                     /translation="DKIRAKETVRAAGVPVVPGSSGSGLTDEQLADAAREIGTPVLLKP
                     SAGGGGKGMRLVRDTAVLADEIAAARREARASFGDDTLLVERWIDRPRHIEIQVLADGH
                     GGVVHLGERECSLQRRHQKVIEEAPSVLLDEATRAAMGEAAVQAARSCGYRGAGTVEFI
                     VPGSDPSQYYFMEMNTRLQVEHPVTELVTGLDLVEWQLRVAAGEPL"
     misc_feature    5136..5159
                     /gene_synonym="accC; SCC105.08"
                     /locus_tag="SCO2777"
                     /note="PS00867 Carbamoyl-phosphate synthase subdomain
                     signature 2"
     PFAM_domain     5286..5606
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02785.22"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2777_0258"
                     /evalue="3.20E-34"
                     /label="SCO2777"
                     /locus_tag="SCO2777"
                     /protein_end="444"
                     /protein_start="337"
                     /score="117.4"
                     /tool="antismash"
                     /translation="EARLCAEDPARGFLPSGGTVLRLREPEGDGVRTDSGLSEGTEVGS
                     LYDPMLSKVIAYGPDRETALRRLRAALAGTVTLGVQTNAGFLRRLLAHPAVVAGELDTG
                     LVE"
     misc_feature    5976..6179
                     /gene_synonym="accC; SCC105.08"
                     /locus_tag="SCO2777"
                     /note="Pfam match to entry PF00364 biotin_lipoyl,
                     Biotin-requiring enzymes, score 87.20, E-value 3.3e-22"
     PFAM_domain     5982..6179
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00364.25"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2777_0259"
                     /evalue="7.10E-19"
                     /label="SCO2777"
                     /locus_tag="SCO2777"
                     /protein_end="635"
                     /protein_start="569"
                     /score="67.6"
                     /tool="antismash"
                     /translation="LTAPMPGTVTVVKVAVGDEVSAGQSLLVVEAMKMEHVISAPHAGT
                     VAELDVAPGTTVAMDQVLAVI"
     misc_feature    6048..6101
                     /gene_synonym="accC; SCC105.08"
                     /locus_tag="SCO2777"
                     /note="PS00188 Biotin-requiring enzymes attachment site"
     regulatory      6200..6205
                     /gene_synonym="accC; SCC105.08"
                     /locus_tag="SCO2777"
                     /regulatory_class="ribosome_binding_site"
     gene            6212..7165
                     /db_xref="GeneID:1098212"
                     /gene_synonym="hmgL; SCC105.09"
                     /locus_tag="SCO2778"
     CDS             6212..7165
                     /codon_start=1
                     /db_xref="GeneID:1098212"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 227.6;
                     E-value: 5.2e-69)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="hmgL; SCC105.09"
                     /locus_tag="SCO2778"
                     /note="SCC105.09, hmgL, hydroxymethylglutaryl-CoA lyase,
                     len: 317 aa; similar to TR:P95639 (EMBL:U41280)
                     Rhodospirillum rubrum hydroxymethylglutaryl-CoA lyase
                     (EC4.1.3.4) HmgL, 303 aa; fasta scores: opt: 924 z-score:
                     1043.1 E(): 0; 51.2% identity in 297 aa overlap and to
                     SW:HMGL_RAT (EMBL:Y10054) Rattus norvegicus
                     hydroxymethylglutaryl-CoA lyase, mitochondrial precursor
                     (EC 4.1.3.4) HmgCL, 325 aa; fasta scores: opt: 983 z-score:
                     1108.8 E(): 0; 52.7% identity in 296 aa overlap. Contains
                     Pfam match to entry PF00682 HMGL-like, HMGL-like"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="NP_627008.1"
                     /sec_met_domain="HMGL-like (E-value: 3.1e-46, bitscore:
                     156.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAPEPGLPMAVPAEGLPARVRIHEVGARDGLQNEKATVPTAVKA
                     EFIRRLAGTGLTTIEATSFVHPKWVPQLADAEDLYPRISGLPVELPVLVPNERGLDRAL
                     ALGARRVAVFASATESFAKANLNRTVDEALAMFEPVVTRAKAQGDDVRVRGYLSMCFGD
                     PWEGPVAVPQVVRVCRALLDMGCDELSLGDTIGVATPGHVTALLTALTGAGVPVSALGV
                     HFHDTYGQALANTLAALQRGVTTVDASAGGLGGCPFAKSATGNLATEDLVWMLRGLGID
                     TGVDLGRLVATSVWMAAHLGRPSPSRTVRALSHQES"
     PFAM_domain     6269..7090
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00682.22"
                     /db_xref="GO:0003824"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2778_0260"
                     /evalue="2.10E-45"
                     /gene_ontologies="GO:0003824: catalytic activity"
                     /label="SCO2778"
                     /locus_tag="SCO2778"
                     /protein_end="293"
                     /protein_start="19"
                     /score="155.5"
                     /tool="antismash"
                     /translation="RVRIHEVGARDGLQNEKATVPTAVKAEFIRRLAGTGLTTIEATSF
                     VHPKWVPQLADAEDLYPRISGLPVELPVLVPNERGLDRALALGARRVAVFASATESFAK
                     ANLNRTVDEALAMFEPVVTRAKAQGDDVRVRGYLSMCFGDPWEGPVAVPQVVRVCRALL
                     DMGCDELSLGDTIGVATPGHVTALLTALTGAGVPVSALGVHFHDTYGQALANTLAALQR
                     GVTTVDASAGGLGGCPFAKSATGNLATEDLVWMLRGLGIDTGVDLGRLVATS"
     misc_feature    6296..7144
                     /gene_synonym="hmgL; SCC105.09"
                     /locus_tag="SCO2778"
                     /note="Pfam match to entry PF00682 HMGL-like, HMGL-like,
                     score 226.60, E-value 3.6e-64"
     misc_feature    6907..8639
                     /note="previously sequenced fragment EMBL:AF142581
                     Streptomyces coelicolor acyl-CoA dehydrogenase (acdH) gene,
                     complete cds."
     gene            7171..8331
                     /db_xref="GeneID:1098213"
                     /gene_synonym="acdH; SCC105.10"
                     /locus_tag="SCO2779"
     CDS             7171..8331
                     /codon_start=1
                     /db_xref="GeneID:1098213"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 398; E-value:
                     7.1e-121)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="acdH; SCC105.10"
                     /locus_tag="SCO2779"
                     /note="SCC105.10, acdH, acyl-CoA dehydrogenase, len: 386
                     aa; identical to previously sequenced TR:Q9XCG6
                     (EMBL:AF142581) Streptomyces coelicolor acyl-CoA
                     dehydrogenase AcdH, 386 aa. Contains Pfam match to entry
                     PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase and matches to
                     Prosite entries PS00072 Acyl-CoA dehydrogenases signature 1
                     and PS00073 Acyl-CoA dehydrogenases signature 2"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="NP_627009.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.5e-36, bitscore:
                     123.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.8e-21, bitscore:
                     73.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.1e-48, bitscore:
                     164.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHKLSPELEELRRTVEQFAHDVVAPKIGDFYERHEFPYEIVREM
                     GRMGLFGLPFPEEYGGMGGDYFALGVALEELARVDSSVAITLEAGVSLGAMPLHLFGTE
                     EQKREWLPRLCSGEILGAFGLTEPDGGSDAGATRTTARLDEATNEWVINGTKCFITNSG
                     TDITGLVTVTAVTGRKPDGRPLISSIIVPSGTPGFTVAAPYSKVGWNASDTRELSFADV
                     RVPAANLLGELGRGYAQFLRILDEGRVAIAALGTGLAQGCVDESVAYAKERHAFGRPIG
                     ANQAIQFKIADMEMKAHTARLAWRDAASRLVAGEPFKKEAALAKLYSSTVAVDNARDAT
                     QVHGGYGFMNEYPVARMWRDAKILEIGEGTSEVQRMLIARELGLVG"
     misc_feature    7183..8310
                     /gene_synonym="acdH; SCC105.10"
                     /locus_tag="SCO2779"
                     /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA
                     dehydrogenase, score 464.70, E-value 7.6e-136"
     PFAM_domain     7186..7524
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02771.19"
                     /db_xref="GO:0016627"
                     /db_xref="GO:0050660"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2779_0261"
                     /evalue="8.30E-37"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /gene_ontologies="GO:0050660: flavin adenine dinucleotide
                     binding"
                     /label="SCO2779"
                     /locus_tag="SCO2779"
                     /protein_end="118"
                     /protein_start="5"
                     /score="126.4"
                     /tool="antismash"
                     /translation="SPELEELRRTVEQFAHDVVAPKIGDFYERHEFPYEIVREMGRMGL
                     FGLPFPEEYGGMGGDYFALGVALEELARVDSSVAITLEAGVSLGAMPLHLFGTEEQKRE
                     WLPRLCSGE"
     PFAM_domain     7534..7836
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02770.22"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2779_0262"
                     /evalue="3.00E-20"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO2779"
                     /locus_tag="SCO2779"
                     /protein_end="222"
                     /protein_start="121"
                     /score="72.3"
                     /tool="antismash"
                     /translation="AFGLTEPDGGSDAGATRTTARLDEATNEWVINGTKCFITNSGTDI
                     TGLVTVTAVTGRKPDGRPLISSIIVPSGTPGFTVAAPYSKVGWNASDTRELSFADV"
     misc_feature    7540..7578
                     /gene_synonym="acdH; SCC105.10"
                     /locus_tag="SCO2779"
                     /note="PS00072 Acyl-CoA dehydrogenases signature 1"
     PFAM_domain     7870..8316
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00441.27"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2779_0263"
                     /evalue="2.80E-48"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO2779"
                     /locus_tag="SCO2779"
                     /protein_end="382"
                     /protein_start="233"
                     /score="164.1"
                     /tool="antismash"
                     /translation="GRGYAQFLRILDEGRVAIAALGTGLAQGCVDESVAYAKERHAFGR
                     PIGANQAIQFKIADMEMKAHTARLAWRDAASRLVAGEPFKKEAALAKLYSSTVAVDNAR
                     DATQVHGGYGFMNEYPVARMWRDAKILEIGEGTSEVQRMLIAREL"
     misc_feature    8191..8250
                     /gene_synonym="acdH; SCC105.10"
                     /locus_tag="SCO2779"
                     /note="PS00073 Acyl-CoA dehydrogenases signature 2"
     misc_feature    8375..8388
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    8386..8404
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 30.94"
                     /tool="antismash"
     gene            8461..9510
                     /db_xref="GeneID:1098214"
                     /gene_synonym="SCC105.11"
                     /locus_tag="SCO2780"
     CDS             8461..9510
                     /codon_start=1
                     /db_xref="GeneID:1098214"
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 90; E-value: 2.2e-27)"
                     /gene_kind="transport"
                     /gene_synonym="SCC105.11"
                     /locus_tag="SCO2780"
                     /note="SCC105.11, possible hypothetical protein, len: 349
                     aa; similar to TR:CAB53324 (EMBL:AL109974) Streptomyces
                     coelicolor iron-siderophore binding lipoprotein SCF34.13c,
                     350 aa; fasta scores: opt: 288 z-score: 297.2 E(): 4.1e-09;
                     28.3% identity in 332 aa overlap. Contains possible
                     N-terminal region signal peptide sequence"
                     /product="hypothetical protein"
                     /protein_id="NP_627010.1"
                     /transl_table=11
                     /translation="MSHASATHPTRRGILAAGGALGLGAVLAACGDGDGKSDGAGDGSG
                     GAAKSGPWSFKDDRGTTVKLDKVPANIVAFTGVAAALFDYGVEVKGVFGPTTTKDGKPD
                     VQAGDLDVDKVTVLGNEWGKLNVEKYASLAPEVLITTTFDTAGTLWSVPEESKDKVAKL
                     APSVAISVFDRQLTQPLQRMWELAESLGADMKAKKVTDAKAAFDKAAARLRAAAKAKPE
                     IRVLAGSASPDLFYVSGTNLSVDLEYFKALGVNFVEPSEDAKKATGGWFESLSWENVDK
                     YPADVIIMDDRASTIQPADITEGTWKQLPAVKAGQVIARSPEPILSYDKCTPLLDNLAE
                     AIENAKKVG"
     PFAM_domain     8689..9417
                     /aSDomain="Peripla_BP_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01497.21"
                     /description="Periplasmic binding protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2780_0264"
                     /evalue="1.60E-14"
                     /label="SCO2780"
                     /locus_tag="SCO2780"
                     /protein_end="319"
                     /protein_start="76"
                     /score="54.0"
                     /tool="antismash"
                     /translation="GVAAALFDYGVEVKGVFGPTTTKDGKPDVQAGDLDVDKVTVLGNE
                     WGKLNVEKYASLAPEVLITTTFDTAGTLWSVPEESKDKVAKLAPSVAISVFDRQLTQPL
                     QRMWELAESLGADMKAKKVTDAKAAFDKAAARLRAAAKAKPEIRVLAGSASPDLFYVSG
                     TNLSVDLEYFKALGVNFVEPSEDAKKATGGWFESLSWENVDKYPADVIIMDDRASTIQP
                     ADITEGTWKQLPAVKAGQVIA"
     regulatory      9527..9530
                     /regulatory_class="ribosome_binding_site"
     gene            9738..10583
                     /db_xref="GeneID:1098215"
                     /gene_synonym="SCC105.12"
                     /locus_tag="SCO2781"
     CDS             9738..10583
                     /codon_start=1
                     /db_xref="GeneID:1098215"
                     /gene_functions="other (smcogs) SMCOG1200:vibriobactin
                     utilization protein ViuB (Score: 242.1; E-value: 9.3e-74)"
                     /gene_kind="other"
                     /gene_synonym="SCC105.12"
                     /locus_tag="SCO2781"
                     /note="SCC105.12, hypothetical protein, len: 281 aa;
                     similar to TR:CAB56689 (EMBL:AL121596) Streptomyces
                     coelicolor hypothetical 28.7 kD protein, 259 aa; fasta
                     scores: opt: 261 z-score: 302.6 E(): 2e-09; 34.9% identity
                     in 255 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_627011.1"
                     /transl_table=11
                     /translation="MRVPDPAPPAGSKRHPPSPALARVTFAGPDLRAFRSDGLDQSLSL
                     FLPHPGQAEPAVPVELGEGWWQGWRELPEDVRAVMRSYTLRSLRRDTDGHTAEIDVDFV
                     LHGLEPDSGIQAGPAARWAADAAPGDRVLLLGPAVADNRAIRFRPPEDTDLVVIWGDET
                     AVPAACAIVEALPAGTRARVWLQVPHAEDVQDLRTAADAEITWLVGDAADGPEATLATL
                     RAAQLPPAEHPYVWIAGESGCVKRLRRHFVGERGVDRRRVTFVGYWRRGLTEEQLREQG
                     "
     PFAM_domain     9777..10157
                     /aSDomain="FAD_binding_9"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08021.14"
                     /description="Siderophore-interacting FAD-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2781_0265"
                     /evalue="6.80E-41"
                     /label="SCO2781"
                     /locus_tag="SCO2781"
                     /protein_end="140"
                     /protein_start="13"
                     /score="139.4"
                     /tool="antismash"
                     /translation="RHPPSPALARVTFAGPDLRAFRSDGLDQSLSLFLPHPGQAEPAVP
                     VELGEGWWQGWRELPEDVRAVMRSYTLRSLRRDTDGHTAEIDVDFVLHGLEPDSGIQAG
                     PAARWAADAAPGDRVLLLGPAVA"
     PFAM_domain     10200..10550
                     /aSDomain="SIP"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04954.16"
                     /description="Siderophore-interacting protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2781_0266"
                     /evalue="6.20E-38"
                     /label="SCO2781"
                     /locus_tag="SCO2781"
                     /protein_end="271"
                     /protein_start="154"
                     /score="130.1"
                     /tool="antismash"
                     /translation="LVVIWGDETAVPAACAIVEALPAGTRARVWLQVPHAEDVQDLRTA
                     ADAEITWLVGDAADGPEATLATLRAAQLPPAEHPYVWIAGESGCVKRLRRHFVGERGVD
                     RRRVTFVGYWRRG"
     misc_feature    10665..10683
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 36.53"
                     /tool="antismash"
     regulatory      10734..10739
                     /regulatory_class="ribosome_binding_site"
     gene            10747..12189
                     /db_xref="GeneID:1098216"
                     /gene_synonym="SCC105.13"
                     /locus_tag="SCO2782"
     CDS             10747..12189
                     /NRPS_PKS="Domain: Aminotran_5 (141-265). E-value: 6.2e-09.
                     Score: 27.0. Matches aSDomain:
                     nrpspksdomains_SCO2782_Aminotran_5.1"
                     /codon_start=1
                     /db_xref="GeneID:1098216"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 381.1;
                     E-value: 1.2e-115)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCC105.13"
                     /locus_tag="SCO2782"
                     /note="SCC105.13, probable pyridoxal-dependent
                     decarboxylase, len: 480 aa; similar to SW:RHSB_RHIME
                     (EMBL:AF110737) Rhizobium meliloti L-2,4-diaminobutyrate
                     decarboxylase (EC 4.1.1.-) RhsB, 495 aa; fasta scores: opt:
                     1111 z-score: 1326.2 E(): 0; 41.9% identity in 458 aa
                     overlap. Contains Pfam match to entry PF00282
                     pyridoxal_deC, Pyridoxal-dependent decarboxylase conserved
                     domain"
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="NP_627012.1"
                     /sec_met_domain="Aminotran_5 (E-value: 8.3e-06, bitscore:
                     23.8, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSHLLNDTTAEQYRRSVTEGVERVAAKLATTDRPFTGVTVDALS
                     PRIDAIDLDEPLHDTAAVLDELEDVYLRDAVYFHHPRYLAHLNCPVVIPALLGEAVLSA
                     VNSSLDTWDQSAGGTLIERKLIDWTCARIGLGPAADGVFTSGGTQSNLQALLLAREEAK
                     AEDFADLRIFASEASHFSVRKSAKLLGLGPDAVVSIPVDRDKRMQTVALARELERCARD
                     GLVPMAVVATGGTTDFGSIDPLPEIAGLCEQYGVWMHVDAAYGCGLLASLKYRDRITGI
                     ERADSVTVDYHKSFFQPVSSSAVLVRDAATLRHATYHAEYLNPRRMVQERIPNQVDKSL
                     QTTRRFDALKLWMTLRVMGADGIGVLFDEVCDLAAEGWKLLAADPRFDVVVQPSLSTLV
                     FRHIPADVTDPAEIDRANLYARKALFASGDAVVAGTKVAGRHYLKFTLLNPETTPADIA
                     AVLDLIAGHAEQYLGDSLDRAS"
     PFAM_domain     10930..11949
                     /aSDomain="Pyridoxal_deC"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00282.22"
                     /db_xref="GO:0016830"
                     /db_xref="GO:0019752"
                     /db_xref="GO:0030170"
                     /description="Pyridoxal-dependent decarboxylase conserved
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2782_0267"
                     /evalue="2.70E-59"
                     /gene_ontologies="GO:0016830: carbon-carbon lyase activity"
                     /gene_ontologies="GO:0019752: carboxylic acid metabolic
                     process"
                     /gene_ontologies="GO:0030170: pyridoxal phosphate binding"
                     /label="SCO2782"
                     /locus_tag="SCO2782"
                     /protein_end="401"
                     /protein_start="61"
                     /score="200.9"
                     /tool="antismash"
                     /translation="AVLDELEDVYLRDAVYFHHPRYLAHLNCPVVIPALLGEAVLSAVN
                     SSLDTWDQSAGGTLIERKLIDWTCARIGLGPAADGVFTSGGTQSNLQALLLAREEAKAE
                     DFADLRIFASEASHFSVRKSAKLLGLGPDAVVSIPVDRDKRMQTVALARELERCARDGL
                     VPMAVVATGGTTDFGSIDPLPEIAGLCEQYGVWMHVDAAYGCGLLASLKYRDRITGIER
                     ADSVTVDYHKSFFQPVSSSAVLVRDAATLRHATYHAEYLNPRRMVQERIPNQVDKSLQT
                     TRRFDALKLWMTLRVMGADGIGVLFDEVCDLAAEGWKLLAADPRFDVVVQPSLSTLVFR
                     "
     misc_feature    11161..11955
                     /gene_synonym="SCC105.13"
                     /locus_tag="SCO2782"
                     /note="Pfam match to entry PF00282 pyridoxal_deC,
                     Pyridoxal-dependent decarboxylase conserved domain, score
                     157.60, E-value 4.6e-45"
     aSDomain        11170..11541
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO2782_Aminotran_5.1"
                     /evalue="6.20E-09"
                     /label="SCO2782_Aminotran_5.1"
                     /locus_tag="SCO2782"
                     /protein_end="265"
                     /protein_start="141"
                     /score="27.0"
                     /tool="antismash"
                     /translation="VFTSGGTQSNLQALLLAREEAKAEDFADLRIFASEASHFSVRKSA
                     KLLGLGPDAVVSIPVDRDKRMQTVALARELERCARDGLVPMAVVATGGTTDFGSIDPLP
                     EIAGLCEQYGVWMHVDAAYG"
     gene            12212..13453
                     /db_xref="GeneID:1098217"
                     /gene_synonym="SCC105.14"
                     /locus_tag="SCO2783"
     CDS             12212..13453
                     /codon_start=1
                     /db_xref="GeneID:1098217"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 419.6;
                     E-value: 2.1e-127)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCC105.14"
                     /locus_tag="SCO2783"
                     /note="SCC105.14, probable monooxygenase, len: 413 aa;
                     similar to SW:RHSE_RHIME (EMBL:AF110737) Rhizobium meliloti
                     rhizobactin siderophore biosynthesis protein RhsE (EC
                     1.-.-.-), 454 aa; fasta scores: opt: 616 z-score: 727.2
                     E(): 0; 42.3% identity in 430 aa overlap and to
                     SW:IUCD_ECOLI (EMBL:M18968) Escherichia coli L-lysine
                     6-monooxygenase (EC 1.13.12.10) IucD, 425 aa; fasta scores:
                     opt: 802 z-score: 946.5 E(): 0; 31.6% identity in 414 aa
                     overlap"
                     /product="monooxygenase"
                     /protein_id="NP_627013.1"
                     /transl_table=11
                     /translation="MGIGLGPFNLGLACLTEPVAELNGVFLESKPDFEWHAGMFLDGAH
                     LQTPFMSDLVTLADPTSPYSFLNYLKEQGRLYSFYIRENFYPLRVEYDDYCRWAARKLS
                     SVRFSTTVTEVTYDEREELYAVATTSGDTYRARRLVLGTGTPPHIPDACRGLAGDFLHN
                     SRYVRHRAELVKKKSITLVGSGQSAAEIYQDLLSEIDVHGYGLNWVTRSPRFFPLEYTK
                     LTLEMTSPEYVDYYHALPEDTRYRLTAEQKGLFKGIDGDLINEIFDLLYQKRLGGPVPT
                     RLLTNSALTSARYADGTYTLGFRQEEQGTDFEIETEGLVLATGYRYTEPEFLKPVRDRL
                     RYDSRGNFDIGRNYAVDVTGGGVFLQNAGVHAHSVTSPDLGMGAYRNSCIVRELLGREY
                     YPVEQSIAFQEFAV"
     PFAM_domain     12215..13189
                     /aSDomain="Lys_Orn_oxgnase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13434.9"
                     /description="L-lysine 6-monooxygenase/L-ornithine
                     5-monooxygenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2783_0268"
                     /evalue="1.20E-120"
                     /label="SCO2783"
                     /locus_tag="SCO2783"
                     /protein_end="326"
                     /protein_start="1"
                     /score="402.9"
                     /tool="antismash"
                     /translation="GIGLGPFNLGLACLTEPVAELNGVFLESKPDFEWHAGMFLDGAHL
                     QTPFMSDLVTLADPTSPYSFLNYLKEQGRLYSFYIRENFYPLRVEYDDYCRWAARKLSS
                     VRFSTTVTEVTYDEREELYAVATTSGDTYRARRLVLGTGTPPHIPDACRGLAGDFLHNS
                     RYVRHRAELVKKKSITLVGSGQSAAEIYQDLLSEIDVHGYGLNWVTRSPRFFPLEYTKL
                     TLEMTSPEYVDYYHALPEDTRYRLTAEQKGLFKGIDGDLINEIFDLLYQKRLGGPVPTR
                     LLTNSALTSARYADGTYTLGFRQEEQGTDFEIETEGLVLATGYR"
     regulatory      13437..13441
                     /gene_synonym="SCC105.14"
                     /locus_tag="SCO2783"
                     /regulatory_class="ribosome_binding_site"
     gene            13450..14004
                     /db_xref="GeneID:1098218"
                     /gene_synonym="SCC105.15"
                     /locus_tag="SCO2784"
     CDS             13450..14004
                     /codon_start=1
                     /db_xref="GeneID:1098218"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     135.3; E-value: 6.2e-41)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCC105.15"
                     /locus_tag="SCO2784"
                     /note="SCC105.15, probable aceytltranferase, len: 184 aa;
                     similar to SW:RHSD_RHIME (EMBL:AF110737) Rhizobium meliloti
                     rhizobactin siderophore biosynthesis protein RhsD, 196 aa;
                     fasta scores: opt: 257 z-score: 326.7 E(): 9.2e-11; 33.7%
                     identity in 172 aa overlap and to TR:AAD46626
                     (EMBL:AF162771) Pseudomonas aeruginosa aminoglycoside
                     6'-N-acetyltransferase Aac, 193 aa; fasta scores: opt: 175
                     z-score: 226.3 E(): 3.6e-05; 28.2% identity in 174 aa
                     overlap"
                     /product="aceytltranferase"
                     /protein_id="NP_627014.1"
                     /transl_table=11
                     /translation="MSRLSTTTPVGALTLRPVDPLTDAVLLHGWLTHPKSAFWMMQDAR
                     LVDVERAYMELAADEHQQAHLGLHDGVPAFLTERYDPAHRELVGLYEPEPGDVGMHFLV
                     APTDRPVHGFTRAVITTVMTELFADPATRRVVVEPDVTNTAVHALNAAVGFVPEREIQK
                     PEKKALLSFCTREQFAKAVSA"
     PFAM_domain     13504..13935
                     /aSDomain="Acetyltransf_8"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13523.9"
                     /description="Acetyltransferase (GNAT) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2784_0269"
                     /evalue="1.50E-48"
                     /label="SCO2784"
                     /locus_tag="SCO2784"
                     /protein_end="162"
                     /protein_start="18"
                     /score="164.2"
                     /tool="antismash"
                     /translation="DPLTDAVLLHGWLTHPKSAFWMMQDARLVDVERAYMELAADEHQQ
                     AHLGLHDGVPAFLTERYDPAHRELVGLYEPEPGDVGMHFLVAPTDRPVHGFTRAVITTV
                     MTELFADPATRRVVVEPDVTNTAVHALNAAVGFVPEREIQ"
     gene            14001..15788
                     /db_xref="GeneID:1098219"
                     /gene_synonym="SCC105.16"
                     /locus_tag="SCO2785"
     CDS             14001..15788
                     /codon_start=1
                     /db_xref="GeneID:1098219"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SCC105.16"
                     /locus_tag="SCO2785"
                     /note="SCC105.16, hypothetical protein, len: 595 aa;
                     similar to SW:RHSF_RHIME (EMBL:AF110737) Rhizobium meliloti
                     rhizobactin siderophore biosynthesis protein RhsF, 601 aa;
                     fasta scores: opt: 1094 z-score: 1325.6 E(): 0; 32.4%
                     identity in 592 aa overlap and to TR:P94255 (EMBL:U61153)
                     Bordetella bronchiseptica AlcC, 618 aa; fasta scores: opt:
                     2037 z-score: 2470.2 E(): 0; 51.5% identity in 592 aa
                     overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_627015.1"
                     /sec_met_domain="IucA_IucC (E-value: 5.4e-78, bitscore:
                     260.8, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLADAVAHLTPERWEEANRLLVRKALAEFTHERLLTPEREPDDG
                     GGQTYVVRSDDGQTAYRFTATVRALDHWQVDAASVTRHRDGAELPLAALDFFIELKQTL
                     GLSDEILPVYLEEISSTLSGTCYKLTKPQLSSAELARSGDFQAVETGMTEGHPCFVANN
                     GRLGFGIHEYLSYAPETASPVRLVWLAAHRSRAAFTAGVGIEYESFVRDELGAATVDRF
                     HGVLRGRGLDPADYLLIPVHPWQWWNKLTVTFAAEVARGHLVCLGEGDDEYLAQQSIRT
                     FFNASHPGKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLARLIEGDPVLKETGLSI
                     IRERAAVGYRHLEYEQATDRYSPYRKMLAALWRESPVPSIREGETLATMASLVHQDHEG
                     ASFAGALIERSGLTPTEWLRHYLRAYYVPLLHSFYAYDLVYMPHGENVILVLADGVVRR
                     AVYKDIAEEIAVMDPDAVLPPEVSRIAVDVPDDKKLLSIFTDVFDCFFRFLAANLAEEG
                     IVTEDAFWRTVAEVTREYQESVPELADKFERYDMFAPEFALSCLNRLQLRDNRQMVDLA
                     DPSGALQLVGTLKNPLAGR"
     PFAM_domain     14430..15182
                     /aSDomain="IucA_IucC"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04183.15"
                     /db_xref="GO:0019290"
                     /description="IucA / IucC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2785_0270"
                     /evalue="2.10E-77"
                     /gene_ontologies="GO:0019290: siderophore biosynthetic
                     process"
                     /label="SCO2785"
                     /locus_tag="SCO2785"
                     /protein_end="394"
                     /protein_start="143"
                     /score="260.1"
                     /tool="antismash"
                     /translation="DFQAVETGMTEGHPCFVANNGRLGFGIHEYLSYAPETASPVRLVW
                     LAAHRSRAAFTAGVGIEYESFVRDELGAATVDRFHGVLRGRGLDPADYLLIPVHPWQWW
                     NKLTVTFAAEVARGHLVCLGEGDDEYLAQQSIRTFFNASHPGKHYVKTALSVLNMGFMR
                     GLSAAYMEATPAINDWLARLIEGDPVLKETGLSIIRERAAVGYRHLEYEQATDRYSPYR
                     KMLAALWRESPVPSIREGETLATMASLVH"
     PFAM_domain     15246..15716
                     /aSDomain="FhuF"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF06276.15"
                     /description="Ferric iron reductase FhuF-like transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2785_0271"
                     /evalue="2.50E-39"
                     /label="SCO2785"
                     /locus_tag="SCO2785"
                     /protein_end="572"
                     /protein_start="415"
                     /score="135.4"
                     /tool="antismash"
                     /translation="EWLRHYLRAYYVPLLHSFYAYDLVYMPHGENVILVLADGVVRRAV
                     YKDIAEEIAVMDPDAVLPPEVSRIAVDVPDDKKLLSIFTDVFDCFFRFLAANLAEEGIV
                     TEDAFWRTVAEVTREYQESVPELADKFERYDMFAPEFALSCLNRLQLRDNRQM"
     gene            complement(15858..17465)
                     /db_xref="GeneID:1098220"
                     /gene_synonym="hexA; SCC105.17c"
                     /locus_tag="SCO2786"
     CDS             complement(15858..17465)
                     /codon_start=1
                     /db_xref="GeneID:1098220"
                     /gene_synonym="hexA; SCC105.17c"
                     /locus_tag="SCO2786"
                     /note="SCC105.17c, hexA, beta-N-acetylhexosaminidase
                     precursor, len: 535 aa; highly similar to TR:O85361
                     (EMBL:AF063001) Streptomyces plicatus
                     B-N-acetylhexosaminidase, Hex, 561 aa; fasta scores: opt:
                     2991 z-score: 3318.1 E(): 0; 93.2% identity in 469 aa
                     overlap and to TR:BAA8876 (EMBL:AB015350) Streptomyces
                     thermoviolaceus beta-N-acetylglucosaminidase precursor
                     NagB, 541 aa; fasta scores: opt: 2856 z-score: 3168.6 E():
                     0; 76.7% identity in 537 aa overlap. Contains Pfam match to
                     entry PF00728 Glyco_hydro_20, Glycosyl hydrolase family 20
                     and possible N-terminal region signal peptide sequence"
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="NP_627016.1"
                     /transl_table=11
                     /translation="MRPHRRHHRTTPRITRLLGSLLLVAAVGAMTTGAAPVRKAAAEPT
                     PLDRVIPAPASVEPGGAPYRITRGTHIRVDDSREARRVGDYLADLLRPATGYRLPVTSH
                     GHGGIRLRLAEGPYGDEGYRLDSGREGVTITARKAAGLFHGVQTLRQLLPAAVEKDSAQ
                     PGPWLVAGGTIEDTPRYAWRSAMLDVSRHFFSVDEVKRYIDRVALYKYNKLHLHISDDQ
                     GWRLAIDSWPRLATYGGSTEVGGGPGGHYTKADYEEIVRYAASRHLEVVPEIDMPGHTN
                     AALASYAELNCDGVAPPLYTGTKVGFSTLCVDKDVTYDFVDDVLGELAALTPGRYLHIG
                     GDEAHSTPQADFVAFMKRVQPIVAKYGKTVVGWHQLAGAEPVEGALVQYWGLDRTSDAE
                     KAQVAAAARNGTGLILSPADRTYLDMKYTKDTPLGLSWAGYVEVRRSYDWDPAAYLPGA
                     PAEAVRGVEAPLWTETLSDPDQLDFMAFPRLPGVAELGWSPASTHDWDTYKVRLAGQAP
                     HWEAMGIDYYRSPQVPWT"
     PFAM_domain     complement(15969..16409)
                     /aSDomain="Glyco_hydro_20"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00728.25"
                     /db_xref="GO:0004553"
                     /db_xref="GO:0005975"
                     /description="Glycosyl hydrolase family 20, catalytic
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2786_0274"
                     /evalue="2.10E-23"
                     /gene_ontologies="GO:0004553: hydrolase activity,
                     hydrolyzing O-glycosyl compounds"
                     /gene_ontologies="GO:0005975: carbohydrate metabolic
                     process"
                     /label="SCO2786"
                     /locus_tag="SCO2786"
                     /protein_end="499"
                     /protein_start="352"
                     /score="83.3"
                     /tool="antismash"
                     /translation="VAFMKRVQPIVAKYGKTVVGWHQLAGAEPVEGALVQYWGLDRTSD
                     AEKAQVAAAARNGTGLILSPADRTYLDMKYTKDTPLGLSWAGYVEVRRSYDWDPAAYLP
                     GAPAEAVRGVEAPLWTETLSDPDQLDFMAFPRLPGVAELGWSP"
     PFAM_domain     complement(16428..16928)
                     /aSDomain="Glyco_hydro_20"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00728.25"
                     /db_xref="GO:0004553"
                     /db_xref="GO:0005975"
                     /description="Glycosyl hydrolase family 20, catalytic
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2786_0273"
                     /evalue="3.60E-56"
                     /gene_ontologies="GO:0004553: hydrolase activity,
                     hydrolyzing O-glycosyl compounds"
                     /gene_ontologies="GO:0005975: carbohydrate metabolic
                     process"
                     /label="SCO2786"
                     /locus_tag="SCO2786"
                     /protein_end="346"
                     /protein_start="179"
                     /score="191.1"
                     /tool="antismash"
                     /translation="YAWRSAMLDVSRHFFSVDEVKRYIDRVALYKYNKLHLHISDDQGW
                     RLAIDSWPRLATYGGSTEVGGGPGGHYTKADYEEIVRYAASRHLEVVPEIDMPGHTNAA
                     LASYAELNCDGVAPPLYTGTKVGFSTLCVDKDVTYDFVDDVLGELAALTPGRYLHIGGD
                     EAHS"
     misc_feature    complement(16608..17108)
                     /gene_synonym="hexA; SCC105.17c"
                     /locus_tag="SCO2786"
                     /note="Pfam match to entry PF00728 Glyco_hydro_20, Glycosyl
                     hydrolase family 20, score 142.50, E-value 7.3e-39"
     PFAM_domain     complement(16938..17321)
                     /aSDomain="Glyco_hydro_20b"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02838.18"
                     /description="Glycosyl hydrolase family 20, domain 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2786_0272"
                     /evalue="1.00E-23"
                     /label="SCO2786"
                     /locus_tag="SCO2786"
                     /protein_end="176"
                     /protein_start="48"
                     /score="84.6"
                     /tool="antismash"
                     /translation="RVIPAPASVEPGGAPYRITRGTHIRVDDSREARRVGDYLADLLRP
                     ATGYRLPVTSHGHGGIRLRLAEGPYGDEGYRLDSGREGVTITARKAAGLFHGVQTLRQL
                     LPAAVEKDSAQPGPWLVAGGTIED"
     regulatory      complement(17471..17476)
                     /regulatory_class="ribosome_binding_site"
     gene            17580..18476
                     /db_xref="GeneID:1098221"
                     /gene_synonym="SCC105.18"
                     /locus_tag="SCO2787"
     CDS             17580..18476
                     /codon_start=1
                     /db_xref="GeneID:1098221"
                     /gene_synonym="SCC105.18"
                     /locus_tag="SCO2787"
                     /note="SCC105.18, hypothetical protein, len: 298 aa;
                     similar to TR:Q9RDQ8 (EMBL:AL133423) Streptomyces
                     coelicolor hypothetical 31.7 kD protein SC4A7.04, 295 aa;
                     fasta scores: opt: 556 z-score: 623.0 E(): 2.9e-27; 37.4%
                     identity in 294 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_627017.1"
                     /transl_table=11
                     /translation="MAEIIQKDGTWVFDGDALRLTPGRDKNVSLLRRELGELLVPLAAL
                     AGISFEQGKKSGRLRLRLRDGADPLLHAAGGRLTEPHDPYQLLVESDRYGVAEYFVDEV
                     RNALLLDQVPSGPVDAYLLPGPSVPLSVSAGDGVASFDGERVRLEWKWQAEDAKSAAGP
                     RTLPLADIVAVEWQPTIGLENGHLRFTVRAAPSKVPPKYDPNAVELWGFKKDPLMALVA
                     AAVQARLPHPAARAALEDARAGEDTSTPATAPPAPAAEDDHDALLRRLRELGDLHRSGV
                     LTDEEFALAKQAVLKRM"
     PFAM_domain     17610..17894
                     /aSDomain="DUF4429"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF14472.9"
                     /description="Domain of unknown function (DUF4429)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2787_0275"
                     /evalue="3.90E-21"
                     /label="SCO2787"
                     /locus_tag="SCO2787"
                     /protein_end="105"
                     /protein_start="10"
                     /score="75.6"
                     /tool="antismash"
                     /translation="WVFDGDALRLTPGRDKNVSLLRRELGELLVPLAALAGISFEQGKK
                     SGRLRLRLRDGADPLLHAAGGRLTEPHDPYQLLVESDRYGVAEYFVDEVR"
     PFAM_domain     17994..18254
                     /aSDomain="DUF4429"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF14472.9"
                     /description="Domain of unknown function (DUF4429)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2787_0276"
                     /evalue="1.30E-24"
                     /label="SCO2787"
                     /locus_tag="SCO2787"
                     /protein_end="225"
                     /protein_start="138"
                     /score="86.7"
                     /tool="antismash"
                     /translation="ASFDGERVRLEWKWQAEDAKSAAGPRTLPLADIVAVEWQPTIGLE
                     NGHLRFTVRAAPSKVPPKYDPNAVELWGFKKDPLMALVAAAV"
     gene            18565..18822
                     /db_xref="GeneID:1098222"
                     /gene_synonym="SCC105.19"
                     /locus_tag="SCO2788"
     CDS             18565..18822
                     /codon_start=1
                     /db_xref="GeneID:1098222"
                     /gene_synonym="SCC105.19"
                     /locus_tag="SCO2788"
                     /note="SCC105.19, unknown, len: 85 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_627018.1"
                     /transl_table=11
                     /translation="MHDELVDHLTRSTPLSRGEALRVVQDVLAYFDETTEEYVRRRHRE
                     LQAQGLVNATIFERIEAELKYRAVAPPELSLRQLRRIVYG"
     gene            18892..20709
                     /db_xref="GeneID:1098223"
                     /gene_synonym="glmS2; SCC105.20"
                     /locus_tag="SCO2789"
     CDS             18892..20709
                     /codon_start=1
                     /db_xref="GeneID:1098223"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="glmS2; SCC105.20"
                     /locus_tag="SCO2789"
                     /note="SCC105.20, glmS2, glucosamine-fructose-6-phosphate
                     aminotransferase, len: 605 aa; similar to SW:GLMS_ECOLI
                     (EMBL:X01631) Escherichia coli
                     glucosamine-fructose-6-phosphate aminotransferase
                     [isomerizing] (EC 2.6.1.16) GlmS, 608 aa; fasta scores:
                     opt: 1617 z-score: 1815.6 E(): 0; 44.1% identity in 612 aa
                     overlap and highly similar to TR:BAA86263 (EMBL:AB023785)
                     Streptomyces griseus ORF3 (fragment), 589 aa; fasta scores:
                     opt: 3364 z-score: 3776.2 E(): 0; 87.6% identity in 589 aa
                     overlap and also to SW:GLMS_STRCO (EMBL:AL031317)
                     Streptomyces coelicolor GlmS1, probable
                     glucosamine--fructose-6-phosphate aminotransferase
                     SC6G4.18, 615 aa; fasta scores: opt: 1480 z-score: 1526.7
                     E(): 0; 43.8% identity in 621 aa overlap. Contains Pfam
                     matches to entries PF00310 GATase_2, Glutamine
                     amidotransferases class-II and 2x PF01380 SIS, SIS domain"
                     /product="glucosamine-fructose-6-phosphate
                     aminotransferase"
                     /protein_id="NP_627019.1"
                     /sec_met_domain="GATase_7 (E-value: 2.2e-16, bitscore:
                     58.7, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGKRDVAPLLLEGLQRLEYRGYDSAGIVVTSPKAAGLR
                     MVKAKGRVRDLEAKVPARFKGTTGIAHTRWATHGAPSDVNAHPHMSADNKVAVVHNGII
                     DNAADLRRKLEADGVEFLSETDTEVLVHLIARSEAEKLEDKVRETLRVIEGTYGIAVMH
                     ADFPERIVVARNGSPVVLGIGEKEMFVASDIAALVAHTRQIVTLDDGEMATLKADDFRT
                     YTTEGTRTTSEPTTVEWEAASYDMGGHDTYMHKEIHEQAEAVDRVLRGRIDDRFSTVHL
                     GGLNLDARDARAVRRVKILGCGTSYHAGQIGAQMIEELARIPADAEPASEFRYRNAVVD
                     PDTLYIAVSQSGETYDVLAAVQELKRKGARVLGIVNVVGSAIAREADGGMYVHAGPEVC
                     VVSTKCFTNTCVAFALLALHLGRTRDLSVRDGKRIIEGLRKLPAQIEEMLKQEEDVKKL
                     AAQYAEARSMLFIGRVRGYPVAREASLKLKEVSYIHAEAYPASELKHGPLALIEPALPT
                     VAIVPDDDLLEKNRAALEEIKARSGQILAVAHQEQEKADHTIVVPKNEDELDPILMGIP
                     LQLLAYHTALALGRDIDKPRNLAKSVTVE"
     misc_feature    18895..19437
                     /gene_synonym="glmS2; SCC105.20"
                     /locus_tag="SCO2789"
                     /note="Pfam match to entry PF00310 GATase_2, Glutamine
                     amidotransferases class-II, score 264.50, E-value 1.3e-89"
     aSDomain        18895..20706
                     /aSDomain="TIGR01135"
                     /aSTool="tigrfam"
                     /description="glmS: glutamine-fructose-6-phosphate
                     transaminase (isomerizing)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO2789_0025"
                     /evalue="2.00E-226"
                     /identifier="TIGR01135"
                     /label="SCO2789"
                     /locus_tag="SCO2789"
                     /protein_end="605"
                     /protein_start="1"
                     /score="751.1"
                     /tool="antismash"
                     /translation="CGIVGYIGKRDVAPLLLEGLQRLEYRGYDSAGIVVTSPKAAGLRM
                     VKAKGRVRDLEAKVPARFKGTTGIAHTRWATHGAPSDVNAHPHMSADNKVAVVHNGIID
                     NAADLRRKLEADGVEFLSETDTEVLVHLIARSEAEKLEDKVRETLRVIEGTYGIAVMHA
                     DFPERIVVARNGSPVVLGIGEKEMFVASDIAALVAHTRQIVTLDDGEMATLKADDFRTY
                     TTEGTRTTSEPTTVEWEAASYDMGGHDTYMHKEIHEQAEAVDRVLRGRIDDRFSTVHLG
                     GLNLDARDARAVRRVKILGCGTSYHAGQIGAQMIEELARIPADAEPASEFRYRNAVVDP
                     DTLYIAVSQSGETYDVLAAVQELKRKGARVLGIVNVVGSAIAREADGGMYVHAGPEVCV
                     VSTKCFTNTCVAFALLALHLGRTRDLSVRDGKRIIEGLRKLPAQIEEMLKQEEDVKKLA
                     AQYAEARSMLFIGRVRGYPVAREASLKLKEVSYIHAEAYPASELKHGPLALIEPALPTV
                     AIVPDDDLLEKNRAALEEIKARSGQILAVAHQEQEKADHTIVVPKNEDELDPILMGIPL
                     QLLAYHTALALGRDIDKPRNLAKSVTVE"
     PFAM_domain     19081..19470
                     /aSDomain="GATase_6"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13522.9"
                     /description="Glutamine amidotransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2789_0277"
                     /evalue="2.10E-20"
                     /label="SCO2789"
                     /locus_tag="SCO2789"
                     /protein_end="193"
                     /protein_start="63"
                     /score="73.3"
                     /tool="antismash"
                     /translation="FKGTTGIAHTRWATHGAPSDVNAHPHMSADNKVAVVHNGIIDNAA
                     DLRRKLEADGVEFLSETDTEVLVHLIARSEAEKLEDKVRETLRVIEGTYGIAVMHADFP
                     ERIVVARNGSPVVLGIGEKEMFVASD"
     misc_feature    19753..20157
                     /gene_synonym="glmS2; SCC105.20"
                     /locus_tag="SCO2789"
                     /note="Pfam match to entry PF01380 SIS, SIS domain, score
                     147.70, E-value 2e-40"
     PFAM_domain     19774..20142
                     /aSDomain="SIS"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01380.25"
                     /db_xref="GO:0097367"
                     /db_xref="GO:1901135"
                     /description="SIS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2789_0278"
                     /evalue="1.10E-30"
                     /gene_ontologies="GO:0097367: carbohydrate derivative
                     binding"
                     /gene_ontologies="GO:1901135: carbohydrate derivative
                     metabolic process"
                     /label="SCO2789"
                     /locus_tag="SCO2789"
                     /protein_end="417"
                     /protein_start="294"
                     /score="106.2"
                     /tool="antismash"
                     /translation="RRVKILGCGTSYHAGQIGAQMIEELARIPADAEPASEFRYRNAVV
                     DPDTLYIAVSQSGETYDVLAAVQELKRKGARVLGIVNVVGSAIAREADGGMYVHAGPEV
                     CVVSTKCFTNTCVAFALLA"
     misc_feature    20266..20664
                     /gene_synonym="glmS2; SCC105.20"
                     /locus_tag="SCO2789"
                     /note="Pfam match to entry PF01380 SIS, SIS domain, score
                     88.50, E-value 1.3e-22"
     PFAM_domain     20275..20649
                     /aSDomain="SIS"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01380.25"
                     /db_xref="GO:0097367"
                     /db_xref="GO:1901135"
                     /description="SIS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2789_0279"
                     /evalue="6.30E-19"
                     /gene_ontologies="GO:0097367: carbohydrate derivative
                     binding"
                     /gene_ontologies="GO:1901135: carbohydrate derivative
                     metabolic process"
                     /label="SCO2789"
                     /locus_tag="SCO2789"
                     /protein_end="586"
                     /protein_start="461"
                     /score="68.2"
                     /tool="antismash"
                     /translation="YAEARSMLFIGRVRGYPVAREASLKLKEVSYIHAEAYPASELKHG
                     PLALIEPALPTVAIVPDDDLLEKNRAALEEIKARSGQILAVAHQEQEKADHTIVVPKNE
                     DELDPILMGIPLQLLAYHTAL"
     gene            complement(20725..21252)
                     /db_xref="GeneID:1098224"
                     /gene_synonym="SCC105.21c"
                     /locus_tag="SCO2790"
     CDS             complement(20725..21252)
                     /codon_start=1
                     /db_xref="GeneID:1098224"
                     /gene_synonym="SCC105.21c"
                     /locus_tag="SCO2790"
                     /note="SCC105.21c, hypothetical protein, len: 175 aa;
                     highly similar to TR:BAA86264 (EMBL:AB023785) Streptomyces
                     griseus ORF2, 173 aa; fasta scores: opt: 998 z-score:
                     1157.6 E(): 0; 82.9% identity in 175 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_627020.1"
                     /transl_table=11
                     /translation="MAGHEFFEPADRKRPVAEPTAAEPLAAEEPRQSCDPAFKHGVVVG
                     FDGSTSSERALAYAIGMASRLGSGLVIVHVANRLPTTVWAGCEPPVFVDVPDHRTEVLG
                     LELACADYLAEVSWILVERGGDICHELEEVGREYEADAIVVGSSHGLVGRLFGSVAGRL
                     AKRAKRPVVVIP"
     PFAM_domain     complement(20728..21129)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2790_0280"
                     /evalue="7.30E-19"
                     /label="SCO2790"
                     /locus_tag="SCO2790"
                     /protein_end="175"
                     /protein_start="41"
                     /score="68.8"
                     /tool="antismash"
                     /translation="VVVGFDGSTSSERALAYAIGMASRLGSGLVIVHVANRLPTTVWAG
                     CEPPVFVDVPDHRTEVLGLELACADYLAEVSWILVERGGDICHELEEVGREYEADAIVV
                     GSSHGLVGRLFGSVAGRLAKRAKRPVVVIP"
     gene            complement(21558..21869)
                     /db_xref="GeneID:1098225"
                     /gene_synonym="SCC105.22c"
                     /locus_tag="SCO2791"
     CDS             complement(21558..21869)
                     /codon_start=1
                     /db_xref="GeneID:1098225"
                     /gene_synonym="SCC105.22c"
                     /locus_tag="SCO2791"
                     /note="SCC105.22c, unknown, len: 103 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_627021.1"
                     /transl_table=11
                     /translation="MRGNRSVDRCFFPSVPPAPACLPPTSARPLPGRDPLGTPQQQTAR
                     GGDGGQAEGRAGGAREGGAVPEERHRDEEAAERRPADEIGDAVPVGCAGRRVGGTVRS"
     misc_feature    22032..22045
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.26"
                     /tool="antismash"
     gene            22241..23437
                     /db_xref="GeneID:1098226"
                     /gene_synonym="adpA; SCC105.23"
                     /locus_tag="SCO2792"
     CDS             22241..23437
                     /codon_start=1
                     /db_xref="GeneID:1098226"
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 89.3; E-value: 4.1e-27)"
                     /gene_kind="regulatory"
                     /gene_synonym="adpA; SCC105.23"
                     /locus_tag="SCO2792"
                     /note="SCC105.23, adpA, araC-family transcriptional
                     regulator, len: 398 aa; highly similar to TR:BAA86265
                     (EMBL:AB023785) Streptomyces griseus AdpA, 405 aa; fasta
                     scores: opt: 2219 z-score: 2270.5 E(): 0; 84.4% identity in
                     410 aa overlap and to TR:Q9XA73 (EMBL:AL096822)
                     Streptomyces coelicolor araC-family transcriptional
                     regulator SCGD3.05, 334 aa; fasta scores: opt: 878 z-score:
                     904.2 E(): 0; 45.7% identity in 313 aa overlap. Contains
                     Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory
                     helix-turn-helix proteins, araC family and match to Prosite
                     entry PS00041 Bacterial regulatory proteins, araC family
                     signature. Contains possible helix-turn-helix motif"
                     /product="AraC family transcription regulator"
                     /protein_id="NP_627022.1"
                     /transl_table=11
                     /translation="MSHDSTAAPEAAARKLSGRRRKEIVAVLLFSGGPIFESSIPLSVF
                     GIDRQDAGVPRYRLLVCAGEDGPLRTTGGLELTAPQGLEAISRAGTVVVPAWRSITSPP
                     PEEALDALRRAHEEGARIVGLCTGAFVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVD
                     PRELFVDDGDVLTSAGTAAGIDLCLHIVRTDHGNEAAGALARRLVVPPRRSGGQERYLD
                     RSLPEEIGADPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQWL
                     ITQRVLQAQRLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGSSPAAYRAAYRARRPQ
                     GDRQPDPDTAAAGATRPLPPSDPPASLAPENAVPFQTRRTATPMPAGAASVPGQRSAP"
     PFAM_domain     22316..22816
                     /aSDomain="DJ-1_PfpI"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01965.27"
                     /description="DJ-1/PfpI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2792_0281"
                     /evalue="6.20E-15"
                     /label="SCO2792"
                     /locus_tag="SCO2792"
                     /protein_end="192"
                     /protein_start="25"
                     /score="55.5"
                     /tool="antismash"
                     /translation="AVLLFSGGPIFESSIPLSVFGIDRQDAGVPRYRLLVCAGEDGPLR
                     TTGGLELTAPQGLEAISRAGTVVVPAWRSITSPPPEEALDALRRAHEEGARIVGLCTGA
                     FVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVDPRELFVDDGDVLTSAGTAAGIDLCL
                     HIVR"
     misc_feature    22913..22915
                     /gene_synonym="adpA; SCC105.23"
                     /locus_tag="SCO2792"
                     /note="TTA Leucine codon. Possible target for bldA
                     regulation"
     misc_feature    22913..22915
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    22982..23242
                     /gene_synonym="adpA; SCC105.23"
                     /locus_tag="SCO2792"
                     /note="Pfam match to entry PF00165 HTH_AraC, Bacterial
                     regulatory helix-turn-helix proteins, araC family, score
                     75.80, E-value 8.8e-19"
     PFAM_domain     23000..23236
                     /aSDomain="HTH_18"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF12833.10"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /db_xref="GO:0043565"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2792_0282"
                     /evalue="7.80E-20"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /gene_ontologies="GO:0043565: sequence-specific DNA
                     binding"
                     /label="SCO2792"
                     /locus_tag="SCO2792"
                     /protein_end="332"
                     /protein_start="253"
                     /score="71.1"
                     /tool="antismash"
                     /translation="LAARAYMSRRTFDRRFRSLTGSAPLQWLITQRVLQAQRLLETSDY
                     SVDEVAGRCGFRSPVALRGHFRRQLGSSPAAYRA"
     misc_feature    23093..23221
                     /gene_synonym="adpA; SCC105.23"
                     /locus_tag="SCO2792"
                     /note="PS00041 Bacterial regulatory proteins, araC family
                     signature"
     stem_loop       23458..23538
                     /note="26633 GAACGCCGGACGGGCCGGAGCGTG-CCCGTCCGGC
                     26666-26680 GCCGGGCGGGGCACACTCAG-CCCGTCCGGCGTTC 26713.
                     Score 54: 30/33 (90%) matches, 2 gaps"
     misc_feature    23669..25526
                     /note="previously sequenced DNA fragment. EMBL:AB036424
                     Streptomyces coelicolor A3(2) adpA, ornA, orf5-h genes for
                     AdpA homolog, oligoribonuclease, transcriptional regulator,
                     partial and complete cds."
     gene            23779..24381
                     /db_xref="GeneID:1098227"
                     /gene_synonym="2SCC13.01; ornA"
                     /locus_tag="SCO2793"
     CDS             23779..24381
                     /codon_start=1
                     /db_xref="GeneID:1098227"
                     /gene_synonym="2SCC13.01; ornA"
                     /locus_tag="SCO2793"
                     /note="3'-5' exoribonuclease specific for small
                     oligoribonuclotides"
                     /product="oligoribonuclease"
                     /protein_id="NP_627023.1"
                     /transl_table=11
                     /translation="MNDRMVWIDCEMTGLSLSDDALIEVAALVTDSELNILGEGVDIVI
                     RPPERALETMPEVVREMHTASGLLAELDGGTTLADAEAQVLAYVREHVKEPGKAPLCGN
                     SVGTDRGFLLRDMATLEGYLHYRIVDVSSIKELARRWYPRAYFNSPEKNGNHRALADIR
                     ESIAELRYYREAVFVPQPGPDSDTARAIAAKHVVSAG"
     misc_feature    23791..24309
                     /gene_synonym="2SCC13.01; ornA"
                     /locus_tag="SCO2793"
                     /note="Pfam match to entry PF00929 Exonuclease,
                     Exonuclease, score 76.80, E-value 4.6e-19"
     PFAM_domain     23794..24282
                     /aSDomain="RNase_T"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00929.27"
                     /description="Exonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2793_0283"
                     /evalue="5.80E-25"
                     /label="SCO2793"
                     /locus_tag="SCO2793"
                     /protein_end="168"
                     /protein_start="5"
                     /score="88.9"
                     /tool="antismash"
                     /translation="VWIDCEMTGLSLSDDALIEVAALVTDSELNILGEGVDIVIRPPER
                     ALETMPEVVREMHTASGLLAELDGGTTLADAEAQVLAYVREHVKEPGKAPLCGNSVGTD
                     RGFLLRDMATLEGYLHYRIVDVSSIKELARRWYPRAYFNSPEKNGNHRALADIRESIAE
                     "
     gene            24503..24575
                     /db_xref="GeneID:3240019"
                     /locus_tag="SCOt19"
     tRNA            24503..24575
                     /db_xref="GeneID:3240019"
                     /locus_tag="SCOt19"
                     /note="tRNA His anticodon GTG, Cove score 71.04"
                     /product="tRNA-His"
     stem_loop       24582..24619
                     /note="possible stem loop. Score 57: 18/18 (100%) matches,
                     0 gaps"
     gene            complement(24943..25998)
                     /db_xref="GeneID:1098228"
                     /gene_synonym="2SCC13.02c"
                     /locus_tag="SCO2794"
     CDS             complement(24943..25998)
                     /codon_start=1
                     /db_xref="GeneID:1098228"
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 356.5; E-value: 2.4e-108)"
                     /gene_kind="regulatory"
                     /gene_synonym="2SCC13.02c"
                     /locus_tag="SCO2794"
                     /note="2SCC13.02c, lacI-family transcriptional regulatory
                     protein, len: 351 aa; highly similar to TR:Q9X9R3
                     (EMBL:AJ009798) Streptomyces reticuli CebR protein, 350 aa;
                     fasta scores: opt: 2011 z-score: 2174.4 E(): 0; 89.4%
                     identity in 350 aa overlap and C-terminal region identical
                     to TR:BAB03462 (EMBL:AB036424) Streptomyces coelicolor
                     transcriptional regulator (fragment) ORF5-H, 193 aa.
                     Contains Pfam matches to entries PF00356 lacI, Bacterial
                     regulatory proteins, lacI family and PF00532
                     Peripla_BP_like, Periplasmic binding proteins and sugar
                     binding domain of the LacI family and match to Prosite
                     entry PS00356 Bacterial regulatory proteins, lacI family
                     signature. Also contains a possible helix-turn-helix motif
                     at residues 14..35 (+6.05 SD)"
                     /product="LacI family transcriptional regulator"
                     /protein_id="NP_627024.1"
                     /transl_table=11
                     /translation="MASHGVRGRSGGRPTLEEVAARAGVGRGTVSRVINGSPRVSDATR
                     AAVEAAVAELGYVPNTAARALAANRTDAIALVVPEPETRFFAEPYFSDMLKGVGSELSE
                     TEMQLLLIFAGSDRERERLAQYLAAHRVDGVLLVSVHADDPLPDLLTQLEIPAVISGPR
                     SAAEPLASVDSDNYGGARSAVEHLLSRGRGRVAHITGHLAVYGAQRRVDGYRDALREAG
                     HEVDEGLIEPGDFTEEGGRRAMAELLRRHPDVDAVFAASDVTAAGAGQVLREAGRRIPD
                     DVALVGYDDSAIARHMEPPLTSVRQPIEEMGRAMIDLLLTEIADRRPAASRGLERHQVV
                     LATELVERRSS"
     PFAM_domain     complement(25024..25785)
                     /aSDomain="Peripla_BP_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00532.24"
                     /description="Periplasmic binding proteins and sugar
                     binding domain of LacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2794_0285"
                     /evalue="2.40E-35"
                     /label="SCO2794"
                     /locus_tag="SCO2794"
                     /protein_end="325"
                     /protein_start="71"
                     /score="122.4"
                     /tool="antismash"
                     /translation="DAIALVVPEPETRFFAEPYFSDMLKGVGSELSETEMQLLLIFAGS
                     DRERERLAQYLAAHRVDGVLLVSVHADDPLPDLLTQLEIPAVISGPRSAAEPLASVDSD
                     NYGGARSAVEHLLSRGRGRVAHITGHLAVYGAQRRVDGYRDALREAGHEVDEGLIEPGD
                     FTEEGGRRAMAELLRRHPDVDAVFAASDVTAAGAGQVLREAGRRIPDDVALVGYDDSAI
                     ARHMEPPLTSVRQPIEEMGRAMIDLLLTEIAD"
     misc_feature    complement(25054..25791)
                     /gene_synonym="2SCC13.02c"
                     /locus_tag="SCO2794"
                     /note="Pfam match to entry PF00532 Peripla_BP_like,
                     Periplasmic binding proteins and sugar binding domain of
                     the LacI family., score 159.90, E-value 4.3e-44"
     PFAM_domain     complement(25819..25956)
                     /aSDomain="LacI"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00356.24"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory proteins, lacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2794_0284"
                     /evalue="5.30E-18"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO2794"
                     /locus_tag="SCO2794"
                     /protein_end="60"
                     /protein_start="14"
                     /score="64.7"
                     /tool="antismash"
                     /translation="TLEEVAARAGVGRGTVSRVINGSPRVSDATRAAVEAAVAELGYVP
                     N"
     misc_feature    complement(25882..25965)
                     /gene_synonym="2SCC13.02c"
                     /locus_tag="SCO2794"
                     /note="Pfam match to entry PF00356 lacI, Bacterial
                     regulatory proteins, lacI family, score 35.50, E-value
                     1.5e-08"
     misc_feature    complement(25897..25953)
                     /gene_synonym="2SCC13.02c"
                     /locus_tag="SCO2794"
                     /note="PS00356 Bacterial regulatory proteins, lacI family
                     signature"
     regulatory      complement(26002..26005)
                     /regulatory_class="ribosome_binding_site"
     misc_feature    26144..26155
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(26219..26233)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     misc_feature    26220..26234
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     regulatory      26353..26358
                     /regulatory_class="ribosome_binding_site"
     gene            26364..27689
                     /db_xref="GeneID:1098229"
                     /gene_synonym="2SCC13.03"
                     /locus_tag="SCO2795"
     CDS             26364..27689
                     /codon_start=1
                     /db_xref="GeneID:1098229"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143:sugar-binding lipoprotein (Score: 199.4; E-value:
                     2e-60)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="2SCC13.03"
                     /locus_tag="SCO2795"
                     /note="2SCC13.03, probable sugar binding hypothetical
                     protein, len: 441 aa; highly similar to TR:Q9X9R7
                     (EMBL:AJ009797) Streptomyces reticuli Cbp protein precursor
                     (fragment) CebE, 444 aa; fasta scores: opt: 1490 z-score:
                     1672.5 E(): 0; 51.2% identity in 445 aa overlap and similar
                     to SW:LACE_AGRRD (EMBL:X66596) Agrobacterium radiobacter
                     Lactose-binding protein precursor LacE, 422 aa; fasta
                     scores: opt: 263 z-score: 298.4 E(): 4.1e-09; 23.1%
                     identity in 398 aa overlap. Contains Pfam match to entry
                     PF01547 SBP_bacterial_1, Bacterial extracellular
                     solute-binding protein and correctly situated match to
                     Prosite entry PS00013 Prokaryotic membrane lipoprotein
                     lipid attachment site. Also contains possible N-terminal
                     region signal peptide sequence"
                     /product="sugar binding hypothetical protein"
                     /protein_id="NP_627025.1"
                     /transl_table=11
                     /translation="MRAARRGSARRVVVMAAIASLGAGLLAGCADDGNDEDSSSSGDSS
                     GKTTITLGLFGTMGFKEAGLYDEYEKLNPDINIEENVTERNENYYPALVNHLTTNSGLQ
                     DVQAIEVGNIAEVVATQADKFEDMSKAAGVQKANWLDWKWQQATTKDGATIGLGTDIGP
                     MAICYRKDLFEKAGLPTDREEVSKLWAGDWNKFIEAGEKYKKGAGKDTYFMDSPGGLIN
                     AILSSEDEKFYDASGKVIYKTNPAVKDAFDLTAEAAEKGLVQSQTQFQPAWDQTISNSL
                     FATVACPPWMLGTIKAKSQPDSAGKWDVAQAPKAGNWGGTFLGVPKSGKHVKEAQKLVT
                     WLTAPEQQAKLFSKMGSFPSAPAAYKLPQVTGGKNDMTGDAPIGELFAKAAEQIPTQVI
                     GPKDQIVQQGLTDNGVILVTQGKSAEDAWDNAVKTIDNNLEK"
     misc_feature    26418..26450
                     /gene_synonym="2SCC13.03"
                     /locus_tag="SCO2795"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site"
     PFAM_domain     26559..27476
                     /aSDomain="SBP_bac_8"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13416.9"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2795_0286"
                     /evalue="6.90E-24"
                     /label="SCO2795"
                     /locus_tag="SCO2795"
                     /protein_end="371"
                     /protein_start="65"
                     /score="85.3"
                     /tool="antismash"
                     /translation="YDEYEKLNPDINIEENVTERNENYYPALVNHLTTNSGLQDVQAIE
                     VGNIAEVVATQADKFEDMSKAAGVQKANWLDWKWQQATTKDGATIGLGTDIGPMAICYR
                     KDLFEKAGLPTDREEVSKLWAGDWNKFIEAGEKYKKGAGKDTYFMDSPGGLINAILSSE
                     DEKFYDASGKVIYKTNPAVKDAFDLTAEAAEKGLVQSQTQFQPAWDQTISNSLFATVAC
                     PPWMLGTIKAKSQPDSAGKWDVAQAPKAGNWGGTFLGVPKSGKHVKEAQKLVTWLTAPE
                     QQAKLFSKMGSFPSAPAAYKLPQVT"
     misc_feature    26814..27674
                     /gene_synonym="2SCC13.03"
                     /locus_tag="SCO2795"
                     /note="Pfam match to entry PF01547 SBP_bacterial_1,
                     Bacterial extracellular solute-binding protein, score
                     35.20, E-value 7.1e-09"
     regulatory      27680..27683
                     /gene_synonym="2SCC13.03"
                     /locus_tag="SCO2795"
                     /regulatory_class="ribosome_binding_site"
     gene            27695..28708
                     /db_xref="GeneID:1098230"
                     /gene_synonym="2SCC13.04"
                     /locus_tag="SCO2796"
     CDS             27695..28708
                     /codon_start=1
                     /db_xref="GeneID:1098230"
                     /gene_functions="transport (smcogs) SMCOG1067:putative ABC
                     transporter permease protein (Score: 273; E-value:
                     4.6e-83)"
                     /gene_kind="transport"
                     /gene_synonym="2SCC13.04"
                     /locus_tag="SCO2796"
                     /note="2SCC13.04, probable cellobiose transport permease,
                     len: 337 aa; highly similar to TR:Q9X9R6 (EMBL:AJ009797)
                     Streptomyces reticuli permease CebF protein, 305 aa; fasta
                     scores: opt: 1416 z-score: 1722.4 E(): 0; 67.9% identity in
                     296 aa overlap. Contains Pfam match to entry PF00528
                     BPD_transp, Binding-protein-dependent transport systems
                     inner membrane component and match to Prosite entry PS00402
                     Binding-protein-dependent transport systems inner membrane
                     comp sign. Also contains possible hydrophobic membrane
                     spanning regions"
                     /product="cellobiose transport permease"
                     /protein_id="NP_627026.1"
                     /transl_table=11
                     /translation="MTTRHDTAASPVKGGAAPGRPPGGRASAEADRRKRAKLSRRWQRD
                     MRWSPYAFVSPFFLLFLAFGLFPLIYTGWASLHTVELTAPTDMQWTGLDNYTRIFDDEF
                     FWNAAKNTLWIGVISTVPQLLMAMGLAHILNYKLRASTFYRVVMLAPYATSIAAASLVF
                     VLLFGRDYGMINWVLDLVGLDKIDWQNGSWSSKFAVSTIVIWRWTGYNALIYLAAMQAI
                     PQDLYESAALDGASRWRQFIHVTLPSLRPTILFTVVVSTIGASQVFGEPLLFDANKGAS
                     GGSQHQFQTLGLYLYEQGWVNQHLGRASAIAWAMFLILIVIGVLNAVISRRLRASS"
     PFAM_domain     28067..28696
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00528.25"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2796_0287"
                     /evalue="2.30E-19"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO2796"
                     /locus_tag="SCO2796"
                     /protein_end="334"
                     /protein_start="124"
                     /score="70.0"
                     /tool="antismash"
                     /translation="LMAMGLAHILNYKLRASTFYRVVMLAPYATSIAAASLVFVLLFGR
                     DYGMINWVLDLVGLDKIDWQNGSWSSKFAVSTIVIWRWTGYNALIYLAAMQAIPQDLYE
                     SAALDGASRWRQFIHVTLPSLRPTILFTVVVSTIGASQVFGEPLLFDANKGASGGSQHQ
                     FQTLGLYLYEQGWVNQHLGRASAIAWAMFLILIVIGVLNAVISRRLR"
     misc_feature    28346..28588
                     /gene_synonym="2SCC13.04"
                     /locus_tag="SCO2796"
                     /note="Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 54.20, E-value 2.8e-12"
     misc_feature    28349..28435
                     /gene_synonym="2SCC13.04"
                     /locus_tag="SCO2796"
                     /note="PS00402 Binding-protein-dependent transport systems
                     inner membrane comp sign."
     regulatory      28707..28712
                     /regulatory_class="ribosome_binding_site"
     gene            28721..29632
                     /db_xref="GeneID:1098231"
                     /gene_synonym="2SCC13.05"
                     /locus_tag="SCO2797"
     CDS             28721..29632
                     /codon_start=1
                     /db_xref="GeneID:1098231"
                     /gene_functions="transport (smcogs) SMCOG1069:putative ABC
                     transporter permease protein (Score: 261; E-value:
                     1.9e-79)"
                     /gene_kind="transport"
                     /gene_synonym="2SCC13.05"
                     /locus_tag="SCO2797"
                     /note="2SCC13.05, probable cellobiose transport permease,
                     len: 303 aa; highly similar to TR:Q9X9R5 (EMBL:AJ009797)
                     Streptomyces reticuli permease CebG protein, 275 aa; fasta
                     scores: opt: 1262 z-score: 1477.0 E(): 0; 67.8% identity in
                     276 aa overlap. Contains Pfam match to entry PF00528
                     BPD_transp, Binding-protein-dependent transport systems
                     inner membrane component and match to Prosite entry PS00402
                     Binding-protein-dependent transport systems inner membrane
                     comp sign. Also contains possible hydrophobic membrane
                     spanning regions"
                     /product="cellobiose transport permease"
                     /protein_id="NP_627027.1"
                     /transl_table=11
                     /translation="MTTTMTKPPADAAPEPPRRGRRRSKASRAGGTLHAGPVAYIILAL
                     FTIGSLFPLVWTAIAASRDNQRLAQTPPPLWFGGNLFDKLEIAWNDANLGEAFLNTTIV
                     AGISACTIVFLSTVAGFAFAKLRFRGRNALMLIVVGTMMVPPQLSIIPLYMMVAKLDWS
                     DQLQAVILPSLVNAFGVFFMRQYLLQALPDEIIEAARVDGASSWRVMWHVVFPAARPAM
                     AVLGMLMFVQSWNDFLWPFLVLTQNGSPTVQVALAGLGRGYTPDQSLIMAGALLGTLPL
                     LLVFAIFGKQIVGGIMQGAVKG"
     PFAM_domain     29069..29593
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00528.25"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO2797_0288"
                     /evalue="1.60E-20"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO2797"
                     /locus_tag="SCO2797"
                     /protein_end="291"
                     /protein_start="116"
                     /score="73.8"
                     /tool="antismash"
                     /translation="TVAGFAFAKLRFRGRNALMLIVVGTMMVPPQLSIIPLYMMVAKLD
                     WSDQLQAVILPSLVNAFGVFFMRQYLLQALPDEIIEAARVDGASSWRVMWHVVFPAARP
                     AMAVLGMLMFVQSWNDFLWPFLVLTQNGSPTVQVALAGLGRGYTPDQSLIMAGALLGTL
                     PLLLVFAIFGKQ"
     misc_feature    29279..29503
                     /gene_synonym="2SCC13.05"
                     /locus_tag="SCO2797"
                     /note="Pfam match to entry PF00528 BPD_transp,
                     Binding-protein-dependent transport systems inner membrane
                     component, score 65.80, E-value 8.9e-16"
     misc_feature    29282..29368
                     /gene_synonym="2SCC13.05"
                     /locus_tag="SCO2797"
                     /note="PS00402 Binding-protein-dependent transport systems
                     inner membrane comp sign."
     misc_feature    complement(29762..29776)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.66"
                     /tool="antismash"
     misc_feature    29763..29777
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.62"
                     /tool="antismash"
     regulatory      29765..29768
                     /regulatory_class="ribosome_binding_site"
ORIGIN
        1 cgaggacgac gtgcagcagg gggtcgtccg cgagcttgcc gttggtgcgg aaccacacct
       61 gggagtgcgg ttcgcgcggg gtgccgaagt cgccgaaggg cgggtcgtcg acgtagcgca
      121 ggtcgacggc ggcgcgggcc tccaggaagc gctccaccgt ctcggcgggc aggtgcgggt
      181 agccgcgcag ccgctcctcg ccggtgggga gggtcgccgg gtccggtgcg gacggcatcg
      241 gggcctggtg gtccaggccc tcctcgtacg tctggaagga cgccgacagg gtgaagatcg
      301 gcttgccgtg ctggacggcg acgacgcggc gggtggtgaa ggagcggccg tcgcgcagcc
      361 ggtcgacgtt gtagacgatg ggggcgccgg ggtcgccggg gcgcaggaag tacgcgtgca
      421 gggagtgcgc gtgccggtct ccggggacgg tgcggccggc ggcgaccatg gcctgggccg
      481 ccacctgtcc gccgaagacc cgggggacga cggcggaccg ggagcggccg cggtagatgt
      541 cctcctcgat ccgctcgagg tcgagcaggt cgaggaggga ctggagtgct tcgctcatga
      601 cctgtggtct acaggcccat gttcttcgcg atgatcgact tcatgatctc gctggtgccg
      661 ccgtagatgc ggttgacgcg gttgtccgcg tacaggcggg cgatcgggta ctcgttcatg
      721 tagccgtagc cgccgtgcag ctggaggcag cggtcgatga cgcggtgggc gacctcggtg
      781 cagaacagct tggcgctggc ggcctcggcg ggggtcagct cgccggcgtc cagggcctcg
      841 gtcgcgcggt cgacgacggc ctcggcggcg tccacctcgg cctggcaggc ggccagctcg
      901 aacttggtgt tctggaagtg ggcgaccggc ttgccgaaga cggtgcggtc ctgcacgtac
      961 tgcttggcga accggacggc ggccttggcc tgcgcgtagg cgccgaaggc gatgccccag
     1021 cgctcggagg ccaggttgtg gccgaggtag gagaagccct tgttctcctc gccgagcagg
     1081 tcctcgacgg ggaccttgac gtcgacgaag gccagctcgg cggtgtcgga ggtgcgcagg
     1141 cccagcttgt cgagcttgcg gccgaccgag tagccctcgg acttggtgtc cacggcgaac
     1201 agggagatgc cgtggcggcg gtcctcggcc gtgggcgcgt cggtgcgggc gcagacgatg
     1261 acgcggtcgg cgtgcacgcc gccggtgatg aaggtcttgg cgccgttgag gacgtagtgg
     1321 gtgccgtcct cggagagctt ggcggtggac ttcatgcccg cgaggtcgga gccggtgccc
     1381 ggctcggtca tcgcgatggc ccacatctcc tcgccggtga cgaacttcgg caggtagcgc
     1441 ttcttctgct cgtcggtggc cagcatgttg atgtagggca gggcgagcag cacgtggacg
     1501 ccggagccgc cgaactggac gcccgcgcgg gcggtctcct cgtagaggac ggcctcgaac
     1561 ttgtggctgt ccatgccggc gccgccgaac tcctcgggca cgttgatgcc gaagatgccc
     1621 agctcgccga gcttgtagta gaactcgcgc ggcgcctggc ccgcggcgaa ccagtcgtcg
     1681 tagacgggga cgacctcggc ctcgatgaag gcgcggaggg tctcccggaa cgcctcgtgg
     1741 tcctcgttga acaccgtacg gcgcaccgcg ccacctccag ggtacgaata tctaagcgct
     1801 tgctcagata tcaccgtacc ggcgggtagc cgaaggcgtc cagaccggga cgcgggtaac
     1861 cctcgtcact ccccgcctca ggggaggggc gcccgctacg cctcccccac cgccgcgaac
     1921 gccccccggg ccatccggtg cagcagggac gccgtcaccg cgcggccggg cagggagccg
     1981 gggcggccca ggtggggggt ggagttcagg aggccgaaga ccgagtggac cgcggagcgg
     2041 gcggcgggct cggcgaccgc cgggtagacc tcccggagca ccccgaccca cagctccacg
     2101 tactgccgct gcaactgccg caccatcttg cggtcggcgt cccggaggcg gtccagctcg
     2161 cggtcgtgca gggtgatgag cgggcggtcg tcgagcgcga agtcgatgtg ccccgcgatg
     2221 agcgagtcga ggaccgcccc cggccccgtc gggccggtgc ccgcccggga gccggccgcc
     2281 ccgtccgcct ccgccagccg ccgcttcgcc ccggtcagca gcgagtcgct gatcccgacc
     2341 agcagctcgg cgagcatcgc gtccttgccg gggaagtgcc ggtagaggcc ggggccgctg
     2401 atgccgaccg cggcgcctat ctcgtcgacg cccaccccgt ggaagccgcg ctcggcgaag
     2461 agccgggcgg cctccttgag gatctgctcg cggcgggtgg gggcgtcggt tctggtggcc
     2521 atgaagtcga ttctagacag gcgggttagc ggtcgttaac ctgaaggaaa tgcgttaacg
     2581 ctcattaact ggtcgaccac tgggtgaggg gaccgcagga tgcacgaggc accggagctg
     2641 acgacggcgg cagatcccgc gtcggaggcc tttcgggcca acgaggaggc gcacgccgcc
     2701 ctcgttcagg aactgcgcgc caagctcgcg gcggcccggc tgggcggcgg cgagcgggcg
     2761 cgggcccggc acaccgcgcg gggcaagctg ctgccgcgcg accgcgtgga cacgctgctc
     2821 gacccgggct cgccgttcct ggagctggcg ccgctcgccg ccgacgggct ctacgacggg
     2881 gcggccccgg ccgccggcgt gatcgccggg atcggccggg tcagcggccg ggagtgcgtg
     2941 atcgtggcga acgacgccac cgtcaagggc ggcacgtact acccgatgac cgtgaagaag
     3001 cacctcaggg cgcaggaggt ggcgctggag aaccggctgc cgtgcctgta cctggtggac
     3061 tcggggggtg ccttcctgcc gatgcaggac gaggtcttcc ccgaccgcga gcacttcgga
     3121 cggatcttct acaaccaggc ccggatgtcc ggcgcgggca tcccgcagat cgcggccgtc
     3181 ctcggctcct gcacggcggg cggcgcgtac gtcccggcga tgagcgacga ggcggtgatc
     3241 gtccgcaacc agggcacgat cttcctgggc ggcccgccgc tggtgaaggc ggccaccggc
     3301 gaggtggtca cggcggagga gctgggcggc ggcgaggtcc actcgcgcgt gtccggtgtg
     3361 accgaccacc tcgcggagga cgacccgcac gccctgcgca tcgtgcggca gatcgtctcc
     3421 accctgccgg agcgcggcgc cctcccctgg ggcgtggagg cggccgccga gccgaaggcg
     3481 gacccgcagg acctgtacgg cgtggtgccg gtcgactccc gcacccccta cgacgtccgc
     3541 gaggtcatcg cgcgcgtggt ggacggctcc cgcttcgccg agttcaagtc cgagtacggg
     3601 cagaccctgg tcaccggctt cgcccgcatc cacggccacc cggtcggcat cgtcgccaac
     3661 aacggcatcc tgttctccga gtcggcccag aagggcgccc acttcatcga gctgtgcgac
     3721 cagcgcggca tcccactggt gttcctgcag aacatctccg ggttcatggt gggccgggac
     3781 tacgaggccg gtggcatcgc caagcacggc gccaagatgg tgacggcggt ggcgtgcacg
     3841 cgcgtgccga agctgacggt ggtcgtcggc ggctcgtacg gcgcgggcaa ctactcgatg
     3901 tgcggtcggg cgtattcgcc gcgcttcctg tggatgtggc ccaacgccaa gatctccgtg
     3961 atgggcggcg agcaggccgc gtccgtgctg gccacggtca agcgggacca gctggagggg
     4021 cgcggcgagg agtggccggc cgaggaggag gagtccttca aggcaccggt gcgcgcccag
     4081 tacgagcgcc agggcaacgc ctactacgcg accgcccgcc tgtgggacga cggcgtgatc
     4141 gagcccgccg acacccggca ggtgctgggc ctggccctga ccgcgtgtgc caacgcgccg
     4201 ctgggcgagc cccggttcgg cgtcttccgg atgtgaggag gggacccatg gacaacacga
     4261 aggacacgcc gcgcatgttc gacaccgtgc tcgtcgccaa ccgcggcgag atcgccgtcc
     4321 gcgtcatccg gacgctgcgc tcgatgggcg tgcgctcggt ggcggtcttc tccgacgccg
     4381 acgcggacgc acggcacgtg cgggaggcgg acgacgcggt acggatcggc ccggcgcccg
     4441 cgacggagag ctatctgtcc gtcgagcggc tgctggcggc ggcggcccgg acgggggcgc
     4501 aggccgtcca cccgggatac ggcttcctcg ccgagaacgc gggtttcgcg cgggcctgcg
     4561 aggaggcggg gctggtcttc atcgggccgt ccgccgacgc gatcgccctg atgggcgaca
     4621 agatccgcgc caaggagacg gtgcgggcgg ccggggtgcc ggtcgtcccc ggctccagcg
     4681 gcagcgggct caccgacgag cagctcgccg acgccgcccg cgagatcggc accccggtgc
     4741 tgctcaagcc gtcggcgggc ggtggcggca agggcatgcg gctggtgcgg gacacggcgg
     4801 tgctggccga cgagatcgcc gccgcgcgcc gcgaggcccg cgcctccttc ggcgacgaca
     4861 cgctgctggt ggagcggtgg atcgaccgtc cccggcacat cgagatccag gtgctggccg
     4921 acggccacgg gggcgtggtg cacctgggcg agcgcgagtg ctcgctccag cgccgccacc
     4981 agaaggtgat cgaggaggcg cccagcgtcc tgctggacga ggcgacccgg gcggcgatgg
     5041 gcgaggcggc cgtgcaggcg gcccggtcct gcggctaccg gggcgcgggc acggtggagt
     5101 tcatcgtgcc cgggagcgac ccctcccagt actacttcat ggagatgaac acccgtctcc
     5161 aggtcgagca cccggtgacg gagctggtga ccggcctgga cctggtggag tggcagctgc
     5221 gggtggcggc gggcgagccg ctcgggttcg ggcaggagga cgtacggctg accgggcacg
     5281 cgatcgaggc ccggctgtgc gcggaggacc cggcgcgcgg cttcctgccc tccggcggca
     5341 cggtgctgcg gctgcgcgag cccgagggcg acggcgtgcg caccgactcg gggctcagtg
     5401 agggcaccga ggtcggcagc ctctacgacc cgatgctgtc caaggtgatc gcgtacggcc
     5461 ccgaccggga gaccgcgctg cgcaggctcc gggcggcgct ggccgggacg gtcaccctgg
     5521 gcgtgcagac caacgccggg ttcctgcggc ggctgctcgc gcacccggcg gtggtggcgg
     5581 gcgagctgga cacggggctg gtggagcgcg aggtcgacgg cctggtcgcc accgacgtac
     5641 cggaggaggt gtacgaggcg gcggcggccg tacggctgga ggcgctgcgc ccgcgcgggg
     5701 acggctggac ggacccgttc tcggtgccga gcggctggcg gatgggcggc gagccgaagg
     5761 cggccgcctt ccacctccgg gtcaccgacc cggtggaaca caccccgcgc ggaacccaca
     5821 ccgtcaccgg ggaccgggtc acggtcaccc tggacggcgt ccggcacacc ttccaccgcg
     5881 ccgccgactg gctgggccgc gacggcgacg cctggcaggt gcgcgaccac gacccggtgg
     5941 ccgcctccct caaccggtcc gcccacgcgg gcgccgactc gctgaccgcg ccgatgccgg
     6001 gcacggtgac ggtggtgaag gtcgccgtcg gcgacgaggt gagcgccggg cagagcctgc
     6061 tggtggtgga ggcgatgaag atggagcacg tcatctccgc cccgcacgcg ggcaccgtcg
     6121 ccgagctgga cgtggcgccg ggcacgacgg tcgccatgga ccaggtgctc gcggtcatcg
     6181 cacccaccga cgacgcgacg gaggagacgg catgaacgcc ccggaaccgg gcctcccgat
     6241 ggccgtaccg gccgagggac tgcccgcccg cgtccgcatc cacgaggtcg gcgcgcgcga
     6301 cggactgcag aacgagaagg cgaccgtgcc gacggccgtc aaggcggagt tcatccgccg
     6361 gctggccggc acgggcctga ccacgatcga ggcgacgagc ttcgtccacc ccaagtgggt
     6421 cccccagctg gccgacgccg aggacctgta cccgcggatc tccggcctgc cggtggagct
     6481 gccggtgctg gtgccgaacg aacgcggcct ggaccgggcc ctcgcgctcg gcgcgcgccg
     6541 ggtcgcggtg ttcgccagcg cgaccgagtc cttcgccaag gccaacctca accgcaccgt
     6601 ggacgaggcg ctggccatgt tcgagcccgt ggtgacccgg gcgaaggcgc agggcgacga
     6661 cgtccgtgta cggggctacc tctcgatgtg cttcggcgat ccgtgggagg gcccggtcgc
     6721 cgtcccccag gtggtgcggg tctgccgggc cctgctggac atgggctgcg acgagctgag
     6781 cctcggcgac accatcgggg tggcgacccc gggccatgtg acggcgctgc tcaccgcgct
     6841 gaccggggcg ggcgtgccgg tctccgcgct gggcgtgcac ttccacgaca cctacggcca
     6901 ggccctggcc aacacgctgg ccgcgctcca gcggggcgtc accaccgtcg acgcctccgc
     6961 cggcgggctc ggcggctgcc ccttcgcgaa gtccgccacc ggcaacctcg ccaccgaaga
     7021 cctcgtgtgg atgctgcggg gcctcggcat cgacaccggg gtcgacctcg gccgtctcgt
     7081 cgccacaagc gtctggatgg ccgcgcacct gggccggccg agcccgtccc gcaccgtacg
     7141 agccctctcc caccaggagt cgtgaacacc atggaccaca agctctcccc cgaactggaa
     7201 gaactgcgcc gtacggtcga acagttcgcg cacgacgtgg tggcgcccaa gatcggcgac
     7261 ttctacgagc ggcacgagtt cccgtacgag atcgtccgcg agatgggccg catgggcctg
     7321 ttcgggctgc cgttcccgga ggagtacggc ggcatgggcg gcgactactt cgccctcggc
     7381 gtggccctgg aggagctggc ccgggtcgac tcgtcggtgg cgatcacgct ggaggcgggt
     7441 gtctcgctgg gcgcgatgcc gctgcacctg ttcggcaccg aggagcagaa gcgcgagtgg
     7501 ctgccccggc tctgctcggg cgagatcctg ggcgcgttcg gtctcaccga gccggacggc
     7561 ggcagcgacg cgggcgcgac ccgtaccacg gcccgcctgg acgaggctac gaacgaatgg
     7621 gtcatcaacg gcaccaagtg cttcatcacc aactccggca cggacatcac gggcctggtc
     7681 acggtcacgg cggtgaccgg ccgcaagccc gacggcaggc ccctgatctc gtcgatcatc
     7741 gtcccgtcgg gcaccccggg cttcacggtg gccgccccgt actcgaaggt cggctggaac
     7801 gcctcggaca cccgtgagct gtccttcgcc gacgtccggg tcccggcggc gaacctgctg
     7861 ggcgagctgg ggcgcggcta cgcgcagttc ctgcgcatcc tggacgaggg ccgggtggcg
     7921 atcgccgcgc tgggcacggg gctcgcgcag ggctgtgtgg acgagtcggt cgcctacgcg
     7981 aaggaacgtc acgccttcgg caggcccatc ggcgccaacc aggccatcca gttcaagatc
     8041 gccgacatgg agatgaaggc ccacacggcc cgtctcgcct ggcgggacgc ggcctcgcgg
     8101 ctggtggcgg gcgagccgtt caagaaggag gcggcgctgg cgaagctgta ctcgtcgacg
     8161 gtcgcggtgg acaacgcccg ggacgccacc caggtccacg gcggctacgg tttcatgaac
     8221 gagtacccgg tggcccgcat gtggcgggac gcgaagatcc tggagatcgg cgagggcacc
     8281 agcgaggtcc agcggatgct gatcgcacgg gagttggggc tggtgggctg aggctccgag
     8341 gcggcggggg cgggcgccgc accggccccg cccctggaca agatctgagg ttaggctaac
     8401 ctaccttcga attgtcccgc agggcgcgac gctccgcacc gttcgaaggc agccaccacc
     8461 atgtcccacg ccagcgctac ccacccgacc cgccgtggaa tcctcgccgc cggcggcgcc
     8521 ctcggcctcg gcgccgtgct cgcggcctgc ggcgacggcg acggcaagag cgatggggcg
     8581 ggcgacgggt cgggcggcgc cgccaagtcc ggcccctggt ccttcaagga cgaccgcggc
     8641 acgaccgtga agctggacaa ggtgccggcg aacatcgtcg ccttcacggg tgtcgccgcc
     8701 gccctcttcg actacggcgt cgaggtcaag ggcgtcttcg gcccgaccac caccaaggac
     8761 ggcaagcccg acgtgcaggc cggcgacctc gacgtcgaca aggtcaccgt gctcggcaac
     8821 gagtggggca agctcaacgt cgagaagtac gcctccctcg ccccggaggt gctcatcacc
     8881 acgacgttcg acaccgcggg caccctgtgg tccgtcccgg aggagtcgaa ggacaaggtc
     8941 gccaagctcg ccccgagcgt cgcgatctcg gtcttcgacc gccagctcac ccagccgctc
     9001 cagcgcatgt gggagctggc ggagtcgctc ggcgcggaca tgaaggccaa gaaggtcacc
     9061 gacgccaagg ccgccttcga caaggccgcc gcccggctgc gcgccgccgc caaggccaag
     9121 ccggagatcc gggtgctggc cggttccgcg agccccgacc tgttctacgt ctccggcacc
     9181 aacctctcgg tggacctgga gtacttcaag gccctcggcg tgaacttcgt cgagccctcc
     9241 gaggacgcca agaaggcgac cggcggctgg ttcgagtccc tgagctggga gaacgtcgac
     9301 aagtacccgg ccgacgtcat catcatggac gaccgcgcct cgaccatcca gcccgccgac
     9361 atcaccgagg gcacctggaa gcagctcccc gcggtcaagg ccggacaggt catcgcccgc
     9421 tcccccgagc cgatcctgtc ctacgacaag tgcacgccgc tcctcgacaa cctggccgag
     9481 gcgatcgaga acgccaagaa ggtcggctga cccgcccccc tcccccggag cccctcatga
     9541 ggacggccgt cgccgccccg ttccgtttct tcgccctcca ggtcgtacgg acgaggcggt
     9601 tggggggtgt cgattggatc aggccggctc cggccaacgg tgcttcgctg ccgacccgag
     9661 cggggtccgg tgcgtgcagc tgcacggcgg aggagggcga cagggcggag ccccggcaac
     9721 cgacgacaac gccgcagatg cgcgtgccag accccgcgcc cccggcagga tccaaacgac
     9781 accccccaag cccggccctg gcccgggtca ccttcgcggg gcccgacctg cgcgccttcc
     9841 gctccgacgg cctcgaccag tcgctgtcgc tgttcctgcc gcacccgggg caggcggagc
     9901 ccgcggtccc ggtggagctg ggcgagggct ggtggcaggg ctggcgggaa ctgccggagg
     9961 acgtacgggc ggtgatgcgc tcgtacacgc tgcggtcact gcgccgcgac accgacgggc
    10021 acaccgccga gatcgacgtc gacttcgtcc tgcacggcct cgaaccggac tcggggatcc
    10081 aggccggtcc cgccgcccgc tgggccgccg acgccgcccc cggcgaccgc gtgctgctgc
    10141 tcggcccggc ggtcgccgac aaccgggcga tccgcttccg gccgcccgag gacaccgacc
    10201 tggtggtgat ctggggtgac gagacagccg tacccgccgc ctgcgccatc gtggaggcac
    10261 tgccggccgg cacccgcgcg cgggtctggc ttcaggtgcc gcacgccgag gacgtgcagg
    10321 acctccggac ggccgcggac gccgagatca cctggctggt cggggacgcc gccgacgggc
    10381 ccgaggcgac cctcgccacc ctccgcgccg cccaactgcc gcccgccgaa cacccctacg
    10441 tctggatcgc gggcgagtcc ggctgcgtga agcggctgcg gcggcacttc gtgggcgagc
    10501 gcggcgtcga ccgacggcgc gtcaccttcg tcggctactg gcgccggggc ctgacggagg
    10561 aacaactccg cgagcagggc tgaggaccgc acccgcccca cccggccgca cggagggcgt
    10621 gagtgacagc ggtcacccac aggcacgcgt ttgatcgact taacttaggt taggctcacc
    10681 taagtcgtag cgagggctcc ggccctcccc acccctctcg gaccgtcccc accggaggac
    10741 ccccccatgc gctcgcacct gctcaacgac accaccgcgg agcagtaccg ccgttccgtg
    10801 accgaaggag tcgagcgggt ggccgccaaa ctcgccacca ccgaccgccc gttcaccggc
    10861 gtcacggtcg acgccctctc cccccgcatc gacgcgatcg acctcgacga gccgctgcac
    10921 gacaccgccg cggtcctcga cgagctggag gacgtctacc tccgcgacgc cgtctacttc
    10981 caccaccccc gctacctcgc ccacctcaac tgcccggtcg tcataccggc gctgctcggt
    11041 gaagcggtcc tgtccgccgt caactcctcc ctggacacct gggaccagtc ggccggcggc
    11101 acgctcatcg agcggaagct gatcgactgg acctgcgccc gcatcggcct cggcccggcg
    11161 gccgacggcg tgttcacctc cggcggcacc cagtccaacc tccaggcgct gctcctcgcc
    11221 cgcgaggagg cgaaggccga ggacttcgcc gacctgcgga tcttcgcctc cgaggccagc
    11281 cacttcagcg tcaggaagtc cgcgaaactg ctcggcctcg gccccgacgc cgtcgtgtcg
    11341 atcccggtcg accgcgacaa gcggatgcag accgtcgccc tcgcccgcga gctggagcgc
    11401 tgcgcgcggg acggcctggt ccccatggcc gtcgtcgcca ccggcggcac caccgacttc
    11461 ggctcgatcg acccgctgcc ggagatcgcc gggctgtgcg agcagtacgg cgtgtggatg
    11521 cacgtcgacg cggcctacgg ctgcgggctg ctcgcctccc tgaagtaccg ggaccgcatc
    11581 accggcatcg agcgggccga ctcggtcacc gtggactacc acaagtcctt cttccagccg
    11641 gtgagttcgt cggccgtgct ggtccgggac gcggccaccc tgcgccacgc cacctaccac
    11701 gcggagtacc tcaacccgcg ccgcatggtg caggaacgta tccccaacca ggtggacaag
    11761 tccctccaga ccacccgccg cttcgacgcg ctcaagctgt ggatgacgct gcgcgtgatg
    11821 ggcgccgacg gcatcggcgt cctcttcgac gaggtgtgcg acctggccgc cgagggctgg
    11881 aaactgctcg ccgccgaccc gcgcttcgac gtcgtggtcc agccgtcgct gtccacgctg
    11941 gtcttccgcc acatcccggc ggacgtcacc gatcccgccg agatcgaccg cgccaacctg
    12001 tacgcccgca aggccctgtt cgcgtccggc gacgccgtgg tcgcgggcac caaggtcgcc
    12061 ggtcgccact acctgaagtt caccctgctc aaccccgaga cgaccccggc cgacatcgcc
    12121 gccgtcctcg acctgatcgc cggccacgcc gagcagtacc tgggagactc ccttgaccgc
    12181 gcttcctgaa gccagcgccc cgtacgactt cgtgggcatc ggcctcggcc ccttcaacct
    12241 cggcctcgcc tgcctcaccg agcccgtcgc cgagctgaac ggcgtcttcc tggagtccaa
    12301 gccggacttc gagtggcacg ccgggatgtt cctggacggc gcccacctcc agaccccgtt
    12361 catgtcggac ctggtgacgc tcgccgaccc gacctcgccg tactccttcc tcaactacct
    12421 gaaggagcag ggccggctgt actccttcta catccgggag aacttctacc cgctgcgggt
    12481 cgagtacgac gactactgcc gctgggccgc gcgcaagctg agcagcgtcc gcttctccac
    12541 cacggtcacc gaggtcacgt acgacgagcg cgaggagctg tacgccgtcg ccaccacgtc
    12601 cggcgacacc taccgcgccc gccgcctcgt cctcggcacc ggcaccccgc cgcacatccc
    12661 ggacgcctgc cggggcctgg ccggcgactt cctccacaac tcccggtacg tgcggcaccg
    12721 ggcggagctg gtgaagaaga agtcgatcac gctggtcggc agcggccagt ccgccgccga
    12781 gatctaccag gacctgctga gcgagatcga cgtccacggc tacgggctga actgggtgac
    12841 ccgctccccg cggttcttcc cgctcgaata caccaagctc accctggaga tgacgtcccc
    12901 ggagtacgtg gactactacc acgcgctgcc cgaggacacc cgctaccgcc tcacggccga
    12961 gcagaagggc ctgttcaagg gcatcgacgg cgacctgatc aacgagatct tcgacctgct
    13021 ctaccagaaa cggctcggcg gccccgtccc cacccgcctg ctcaccaact cggcgctgac
    13081 cagcgcccgg tatgcggacg gcacctacac gctcgggttc cgccaggagg agcagggcac
    13141 ggacttcgag atcgagaccg agggcctggt cctcgccacc ggctaccggt acaccgagcc
    13201 ggagttcctc aagcccgtcc gggaccggct gcgctacgac tcccgcggca acttcgacat
    13261 cggccgcaac tacgccgtcg acgtcacggg aggcggcgtg ttcctccaga acgcgggggt
    13321 ccacgcgcac agcgtcacca gccccgacct gggcatgggc gcctaccgca acagctgcat
    13381 cgtccgggag ctgctcggac gcgagtacta cccggtcgag cagtcgatcg cgttccagga
    13441 gttcgccgta tgagccgctt gagcaccacc acccccgtcg gggcactgac cctgcgcccc
    13501 gtcgacccgc tgacggacgc cgtactgctg cacggctggc tcacccaccc caagtccgcg
    13561 ttctggatga tgcaggacgc ccggctggtg gacgtcgagc gggcctacat ggagctggcc
    13621 gccgacgagc accagcaggc ccacctcggc ctgcacgacg gggtcccggc cttcctgacg
    13681 gagcgctacg accccgccca ccgcgaactg gtcgggctgt acgagcccga gccgggcgac
    13741 gtcggcatgc acttcctggt cgcgcccacc gaccggcccg tgcacggctt cacccgcgcc
    13801 gtgatcacca ccgtgatgac ggagctgttc gccgacccgg cgacccggcg ggtcgtcgtc
    13861 gaaccggacg tcaccaacac cgccgtgcac gccctgaacg cagccgtcgg attcgtgccc
    13921 gagcgcgaga tccagaagcc ggagaagaag gccttgctga gcttctgcac ccgcgagcag
    13981 ttcgcgaagg cggtgtccgc atgagcctcg ccgacgccgt cgcccacctg acccccgaac
    14041 gctgggagga ggccaaccgc ctcctggtcc gcaaggcgct ggccgagttc acccacgagc
    14101 ggctgctgac ccccgagcgg gagccggacg acgggggcgg gcagacgtac gtcgtccgca
    14161 gcgacgacgg ccagaccgcg taccgcttca ccgccaccgt ccgcgccctg gaccactggc
    14221 aggtggacgc cgcctccgtc acccgccacc gcgacggcgc ggaactcccg ctcgccgcgc
    14281 tggacttctt catcgagctg aagcagaccc tgggcctgag cgacgagatc ctcccggtct
    14341 acctggagga gatctcctcc accctctccg gcacctgcta caaactgacc aagccgcagc
    14401 tcagctccgc cgagctggcc cggagcggag acttccaggc cgtcgagacg ggcatgaccg
    14461 agggccaccc gtgcttcgtc gccaacaacg ggcgcctcgg cttcggcatc cacgagtacc
    14521 tgtcgtacgc ccccgagacc gcgagcccgg tccggctggt gtggctggcc gcgcaccgct
    14581 cgcgggcggc gttcacggcg ggcgtgggca tcgagtacga gtccttcgtc cgggacgagc
    14641 tgggcgcggc caccgtcgac cgcttccacg gcgtgctgcg cgggcgcggc ctggacccgg
    14701 ccgactacct gctcatcccg gtccacccct ggcagtggtg gaacaagctc accgtcacct
    14761 tcgccgccga ggtcgcccgc gggcacctgg tgtgcctggg cgagggcgac gacgagtacc
    14821 tggcccagca gtccatccgc accttcttca acgcctcgca ccccgggaag cactacgtga
    14881 agactgccct gtccgtcctc aacatgggct tcatgcgcgg tctgtcggcg gcgtacatgg
    14941 aggccactcc ggccatcaac gactggctcg cccggctgat cgagggcgac ccggtgctga
    15001 aggagacggg gctgagcatc atccgggagc gggcggccgt cggctaccgg cacctggagt
    15061 acgagcaggc caccgaccgc tactcgccct accgcaagat gctggcggcg ctgtggcggg
    15121 agagcccggt gccgtccatc cgggagggcg agacgctcgc caccatggcc tccctggtcc
    15181 accaggacca cgagggcgcc tccttcgcgg gcgcgctgat cgagcggtcc ggactcacgc
    15241 ccaccgagtg gctgcggcac tacctgcggg cctactacgt cccgctgctg cacagcttct
    15301 acgcctacga cctggtgtac atgccgcacg gcgagaacgt gatcctggtg ctggcggacg
    15361 gggtggtgcg gcgggcggtc tacaaggaca tcgccgagga gatcgcggtg atggacccgg
    15421 acgcggtgct gccgccggag gtctcccgca tcgcggtgga cgtgccggac gacaagaagc
    15481 tcctgtcgat cttcacggac gtcttcgact gcttcttccg cttcctggcc gcgaacctgg
    15541 cggaggaggg gatcgtcacg gaggacgcct tctggcggac ggtcgcggag gtcacccggg
    15601 agtaccagga gtcggtgccg gagctggccg acaagttcga gcggtacgac atgttcgcgc
    15661 ccgagttcgc cctgtcctgc ctcaaccggc tccagctgcg cgacaaccgg cagatggtgg
    15721 acctggccga cccgtccggc gcgctccagc tcgtcggcac cctgaagaac cccctggcag
    15781 gccggtagcc aaccggcccc gcggacgggc gggcaccccg gagacggtcc tcgggggtgc
    15841 ccgtcgtgcc gtccgggtca ggtccagggc acctgcggcg agcggtagta gtcgatcccc
    15901 atcgcctccc agtgcggtgc ctgtccggcg agccgcacct tgtaggtgtc ccagtcgtgc
    15961 gtcgacgccg gggaccagcc cagctcggcg acgcccggca gcctcgggaa ggccatgaag
    16021 tccagctggt ccgggtcgga cagggtctcc gtccacagcg gggcctcgac gccgcggacc
    16081 gcctcggccg gggcgcccgg cagataggcg gccgggtccc agtcgtagga ccgccgcacc
    16141 tcgacgtagc ccgcccagga cagccccagc ggagtgtcct tggtgtactt catgtccagg
    16201 tacgtccggt cggccgggga gaggatcagc ccggtgccgt tcctggcggc cgcggcgacc
    16261 tgggccttct cggcgtcgct ggtgcggtcc aggccccagt actggacgag cgcaccctcg
    16321 accggttcgg cgccggccag ctggtgccag ccgacgaccg tcttgccgta cttggcgacg
    16381 atcggctgca cccgcttcat gaacgccacg aagtcggcct gcggcgtgga gtgcgcctcg
    16441 tcgccgccga tgtgcaggta gcggccgggg gtgagcgcgg cgagttcgcc gaggacgtcg
    16501 tccacgaagt cgtacgtgac gtccttgtcc acgcacagcg tgctgaagcc gaccttggtg
    16561 ccggtgtaga gcgggggcgc cacgccgtcg cagttcagct cggcgtagga ggcgagggcg
    16621 gcgttggtgt ggccgggcat gtcgatctcg ggcacgacct ccagatggcg ggatgccgcg
    16681 tagcggacga tctcctcgta gtccgccttg gtgtagtggc cgcctgggcc gccgccgacc
    16741 tcggtggagc cgccgtaggt cgccaggcgc ggccaggagt cgatggcgag gcgccagccc
    16801 tggtcgtcgc tgatgtgcag gtggagcttg ttgtacttgt agagggcgac gcggtcgatg
    16861 tagcgcttga cctcgtcgac gctgaagaag tgccgggaga cgtcgagcat ggcgctgcgc
    16921 caggcgtagc gcggggtgtc ctcgatggtg ccgcccgcga ccagccaggg tccgggctgc
    16981 gcggagtcct tctcgacggc ggcgggcagc agctgacgca gggtctggac gccgtggaag
    17041 agcccggcgg ccttgcgggc ggtgatggtg acgccctcgc gtccgctgtc gaggcggtag
    17101 ccctcgtcgc cgtacgggcc ctcggccagg cgcagtcgta tgccgccgtg gccgtgggag
    17161 gtgacgggga gccggtagcc ggtggcgggc cgcaggaggt ccgcgaggta gtcgccgacg
    17221 cggcgggcct cgcgggagtc gtccacgcgg atgtgggtgc ctcgggtgat gcggtacggg
    17281 gcgccgccgg gttcgaccga ggccggggcc gggatcaccc ggtccagggg ggtcggttcc
    17341 gcggccgcct tccggaccgg ggcggcgccg gtggtcatgg cgccgaccgc cgccaccagc
    17401 agcagcgatc ccaacagccg ggtgatgcgg ggagtcgttc tgtggtgccg tcgatgaggt
    17461 ctcacgtgcg ctcccttcgc gaggcgtgca atcagaggtc ctaggagggg ggttggggac
    17521 gggtgcggac cactctcccg caccatcacc gcccgcggcg gcgatgaaac aatccccgca
    17581 tggcggaaat catccagaag gacggaacgt gggtcttcga cggcgacgcc ctgcggctga
    17641 caccggggcg ggacaagaac gtcagtctgc tccgcaggga actgggtgaa ctgctcgtgc
    17701 cgctcgcggc gttggcgggc atatcgttcg agcaggggaa gaagtccggg cggctcaggc
    17761 tgcggctgcg ggacggcgcc gacccgttgc tgcacgcggc gggcggccgg ctgaccgagc
    17821 cgcacgaccc gtaccagctc ctcgtggagt ccgaccggta cggggtggcc gagtacttcg
    17881 tggacgaggt gcgcaacgcg ctgctcctcg accaggtccc gtccggcccg gtggacgcct
    17941 atctgctgcc ggggccctcg gtgccgctgt cggtgtcggc cggggacggg gtcgcgagct
    18001 tcgacgggga gcgggtgcgc ctggagtgga agtggcaggc ggaggacgcc aagtcggccg
    18061 cgggtccgcg cacgctgccc ctcgcggaca tcgtcgcggt ggaatggcag ccgacgatcg
    18121 gcctggagaa cggccacctc cggttcaccg tgcgggcggc gccgagcaag gtgccgccga
    18181 agtacgaccc caacgcggtg gagctgtggg gcttcaagaa ggacccgctg atggccctgg
    18241 tggccgcggc cgtccaggcc cgcctgccgc acccggccgc ccgcgcggcc ctggaggacg
    18301 cccgcgcggg cgaggacacc tccacgcccg ccaccgcacc accggcaccg gccgccgagg
    18361 acgatcacga cgcgctgctg cgccggctgc gggagctggg cgacctgcac cgctccgggg
    18421 tgctcacgga cgaggagttc gccctggcga agcaggcggt gctgaagcgc atgtagtcag
    18481 cacgacggac agcttccgcc aacacctgcc cgatatcggg caggattctt gcgcaagcac
    18541 ctctcttact ccaggatcta ccgggtgcac gacgaactcg ttgatcatct gacgcggtcc
    18601 accccgctga gccggggcga ggcgctgcgc gtggtccagg acgtgctcgc ctacttcgac
    18661 gagacgaccg aggagtacgt ccgtcgccgc caccgcgagc tgcaggccca gggcctggtg
    18721 aacgcgacga tcttcgagcg gatcgaggcg gaactgaaat accgggcggt cgcgccgccg
    18781 gagctgtcgc tccgtcagct gcgccgcatc gtctacggct gagcggccgc ctgcggctgg
    18841 aaggcccgcc cacggccgag aggccgaaga gagacagagg tttacgtata catgtgcgga
    18901 atcgtcggat acatcggcaa gcgtgacgtc gcccccctgc tcctggaggg tctccagcgc
    18961 ctggagtacc gcgggtacga ctcggcgggc atcgtggtga cctccccgaa ggcggccggc
    19021 ctgaggatgg tcaaggccaa gggccgggtg cgcgacctgg aggccaaggt cccggcgcgc
    19081 ttcaagggca ccaccggcat cgcccacacc cgctgggcca cccacggcgc cccctccgac
    19141 gtgaacgccc acccgcacat gtcggccgac aacaaggtcg ccgtcgtcca caacggcatc
    19201 atcgacaacg ccgccgacct gcgccgcaag ctggaggcgg acggcgtcga gttcctctcc
    19261 gagaccgaca ccgaggtcct cgtccacctc atcgcccgct ccgaggcgga gaagctggag
    19321 gacaaggtcc gcgagaccct gcgggtcatc gagggcacgt acggcatcgc cgtgatgcac
    19381 gccgacttcc ccgaacgcat cgtggtcgcc cgcaacggct cgccggtcgt cctcggcatc
    19441 ggcgagaagg agatgttcgt cgcctcggac atcgccgcgc tggtcgccca cacccggcag
    19501 atagtcacgc tcgacgacgg cgagatggcc accctcaagg ccgacgactt ccgcacctac
    19561 accaccgagg gcacccgcac cacgtcggag cccaccaccg tggagtggga ggccgcctcc
    19621 tacgacatgg gcggccacga cacctacatg cacaaggaga tccacgagca ggccgaggcc
    19681 gtggaccgcg tgctgcgcgg ccggatcgac gaccgcttct ccaccgtgca cctcggcggc
    19741 ctcaacctgg acgcccgcga cgcgcgcgcc gtgcgccgcg tgaagatcct gggctgcggc
    19801 acctcgtacc acgcgggcca gatcggcgcc cagatgatcg aggagctggc ccgcatcccc
    19861 gcggacgccg agccggcctc cgagttccgc taccgcaacg cggtcgtcga ccccgacacc
    19921 ctgtacatcg ccgtctccca gtccggcgag acctacgacg tgctggccgc cgtgcaggag
    19981 ctgaagcgca agggcgcccg cgtcctcggc atcgtcaacg tcgtgggctc ggcgatcgcc
    20041 cgcgaggccg acggcgggat gtacgtgcac gccggccccg aggtctgcgt ggtgtcgacc
    20101 aagtgcttca ccaacacctg cgtcgccttc gcgctgctcg ccctgcacct gggccgcacc
    20161 cgcgacctct ccgtccgcga cggcaagcgg atcatcgagg ggttgcgcaa gctgcccgcg
    20221 cagatcgagg agatgctgaa gcaggaggag gacgtcaaga agctggccgc gcagtacgcc
    20281 gaggcccgct cgatgctctt catcggccgg gtgcggggct acccggtcgc ccgcgaggcc
    20341 tccctgaagc tcaaggaggt ctcctacatc cacgccgagg cctacccggc ctccgagctg
    20401 aagcacggcc cgctcgccct gatcgagccg gccctgccga ccgtcgcgat cgtgccggac
    20461 gacgacctgc tggagaagaa ccgcgcggcc ctggaggaga tcaaggcccg cagcggtcag
    20521 atcctcgctg tggcccacca ggagcaggag aaggccgacc acacgatcgt cgtcccgaag
    20581 aacgaggacg agctggaccc gatcctcatg ggcatcccgc tccagctcct cgcgtaccac
    20641 acggctctgg ccctgggccg ggacatcgac aagccccgca acctcgccaa gtccgtgacg
    20701 gtggagtagc cccgtcccgc ggggtcaggg gatgacgacc acgggccgct tcgcgcgctt
    20761 ggcgaggcgg cccgcgacgg agccgaagag gcggccgacc agtccgtggc tggagccgac
    20821 gacgatggcg tcggcctcgt actcccgccc cacctcttcg agctcgtggc agatgtcgcc
    20881 gccgcgctcg accaggatcc aggacacctc ggcgaggtag tccgcgcacg ccagctccag
    20941 accgagcacc tcggtgcggt ggtcgggcac gtcgacgaag accgggggtt cgcagccggc
    21001 ccacacggtg gtgggcagcc ggttggcgac atgcacgatg accaggccgg agcccaaccg
    21061 cgaggccatg ccgatggcgt aggcgagggc gcgctcgctg gacgtggagc cgtcgaagcc
    21121 gacgacgaca ccgtgcttga aggctgggtc gcacgactgg cgtggctctt cggccgccag
    21181 gggctcggcc gccgtaggtt cggcgacggg ccgcttgcgg tccgcgggtt cgaagaattc
    21241 gtgaccggcc atggctgtct cggcgttttt atcctctatg ggggacaaca gtgtgcggcg
    21301 gagctgtgtc cgggaatggt cttcccaacc ccataccccc aagggtacgg cggcacgcct
    21361 ccttcgccca gatctcgcag ggggtccccg cgggattcac cggagcatgc ccgagagggc
    21421 gcccgtaacg caatggttgc tgctctgtac aggcggtttg cacaggattc aactgtccgt
    21481 gaccggtcgt gtcccgtcgt gaccgaggcg gctcacgggc gttgatcccc gtgccgccac
    21541 cccagggagc acccgtgtca ggaccgcacc gtcccgccga cccgacgtcc ggcacacccg
    21601 accgggacgg cgtcaccgat ctcgtccgct gggcggcgtt cagctgcttc ctcgtcccgg
    21661 tggcgctcct ctggtacggc gcctccttcg cgggcgccgc cggcacggcc ttcggcctgg
    21721 ccgccgtcac cgccgcgtgc cgtctgctgc tgcggcgttc cgagcgggtc gcggcccggc
    21781 agcgggcgcg cggacgtggg cggcaggcac gcaggggcgg gcggcacgct ggggaaaaag
    21841 caccggtcga ctgaccggtt tccgcgcaca gttccgcttc ttttcagcca acttccgcac
    21901 gtggctcatc catgcccctc accaccccca aacccccgtt ccacctgcac ggacagggtc
    21961 tcgggccccc ctcgcaccct acggggattg gccactgaca caaggcgtac ttcccagggg
    22021 cgcccgggag tgcaacgctt cgtgatcgac tgcttcacgc caagttgcca tgtcgacaat
    22081 gtcccaagtg ccgaaccggc cacctcggcg cggcgggaca cagtagattc gatcttgacc
    22141 gtctacggcg ggggactcgt gcaggaccga ggggaaacgt gttggagcga cagacccgaa
    22201 gggtgaaggg cgccgcgacc accgaggggg gcttagcagt atgagccacg actccaccgc
    22261 cgcgccggaa gccgcggccc ggaagctgtc cgggcgacgc cgcaaggaga tcgtcgcggt
    22321 gctgctgttc agcggcggcc ccatcttcga gagttccata ccgctgtcgg tgttcgggat
    22381 cgaccgccag gacgccggcg tgccgcgcta ccggctgctg gtgtgcgccg gcgaggacgg
    22441 cccgctgcgg accacggggg gcctggaact caccgcgccg cagggactgg aggcgatctc
    22501 gcgcgcgggc acggtcgtcg tgccggcctg gcggtcgatc acctcgccgc cgccggagga
    22561 agcactcgac gcactgcgca gggcgcacga ggagggggcg cgcatagtcg gactgtgcac
    22621 gggcgccttc gtcctcgcgg cggccggcct gttggacggc cgccccgcca ccacgcactg
    22681 gatgtacgcg ccgacgctgg ccaagcgcta tccgtcggtg cacgtcgacc cgcgcgaact
    22741 cttcgtggac gacggcgacg tgctgacgtc cgccggcacc gcggccggga tcgacctgtg
    22801 cctgcacatc gtgcgcacgg accacggcaa cgaggcggcc ggtgcgctgg cccgccggct
    22861 ggtggtcccc ccgcgccgca gcggcggcca ggagcgctac ctcgacaggt ctttaccgga
    22921 ggagatcggc gccgacccgc tcgccgaggt cgtcgcctgg gcgctggagc acctccacga
    22981 gcagttcgac gtggagacgc tggccgcgcg cgcctacatg agccgccgca ccttcgaccg
    23041 ccggttccgc tcgctgacgg gcagcgcccc gctccagtgg ctgatcaccc agcgggtgct
    23101 ccaggcgcag cgcctgctgg agacgtcgga ctactcggtg gacgaggtcg ccgggcgctg
    23161 cggcttccgc tccccggtgg ccctgcgcgg ccacttccgc cgccagctgg gctcgtcccc
    23221 ggccgcctac cgggcggcct accgggcgcg ccgtccccag ggcgaccgcc agccggaccc
    23281 ggacaccgca gccgcgggcg ccacccgccc gctgcccccg tccgacccgc cggcctccct
    23341 cgccccggag aacgcggtcc cgttccagac ccgccgcacc gccaccccga tgccggcggg
    23401 cgcggccagc gtcccgggcc agcgcagcgc gccgtgaggt gagcagacgg ctccctcgaa
    23461 cgccggacgg gccggagcgt gcccgtccgg cgttcccgtc cggtgccggg cggggcacac
    23521 tcagcccgtc cggcgttccc gtccgatgcc gggcagggca cactcagccc cttcggcgtt
    23581 cccgttcgat gccgggcggg gcacactcag ccccttcggc gttcccgtcc gatgccgggc
    23641 agggcaattc agcccgtccg gcgtttgagg acgaggcccg ttcagggccg aagcgggggt
    23701 tcgggggcgg ccgcccccgt gacgcccgca ccgacgccgg gggcccgata gacaggcgcc
    23761 caccgtaaag tggcccgcat gaacgatcgc atggtgtgga tcgactgcga gatgaccggc
    23821 ctctcgctgt ccgacgacgc gctcatcgag gttgccgccc tcgtcaccga ctccgagctg
    23881 aacatcctcg gcgaaggcgt cgacatcgtg atccgcccgc cggagcgggc cctggagacg
    23941 atgccggagg tggtgcgcga gatgcacacc gcgtccgggc tgctcgcgga gctggacggc
    24001 ggcacgaccc tggcggacgc cgaggcccag gtcctggcct atgtgcggga gcacgtgaag
    24061 gagccgggca aggccccgct gtgcggcaac tcggtcggca ccgaccgcgg cttcctgctg
    24121 cgggacatgg cgacgctgga gggctacctc cactaccgga tcgtcgacgt ctcctcgatc
    24181 aaggagctgg cccgccgctg gtacccgcgg gcgtacttca acagcccgga gaagaacggc
    24241 aaccaccggg cgctcgccga catccgcgag tccatcgccg aactccgcta ctaccgggag
    24301 gcggtcttcg tcccgcagcc cggccccgac tccgacacgg cccgggcgat cgccgcgaag
    24361 cacgtcgtat ccgccggtta ggggcgcggg cccgccgggc ggccgcgtcc ggaaagccgg
    24421 gcgcgagcac cccttcggac cctgtacact ttttctcagc cggtcgggaa acccgccatg
    24481 cgggattcga gcaccggcct tggtgggtgt agctcagctg gtagagcacc tggttgtggt
    24541 ccaggatgcc gcgggttcaa gtcccgtcac tcaccctgat acgtcagccg gtgaccttcg
    24601 cgaaggtcac cggctgacgg cgttccacaa gcttccggtg ctccggaagc ttccggcgtt
    24661 ccgagagcct ccggcagccg gcccccgccc agagcccgcg ccgcccctcc cgtacgagca
    24721 gcaccagcag gtacaggccc cccgacacac atcgtgacgg cgccgtacgg acccggcgag
    24781 gtcgacggac gtgccgtggc cgtcgatggt ggcggcccgg gcgtcgtcgg cgccgacggt
    24841 tgccgggggt gcaccccgtc ggcggtcgcc cggggggtga cccccgtcag cggttgccaa
    24901 agggcgtacc ccgccggcgg ttgccggggg gcgcacaccc tcttacgacg acctgcgctc
    24961 caccagttcc gtcgccagca ccacctggtg gcgttccagg ccgcgcgagg cggccgggcg
    25021 gcggtcggcg atctcggtca gcagcaggtc gatcatcgcg cggcccatct cctcgatggg
    25081 ctggcgcacg ctggtcagcg gcggctccat gtggcgggcg atggccgagt cgtcgtagcc
    25141 gaccagcgcc acgtcgtccg ggatgcgccg gcccgcctcg cgcaggacct gcccggcgcc
    25201 cgccgcggtg acgtcggagg cggcgaagac cgcgtccacg tcggggtggc ggcgcagcag
    25261 ctccgccatc gcgcggcgtc cgccctcctc ggtgaagtcg cccggctcga tcagtccctc
    25321 gtccacctcg tggcccgcct cgcgcagggc gtcgcggtag ccgtcgacgc gtcgctgcgc
    25381 gccgtagacg gcgaggtgac cggtgatgtg ggcgacgcgg ccgcgccctc gggacagcag
    25441 gtgctcgacg gccgagcggg cgccgccata gttgtccgag tccaccgacg ccagcggttc
    25501 cgcggccgag cgcgggccgc tgatcaccgc ggggatctcc agctgggtca gcaggtcggg
    25561 cagcgggtcg tcggcgtgca ccgagaccag caggacgccg tccacccggt gcgccgccag
    25621 atactgggcg agccgctccc gctcccggtc gctgcccgcg aatatcagca gcagctgcat
    25681 ctcggtctcg gacagctcgg agccgacgcc cttcagcatg tccgagaagt acggctccgc
    25741 gaagaaccgc gtctccggct ccggcaccac cagggcgatc gcgtccgtgc ggttggccgc
    25801 cagcgctcgg gccgccgtgt tcgggacgta cccgagttcc gcgaccgccg cctcgacggc
    25861 cgcccgggtc gcgtcgctga cccgcggcga gccgttgatc acgcgggaga ccgtgccgcg
    25921 gccgacgccc gcgcgtgccg ccacctcttc gagggtgggc cggccaccgc tccgaccacg
    25981 cactccgtgg cttgccatcg gctccgcctc ccgtcgtcac ccccgcactc tgcggctggc
    26041 ctggaattta acaggccggt cgggtgtaat gaccgactcc ggcccctccc ccgccgtacg
    26101 ggaggtgtct cagcgccgct cgcaacgtcc agttaacagg ccgataactg aacgcaattc
    26161 gtcgcgtccg ttcccttgac acccccgccc ggaccgacga ctcttcaaca catcacttgt
    26221 gggagcgctc ccacactacc tggcacatac acatcccgca cgttccccgc ccgagccgca
    26281 gcaacgaacg aaacacatga agcagcgggt ccaaccatgt agttggccgg ggggtcggca
    26341 cgtcagggca acaggaggac gcaatgcgag cagcacgcag aggatcggcc cgcagggtgg
    26401 tggtcatggc ggccatcgcg tcgctgggcg ccgggctgct ggccggctgt gccgacgacg
    26461 ggaacgacga ggacagctcg tcgtcgggcg acagcagcgg caagaccacg atcaccctcg
    26521 gtctgttcgg gacgatgggc ttcaaggaag ccggtctcta cgacgagtac gagaagctca
    26581 acccggacat caacatcgag gagaacgtca ccgagcggaa cgagaactac taccccgccc
    26641 tggtgaacca cctcaccacc aacagcggcc tccaggacgt gcaggcgata gaggtcggca
    26701 acatcgccga ggtcgtcgcc acccaggcgg acaagttcga ggacatgtcc aaggccgcgg
    26761 gcgtccagaa ggccaactgg ctcgactgga agtggcagca ggccaccacc aaggacggcg
    26821 ccacgatcgg cctcggcacc gacatcggcc cgatggccat ctgctaccgc aaggacctgt
    26881 tcgagaaggc cggcctgccg accgaccgcg aagaggtctc caagctgtgg gccggtgact
    26941 ggaacaagtt catcgaggcc ggcgagaagt acaagaaggg ggccggcaag gacacctact
    27001 tcatggactc ccccggcggt ctgatcaacg ccatcctcag cagtgaggac gagaagttct
    27061 acgacgcctc gggcaaggtc atctacaaga ccaacccggc cgtcaaggac gccttcgacc
    27121 tgaccgccga ggcggccgag aaggggctgg tccagtcgca gacccagttc cagccggcct
    27181 gggaccagac catttccaac agcctgttcg ccaccgtcgc ctgcccgccg tggatgctcg
    27241 gcaccatcaa ggccaagtcc cagccggact ccgccggcaa gtgggacgtc gcccaggccc
    27301 cgaaggccgg caactggggc ggcaccttcc tgggcgtgcc caagagcggc aagcacgtga
    27361 aggaggccca gaagctggtc acctggctga ccgcgcccga gcagcaggcc aagctcttct
    27421 ccaagatggg cagcttcccg agcgcgcccg ccgcgtacaa gctcccccag gtgaccggcg
    27481 gcaagaacga catgaccggt gacgcgccga tcggcgagct gttcgccaag gccgcggagc
    27541 agatcccgac ccaggtgatc ggcccgaagg accagatcgt ccagcagggt ctgaccgaca
    27601 acggcgtcat cctcgtcacc cagggcaagt cggccgagga cgcgtgggac aacgccgtga
    27661 agaccatcga caacaacctg gagaagtgac cggaatgacc acccggcacg acaccgccgc
    27721 gtcccccgtc aaggggggcg cggccccggg ccgcccgccc ggcggcaggg cgtccgcgga
    27781 ggcggaccgc aggaagcggg ccaagctctc ccgccgctgg cagcgggaca tgcgctggag
    27841 cccgtacgcg ttcgtctcgc cgttcttcct gctcttcctc gccttcggcc tgttcccgct
    27901 gatctacacc ggctgggcct cgctgcacac ggtggagctg accgcgccca ccgacatgca
    27961 gtggacgggg ctggacaact acacccggat cttcgacgac gagttcttct ggaacgccgc
    28021 gaagaacaca ctgtggatcg gcgtcatctc gacggtgccg cagctgctga tggcgatggg
    28081 cctcgcgcac atcctcaact acaagctgcg cgcctcgacc ttctaccggg tcgtgatgct
    28141 ggcgccgtac gcgacgtcga tcgccgcggc ctcgctggtc ttcgtgctgc tcttcggccg
    28201 ggactacggc atgatcaact gggtcctcga cctggtgggc ctggacaaga tcgactggca
    28261 gaacggctcg tggtcgtcca agttcgccgt gtccacgatc gtcatctggc gctggaccgg
    28321 ctacaacgcg ctgatctacc tggccgcgat gcaggcgatc ccgcaggacc tgtacgagtc
    28381 ggcggcgctg gacggcgcca gccgctggcg gcagttcatc cacgtcacgc tgccctcgct
    28441 gcgtcccacg atcctgttca cggtcgtcgt gtcgaccatc ggcgcctcgc aggtcttcgg
    28501 cgagccgctg ctcttcgacg ccaacaaggg cgcctcgggc ggctcccagc accagttcca
    28561 gacgctcggc ctgtacctgt acgagcaggg ctgggtcaac cagcacctgg gccgcgcctc
    28621 cgcgatcgcc tgggcgatgt tcctgatcct gatcgtgatc ggggtcctca acgccgtcat
    28681 ctcgcgccgg ctgcgcgcca gtagttaagg agaaccggcc gtgacgacga ccatgacgaa
    28741 acccccggcc gacgcggcac ccgagccgcc ccggcggggc cgacgacgtt ccaaggcatc
    28801 ccgggccggt ggcacgctgc acgccgggcc ggtcgcctac atcatcctcg ccctgttcac
    28861 catcggctcg ctgttcccgc tggtgtggac ggcgatcgcc gcctcgcgcg acaaccagcg
    28921 gctcgcccag acaccgccgc ccctctggtt cggcggcaac ctgttcgaca agctcgagat
    28981 cgcctggaac gacgccaacc tcggcgaggc gttcctcaac accaccatcg tggccgggat
    29041 ctcggcgtgc accatcgtct tcctgtcgac ggtcgccggg ttcgccttcg ccaagctgcg
    29101 cttccgcggg cgcaacgcgc tgatgctgat cgtcgtcggc acgatgatgg tgccgccgca
    29161 gctcagcatc atcccgctgt acatgatggt cgcgaagctg gactggtccg accagttgca
    29221 ggcggtgatc ctgccgtccc tggtgaacgc gttcggcgtg ttcttcatgc ggcagtacct
    29281 gctccaggcg ctgcccgacg agatcatcga ggccgcgcgc gtggacggcg ccagcagctg
    29341 gcgtgtgatg tggcacgtgg tgttcccggc ggcgcggccc gcgatggccg tgctcggcat
    29401 gctgatgttc gtgcagtcct ggaacgactt cctgtggccg ttcctggtgc tgacgcagaa
    29461 cggcagcccg accgtgcagg tcgcactcgc cggactgggc cgcggctaca ccccggacca
    29521 gtccctgatc atggccggtg cgctgctggg cacgctgccg ctgctgctgg tgttcgcgat
    29581 cttcggcaag cagatcgtgg gcggcatcat gcagggcgcc gtcaagggct gacccctcac
    29641 cttcggggcc gggccaccgc cccggccccc ctttcccccc tcgtccttct tactcgtcgg
    29701 tccagcgcgt cggtcctccg gccggtcccc ccgggacccg cccggaccgc cacgacctgc
    29761 tatgggagcg cttccatgct tgagtccg
//
