LOCUS       NC_003888              41125 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    .
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2023-11-22 14:16:39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1257624
            Orig. end    :: 1298749
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..41125
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21125]"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21125
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     cand_cluster    1..41125
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..41125
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="6"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     regulatory      579..583
                     /regulatory_class="ribosome_binding_site"
     gene            594..1619
                     /db_xref="GeneID:1096609"
                     /gene_synonym="SCG11A.17"
                     /locus_tag="SCO1186"
     CDS             594..1619
                     /codon_start=1
                     /db_xref="GeneID:1096609"
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 367.4; E-value: 1.1e-111)"
                     /gene_kind="regulatory"
                     /gene_synonym="SCG11A.17"
                     /locus_tag="SCO1186"
                     /note="SCG11A.17, probable lacI-family transcriptional
                     regulator, len: 341 aa; similar to TR:CAB46346
                     (EMBL:AJ009798) Streptomyces reticuli regulatory protein
                     CebR, 350 aa; fasta scores: opt: 1241 z-score: 1440.4 E():
                     0; 57.9% identity in 347 aa overlap and to SW:PURR_ECOLI
                     (EMBL:J04212) Escherichia coli purine nucleotide synthesis
                     repressor PurR, 340 aa; fasta scores: opt: 587 z-score:
                     684.5 E(): 9.5e-31; 35.7% identity in 336 aa overlap and to
                     Streptomyces coelicolor SC4G6.23; fasta scores: opt: 989
                     z-score: 952.6 E(): 0; 53.8% identity in 316 aa overlap.
                     Contains matches to Pfam entries PF00356 lacI, Bacterial
                     regulatory proteins, lacI family and PF00532
                     Peripla_BP_like, Periplasmic binding proteins and LacI
                     family and to Prosite entry PS00356 Bacterial regulatory
                     proteins, lacI family signature. Contains also a possible
                     helix-turn-helix motif at residues 10..31 (+6.13 SD)"
                     /product="LacI family transcriptional regulator"
                     /protein_id="NP_625476.1"
                     /transl_table=11
                     /translation="MGRQRPGTPTLEEVAARAGVGRGTVSRVVNNAAGVRDSTRRAVQR
                     AIAELGYVPNLAARSLAGHRADAVALVMTEPDWRLFGEPFFTEIVHAVGDALTDTPFQL
                     LLTLVRTDTERRRFVEYARGGRVDGVLLMSVHAEDPLPDMLADAGLPTVMLGRRSGEEC
                     VTYVDADNAGGARGAVTYLLDAGRRRIGAISGPLDMYVAQCRLRGYREALEPAGVAAGA
                     SLVVEGSDFTEESGHRAMTELLARHPDLDAVFAASDTLAAGALNALRAAGRRVPQDVAV
                     IGFDDFHPARPTDPPLTTVRQPLEEIGRTMVRLLLEEMEDAPVAWRHVILRTELVVRDS
                     A"
     misc_feature    612..695
                     /gene_synonym="SCG11A.17"
                     /locus_tag="SCO1186"
                     /note="Pfam match to entry PF00356 lacI, Bacterial
                     regulatory proteins, lacI family, score 30.70, E-value
                     3.8e-07"
     PFAM_domain     621..758
                     /aSDomain="LacI"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00356.24"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0006355"
                     /description="Bacterial regulatory proteins, lacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1186_0178"
                     /evalue="4.50E-15"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO1186"
                     /locus_tag="SCO1186"
                     /protein_end="55"
                     /protein_start="9"
                     /score="55.3"
                     /tool="antismash"
                     /translation="TLEEVAARAGVGRGTVSRVVNNAAGVRDSTRRAVQRAIAELGYVP
                     N"
     misc_feature    624..680
                     /gene_synonym="SCG11A.17"
                     /locus_tag="SCO1186"
                     /note="PS00356 Bacterial regulatory proteins, lacI family
                     signature"
     misc_feature    786..1526
                     /gene_synonym="SCG11A.17"
                     /locus_tag="SCO1186"
                     /note="Pfam match to entry PF00532 Peripla_BP_like,
                     Periplasmic binding proteins and LacI family., score
                     116.60, E-value 4.6e-31"
     PFAM_domain     1128..1613
                     /aSDomain="Peripla_BP_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13377.9"
                     /description="Periplasmic binding protein-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1186_0179"
                     /evalue="1.60E-35"
                     /label="SCO1186"
                     /locus_tag="SCO1186"
                     /protein_end="340"
                     /protein_start="178"
                     /score="122.9"
                     /tool="antismash"
                     /translation="VTYLLDAGRRRIGAISGPLDMYVAQCRLRGYREALEPAGVAAGAS
                     LVVEGSDFTEESGHRAMTELLARHPDLDAVFAASDTLAAGALNALRAAGRRVPQDVAVI
                     GFDDFHPARPTDPPLTTVRQPLEEIGRTMVRLLLEEMEDAPVAWRHVILRTELVVRDS"
     misc_feature    complement(1632..1646)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.98"
                     /tool="antismash"
     misc_feature    1633..1647
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.98"
                     /tool="antismash"
     misc_feature    complement(1752..1766)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     misc_feature    1753..1767
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 30.11"
                     /tool="antismash"
     misc_feature    complement(1778..1792)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.56"
                     /tool="antismash"
     misc_feature    1779..1793
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.19"
                     /tool="antismash"
     regulatory      1825..1828
                     /regulatory_class="ribosome_binding_site"
     gene            1837..2982
                     /db_xref="GeneID:1096610"
                     /gene_synonym="celB; SCG11A.18"
                     /locus_tag="SCO1187"
     CDS             1837..2982
                     /codon_start=1
                     /db_xref="GeneID:1096610"
                     /gene_synonym="celB; SCG11A.18"
                     /locus_tag="SCO1187"
                     /note="SCG11A.18, celB, cellulase B precursor, len: 381 aa;
                     identical to TR:Q54331 (EMBL:U04629) Streptomyces lividans
                     cellulase precursor, celB, 381 aa and similar to
                     SW:GUX_CELFI (EMBL:M15824) Cellulomonas fimi
                     exoglucanase/xylanase precursor [includes: exoglucanase (EC
                     3.2.1.91) (exocellobiohydrolase)
                     (1,4-beta-cellobiohydrolase) (beta-1,4- glycanase Cex);
                     endo-1,4-beta-xylanase B (EC 3.2.1.8) (xylanase B) Cex or
                     XynB, 484 aa; fasta scores: opt: 422 z-score: 450.5 E():
                     1e-17; 48.8% identity in 123 aa overlap. Contains two
                     matches to Pfam entries PF01670 Glyco_hydro_12, Glycosyl
                     hydrolase family 12 and PF00553 CBD_2, Cellulose binding
                     domain and match to Prosite entry PS00561 Cellulose-binding
                     domain, bacterial type. Contains also possible signal
                     peptide sequence"
                     /product="cellulase B"
                     /protein_id="NP_625477.1"
                     /transl_table=11
                     /translation="MRTLRPQARAPRGLLAALGAVLAAFALVSSLVTAAAPAQADTTIC
                     EPFGTTTIQGRYVVQNNRWGSTATQCVTATDTGFRVTQADGSAPTNGAPKSYPSVFNGC
                     HYTNCSPGTALPVRLDTVSAAPSSISYGFVDGAVYNASYDIWLDPTARTDGVNQTEIMI
                     WFNRVGPIQPIGSPVGTASVGGRTWEVWSGGNGSNDVLSFVAPSAISGWSFDVMDFVRA
                     TVARGLAENDWYLTSVQAGFEPWQNGAGLAVNSFSSTVETGTPGGTDPGDPGGPSACAV
                     SYGTNVWQDGFTADVTVTNTGTAPVDGWQLAFTLPSGQRITNAWNASLTPSSGSVTATG
                     ASHNARIAPGGSLSFGFQGTYGGAFAEPTGFRLNGTACTTV"
     misc_feature    1846..1848
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    1900..1902
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     PFAM_domain     2002..2619
                     /aSDomain="Glyco_hydro_12"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01670.19"
                     /db_xref="GO:0000272"
                     /db_xref="GO:0008810"
                     /description="Glycosyl hydrolase family 12"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1187_0180"
                     /evalue="2.10E-83"
                     /gene_ontologies="GO:0000272: polysaccharide catabolic
                     process"
                     /gene_ontologies="GO:0008810: cellulase activity"
                     /label="SCO1187"
                     /locus_tag="SCO1187"
                     /protein_end="261"
                     /protein_start="55"
                     /score="279.6"
                     /tool="antismash"
                     /translation="RYVVQNNRWGSTATQCVTATDTGFRVTQADGSAPTNGAPKSYPSV
                     FNGCHYTNCSPGTALPVRLDTVSAAPSSISYGFVDGAVYNASYDIWLDPTARTDGVNQT
                     EIMIWFNRVGPIQPIGSPVGTASVGGRTWEVWSGGNGSNDVLSFVAPSAISGWSFDVMD
                     FVRATVARGLAENDWYLTSVQAGFEPWQNGAGLAVNSFSSTVE"
     misc_feature    2167..2619
                     /gene_synonym="celB; SCG11A.18"
                     /locus_tag="SCO1187"
                     /note="Pfam match to entry PF01670 Glyco_hydro_12, Glycosyl
                     hydrolase family 12, score 293.70, E-value 2.3e-84"
     misc_feature    2671..2970
                     /gene_synonym="celB; SCG11A.18"
                     /locus_tag="SCO1187"
                     /note="Pfam match to entry PF00553 CBD_2, Cellulose binding
                     domain, score 152.60, E-value 3.3e-43"
     PFAM_domain     2671..2970
                     /aSDomain="CBM_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00553.22"
                     /db_xref="GO:0004553"
                     /db_xref="GO:0005975"
                     /db_xref="GO:0030246"
                     /description="Cellulose binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1187_0181"
                     /evalue="4.80E-31"
                     /gene_ontologies="GO:0004553: hydrolase activity,
                     hydrolyzing O-glycosyl compounds"
                     /gene_ontologies="GO:0005975: carbohydrate metabolic
                     process"
                     /gene_ontologies="GO:0030246: carbohydrate binding"
                     /label="SCO1187"
                     /locus_tag="SCO1187"
                     /protein_end="378"
                     /protein_start="278"
                     /score="107.2"
                     /tool="antismash"
                     /translation="CAVSYGTNVWQDGFTADVTVTNTGTAPVDGWQLAFTLPSGQRITN
                     AWNASLTPSSGSVTATGASHNARIAPGGSLSFGFQGTYGGAFAEPTGFRLNGTAC"
     misc_feature    2809..2850
                     /gene_synonym="celB; SCG11A.18"
                     /locus_tag="SCO1187"
                     /note="PS00561 Cellulose-binding domain, bacterial type"
     regulatory      3220..3224
                     /regulatory_class="ribosome_binding_site"
     gene            3230..4324
                     /db_xref="GeneID:1096611"
                     /gene_synonym="celS2; SCG11A.19"
                     /locus_tag="SCO1188"
     CDS             3230..4324
                     /codon_start=1
                     /db_xref="GeneID:1096611"
                     /gene_synonym="celS2; SCG11A.19"
                     /locus_tag="SCO1188"
                     /note="SCG11A.19, celS2, cellulose binding protein len: 364
                     aa; highly similar to TR:AAD27623 (EMBL:AF126376)
                     Streptomyces viridosporus cellulose binding protein CelS2,
                     358 aa; fasta scores: opt: 2109 z-score: 2160.9 E(): 0;
                     81.9% identity in 364 aa overlap and to SW:GUNA_MICBI
                     Microbispora bispora endoglucanase A precursor (EC 3.2.1.4)
                     (endo-1,4-beta-glucanase) (CELLULASE) CelA, 456 aa; fasta
                     scores: opt: 350 z-score: 363.9 E(): 6.8e-13; 30.6%
                     identity in 278 aa overlap. Contains match to Pfam entry
                     PF00553 CBD_2, Cellulose binding domain. Contains also
                     possible signal peptide sequence"
                     /product="cellulose binding protein"
                     /protein_id="NP_625478.1"
                     /transl_table=11
                     /translation="MVRRTRLLTLAAVLATLLGSLGVTLLLGQGRAEAHGVAMMPGSRT
                     YLCQLDAKTGTGALDPTNPACQAALDQSGATALYNWFAVLDSNAGGRGAGYVPDGTLCS
                     AGDRSPYDFSAYNAARSDWPRTHLTSGATIPVEYSNWAAHPGDFRVYLTKPGWSPTSEL
                     GWDDLELIQTVTNPPQQGSPGTDGGHYYWDLALPSGRSGDALIFMQWVRSDSQENFFSC
                     SDVVFDGGNGEVTGIRGSGSTPDPDPTPTPTDPTTPPTHTGSCMAVYSVENSWSGGFQG
                     SVEVMNHGTEPLNGWAVQWQPGGGTTLGGVWNGSLTSGSDGTVTVRNVDHNRVVPPDGS
                     VTFGFTATSTGNDFPVDSIGCVAP"
     PFAM_domain     3332..3904
                     /aSDomain="LPMO_10"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03067.18"
                     /description="Lytic polysaccharide mono-oxygenase,
                     cellulose-degrading"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1188_0182"
                     /evalue="4.40E-38"
                     /label="SCO1188"
                     /locus_tag="SCO1188"
                     /protein_end="225"
                     /protein_start="34"
                     /score="131.9"
                     /tool="antismash"
                     /translation="HGVAMMPGSRTYLCQLDAKTGTGALDPTNPACQAALDQSGATALY
                     NWFAVLDSNAGGRGAGYVPDGTLCSAGDRSPYDFSAYNAARSDWPRTHLTSGATIPVEY
                     SNWAAHPGDFRVYLTKPGWSPTSELGWDDLELIQTVTNPPQQGSPGTDGGHYYWDLALP
                     SGRSGDALIFMQWVRSDSQENFFSCSDV"
     misc_feature    4022..4282
                     /gene_synonym="celS2; SCG11A.19"
                     /locus_tag="SCO1188"
                     /note="Pfam match to entry PF00553 CBD_2, Cellulose binding
                     domain, score 74.40, E-value 2.4e-20"
     PFAM_domain     4022..4288
                     /aSDomain="CBM_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00553.22"
                     /db_xref="GO:0004553"
                     /db_xref="GO:0005975"
                     /db_xref="GO:0030246"
                     /description="Cellulose binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1188_0183"
                     /evalue="4.70E-20"
                     /gene_ontologies="GO:0004553: hydrolase activity,
                     hydrolyzing O-glycosyl compounds"
                     /gene_ontologies="GO:0005975: carbohydrate metabolic
                     process"
                     /gene_ontologies="GO:0030246: carbohydrate binding"
                     /label="SCO1188"
                     /locus_tag="SCO1188"
                     /protein_end="353"
                     /protein_start="264"
                     /score="71.9"
                     /tool="antismash"
                     /translation="CMAVYSVENSWSGGFQGSVEVMNHGTEPLNGWAVQWQPGGGTTLG
                     GVWNGSLTSGSDGTVTVRNVDHNRVVPPDGSVTFGFTATSTGND"
     gene            4497..4922
                     /db_xref="GeneID:1096612"
                     /gene_synonym="SCG11A.20"
                     /locus_tag="SCO1189"
     CDS             4497..4922
                     /codon_start=1
                     /db_xref="GeneID:1096612"
                     /gene_synonym="SCG11A.20"
                     /locus_tag="SCO1189"
                     /note="SCG11A.20, unknown, len: 141 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_625479.1"
                     /transl_table=11
                     /translation="MTPAQRAFERLQAWPDLSAGPASCGTGRALCSVRDEIVHFHSDRD
                     VDLHLTHRAIQRFRYDLGGSTAIRLVPGSRWVTVHLDCDADVDLLLSLVSIALKAHQSR
                     PPADLAPGPPGPTALSAPPGCNFHRVTVLPRAAAGEA"
     PFAM_domain     4506..4793
                     /aSDomain="DUF5519"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF17648.4"
                     /description="Family of unknown function (DUF5519)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1189_0184"
                     /evalue="3.90E-23"
                     /label="SCO1189"
                     /locus_tag="SCO1189"
                     /protein_end="99"
                     /protein_start="3"
                     /score="81.4"
                     /tool="antismash"
                     /translation="AQRAFERLQAWPDLSAGPASCGTGRALCSVRDEIVHFHSDRDVDL
                     HLTHRAIQRFRYDLGGSTAIRLVPGSRWVTVHLDCDADVDLLLSLVSIALK"
     gene            complement(4885..6486)
                     /db_xref="GeneID:1096613"
                     /gene_synonym="SCG11A.21c"
                     /locus_tag="SCO1190"
     CDS             complement(4885..6486)
                     /codon_start=1
                     /db_xref="GeneID:1096613"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 414.4; E-value:
                     7.9e-126)"
                     /gene_kind="transport"
                     /gene_synonym="SCG11A.21c"
                     /locus_tag="SCO1190"
                     /note="SCG11A.21c, probable export protein, len: 533 aa;
                     similar to SW:TCMA_STRGA (EMBL:M80674) Streptomyces
                     glaucescens tetracenomycin C resistance and export protein
                     TcmA, 538 aa; fasta scores: opt: 1520 z-score: 1545.7 E():
                     0; 45.7% identity in 523 aa overlap"
                     /product="export protein"
                     /protein_id="NP_625480.1"
                     /transl_table=11
                     /translation="MPSTSVDHPAVPAAEPAPAPGAAGRLRSNPWLTLLAVAFGLFMVQ
                     LDGSVVAIANPEIGSDLHASTAQLQWVTNAYLLALAATLILGGKLGDRFGRRTYYLVGV
                     AGFTLASIAIGLAGSIEGVVAFRALQGAFGGLLMPNTLGLLRSVFPPKKFGMAVGIWAM
                     VSAVATALGPIVGGLLVEHVDWESVFYVNAPIGVAAIAFGALVLPQSRNAAGRERFDIP
                     GLVLLALGLLAVVFGVVKGETWGWTSAGTLGAVAAGLLLLLVFGRYETRVEHPLLPMRL
                     FRSRALTIGAIVTALNFFVMLGVIFFVMLYLQNVRGFTPVEAGVRTLPLSLASLVASPL
                     GAALTQRFGPRLTMPLGMLLQAASCFGMLTWQTDSAYATMWPPFIALGLGVGMVMAASS
                     DAIVGNAPVRDGGVAGGLQATTLQIGGALGTSVLVSLISAKVDATLTGELTGAGVPPAV
                     AHGLQEARDAVAMGVAPVSGEMPAGLRAAVVEGSGQAFMNGVHVAVVVTGALCVFGAAL
                     AAAGLRPPRPRHAEAP"
     aSDomain        complement(4939..6390)
                     /aSDomain="TIGR00711"
                     /aSTool="tigrfam"
                     /description="efflux_EmrB: drug resistance MFS transporter,
                     drug:H+ antiporter-2 (14 Spanner) (DHA2) family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO1190_0015"
                     /evalue="6.20E-87"
                     /identifier="TIGR00711"
                     /label="SCO1190"
                     /locus_tag="SCO1190"
                     /protein_end="516"
                     /protein_start="32"
                     /score="290.3"
                     /tool="antismash"
                     /translation="TLLAVAFGLFMVQLDGSVVAIANPEIGSDLHASTAQLQWVTNAYL
                     LALAATLILGGKLGDRFGRRTYYLVGVAGFTLASIAIGLAGSIEGVVAFRALQGAFGGL
                     LMPNTLGLLRSVFPPKKFGMAVGIWAMVSAVATALGPIVGGLLVEHVDWESVFYVNAPI
                     GVAAIAFGALVLPQSRNAAGRERFDIPGLVLLALGLLAVVFGVVKGETWGWTSAGTLGA
                     VAAGLLLLLVFGRYETRVEHPLLPMRLFRSRALTIGAIVTALNFFVMLGVIFFVMLYLQ
                     NVRGFTPVEAGVRTLPLSLASLVASPLGAALTQRFGPRLTMPLGMLLQAASCFGMLTWQ
                     TDSAYATMWPPFIALGLGVGMVMAASSDAIVGNAPVRDGGVAGGLQATTLQIGGALGTS
                     VLVSLISAKVDATLTGELTGAGVPPAVAHGLQEARDAVAMGVAPVSGEMPAGLRAAVVE
                     GSGQAFMNGVHVAVVVTGALCVFGAA"
     PFAM_domain     complement(5200..6378)
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07690.19"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1190_0185"
                     /evalue="6.60E-56"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO1190"
                     /locus_tag="SCO1190"
                     /protein_end="429"
                     /protein_start="36"
                     /score="189.9"
                     /tool="antismash"
                     /translation="VAFGLFMVQLDGSVVAIANPEIGSDLHASTAQLQWVTNAYLLALA
                     ATLILGGKLGDRFGRRTYYLVGVAGFTLASIAIGLAGSIEGVVAFRALQGAFGGLLMPN
                     TLGLLRSVFPPKKFGMAVGIWAMVSAVATALGPIVGGLLVEHVDWESVFYVNAPIGVAA
                     IAFGALVLPQSRNAAGRERFDIPGLVLLALGLLAVVFGVVKGETWGWTSAGTLGAVAAG
                     LLLLLVFGRYETRVEHPLLPMRLFRSRALTIGAIVTALNFFVMLGVIFFVMLYLQNVRG
                     FTPVEAGVRTLPLSLASLVASPLGAALTQRFGPRLTMPLGMLLQAASCFGMLTWQTDSA
                     YATMWPPFIALGLGVGMVMAASSDAIVGNAPVRDGGVAGGLQATTLQIGGALG"
     gene            complement(6559..7032)
                     /db_xref="GeneID:1096614"
                     /gene_synonym="SCG11A.22c"
                     /locus_tag="SCO1191"
     CDS             complement(6559..7032)
                     /codon_start=1
                     /db_xref="GeneID:1096614"
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 68.6; E-value: 6.8e-21)"
                     /gene_kind="regulatory"
                     /gene_synonym="SCG11A.22c"
                     /locus_tag="SCO1191"
                     /note="SCG11A.22c, possible marR-family transcriptional
                     regulator, len: 157 aa; low similarity to TR:CAB48917
                     (EMBL:AL096837) Streptomyces coelicolor marR-family
                     transcriptional regulator SCF43A.30c, 169 aa; fasta scores:
                     opt: 125 z-score: 167.7 E(): 0.058; 30.6% identity in 147
                     aa overlap"
                     /product="MarR family transcriptional regulator"
                     /protein_id="NP_625481.1"
                     /transl_table=11
                     /translation="MTDSSTPRRDIDRMASGLAACLPVLHRALDRQVTARYPHPKPPEG
                     QLALLRYVAQHEGVTVREAAEALLMKPNNVSALVSQLVEQGDLERRRDSADKRVAHLHL
                     TATARERVSEVRELETAFIRHALTSLTEGQQGALGSALDALDALTRHLHPGVR"
     misc_feature    complement(6598..6909)
                     /gene_synonym="SCG11A.22c"
                     /locus_tag="SCO1191"
                     /note="Pfam match to entry PF01047 MarR, MarR family, score
                     47.10, E-value 3.8e-10"
     PFAM_domain     complement(6739..6897)
                     /aSDomain="MarR_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF12802.10"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006355"
                     /description="MarR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1191_0186"
                     /evalue="8.70E-11"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO1191"
                     /locus_tag="SCO1191"
                     /protein_end="98"
                     /protein_start="45"
                     /score="41.8"
                     /tool="antismash"
                     /translation="QLALLRYVAQHEGVTVREAAEALLMKPNNVSALVSQLVEQGDLER
                     RRDSADKR"
     gene            7156..7524
                     /db_xref="GeneID:1096615"
                     /gene_synonym="SCG11A.23"
                     /locus_tag="SCO1192"
     CDS             7156..7524
                     /codon_start=1
                     /db_xref="GeneID:1096615"
                     /gene_synonym="SCG11A.23"
                     /locus_tag="SCO1192"
                     /note="SCG11A.23, hypothetical protein, len:122 aa; similar
                     to various hypothetical proteins, e.g. TR:O53744
                     (EMBL:AL021933) Mycobacterium tuberculosis hypothetical
                     17.2 KD protein MTV038.03, 163 aa; fasta scores: opt: 478
                     z-score: 600.7 E(): 4.4e-26; 66.7% identity in 111 aa
                     overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_625482.1"
                     /transl_table=11
                     /translation="MGDTYEETPRVELTPEASLLLRRLREAHGPLMFHQSGGCCDGSAP
                     MCYLAGEFRTGASDILLGELAVDGVEEPVEFWMSRSQYEAWRHTRLIVDVVPGRGSGFS
                     LEAPEGVRFLIRSRVVDV"
     PFAM_domain     7213..7512
                     /aSDomain="DUF779"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05610.14"
                     /description="Protein of unknown function (DUF779)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1192_0187"
                     /evalue="3.70E-47"
                     /label="SCO1192"
                     /locus_tag="SCO1192"
                     /protein_end="119"
                     /protein_start="19"
                     /score="158.7"
                     /tool="antismash"
                     /translation="LLRRLREAHGPLMFHQSGGCCDGSAPMCYLAGEFRTGASDILLGE
                     LAVDGVEEPVEFWMSRSQYEAWRHTRLIVDVVPGRGSGFSLEAPEGVRFLIRSRV"
     gene            complement(7546..8115)
                     /db_xref="GeneID:1096616"
                     /gene_synonym="SCG11A.24c"
                     /locus_tag="SCO1193"
     CDS             complement(7546..8115)
                     /codon_start=1
                     /db_xref="GeneID:1096616"
                     /gene_functions="regulatory (smcogs) SMCOG1224:TetR family
                     transcriptional regulator (Score: 131.6; E-value: 5.1e-40)"
                     /gene_kind="regulatory"
                     /gene_synonym="SCG11A.24c"
                     /locus_tag="SCO1193"
                     /note="SCG11A.24c, probable tetR-family transcriptional
                     regulator, len: 189 aa; similar to TR:CAB56380
                     (EMBL:AL118515) Streptomyces coelicolor probable
                     tetR-family transcriptional regulator SCD17.03, 226 aa;
                     fasta scores: opt: 233 z-score: 295.6 E(): 4.3e-09; 35.2%
                     identity in 176 aa overlap. Contains match to Pfam entry
                     PF00440 tetR, Bacterial regulatory proteins, tetR family"
                     /product="TetR family transcriptional regulator"
                     /protein_id="NP_625483.1"
                     /transl_table=11
                     /translation="MAQRRRGAALEKALLDAAWGELAERGYARFTMDGVVRRAGTSPPV
                     LYRRWAHRDELARAAVAHVLEEARVDTPDTGTLRGDLLALMREIGTANAQLVILMYAHL
                     AGYCQETGTSPGELLDAARGKSADALAEVYDRAVARGEARPERLTGRVRSLPFDLLRQE
                     ILATLAPVPEDVVEEIVDTIFLPLVS"
     PFAM_domain     complement(7567..7899)
                     /aSDomain="TetR_C_11"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF16859.8"
                     /description="Tetracyclin repressor-like, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1193_0189"
                     /evalue="4.80E-20"
                     /label="SCO1193"
                     /locus_tag="SCO1193"
                     /protein_end="183"
                     /protein_start="72"
                     /score="72.1"
                     /tool="antismash"
                     /translation="PDTGTLRGDLLALMREIGTANAQLVILMYAHLAGYCQETGTSPGE
                     LLDAARGKSADALAEVYDRAVARGEARPERLTGRVRSLPFDLLRQEILATLAPVPEDVV
                     EEIVDTI"
     PFAM_domain     complement(7936..8076)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00440.26"
                     /db_xref="GO:0003677"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1193_0188"
                     /evalue="7.00E-12"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /label="SCO1193"
                     /locus_tag="SCO1193"
                     /protein_end="60"
                     /protein_start="13"
                     /score="45.1"
                     /tool="antismash"
                     /translation="LLDAAWGELAERGYARFTMDGVVRRAGTSPPVLYRRWAHRDELAR
                     AA"
     misc_feature    complement(7972..8076)
                     /gene_synonym="SCG11A.24c"
                     /locus_tag="SCO1193"
                     /note="Pfam match to entry PF00440 tetR, Bacterial
                     regulatory proteins, tetR family, score 17.80, E-value
                     0.0034"
     regulatory      complement(8122..8126)
                     /regulatory_class="ribosome_binding_site"
     regulatory      8203..8207
                     /regulatory_class="ribosome_binding_site"
     gene            8217..9707
                     /db_xref="GeneID:1096617"
                     /gene_synonym="SCG11A.25"
                     /locus_tag="SCO1194"
     CDS             8217..9707
                     /codon_start=1
                     /db_xref="GeneID:1096617"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 283.3; E-value:
                     4.3e-86)"
                     /gene_kind="transport"
                     /gene_synonym="SCG11A.25"
                     /locus_tag="SCO1194"
                     /note="SCG11A.25, probable export protein, len: 496 aa;
                     similar to TR:P72184 (EMBL:U51164) Propionibacterium
                     freudenreichii membrane-bound transport protein HemX, 487
                     aa; fasta scores: opt: 1371 z-score: 1416.9 E(): 0; 47.0%
                     identity in 474 aa overlap and to SW:PUR8_STRLP
                     (EMBL:X76855) Streptomyces lipmanii (Streptomyces
                     alboniger) puromycin resistance protein Pur8, 503aa; fasta
                     scores: opt: 576 z-score: 598.4 E(): 5.9e-26; 30.2%
                     identity in 493 aa overlap"
                     /product="export protein"
                     /protein_id="NP_625484.1"
                     /transl_table=11
                     /translation="MSIPHGAASAAARPDRVDPAVRRIGATLVVGALGVVFDTTVVSVA
                     LDDLAKAFDAPLATVQWVSTGYLLAVFVTIPLAVWAQARFGGRRLWIAALGGFLLGSVL
                     SALAWNATSLIVFRVVQGLAGGIMMPLMATLLMQAARGSHPGRVMAIITVPTALGPILG
                     PVLGGLVLHLADWRWMFFVNIPFCVVGGWLALRNLPDDRPEPGGPRGRLDVVGLLLLCP
                     GVAALVYGLSRVEGGAGTTGAAVLVPLLGGLALVGGFTARSLTRPGGALIDLRLFRHRA
                     VASSAALLFLGGIALYGPMMLLPLYFQQVRGEDALGAGLALIPQGVGALLARALAGRYM
                     DRVGPRRVAVTAFALVAVATVPFAFVTAGTGGAVLMAALFVRGIALGAAMIAPMGAAYV
                     GLRHQEIPDAGVITRVAQQIGGSVGIALLAVVLQHAAAGAHGPSALAGAFDRAFWWSAV
                     LTALAVPLCLLLPGRPEPPPPARTTRTGEAVDPRRPTV"
     aSDomain        8295..9524
                     /aSDomain="TIGR00711"
                     /aSTool="tigrfam"
                     /description="efflux_EmrB: drug resistance MFS transporter,
                     drug:H+ antiporter-2 (14 Spanner) (DHA2) family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO1194_0016"
                     /evalue="2.60E-87"
                     /identifier="TIGR00711"
                     /label="SCO1194"
                     /locus_tag="SCO1194"
                     /protein_end="436"
                     /protein_start="26"
                     /score="291.5"
                     /tool="antismash"
                     /translation="TLVVGALGVVFDTTVVSVALDDLAKAFDAPLATVQWVSTGYLLAV
                     FVTIPLAVWAQARFGGRRLWIAALGGFLLGSVLSALAWNATSLIVFRVVQGLAGGIMMP
                     LMATLLMQAARGSHPGRVMAIITVPTALGPILGPVLGGLVLHLADWRWMFFVNIPFCVV
                     GGWLALRNLPDDRPEPGGPRGRLDVVGLLLLCPGVAALVYGLSRVEGGAGTTGAAVLVP
                     LLGGLALVGGFTARSLTRPGGALIDLRLFRHRAVASSAALLFLGGIALYGPMMLLPLYF
                     QQVRGEDALGAGLALIPQGVGALLARALAGRYMDRVGPRRVAVTAFALVAVATVPFAFV
                     TAGTGGAVLMAALFVRGIALGAAMIAPMGAAYVGLRHQEIPDAGVITRVAQQIGGSVGI
                     ALLAVVLQHAA"
     PFAM_domain     8304..9488
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07690.19"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1194_0190"
                     /evalue="4.00E-46"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO1194"
                     /locus_tag="SCO1194"
                     /protein_end="424"
                     /protein_start="29"
                     /score="157.7"
                     /tool="antismash"
                     /translation="VGALGVVFDTTVVSVALDDLAKAFDAPLATVQWVSTGYLLAVFVT
                     IPLAVWAQARFGGRRLWIAALGGFLLGSVLSALAWNATSLIVFRVVQGLAGGIMMPLMA
                     TLLMQAARGSHPGRVMAIITVPTALGPILGPVLGGLVLHLADWRWMFFVNIPFCVVGGW
                     LALRNLPDDRPEPGGPRGRLDVVGLLLLCPGVAALVYGLSRVEGGAGTTGAAVLVPLLG
                     GLALVGGFTARSLTRPGGALIDLRLFRHRAVASSAALLFLGGIALYGPMMLLPLYFQQV
                     RGEDALGAGLALIPQGVGALLARALAGRYMDRVGPRRVAVTAFALVAVATVPFAFVTAG
                     TGGAVLMAALFVRGIALGAAMIAPMGAAYVGLRHQEIPDAGVITRVAQQIGGSVG"
     gene            complement(9697..9891)
                     /db_xref="GeneID:1096618"
                     /gene_synonym="SCG11A.26c"
                     /locus_tag="SCO1195"
     CDS             complement(9697..9891)
                     /codon_start=1
                     /db_xref="GeneID:1096618"
                     /gene_synonym="SCG11A.26c"
                     /locus_tag="SCO1195"
                     /note="SCG11A.26c, membrane protein, len: 64 aa. Contains
                     possible hydrophobic membrane spanning regions"
                     /product="hypothetical protein"
                     /protein_id="NP_625485.1"
                     /transl_table=11
                     /translation="MAVSISVVLLLSILAVLFLRNGGLKVSHALVCLLLGFYLASTSIA
                     PTINSGLTATADIVGSLRP"
     regulatory      complement(9898..9902)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(10006..10869)
                     /db_xref="GeneID:1096619"
                     /gene_synonym="SCG11A.27c"
                     /locus_tag="SCO1196"
     CDS             complement(10006..10869)
                     /codon_start=1
                     /db_xref="GeneID:1096619"
                     /gene_synonym="SCG11A.27c"
                     /locus_tag="SCO1196"
                     /note="SCG11A.27c, hypothetical protein, len: 287 aa.
                     Contains possible N-terminal region signal peptide
                     sequence"
                     /product="hypothetical protein"
                     /protein_id="NP_625486.1"
                     /transl_table=11
                     /translation="MALTTRRRALTTLGAALTGAVALPAGTALASQGGHGPRPLWRAHA
                     HNDYEHPRPLLDALDHRFGSVEADIYLVGGQLLVAHDPEDLDPSRTLESLYLDPLAARV
                     RAHHGRVYRRDRGSLQLLIDIKTEGEATYLELDRRLRRYKNLFTSYAHGRVFPGAVTAV
                     VSGDRAARAPMAAQRSRRAFYDGRLTDLGTVAPASFVPLISDNWTLNFTWQGVGTFPAA
                     ERRRLRDIVGAAHARGQRVRFWATPDVAGPARDAVWAELLAAGVDHLNTDDLAGIEAFL
                     DAHRDA"
     PFAM_domain     complement(10045..10152)
                     /aSDomain="GDPD_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13653.9"
                     /description="Glycerophosphoryl diester phosphodiesterase
                     family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1196_0191"
                     /evalue="2.90E-12"
                     /label="SCO1196"
                     /locus_tag="SCO1196"
                     /protein_end="275"
                     /protein_start="239"
                     /score="46.7"
                     /tool="antismash"
                     /translation="RVRFWATPDVAGPARDAVWAELLAAGVDHLNTDDLA"
     regulatory      complement(10876..10880)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(11039..12127)
                     /db_xref="GeneID:1096620"
                     /gene_synonym="SCG11A.28c"
                     /locus_tag="SCO1197"
     CDS             complement(11039..12127)
                     /codon_start=1
                     /db_xref="GeneID:1096620"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 128.5; E-value:
                     5.4e-39)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCG11A.28c"
                     /locus_tag="SCO1197"
                     /note="SCG11A.28c, possible acyl-CoA dehydrogenase, len:362
                     aa; low similarity to TR:AAD44195 (EMBL:AF142581)
                     Streptomyces coelicolor acyl-CoA dehydrogenase AcdH, 386
                     aa; fasta scores: opt: 266 z-score: 294.1 E(): 5.2e-09;
                     28.3% identity in 392 aa overlap and to SW:ACDS_CLOAB
                     (EMBL:U17110) Clostridium acetobutylicum acyl-CoA
                     dehydrogenase, short-chain specific (EC 1.3.99.2) (ScaD)
                     (butyryl-CoA dehydrogenase) Bcd, 379 aa; fasta scores: opt:
                     231 z-score: 256.5 E(): 6.5e-07; 26.5% identity in 378 aa
                     overlap. Contains two matches to Pfam entry PF00441
                     Acyl-CoA_dh, Acyl-CoA dehydrogenase"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="NP_625487.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 9.2e-17, bitscore:
                     60.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.2e-25, bitscore:
                     89.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAQPEPALLLSEEEEALRAAVRDLLTDHCDPAGVITRTESAARH
                     DVSLWKALAGSMGLAGLLIPEELGGQGATHREAAVVLEELGRAVAPVPYLTSAVVATEA
                     LLACGADDLLGELASATTVAVLAVGLHVAPGGAAPRVRLEGGALHGELTGIADASVADV
                     LLVPADDGGLYAVAAADAAVTGQVSLDSTRPLARVTLDGAPGRRLGDAEPAVRRALRAG
                     AGLLAAEQLGLADWLLTETVRHLKERKQFNRQVGGFQALKHRLSRLWLEVAGLRAAARN
                     AADALATGADTDVAVAVAQAYAAQVAVHAAEEALQLHGGIGMTWEHPVHLYLKRAKADS
                     IAYGAPGTHRAALAELVDLRAP"
     PFAM_domain     complement(11063..11485)
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00441.27"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1197_0193"
                     /evalue="3.00E-25"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO1197"
                     /locus_tag="SCO1197"
                     /protein_end="355"
                     /protein_start="214"
                     /score="89.3"
                     /tool="antismash"
                     /translation="VRRALRAGAGLLAAEQLGLADWLLTETVRHLKERKQFNRQVGGFQ
                     ALKHRLSRLWLEVAGLRAAARNAADALATGADTDVAVAVAQAYAAQVAVHAAEEALQLH
                     GGIGMTWEHPVHLYLKRAKADSIAYGAPGTHRAALAE"
     misc_feature    complement(11141..11455)
                     /gene_synonym="SCG11A.28c"
                     /locus_tag="SCO1197"
                     /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA
                     dehydrogenase, score 49.70, E-value 9.5e-14"
     PFAM_domain     complement(11792..12094)
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02771.19"
                     /db_xref="GO:0016627"
                     /db_xref="GO:0050660"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1197_0192"
                     /evalue="1.00E-15"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /gene_ontologies="GO:0050660: flavin adenine dinucleotide
                     binding"
                     /label="SCO1197"
                     /locus_tag="SCO1197"
                     /protein_end="112"
                     /protein_start="11"
                     /score="58.5"
                     /tool="antismash"
                     /translation="SEEEEALRAAVRDLLTDHCDPAGVITRTESAARHDVSLWKALAGS
                     MGLAGLLIPEELGGQGATHREAAVVLEELGRAVAPVPYLTSAVVATEALLACGADD"
     misc_feature    complement(11834..12097)
                     /gene_synonym="SCG11A.28c"
                     /locus_tag="SCO1197"
                     /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA
                     dehydrogenase, score 53.10, E-value 9.4e-15"
     gene            complement(12124..13305)
                     /db_xref="GeneID:1096621"
                     /gene_synonym="SCG11A.29c"
                     /locus_tag="SCO1198"
     CDS             complement(12124..13305)
                     /codon_start=1
                     /db_xref="GeneID:1096621"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 223.6; E-value:
                     7e-68)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCG11A.29c"
                     /locus_tag="SCO1198"
                     /note="SCG11A.29c, probable acyl-CoA dehydrogenase, len:393
                     aa; similar to TR:Q54857 (EMBL:) Streptomyces purpurascens
                     acyl-CoA dehydrogenase FamB (fragment), 288 aa; fasta
                     scores: opt: 1195 z-score: 1377.5 E(): 0; 83.2% identity in
                     208 aa overlap and to SW:ACD_MYCLE (EMBL:U00012)
                     Mycobacterium leprae acyl-CoA dehydrogenase (EC 1.3.99.-)
                     Acd or B1308_F1_34, 389 aa; fasta scores: opt: 386 z-score:
                     447.1 E(): 1.6e-17; 28.5% identity in 376 aa overlap.
                     Contains two matches to Pfam entry PF00441 Acyl-CoA_dh,
                     Acyl-CoA dehydrogenase"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="NP_625488.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.2e-12, bitscore:
                     47.4, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.4e-20, bitscore:
                     72.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.6e-19, bitscore:
                     68.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDAAELRDRTRELLAAHPPADTDRLDFLRARFDAGLAWVHYPQG
                     LGGLGAPRALQAVVDAELAAAGAPDNDPRRIGIGLGMAAPTILQYGTEEQKRRLLRPLW
                     TGEEVWCQLFSEPGAGSDLAALGTRAVRDGEDWVVNGQKVWTSSAHLARWAILIARTDP
                     DVPKHQGITYFVCDMTDPGVEVRPLRQITGEAEFNEVFLTDVRIPDSRRLGEVGDGWRV
                     AQTTLNNERVAIGGTPIPREGGMIGKIAETWRERPELRTHDLHQRLLGLWVEAEVARLT
                     GVRLRQQLAAGQPGPEGAGMKLNFARLNQEISGLEVELLGAEGLLYDDWTMRRPELVDF
                     TGRDAGYRYLRSKGNSIEGGTSEVLLNIVAERVLGLPAEPRTDKDVAWKDLAR"
     PFAM_domain     complement(12184..12657)
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00441.27"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1198_0196"
                     /evalue="6.50E-19"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO1198"
                     /locus_tag="SCO1198"
                     /protein_end="374"
                     /protein_start="216"
                     /score="68.8"
                     /tool="antismash"
                     /translation="GDGWRVAQTTLNNERVAIGGTPIPREGGMIGKIAETWRERPELRT
                     HDLHQRLLGLWVEAEVARLTGVRLRQQLAAGQPGPEGAGMKLNFARLNQEISGLEVELL
                     GAEGLLYDDWTMRRPELVDFTGRDAGYRYLRSKGNSIEGGTSEVLLNIVAERVL"
     misc_feature    complement(12199..12255)
                     /gene_synonym="SCG11A.29c"
                     /locus_tag="SCO1198"
                     /note="PS00095 C-5 cytosine-specific DNA methylases
                     C-terminal signature"
     misc_feature    complement(12589..12696)
                     /gene_synonym="SCG11A.29c"
                     /locus_tag="SCO1198"
                     /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA
                     dehydrogenase, score 14.30, E-value 0.0022"
     PFAM_domain     complement(12694..12975)
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02770.22"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1198_0195"
                     /evalue="1.20E-20"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO1198"
                     /locus_tag="SCO1198"
                     /protein_end="204"
                     /protein_start="110"
                     /score="73.6"
                     /tool="antismash"
                     /translation="CQLFSEPGAGSDLAALGTRAVRDGEDWVVNGQKVWTSSAHLARWA
                     ILIARTDPDVPKHQGITYFVCDMTDPGVEVRPLRQITGEAEFNEVFLTD"
     misc_feature    complement(12751..13050)
                     /gene_synonym="SCG11A.29c"
                     /locus_tag="SCO1198"
                     /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA
                     dehydrogenase, score 106.30, E-value 2.3e-30"
     PFAM_domain     complement(12985..13293)
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02771.19"
                     /db_xref="GO:0016627"
                     /db_xref="GO:0050660"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1198_0194"
                     /evalue="4.20E-12"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /gene_ontologies="GO:0050660: flavin adenine dinucleotide
                     binding"
                     /label="SCO1198"
                     /locus_tag="SCO1198"
                     /protein_end="107"
                     /protein_start="4"
                     /score="46.8"
                     /tool="antismash"
                     /translation="AELRDRTRELLAAHPPADTDRLDFLRARFDAGLAWVHYPQGLGGL
                     GAPRALQAVVDAELAAAGAPDNDPRRIGIGLGMAAPTILQYGTEEQKRRLLRPLWTGE"
     gene            complement(13302..14282)
                     /db_xref="GeneID:1096622"
                     /gene_synonym="SCG11A.30c"
                     /locus_tag="SCO1199"
     CDS             complement(13302..14282)
                     /NRPS_PKS="Domain: PKS_ER (19-313). E-value: 1e-50. Score:
                     164.5. Matches aSDomain: nrpspksdomains_SCO1199_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:1096622"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 274.6; E-value: 1.8e-83)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCG11A.30c"
                     /locus_tag="SCO1199"
                     /note="SCG11A.30c, probable oxidoreductase, len: 326 aa;
                     highly similar to TR:Q54856 (EMBL:X61931) Streptomyces
                     purpurascens famA (FAS domain), 230 aa; fasta scores: opt:
                     1015 z-score: 1089.1 E(): 0; 79.5% identity in 239 aa
                     overlap and to SW:QOR_PSEAE (EMBL:X85015) Pseudomonas
                     aeruginosa quinone oxidoreductase (EC 1.6.5.5)
                     (NADH:quinone reductase) Qor, 325 aa; fasta scores: opt:
                     446 z-score: 482.5 E(): 1.7e-19; 34.1% identity in 323 aa
                     overlap. Contains match to Pfam entry PF00107 adh_zinc,
                     Zinc-binding dehydrogenases and match to Prosite entry
                     PS01162 Quinone oxidoreductase / zeta-crystallin signature"
                     /product="oxidoreductase"
                     /protein_id="NP_625489.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 7.7e-29, bitscore:
                     99.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAWQVHENGEPGEVMRLADVAPPTPGEGQVLLRVRAANINFPDA
                     LMCRGQYQVRPPLPFTPGVEICGETEEGRRVIANPALPHGGFAEYALADARALLPAPDS
                     LDDAEAAALHIGYQTGWFGLHRRARLEAGETLLVHAAAGGVGSAAVQLGKAAGATVIGV
                     VGGSQKAAVARELGCDVVVDRHAEDVVAAVKEATGGRGADVIYDPVGGQAYAQSAKVVA
                     FEGRIVVVGFASGTIPSPALNHALVKNYAILGLHWGLYNTKDPKLVRHCHEQLTELAAR
                     GAIKPLVSERVPLADAADAVQRVADGRTTGRLAVVPENLDKGAAA"
     regulatory      complement(13313..13316)
                     /gene_synonym="SCG11A.30c"
                     /locus_tag="SCO1199"
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(13335..14243)
                     /gene_synonym="SCG11A.30c"
                     /locus_tag="SCO1199"
                     /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases, score 36.80, E-value 1e-11"
     aSDomain        complement(13344..14225)
                     /ASF="ER domain putatively catalyzing 2S-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO1199_PKS_ER.1"
                     /evalue="1.00E-50"
                     /label="SCO1199_PKS_ER.1"
                     /locus_tag="SCO1199"
                     /protein_end="313"
                     /protein_start="19"
                     /score="164.5"
                     /tool="antismash"
                     /translation="DVAPPTPGEGQVLLRVRAANINFPDALMCRGQYQVRPPLPFTPGV
                     EICGETEEGRRVIANPALPHGGFAEYALADARALLPAPDSLDDAEAAALHIGYQTGWFG
                     LHRRARLEAGETLLVHAAAGGVGSAAVQLGKAAGATVIGVVGGSQKAAVARELGCDVVV
                     DRHAEDVVAAVKEATGGRGADVIYDPVGGQAYAQSAKVVAFEGRIVVVGFASGTIPSPA
                     LNHALVKNYAILGLHWGLYNTKDPKLVRHCHEQLTELAARGAIKPLVSERVPLADAADA
                     VQRVADGRTTGRL"
     PFAM_domain     complement(13494..13853)
                     /aSDomain="ADH_zinc_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00107.29"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1199_0197"
                     /evalue="1.90E-28"
                     /label="SCO1199"
                     /locus_tag="SCO1199"
                     /protein_end="263"
                     /protein_start="143"
                     /score="99.2"
                     /tool="antismash"
                     /translation="GVGSAAVQLGKAAGATVIGVVGGSQKAAVARELGCDVVVDRHAED
                     VVAAVKEATGGRGADVIYDPVGGQAYAQSAKVVAFEGRIVVVGFASGTIPSPALNHALV
                     KNYAILGLHWGLYNTK"
     misc_feature    complement(13821..13886)
                     /gene_synonym="SCG11A.30c"
                     /locus_tag="SCO1199"
                     /note="PS01162 Quinone oxidoreductase / zeta-crystallin
                     signature"
     CDS_motif       complement(13827..13886)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCO1199_0001"
                     /evalue="7.10E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="SCO1199"
                     /protein_end="152"
                     /protein_start="132"
                     /score="24.8"
                     /tool="antismash"
                     /translation="GETLLVHAAAGGVGSAAVQL"
     regulatory      complement(14289..14293)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(14367..14942)
                     /db_xref="GeneID:1096623"
                     /gene_synonym="SCG11A.31c"
                     /locus_tag="SCO1200"
     CDS             complement(14367..14942)
                     /codon_start=1
                     /db_xref="GeneID:1096623"
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 148.8; E-value: 3.1e-45)"
                     /gene_kind="other"
                     /gene_synonym="SCG11A.31c"
                     /locus_tag="SCO1200"
                     /note="SCG11A.31c, probable regulatory protein, len 191 aa;
                     similar to TR:Q54855 (EMBL:X61931) Streptomyces
                     purpurascens ORF1, 90 aa; fasta scores: opt: 560 z-score:
                     686.7 E(): 7.2e-31; 85.6% identity in 90 aa overlap and to
                     TR:CAB39703 (EMBL:AL049485) Streptomyces coelicolor
                     DNA-binding protein SC6A5.19, 204 aa; fasta scores: opt:
                     382 z-score: 468.0 E(): 1.1e-18; 39.2% identity in 176 aa
                     overlap and to Streptomyces coelicolor SC6G4.21, fasta
                     scores: opt: 717 z-score: 721.2 E(): 8e-35; 60.0% identity
                     in 190 aa overlap. Contains match to Pfam entry PF01381
                     HTH_3, Helix-turn-helix and a predicted possible motif at
                     residues 25..46 (+6.09 SD)"
                     /product="regulatory protein"
                     /protein_id="NP_625490.1"
                     /transl_table=11
                     /translation="MTTPDDVLAGVGPRLRQVRKEREVTLAALSEATGISVSTLSRLES
                     GLRRPSLELLLPIARAHQVPLDELVGAPPVGDPRVRARPVVRHGRTHWPLTRQAGGLQA
                     FKVLEPQSREEPDPRTHEGYEWLYVLSGRLRLVLGEHDVVLSAGEAAEFDTRVPHWFGS
                     TGEGPAEFLSLFGPQGERMHVRARPAQA"
     PFAM_domain     complement(14418..14624)
                     /aSDomain="Cupin_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07883.14"
                     /description="Cupin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1200_0199"
                     /evalue="1.40E-16"
                     /label="SCO1200"
                     /locus_tag="SCO1200"
                     /protein_end="175"
                     /protein_start="106"
                     /score="60.0"
                     /tool="antismash"
                     /translation="VLEPQSREEPDPRTHEGYEWLYVLSGRLRLVLGEHDVVLSAGEAA
                     EFDTRVPHWFGSTGEGPAEFLSLF"
     misc_feature    complement(14736..14900)
                     /gene_synonym="SCG11A.31c"
                     /locus_tag="SCO1200"
                     /note="Pfam match to entry PF01381 HTH_3, Helix-turn-helix,
                     score 59.00, E-value 9.9e-14"
     PFAM_domain     complement(14736..14900)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01381.25"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1200_0198"
                     /evalue="1.40E-14"
                     /label="SCO1200"
                     /locus_tag="SCO1200"
                     /protein_end="69"
                     /protein_start="14"
                     /score="54.0"
                     /tool="antismash"
                     /translation="LRQVRKEREVTLAALSEATGISVSTLSRLESGLRRPSLELLLPIA
                     RAHQVPLDEL"
     regulatory      15007..15011
                     /regulatory_class="ribosome_binding_site"
     gene            15020..15985
                     /db_xref="GeneID:1096624"
                     /gene_synonym="2SCG58.01; SCG11A.32"
                     /locus_tag="SCO1201"
     CDS             15020..15985
                     /codon_start=1
                     /db_xref="GeneID:1096624"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176:alkyl hydroperoxide reductase subunit (Score:
                     333.9; E-value: 2.7e-101)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="2SCG58.01; SCG11A.32"
                     /locus_tag="SCO1201"
                     /note="2SCG58.01, possible reductase (fragment), len: >43
                     aa; C-terminal part of TR:Q9RJW9 (EMBL:AL133210)
                     Streptomyces coelicolor reductase (fragment) SCF37.32, 311
                     aa; SCG11A.32, possible reductase, len: >310 aa; similar to
                     TR:Q9Z9W3 (EMBL:AB011836) Bacillus sp. (strain C-125) alkyl
                     hydroperoxide reductase large subunit (EC 1.6.99.3) AhpF,
                     305 aa; fasta scores: opt: 668 z-score: 747.2 E(): 0; 37.3%
                     identity in 295 aa overlap and to SW:AHPF_PSEPU
                     (EMBL:AB010689) Pseudomonas putida alkyl hydroperoxide
                     reductase subunit F (EC 1.6.4.-) AhpF, 520 aa; fasta
                     scores: opt: 338 z-score: 378.9 E(): 9.9e-14; 28.6%
                     identity in 308 aa overlap"
                     /product="reductase"
                     /protein_id="NP_733526.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.7e-22, bitscore:
                     77.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQNTNLKDPKDPSGRYDVVVVGGGAAGLSAALVLGRSRLRTLVV
                     DAGEPRNAPSDHMQGYLTRDGMSPAEFLALGREEIARYGVDLVRDRAVDVSSDGDFAVE
                     LGGGDTVHARRLIVTTGLRDELPAVPGVAERYGRDVLHCPFCHGWEVRDERFGVLASSP
                     LSVHQALMVSGWSDDVTLFLHTVAERELSDDDLRRLAAAGVKVVPGEVAALRVEDDRLT
                     GVRLADGTAHDRTVVFVAPKAVPQTGLMERLGAELQETPFGAYPVVDPTGRTSVPGVWT
                     AGNAMGFAEQVVHAASGGYRAASAVVGDLIMSALDAALAE"
     PFAM_domain     15068..15913
                     /aSDomain="Pyr_redox_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07992.17"
                     /db_xref="GO:0016491"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1201_0200"
                     /evalue="1.20E-21"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO1201"
                     /locus_tag="SCO1201"
                     /protein_end="298"
                     /protein_start="16"
                     /score="77.4"
                     /tool="antismash"
                     /translation="YDVVVVGGGAAGLSAALVLGRSRLRTLVVDAGEPRNAPSDHMQGY
                     LTRDGMSPAEFLALGREEIARYGVDLVRDRAVDVSSDGDFAVELGGGDTVHARRLIVTT
                     GLRDELPAVPGVAERYGRDVLHCPFCHGWEVRDERFGVLASSPLSVHQALMVSGWSDDV
                     TLFLHTVAERELSDDDLRRLAAAGVKVVPGEVAALRVEDDRLTGVRLADGTAHDRTVVF
                     VAPKAVPQTGLMERLGAELQETPFGAYPVVDPTGRTSVPGVWTAGNAMGFAEQVVHAAS
                     G"
     gene            16076..17614
                     /db_xref="GeneID:1096625"
                     /gene="ligB"
                     /gene_synonym="2SCG58.02"
                     /locus_tag="SCO1202"
     CDS             16076..17614
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /db_xref="GeneID:1096625"
                     /gene="ligB"
                     /gene_synonym="2SCG58.02"
                     /locus_tag="SCO1202"
                     /note="catalyzes the ATP-dependent formation of a
                     phosphodiester at the site of a single-strand break in
                     duplex DNA"
                     /product="ATP-dependent DNA ligase"
                     /protein_id="NP_625491.1"
                     /transl_table=11
                     /translation="MLLARLAQVSREVAATSARSRKTVLLAELFREAEAADVPVVIPYL
                     AGRLPQGRIGVGWKVLSRRVPPADAPTLTVRDVDARLTRLGAVSGAGSQAERTRLVGEL
                     MGAATEDEQRFLIGLLTGEVRQGALDAAAVEGLAAATDAPPADVRRAVMLAGSLQTVAE
                     ALLADGPGALDRFRLTVGQPVLPMLAHSASSVAEAVGKLGAAAVEEKLDGIRVQVHRDG
                     GTVRIYTRTLDDITDRLPEVTEAALALPGERFILDGEAISLDADGRPRSFQETAGRVGS
                     RTDVATAARAVPVSAVFFDVLSVDGRDLLDLPLTERHAELARLVPEPLRVRRTLVHGPE
                     DTGAAEEFLARTLARGHEGVVVKGLDAAYSAGRRGASWLKVKPVHTLDLVVLAAEWGHG
                     RRTGKLSNLHLGARTADGSFAMLGKTFKGMTDALLTWQTERLKELAVEEHGWGVTVRPE
                     LVVEIAYDGLQRSTRYPAGVTLRFARVVRYREDKRPEDADTVDTLLAAHPGVAP"
     PFAM_domain     16250..16465
                     /aSDomain="DNA_ligase_A_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04675.17"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0003910"
                     /db_xref="GO:0006281"
                     /db_xref="GO:0006310"
                     /description="DNA ligase N terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1202_0201"
                     /evalue="5.10E-08"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0003910: DNA ligase (ATP) activity"
                     /gene_ontologies="GO:0006281: DNA repair"
                     /gene_ontologies="GO:0006310: DNA recombination"
                     /label="SCO1202"
                     /locus_tag="SCO1202"
                     /protein_end="130"
                     /protein_start="58"
                     /score="33.5"
                     /tool="antismash"
                     /translation="KVLSRRVPPADAPTLTVRDVDARLTRLGAVSGAGSQAERTRLVGE
                     LMGAATEDEQRFLIGLLTGEVRQGALD"
     aSDomain        16283..17581
                     /aSDomain="TIGR00574"
                     /aSTool="tigrfam"
                     /description="dnl1: DNA ligase I, ATP-dependent (dnl1)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO1202_0017"
                     /evalue="4.00E-83"
                     /identifier="TIGR00574"
                     /label="SCO1202"
                     /locus_tag="SCO1202"
                     /protein_end="502"
                     /protein_start="69"
                     /score="277.8"
                     /tool="antismash"
                     /translation="APTLTVRDVDARLTRLGAVSGAGSQAERTRLVGELMGAATEDEQR
                     FLIGLLTGEVRQGALDAAAVEGLAAATDAPPADVRRAVMLAGSLQTVAEALLADGPGAL
                     DRFRLTVGQPVLPMLAHSASSVAEAVGKLGAAAVEEKLDGIRVQVHRDGGTVRIYTRTL
                     DDITDRLPEVTEAALALPGERFILDGEAISLDADGRPRSFQETAGRVGSRTDVATAARA
                     VPVSAVFFDVLSVDGRDLLDLPLTERHAELARLVPEPLRVRRTLVHGPEDTGAAEEFLA
                     RTLARGHEGVVVKGLDAAYSAGRRGASWLKVKPVHTLDLVVLAAEWGHGRRTGKLSNLH
                     LGARTADGSFAMLGKTFKGMTDALLTWQTERLKELAVEEHGWGVTVRPELVVEIAYDGL
                     QRSTRYPAGVTLRFARVVRYREDKRPEDADTVDT"
     misc_feature    16622..17542
                     /gene="ligB"
                     /gene_synonym="2SCG58.02"
                     /locus_tag="SCO1202"
                     /note="Pfam match to entry PF01068 DNA_ligase, DNA ligase,
                     score 354.70, E-value 1e-102"
     PFAM_domain     16631..17221
                     /aSDomain="DNA_ligase_A_M"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01068.24"
                     /db_xref="GO:0003910"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0006281"
                     /db_xref="GO:0006310"
                     /description="ATP dependent DNA ligase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1202_0202"
                     /evalue="6.20E-45"
                     /gene_ontologies="GO:0003910: DNA ligase (ATP) activity"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0006281: DNA repair"
                     /gene_ontologies="GO:0006310: DNA recombination"
                     /label="SCO1202"
                     /locus_tag="SCO1202"
                     /protein_end="382"
                     /protein_start="185"
                     /score="153.5"
                     /tool="antismash"
                     /translation="PMLAHSASSVAEAVGKLGAAAVEEKLDGIRVQVHRDGGTVRIYTR
                     TLDDITDRLPEVTEAALALPGERFILDGEAISLDADGRPRSFQETAGRVGSRTDVATAA
                     RAVPVSAVFFDVLSVDGRDLLDLPLTERHAELARLVPEPLRVRRTLVHGPEDTGAAEEF
                     LARTLARGHEGVVVKGLDAAYSAGRRGASWLKVK"
     misc_feature    16697..16723
                     /gene="ligB"
                     /gene_synonym="2SCG58.02"
                     /locus_tag="SCO1202"
                     /note="PS00697 ATP-dependent DNA ligase AMP-binding site"
     PFAM_domain     17276..17551
                     /aSDomain="DNA_ligase_A_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04679.18"
                     /db_xref="GO:0003910"
                     /db_xref="GO:0006281"
                     /db_xref="GO:0006310"
                     /description="ATP dependent DNA ligase C terminal region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1202_0203"
                     /evalue="2.50E-15"
                     /gene_ontologies="GO:0003910: DNA ligase (ATP) activity"
                     /gene_ontologies="GO:0006281: DNA repair"
                     /gene_ontologies="GO:0006310: DNA recombination"
                     /label="SCO1202"
                     /locus_tag="SCO1202"
                     /protein_end="492"
                     /protein_start="400"
                     /score="57.0"
                     /tool="antismash"
                     /translation="RTGKLSNLHLGARTADGSFAMLGKTFKGMTDALLTWQTERLKELA
                     VEEHGWGVTVRPELVVEIAYDGLQRSTRYPAGVTLRFARVVRYREDK"
     gene            17611..18072
                     /db_xref="GeneID:1096626"
                     /gene_synonym="2SCG58.03"
                     /locus_tag="SCO1203"
     CDS             17611..18072
                     /codon_start=1
                     /db_xref="GeneID:1096626"
                     /gene_synonym="2SCG58.03"
                     /locus_tag="SCO1203"
                     /note="2SCG58.03, possible MutT-like protein, len: 153 aa;
                     similar to TR:CAB88476 (EMBL:AL353816) Streptomyces
                     coelicolor MutT-like protein SCD84.10c, 142 aa; fasta
                     scores: opt: 135 z-score: 171.1 E(): 0.046; 33.3% identity
                     in 129 aa overlap. Contains match to Prosite entry PS00893
                     mutT domain signature"
                     /product="MutT-like protein"
                     /protein_id="NP_625492.1"
                     /transl_table=11
                     /translation="MRRSAGLLLHRRAPGGGLQVLLGHMGGPFYSRRDAGAWTVPKGEY
                     DSGEPAWEAARREFEEELGLPPPEGEAVPLGEVRQAGGKLVTVWAVAADLDPATVVPGT
                     FRMEWPPRSGRTEEFPELDRVAWFGLDRAREVIVKAQAAFLDRLAEHSH"
     PFAM_domain     17656..18051
                     /aSDomain="NUDIX"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00293.31"
                     /description="NUDIX domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1203_0204"
                     /evalue="8.10E-12"
                     /label="SCO1203"
                     /locus_tag="SCO1203"
                     /protein_end="147"
                     /protein_start="15"
                     /score="45.4"
                     /tool="antismash"
                     /translation="GGLQVLLGHMGGPFYSRRDAGAWTVPKGEYDSGEPAWEAARREFE
                     EELGLPPPEGEAVPLGEVRQAGGKLVTVWAVAADLDPATVVPGTFRMEWPPRSGRTEEF
                     PELDRVAWFGLDRAREVIVKAQAAFLDR"
     misc_feature    17737..17796
                     /gene_synonym="2SCG58.03"
                     /locus_tag="SCO1203"
                     /note="PS00893 mutT domain signature"
     regulatory      18195..18200
                     /regulatory_class="ribosome_binding_site"
     misc_feature    18206..19588
                     /gene="gabD1"
                     /gene_synonym="2SCG58.04"
                     /locus_tag="SCO1204"
                     /note="Pfam match to entry PF00171 aldedh, Aldehyde
                     dehydrogenase family, score 437.70, E-value 9.9e-128"
     gene            18206..19591
                     /db_xref="GeneID:1096627"
                     /gene="gabD1"
                     /gene_synonym="2SCG58.04"
                     /locus_tag="SCO1204"
     CDS             18206..19591
                     /codon_start=1
                     /db_xref="GeneID:1096627"
                     /gene="gabD1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 476; E-value:
                     1.7e-144)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="2SCG58.04"
                     /locus_tag="SCO1204"
                     /note="NADP-dependent semialdehyde dehydrogenase; part of
                     alternative pathway from alpha-ketoglutarate to succinate"
                     /product="succinic semialdehyde dehydrogenase"
                     /protein_id="NP_625493.1"
                     /sec_met_domain="Aldedh (E-value: 1.7e-140, bitscore:
                     467.5, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIATVNPANGETLRTYEAMGEEEIERRIELAEATFRTYRTTGFY
                     ERAGLMRRAADLLEADQKEIGKVITTEMGKPVKQARAEAAKCAKAMRWYADHAAELLAD
                     EEPAEADVKDSGASRALVRYRPLGPVLAVMPWNFPLWQVIRFAAPALMAGNVGLLKHAS
                     NVPQTALYLEDLFHRAGFPEGCFQTLLIGSAQVDDVLRDERVRAATLTGSEPAGRAVAA
                     TAGEMIKKTVLELGGSDPFVVMPSADVERAAEVAVTARTQNAGQSCIAAKRFIVHTDVY
                     DAFAQRFTEGMRALKVGDPMDEETEVGPLSSEQGLNDLVELVDDAVRGGASVLCGGERP
                     DGPGWYYPPTVLAGVTRELRIHREEAFGPVATLYRAADLDEAVLIANDTDFGLSSNVWT
                     RDDADVDRFVRDLEAGGVYVNGMTASHPAFPFGGVKRSGYGRELSGHGIREFCNITTVW
                     HGA"
     PFAM_domain     18212..19576
                     /aSDomain="Aldedh"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00171.25"
                     /db_xref="GO:0016491"
                     /description="Aldehyde dehydrogenase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1204_0205"
                     /evalue="4.20E-140"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO1204"
                     /locus_tag="SCO1204"
                     /protein_end="457"
                     /protein_start="2"
                     /score="467.5"
                     /tool="antismash"
                     /translation="IATVNPANGETLRTYEAMGEEEIERRIELAEATFRTYRTTGFYER
                     AGLMRRAADLLEADQKEIGKVITTEMGKPVKQARAEAAKCAKAMRWYADHAAELLADEE
                     PAEADVKDSGASRALVRYRPLGPVLAVMPWNFPLWQVIRFAAPALMAGNVGLLKHASNV
                     PQTALYLEDLFHRAGFPEGCFQTLLIGSAQVDDVLRDERVRAATLTGSEPAGRAVAATA
                     GEMIKKTVLELGGSDPFVVMPSADVERAAEVAVTARTQNAGQSCIAAKRFIVHTDVYDA
                     FAQRFTEGMRALKVGDPMDEETEVGPLSSEQGLNDLVELVDDAVRGGASVLCGGERPDG
                     PGWYYPPTVLAGVTRELRIHREEAFGPVATLYRAADLDEAVLIANDTDFGLSSNVWTRD
                     DADVDRFVRDLEAGGVYVNGMTASHPAFPFGGVKRSGYGRELSGHGIREFCNITTV"
     gene            19629..19853
                     /db_xref="GeneID:1096628"
                     /gene_synonym="2SCG58.05"
                     /locus_tag="SCO1205"
     CDS             19629..19853
                     /codon_start=1
                     /db_xref="GeneID:1096628"
                     /gene_synonym="2SCG58.05"
                     /locus_tag="SCO1205"
                     /note="2SCG58.05, unknown, len: 74 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_625494.1"
                     /transl_table=11
                     /translation="MTLPLIVDDRGTLQVAASDVSKLLRTVGGRWLRLVETGEESLDED
                     TVAALTIELAKLADRIDVACIAHSSGPSS"
     PFAM_domain     19644..19841
                     /aSDomain="DUF6213"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19719.2"
                     /description="Family of unknown function (DUF6213)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1205_0206"
                     /evalue="6.90E-41"
                     /label="SCO1205"
                     /locus_tag="SCO1205"
                     /protein_end="71"
                     /protein_start="5"
                     /score="138.3"
                     /tool="antismash"
                     /translation="IVDDRGTLQVAASDVSKLLRTVGGRWLRLVETGEESLDEDTVAAL
                     TIELAKLADRIDVACIAHSSG"
     gene            20001..21125
                     /db_xref="GeneID:1096629"
                     /gene_synonym="2SCG58.06"
                     /locus_tag="SCO1206"
     CDS             20001..21125
                     /codon_start=1
                     /db_xref="GeneID:1096629"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:chalcone and stilbene synthase domain protein
                     (Score: 387.2; E-value: 9.4e-118)"
                     /gene_kind="biosynthetic"
                     /gene_synonym="2SCG58.06"
                     /locus_tag="SCO1206"
                     /note="2SCG58.06, possible polyketide synthase, len: 374
                     aa; highly similar to TR:Q54240 (EMBL:AB018074)
                     Streptomyces griseus ORF-1 protein similar to chalcone
                     synthase, 372 aa; fasta scores: opt: 1769 z-score: 1998.4
                     E(): 0; 70.4% identity in 361 aa overlap and to
                     SW:CHSJ_PETHY (EMBL:X14597) Petunia hybrida chalcone
                     synthase J (EC 2.3.1.74) ChsJ, 389 aa; fasta scores: opt:
                     412 z-score: 469.3 E(): 1.1e-18; 29.5% identity in 312 aa
                     overlap. Contains Pfam match to entry PF00195
                     Chal_stil_synt, Chalcone and stilbene synthases"
                     /product="1,3,6,8-tetrahydroxynaphthalene synthase"
                     /protein_id="NP_625495.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 1.2e-15,
                     bitscore: 56.5, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 7.5e-20,
                     bitscore: 70.4, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATLCRPSVSVPEHVITMEETLELARRRHTDHPQLPLALRLIENT
                     GVRTRHIVQPIEDTLEHPGFEDRNKVYEREAKSRVPAVIQRALDDAELLATDIDVIIYV
                     SCTGFMMPSLTAWLINEMGFDSTTRQIPIAQLGCAAGGAAINRAHDFCTAYPEANALIV
                     ACEFCSLCYQPTDLGVGSLLCNGLFGDGIAAAVVRGRGGTGVRLERNGSYLIPKTEDWI
                     MYDVKATGFHFLLDKRVPATMEPLAPALKELAGEHGWDASDLDFYIVHAGGPRILDDLS
                     TFLEVDPHAFRFSRATLTEYGNIASAVVLDALRRLFDEGGVEEGARGLLAGFGPGITAE
                     MSLGCWQTADVRRGIRQDVTRTAARGVSRRVRQA"
     PFAM_domain     20025..20591
                     /aSDomain="Chal_sti_synt_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00195.22"
                     /description="Chalcone and stilbene synthases, N-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1206_0207"
                     /evalue="5.10E-15"
                     /label="SCO1206"
                     /locus_tag="SCO1206"
                     /protein_end="197"
                     /protein_start="8"
                     /score="55.6"
                     /tool="antismash"
                     /translation="VSVPEHVITMEETLELARRRHTDHPQLPLALRLIENTGVRTRHIV
                     QPIEDTLEHPGFEDRNKVYEREAKSRVPAVIQRALDDAELLATDIDVIIYVSCTGFMMP
                     SLTAWLINEMGFDSTTRQIPIAQLGCAAGGAAINRAHDFCTAYPEANALIVACEFCSLC
                     YQPTDLGVGSLLCNGLFGDGIAAAVV"
     misc_feature    20118..21020
                     /gene_synonym="2SCG58.06"
                     /locus_tag="SCO1206"
                     /note="Pfam match to entry PF00195 Chal_stil_synt, Chalcone
                     and stilbene synthases, score 117.50, E-value 1.4e-33"
     PFAM_domain     20637..21023
                     /aSDomain="Chal_sti_synt_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02797.18"
                     /description="Chalcone and stilbene synthases, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1206_0208"
                     /evalue="3.90E-19"
                     /label="SCO1206"
                     /locus_tag="SCO1206"
                     /protein_end="341"
                     /protein_start="212"
                     /score="69.2"
                     /tool="antismash"
                     /translation="YLIPKTEDWIMYDVKATGFHFLLDKRVPATMEPLAPALKELAGEH
                     GWDASDLDFYIVHAGGPRILDDLSTFLEVDPHAFRFSRATLTEYGNIASAVVLDALRRL
                     FDEGGVEEGARGLLAGFGPGITAEM"
     regulatory      21113..21116
                     /gene_synonym="2SCG58.06"
                     /locus_tag="SCO1206"
                     /regulatory_class="ribosome_binding_site"
     gene            21122..22336
                     /db_xref="GeneID:1096630"
                     /gene_synonym="2SCG58.07"
                     /locus_tag="SCO1207"
     CDS             21122..22336
                     /codon_start=1
                     /db_xref="GeneID:1096630"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 379.8; E-value:
                     2.4e-115)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="2SCG58.07"
                     /locus_tag="SCO1207"
                     /note="2SCG58.07, probable cytochrome P450, len: 404 aa;
                     similar to SW:CPXF_STRGO (EMBL:M32239) Streptomyces
                     griseolus cytochrome P450-Su2 (EC 1.14.-.-) SubC, 402 aa;
                     fasta scores: opt: 791 z-score: 895.3 E(): 0; 37.1%
                     identity in 412 aa overlap and to TR:CAB88975
                     (EMBL:AL353864) Streptomyces coelicolor cytochrome P450
                     SC8F11.24c, 407 aa; fasta scores: opt: 1736 z-score: 1959.5
                     E(): 0; 61.2% identity in 407 aa overlap. Contains Pfam
                     match to entry PF00067 p450, Cytochrome P450 and match to
                     Prosite entry PS00086 Cytochrome P450 cysteine heme-iron
                     ligand signature"
                     /product="cytochrome P450"
                     /protein_id="NP_625496.1"
                     /sec_met_domain="p450 (E-value: 6.9e-18, bitscore: 63.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEETISQAVPPVRDWPAVDLPGSDFDPVLTELMREGPVTRISLP
                     NGEGWAWLVTRHDDVRLVTNDPRFGREAVMDRQVTRLAPHFIPARGAVGFLDPPDHTRL
                     RRSVAAAFTARGVERVRERSRGMLDELVDAMLRAGPPADLTEAVLSPFPIAVICELMGV
                     PATDRHSMHTWTQLILSSSHGAEVSERAKNEMNAYFSDLIGLRSDSAGEDVTSLLGAAV
                     GRDEITLSEAVGLAVLLQIGGEAVTNNSGQMFHLLLSRPELAERLRSEPEIRPRAIDEL
                     LRWIPHRNAVGLSRIALEDVEIKGVRIRAGDAVYVSYLAANRDPEVFPDPDRIDFERSP
                     NPHVSFGFGPHYCPGGMLARLESELLVDAVLDRVPGLKLAVAPEDVPFKKGALIRGPEA
                     LPVTW"
     misc_feature    21404..22288
                     /gene_synonym="2SCG58.07"
                     /locus_tag="SCO1207"
                     /note="Pfam match to entry PF00067 p450, Cytochrome P450,
                     score 144.70, E-value 4e-40"
     PFAM_domain     21950..22237
                     /aSDomain="p450"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00067.25"
                     /db_xref="GO:0004497"
                     /db_xref="GO:0005506"
                     /db_xref="GO:0016705"
                     /db_xref="GO:0020037"
                     /description="Cytochrome P450"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1207_0209"
                     /evalue="2.40E-17"
                     /gene_ontologies="GO:0004497: monooxygenase activity"
                     /gene_ontologies="GO:0005506: iron ion binding"
                     /gene_ontologies="GO:0016705: oxidoreductase activity,
                     acting on paired donors, with incorporation or reduction of
                     molecular oxygen"
                     /gene_ontologies="GO:0020037: heme binding"
                     /label="SCO1207"
                     /locus_tag="SCO1207"
                     /protein_end="372"
                     /protein_start="276"
                     /score="63.0"
                     /tool="antismash"
                     /translation="AIDELLRWIPHRNAVGLSRIALEDVEIKGVRIRAGDAVYVSYLAA
                     NRDPEVFPDPDRIDFERSPNPHVSFGFGPHYCPGGMLARLESELLVDAVLD"
     misc_feature    22157..22186
                     /gene_synonym="2SCG58.07"
                     /locus_tag="SCO1207"
                     /note="PS00086 Cytochrome P450 cysteine heme-iron ligand
                     signature"
     gene            22333..22866
                     /db_xref="GeneID:1096631"
                     /gene_synonym="2SCG58.08"
                     /locus_tag="SCO1208"
     CDS             22333..22866
                     /codon_start=1
                     /db_xref="GeneID:1096631"
                     /gene_synonym="2SCG58.08"
                     /locus_tag="SCO1208"
                     /note="2SCG58.08, hypothetical protein, len: 177 aa;
                     similar to TR:CAB92104 (EMBL:AL356334) Streptomyces
                     coelicolor hypothetical 21.7 kD protein SCD69.03, 200 aa;
                     fasta scores: opt: 195 z-score: 238.2 E(): 8.4e-06; 31.7%
                     identity in 164 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_625497.1"
                     /transl_table=11
                     /translation="MSGLVAAAEGLLVPPGQGRVVQAPAQHVTFKVTGSHSRMASTFEV
                     IVPPGFDVGAHVHSRSEELFYVLEGELDVLAFEPRIRTPDSWREWESTSGNRVVRATPG
                     TVIVVPPGCPHAFANPTGEPAKMFFQASPPPDHERYFEELLEILGEGGPPDHEAIEALR
                     AKYDIEQLTPLRHG"
     PFAM_domain     22393..22749
                     /aSDomain="Cupin_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00190.25"
                     /description="Cupin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1208_0210"
                     /evalue="1.40E-18"
                     /label="SCO1208"
                     /locus_tag="SCO1208"
                     /protein_end="139"
                     /protein_start="20"
                     /score="67.0"
                     /tool="antismash"
                     /translation="VQAPAQHVTFKVTGSHSRMASTFEVIVPPGFDVGAHVHSRSEELF
                     YVLEGELDVLAFEPRIRTPDSWREWESTSGNRVVRATPGTVIVVPPGCPHAFANPTGEP
                     AKMFFQASPPPDHER"
     gene            complement(22863..24089)
                     /db_xref="GeneID:1096632"
                     /gene_synonym="2SCG58.09c"
                     /locus_tag="SCO1209"
     CDS             complement(22863..24089)
                     /codon_start=1
                     /db_xref="GeneID:1096632"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 324.9; E-value:
                     1.2e-98)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="2SCG58.09c"
                     /locus_tag="SCO1209"
                     /note="2SCG58.09c, probable acyl-CoA dehydrogenase, len:
                     408 aa; similar to SW:ACDA_BACSU (EMBL:Z49782) Bacillus
                     subtilis acyl-CoA dehydrogenase (EC 1.3.99.-) AcdA, 379 aa;
                     fasta scores: opt: 512 z-score: 587.6 E(): 2.9e-25; 41.3%
                     identity in 400 aa overlap. Contains 2x Pfam matches to
                     entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase and match
                     to Prosite entry PS00073 Acyl-CoA dehydrogenases signature
                     2"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="NP_625498.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.7e-15, bitscore:
                     56.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.7e-25, bitscore:
                     87.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4e-52, bitscore:
                     175.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEFTMELSDEQKEVRDWLHGFAADVIRPAAAEWDEREETPWPVI
                     QEAAKVGIYSLDFYAQQYFDSTGLGIPMAMEELFWGDAGIALSIVGTGLAAVGVLANGT
                     EEQIGTWIPQMYGDANDVKVAAFCSSEPDAGSDVASMRTRAVYDEAKDEWVLNGTKTWA
                     TNGGIANVHVVVAVVDPDLGSKGHASFIVPPATPGLSQGQKFKKHGIRASHTAEVVLDN
                     VRVPGSCLLGGKEKLDARLARAREKAKKGGERVKNAAMATFEASRPAVGAMAVGTARAA
                     YEVALEYAQTREQFGRPIIDNQGVAFQLADMRTSIDAARLLVWRASWMAINGKPFTAAE
                     GSMSKLFASETAKKVTAQAVQILGGNGYTREYPVERMHRDSAIYTIFEGTSEIQRLVIA
                     RTLAGMPIR"
     PFAM_domain     complement(22884..23318)
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00441.27"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1209_0213"
                     /evalue="1.00E-51"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO1209"
                     /locus_tag="SCO1209"
                     /protein_end="402"
                     /protein_start="257"
                     /score="175.2"
                     /tool="antismash"
                     /translation="AAMATFEASRPAVGAMAVGTARAAYEVALEYAQTREQFGRPIIDN
                     QGVAFQLADMRTSIDAARLLVWRASWMAINGKPFTAAEGSMSKLFASETAKKVTAQAVQ
                     ILGGNGYTREYPVERMHRDSAIYTIFEGTSEIQRLVIARTL"
     misc_feature    complement(22890..23315)
                     /gene_synonym="2SCG58.09c"
                     /locus_tag="SCO1209"
                     /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA
                     dehydrogenase, score 208.00, E-value 3.4e-60"
     misc_feature    complement(22950..23009)
                     /gene_synonym="2SCG58.09c"
                     /locus_tag="SCO1209"
                     /note="PS00073 Acyl-CoA dehydrogenases signature 2"
     misc_feature    complement(23391..24068)
                     /gene_synonym="2SCG58.09c"
                     /locus_tag="SCO1209"
                     /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA
                     dehydrogenase, score 170.00, E-value 4.8e-49"
     PFAM_domain     complement(23421..23714)
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02770.22"
                     /db_xref="GO:0016627"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1209_0212"
                     /evalue="1.30E-24"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /label="SCO1209"
                     /locus_tag="SCO1209"
                     /protein_end="223"
                     /protein_start="125"
                     /score="86.3"
                     /tool="antismash"
                     /translation="AFCSSEPDAGSDVASMRTRAVYDEAKDEWVLNGTKTWATNGGIAN
                     VHVVVAVVDPDLGSKGHASFIVPPATPGLSQGQKFKKHGIRASHTAEVVLDNV"
     PFAM_domain     complement(23745..24065)
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02771.19"
                     /db_xref="GO:0016627"
                     /db_xref="GO:0050660"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1209_0211"
                     /evalue="2.20E-14"
                     /gene_ontologies="GO:0016627: oxidoreductase activity,
                     acting on the CH-CH group of donors"
                     /gene_ontologies="GO:0050660: flavin adenine dinucleotide
                     binding"
                     /label="SCO1209"
                     /locus_tag="SCO1209"
                     /protein_end="115"
                     /protein_start="8"
                     /score="54.2"
                     /tool="antismash"
                     /translation="SDEQKEVRDWLHGFAADVIRPAAAEWDEREETPWPVIQEAAKVGI
                     YSLDFYAQQYFDSTGLGIPMAMEELFWGDAGIALSIVGTGLAAVGVLANGTEEQIGTWI
                     PQM"
     regulatory      complement(24094..24098)
                     /regulatory_class="ribosome_binding_site"
     regulatory      24251..24254
                     /regulatory_class="ribosome_binding_site"
     gene            24260..24916
                     /db_xref="GeneID:1096633"
                     /gene_synonym="2SCG58.10"
                     /locus_tag="SCO1210"
     CDS             24260..24916
                     /codon_start=1
                     /db_xref="GeneID:1096633"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 181.3; E-value: 4.2e-55)"
                     /gene_kind="regulatory"
                     /gene_synonym="2SCG58.10"
                     /locus_tag="SCO1210"
                     /note="2SCG58.10, probable transcriptional regulatory
                     protein, len: 218 aa; similar to TR:O53757 (EMBL:AL021933)
                     Mycobacterium tuberculosis regulatory protein MTV038.16c,
                     234 aa; fasta scores: opt: 214 z-score: 258.1 E(): 6.5e-07;
                     30.7% identity in 199 aa overlap. Contains Pfam match to
                     entry PF00440 tetR, Bacterial regulatory proteins, tetR
                     family and possible helix-turn-helix motif at residues
                     35..56 (+3.27 SD)"
                     /product="transcriptional regulator"
                     /protein_id="NP_625499.1"
                     /transl_table=11
                     /translation="MNTTQRADQQTSADRRRRELLEAADRVVLRDGPHASMNAIAAEAG
                     ITKPILYRHFGDKGGLYAALAVRHTDALLASLRAALDAPAQRRQRVEATLDTYLAAIEA
                     RPQVYRFLMHPAESAGTPGDQSEQGFDVGKHSAPLLRRMGEELAQVIEERLDVGPGTQQ
                     LARVWGHGIVGMMHAAGDWWLGERPCPREELVRTLADLLWGRLAEAGDKEGGPGF"
     misc_feature    24317..24454
                     /gene_synonym="2SCG58.10"
                     /locus_tag="SCO1210"
                     /note="Pfam match to entry PF00440 tetR, Bacterial
                     regulatory proteins, tetR family, score 52.90, E-value
                     4.2e-12"
     PFAM_domain     24317..24454
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00440.26"
                     /db_xref="GO:0003677"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1210_0214"
                     /evalue="8.10E-12"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /label="SCO1210"
                     /locus_tag="SCO1210"
                     /protein_end="65"
                     /protein_start="19"
                     /score="44.9"
                     /tool="antismash"
                     /translation="LLEAADRVVLRDGPHASMNAIAAEAGITKPILYRHFGDKGGLYAA
                     L"
     PFAM_domain     24485..24913
                     /aSDomain="TetR_C_32"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19344.2"
                     /description="Tetracyclin repressor-like, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1210_0215"
                     /evalue="2.10E-75"
                     /label="SCO1210"
                     /locus_tag="SCO1210"
                     /protein_end="218"
                     /protein_start="75"
                     /score="251.5"
                     /tool="antismash"
                     /translation="SLRAALDAPAQRRQRVEATLDTYLAAIEARPQVYRFLMHPAESAG
                     TPGDQSEQGFDVGKHSAPLLRRMGEELAQVIEERLDVGPGTQQLARVWGHGIVGMMHAA
                     GDWWLGERPCPREELVRTLADLLWGRLAEAGDKEGGPGF"
     gene            complement(24958..25611)
                     /db_xref="GeneID:1096634"
                     /gene_synonym="2SCG58.11c"
                     /locus_tag="SCO1211"
     CDS             complement(24958..25611)
                     /codon_start=1
                     /db_xref="GeneID:1096634"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275:peptide deformylase (Score: 206.6; E-value:
                     2.7e-63)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="2SCG58.11c"
                     /locus_tag="SCO1211"
                     /note="2SCG58.11c, probable polypeptide deformylase, len:
                     217 aa; similar to SW:DEF_STRCO (EMBL:AL078618)
                     Streptomyces coelicolor polypeptide deformylase (EC
                     3.5.1.31) Def or SC10A7.23, 208 aa; fasta scores: opt: 594
                     z-score: 712.9 E(): 3.1e-32; 54.2% identity in 166 aa
                     overlap and to SW:DEF_ECOLI (EMBL:X77800) Escherichia coli
                     polypeptide deformylase (EC 3.5.1.31) Def, 168 aa; fasta
                     scores: opt: 321 z-score: 391.3 E(): 2.5e-14; 34.2%
                     identity in 155 aa overlap. Contains Pfam match to entry
                     PF01327 Pep_deformylase, Polypeptide deformylase"
                     /product="polypeptide deformylase"
                     /protein_id="NP_625500.1"
                     /transl_table=11
                     /translation="MWTSAYRDPFALPNRGTGHRFRRWAPAAGGHRDLTLTAMRQGSIP
                     GAHGRVRPLGLLGDPVLHARCAEVTDFGPELAALVEDLFATMYAAHGVGLAANQVGEAV
                     RVFVYDCPDDEDERHLGHVVNPRLVETGGVVVRGPEGCLSLPGLEAGTERYDEAVVTGF
                     TVAGEPVTVRGTGFFARCLQHECDHLEGRVYADRLTGRRHRKLMRQVARASWHR"
     aSDomain        complement(24994..25440)
                     /aSDomain="TIGR00079"
                     /aSTool="tigrfam"
                     /description="pept_deformyl: peptide deformylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO1211_0018"
                     /evalue="2.60E-35"
                     /identifier="TIGR00079"
                     /label="SCO1211"
                     /locus_tag="SCO1211"
                     /protein_end="206"
                     /protein_start="57"
                     /score="119.3"
                     /tool="antismash"
                     /translation="GDPVLHARCAEVTDFGPELAALVEDLFATMYAAHGVGLAANQVGE
                     AVRVFVYDCPDDEDERHLGHVVNPRLVETGGVVVRGPEGCLSLPGLEAGTERYDEAVVT
                     GFTVAGEPVTVRGTGFFARCLQHECDHLEGRVYADRLTGRRHRKL"
     PFAM_domain     complement(25009..25446)
                     /aSDomain="Pep_deformylase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01327.24"
                     /db_xref="GO:0042586"
                     /description="Polypeptide deformylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1211_0216"
                     /evalue="5.40E-42"
                     /gene_ontologies="GO:0042586: peptide deformylase activity"
                     /label="SCO1211"
                     /locus_tag="SCO1211"
                     /protein_end="201"
                     /protein_start="55"
                     /score="143.2"
                     /tool="antismash"
                     /translation="LLGDPVLHARCAEVTDFGPELAALVEDLFATMYAAHGVGLAANQV
                     GEAVRVFVYDCPDDEDERHLGHVVNPRLVETGGVVVRGPEGCLSLPGLEAGTERYDEAV
                     VTGFTVAGEPVTVRGTGFFARCLQHECDHLEGRVYADRLTGR"
     misc_feature    complement(25030..25455)
                     /gene_synonym="2SCG58.11c"
                     /locus_tag="SCO1211"
                     /note="Pfam match to entry PF01327 Pep_deformylase,
                     Polypeptide deformylase, score 171.50, E-value 1.4e-47"
     misc_feature    complement(25600..25615)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.03"
                     /tool="antismash"
     regulatory      25659..25664
                     /regulatory_class="ribosome_binding_site"
     gene            25676..26914
                     /db_xref="GeneID:1096635"
                     /gene_synonym="2SCG58.12"
                     /locus_tag="SCO1212"
     CDS             25676..26914
                     /codon_start=1
                     /db_xref="GeneID:1096635"
                     /gene_synonym="2SCG58.12"
                     /locus_tag="SCO1212"
                     /note="2SCG58.12, possible ligase, len: 412 aa; similar to
                     TR:Q9ZGG7 (EMBL:AF080002) Heliobacillus mobilis
                     UDP-N-acetylmuramyl tripeptide synthetase MurC, 455 aa;
                     fasta scores: opt: 261 z-score: 287.4 E(): 1.5e-08; 29.3%
                     identity in 441 aa overlap. Contains Pfam match to entry
                     PF01225 Mur_ligase, Mur ligase family"
                     /product="ligase"
                     /protein_id="NP_625501.1"
                     /transl_table=11
                     /translation="MAGNSDPLTPRAKIAVTAGKAVAAASRAAGRGSGSVIGGRVALKL
                     DPDLLGRLAGHLDVTLVSATNGKTTTTRLIAEALKAAGPVVSNALGANMPAGITSALAG
                     GADARYGVIEVDEKYLVGVAQATDPKCIALLNLSRDQLDRAAETRMLAENWREGLAGSK
                     AVVVANADDPLVVWAASSSPNVIWVAAGQMWKDDAWSCPSCGGVMQRPGDDWFCGECGF
                     RRPTPSWALSGDHVLDPHGSAWPIHLQLPGRANKANAASSAAVAAVFGVPPQVALERMY
                     QVQAVAGRYDVVQFQGRDLRLLLAKNPAGWLETFSLIDPPPAPVILSVNARGADGTDTS
                     WLWDVDYTRLSGHPICVVGDRKLDLAVRLEVANQQFQVCEDLDQAVQLCPPGRIEVIAN
                     YTAFQDLRRRVGN"
     misc_feature    25850..26599
                     /gene_synonym="2SCG58.12"
                     /locus_tag="SCO1212"
                     /note="Pfam match to entry PF01225 Mur_ligase, Mur ligase
                     family, score 32.70, E-value 4.3e-09"
     PFAM_domain     25868..26473
                     /aSDomain="Mur_ligase_M"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08245.15"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0009058"
                     /db_xref="GO:0016881"
                     /description="Mur ligase middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1212_0217"
                     /evalue="2.30E-11"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0009058: biosynthetic process"
                     /gene_ontologies="GO:0016881: acid-amino acid ligase
                     activity"
                     /label="SCO1212"
                     /locus_tag="SCO1212"
                     /protein_end="266"
                     /protein_start="64"
                     /score="44.2"
                     /tool="antismash"
                     /translation="TNGKTTTTRLIAEALKAAGPVVSNALGANMPAGITSALAGGADAR
                     YGVIEVDEKYLVGVAQATDPKCIALLNLSRDQLDRAAETRMLAENWREGLAGSKAVVVA
                     NADDPLVVWAASSSPNVIWVAAGQMWKDDAWSCPSCGGVMQRPGDDWFCGECGFRRPTP
                     SWALSGDHVLDPHGSAWPIHLQLPGRANKANAASSAAVA"
     PFAM_domain     26585..26884
                     /aSDomain="MurT_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08353.13"
                     /description="MurT ligase C-terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1212_0218"
                     /evalue="1.10E-21"
                     /label="SCO1212"
                     /locus_tag="SCO1212"
                     /protein_end="403"
                     /protein_start="303"
                     /score="77.0"
                     /tool="antismash"
                     /translation="LAKNPAGWLETFSLIDPPPAPVILSVNARGADGTDTSWLWDVDYT
                     RLSGHPICVVGDRKLDLAVRLEVANQQFQVCEDLDQAVQLCPPGRIEVIANYTAF"
     gene            26938..27666
                     /db_xref="GeneID:1096636"
                     /gene_synonym="2SCG58.13"
                     /locus_tag="SCO1213"
     CDS             26938..27666
                     /codon_start=1
                     /db_xref="GeneID:1096636"
                     /gene_synonym="2SCG58.13"
                     /locus_tag="SCO1213"
                     /note="2SCG58.13, hypotetical protein, len: 242 aa; similar
                     to TR:Q9ZGG8 (EMBL:AF080002) Heliobacillus mobilis cobyric
                     acid synthase CobQ, 252 aa; fasta scores: opt: 505 z-score:
                     574.8 E(): 1.5e-24; 39.5% identity in 238 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_625502.1"
                     /transl_table=11
                     /translation="MSDNQLRIVWIYPDLLSTYGDQGNALVVERRARQRGLDVARLDVR
                     SDQPIPTSGDIYLVGGGEDRPQRLAAERLRRDGGLYRAVENGAIVFSVCAGYQILGHEF
                     INDLGQREPGLGLLDVVSTRGEGARCVGDVLGDIDPRLGLPPLTGFENHQGVTHVGPNA
                     RPLAQVRFGNGNGTGDGTEGAYNDTVFGTYMHGPVLARNPLIADLLLKLALDVNALPPT
                     DDRWYEALRNERIAAAQQPA"
     PFAM_domain     26956..27543
                     /aSDomain="GATase_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07685.17"
                     /db_xref="GO:0003824"
                     /description="CobB/CobQ-like glutamine amidotransferase
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1213_0219"
                     /evalue="4.10E-37"
                     /gene_ontologies="GO:0003824: catalytic activity"
                     /label="SCO1213"
                     /locus_tag="SCO1213"
                     /protein_end="202"
                     /protein_start="6"
                     /score="127.8"
                     /tool="antismash"
                     /translation="RIVWIYPDLLSTYGDQGNALVVERRARQRGLDVARLDVRSDQPIP
                     TSGDIYLVGGGEDRPQRLAAERLRRDGGLYRAVENGAIVFSVCAGYQILGHEFINDLGQ
                     REPGLGLLDVVSTRGEGARCVGDVLGDIDPRLGLPPLTGFENHQGVTHVGPNARPLAQV
                     RFGNGNGTGDGTEGAYNDTVFGTYMHGPVLARN"
     gene            27833..28858
                     /db_xref="GeneID:1096637"
                     /gene_synonym="2SCG58.14; pfkA3"
                     /locus_tag="SCO1214"
     CDS             27833..28858
                     /codon_start=1
                     /db_xref="GeneID:1096637"
                     /gene_synonym="2SCG58.14; pfkA3"
                     /locus_tag="SCO1214"
                     /note="catalyzes the formation of D-fructose
                     1,6-bisphosphate from D-fructose 6-phosphate in glycolysis"
                     /product="6-phosphofructokinase"
                     /protein_id="NP_625503.1"
                     /transl_table=11
                     /translation="MRIGVLTSGGDCPGLNAVIRSVVHRAVVDHGDEVIGFRDGWKGLL
                     ECDYLKLDLDAVGGILARGGTILGSSRVRPEHLRDGVERARGHVEELGLDAIIPIGGEG
                     TLKAARLLSDNGLPIVGVPKTIDNDIAVTDVTFGFDTAVTVATEALDRLKTTAESHQRV
                     LIVEVMGRHTGWIALHSGMAAGAHAVVVPERPFDIDELTAKVGERFSAGKRFAIVVAAE
                     GAKPKAGTMDFDEGGKDVYGHERFAGIARQLSIELEERLGKEARPVILGHVQRGGTPTA
                     YDRVLATRFGWHAVEAVHRGEFGKMTALRGTDIEMVSLADAVESLKTVPDARYAEAECV
                     L"
     PFAM_domain     27836..28726
                     /aSDomain="PFK"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00365.23"
                     /db_xref="GO:0003872"
                     /db_xref="GO:0006096"
                     /description="Phosphofructokinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1214_0220"
                     /evalue="7.10E-104"
                     /gene_ontologies="GO:0003872: 6-phosphofructokinase
                     activity"
                     /gene_ontologies="GO:0006096: glycolytic process"
                     /label="SCO1214"
                     /locus_tag="SCO1214"
                     /protein_end="298"
                     /protein_start="1"
                     /score="347.2"
                     /tool="antismash"
                     /translation="RIGVLTSGGDCPGLNAVIRSVVHRAVVDHGDEVIGFRDGWKGLLE
                     CDYLKLDLDAVGGILARGGTILGSSRVRPEHLRDGVERARGHVEELGLDAIIPIGGEGT
                     LKAARLLSDNGLPIVGVPKTIDNDIAVTDVTFGFDTAVTVATEALDRLKTTAESHQRVL
                     IVEVMGRHTGWIALHSGMAAGAHAVVVPERPFDIDELTAKVGERFSAGKRFAIVVAAEG
                     AKPKAGTMDFDEGGKDVYGHERFAGIARQLSIELEERLGKEARPVILGHVQRGGTPTAY
                     DRVLATRFGWHAVEAV"
     misc_feature    27836..28732
                     /gene_synonym="2SCG58.14; pfkA3"
                     /locus_tag="SCO1214"
                     /note="Pfam match to entry PF00365 PFK,
                     Phosphofructokinase, score 320.60, E-value 4.5e-117"
     aSDomain        27836..28801
                     /aSDomain="TIGR02483"
                     /aSTool="tigrfam"
                     /description="PFK_mixed: phosphofructokinase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO1214_0019"
                     /evalue="3.00E-150"
                     /identifier="TIGR02483"
                     /label="SCO1214"
                     /locus_tag="SCO1214"
                     /protein_end="323"
                     /protein_start="1"
                     /score="497.7"
                     /tool="antismash"
                     /translation="RIGVLTSGGDCPGLNAVIRSVVHRAVVDHGDEVIGFRDGWKGLLE
                     CDYLKLDLDAVGGILARGGTILGSSRVRPEHLRDGVERARGHVEELGLDAIIPIGGEGT
                     LKAARLLSDNGLPIVGVPKTIDNDIAVTDVTFGFDTAVTVATEALDRLKTTAESHQRVL
                     IVEVMGRHTGWIALHSGMAAGAHAVVVPERPFDIDELTAKVGERFSAGKRFAIVVAAEG
                     AKPKAGTMDFDEGGKDVYGHERFAGIARQLSIELEERLGKEARPVILGHVQRGGTPTAY
                     DRVLATRFGWHAVEAVHRGEFGKMTALRGTDIEMVSLADAV"
     misc_feature    28628..28684
                     /gene_synonym="2SCG58.14; pfkA3"
                     /locus_tag="SCO1214"
                     /note="PS00433 Phosphofructokinase signature"
     regulatory      29039..29044
                     /regulatory_class="ribosome_binding_site"
     gene            29052..30002
                     /db_xref="GeneID:1096638"
                     /gene_synonym="2SCG58.15"
                     /locus_tag="SCO1215"
     CDS             29052..30002
                     /codon_start=1
                     /db_xref="GeneID:1096638"
                     /gene_synonym="2SCG58.15"
                     /locus_tag="SCO1215"
                     /note="2SCG58.15, possible integral membrane protein, len:
                     316 aa; similar to SW:CTAG_BACSU (EMBL:Z98682) Bacillus
                     subtilis CtaG protein, 297 aa; fasta scores: opt: 139
                     z-score: 169.9 E(): 0.053; 24.7% identity in 292 aa
                     overlap. Contains possible hydrophobic membrane spanning
                     regions"
                     /product="hypothetical protein"
                     /protein_id="NP_625504.1"
                     /transl_table=11
                     /translation="MDHSGHGMTMDLPPFTLGRGLAWSADPFFLVACLLGLALYGWGVA
                     RLVRRGDKWPVGRTVAFVAGVLSVALMMCTKLNDYGMVMFSVHMVQHMVISMVSPILLL
                     LGAPITLALRALPPAGRGRKGPRELLLMLLHSRYMRIITHPAFTIPLFIASLYALYFTP
                     LFDTLMGSQAGHIGMMVHFLAVGVVFFWPIMGVDPGPHRPGYLMRMLELFAGMPFHAFF
                     GIALMMASSPMVETFKNPPASLGIDALSDQNAAGGIAWAFSEVPSVLVLLALLFQWYAS
                     EERQARRSDRAADRDGDKELAAYNAYLASLNTRGG"
     PFAM_domain     29163..29891
                     /aSDomain="Caa3_CtaG"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF09678.13"
                     /description="Cytochrome c oxidase caa3 assembly factor
                     (Caa3_CtaG)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1215_0221"
                     /evalue="3.10E-83"
                     /label="SCO1215"
                     /locus_tag="SCO1215"
                     /protein_end="280"
                     /protein_start="37"
                     /score="278.9"
                     /tool="antismash"
                     /translation="ALYGWGVARLVRRGDKWPVGRTVAFVAGVLSVALMMCTKLNDYGM
                     VMFSVHMVQHMVISMVSPILLLLGAPITLALRALPPAGRGRKGPRELLLMLLHSRYMRI
                     ITHPAFTIPLFIASLYALYFTPLFDTLMGSQAGHIGMMVHFLAVGVVFFWPIMGVDPGP
                     HRPGYLMRMLELFAGMPFHAFFGIALMMASSPMVETFKNPPASLGIDALSDQNAAGGIA
                     WAFSEVPSVLVLLALLFQWYA"
     gene            30013..30216
                     /db_xref="GeneID:1096639"
                     /gene_synonym="2SCG58.16"
                     /locus_tag="SCO1216"
     CDS             30013..30216
                     /codon_start=1
                     /db_xref="GeneID:1096639"
                     /gene_synonym="2SCG58.16"
                     /locus_tag="SCO1216"
                     /note="2SCG58.16, possible integral membrane protein, len:
                     67 aa. Contains possible hydrophobic membrane spanning
                     regions"
                     /product="hypothetical protein"
                     /protein_id="NP_625505.1"
                     /transl_table=11
                     /translation="MEGNGHEEGVAMPGSTDSSTKTMGALTIGGLVAVTAYTVALGSNG
                     WLWFGWVVLGLITLGLVATRSA"
     gene            complement(30255..31472)
                     /db_xref="GeneID:1096640"
                     /gene_synonym="2SCG58.17c"
                     /locus_tag="SCO1217"
     CDS             complement(30255..31472)
                     /codon_start=1
                     /db_xref="GeneID:1096640"
                     /gene_synonym="2SCG58.17c"
                     /locus_tag="SCO1217"
                     /note="2SCG58.17c, possible sensor kinase, len: 405 aa;
                     similar to TR:AAF31453 (EMBL:AF221126) Streptococcus
                     pneumoniae histidine kinase ZmpS, 563 aa; fasta scores:
                     opt: 375 z-score: 453.5 E(): 8.6e-18; 26.7% identity in 363
                     aa overlap. Contains Pfam match to entry PF00512 signal,
                     Histidine kinase and possible N-terminal region signal
                     peptide sequence (possibly cleavable)"
                     /product="sensor kinase"
                     /protein_id="NP_625506.1"
                     /transl_table=11
                     /translation="MSGSVGGFLAGLAVALLPLLAAGFWLGRRTARPQHLGGLGTPVEH
                     ATFQTLHTASLATPPLRAGLTEETAGKSARKLRSLLGTDALCLTDLEEVLVWDGVGNHH
                     RAEIMERLAGPLSTGRGEAFRLSCDTPDCTVRWAVVAPLTVDDRVHGALVACAPRESAV
                     LVRAAGEVARWVSVQLELADLDQSRTRLIEAEIKALRAQISPHFIFNSLAVIASFVRTD
                     PERARELLLEFADFTRYSFRRHGDFTTLADELHAIDHYLALVRARFGDRLAVTLQVAPE
                     VLPVALPFLCLQPLVENAVKHGLEGKADRCRIQITAQDAGAEALVVIEDDGAGMDPDLL
                     RRILAREVSPSGGIGLSNVDDRLRQVYGDAHGLVIETAVGAGMKITVRLPKYQPGVHSA
                     GRLGRD"
     PFAM_domain     complement(30300..30599)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02518.29"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1217_0223"
                     /evalue="3.40E-09"
                     /label="SCO1217"
                     /locus_tag="SCO1217"
                     /protein_end="391"
                     /protein_start="291"
                     /score="37.3"
                     /tool="antismash"
                     /translation="LQPLVENAVKHGLEGKADRCRIQITAQDAGAEALVVIEDDGAGMD
                     PDLLRRILAREVSPSGGIGLSNVDDRLRQVYGDAHGLVIETAVGAGMKITVRLPK"
     misc_feature    complement(30303..30902)
                     /gene_synonym="2SCG58.17c"
                     /locus_tag="SCO1217"
                     /note="Pfam match to entry PF00512 signal, Histidine
                     kinase, score -31.20, E-value 0.0023"
     PFAM_domain     complement(30657..30893)
                     /aSDomain="His_kinase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF06580.16"
                     /db_xref="GO:0000155"
                     /db_xref="GO:0000160"
                     /db_xref="GO:0016020"
                     /description="Histidine kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1217_0222"
                     /evalue="4.70E-23"
                     /gene_ontologies="GO:0000155: phosphorelay sensor kinase
                     activity"
                     /gene_ontologies="GO:0000160: phosphorelay signal
                     transduction system"
                     /gene_ontologies="GO:0016020: membrane"
                     /label="SCO1217"
                     /locus_tag="SCO1217"
                     /protein_end="272"
                     /protein_start="193"
                     /score="81.4"
                     /tool="antismash"
                     /translation="AEIKALRAQISPHFIFNSLAVIASFVRTDPERARELLLEFADFTR
                     YSFRRHGDFTTLADELHAIDHYLALVRARFGDRL"
     gene            complement(31469..33304)
                     /db_xref="GeneID:1096641"
                     /gene_synonym="2SCG58.18c"
                     /locus_tag="SCO1218"
     CDS             complement(31469..33304)
                     /codon_start=1
                     /db_xref="GeneID:1096641"
                     /gene_synonym="2SCG58.18c"
                     /locus_tag="SCO1218"
                     /note="2SCG58.18c, possible transmembrane transport
                     protein, len: 611 aa; similar to TR:Q9RX38 (EMBL:AE001907)
                     Deinococcus radiodurans sodium:solute symporter protein
                     DR0477, 528 aa; fasta scores: opt: 379 z-score: 407.0 E():
                     3.3e-15; 30.5% identity in 564 aa overlap. Contains Pfam
                     match to entry PF00474 SSF, Sodium:solute symporter family
                     and match to Prosite entry PS00457 Sodium:solute symporter
                     family signature 2. Also contains possible hydrophobic
                     membrane spanning regions and 4x conserved repeat unit:
                     RTDLL"
                     /product="transmembrane transport protein"
                     /protein_id="NP_625507.1"
                     /transl_table=11
                     /translation="MNSSYAIPAVALVVVATVLVGAFGLRISRTTSDFYVASRTVGPRL
                     NAAAISGEYLSAASFLGIAGLVLVQGPDMLWYPVGYTAGYLVLLLFVAAPLRRSGAYTL
                     PDFAEARLASQGVRRLAGAFVVGVGWLYLLPQLQGAGLTLTVLSGAPDWLGGVIVAVVV
                     AAIVAAGGMRSITFVQAFQFWLKLTALLVPALFLVLAWQGDGAPGRPFDEPATFREQRS
                     VRVDDSLTLKLEEPLTVTVDGTVDGRAHDGDRVALPAGTHRIEAGARLTFAAHTPVPAA
                     GRGADDALSPSRAESRTERPLYATYGLILATFLGTMGLPHVVVRFYTSPTGVAARRTTV
                     AVLGLIGAFYLLPPLYGALGRLYAPELTLTGDADAAVLLLPDRVIGGVGGDLLGALVAG
                     GAFAAFLSTASGLTMAVAGVLTQDVLPSRAVPHFRLGTLLAMAVPLAASALVGGLPVAD
                     AVGLAFAVSASSFCPLLVLGIWWRRLTPPGAAAGMLVGGGSALLAVAATMGGFPGGGGS
                     LHALLAWPALWSVPLGFLTMVLVSLATPGRVPAGTAAILARFHLPEELHAEELRTDDLR
                     TDDLRTDDLRTDDLETAADLPEVREVRDVREEPTR"
     regulatory      complement(31481..31486)
                     /gene_synonym="2SCG58.18c"
                     /locus_tag="SCO1218"
                     /regulatory_class="ribosome_binding_site"
     repeat_region   complement(31535..31594)
                     /gene_synonym="2SCG58.18c"
                     /locus_tag="SCO1218"
                     /note="4x conserved repeat unit translated in SCG58.18c"
     misc_feature    complement(31811..31873)
                     /gene_synonym="2SCG58.18c"
                     /locus_tag="SCO1218"
                     /note="PS00457 Sodium:solute symporter family signature 2"
     PFAM_domain     complement(31817..32383)
                     /aSDomain="SSF"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00474.20"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Sodium:solute symporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1218_0225"
                     /evalue="4.40E-12"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO1218"
                     /locus_tag="SCO1218"
                     /protein_end="496"
                     /protein_start="307"
                     /score="45.7"
                     /tool="antismash"
                     /translation="LILATFLGTMGLPHVVVRFYTSPTGVAARRTTVAVLGLIGAFYLL
                     PPLYGALGRLYAPELTLTGDADAAVLLLPDRVIGGVGGDLLGALVAGGAFAAFLSTASG
                     LTMAVAGVLTQDVLPSRAVPHFRLGTLLAMAVPLAASALVGGLPVADAVGLAFAVSASS
                     FCPLLVLGIWWRRLTPPGAAAGMLVG"
     misc_feature    complement(31817..33205)
                     /gene_synonym="2SCG58.18c"
                     /locus_tag="SCO1218"
                     /note="Pfam match to entry PF00474 SSF, Sodium:solute
                     symporter family, score 22.70, E-value 1.3e-08"
     PFAM_domain     complement(32711..33205)
                     /aSDomain="SSF"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00474.20"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Sodium:solute symporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1218_0224"
                     /evalue="1.30E-20"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO1218"
                     /locus_tag="SCO1218"
                     /protein_end="198"
                     /protein_start="33"
                     /score="73.8"
                     /tool="antismash"
                     /translation="FYVASRTVGPRLNAAAISGEYLSAASFLGIAGLVLVQGPDMLWYP
                     VGYTAGYLVLLLFVAAPLRRSGAYTLPDFAEARLASQGVRRLAGAFVVGVGWLYLLPQL
                     QGAGLTLTVLSGAPDWLGGVIVAVVVAAIVAAGGMRSITFVQAFQFWLKLTALLVPALF
                     LV"
     gene            complement(33333..33728)
                     /db_xref="GeneID:1096642"
                     /gene_synonym="2SCG58.19c"
                     /locus_tag="SCO1219"
     CDS             complement(33333..33728)
                     /codon_start=1
                     /db_xref="GeneID:1096642"
                     /gene_synonym="2SCG58.19c"
                     /locus_tag="SCO1219"
                     /note="2SCG58.19c, possible integral membrane protein, len:
                     131 aa. Contains possible hydrophobic membrane spanning
                     regions"
                     /product="hypothetical protein"
                     /protein_id="NP_625508.1"
                     /transl_table=11
                     /translation="MPQDPTERRVTVTGPPRRTVPPARLRSRGRHPQATGHYRPRTEID
                     EQTTLGHTYVRSLMRSQLRAGLTALAVLGLLVGPLPLLFAALPDARRLEWAVLGFGLYA
                     PLVLLARWYVRRAERNERDFVRLVEDR"
     gene            complement(33732..34493)
                     /db_xref="GeneID:1096643"
                     /gene_synonym="2SCG58.20c"
                     /locus_tag="SCO1220"
     CDS             complement(33732..34493)
                     /codon_start=1
                     /db_xref="GeneID:1096643"
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 64.9; E-value:
                     9.7e-20)"
                     /gene_kind="regulatory"
                     /gene_synonym="2SCG58.20c"
                     /locus_tag="SCO1220"
                     /note="2SCG58.20c, probable regulatory protein, len: 253
                     aa; similar to SW:ALGR_PSEAE (EMBL:M23230) Pseudomonas
                     aeruginosa positive alginate biosynthesis regulatory
                     protein AlgR, 248 aa; fasta scores: opt: 384 z-score: 457.3
                     E(): 5.3e-18; 36.5% identity in 255 aa overlap. Contains
                     Pfam match to entry PF00072 response_reg, Response
                     regulator receiver domain"
                     /product="regulatory protein"
                     /protein_id="NP_625509.1"
                     /transl_table=11
                     /translation="MLRALAVDDERPTLEELVYLLNADPRIGTAEGASDTTEALRRINR
                     ALETGPGGPDAIDVVFLDIQMPGLDGLDLARLLTGFARPPLVVFVTAHEDFAVQAFDLK
                     AVDYVLKPVRRERLAEAVRRVAEQRGTAAVPAPRIPVHEPDPDHITVELGGVTRFVPVD
                     EITHVEAQGDYARLHTDRGSHLVRIPLSTLEERWRARGFVRIHRRHLVALRHVGELRLD
                     AGTVSVLVGTEELQVSRRHARELRDLLMRRP"
     regulatory      complement(33738..33742)
                     /gene_synonym="2SCG58.20c"
                     /locus_tag="SCO1220"
                     /regulatory_class="ribosome_binding_site"
     PFAM_domain     complement(33747..34025)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04397.18"
                     /db_xref="GO:0003677"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1220_0227"
                     /evalue="2.80E-21"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /label="SCO1220"
                     /locus_tag="SCO1220"
                     /protein_end="249"
                     /protein_start="156"
                     /score="75.7"
                     /tool="antismash"
                     /translation="TRFVPVDEITHVEAQGDYARLHTDRGSHLVRIPLSTLEERWRARG
                     FVRIHRRHLVALRHVGELRLDAGTVSVLVGTEELQVSRRHARELRDLL"
     PFAM_domain     complement(34125..34481)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00072.27"
                     /db_xref="GO:0000160"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1220_0226"
                     /evalue="1.80E-18"
                     /gene_ontologies="GO:0000160: phosphorelay signal
                     transduction system"
                     /label="SCO1220"
                     /locus_tag="SCO1220"
                     /protein_end="123"
                     /protein_start="4"
                     /score="66.8"
                     /tool="antismash"
                     /translation="LAVDDERPTLEELVYLLNADPRIGTAEGASDTTEALRRINRALET
                     GPGGPDAIDVVFLDIQMPGLDGLDLARLLTGFARPPLVVFVTAHEDFAVQAFDLKAVDY
                     VLKPVRRERLAEAVR"
     misc_feature    complement(34128..34490)
                     /gene_synonym="2SCG58.20c"
                     /locus_tag="SCO1220"
                     /note="Pfam match to entry PF00072 response_reg, Response
                     regulator receiver domain, score 90.60, E-value 3.2e-23"
     gene            34571..35074
                     /db_xref="GeneID:1096644"
                     /gene_synonym="2SCG58.21"
                     /locus_tag="SCO1221"
     CDS             34571..35074
                     /codon_start=1
                     /db_xref="GeneID:1096644"
                     /gene_functions="regulatory (smcogs) SMCOG1120:AsnC family
                     transcriptional regulator (Score: 168.1; E-value: 1.6e-51)"
                     /gene_kind="regulatory"
                     /gene_synonym="2SCG58.21"
                     /locus_tag="SCO1221"
                     /note="2SCG58.21, possible AsnC-family regulatory protein,
                     len: 167 aa; similar to SW:PUTR_RHOCA (EMBL:X78346)
                     Rhodobacter capsulatus proline dehydrogenase
                     transcriptional activator PutR, 154 aa; fasta scores: opt:
                     248 z-score: 311.6 E(): 6.9e-10; 31.3% identity in 147 aa
                     overlap. Contains Pfam match to entry PF01037
                     ASNC_trans_reg, AsnC family"
                     /product="transcription regulator AsnC"
                     /protein_id="NP_625510.1"
                     /transl_table=11
                     /translation="MNSRPASFDELDRKIVTALMENARTSFAEIGAEIGLSSTAVKRRV
                     DRLRETDVITGFSATVRPSALGWRTEAYVEVYCEGAAPPRRLAEVVRGYPEITAAMTVT
                     GGADALLHVRARDVEHFEEVLERIRAEPFIRKTISVMVLSHLIPDSPEAGAALLAPKDA
                     ADVR"
     PFAM_domain     34595..34717
                     /aSDomain="HTH_AsnC-type"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13404.9"
                     /db_xref="GO:0043565"
                     /description="AsnC-type helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1221_0228"
                     /evalue="8.80E-17"
                     /gene_ontologies="GO:0043565: sequence-specific DNA
                     binding"
                     /label="SCO1221"
                     /locus_tag="SCO1221"
                     /protein_end="49"
                     /protein_start="8"
                     /score="60.8"
                     /tool="antismash"
                     /translation="DELDRKIVTALMENARTSFAEIGAEIGLSSTAVKRRVDRLR"
     misc_feature    34664..34966
                     /gene_synonym="2SCG58.21"
                     /locus_tag="SCO1221"
                     /note="Pfam match to entry PF01037 ASNC_trans_reg, AsnC
                     family, score 66.80, E-value 4.5e-16"
     PFAM_domain     34790..35002
                     /aSDomain="AsnC_trans_reg"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01037.24"
                     /description="Lrp/AsnC ligand binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1221_0229"
                     /evalue="3.80E-15"
                     /label="SCO1221"
                     /locus_tag="SCO1221"
                     /protein_end="144"
                     /protein_start="73"
                     /score="55.7"
                     /tool="antismash"
                     /translation="VEVYCEGAAPPRRLAEVVRGYPEITAAMTVTGGADALLHVRARDV
                     EHFEEVLERIRAEPFIRKTISVMVLS"
     misc_feature    35167..35180
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.65"
                     /tool="antismash"
     regulatory      35186..35191
                     /regulatory_class="ribosome_binding_site"
     gene            35200..36066
                     /db_xref="GeneID:1096645"
                     /gene_synonym="2SCG58.22"
                     /locus_tag="SCO1222"
     CDS             35200..36066
                     /codon_start=1
                     /db_xref="GeneID:1096645"
                     /gene_synonym="2SCG58.22"
                     /locus_tag="SCO1222"
                     /note="2SCG58.22, conserved hypothetical protein, len: 288
                     aa; similar to TR:P71889 (EMBL:Z79702) Mycobacterium
                     tuberculosis hypothetical 33.0 kD protein MTCY3G12.11, 302
                     aa; fasta scores: opt: 561 z-score: 623.2 E(): 3e-27; 47.0%
                     identity in 279 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_625511.1"
                     /transl_table=11
                     /translation="MTESRVQRRRRFVVCEPRHFAVQYAINPWMSTGRPVDVIRALDQW
                     QALVDTYRAHGHTVDTVAPVPGLPDMVFAANCAVVVEGRVFGSLFHAPERRPESVPFEA
                     WFKTEGFEVHHPESVCEGEGDLVPAGRWILAGTGFRTTRAAHREVQEFFGVPVISLTLV
                     DPYFYHLDTALFVLDDGTGGEGRSGGSAGSGGNIAYYPGAFSPGSREVLERLYPDAVIA
                     TREDALAFGLNSVSDGRHVFIAPEARGLADRLAGRGYVPVPVDLSEFHKAGGGIKCCTQ
                     EIRETRS"
     PFAM_domain     35317..35715
                     /aSDomain="DDAH_eukar"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19420.2"
                     /description="N,N dimethylarginine dimethylhydrolase,
                     eukaryotic"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1222_0230"
                     /evalue="4.00E-05"
                     /label="SCO1222"
                     /locus_tag="SCO1222"
                     /protein_end="172"
                     /protein_start="39"
                     /score="23.1"
                     /tool="antismash"
                     /translation="RALDQWQALVDTYRAHGHTVDTVAPVPGLPDMVFAANCAVVVEGR
                     VFGSLFHAPERRPESVPFEAWFKTEGFEVHHPESVCEGEGDLVPAGRWILAGTGFRTTR
                     AAHREVQEFFGVPVISLTLVDPYFYHLDT"
     regulatory      36051..36054
                     /gene_synonym="2SCG58.22"
                     /locus_tag="SCO1222"
                     /regulatory_class="ribosome_binding_site"
     gene            36063..37286
                     /db_xref="GeneID:1096646"
                     /gene_synonym="2SCG58.23; rocD"
                     /locus_tag="SCO1223"
     CDS             36063..37286
                     /NRPS_PKS="Domain: Aminotran_3 (32-352). E-value: 9.1e-102.
                     Score: 332.3. Matches aSDomain:
                     nrpspksdomains_SCO1223_Aminotran_3.1"
                     /codon_start=1
                     /db_xref="GeneID:1096646"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 389.4;
                     E-value: 3.2e-118)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="2SCG58.23; rocD"
                     /locus_tag="SCO1223"
                     /note="2SCG58.23, rocD, ornithine aminotransferase, len:
                     407 aa; highly similar to SW:OAT_BACSU (EMBL:X81802)
                     Bacillus subtilis ornithine aminotransferase (EC 2.6.1.13)
                     RocD, 401 aa; fasta scores: opt: 1356 z-score: 1462.1 E():
                     0; 50.4% identity in 395 aa overlap. Contains Pfam match to
                     entry PF00202 aminotran_3, Aminotransferases class-III
                     pyridoxal-phosphate and match to Prosite entry PS00600
                     Aminotransferases class-III pyridoxal-phosphate attachment
                     site"
                     /product="ornithine aminotransferase"
                     /protein_id="NP_625512.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.9e-115, bitscore:
                     383.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPVRTARGSEELIRAEEPVLAHNYHPLPVVVARAEGAWVEDVE
                     GRRYLDMLAGYSALNFGHRHPALVEAAHRQLDRLTLTSRAFHNDRLAGFAERLAALTGT
                     DMVLPMNTGAEAVESGIKVARKWAYDVKGVPADRATIVVAADNFHGRTTTIVSFSTDET
                     ARSGFGPFTPGFRIVPYNDLAALEAAVDETTAAVLIEPIQGEAGVLIPDDGYLAGVREL
                     TRRKGCLFVADEIQSGLGRTGHTLAVEHESVVPDVVLLGKALGGGIVPVSAVVGRRDVL
                     GVLHPGEHGSTFGGNPLAAAVGTAVVELLETGAFQRRAAELGAVLREGLAALVGRGVVG
                     FRARGLWAGVDVDPALGSGREISERLMREGILVKDTHGSTIRLAPPLTVTAEELTGALG
                     TLEKVLTS"
     aSDomain        36093..37277
                     /aSDomain="TIGR01885"
                     /aSTool="tigrfam"
                     /description="Orn_aminotrans: ornithine--oxo-acid
                     transaminase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO1223_0020"
                     /evalue="4.70E-146"
                     /identifier="TIGR01885"
                     /label="SCO1223"
                     /locus_tag="SCO1223"
                     /protein_end="405"
                     /protein_start="10"
                     /score="484.6"
                     /tool="antismash"
                     /translation="SEELIRAEEPVLAHNYHPLPVVVARAEGAWVEDVEGRRYLDMLAG
                     YSALNFGHRHPALVEAAHRQLDRLTLTSRAFHNDRLAGFAERLAALTGTDMVLPMNTGA
                     EAVESGIKVARKWAYDVKGVPADRATIVVAADNFHGRTTTIVSFSTDETARSGFGPFTP
                     GFRIVPYNDLAALEAAVDETTAAVLIEPIQGEAGVLIPDDGYLAGVRELTRRKGCLFVA
                     DEIQSGLGRTGHTLAVEHESVVPDVVLLGKALGGGIVPVSAVVGRRDVLGVLHPGEHGS
                     TFGGNPLAAAVGTAVVELLETGAFQRRAAELGAVLREGLAALVGRGVVGFRARGLWAGV
                     DVDPALGSGREISERLMREGILVKDTHGSTIRLAPPLTVTAEELTGALGTLEKVL"
     PFAM_domain     36126..37277
                     /aSDomain="Aminotran_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00202.24"
                     /db_xref="GO:0008483"
                     /db_xref="GO:0030170"
                     /description="Aminotransferase class-III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1223_0231"
                     /evalue="1.20E-114"
                     /gene_ontologies="GO:0008483: transaminase activity"
                     /gene_ontologies="GO:0030170: pyridoxal phosphate binding"
                     /label="SCO1223"
                     /locus_tag="SCO1223"
                     /protein_end="405"
                     /protein_start="21"
                     /score="383.3"
                     /tool="antismash"
                     /translation="LAHNYHPLPVVVARAEGAWVEDVEGRRYLDMLAGYSALNFGHRHP
                     ALVEAAHRQLDRLTLTSRAFHNDRLAGFAERLAALTGTDMVLPMNTGAEAVESGIKVAR
                     KWAYDVKGVPADRATIVVAADNFHGRTTTIVSFSTDETARSGFGPFTPGFRIVPYNDLA
                     ALEAAVDETTAAVLIEPIQGEAGVLIPDDGYLAGVRELTRRKGCLFVADEIQSGLGRTG
                     HTLAVEHESVVPDVVLLGKALGGGIVPVSAVVGRRDVLGVLHPGEHGSTFGGNPLAAAV
                     GTAVVELLETGAFQRRAAELGAVLREGLAALVGRGVVGFRARGLWAGVDVDPALGSGRE
                     ISERLMREGILVKDTHGSTIRLAPPLTVTAEELTGALGTLEKVL"
     aSDomain        36159..37118
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO1223_Aminotran_3.1"
                     /evalue="9.10E-102"
                     /label="SCO1223_Aminotran_3.1"
                     /locus_tag="SCO1223"
                     /protein_end="352"
                     /protein_start="32"
                     /score="332.3"
                     /tool="antismash"
                     /translation="VARAEGAWVEDVEGRRYLDMLAGYSALNFGHRHPALVEAAHRQLD
                     RLTLTSRAFHNDRLAGFAERLAALTGTDMVLPMNTGAEAVESGIKVARKWAYDVKGVPA
                     DRATIVVAADNFHGRTTTIVSFSTDETARSGFGPFTPGFRIVPYNDLAALEAAVDETTA
                     AVLIEPIQGEAGVLIPDDGYLAGVRELTRRKGCLFVADEIQSGLGRTGHTLAVEHESVV
                     PDVVLLGKALGGGIVPVSAVVGRRDVLGVLHPGEHGSTFGGNPLAAAVGTAVVELLETG
                     AFQRRAAELGAVLREGLAALVGRGVVGFRARGLWAGVDV"
     misc_feature    36174..37223
                     /gene_synonym="2SCG58.23; rocD"
                     /locus_tag="SCO1223"
                     /note="Pfam match to entry PF00202 aminotran_3,
                     Aminotransferases class-III pyridoxal-phosphate, score
                     426.50, E-value 8.5e-148"
     misc_feature    36750..36863
                     /gene_synonym="2SCG58.23; rocD"
                     /locus_tag="SCO1223"
                     /note="PS00600 Aminotransferases class-III
                     pyridoxal-phosphate attachment site"
     gene            complement(37302..37760)
                     /db_xref="GeneID:1096647"
                     /gene_synonym="2SCG58.24c"
                     /locus_tag="SCO1224"
     CDS             complement(37302..37760)
                     /codon_start=1
                     /db_xref="GeneID:1096647"
                     /gene_synonym="2SCG58.24c"
                     /locus_tag="SCO1224"
                     /note="2SCG58.24c, possible sugar-phosphate isomerase, len:
                     152 aa; similar to SW:RPIB_ECOLI (EMBL:X82203) Escherichia
                     coli ribose 5-phosphate isomerase B (EC 5.3.1.6) RpiB, 149
                     aa; fasta scores: opt: 248 z-score: 314.7 E(): 4.6e-10;
                     36.6% identity in 134 aa overlap"
                     /product="sugar-phosphate isomerase"
                     /protein_id="NP_625513.1"
                     /transl_table=11
                     /translation="MRISVSSDMDEPVARLLVEELRARGHEVRAYGALSPGADPRWAAC
                     SERAAREVAEGRADQAVVCCWTGTGASIAANKVPGVRAALCADAYTADGARRWNDANVL
                     AIGLRLTSAPLLREILDAWFAGGPSTDAEDRDNVAHVERLDEDRRAAR"
     PFAM_domain     complement(37326..37718)
                     /aSDomain="LacAB_rpiB"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02502.21"
                     /db_xref="GO:0005975"
                     /db_xref="GO:0016853"
                     /description="Ribose/Galactose Isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1224_0232"
                     /evalue="5.60E-31"
                     /gene_ontologies="GO:0005975: carbohydrate metabolic
                     process"
                     /gene_ontologies="GO:0016853: isomerase activity"
                     /label="SCO1224"
                     /locus_tag="SCO1224"
                     /protein_end="145"
                     /protein_start="14"
                     /score="107.6"
                     /tool="antismash"
                     /translation="RLLVEELRARGHEVRAYGALSPGADPRWAACSERAAREVAEGRAD
                     QAVVCCWTGTGASIAANKVPGVRAALCADAYTADGARRWNDANVLAIGLRLTSAPLLRE
                     ILDAWFAGGPSTDAEDRDNVAHVERLD"
     regulatory      37889..37892
                     /regulatory_class="ribosome_binding_site"
     gene            37902..39416
                     /db_xref="GeneID:1096648"
                     /gene_synonym="2SCG58.25"
                     /locus_tag="SCO1225"
     CDS             37902..39416
                     /codon_start=1
                     /db_xref="GeneID:1096648"
                     /gene_functions="transport (smcogs) SMCOG1074:major
                     facilitator family transporter (Score: 462; E-value:
                     3.1e-140)"
                     /gene_kind="transport"
                     /gene_synonym="2SCG58.25"
                     /locus_tag="SCO1225"
                     /note="2SCG58.25, probable osmoprotectant transporter, len:
                     504 aa; similar to SW:PROP_ECOLI (EMBL:M83089) Escherichia
                     coli proline/betaine transporter ProP, 500 aa; fasta
                     scores: opt: 1534 z-score: 1728.8 E(): 0; 44.7% identity in
                     465 aa overlap. Contains Pfam match to entry PF00083
                     sugar_tr, Sugar (and other) transporter and matches to
                     Prosite entries PS00217 Sugar transport proteins signature
                     2 and PS00216 Sugar transport proteins signature 1. Also
                     contains possible hydrophobic membrane spanning regions"
                     /product="osmoprotectant transporter"
                     /protein_id="NP_625514.1"
                     /transl_table=11
                     /translation="MEREAATSPTENGPETDAAAVRRHPALFRAIKRRQNPRLRRSDIT
                     VTDEAAVKRAVKAASLGNAMEWFDFGIYAYLAGTIGRVFFPSGSDTAQLLSSFATFAVA
                     FLVRPIGGMVFGPMGDKIGRKKVLALTMILMAIGTAAIGFIPSYDSIGFWSPLLLILFR
                     LLQGFSTGGEYGGASTFIAEYAPDKRRGFFGSFLELGTLAGYTAAASLVTALTAVLGSD
                     GMDSWGWRVPFLAALPLGMIGIYLRLRLDDTPAYLKLEDSNVHVSEAATAVETTARGDL
                     AKIFRTHWRALVLCIALVGAYNITDYMLLSYMPTYLSDELDYSESHGLMILVATMVLLM
                     LIINQVGRLSDRFGRKPVLMTGMIGFFVLSAPAFVLVQEGSLLAVSGGMLMLGLSLVCL
                     LGTMSAALPAMFPTNVRYGSLSVGYNLSASLFGGTTPLVITALISVTGSDMMPAYYAMA
                     AALIGVVAVACMKETAQQPLAGSPPSVQTEEEAAEMVEAQAPTPKF"
     misc_feature    38061..39356
                     /gene_synonym="2SCG58.25"
                     /locus_tag="SCO1225"
                     /note="Pfam match to entry PF00083 sugar_tr, Sugar (and
                     other) transporter, score 195.80, E-value 6.8e-55"
     PFAM_domain     38076..39335
                     /aSDomain="Sugar_tr"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00083.27"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Sugar (and other) transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO1225_0233"
                     /evalue="9.80E-45"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="SCO1225"
                     /locus_tag="SCO1225"
                     /protein_end="478"
                     /protein_start="58"
                     /score="153.4"
                     /tool="antismash"
                     /translation="ASLGNAMEWFDFGIYAYLAGTIGRVFFPSGSDTAQLLSSFATFAV
                     AFLVRPIGGMVFGPMGDKIGRKKVLALTMILMAIGTAAIGFIPSYDSIGFWSPLLLILF
                     RLLQGFSTGGEYGGASTFIAEYAPDKRRGFFGSFLELGTLAGYTAAASLVTALTAVLGS
                     DGMDSWGWRVPFLAALPLGMIGIYLRLRLDDTPAYLKLEDSNVHVSEAATAVETTARGD
                     LAKIFRTHWRALVLCIALVGAYNITDYMLLSYMPTYLSDELDYSESHGLMILVATMVLL
                     MLIINQVGRLSDRFGRKPVLMTGMIGFFVLSAPAFVLVQEGSLLAVSGGMLMLGLSLVC
                     LLGTMSAALPAMFPTNVRYGSLSVGYNLSASLFGGTTPLVITALISVTGSDMMPAYYAM
                     AAALIGVVAVACMKETAQQPL"
     misc_feature    38394..38471
                     /gene_synonym="2SCG58.25"
                     /locus_tag="SCO1225"
                     /note="PS00217 Sugar transport proteins signature 2"
     misc_feature    38937..38987
                     /gene_synonym="2SCG58.25"
                     /locus_tag="SCO1225"
                     /note="PS00216 Sugar transport proteins signature 1"
     stem_loop       39433..39485
                     /note="possible stem loop. Score 75: 25/25 (100%) matches,
                     0 gaps"
ORIGIN
        1 cgtggtcgcc cggctcacgc cggccccgca gccccgcgcg tcgctgctgg cggcgagcca
       61 tcccaccgat ccggacagcc ggatcgacct cggtctcgac cggctccgcc gcgcggacct
      121 gcccgcggaa gcggcgtcgg gccccgcggg cgacgcgccg acgaccccgt ccgtacgggc
      181 ggcgaccgcc gcggacgagg ctcccgtgca tctgctgcgg cgccgggtcc accaggccgc
      241 gtccggtggc cgccgcgtac tggccttccc cggaaaccgt gagtccgagg ccgcgcgcct
      301 gcgtcggtac ggcctcggca ccgccggtga gctgctcgcc gagttgcacg ccaccgccgc
      361 ggaacgggcg cgcgacccct tcggccggct gctcccggcc gacaccgggc gcttcgcccg
      421 cgcgtggctg ggcgcggccg tctacaccga ggaggtggac cgtgccctgt gtgccgccgc
      481 gtggggcgcg aggctccccg gcctcacctc tccgtgatcc gccgtcccgg cgcgcaggcg
      541 gcccggcggg tcaccgtagt atcggacgat ctcgtggggg aaggcgggcg gacatgggca
      601 ggcagcgtcc gggtacgccg acgctggagg aggtggccgc ccgcgcaggc gtggggcgag
      661 gcaccgtctc aagggtcgtc aacaacgcgg ccggcgtgcg cgactcgacg cgccgcgccg
      721 tgcagcgggc catcgccgag ctgggctacg tgccgaatct cgcggcccgt tcgctcgccg
      781 gccaccgtgc ggacgccgtc gcgctggtga tgacggagcc ggactggcgg ttgttcgggg
      841 agccgttctt cacggagatc gtccacgccg tcggcgacgc cctcaccgac accccgttcc
      901 agctgctgct caccctggtc cgcacggaca ccgagcggcg gcgtttcgtg gagtacgcgc
      961 gcggcggccg ggtcgacggg gtgctgctca tgtccgtgca cgccgaggat ccgctgcccg
     1021 acatgctcgc cgacgcggga ctgcccaccg tcatgctggg gcggcgttcc ggcgaggagt
     1081 gcgtcaccta cgtcgacgcg gacaacgcgg gcggtgcgcg cggcgcggtg acgtatctgc
     1141 tggacgccgg ccggcgcagg atcggggcca tcagcggtcc gctcgacatg tacgtcgccc
     1201 agtgccgact gcgcggctac cgggaggcgc tggagccggc gggcgtggct gcgggggcgt
     1261 cgctggtcgt cgaggggagc gacttcaccg aggagagcgg gcaccgggcg atgaccgagc
     1321 tgctggcccg gcacccggac ctggacgcgg tcttcgccgc ctcggacacg ctggccgccg
     1381 gggcgctcaa cgcgctgcgc gccgcgggcc gacgggtgcc gcaggacgtc gccgtgatcg
     1441 gcttcgacga cttccacccg gcccggccca cggacccgcc gctgacgacc gtccggcagc
     1501 cgctggagga gatcggccgc acgatggtgc ggctgctgct ggaggagatg gaggacgccc
     1561 cggtcgcctg gcggcacgtc atcctccgta ccgagctggt agtccgggac tccgcctgag
     1621 caaccgggcc gccgggagcg ctcccggagc gggacccctc cgacctgcgg cttcgagatt
     1681 cgttcgacaa ctctgccgcg cacagtcttg tcaggaacat gaaccgcttc tacagtccca
     1741 tcaaccggca agtgggagcg ctcccatcag tggggagttg ggagcgctcc cgcaccggcc
     1801 ccctccctcc ccccacaccc tcccggagag gcccccatgc gaacgttacg gccccaggcc
     1861 cgcgccccgc gcggcctctt ggcggccctg ggcgcggtct tagcggcctt cgccctcgtg
     1921 tcgtccctgg tgacagccgc cgcgcccgcc caggcggaca ccacgatctg cgaacccttc
     1981 ggaacgacga cgatccaggg caggtacgtc gtccagaaca accgctgggg ctccaccgcc
     2041 acccagtgcg tcacggccac cgacaccggc ttccgggtca cgcaggccga cggctcggca
     2101 ccgaccaacg gggcgccgaa gtcgtacccg tcggtcttca acggctgcca ctacacgaac
     2161 tgttcaccgg gcacggccct ccccgtccgg ctcgacaccg tctccgcggc gccgtccagc
     2221 atctcgtacg gcttcgtcga cggcgccgtc tacaacgcct cgtacgacat atggctggac
     2281 ccgacggccc gcaccgacgg ggtgaaccag accgagatca tgatctggtt caacagggtg
     2341 ggtccgatcc agcccatcgg ctcaccggtg ggcacggcct ccgtcggcgg ccggacctgg
     2401 gaggtgtgga gcggcggcaa cggctcgaac gacgtgctgt cgttcgtggc accgtcggcg
     2461 atcagcggct ggagcttcga cgtcatggac ttcgtccggg cgaccgtcgc gcgcggactc
     2521 gccgagaacg actggtacct gacgagcgtt caggcggggt tcgagccgtg gcagaacggc
     2581 gccggactgg ccgtgaactc cttctcctcc accgtcgaga ccggcacccc cggcggcacc
     2641 gaccccggcg acccgggcgg cccgtccgcg tgtgcggtgt cgtacggcac gaacgtctgg
     2701 caggacggct tcaccgcgga cgtcaccgtc accaacacgg gcacggctcc cgtcgacggc
     2761 tggcaactcg ccttcaccct gccctccggc cagcggatca ccaacgcctg gaacgcgtcc
     2821 ctgacgccct cctcgggctc cgtcacggca accggcgcga gccacaacgc ccggatcgca
     2881 ccgggcggca gcctgtcatt cggcttccag ggcacctacg gcggcgcgtt cgccgagccg
     2941 accggcttcc gcctgaacgg caccgcctgc accacggtgt aaccgccccg cctccccgcc
     3001 cgtccggtcg aagcgcccgc cccggacggg cgggggttcc acgggacgcc cccaccattg
     3061 tcatgaactg atcatccagc cgctcaggca ctcattcaga cacccgctca gacacccgtc
     3121 ccgacccgct cagacacccg ctcagacatc ccgacccgct cagacacccg ctcagacact
     3181 cattcagacg cttgtcagcc cactcacgca ccggaaccag gaggccccta tggttcgacg
     3241 caccagactc ctcaccctcg cggcggtact ggccaccctg ctcggctcgc tcggcgtgac
     3301 ccttctgctc gggcaggggc gggccgaggc gcacggcgtg gcgatgatgc ccggctcccg
     3361 cacctacctg tgccagctgg acgccaagac cggcaccggc gccctcgacc cgacgaaccc
     3421 cgcctgccag gccgccctcg accagagcgg ggcgacggcc ctgtacaact ggttcgccgt
     3481 gctcgactcc aacgcggggg gccgcggcgc cggttacgtg ccggacggca ccctgtgcag
     3541 cgccggcgac cgttccccgt acgacttctc cgcctacaac gccgcccgct cggactggcc
     3601 ccgcacgcac ctgacgtcgg gtgcgacgat cccggtggaa tacagcaact gggcggccca
     3661 ccccggggac ttccgggtgt acctgaccaa gccgggctgg tcgcccacgt ccgagctggg
     3721 ctgggacgac ctggagctga tccagacggt gaccaacccg ccccagcagg gctcgccggg
     3781 caccgacggg ggccactact actgggacct cgcgctgccc tcgggccgct cgggcgacgc
     3841 gttgatcttc atgcagtggg tgcgttcgga cagccaggag aacttcttct cctgctcgga
     3901 cgtcgtcttc gacggcggca acggagaggt caccggcatc cgcggttccg ggagcacccc
     3961 ggacccggac ccgacaccga ccccgacgga cccgaccacc ccgcccacgc acaccggctc
     4021 ctgcatggcc gtgtactcgg tggagaactc ctggagcggc ggcttccagg ggtcggtcga
     4081 ggtgatgaac cacggcaccg agccgctgaa cggctgggcc gtgcagtggc agccgggcgg
     4141 cgggaccacg ctcggcgggg tgtggaacgg ttcgctgacc agcggctccg acggtacggt
     4201 cacggtccgc aacgtggacc acaaccgcgt cgtaccaccg gacgggagcg tgaccttcgg
     4261 cttcaccgcc acttcgacgg gcaatgactt cccggtcgac tcgatcggct gcgtggcacc
     4321 ctgacgcaca cctcgtagca cgccccggcg cacgccacga cgcacgccgg gaatggcgtc
     4381 gggacacgcg tcggcacacg gtcggcgggg gcaccagggc tcccgccgac ctcacgtgcc
     4441 ggttacaaat cgctcaacct ctggttgcga agcggtgagc gggcgacgat agggccatga
     4501 ctccggccca gcgcgccttc gagcggctgc aagcctggcc cgacctctcg gcgggtccgg
     4561 ccagttgcgg aaccggacgg gcactgtgct ccgtccgcga cgagatcgtc cacttccact
     4621 cggaccggga cgtggacctc cacctcaccc accgggccat ccagcgcttc cggtacgacc
     4681 tgggcggctc caccgccatc cgtctggtgc ccggctcccg ctgggtcacc gtgcacctgg
     4741 actgcgacgc ggacgtggat ctgctgttga gcctggtgag catcgccctg aaggcccatc
     4801 agtcccggcc cccggccgac ctcgccccgg ggccaccggg gccgacggcg ctgtcggcgc
     4861 cgccggggtg caacttccac cgggtcacgg tgcttccgcg tgccgcggcc ggggaggcct
     4921 gagtccggcc gccgcgaggg cagcaccgaa cacgcagagg gcaccggtga cgaccacggc
     4981 cacgtgcacg ccgttcatga acgcctgccc gctgccctcc accacggctg cccgcagccc
     5041 ggccggcatc tcgccggaga cgggcgccac gcccatggcc acggcgtccc gggcctcctg
     5101 gagaccgtgg gccacggccg ggggcacgcc cgcgccggtc agctcaccgg tgagggtggc
     5161 gtccaccttg gcgctgatca gggagaccag cacggacgtg ccgagcgcgc cgccgatctg
     5221 cagggtcgtc gcctggagac cgcccgccac cccgccgtcc cggacggggg cgttgcccac
     5281 gatggcgtcg gaggaggcgg ccatcaccat gccgacgccg aggccgagcg cgatgaacgg
     5341 cggccacatc gtggcgtagg cggagtcggt ctgccaggtg agcatgccga agcaggaggc
     5401 ggcctggagc agcatgccca gcggcatggt cagccgcggc ccgaagcgct gggtcagggc
     5461 cgcgcccagc ggcgaggcga ccagcgaggc gaggctgagc gggagcgtgc gcacgcccgc
     5521 ctcgaccggc gtgaagccgc gcacgttctg caggtagagc atgacgaaga agatcacgcc
     5581 tagcatcacg aagaagttca gcgcggtgac gatcgcgccg atggtcagcg cgcggctgcg
     5641 gaacaggcgc atcggcagca gcgggtgctc cacgcgggtc tcgtaccggc cgaacacgag
     5701 gaggagcagg agaccggcgg ccacggcacc gagggtgccg gcggaggtcc agccccaggt
     5761 ctcgcccttg acgacgccga agacgactgc caggaggccg agggcgagca ggacgagccc
     5821 gggtatgtcg aagcgctcgc ggcccgcggc gttgcggctc tgcgggagga cgagggcgcc
     5881 gaaggcgatg gcggcgacgc cgatgggggc gttgacgtag aagacggact cccagtcgac
     5941 gtgctccacg aggaggccgc cgacgatggg cccgagggcc gtggcgacgg cggagaccat
     6001 ggcccagatg ccgacggcca tgccgaactt cttcggcggg aagacggagc ggagcagccc
     6061 gagggtgttg ggcatcagca gtccgccgaa ggcgccttgg agggcgcgga aggcgacgac
     6121 gccctcgatc gaaccggcca gtccgatggc gatcgaggcg agggtgaagc cggcgacgcc
     6181 caccaggtag taggtgcggc ggccgaagcg gtcacccagc ttgccgccca ggatgagggt
     6241 ggcggcgagg gccagcaggt aggcgttggt cacccactgg agctgggcgg tggacgcgtg
     6301 caggtcgctg ccgatctcgg ggttggcgat ggcgacgacg gaaccgtcga gctggaccat
     6361 gaacaggccg aacgcgacgg cgaggagggt cagccacggg ttggaccgca gccggccggc
     6421 ggccccgggc gcgggggcgg gctcggccgc gggcacggcg gggtgatcca cggacgtgga
     6481 gggcatggag gagcttctct tccggtttca ggggtggtgc gggaagggag cggcgcgccg
     6541 cgagggcggg cgcacgggtc agcggacgcc ggggtggagg tgccgcgtca acgcgtcgag
     6601 ggcgtccagg gcggagccga gcgcgccctg ctggccctcg gtgagggagg tcagggcgtg
     6661 gcggatgaac gcggtctcca gttcccgcac ctcggagacc cgctcacgag ccgtggccgt
     6721 gaggtggagg tgggcgaccc gcttgtcggc gctgtcccgc cggcgctcca ggtcaccctg
     6781 ctcgacgagc tgggagacca gggcactgac gttgttcggc ttcatcagca gggcctcggc
     6841 ggcctcgcgc accgtgacgc cctcgtgctg cgcgacgtac cgcagcaggg cgagctgccc
     6901 ctcggggggc ttggggtgcg ggtaccgggc cgtgacctgc cggtccagcg cccggtgcag
     6961 cacgggaagg cacgccgcga gcccggaggc catgcggtcg atgtcccggc gaggggtgct
     7021 ggagtcggtc acccggagac aatagatagg gtcggatagg tatgtcaaaa gaggtttctg
     7081 gcggaggagg cgggatcgcc ccgccaaggt gccgcgcaac gcgctcgcaa cgttccccgt
     7141 gctggcatgt gcggcatggg cgacacatac gaggagaccc cgcgcgtcga gctgaccccc
     7201 gaggcgtccc tactgctgcg gcggctccgc gaggcgcacg gcccgctgat gttccatcag
     7261 tccggcggtt gctgcgacgg cagcgcaccc atgtgctatc tggccggcga gttccgcacc
     7321 ggcgcctcgg acatcctgct cggcgagctg gccgtcgacg gcgtcgagga accggtggag
     7381 ttctggatgt cacgcagcca gtacgaggcg tggcgccaca cccggctgat cgtcgacgtg
     7441 gtcccgggcc ggggcagcgg cttctccctg gaggcacccg agggagtgcg cttcctcatc
     7501 cgctcccgcg tcgtggacgt ctagaaccct gtcttccttc ggccgtcagc tcaccagggg
     7561 caggaagatc gtgtcgacga tctcctcgac gacgtcctcg gggaccggcg cgagggtcgc
     7621 gaggatctcc tggcgcagca ggtcgaaggg gagggacctg acgcgcccgg tgagccgttc
     7681 cggcctggcc tcgccgcggg cgacggcccg gtcgtagacc tcggcgagcg cgtccgcgga
     7741 cttcccgcgc gccgcgtcga gcagctcgcc ggggctggtg ccggtctcct ggcagtagcc
     7801 ggccaggtgc gcgtacatga ggatgacgag ctgggcgttg gcggtgccga tctcccgcat
     7861 gagggcgagg aggtcccccc gcagggttcc cgtgtcgggg gtgtcgacgc gggcttcctc
     7921 cagcacatgg gcgacggctg ccctggccag ctcgtcgcgg tgcgcccagc gccggtacag
     7981 caccggcggg ctggtgccgg cgcgcctgac gacgccgtcc atggtgaacc gggcgtagcc
     8041 gcgctcggcg agttcgcccc aggccgcgtc caggagtgcc ttctccagtg ccgctccgcg
     8101 gcgccgctgt gccatccgac gcctccttcc agtgagaaag aattgccttt cttatcctat
     8161 ctccctactc tgaggagagt aagaaaggac tccctatctt aaggaggtgg gggttcgtga
     8221 gcatccccca tggggccgcg tccgcggcag cacgtcccga tcgcgtcgac cccgccgtcc
     8281 ggcgcattgg ggccaccctc gtcgtgggcg cgctcggagt cgtcttcgac accaccgtcg
     8341 tcagcgtcgc gctggacgac ctggcgaagg cgttcgacgc cccgctggcc acggtccagt
     8401 gggtgagcac cggctacctg ctggcggtgt tcgtcaccat cccgctcgcc gtgtgggccc
     8461 aggcgcgctt cggcggccga cggctgtgga tcgcggcgct gggcggtttc ctgctcggct
     8521 cggtcctgag cgcgctggcg tggaacgcca cgagtctgat cgtcttccgt gtcgtccagg
     8581 gcctcgcggg cggcatcatg atgccgctca tggccacgct gctcatgcag gcggccaggg
     8641 gcagccaccc gggcagggtc atggcgatca tcacggtgcc caccgcgctg ggcccgatcc
     8701 tgggcccggt cctcggcggc ctcgtcctgc atctggccga ctggcgctgg atgttcttcg
     8761 tcaacatccc gttctgcgtc gtcggcggat ggctggccct gcggaacctc cccgacgacc
     8821 ggccggagcc cggcggcccc cgcggccgcc tggacgtcgt cggcctgctc ctgctctgcc
     8881 cgggcgtcgc cgccctggtc tacggcctgt cccgggtcga gggcggagcc ggaaccaccg
     8941 gcgccgcggt cctcgtgccg ctgctcggcg gactcgccct ggtcggcggc ttcacggccc
     9001 ggtccctgac ccgtcccggc ggtgccctga tcgatctgcg gctgttccgc caccgcgcgg
     9061 tggcctcctc cgccgccctg ctcttcctgg gcggcatcgc cctgtacggg ccgatgatgc
     9121 tgctgcccct gtacttccag caggtccgcg gcgaggacgc cctcggcgcc gggctcgcgc
     9181 tcatcccgca gggtgtgggg gcgctgctcg cacgcgccct ggcgggcagg tacatggacc
     9241 gcgtcggccc ccgccgggtc gccgtcaccg cgttcgccct cgtcgccgtg gccacggtcc
     9301 cgttcgcctt cgtcaccgcc ggcaccggcg gggccgtgct catggccgcg ctgttcgtcc
     9361 gcggcatcgc gctcggcgcc gccatgatcg cgccgatggg cgccgcctac gtcgggctgc
     9421 ggcaccagga gatcccggac gcgggtgtca tcacccgcgt cgcccagcag atcggcggct
     9481 ccgtgggcat cgccctgctc gccgtcgtcc tgcagcacgc cgctgccggc gcccacggcc
     9541 cgagcgccct ggccggcgcc ttcgaccggg ccttctggtg gtcggcggtc ctcaccgctc
     9601 tcgccgtccc gctgtgcctg ctgctgcccg gccgaccgga gcccccgccc cccgcccgga
     9661 ccacgcggac cggcgaggcc gtcgaccccc gccgtcctac ggtctgaggc tgcccacgat
     9721 gtccgccgtg gcggtcagtc cgctgttgat ggtcggggcg atgctcgtgc tcgccaggta
     9781 gaagccgagc agcaggcaca ccagggcgtg cgagaccttc agcccgccgt tgcgcaggaa
     9841 gagcaccgcc aggatggaca gcaagagcac cacagagatg gaaacggcca tcgtcaacct
     9901 cctccgccac gtccacttcg cggcgttcgg ccgtaagtgt ggcgtagcgg agggttcgtc
     9961 cgggcggctg acctgtcctc cgaacgagtg gtgttgagac gcttcctacg cgtcccggtg
    10021 cgcgtcgagg aacgcttcga tgcccgcgag gtcgtcggtg ttgaggtggt cgacaccggc
    10081 ggcgagcagt tcggcccaca cggcgtcccg cgccggaccc gccacatcgg gcgtggccca
    10141 gaagcgcacc cgctgcccgc gcgcgtgtgc cgcgcccacg atgtcccgca gcctgcgccg
    10201 ctcggcggcc gggaaggtgc cgacgccctg ccaggtgaag ttgagcgtcc agttgtcgct
    10261 gatcagcggg acgaacgagg ccggtgccac ggtgccgagg tcggtgaggc ggccgtcgta
    10321 gaaggcacgg cggctgcgct gggccgccat cggcgcacgg gccgcccgat ctccggagac
    10381 gacggccgta acggcgcccg ggaagacccg cccgtgggcg taggaggtga acaggttctt
    10441 gtagcggcgc agtcggcggt cgagttcgag gtaggtcgcc tcaccctcgg tcttgatgtc
    10501 gatcaggagt tgcagggagc cgcggtcccg tcggtagacc cggccgtggt gcgcgcggac
    10561 gcgggcggcg agcgggtcga ggtagagcga ctccagggtg cgggacgggt cgaggtcctc
    10621 ggggtcgtgg gcgaccagga gttggccgcc gaccaggtag atgtcggctt cgacgctgcc
    10681 gaagcggtgg tcgagggcgt cgaggagggg ccgggggtgc tcgtagtcgt tgtgggcgtg
    10741 cgcacgccac agcgggcgcg gtccgtgccc gccctgggac gccagcgcgg taccggcggg
    10801 cagggcgacc gcgcccgtga gggcggcgcc gagagtggtg agggctctgc gtcgggtggt
    10861 gagggccatg ctctgcctcc ctggaagtgc cgtacgggac gcctgtgagt atggggtccc
    10921 gacggccccg gggagcagag ccgtgcggtg agttggccgg accgccgccg gtcgttcact
    10981 tcggtcgttc acctcaccgg agcgggccac cgggcgcact cgcgcgcggg cgggtgcgtc
    11041 agggggcccg caggtcgacc agttcggcca gcgccgcgcg gtgggtgccc ggcgctccgt
    11101 aggcgatcga gtcggccttg gcccgcttga ggtacaggtg gaccgggtgt tcccaggtca
    11161 tgccgatgcc gccgtgcagt tgcagcgcct cctcggcggc gtgcacggcg acctgggccg
    11221 cgtacgcctg ggccacggcg acggccacgt cggtgtccgc gccggtcgcc agggcgtcgg
    11281 ccgcgttccg ggccgcggcg cgcaggccgg ccacctccag ccacagccgg gacagccggt
    11341 gcttgagcgc ctggaagccg ccgacctggc ggttgaactg cttgcgttcc ttgaggtggc
    11401 ggaccgtctc ggtcagcaac cagtcggcga ggcccagctg ttcggcggcg agcagcccgg
    11461 caccggcccg cagggcacgg cgtacggccg gttccgcgtc accgaggcga cgccccgggg
    11521 cgccgtcgag ggtcacgcgc gccagcggcc gggtggagtc gagcgacacc tgcccggtga
    11581 ccgcggcgtc cgcggcggcg accgcgtaca ggcccccgtc gtccgcgggc acgagcagca
    11641 cgtcggcgac ggacgcgtcg gcgatgccgg tcagctcccc gtgcagcgcg cccccttcga
    11701 gccgcacccg cggggcggcg ccgcccggtg cgacgtgcag gccgacggcg agcacggcga
    11761 cggtggtggc ggacgccagc tcgccgagca ggtcgtccgc cccgcaggca agcagcgcct
    11821 cggtggcgac gacggcgctc gtcaggtacg gcaccggtgc gaccgcgcgg cccagttcct
    11881 ccaggaccac ggcggcttcg cggtgggtgg cgccctgccc gcccagttcc tccgggatca
    11941 gcaggccggc gaggcccatc gagccggcga gggccttcca cagcgacacg tcgtggcggg
    12001 cggccgactc ggtgcgggtg atgacgcccg ccgggtcgca gtggtcggtg agcaggtccc
    12061 ggacggcggc gcgcagcgcc tcttcctcct ccgagaggag cagggcgggt tccggctgtg
    12121 cgctcatcgg gcgaggtcct tccatgcgac gtccttgtcg gtgcgcggct cggcgggcag
    12181 gccgaggacg cgctcggcga cgatgttcag caggacctcg ctggtcccgc cctcgatgct
    12241 gttgcccttg gaccgcaggt agcggtatcc ggcgtcgcgg ccggtgaagt cgaccagttc
    12301 ggggcggcgc atggtccagt cgtcgtagag caggccctcc gcgccgagga gttccacctc
    12361 cagaccgctg atctcctggt tgagccgggc gaagttcagc ttcatgccgg cgccctcggg
    12421 gccgggctgc ccggccgcca gttgctggcg caggcgtaca ccggtgaggc gggcgacctc
    12481 ggcctcgacc cacaggccga gcagccgctg gtgcaggtcg tgggtgcgca gttcggggcg
    12541 ttcccgccag gtctcggcga tcttgccgat catgccgccc tcgcggggga tcggcgtgcc
    12601 gccgatggcg acgcgttcgt tgttcagcgt ggtctgcgcg acccgccagc cgtcgccgac
    12661 ctcgccgagc cggcgggagt cggggatgcg gacgtcggtg aggaacacct cgttgaactc
    12721 ggcctcgccg gtgatctggc gcagcggccg cacctcgacg ccggggtcgg tcatgtcgca
    12781 cacgaagtag gtgatgccct ggtgcttggg cacgtccggg tcggtgcggg cgatgaggat
    12841 ggcccagcgg gcgaggtgcg cgctggaggt ccacaccttc tgcccgttga cgacccagtc
    12901 ctcgccgtcc cgtaccgcgc gcgtgccgag agcggccagg tcggatccgg cgcccggctc
    12961 gctgaagagc tggcaccaga cctcctcgcc ggtccacagc gggcgcagca gtcggcgctt
    13021 ctgctcctcg gtgccgtact ggaggatggt cggggcggcc atgccgaggc cgatgccgat
    13081 gcggcggggg tcgttgtcgg gggcgcccgc ggccgccagc tcggcgtcca cgacggcctg
    13141 gagggcgcgt ggggcaccga ggccgccgag cccctgcggg tagtgcaccc aggccagtcc
    13201 ggcgtcgaag cgggcccgga ggaagtccag gcggtccgtg tcggccggtg ggtgcgcggc
    13261 gagcaactcg cgcgtacggt cgcgcagttc cgctgcgtcg gtcatgcggc ggctcccttg
    13321 tccaggttct ccggtacgac ggccaggcgg ccggtcgtcc tgccgtcggc gacgcgctgc
    13381 acggcgtcgg cggcgtcggc gagcggcacc cgctcgctca ccagcggctt gatcgcgccc
    13441 cgcgccgcca gctcggtgag ctgctcgtgg cagtgccgga ccagcttcgg gtccttggtg
    13501 ttgtacaggc cccagtgcag gccgaggatc gcgtagttct tcaccagcgc gtggttgagt
    13561 gccgggctgg ggatcgtgcc gctggcgaag ccgacgacga cgatccggcc ctcgaaggcg
    13621 acgaccttgg cggactgggc gtaggcctgg ccgcccacgg ggtcgtagat cacgtcggcg
    13681 ccccggccgc cggtggcctc cttcacggcc gcgacgacgt cctcggcatg ccggtcgacg
    13741 accacgtcgc agcccagctc gcgggcgacg gccgccttct gcgagccgcc gacgacgccg
    13801 atcacggtgg cgccggccgc cttgccgagc tgcacggcgg cgctgccgac gccgcccgcc
    13861 gcggcgtgga cgagcagggt ctcgccggct tccagccggg cccggcggtg caggccgaac
    13921 cagccggtct ggtagccgat gtgcagagcg gccgcctcgg cgtcgtccag ggagtccggc
    13981 gcgggcagca gggcccgggc gtcggcgagg gcgtactcgg cgaagccgcc gtgcggcagc
    14041 gcggggttgg cgatgacgcg gcgcccctcc tcggtctcgc cgcagatctc cacgcccggc
    14101 gtgaacggca gcggcggccg gacctggtac tgcccgcggc acatcagggc gtccgggaag
    14161 ttgatgttcg cggcgcggac cctcagcagg acctgaccct cgccgggcgt cggcggcgcc
    14221 acgtccgcga ggcgcatcac ctcgcccggc tcgccgttct cgtgcacctg ccatgcctgc
    14281 atgcggggcc tccaccgact gcgtcgtccg accgggtcct ccgcatacta agcggtcgct
    14341 tgccgatcag ggaacagggt gcggggtcac gcctgcgcgg gccgcgcccg tacgtgcatc
    14401 cgctccccct gcgggccgaa gaggctgagg aactcggccg gcccctcccc cgtcgacccg
    14461 aaccagtgcg gcacccgcgt gtcgaactcc gcggcctccc ccgccgacag caccacgtcg
    14521 tgctcgccga gcacgagccg cagccgcccc gagaggacgt acagccactc gtacccctcg
    14581 tgggtgcgcg ggtccggctc ctcccggctc tggggctcca gcaccttgaa cgcctggagg
    14641 ccgcccgcct ggcgggtgag cggccagtgg gtgcggccgt ggcgcacgac gggcctggca
    14701 cgcacccggg ggtcgccgac cggtggcgcg ccgaccagtt cgtccagcgg cacctggtgg
    14761 gcccgggcga tcggcagcag cagttcgagg ctcggtctgc gcaggcccga ctccagccgc
    14821 gacagggtgc tcaccgagat gccggtcgcc tcggacagcg cggccagggt cacctcccgc
    14881 tccttgcgca cctggcggag cctcggcccg acaccggcga ggacgtcgtc tggggtcgtc
    14941 atgcatttat tgcagttccg gcaaacaaat ttgtcaatac cgtgggatcc gagcgacctt
    15001 ctacgtggag gtggtcacca tgacccagaa cacgaacctg aaggatccga aggacccgtc
    15061 cgggaggtac gacgtggtgg tcgtcggcgg cggcgcggcc gggctctccg ccgcgctcgt
    15121 cctgggccgc tcccggctgc gcaccctggt ggtcgacgcc ggtgagccgc gcaacgcgcc
    15181 ctcggaccac atgcagggct acctgacccg ggacggcatg tcccccgccg agttcctggc
    15241 cctcggccgg gaggagatcg cccgctacgg ggtggacctg gtccgcgacc gggcggtgga
    15301 cgtgtccagc gacggagact tcgcggtgga gctgggcggc ggggacaccg tgcacgcccg
    15361 ccggctgatc gtcaccaccg gtctcaggga cgagctgccg gccgtgcccg gggtcgccga
    15421 gcggtacggc cgggacgtgc tgcactgccc gttctgccac ggctgggagg tgcgggacga
    15481 acgcttcggc gtcctggcct cgagcccgct cagcgtgcac caggccctga tggtgtccgg
    15541 ctggtcggac gacgtgacgc tcttcctgca cacggtcgcc gagcgggagc tgtccgacga
    15601 cgacctgcgt cggctcgccg cggccggggt caaggtggtg cccggcgagg tggccgccct
    15661 gcgggtcgag gacgaccggc tgaccggggt gcggctggcg gacggcacgg cgcacgaccg
    15721 cacggtggtg ttcgtcgccc cgaaggcggt gccgcagacc ggcctgatgg agcggctggg
    15781 ggcggagttg caggagacgc cgttcggcgc ctaccccgtg gtggacccga cgggccggac
    15841 cagcgtgccg ggcgtgtgga ccgcgggcaa cgcgatgggc ttcgccgagc aggtcgtcca
    15901 cgcggccagc ggcgggtacc gcgcggcgtc ggcggtcgtc ggcgacctga tcatgtcggc
    15961 cctggacgcc gccctcgcgg agtgagggca ctgcggagca cccgggaagg gcgtacgcgg
    16021 gcgcgctcgg acgccgcggg gtgtacgccc gcccgctccg gtgcaccatg actgcatgct
    16081 gcttgcccgg ttggcccagg tgtcccggga ggtcgcggcc acgtcggcgc ggtcccggaa
    16141 gaccgtcctg ctcgcggagc tgttccgtga ggcggaggcg gcggacgtgc cggtcgtcat
    16201 cccgtacctg gcgggacggc tcccgcaggg ccggatcggc gtcggctgga aggtgctgag
    16261 ccgccgcgtg ccgcccgcgg acgcaccgac cctgaccgta cgtgacgtgg acgcccgcct
    16321 cacccggctc ggcgcggtct ccggcgccgg ttcgcaggcc gagcggaccc ggctggtcgg
    16381 cgagctgatg ggcgccgcca cggaggacga gcagcgcttc ctgatcgggc tgctcaccgg
    16441 ggaggtccgc cagggcgccc tggacgcggc cgccgtcgag ggcctggccg cggcgacgga
    16501 cgctcccccg gcggacgtgc ggcgggcggt gatgctcgcg gggtcgctcc agaccgtggc
    16561 cgaagccctg ctggccgacg gacccggcgc cctcgaccgg ttccggctca ccgtggggca
    16621 gccggtgctg ccgatgctgg cgcacagcgc gtcctcggtc gccgaggcgg tcggcaaact
    16681 gggcgccgcc gcggtggagg agaagctgga cggcatccgc gtccaggtgc accgggacgg
    16741 cggcaccgtg cggatctaca cccgcacgct ggacgacatc accgaccggc tccccgaggt
    16801 caccgaggcg gccctggcac tgcccggcga gcggttcatc ctggacggcg aggcgatctc
    16861 cctcgacgcg gacgggcgcc cccgctcctt ccaggagacc gccggccggg tcggctcccg
    16921 caccgacgtg gccacggccg cgcgggcggt cccggtctcc gcggtcttct tcgacgtact
    16981 ctccgtcgac ggccgcgacc tgctcgacct gccgctgacc gaacggcacg cggagctggc
    17041 gcggctggtc cccgagcccc tgcgggtacg gcgcactctg gtgcacggcc ccgaggacac
    17101 cggtgcggcg gaggagttcc tcgcccggac gctggcgcgc gggcacgagg gcgtcgtcgt
    17161 caaggggctc gacgccgcct acagcgcggg acggcgcggc gcgtcctggc tgaaggtcaa
    17221 gccggtccac acgctcgacc tggtggtgct ggccgccgag tggggccacg gccgccgcac
    17281 cggcaagctc tccaacctcc acctgggcgc ccgcaccgcc gacggctcct tcgcgatgct
    17341 cggcaagacc ttcaagggca tgaccgacgc gctgctgacc tggcagaccg agcgcctgaa
    17401 ggagctggcc gtggaggagc acggctgggg cgtgaccgta cgccccgagc tcgtcgtcga
    17461 gatcgcctac gacggcctcc agcgctccac ccgctacccg gccggcgtca ccctccgctt
    17521 cgcgcgcgtg gtccgctacc gcgaggacaa gcgccccgag gacgcggaca ccgtggacac
    17581 cctgctcgcc gcccaccccg gggtggcccc gtgaggcgca gcgcgggtct gctgctgcac
    17641 cggcgcgctc ccggcggggg gctccaggtg ctcctcggcc acatgggcgg cccgttctac
    17701 agccgccggg acgccggggc gtggaccgtc cccaagggcg agtacgactc cggggagccg
    17761 gcctgggagg cggcccggcg ggagttcgag gaggagctgg ggctgccgcc gcccgagggt
    17821 gaggccgtcc cgctcggcga ggtgcgccaa gcgggcggga agctcgtcac ggtctgggcc
    17881 gtggcggccg acctcgatcc ggcgacggtc gtgcccggca ccttccgcat ggagtggccg
    17941 ccgaggtcgg ggcggaccga ggagttcccc gaactggacc gggtggcgtg gttcggcctc
    18001 gaccgggccc gcgaggtgat cgtgaaggcg caggccgcgt ttctcgaccg gctggctgag
    18061 cactcgcact gacgagaggc gacgacggac ggcggcttcc ggacgcgcgg cggaccgcgg
    18121 cacccacctg cgggacccgt ccgcgttgcg gcaccccgcg ccgcgcgcca aggtcgaagc
    18181 acgaaggcac ccagggaggt cggccatgcc catcgcgacg gtgaacccgg cgaacggcga
    18241 gacgctcagg acgtacgagg ccatgggcga ggaggagatc gagcgccgga tcgagctcgc
    18301 ggaggccacc ttccgcacct accggaccac ggggttctac gagcgggccg ggctgatgcg
    18361 ccgcgccgcc gaccttctcg aggccgatca gaaggagatc gggaaggtca tcaccacgga
    18421 gatgggcaag ccggtgaagc aggcccgcgc ggaggcggcc aagtgcgcca aggcgatgcg
    18481 ctggtacgcc gaccacgcgg cggagctgct ggccgacgag gagcccgccg aggccgacgt
    18541 gaaggactcc ggcgcctccc gggccctggt ccgctaccgg ccgctcggcc cggtgctcgc
    18601 ggtgatgccg tggaacttcc cgctctggca ggtgatcagg ttcgcggcgc ccgcgctgat
    18661 ggcgggcaac gtcgggctgc tcaagcacgc ctcgaacgtg ccgcagaccg ccctctacct
    18721 ggaggacctg ttccaccggg cgggcttccc cgagggctgc ttccagacgc tcctcatcgg
    18781 ttccgcccag gtcgacgacg tcctgcgcga cgaacgggta cgggccgcca ccctcaccgg
    18841 cagcgagccc gcgggccgcg cggtggccgc cacggccggg gagatgatca agaagacggt
    18901 gctcgagctg ggcggcagcg acccgttcgt cgtcatgccg tccgccgacg tcgaacgggc
    18961 cgcggaggtg gcggtgaccg cgcgcaccca gaacgccggt cagtcgtgca tcgccgccaa
    19021 gcggttcatc gtgcacacgg acgtctacga cgccttcgcc cagcgcttca ccgagggcat
    19081 gcgggcgctg aaggtcggcg acccgatgga cgaggagacc gaggtcggcc cgctctccag
    19141 cgagcagggc ctgaacgacc tggtggagct ggtcgacgac gcggtgcgcg gcggcgcgag
    19201 cgtgctgtgc ggcggcgaac gtccggacgg gcccggctgg tactacccgc cgaccgtcct
    19261 ggcgggcgtc acccgcgagc tgcgcatcca ccgcgaggag gccttcggac cggtcgccac
    19321 gctctaccgg gcggccgacc tggacgaggc ggtcctgatc gccaacgaca cggacttcgg
    19381 gctcagttcg aacgtgtgga cgcgcgacga cgcggacgtg gaccgtttcg tccgggacct
    19441 ggaggcgggc ggcgtgtacg tgaacgggat gacggcgtcc cacccggcgt tcccgttcgg
    19501 cggggtcaag cggtcgggct acgggcgtga gctgtccggg cacggaatcc gcgagttctg
    19561 caacatcacc accgtatggc acggagcgtg agccttccgc gactacgatc ccctttgtga
    19621 accgcgaagt gaccctgcct ctgatcgtcg acgaccgcgg cacgctccag gtcgccgcgt
    19681 ccgacgtgag caagctgctg cgcacggtcg gcgggcggtg gctgcggctg gtggagaccg
    19741 gcgaggagag cctggacgag gacaccgtcg cggccctcac catcgagctg gccaagctgg
    19801 ccgaccggat cgacgtggcg tgcatcgccc acagcagcgg cccctcctcc tgacgcctgc
    19861 cgcccagctc cccgggacgg agtaacccgg cgggagatca ccgccccggt gagtgatcgt
    19921 ggatgggcac ccctgaaaag gtgcaccact ttccggccgg ggggcgcaag ccttccgcga
    19981 ggcgaaagca ggcacggttc atggcgactt tgtgcagacc ctcggtgtcc gtcccggagc
    20041 acgtgatcac gatggaggag acgctggagc tggcgcgtcg gcgtcacacg gaccatcctc
    20101 aactgccgct cgcgctccgg ctgatagaga acaccggggt ccgcacccgg cacatcgtgc
    20161 agcccatcga ggacacgctg gagcaccccg gcttcgagga ccgcaacaag gtctacgaac
    20221 gggaggcgaa gtcccgtgtc ccggccgtga tccagcgcgc tctggacgac gcggagctgc
    20281 tcgccaccga catcgacgtg atcatctacg tctcctgcac gggcttcatg atgccgtcgc
    20341 tcacggcgtg gctcatcaac gagatgggtt tcgacagcac cacgcgccag atacccatcg
    20401 cgcagctggg ctgcgcggcc ggcggtgcgg cgatcaaccg ggcccacgac ttctgcaccg
    20461 cctacccgga ggccaacgcg ctcatcgtgg cctgcgagtt ctgctcgctg tgctaccagc
    20521 ccaccgacct cggcgtgggc tccctgctct gcaacggcct cttcggcgac ggaatcgccg
    20581 ccgcggtggt ccgcggccgg ggcggcaccg gagtgcgcct ggagcgcaac ggctcgtacc
    20641 tgatccccaa gaccgaggac tggatcatgt acgacgtgaa ggcgaccggt ttccacttcc
    20701 tgctggacaa gcgggtgccg gccaccatgg agccgctcgc gccggcgctc aaggagctgg
    20761 cgggagagca cggttgggac gcctccgacc tggacttcta catcgtgcac gcgggcggcc
    20821 cccggatcct cgacgatctc agcacgttcc tggaggtcga cccgcacgcg ttccgcttca
    20881 gccgggccac gctcaccgag tacggcaaca tcgccagcgc cgtcgtcctg gacgcgctgc
    20941 gcaggctctt cgacgaaggc ggcgtcgagg agggggcacg tgggctgctg gccggcttcg
    21001 gtcccggcat caccgcggag atgtcgctgg gctgctggca gacggcggac gtgcggcggg
    21061 gcatacggca ggacgtgacg cggaccgcgg cacggggcgt gtcgcggagg gtgaggcagg
    21121 catgactgaa gaaacgattt cccaggccgt gccacccgtc cgggactggc cggccgtcga
    21181 ccttcccggc agcgacttcg acccggtgct gaccgagctg atgcgcgagg gtcccgtcac
    21241 ccggatctcg ctgcccaacg gcgagggctg ggcctggctc gtgacccgcc acgacgacgt
    21301 ccgcctggtc accaacgacc cccggttcgg gcgcgaggcc gtcatggacc gccaggtcac
    21361 ccggctggcc ccgcacttca tcccggcgcg cggcgcggtg ggcttcctgg acccgcccga
    21421 ccacacccgg ctgcgccgct cggtggccgc ggccttcacc gcgcggggcg tggagcgggt
    21481 gcgcgagcgg tcccggggca tgctcgacga gctggtcgac gccatgctga gggccggtcc
    21541 gcccgccgac ctcaccgagg cggtgctgag cccgttcccc atcgcggtga tctgcgagct
    21601 gatgggtgtg ccggccaccg accggcactc catgcacacc tggacccagc tgatcctgtc
    21661 ctcctcgcac ggcgccgagg tcagcgagcg ggccaagaac gagatgaacg cctacttctc
    21721 ggatctcatc gggctccgct ccgacagcgc gggcgaggac gtcacctcgc tgctgggtgc
    21781 cgccgtgggg cgggacgaga tcacgctgtc ggaggccgtc gggctcgcgg tgctgctcca
    21841 gatcggcggc gaggcggtca ccaacaacag cgggcagatg ttccacctgc tgctgagccg
    21901 cccggagctg gccgaacgcc tgcgctccga gccggagatc cgcccccggg ccatcgacga
    21961 gctgctgcgc tggatcccgc accgcaacgc cgtggggctg tcccggatcg ccctggagga
    22021 cgtggagatc aagggggtgc ggatccgcgc gggcgacgcc gtctacgtct cgtacctggc
    22081 ggccaaccgc gacccggagg tgttccccga cccggaccgc atcgacttcg agcgctcccc
    22141 caacccgcac gtctccttcg gcttcggccc gcactactgt cccggcggca tgctggcgcg
    22201 gctggagtcg gagctgctcg tcgacgcggt cctggaccgc gtgccggggc tgaagctcgc
    22261 ggtggcgccg gaggacgtgc ccttcaagaa gggtgcgctg atccgcgggc ccgaggccct
    22321 gccggtgacg tggtgagcgg cctggtcgcg gcggccgagg gcctgctggt gccgcccggt
    22381 cagggcaggg tggtgcaggc gccggcccag cacgtgacct tcaaggtgac cggttcgcac
    22441 tcacgcatgg cgtccacctt cgaggtgatc gtgccgccgg ggttcgacgt cggcgcccat
    22501 gtgcactccc gcagcgagga gctgttctac gtgctggagg gcgagctgga cgtgctcgcc
    22561 ttcgagccgc ggatccgtac gccggacagc tggcgggagt gggagtcgac ttccggcaac
    22621 cgggtggtgc gcgccacccc cggaacggtc atcgtcgtac cccccggctg tccgcacgcc
    22681 ttcgcgaacc cgacgggcga gccggccaag atgttcttcc aggccagccc gcccccggac
    22741 cacgagcgct acttcgagga actgctggag atcctcggcg agggcggccc gccggaccac
    22801 gaggcgatcg aggccctgcg ggcgaagtac gacatcgagc agctcacgcc gctgcgacac
    22861 ggttagcgga tcggcatccc ggccagcgtc cgcgcgatca ccagccgctg gatctcactc
    22921 gtgccctcga agatcgtgta gatcgcggag tcccggtgca tccgctccac cgggtactcc
    22981 cgcgtgtagc cgttgccgcc caggatctgg accgcctggg cggtcacctt cttcgcggtc
    23041 tcgctcgcga acagcttgga catcgagccc tcggccgccg tgaacggctt gccgttgatc
    23101 gccatccagg aggcccgcca caccagcagc cgggccgcgt cgatggacgt gcgcatgtcg
    23161 gcgagctgga aggcgacgcc ctggttgtcg atgatggggc gcccgaactg ctcccgggtc
    23221 tgcgcgtact ccagcgccac ctcgtacgcg gcgcgcgcgg tgcccaccgc catcgccccg
    23281 accgccgggc gggacgcctc gaaggtggcc atcgccgcgt tcttcacgcg ctcgccgccc
    23341 ttcttggcct tctcccgggc gcgggccagg cgggcgtcca gcttctcctt gccgccgagc
    23401 aggcaggagc cgggcacgcg cacgttgtcg aggacgacct cggcggtgtg cgaggcgcgg
    23461 atgccgtgct tcttgaactt ctggccctgg gacagcccgg gcgtggccgg cgggacgatg
    23521 aaggaggcgt ggcccttgga gcccaggtcc gggtcgacga ccgcgacgac gacgtggacg
    23581 ttggcgatgc cgccgttggt cgcccaggtc ttggtgccgt tgagcaccca ctcgtccttg
    23641 gcctcgtcgt acacggcacg cgtgcgcatg gaggcgacgt cggagccggc gtcgggctcg
    23701 gaggagcaga aggcggcgac cttgacgtcg ttggcgtcgc cgtacatctg cgggatccag
    23761 gtgccgatct gctcctcggt gccgttggcg aggacgccga cggcggcaag gccggtgccg
    23821 acgatcgaca gggcgatgcc cgcgtcgccc cagaacagct cctccatcgc catggggatg
    23881 ccgaggccgg tggagtcgaa gtactgctgg gcgtagaagt ccagggagta gatgccgacc
    23941 ttggcggcct cctggatgac cggccagggg gtctcctcgc gctcgtccca ttcggcggcc
    24001 gcggggcgga tgacatcggc cgcgaagccg tgcagccagt cccggacctc cttctgttcg
    24061 tcgctcagct ccatggtgaa ctcggccatg tcccctccag tgacgcccgt gcatgttact
    24121 tgcggtaaca ccgagtctgt tacccgtggg taggaaaagt caactcccgg gaccacctcg
    24181 ccctcccgtt cgatggccct cgtcccgtga gtgttagttt gcgcaggcgt caccgaaaca
    24241 gcacgggtgg ggagagcaca tgaacaccac gcagcgggcc gatcagcaga catccgccga
    24301 ccgcagacgg cgcgagctgc tcgaggccgc cgaccgggtg gtgctgcgcg acggtccgca
    24361 cgcctcgatg aacgccatcg ccgccgaggc gggcatcacc aagccgatcc tgtaccgcca
    24421 cttcggcgac aagggcggac tctacgccgc cctcgccgtc cgccacacgg acgccctgct
    24481 cgcctcgctg cgggccgccc tggacgctcc ggcccagcgc cggcagcgcg tggaggccac
    24541 cctggacacc tatctggcgg ccatcgaggc ccgtccgcag gtgtaccgct tcctgatgca
    24601 tccggcggag agcgccggca ccccgggcga ccagtccgag cagggcttcg acgtcggcaa
    24661 gcactcggcg ccgctgctgc gccgcatggg cgaggagctg gcccaggtca tcgaggagcg
    24721 cctcgacgtc gggccgggca cccagcagct ggcccgggtc tgggggcacg gcatcgtcgg
    24781 catgatgcac gccgccgggg actggtggct gggtgaacga ccctgccccc gcgaggagtt
    24841 ggtgcgcacc ctggccgatc tgctgtgggg ccgcctcgcc gaggccggcg acaaggaggg
    24901 cggtcccggg ttctgacccc cggcctcgcg cgccccggtc gtcgtcgggg agggcgttca
    24961 gcggtgccag gacgcccgcg ccacctggcg catcagcttg cggtggcgcc ggccggtcag
    25021 gcgatcggcg tagacccgtc cctccaggtg gtcgcactcg tgctggaggc accgggcgaa
    25081 gaaccccgtc ccgcgcacgg tgaccggctc acccgccacc gtgaagcccg tcaccaccgc
    25141 ctcgtcgtac cgctcggtcc ccgcctccag acccggcagc gacagacagc cctccggacc
    25201 gcgcaccacc acaccgccgg tctccaccag ccgggggttc accacgtgcc cgaggtgccg
    25261 ctcgtcctcg tcgtccgggc agtcgtacac gaagacgcgc accgcctcgc cgacctggtt
    25321 cgcggccagg cccacgccgt gggcggcgta catggtcgcg aacaagtcct ccacgagcgc
    25381 cgcgagttcc ggaccgaagt ccgtcacctc cgcgcagcgg gcgtgcagga cggggtcgcc
    25441 gaggaggccg aggggacgga cgcgcccgtg ggcgcccggg atggagcctt gtcgcatggc
    25501 ggtcagagta aggtccctgt gtcccccggc ggcaggcgcc caccgccgga accggtggcc
    25561 ggtgccgcga ttcgggagtg cgaatggatc tcgataggct gaggtccaca ccacgtggcc
    25621 gtcaggcttc acaggcttca ggcgcggcgc gtacggcaag gaggatcgag aactgatggc
    25681 aggcaactcg gacccgctca cgccgcgggc caagatcgcc gtgaccgcgg gcaaggcggt
    25741 cgcggcggca tcgcgcgccg cggggcgcgg cagcggttcg gtgatcggcg gccgggtcgc
    25801 gctgaaactc gaccccgacc tcctcggccg gctcgccggg cacctggacg tgaccctggt
    25861 ctcggcgacc aacggcaaga ccaccaccac ccggctcatc gccgaggcgc tcaaggcggc
    25921 cggtccggtc gtctccaacg cgctcggcgc caacatgccg gccggcatca cctcggctct
    25981 cgcgggcggc gcggacgccc gctacggggt catcgaggtc gacgagaagt acctcgtcgg
    26041 cgtcgcccag gccaccgacc cgaagtgcat cgcgctgctc aacctctccc gcgaccagct
    26101 ggaccgcgcc gccgagaccc gcatgctcgc cgagaactgg cgcgagggcc tggccggctc
    26161 gaaggccgtg gtcgtcgcca acgccgacga cccgctggtg gtgtgggccg cgtcctcctc
    26221 cccgaacgtg atctgggtcg ccgccggaca gatgtggaag gacgacgcct ggtcctgccc
    26281 gtcctgcggc ggcgtcatgc agcgcccggg cgacgactgg ttctgcggcg agtgcggctt
    26341 ccgccgcccg acgccgagct gggcgctgtc cggcgaccac gtgctcgacc cgcacggctc
    26401 cgcgtggccg atccacctcc agctgccggg ccgcgccaac aaggccaacg ccgcctcctc
    26461 ggccgccgtc gccgccgtct tcggggtgcc gccgcaggtc gccctggagc gcatgtacca
    26521 ggtgcaggcc gtcgccgggc gctacgacgt cgtccagttc cagggccgcg acctgcgcct
    26581 gctgctcgcc aagaacccgg cgggctggct ggagaccttc tccctgatcg acccgccgcc
    26641 ggccccggtg atcctctcgg tgaacgcgcg cggcgccgac ggcaccgaca cctcctggct
    26701 gtgggacgtg gactacaccc ggctgtccgg ccatccgatc tgtgtggtcg gcgaccggaa
    26761 gctggacctc gcggtgcgcc tggaggtcgc gaaccagcag ttccaggtgt gcgaggacct
    26821 cgaccaggcg gtgcagctgt gcccgccggg acgcatcgag gtcatcgcga actacaccgc
    26881 cttccaggac ctgcgccgcc gcgtcggcaa ctgaccgcga gacttcaggg gattttcgtg
    26941 agcgacaacc aactgcggat cgtctggatc tacccggatc tgctcagcac ctacggcgac
    27001 cagggcaacg ccctcgtcgt ggagcgccgg gcccgccagc gcggactcga cgtggcccgg
    27061 ctcgacgtac gcagcgacca gccgattccg acctccggcg acatctacct cgtcggcggc
    27121 ggcgaggacc ggccgcagcg gctcgcggcc gagcggctgc gccgtgacgg cggcctgtac
    27181 cgggcggtgg agaacggcgc gatcgtcttc tcggtctgcg ccggctacca gatcctgggc
    27241 cacgagttca tcaacgacct cggccagcgc gagccgggcc tcggcctgct cgacgtggtc
    27301 tccacccgcg gcgagggcgc ccggtgcgtc ggcgacgtcc tcggcgacat cgacccgcgc
    27361 ctcggcctgc ccccgctgac cggcttcgag aaccaccagg gcgtcaccca cgtcgggccc
    27421 aacgcccgcc cgctcgccca ggtccgcttc ggcaacggca acggcacggg ggacggcacg
    27481 gagggcgcgt acaacgacac ggtcttcggc acctacatgc acggccccgt gctggcccgc
    27541 aacccgctga tcgcggacct gctgctcaag ctggccctcg acgtgaacgc gctgccgccg
    27601 accgacgacc gctggtacga ggcgctgcgc aacgagcgca tcgcggccgc gcagcagcct
    27661 gcctgaccct ggcggggcgg gcccgtctga tgccccgtcc gcacaggtga gcggactcgt
    27721 ccagtaggcg gacgcacggt tcggtcccgc cccccgatgc cgctagggtg gcggggatcg
    27781 agccggacag cgcggtccgg acccgtgcca cgttgagaag gtatttcggg ctatgcgcat
    27841 tggtgtcctc acgtccggcg gcgactgccc cggcctgaac gccgtcatcc ggtccgtcgt
    27901 gcaccgcgcc gtcgtcgacc acggcgacga ggtcatcggt ttccgggacg gctggaaggg
    27961 cctcctggag tgcgactacc tcaagctcga cctcgacgcg gtcggcggca tcctggcgcg
    28021 cggcggcacc atcctcggct cctcccgggt ccgacccgaa cacctgcggg acggcgtgga
    28081 gcgggcccgg ggacacgtcg aggaactcgg cctcgacgcg atcatcccga tcggcggcga
    28141 gggcacgctg aaggcggccc ggctgctgtc cgacaacggc ctgccgatcg tgggcgtgcc
    28201 gaagaccatc gacaacgaca tagcggtcac cgacgtcacc ttcggcttcg acaccgcggt
    28261 gaccgtcgcc accgaggccc tggaccggct gaagaccacc gccgagtccc accagcgggt
    28321 gctgatcgtc gaggtcatgg gccggcacac cggctggatc gcgctgcact cgggcatggc
    28381 cgcgggtgcg cacgccgtcg tcgtcccgga gcggcccttc gacatcgacg agctgaccgc
    28441 gaaggtcggg gagcgtttct ccgcgggcaa gcggttcgcg atcgtggtgg ccgcggaggg
    28501 tgccaagccg aaggccggga ccatggactt cgacgagggc ggcaaggacg tctacggcca
    28561 cgagcgcttc gccgggatcg cccgccagct ctccatcgag ctggaggagc ggctcggcaa
    28621 ggaggcccgg ccggtgatac tcgggcacgt ccagcgcggc ggcacgccga cggcgtacga
    28681 ccgggtgctg gcgacgcggt tcgggtggca cgcggtggag gcggtgcacc gcggggagtt
    28741 cgggaagatg acggccctgc gcgggacgga catcgagatg gtgtcgctcg ccgacgcggt
    28801 ggagtcgttg aagacggtgc cggacgcgcg gtacgcggaa gcggagtgtg ttctctgacc
    28861 tgccggtcgg agctcgggcc ttgaggtgat tcgcggtctg cgggccggtg tggcttgtcg
    28921 cgcagttccc cgtgcccctt tggggcgctt tccccgcccc cggtcgcaga tgtggccggg
    28981 ggcggttcta cgcttggctc ggacaagcgg cgttcaaccg cgctcaaccc ccacgaaaca
    29041 ggagcgggcg gatggatcac agcgggcacg gcatgacgat ggatctgccg ccgttcacgc
    29101 tggggcgggg tctcgcctgg tcggcggatc ccttcttcct ggtcgcctgc ctcctgggac
    29161 tggcgctgta cgggtggggc gtcgcgcgtc tggtgcggcg cggtgacaag tggccggtcg
    29221 gccggaccgt ggccttcgtg gccggtgtgc tgagcgtcgc cctgatgatg tgcaccaagc
    29281 tgaacgacta cggcatggtc atgttcagcg tgcacatggt ccagcacatg gtgatcagca
    29341 tggtgtcgcc gatcctgctg ctgctcggcg ccccgatcac gctggccctg cgcgcactgc
    29401 cccccgcggg gcgtggccgc aagggtcccc gtgagctgct gctgatgctc ctgcacagcc
    29461 gctacatgcg gatcatcacg cacccggcgt tcaccattcc gctgttcatc gcgagcctgt
    29521 acgcgctgta cttcacgccg ctcttcgaca ccctgatggg ctcgcaggcc gggcacatcg
    29581 ggatgatggt gcacttcctc gccgtgggcg tggtgttctt ctggccgatc atgggcgtcg
    29641 acccgggccc gcaccggccg ggctacctga tgcggatgct ggagctgttc gcgggcatgc
    29701 cgttccacgc gttcttcggc atcgcgctga tgatggcctc ctccccgatg gtcgagacgt
    29761 tcaagaaccc gcccgcctcg ctcggcatcg acgcgctctc cgaccagaac gcggccggcg
    29821 gcatcgcctg ggccttcagc gaggtcccct ccgtgctggt gctgctcgcg ctgctcttcc
    29881 agtggtacgc ctcggaggag cgccaggccc ggcgcagcga ccgggccgcc gaccgcgacg
    29941 gcgacaagga gctggcggcc tacaacgcct acctggcctc actgaacaca cgcggcggct
    30001 gaacggggca ccatggaggg caacggacac gaggagggtg ttgcgatgcc cggttccacg
    30061 gacagttcga cgaagacgat gggggcgctc accatcggcg gcctcgtcgc ggtgacggcg
    30121 tacacggtgg cgctcgggag caacggctgg ctgtggttcg gctgggtcgt gctcggtctg
    30181 atcaccctgg ggctggtggc cacgcgcagc gcctgagccc cgcgtggggc gcccccgtcg
    30241 ctcggcgggc cggctcagtc gcgaccgagc cggcccgccg agtgcacgcc cggctggtac
    30301 ttcggcagcc ggaccgtgat cttcatgccc gcgccgacgg ccgtctcgat gaccaggccg
    30361 tgggcgtctc cgtagacctg gcggaggcgg tcgtcgacgt tggacagccc gatgccgccc
    30421 gacgggctga cctcgcgcgc gaggatgcgg cgcagcaggt cggggtccat gccggcgccg
    30481 tcgtcctcga tgacgaccag ggcctcggcg cccgcgtcct gggcggtgat ctggatgcgg
    30541 caccggtccg ccttgccctc caggccgtgc ttgacggcgt tctccaccag cggctggagg
    30601 cagaggaagg gcagcgcgac cggcagcacc tcgggggcga cctggagggt gacggcgagc
    30661 cggtcgccga agcgggcccg cacgagcgcc aggtagtggt cgatggcgtg cagctcgtcg
    30721 gcgagggtgg tgaagtcgcc gtgcctgcgg aacgagtagc gggtgaagtc ggcgaactcc
    30781 aggagcagct cgcgggcgcg ctcggggtcg gtgcgcacga aggacgcgat gaccgcgagc
    30841 gagttgaaga tgaagtgcgg ggagatctgg gcgcgcagtg ccttgatctc ggcctcgatg
    30901 aggcgggtgc gggactggtc gaggtcggcc agctccagtt ggacggagac ccatcgggcc
    30961 acctccccgg cggcgcggac caggacggcg gactcgcggg gcgcgcaggc aacgagggcg
    31021 ccgtgcaccc ggtcgtcgac ggtgagcggg gcgacgacgg cccagcgcac cgtgcagtcc
    31081 ggagtgtcgc aggagagccg gaaggcctcg ccgcggccgg tgctcagggg tcccgcgagg
    31141 cgttccatga tctcggcgcg gtggtggttg cccacgccgt cccagaccag gacctcttcg
    31201 aggtccgtca gacacagcgc gtccgtgccc agcagggagc gcagcttgcg ggccgacttc
    31261 ccggcggtct cctcggtcag gcccgcccgc agcgggggcg tggccaggga cgcggtgtgc
    31321 agggtctgga aggtggcgtg ctcgaccggg gtgcccaggc cgccgaggtg ctgcgggcgg
    31381 gccgtgcgcc gcccgagcca gaatccggcg gccagcagcg ggagcagggc cacggcgaga
    31441 cccgccagga agccgcccac ggagccgctc accgcgtcgg ctcctcgcgc acgtcgcgca
    31501 cctcgcgcac ctcgggcagg tcggccgccg tctccaggtc gtcggtacgc aggtcgtccg
    31561 tgcgcaggtc gtccgtgcgc aggtcgtccg tgcgcagttc ctccgcgtgc agctcctccg
    31621 gcaggtggaa gcgggccagg atcgccgccg tcccggccgg cacccggccc ggggtggcga
    31681 gggacaccag caccatggtg aggaagccca gcggcaccga ccacagggcg ggccaggcca
    31741 gcagcgcgtg cagggacccc ccgccgcccg ggaagccgcc catggtggca gccacggcga
    31801 gcagtgcgga accgccgccc accagcatcc cggcggccgc gcccggcggg gtcagccgtc
    31861 gccaccagat gccgaggacg aggagcgggc agaaggagga ggcggacacg gcgaaggcga
    31921 ggccgacggc gtcggcgacc ggcagcccgc cgaccagcgc gctcgccgcc agcggcacgg
    31981 ccatggcgag cagggtgccg agccggaagt gcggcacggc gcgggacggc agcacgtcct
    32041 gggtgaggac gcccgcgacg gccatggtga gccccgacgc ggtggacagg aacgcggcga
    32101 aggcgccgcc cgccaccagc gcgccgagca ggtcgccgcc cactcccccg atcacccggt
    32161 cgggcagcag caggaccgcg gcgtcggcgt ccccggtgag ggtcagctcg ggggcgtaga
    32221 ggcggccgag ggcgccgtag aggggcggca gcaggtagaa ggcgccgatg aggccgagca
    32281 cggcgacggt ggtgcggcgg gcggcgacgc cggtcgggct ggtgtagaag cgcaccacga
    32341 cgtgcggcag gcccatggtg cccaggaagg tggcgaggat caggccgtac gtggcgtaca
    32401 gcgggcgttc cgtgcggctc tcggcccggg agggggacag ggcgtcgtcg gcgccgcggc
    32461 cggcggccgg gacgggggtg tgtgcggcga aggtgaggcg ggcgccggcc tcgatgcggt
    32521 gggtgcccgc gggcagggcg acgcggtcgc cgtcgtgggc gcggccgtcc acggtgccgt
    32581 cgacggtcac ggtcagcggc tcctccagct tgagggtgag actgtcgtcg acccgcaccg
    32641 aacgctgctc ccggaaggtg gcgggttcgt cgaaggggcg gccgggggcg ccgtcgccct
    32701 gccaggccag caccaggaag agggcgggga cgagcagggc ggtgagtttg agccagaact
    32761 ggaaggcctg gacgaaggtg atgctgcgca tgcccccggc ggcgacgatg gcggcgacga
    32821 cgaccgcgac gatcaccccg cccagccagt cgggcgctcc gctgagcacc gtcagcgtca
    32881 gcccggcgcc ctggagctgc ggcagcaggt agagccagcc gactccgacg acgaaggccc
    32941 ccgcgagccg ccgcaccccc tgggaggcga gccgggcctc ggcgaagtcg ggcagcgtgt
    33001 aggcgcccga gcggcgcagc ggggcggcga cgaacagcag caggacgagg tagccggcgg
    33061 tgtagccgac cgggtaccag agcatgtcgg ggccctggac gaggaccagt cccgcgatgc
    33121 cgaggaagga cgcggcggag aggtactcgc cgctgatggc ggcggcgttg aggcgggggc
    33181 cgacggtgcg ggaggcgacg tagaagtcgg aggtggtgcg ggagatgcgc agcccgaagg
    33241 cgccgacgag gacggtggcc acgacgacga gggcgacggc gggtatggcg tagctggagt
    33301 tcatggtgcc ttcacggcct cgtccggcat ggtcaccggt cctcgacgag ccgcacgaag
    33361 tcgcgttcgt tgcgctcggc gcggcgcacg taccagcggg cgagcaggac cagcggggcg
    33421 tacaggccga agccgaggac ggcccactcc aggcgccggg cgtcgggcag cgccgcgaac
    33481 agcagcggca gcggcccgac gaggaggccg agcacggcga gggcggtgag accggcgcgc
    33541 agctggctgc gcatcaggga gcggacgtag gtgtgaccga gggtggtctg ctcgtcgatc
    33601 tcggtgcgcg gccggtagtg gccggtggcc tgcgggtggc gcccgcggga gcggagccgg
    33661 gcgggcggga cggtgcgccg gggcgggccg gtgacggtga cgcggcgttc ggtggggtcc
    33721 tggggcacgg ctcacggcct ccgcatgagc aggtcccgca gttcgcgggc gtggcgccgg
    33781 ctgacctgga gctcctcggt gccgaccagg acgctgacgg tgccggcgtc aagccggagt
    33841 tcgccgacgt ggcgcagggc gacgaggtgc cggcggtgga tgcggacgaa gccgcgggcc
    33901 cgccagcgct cctccagggt cgacagcggg atgcggacga ggtgactgcc ccggtcggtg
    33961 tgcaggcggg cgtagtcgcc ctgggcctcg acgtgggtga tctcgtcgac ggggacgaag
    34021 cgggtgacgc cgccgagttc cacggtgatg tggtcggggt cgggttcgtg caccgggatg
    34081 cgcggggcgg gcacggcggc ggtgccgcgc tgctcggcga cccggcgcac cgcttccgcg
    34141 agccgctccc tgcgcaccgg tttgaggacg tagtcgacgg ccttcaggtc gaaggcctgg
    34201 acggcgaagt cctcgtgcgc ggtgacgaac acgaccagcg gcggccgggc gaacccggtg
    34261 agcagccggg cgaggtccag tccgtccaga ccgggcatct ggatgtcgag gaagacgacg
    34321 tcgatggcgt cgggaccgcc ggggcccgtc tccagggccc ggttgatgcg gcgcagcgcc
    34381 tcggtcgtgt cgctcgctcc ctccgccgtg ccgatgcggg ggtcggcgtt cagcaggtac
    34441 acgagttcct cgagtgtggg ccgttcgtcg tcgacagcca gggcgcgcag catgaacgtg
    34501 gagtgtaggg gcgatccggg cgcctgcaca cgcctgcgac gtgccggtat cccctagata
    34561 cagtgcccgc atgaacagca ggcccgcttc gttcgacgaa ctcgaccgga agatcgtcac
    34621 cgccctgatg gaaaacgccc ggacgtcctt cgccgagatc ggcgcggaga tcggactgtc
    34681 gtccacggcg gtcaagcgcc gggtggaccg gctccgcgag accgacgtga tcaccgggtt
    34741 ctcggcgacg gtgcggccct ccgcgctcgg gtggcgtacg gaggcgtacg tggaggtgta
    34801 ctgcgagggg gcggcgccgc cgcggcggct cgcggaggtc gtgcggggct acccggagat
    34861 caccgcggcg atgacggtga ccggcggcgc ggacgcgctg ctgcacgtgc gggcgcgcga
    34921 cgtggagcac ttcgaggagg tgctggagcg gattcgtgcg gagccgttca tccggaagac
    34981 gatcagcgtg atggtgctgt cccacctgat cccggacagt cccgaggcag gggcggccct
    35041 gctcgcaccc aaggacgcag cggacgtgcg ctgacctggg gtacaacgca gcgatcctgc
    35101 gggaacacgc agctttcgtc gcttgtcggg cgcggtcgcc acttcttacc gtggtgtcaa
    35161 caccccgtca cacaccgtga aaagcggagg tacccctctg tgaccgagtc ccgtgtgcag
    35221 cgccggcggc gcttcgtggt ctgcgaaccc agacacttcg ccgtgcagta cgcgatcaac
    35281 ccgtggatga gcaccggccg acccgtcgac gtcatccgcg ccctcgacca gtggcaggca
    35341 ctggtcgaca cctaccgtgc ccacggccac accgtggaca ccgtcgcgcc ggtccccgga
    35401 ctgcccgaca tggtcttcgc cgcgaactgc gcggtcgtgg tcgagggccg ggtcttcggc
    35461 tccctcttcc acgcgcccga gcggcgtccg gagtccgtgc cgttcgaggc gtggttcaag
    35521 acggagggct tcgaggtcca ccaccccgag tcggtctgcg agggcgaggg cgacctggtc
    35581 ccggccggcc gctggatcct ggccggcacg ggttttcgca ccacccgtgc ggcccatcgc
    35641 gaggtgcagg agttcttcgg tgtgccggtg atctcgctga ccctggtgga cccgtacttc
    35701 taccacctgg acacggccct gttcgtgctc gacgacggga ccggcgggga gggccggagc
    35761 ggggggagcg caggcagtgg cgggaacatc gcctactacc cgggcgcctt ctcgcccggc
    35821 agccgcgagg tgctggagcg gctctacccg gacgcggtga tcgccacccg cgaggacgcg
    35881 ctggcgttcg ggctcaactc cgtgtccgac ggacggcacg tgttcatcgc gcccgaggcc
    35941 cgggggctgg ccgaccggct cgccggccgc ggctacgtgc cggtccccgt cgacctgtcc
    36001 gagttccaca aggccggtgg cggcatcaag tgctgcaccc aggagatccg ggagacccgc
    36061 tcatgaccgc acccgtccgc accgcccgcg gctccgagga actgatccgc gcggaggagc
    36121 ccgtcctcgc gcacaactac cacccgctgc ccgtcgtcgt ggcccgcgcc gagggcgcct
    36181 gggtcgagga cgtcgagggc cgccgctacc tggacatgct ggccggctac tcggcgctca
    36241 acttcggcca tcgccacccg gcactggtcg aggccgccca ccggcagctg gaccggctca
    36301 cgctcacctc gcgggccttc cacaacgacc ggctcgcggg cttcgccgag cggctggccg
    36361 cactgaccgg cacggacatg gtgctgccca tgaacaccgg cgcggaggcg gtggagagcg
    36421 gcatcaaggt ggcccgcaag tgggcctacg acgtcaaggg cgtcccggcc gaccgggcga
    36481 cgatcgtggt cgcggcggac aacttccacg gccgtacgac gacgatcgtg agcttctcca
    36541 ccgacgagac cgcccgctcc ggcttcggcc ccttcacccc gggcttccgg atcgtgccgt
    36601 acaacgacct cgcggcgctg gaggcggcgg tcgacgagac gacggcggcc gtgctgatcg
    36661 agccgatcca gggcgaggcg ggcgtgctga tccccgacga cggctatctg gccggggtgc
    36721 gggagctgac ccgccgcaag ggctgcctgt tcgtcgcgga cgagatccag tccggtctgg
    36781 gccgcacggg gcacaccctg gccgtcgagc acgagtcggt cgtgccggac gtggtgctgc
    36841 tcggcaaggc gctgggcggc ggcatcgtcc cggtgtcggc ggtggtcggc cggcgtgacg
    36901 tgctgggtgt gctgcacccg ggcgagcacg gttcgacgtt cggcggcaat ccgctggccg
    36961 ccgcggtggg cacggcggtg gtggaactgc tggagaccgg cgcgttccag cgccgggcgg
    37021 ccgagctggg cgcggtgctg cgcgaggggc tggccgccct ggtcggcagg ggtgtcgtcg
    37081 gcttccgggc gcgggggctg tgggcgggcg tggacgtgga cccggcgctg ggcagcggac
    37141 gcgagatcag tgagcggctg atgcgcgagg gcatcctggt caaggacacc cacggctcca
    37201 cgatccgcct ggccccaccg ctgaccgtca cggccgagga gctgacgggc gccctgggga
    37261 cgctggagaa ggtcctcacc tcctgacccg caccccgggg ttcaccgagc ggctcggcgg
    37321 tcctcgtcga gccgctccac gtgcgcgacg ttgtcccggt cctcggcgtc cgtactcggg
    37381 ccgcccgcga accaggcgtc gaggatctcg cgcagcaacg gagcggacgt cagccgcagg
    37441 ccgatggcga gcacgttggc gtcgttccag cggcgggccc cgtcggcggt gtacgcgtcg
    37501 gcgcacaggg ccgcacggac gcccggcacc ttgttggccg cgatggacgc gccggtgccg
    37561 gtccagcagc acacgacggc ctggtcggcc cgtccctcgg cgacctcgcg cgccgcccgc
    37621 tcggaacagg cggcccaccg cgggtccgcc ccggggctca gcgcgccgta cgcgcgcacc
    37681 tcgtgaccgc gtgcgcgcag ttcctcgacg aggagccggg ccacgggttc gtccatgtcg
    37741 gaggagacgg agatacgcat gtgcgaagcg tactcaccgg ccgctcacct catcggccca
    37801 accacatgac cgaagtcacc accataccca gcatgatcgg gggaacgggt acgacctgag
    37861 agacgtacga ccgagcagcg ctccgtccgg agtgtctgcg cgtggaaagg gaggccgcca
    37921 cgtcccccac cgagaacgga ccggagaccg acgccgcggc ggtgcgccgc caccccgccc
    37981 tcttccgggc gatcaagcgc cggcagaacc cccggctgcg ccggtcggac atcaccgtca
    38041 cggacgaggc cgcggtcaag cgagccgtca aggcggcctc cctcggcaac gccatggagt
    38101 ggttcgactt cggcatctac gcctatctgg cgggcacgat cggccgggtg ttcttccctt
    38161 ccgggagcga caccgcgcag ttgctctcct cgttcgccac gttcgccgtg gcgttcctgg
    38221 tgcggccgat cggcggcatg gtcttcggcc cgatgggcga caagatcggc cgcaagaagg
    38281 tgctggcgct gacgatgatc ctcatggcga tcggcacggc cgccatcggg ttcatcccca
    38341 gctacgactc catcggcttc tggtcgccgc tgctgctgat cctgttccgc ctgctccagg
    38401 gcttctccac cggtggcgag tacggcggcg cgtccacctt catcgccgag tacgcgccgg
    38461 acaagcggcg cgggttcttc ggcagcttcc tggagctggg gacgctggcc gggtacaccg
    38521 ccgccgccag tctggtcacc gccctgaccg ccgttctggg cagcgacggc atggactcct
    38581 ggggctggcg cgtcccgttc ctggccgcgc ttccgctcgg catgatcggt atctacctgc
    38641 ggctgcggct cgacgacacg cccgcgtacc tgaagctgga ggactccaac gtccacgtct
    38701 cggaggccgc gacggcggtg gagaccaccg cacggggcga cctcgccaag atcttccgca
    38761 cccactggcg ggcgctggtg ctgtgcatcg cgctggtcgg cgcgtacaac atcaccgact
    38821 acatgctgct gtcgtacatg ccgacgtatc tctcggacga gctggattac agcgagagcc
    38881 acggcctgat gatcctggtg gcgacgatgg tgctgctgat gctgatcatc aaccaggtcg
    38941 gccggctgtc cgaccgcttc gggcgcaagc ccgtcctgat gaccggcatg atcgggttct
    39001 tcgtgctgtc cgcaccggcc ttcgtgctgg tgcaggaggg cagtctgctc gccgtttcgg
    39061 gcggcatgct gatgctcggc ctgtcgctgg tctgcctgct gggcacgatg tcggcggcgc
    39121 tcccggcgat gttcccgacc aacgtgcggt acgggtccct gtcggtcggc tacaacctgt
    39181 cggcgtcgct gttcggcggg accacgccgc tggtgatcac cgcgctgatc agcgtgaccg
    39241 gctccgacat gatgcccgcc tactacgcga tggcggcggc cctgatcggt gtggtggccg
    39301 tggcctgcat gaaggagacg gcccagcagc cgctggcggg ctccccgccg tcggtgcaga
    39361 ccgaggagga ggcggcggag atggtggagg cgcaggcccc gacgccgaag ttctgacgcc
    39421 gcggtcgcaa gcacacgccg acgggcggtg gggttcggtg cgaaccccac cgcccgtcgg
    39481 cgtgtcaggc gtttctcagc ggtgtgtcac aggcgctgcc acagggcggg gacgttcggc
    39541 ggctcccagc cggggtaggc ggtgtggccc tggatgcacc ggtagctgac gccgttgtag
    39601 ctcaccacgt caccggccgc gtaggtggct cccagctgcc aggtggtctc accgccgtcg
    39661 tcgccggaca cggtgagggt gtacgtggtg gtgtgggtga cggtgcccgc acccgtgagg
    39721 gtcagggtgt aggtgccgcc ggccgtgccc gcggcgacct ggaccgtggc ggtcgaggac
    39781 tggccggagg tgaccgagtc cgggctgaag ccgacgctca caccggtcgg agcgccggac
    39841 gccgacagcc gcacgctctg cgcgtcgccg ctggtcgtgg cggtgttcac ggtgacggac
    39901 gcggagctgc ccgggtcgac ggtgcccgag gacgggttcg cggagatcga gaagtcgtcc
    39961 tgcgggttcg gtgcgtctcc gacggcggtc ttccagatcg tgtacgcgat gccgtcggcg
    40021 ctgcggttca gcgcggtggc gctgatgttg gcggtggtgt cgcaggcgga gtggtagcac
    40081 gggtcgtagg agcggccggc ggtgccgccc cacttggcgg cctccgtgga cgacttgatc
    40141 gcggaggcgc cggtggcgta gcccgaggtg gggatgccga cctgctggaa ggagtagtcg
    40201 tcggagcggc cctggccctc gacgttctcc tgcggggcga ggccgaggga ggtccagtac
    40261 tcccgcatcg gggcggaggc cgaggaggac aggttgttga tgaagtagcc gccgttgacg
    40321 gaggcgacca tgtcgaagtt gtagtacgcc ttgatccggg agcggtcggt ggtggagagg
    40381 ttccgggcgt agaagtcgga gccgttcagg ccctgctcct cgtcggtcca ccaggcgaac
    40441 cggacgcggt tgtccatggt cgggttctgc tcggccaggg tgagcgccgt ctcgaggagc
    40501 gcggcggaac cggaaccgtt gtcgttgatg ccggggccgg ccgagacgcc gtcgaggtgg
    40561 gcgccgaaca tgtagacgct gttcgcgtcg cccttcggcc actcggcgat caggttgttg
    40621 cccgcgccgg cggagcagcc ggaggtgcag gtctgctcgg tgacggtgta gccggccgcc
    40681 tggagcttgc ccttcacgta cgcgagtgag gcgtcgtacc cggagccggt ggaccggcgg
    40741 ttgccgccgt tctgcgcggc gatggaaccg aactgggcca ggtgggcctg gacctgggcg
    40801 acgtcgacgt cgggcggcgt gccggggttg ttgccgccgc cgacggtgag ggtgtactgg
    40861 gcggtgtggc tcttgctgcc cgccgtgccc ttgaccgtga gcgagtaggt tccggcggcg
    40921 gtgcccgagg tggtggagac gcgcatcgtc gagctggagc cggaggtgac cgtggacggg
    40981 ctgaaggaga cgctgacgcc gggcggggtg ccggtggcgg tcagcgacac ctgctgggcg
    41041 ctgccggtga cggtggtggt gttgaccgtg gcgttgaccg cggacccggc ctcgacgttg
    41101 ccgctcgccg ggctgagggc cagcg
//
