LOCUS       NC_003888              10216 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    RefSeq; complete genome.
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces
            albidoflavus group.
REFERENCE   1  (bases 1 to 8667507)
  AUTHORS   Hsiao,N.H. and Kirby,R.
  TITLE     Comparative genomics of Streptomyces avermitilis, Streptomyces
            cattleya, Streptomyces maritimus and Kitasatospora aureofaciens
            using a Streptomyces coelicolor microarray system
  JOURNAL   Antonie Van Leeuwenhoek 93 (1-2), 1-25 (2008)
   PUBMED   17588127
REFERENCE   2  (bases 1 to 8667507)
  AUTHORS   Bentley,S.D., Chater,K.F., Cerdeno-Tarraga,A.M., Challis,G.L.,
            Thomson,N.R., James,K.D., Harris,D.E., Quail,M.A., Kieser,H.,
            Harper,D., Bateman,A., Brown,S., Chandra,G., Chen,C.W., Collins,M.,
            Cronin,A., Fraser,A., Goble,A., Hidalgo,J., Hornsby,T., Howarth,S.,
            Huang,C.H., Kieser,T., Larke,L., Murphy,L., Oliver,K., O'Neil,S.,
            Rabbinowitsch,E., Rajandream,M.A., Rutherford,K., Rutter,S.,
            Seeger,K., Saunders,D., Sharp,S., Squares,R., Squares,S., Taylor,K.,
            Warren,T., Wietzorrek,A., Woodward,J., Barrell,B.G., Parkhill,J. and
            Hopwood,D.A.
  TITLE     Complete genome sequence of the model actinomycete Streptomyces
            coelicolor A3(2)
  JOURNAL   Nature 417 (6885), 141-147 (2002)
   PUBMED   12000953
REFERENCE   3  (bases 1 to 8667507)
  AUTHORS   Redenbach,M., Kieser,H.M., Denapaite,D., Eichner,A., Cullum,J.,
            Kinashi,H. and Hopwood,D.A.
  TITLE     A set of ordered cosmids and a detailed genetic and physical map for
            the 8 Mb Streptomyces coelicolor A3(2) chromosome
  JOURNAL   Mol. Microbiol. 21 (1), 77-96 (1996)
   PUBMED   8843436
REFERENCE   4  (bases 1 to 8667507)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2002) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
  REMARK    Direct Submission
REFERENCE   5  (bases 1 to 8667507)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2002) Sanger Institute, Wellcome Trust Genome
            Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
  REMARK    Direct Submission
COMMENT     ##antiSMASH-Data-START##
            Version     :: 8.0.1
            Run date    :: 2025-05-26 12:13:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start :: 791583
            Orig. end   :: 801799
            ##antiSMASH-Data-END##
            REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10216
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="6"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10216
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10216
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5216](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5216
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(118..297)
                     /db_xref="GeneID:1096173"
                     /gene_synonym="SCF81.09c"
                     /locus_tag="SCO0750"
     CDS             complement(118..297)
                     /codon_start=1
                     /db_xref="GeneID:1096173"
                     /gene_synonym="SCF81.09c"
                     /locus_tag="SCO0750"
                     /note="SCF81.09c, unknown, len: 59 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_625053.1"
                     /transl_table=11
                     /translation="MTTDTDGKPAVRRLETGWSKARRLRSRGVMRTCVPAVEDGSTVRA
                     PQSGQESNIVRGED"
     regulatory      complement(308..312)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(398..2884)
                     /db_xref="GeneID:1096174"
                     /gene_synonym="SCF81.10c"
                     /locus_tag="SCO0751"
     CDS             complement(398..2884)
                     /codon_start=1
                     /db_xref="GeneID:1096174"
                     /gene_synonym="SCF81.10c"
                     /locus_tag="SCO0751"
                     /note="SCF81.10c, possible regulatory protein, len: 894 aa;
                     similar to TR:Q9ZBJ0 (EMBL:AL035161) Streptomyces
                     coelicolor conserved hypothetical protein SC9C7.20, 860 aa;
                     fasta scores: opt: 663 z-score: 716.6 E(): 1.5e-32; 29.6%
                     identity in 873 aa overlap and to TR:CAB44394
                     (EMBL:AL078610) Streptomyces coelicolor regulatory protein
                     SCH35.33c, 422 aa; fasta scores: opt: 305 z-score: 312.4
                     E(): 5e-10; 33.3% identity in 258 aa overlap. Contains
                     match to Pfam entry PF01590 GAF, GAF domain"
                     /product="regulatory protein"
                     /protein_id="NP_625054.1"
                     /transl_table=11
                     /translation="MPHKRCNGEVAGEDAAERGPRTLRAEGALNAIVAGPVPQERLRVI
                     LEQALVFAGASFAALYAPGDDRELLCLVESAGVPRSLYGVRDSYPASGGSPVADAHRAG
                     EAVWIGPEEFAGSAESRHVPSSGFSLAVLPVRGDGGGCLLALTERPDGFDTDDRTCLEA
                     IAEAMTCPAPAETAARAETGDLQPDAFTLTMDSGRVEVGDGILRLFGLAPGEFDGKVET
                     LLGLTVPEDLPSLMSVTESDHMTIGERELEFRVLQPTGPPKWLRLSGRLLPGGEGRPAL
                     LVGTVADASTLRPDVTDVARVQRLAAALATAGTVRDVSQAVVAALRRPLRADRIALAEL
                     ENDRLVVTVLDPPDPESWPELWRLEWRTEWPDAPVRAMPTLAAALREGRARIWPAGTGD
                     LEPALADVGPGGLAVLPLPAGGRMAGACLIGWDTPHDFGPDERALLTASAGLAGQALMR
                     AHAFDAEHELVGMLQRQLLPRRLPKLPGAVAVARYLPSTAGLELGGDWYDVIPLPDHHV
                     ALVIGDVQGHSAGAATLMGQMRTALRAYAVEGHPPDVVVSHANRLLTGMETDLFATCVY
                     VDLDMEEGSAWCVRAGHLPPVLRHPDGSTEIAEVEGGPPLGVVTQADFPMSPLRLRPGT
                     LIALTTDGLVETPESDIDEGMDRFAHALAVSAPDHLGLVADALLGNARRNDDVALLLVR
                     YDGMALRPLRESWSVWRLPEAVRHARRFTRRTLRTWGVPDDDIDGVLLIVSELVTNALV
                     HTDGKVRLDLTLIGGRLRVAVADASPRTPVKPTSIGWEATGGRGILLVEAMSATWGTLP
                     VSGGKQVWSEIPVGGG"
     PFAM_domain     complement(470..757)
                     /aSDomain="HATPase_c_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13581.9"
                     /description="Histidine kinase-like ATPase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0751_0201"
                     /evalue="2.80E-11"
                     /label="SCO0751"
                     /locus_tag="SCO0751"
                     /protein_end="805"
                     /protein_start="709"
                     /score="43.5"
                     /tool="antismash"
                     /translation="WRLPEAVRHARRFTRRTLRTWGVPDDDIDGVLLIVSELVTNALVH
                     TDGKVRLDLTLIGGRLRVAVADASPRTPVKPTSIGWEATGGRGILLVEAMS"
     PFAM_domain     complement(800..1348)
                     /aSDomain="SpoIIE"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07228.15"
                     /description="Stage II sporulation protein E (SpoIIE)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0751_0200"
                     /evalue="1.20E-46"
                     /label="SCO0751"
                     /locus_tag="SCO0751"
                     /protein_end="695"
                     /protein_start="512"
                     /score="159.3"
                     /tool="antismash"
                     /translation="PDHHVALVIGDVQGHSAGAATLMGQMRTALRAYAVEGHPPDVVVS
                     HANRLLTGMETDLFATCVYVDLDMEEGSAWCVRAGHLPPVLRHPDGSTEIAEVEGGPPL
                     GVVTQADFPMSPLRLRPGTLIALTTDGLVETPESDIDEGMDRFAHALAVSAPDHLGLVA
                     DALLGNARRNDDVALLLVRY"
     misc_feature    complement(1502..1945)
                     /gene_synonym="SCF81.10c"
                     /locus_tag="SCO0751"
                     /note="Pfam match to entry PF01590 GAF, GAF domain, score
                     27.40, E-value 0.00034"
     PFAM_domain     complement(2027..2287)
                     /aSDomain="PAS_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08447.15"
                     /db_xref="GO:0005515"
                     /description="PAS fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0751_0199"
                     /evalue="2.10E-08"
                     /gene_ontologies="GO:0005515: protein binding"
                     /label="SCO0751"
                     /locus_tag="SCO0751"
                     /protein_end="286"
                     /protein_start="199"
                     /score="34.5"
                     /tool="antismash"
                     /translation="EVGDGILRLFGLAPGEFDGKVETLLGLTVPEDLPSLMSVTESDHM
                     TIGERELEFRVLQPTGPPKWLRLSGRLLPGGEGRPALLVGTV"
     PFAM_domain     complement(2384..2770)
                     /aSDomain="GAF_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13185.9"
                     /db_xref="GO:0005515"
                     /description="GAF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0751_0198"
                     /evalue="3.40E-07"
                     /gene_ontologies="GO:0005515: protein binding"
                     /label="SCO0751"
                     /locus_tag="SCO0751"
                     /protein_end="167"
                     /protein_start="38"
                     /score="30.7"
                     /tool="antismash"
                     /translation="QERLRVILEQALVFAGASFAALYAPGDDRELLCLVESAGVPRSLY
                     GVRDSYPASGGSPVADAHRAGEAVWIGPEEFAGSAESRHVPSSGFSLAVLPVRGDGGGC
                     LLALTERPDGFDTDDRTCLEAIAEA"
     gene            complement(3106..4419)
                     /db_xref="GeneID:1096175"
                     /gene_synonym="salO; SCF81.11c"
                     /locus_tag="SCO0752"
     CDS             complement(3106..4419)
                     /codon_start=1
                     /db_xref="GeneID:1096175"
                     /gene_synonym="salO; SCF81.11c"
                     /locus_tag="SCO0752"
                     /note="SCF81.11c, salO, protease precursor, len: 437 aa;
                     highly similar to but longer than TR:Q54395 (EMBL:D50081)
                     Streptomyces lividans, SalO precursor, 354 aa; fasta
                     scores: opt: 1713 z-score: 1480.6 E(): 0; 89.1% identity in
                     367 aa overlap, to SW:PRTD_STRGR (EMBL:L29019) Streptomyces
                     griseus serine protease D precursor (EC 3.4.21.-) SgpD, 392
                     aa; fasta scores: opt: 1097 z-score: 952.8 E(): 0; 53.4%
                     identity in 363 aa overlap and to Streptomyces coelicolor
                     StI11.30c, 360 aa; fasta scores: opt: 1093 z-score: 833.4
                     E(): 0; 52.8% identity in 362 aa overlap. Contains match to
                     Pfam entry PF00089 trypsin, Trypsin and two matches to
                     Prosite entry PS00134 Serine proteases, trypsin family,
                     histidine active site. Contains also possible N-terminal
                     signal sequence peptide and degenerate repeat x6
                     GGA(G/D)AG"
                     /product="protease"
                     /protein_id="NP_625055.1"
                     /transl_table=11
                     /translation="MSHKRIPKRRAAMAAGGVVALGAAAILLPNANASQDGGSSDDAAA
                     APRTLKAADASDLAARLAGLLGDSFAGSYYDSGARQLVVNVVPGDNNQVVVQAEKAGAK
                     VREVDNSMGELRGGAQTLKAEAGIPGTAWAIDPRTNKILVTADSTVTGDRWDRLESTVD
                     GLGSGMATVRKSAGTFKTFASGGDAIFGGGARCSLGFNVTAGDGSPAFLTAGHCGVAAD
                     QWSDAQGGQPIATVDQAVFPGEGDFALVRYDDPATEAPSEVDLGDQTLPISGAAEAAVG
                     QEVFRMGSTTGLADGQVLGLDATVNYPEGMVTGLIQTDVCAEPGDSGGSLFTRDGLAIG
                     LTSGGSGDCTVGGETFFQPVTTALAAVGATLGGEDGGAGAGDAGGAGAGAGEEGDAGGA
                     GDAGDGGAGAGDKGDTGDAGDAGDGAPVGAGDGSGLTG"
     repeat_region   complement(3118..3306)
                     /gene_synonym="salO; SCF81.11c"
                     /locus_tag="SCO0752"
                     /note="Degenerate repeat x6 GGA(G/D)AG"
     misc_feature    complement(3319..3873)
                     /gene_synonym="salO; SCF81.11c"
                     /locus_tag="SCO0752"
                     /note="Pfam match to entry PF00089 trypsin, Trypsin, score
                     80.60, E-value 9.7e-25"
     PFAM_domain     complement(3328..3789)
                     /aSDomain="Trypsin"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00089.29"
                     /db_xref="GO:0004252"
                     /db_xref="GO:0006508"
                     /description="Trypsin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0752_0203"
                     /evalue="4.40E-14"
                     /gene_ontologies="GO:0004252: serine-type endopeptidase
                     activity"
                     /gene_ontologies="GO:0006508: proteolysis"
                     /label="SCO0752"
                     /locus_tag="SCO0752"
                     /protein_end="364"
                     /protein_start="210"
                     /score="53.0"
                     /tool="antismash"
                     /translation="FLTAGHCGVAADQWSDAQGGQPIATVDQAVFPGEGDFALVRYDDP
                     ATEAPSEVDLGDQTLPISGAAEAAVGQEVFRMGSTTGLADGQVLGLDATVNYPEGMVTG
                     LIQTDVCAEPGDSGGSLFTRDGLAIGLTSGGSGDCTVGGETFFQPVTTAL"
     misc_feature    complement(3424..3459)
                     /gene_synonym="salO; SCF81.11c"
                     /locus_tag="SCO0752"
                     /note="PS00135 Serine proteases, trypsin family, serine
                     active site"
     misc_feature    complement(3769..3786)
                     /gene_synonym="salO; SCF81.11c"
                     /locus_tag="SCO0752"
                     /note="PS00134 Serine proteases, trypsin family, histidine
                     active site"
     PFAM_domain     complement(3928..4092)
                     /aSDomain="Pro_Al_protease"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02983.17"
                     /db_xref="GO:0005576"
                     /db_xref="GO:0006508"
                     /db_xref="GO:0008236"
                     /description="Alpha-lytic protease prodomain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0752_0202"
                     /evalue="3.70E-14"
                     /gene_ontologies="GO:0005576: extracellular region"
                     /gene_ontologies="GO:0006508: proteolysis"
                     /gene_ontologies="GO:0008236: serine-type peptidase
                     activity"
                     /label="SCO0752"
                     /locus_tag="SCO0752"
                     /protein_end="164"
                     /protein_start="109"
                     /score="52.7"
                     /tool="antismash"
                     /translation="NSMGELRGGAQTLKAEAGIPGTAWAIDPRTNKILVTADSTVTGDR
                     WDRLESTVDG"
     regulatory      complement(4429..4434)
                     /regulatory_class="ribosome_binding_site"
     gene            5001..5216
                     /db_xref="GeneID:1096176"
                     /gene_synonym="SCF81.12"
                     /locus_tag="SCO0753"
     CDS             5001..5216
                     /codon_start=1
                     /db_xref="GeneID:1096176"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /gene_synonym="SCF81.12"
                     /locus_tag="SCO0753"
                     /note="SCF81.12, unknown, len: 71 aa"
                     /product="hypothetical protein"
                     /protein_id="NP_625056.1"
                     /sec_met_domain="strepbact (E-value: 2.4e-37, bitscore:
                     126.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTPQVETVEISDADLDNVSGGLNVNAVGTVTGLVDGIAPVSGL
                     LNTAVGTVEGVTGLNTAPVTGLVAGL"
     regulatory      5378..5381
                     /regulatory_class="ribosome_binding_site"
     gene            5394..6140
                     /db_xref="GeneID:1096177"
                     /gene_synonym="SCF81.13"
                     /locus_tag="SCO0754"
     CDS             5394..6140
                     /codon_start=1
                     /db_xref="GeneID:1096177"
                     /gene_synonym="SCF81.13"
                     /locus_tag="SCO0754"
                     /note="SCF81.13, hypothetical protein, len: 268 aa.
                     Contains possible N-teminal signal sequence peptide"
                     /product="hypothetical protein"
                     /protein_id="NP_625057.1"
                     /transl_table=11
                     /translation="MRFARPQGWLVLSVTLIAMAAASVWAVGGSVTSTVSAPAVLTHGQ
                     GSYLLQSPVSGQVTAVLARPGQRLAADAPVLKVRTAKGETVVRTVDAGRVSALAATVGQ
                     IIATGANVASVEKVAHAGDPLYATVYVPAENAAAIPAHASVDLTVQSVPTQQYGVLHGE
                     VKSVDRSAQSAQTIGAFLGDSALGEQFTEDGRPVAVTVRLATSKSTKSGYAWSSADGPP
                     FELTSMTLASGSIRLADQRPVDWLLP"
     PFAM_domain     5652..5912
                     /aSDomain="HlyD_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13437.9"
                     /description="HlyD family secretion protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0754_0204"
                     /evalue="6.90E-08"
                     /label="SCO0754"
                     /locus_tag="SCO0754"
                     /protein_end="173"
                     /protein_start="86"
                     /score="33.2"
                     /tool="antismash"
                     /translation="VRTVDAGRVSALAATVGQIIATGANVASVEKVAHAGDPLYATVYV
                     PAENAAAIPAHASVDLTVQSVPTQQYGVLHGEVKSVDRSAQS"
     gene            6137..8359
                     /db_xref="GeneID:1096178"
                     /gene_synonym="SCF81.14"
                     /locus_tag="SCO0755"
     CDS             6137..8359
                     /codon_start=1
                     /db_xref="GeneID:1096178"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /gene_synonym="SCF81.14"
                     /locus_tag="SCO0755"
                     /note="SCF81.14, possible ABC transporter, len: 740 aa;
                     similar to SW: COMA_STRPN (EMBL:M36180) Streptococcus
                     pneumoniae transport ATP-binding protein ComA, 717 aa;
                     fasta scores: opt: 1035 z-score: 1141.5 E(): 0; 29.1%
                     identity in 721 aa overlap. Contains two matches to Pfam
                     entries PF00664 ABC_membrane, ABC transporter transmembrane
                     region and PF00005 ABC_tran, ABC transporter and two to
                     Prosite entries PS00017 ATP/GTP-binding site motif A
                     (P-loop) and PS00211 ABC transporters family signature"
                     /product="ABC transporter"
                     /protein_id="NP_625058.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.2e-39, bitscore:
                     133.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAQETRGRRRAAPPRRSVPKSRARTVRTPTVLQMEAVECGAAS
                     LAMVLGHYGRHVPLEELRIACGVSRDGSRASNLLKAARSYGFTAKGMQMDLAALAEVTA
                     PAILFWEFNHYVVYDGMGRRFGRRGVFINDPGKGRRFVSLEDFDGSFTGVVLTMEPGDG
                     FTRGGRKPGVLGAMPARLRGTAGTLPAAVLASLLLVAVGAAVPALSRTYIDMFLIGGQT
                     SLLGVLFASMGACVLLTVVLTWLQQANLLHGRIISSTLSSARFLRHLLRLPVTFFSQRS
                     PADLVQRLQSNDAVAETLARDLAAAGVDAIVVVLYAVLLYTYDPQLTFVGIGVALLNIL
                     AMRVVIRLRATRTAKLRADTARLTNTAYTGLQLIETMKATGGEDGYFRKWAGQHATTLE
                     EQQRLGVPSAWLGVVAPTLATLNSGLILWIGGMRAVEGHISVGLLVAFQALVVRFTAPL
                     TRLNGVAGRIQDFAADVARLKDVENFRADPLYDRPGDGDSTRRLRGHVELQNVSFGYNP
                     LDKPLLSGFDLTVGPGQQVALVGGSGSGKSTVSRLISGLYASWDGVIRIDGQRLDDIPR
                     GALASSVSFVDQDVFLFEGSVRDNVALWDPSIPDDAVVEALKDAALYDVVTRRPGGLHS
                     PVEQDGRNFSGGQRQRLEIARALVRRPSILVLDEVTSALDAETELVVMDNLRRRGCACV
                     VIAHRLSTVRDSDEIVVLDHGTVVERGRHEELLARGGAYAALVRER"
     aSDomain        6221..8350
                     /aSDomain="TIGR03796"
                     /aSTool="tigrfam"
                     /description="NHLM_micro_ABC1: NHLM bacteriocin system ABC
                     transporter, peptidase/ATP-binding protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO0755_0018"
                     /evalue="0.00E+00"
                     /identifier="TIGR03796"
                     /label="SCO0755"
                     /locus_tag="SCO0755"
                     /protein_end="738"
                     /protein_start="28"
                     /score="1028.4"
                     /tool="antismash"
                     /translation="RTPTVLQMEAVECGAASLAMVLGHYGRHVPLEELRIACGVSRDGS
                     RASNLLKAARSYGFTAKGMQMDLAALAEVTAPAILFWEFNHYVVYDGMGRRFGRRGVFI
                     NDPGKGRRFVSLEDFDGSFTGVVLTMEPGDGFTRGGRKPGVLGAMPARLRGTAGTLPAA
                     VLASLLLVAVGAAVPALSRTYIDMFLIGGQTSLLGVLFASMGACVLLTVVLTWLQQANL
                     LHGRIISSTLSSARFLRHLLRLPVTFFSQRSPADLVQRLQSNDAVAETLARDLAAAGVD
                     AIVVVLYAVLLYTYDPQLTFVGIGVALLNILAMRVVIRLRATRTAKLRADTARLTNTAY
                     TGLQLIETMKATGGEDGYFRKWAGQHATTLEEQQRLGVPSAWLGVVAPTLATLNSGLIL
                     WIGGMRAVEGHISVGLLVAFQALVVRFTAPLTRLNGVAGRIQDFAADVARLKDVENFRA
                     DPLYDRPGDGDSTRRLRGHVELQNVSFGYNPLDKPLLSGFDLTVGPGQQVALVGGSGSG
                     KSTVSRLISGLYASWDGVIRIDGQRLDDIPRGALASSVSFVDQDVFLFEGSVRDNVALW
                     DPSIPDDAVVEALKDAALYDVVTRRPGGLHSPVEQDGRNFSGGQRQRLEIARALVRRPS
                     ILVLDEVTSALDAETELVVMDNLRRRGCACVVIAHRLSTVRDSDEIVVLDHGTVVERGR
                     HEELLARGGAYAALVR"
     PFAM_domain     6224..6619
                     /aSDomain="Peptidase_C39"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03412.18"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0006508"
                     /db_xref="GO:0008233"
                     /db_xref="GO:0016020"
                     /description="Peptidase C39 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0755_0205"
                     /evalue="5.60E-39"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0006508: proteolysis"
                     /gene_ontologies="GO:0008233: peptidase activity"
                     /gene_ontologies="GO:0016020: membrane"
                     /label="SCO0755"
                     /locus_tag="SCO0755"
                     /protein_end="161"
                     /protein_start="29"
                     /score="133.1"
                     /tool="antismash"
                     /translation="TPTVLQMEAVECGAASLAMVLGHYGRHVPLEELRIACGVSRDGSR
                     ASNLLKAARSYGFTAKGMQMDLAALAEVTAPAILFWEFNHYVVYDGMGRRFGRRGVFIN
                     DPGKGRRFVSLEDFDGSFTGVVLTMEPG"
     misc_feature    6698..7510
                     /gene_synonym="SCF81.14"
                     /locus_tag="SCO0755"
                     /note="Pfam match to entry PF00664 ABC_membrane, ABC
                     transporter transmembrane region., score 36.10, E-value
                     8e-07"
     PFAM_domain     6707..7507
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00664.26"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0016020"
                     /db_xref="GO:0055085"
                     /db_xref="GO:0140359"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0755_0206"
                     /evalue="7.30E-24"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0016020: membrane"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /gene_ontologies="GO:0140359: ABC-type transporter
                     activity"
                     /label="SCO0755"
                     /locus_tag="SCO0755"
                     /protein_end="457"
                     /protein_start="190"
                     /score="85.0"
                     /tool="antismash"
                     /translation="AVLASLLLVAVGAAVPALSRTYIDMFLIGGQTSLLGVLFASMGAC
                     VLLTVVLTWLQQANLLHGRIISSTLSSARFLRHLLRLPVTFFSQRSPADLVQRLQSNDA
                     VAETLARDLAAAGVDAIVVVLYAVLLYTYDPQLTFVGIGVALLNILAMRVVIRLRATRT
                     AKLRADTARLTNTAYTGLQLIETMKATGGEDGYFRKWAGQHATTLEEQQRLGVPSAWLG
                     VVAPTLATLNSGLILWIGGMRAVEGHISVGLLVAFQALVVRFTAP"
     PFAM_domain     7706..8152
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00005.30"
                     /db_xref="GO:0005524"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0755_0207"
                     /evalue="2.30E-28"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /label="SCO0755"
                     /locus_tag="SCO0755"
                     /protein_end="672"
                     /protein_start="523"
                     /score="99.5"
                     /tool="antismash"
                     /translation="SGFDLTVGPGQQVALVGGSGSGKSTVSRLISGLYASWDGVIRIDG
                     QRLDDIPRGALASSVSFVDQDVFLFEGSVRDNVALWDPSIPDDAVVEALKDAALYDVVT
                     RRPGGLHSPVEQDGRNFSGGQRQRLEIARALVRRPSILVLDEVTS"
     misc_feature    7733..8281
                     /gene_synonym="SCF81.14"
                     /locus_tag="SCO0755"
                     /note="Pfam match to entry PF00005 ABC_tran, ABC
                     transporter, score 178.40, E-value 1.2e-49"
     misc_feature    7754..7777
                     /gene_synonym="SCF81.14"
                     /locus_tag="SCO0755"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
     misc_feature    8066..8110
                     /gene_synonym="SCF81.14"
                     /locus_tag="SCO0755"
                     /note="PS00211 ABC transporters family signature"
     regulatory      8350..8353
                     /gene_synonym="SCF81.14"
                     /locus_tag="SCO0755"
                     /regulatory_class="ribosome_binding_site"
ORIGIN
        1 gcgggacccc tgtgacgcta ccggcgtgcc cctcgcggtc cgcggccgcc ccgcaacgcg
       61 caccgcgccg gcaccaaggc cggcgcgctg ggcggtgtca ccaccctcgg ggtccggtca
      121 gtcctcgccc cggacgatgt tcgactcctg acccgattgc ggtgcgcgga cggtgctgcc
      181 gtcctccacg gcgggtacgc aggtgcgcat cacgcctctg ctccgcaggc ggcgggcctt
      241 cgaccagcct gtctccagcc gccggacggc gggtttgccg tcggtgtccg tggtcacggg
      301 gcatcatctt ccttctggtt ccgcttctgg tgcgctcgcc cctgcgggtc cccggacggg
      361 gaccggtgaa acccaggggc cgtgcgggcc gcgcggctca gccgccgccc accgggatct
      421 cgctccacac ctgcttgccc ccgctgaccg gcagcgtccc ccaggtcgcc gacatcgcct
      481 cgaccaggag gatgccgcgt ccgccggtgg cctcccagcc gatgctggtc ggcttgaccg
      541 gcgtgcgcgg cgaggcgtcg gcgacggcca cgcgcagccg tccgccgatc agggtgaggt
      601 cgagccgtac cttgccgtcg gtgtgcacca gggcgttggt gaccagctcg gagacgatca
      661 ggagcactcc gtcgatgtcg tcgtccggta cgccccaggt gcgcagggtg cgccgggtga
      721 agcggcgggc gtgccgcacg gcctcgggca gccgccacac cgaccagctc tcgcgcagcg
      781 ggcgcagggc cattccgtcg tagcgcacca gcagcagggc cacgtcgtcg ttgcggcggg
      841 cgttgccgag cagggcgtcg gcgacgagtc cgaggtggtc gggggcggag acggccagcg
      901 cgtgcgcgaa ccggtccatg ccctcgtcga tgtcggactc cggcgtctcc accaggccgt
      961 ccgtggtgag ggcgatcagc gtgccgggcc gcagccgcag cgggctcatc gggaagtcgg
     1021 cctgggtcac cacgccgagc ggcgggccgc cctccacctc cgcgatctcg gtgctgccgt
     1081 cgggatggcg cagcaccggt ggcaggtgcc ccgcgcgcac gcaccaggcg gagccctcct
     1141 ccatgtcgag gtcgacgtag acgcaggtgg cgaagaggtc ggtctccatg cccgtcagca
     1201 gccggttggc gtgggagacc acgacgtccg gcgggtggcc ctcgaccgcg taggcgcgca
     1261 gggcggtgcg catctggccc atgagggtgg ccgcgccggc gctgtggccc tggacgtcgc
     1321 cgatgacgag ggcgacgtgg tggtcgggca gcgggatcac gtcgtaccag tcgccgccca
     1381 gctccaggcc cgccgtgctg ggcaggtagc gggcgacggc gaccgcgccg ggcagcttgg
     1441 gcaggcggcg cggcagcagc tggcgctgga gcatgccgac cagctcgtgc tcggcgtcga
     1501 aggcgtgggc gcgcatcagg gcctgcccgg ccaggcccgc ggaggcggtg agcagggccc
     1561 gttcgtcggg gccgaagtcg tgcggggtgt cccagccgat caggcaggca ccggccatgc
     1621 gtccgccggc gggcagcggc agcacggcga ggccgccggg gccgacgtcg gcgagggcgg
     1681 gctccaggtc cccggtgccg gcgggccaga tccgggcgcg gccctcgcgc agcgcggcgg
     1741 ccagggtcgg catggcccgt accggcgcgt ccggccactc ggtgcgccac tccaggcgcc
     1801 acagttcggg ccaggactcg gggtcgggcg ggtcgaggac ggtgacgacg agccggtcgt
     1861 tctccagctc ggccagcgcg atccggtcgg cccgcagcgg cctgcgcagg gcggcgacga
     1921 cggcctggct gacgtcgcgg accgtcccgg cggtggcgag cgcggcggcc agccgctgga
     1981 cgcgggcgac gtcggtcacg tccggacgca gggtggaggc gtcggcgacg gtgccgacca
     2041 gaagggccgg ccggccctcg ccgccgggca gcaggcgccc gctgagccgc agccacttcg
     2101 gcgggccggt gggctggagc acccggaact ccagctcgcg ctcgccgatg gtcatgtggt
     2161 cggactcggt caccgacatc agggacggca ggtcctccgg cacggtgagg ccgagcagcg
     2221 tctcgacctt gccgtcgaac tcgccggggg ccagtccgaa cagccgcagg atgccgtcgc
     2281 cgacctccac ccggccggag tccatggtca gggtgaaggc gtccggctgg aggtcaccgg
     2341 tctcggcacg ggcggcggtc tcggccgggg cggggcaggt catcgcctcc gcgatcgcct
     2401 ccaggcacgt acggtcgtcg gtgtcgaacc cgtccgggcg ctcggtcagg gcgagaaggc
     2461 agccgccgcc gtccccgcgc acgggcagga cggcgagcga gaagccgctc gacggcacat
     2521 gccgtgactc cgccgatccg gcgaactcct ccggcccgat ccacaccgcc tcgccggcgc
     2581 ggtgggcgtc ggcgaccggg gaaccgccgg acgcggggta gctgtcgcgt acgccgtaca
     2641 gggagcgggg cactccggcc gactcgacca ggcagagcag ctcgcgatcg tcgcccggcg
     2701 cgtagagcgc ggcgaaggag gcgcccgcga agaccagcgc ctgctcgagg attacgcgca
     2761 gccgctcctg cggcaccggt ccggccacga tcgcgttcag ggcgccctcg gcacgcagcg
     2821 tcctcggtcc gcgttccgca gcgtcctctc cggccacctc gccattacag cgcttgtgag
     2881 gcatccgcgc agcccctggg gaccggggag cggcgatcag gggcactccg gggctcgcgg
     2941 acgggcgctt cgcgcctccg gacgggtgcg ggccgggccg ggacctgccg gcggccagga
     3001 ggtggtggcg gacacgcacc gctgcccgcg ggccgtgaac cagtgcggcg ggcggtgcgg
     3061 ccggggcgca gaccggccgc accgagccga cgtggcgtca gcccgtcagc ccgtcagccc
     3121 cgagccgtcc ccagcgccga cgggtgcacc gtcacccgcg tcacccgcgt cacctgtgtc
     3181 acctttgtca cccgcaccag cgccgccgtc gcccgcgtcg cccgcacctc ccgcatcacc
     3241 ctcctcgccg gcacctgcgc cggcaccgcc cgcgtctccg gcacccgcgc cgccgtcctc
     3301 gcccccgagg gtggcgccga ccgccgccag ggccgtggtg accggctgga agaaggtctc
     3361 gccgccgacg gtgcagtcac cgctgccgcc ggaggtcagg ccgatcgcga ggccgtcccg
     3421 cgtgaagagg gagccgccgc tgtcgccggg ctcggcgcag acgtcggtct gtatgaggcc
     3481 ggtgaccatg ccctcgggat agttgacggt ggcgtccagg ccgagcacct gcccgtcggc
     3541 cagtccggtc gtactgccca tgcggaagac ctcctggccg accgccgcct cggcggcccc
     3601 gctgatcggc agggtctggt cgccgaggtc gacctcgctc ggcgcctcgg tcgccgggtc
     3661 gtcgtacctg acgagcgcga agtcgccctc gccggggaag accgcctggt cgacggtggc
     3721 gatcggctgt ccgccctgtg cgtcggacca ctggtcggcc gccaccccgc agtgaccggc
     3781 cgtcaggaag gcgggcgagc cgtcgcccgc ggtgacgttg aacccgagtg agcagcgcgc
     3841 tccgccgccg aagatcgcgt cgccgcccga cgcgaaggtc ttgaaggtgc cggcggactt
     3901 cctgaccgtc gccatgccgg acccgaggcc gtcgacggtg gactccagcc ggtcccaccg
     3961 gtcgccggtg acggtgctgt cggcggtcac caggatcttg ttggtccgcg ggtcgatcgc
     4021 ccacgcggtc ccggggatgc cggcctcggc cttcagggtc tgcgcgccgc cgcgcagctc
     4081 gcccatgctg ttgtcgacct cgcggacctt cgcacccgcc ttctcggcct gcacgaccac
     4141 ctggttgttg tcgccgggga cgacgttgac gaccagttgc cgggcgccgg agtcgtagta
     4201 ggagccggcg aagctgtcgc cgagcaggcc ggcgagccgg gcggcgaggt ccgacgcgtc
     4261 cgccgccttg agcgtcctgg gtgccgcggc ggcatcgtcc gaggagccgc cgtcctgcga
     4321 ggcgttcgcg ttcggcagca ggatcgcggc cgcgccgagc gccaccacac cgcccgccgc
     4381 catcgcggcc ctgcgcttgg ggattcgctt gtgactcaac ctgctcgacc tcctgggacc
     4441 ggggttgatg cccgccggtc cggcagctgt tgggggcgcc tggacggctg ttggtacgca
     4501 cggaccgggc ggggtgttca gccgggccct cgcgccgccc ccgatcggca ccctccgcat
     4561 ccggagcgcg acgcaccgtt gcgatcacgg agcggaatga ctgcttcagc gaatctgcac
     4621 atcgaatgcc caacccggtc actcccgttg gcgcatctgc acaagcccgc ggcggcccgt
     4681 acgcctttgg ggccgtagtg ccccaatcgc ctcggccggg gcaaggggcc gcacgagccg
     4741 atctcgcgca ccgtgtgaag aagtggccgc gaaggagtgc gcgcccctgc acgcttgggc
     4801 ccgcaggcct cgcaagtgtg ctggtgagag gggtgtttga ttggaagccc ggaccggccg
     4861 cgtgctttga tccatcgcac cgcgggggcc gcggagggct ccggaaaagg gcgcccggcg
     4921 cccgcggtcg cggccgtcat ctgtccccag agggggccgc tccccccttg tgaaatggct
     4981 atacgaaggg aagttccatc atgaactcca ccccccaggt tgagaccgtc gagatctccg
     5041 acgccgacct cgacaacgtc tccggcggcc tgaacgtgaa cgccgtcggc accgtcaccg
     5101 gcctggtgga cggcatcgcc ccggtctccg gcctgctcaa caccgccgtc ggcaccgtcg
     5161 agggtgtcac cggcctgaac acggccccgg tcacgggcct ggtcgccggt ctctgatcgc
     5221 gcccttgcgt cgctgagtcc cggagccgtc caggctccgg gacttttcgg ccgttctccc
     5281 tccggccgtg atcgtccccc ggccgttctc accaagccct ggatacgtca gccgtgcagt
     5341 tccgccaaca ggccctcgca aaactccagt cgccggagga gctcgatctc ccggtgcgtt
     5401 tcgcccgtcc ccagggctgg ctggtgctgt ccgtgacgct gatcgccatg gccgccgcgt
     5461 ccgtgtgggc ggtgggcggc tcggtgacct ccacggtgtc cgcgcccgcc gtcctcaccc
     5521 acggccaggg cagttacctc ctgcagagcc ccgtctccgg gcaggtcacc gcggtcctcg
     5581 cccgtccggg gcagcggctg gccgccgacg ccccggtgct gaaggtccgc accgcgaagg
     5641 gcgagacggt ggtccgcacg gtggacgccg gccgggtcag cgcactcgcc gccaccgtcg
     5701 ggcagatcat cgccaccggc gcgaacgtcg cgtccgtcga gaaggtcgcc cacgccggcg
     5761 acccgctcta cgccaccgtc tacgtccccg cggagaacgc cgccgccatc cccgcccacg
     5821 cctcggtcga cctgaccgtc cagtcggtgc cgacgcagca gtacggcgtc ctgcacgggg
     5881 aggtgaagtc cgtggaccgc tcggcccagt cggcgcagac gatcggcgcg ttcctcgggg
     5941 acagcgcgct cggcgagcag ttcaccgagg acggcaggcc ggtggccgtg acggtgcggc
     6001 tggcaacctc gaagtccacg aagagcggct acgcgtggtc ctcggccgac gggccgccgt
     6061 tcgaactgac ctccatgacc ctggcctcgg gctcgatccg gctggccgac cagcgtcccg
     6121 tcgattggct gctgccgtga gcaccgcaca ggagacccgg ggcaggcgcc gtgccgcccc
     6181 gccgaggcgc agcgtgccga agagccgcgc gaggaccgtc cgcacgccca cggtgctcca
     6241 gatggaggcc gtggagtgcg gtgccgcctc cctcgccatg gtgctgggac actacggccg
     6301 ccatgtcccc ctggaggagc tgcggatcgc ctgcggtgtc tcccgcgacg ggtcccgggc
     6361 gagcaacctg ctgaaggccg cgcggagtta cgggttcacc gccaagggca tgcagatgga
     6421 cctggccgcc ctcgccgagg tgacggcacc ggccatcctc ttctgggagt tcaaccacta
     6481 cgtcgtctac gacggcatgg gccgccggtt cgggcggcgc ggggtgttca tcaacgaccc
     6541 gggcaaggga cgcaggttcg tgtccctgga ggacttcgac gggtccttca ccggtgtcgt
     6601 gctgaccatg gagcccggtg acggcttcac ccgcggcggc cgcaagcccg gtgtgctcgg
     6661 tgcgatgccc gcccggctgc gcggaaccgc gggcacgctg cccgccgcgg tgctggcgag
     6721 cctgctcctg gtggcggtcg gcgcggcggt gcccgcgctc agccgcacct acatcgacat
     6781 gttcctcatc ggtgggcaga cctcgctgct cggcgtgctg ttcgcgtcga tgggcgcctg
     6841 tgtgctgctc acggtggtgc tgacctggct ccagcaggcc aacctgctgc acgggcgcat
     6901 catctcctcc accctctcca gcgcccgctt cctgcggcac ctgctgcggc tgccggtgac
     6961 cttcttctcc cagcgcagcc ccgccgacct ggtgcagcgg ctccagtcca acgacgccgt
     7021 cgccgagacg ctggcccgcg acctcgccgc ggcgggcgtg gacgcgatcg tggtcgtcct
     7081 gtacgccgtg ctgctgtaca cgtacgaccc gcagctcacc ttcgtcggca tcggtgtggc
     7141 gctgctcaac atcctggcga tgcgggtcgt catccggctg cgcgcgaccc gtacggccaa
     7201 gctgcgggcg gacacggcgc ggctgaccaa caccgcctac accggcctcc agctgatcga
     7261 gacgatgaag gcgaccggcg gcgaggacgg ctacttccgc aagtgggccg gccagcacgc
     7321 caccacgctg gaggagcagc agcggctcgg ggtgcccagt gcctggctgg gcgtggtcgc
     7381 gccgacgctg gcgacgctga acagcgggct gatcctgtgg atcggcggca tgcgcgcggt
     7441 cgagggccac atctcggtcg ggctgctggt cgccttccag gcgctggtgg tccgcttcac
     7501 cgcgccgctg acccggctga acggtgtcgc gggccgcatc caggacttcg cggccgacgt
     7561 ggcccgcctc aaggacgtgg agaacttccg ggcggatccg ctctacgacc gccccggtga
     7621 cggcgactcc acccgccggc tgcgcgggca cgtggagctg cagaacgtct ccttcggcta
     7681 caacccgctc gacaagccgc tgctgtccgg tttcgacctg accgtggggc cggggcagca
     7741 ggtggccctg gtcggcggtt cgggcagcgg caagtcgacg gtgtcgcggc tgatctcggg
     7801 cctgtacgcg tcctgggacg gcgtgatccg catcgacggg cagcggctcg acgacatccc
     7861 gcgcggggcg ctggcgtcct ccgtctcctt cgtcgaccag gacgtgttcc tgttcgaggg
     7921 ctcggtgcgc gacaacgtgg ccctgtggga cccgtcgatc cccgacgacg ccgtggtgga
     7981 ggcgctgaag gacgccgcgc tgtacgacgt ggtgacgcgc aggccgggcg ggctccacag
     8041 cccggtggag caggacggcc gcaacttctc cggcgggcag cgccagcgcc tggagatcgc
     8101 gcgggccctg gtgcgccgcc ccagcatcct cgtcctggac gaggtgacca gcgcgctgga
     8161 cgcggagacc gagctggtgg tgatggacaa cctgcgccgg cgcggctgcg cctgcgtggt
     8221 gatcgcgcac cggctcagca cggtgcggga cagcgacgag atcgtcgtcc tcgaccacgg
     8281 cacggtcgtg gagcgcgggc ggcacgagga gctgctggcg cgcggtggcg cgtacgcggc
     8341 gctggtcagg gagcggtgag atgacaaccg tgcacgaggg gcagggcgac ctggtcctgg
     8401 gggcgctcgg ctcgctgggc acgcgcgtcg actgcgccgg gttcaaccgc ctcgacctgg
     8461 aggggccgca ggtgctgtgg ctcgtggtgt ccggcgcggt ggacctgttc gcggtcgacg
     8521 ccggggagca gggccactgg caccacctgg gacgcctgga ggcgggctcg gtactgctgg
     8581 gaccggtcgc cgggccgcag cacacgctgg tggcacgccc gctgcgggac tgcgtggtgc
     8641 accggatcgg gctgcgcgag ctgtaccagc cggcgcccac ccagacgtgg tcgtacgacg
     8701 cgtacggcaa cccccagtac gtgccgccga cgacgagtcc gctggagtac gccctggccc
     8761 tcggcgtggg acgcggcctg accgtcctct tccaggcgcc gatggccacg gagcgggccg
     8821 gcgcacccac ggacgacgac gtgttctgga tgcaggtgcc gccgggcagc gtgcagtacg
     8881 gggcggtgta cggcgaggag gcggccgccg acctgttgat ggacccggcg ctgtggcaga
     8941 gcatggtcga ccagcagtac cggctgctga ccacccttga ccggtggatc gagcagctgg
     9001 agcgcaccca cgagacccgc acggcggccg gtatcaaggc cggtgaggcg gtgcgcgcgc
     9061 gggccgaccg gacgctgctg gcctccatcg gcaagcgctc ggcgcagcgc accacggccg
     9121 ccgacgccga cgccacgtac gcggcgtgcg ggctggtcgc ccgcgccgcc ggtattccgc
     9181 tcgccgagcc gtccccgggc ggcaccgaga gcgaccggct ggacccggtg gagcggatcg
     9241 cgctcgcctc gcgggtgcgg accaggtcgg tgcggctggc ggaccgctgg tggcgggagg
     9301 acgtggggcc gctggtcggg caccgcaccc tgtcgggggc gccggtggct ctgctgtggc
     9361 ggcgcggcgg ctatgtggcc gtgcatccgg cgaccggtcg ggagacgccc gtggagcggg
     9421 cgaacgccgg ggagttcgaa ccgcgcgcgg tgatgttcta ccgcccgctg ccggagcggc
     9481 ggccgagtcc gctcgggctg ctccggttct gtctggcggg cacccgccgg gatctgacgt
     9541 cgctgctgct cgccgggctg gtgacggtgg tgctcggcgc gctggtgccg atcgcgacgg
     9601 gccgggtgct cggcgagttc gtgccgaagg cgcagaccgg gctgatcgtg caggtgtgtc
     9661 tcgcggtgat gctgagcagc gtcgtcgcgg cggccttcat gctgctgcag aacctcacca
     9721 tcctgcgtct ggagggccgg atcgaggcca ccctccagcc cgccgtgtgg gaccgcctgc
     9781 tgcggctgcc gacgaagttc ttcaccgagc gctccaccgg cgaactggcg agcgcggcca
     9841 tgggcatcag cgcgatccgc agactgctcg cgggggtcgg cccgaccgtg gcccagtcgg
     9901 tgaccgtcgg ggcgatgaac ctcggtctgc tgctctggta cagcgtgccg atggcgttcg
     9961 ccgcgatcgg catgctggtg gtcgtcgccg gggtgttcct cgggctcggg ctgtggcagg
    10021 tgcgctggca gcggcggctg gtcaaactca ccaacaagct gaacaaccag gcgttccaga
    10081 cgctgcgcgg gctgccgaag ctgcgggtgg cggcagccga gaactacgcc tacgcggcgt
    10141 gggcggagcg gttcgcgcac agccgggagc tgcagcagcg ggcgggccgg atcaagaacc
    10201 tgaacgcggt gctcgg
//
