LOCUS       NC_003888              28271 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    RefSeq; complete genome.
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces
            albidoflavus group.
REFERENCE   1  (bases 1 to 8667507)
  AUTHORS   Hsiao,N.H. and Kirby,R.
  TITLE     Comparative genomics of Streptomyces avermitilis, Streptomyces
            cattleya, Streptomyces maritimus and Kitasatospora aureofaciens
            using a Streptomyces coelicolor microarray system
  JOURNAL   Antonie Van Leeuwenhoek 93 (1-2), 1-25 (2008)
   PUBMED   17588127
REFERENCE   2  (bases 1 to 8667507)
  AUTHORS   Bentley,S.D., Chater,K.F., Cerdeno-Tarraga,A.M., Challis,G.L.,
            Thomson,N.R., James,K.D., Harris,D.E., Quail,M.A., Kieser,H.,
            Harper,D., Bateman,A., Brown,S., Chandra,G., Chen,C.W., Collins,M.,
            Cronin,A., Fraser,A., Goble,A., Hidalgo,J., Hornsby,T., Howarth,S.,
            Huang,C.H., Kieser,T., Larke,L., Murphy,L., Oliver,K., O'Neil,S.,
            Rabbinowitsch,E., Rajandream,M.A., Rutherford,K., Rutter,S.,
            Seeger,K., Saunders,D., Sharp,S., Squares,R., Squares,S., Taylor,K.,
            Warren,T., Wietzorrek,A., Woodward,J., Barrell,B.G., Parkhill,J. and
            Hopwood,D.A.
  TITLE     Complete genome sequence of the model actinomycete Streptomyces
            coelicolor A3(2)
  JOURNAL   Nature 417 (6885), 141-147 (2002)
   PUBMED   12000953
REFERENCE   3  (bases 1 to 8667507)
  AUTHORS   Redenbach,M., Kieser,H.M., Denapaite,D., Eichner,A., Cullum,J.,
            Kinashi,H. and Hopwood,D.A.
  TITLE     A set of ordered cosmids and a detailed genetic and physical map for
            the 8 Mb Streptomyces coelicolor A3(2) chromosome
  JOURNAL   Mol. Microbiol. 21 (1), 77-96 (1996)
   PUBMED   8843436
REFERENCE   4  (bases 1 to 8667507)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2002) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
  REMARK    Direct Submission
REFERENCE   5  (bases 1 to 8667507)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2002) Sanger Institute, Wellcome Trust Genome
            Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
  REMARK    Direct Submission
COMMENT     ##antiSMASH-Data-START##
            Version     :: 8.0.1
            Run date    :: 2025-05-26 12:13:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start :: 163767
            Orig. end   :: 192038
            ##antiSMASH-Data-END##
            REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..28271
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..28271
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28271
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:18271]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..18271
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(256..1227)
                     /db_xref="GeneID:1095598"
                     /gene_synonym="SCJ1.23c"
                     /locus_tag="SCO0174"
     CDS             complement(256..1227)
                     /codon_start=1
                     /db_xref="GeneID:1095598"
                     /gene_synonym="SCJ1.23c"
                     /locus_tag="SCO0174"
                     /note="SCJ1.23c, possible DNA-binding protein, len: 323 aa.
                     Similar in parts to many, e.g. Mycobacterium tuberculosis
                     TR:O53625 (EMBL; AL021428) hypothetical 16.6 KD protein
                     MTV030.24 (152 aa), fasta scores opt: 224 z-score: 258.5
                     E(): 4.9e-07 34.3% identity in 134 aa overlap and
                     Mycobacterium tuberculosis SW:YU07_MYCTU (EMBL; Z77163)
                     hypothetical 8.6 KD protein MTCY339.07C (80 aa), fasta
                     scores opt: 182 z-score: 216.4 E(): 0.00011 42.3% identity
                     in 71 aa overlap. Also similar to TR:Q9RJ05 (EMBL:AL109962)
                     Streptomyces coelicolor possible DNA-binding protein
                     SCJ1.09c, 233 aa; fasta scores: opt: 516 Z-score: 566.6
                     E(): 6.3e-24; 37.615% identity in 218 aa overlap. Contains
                     a Pfam match to entry PF01381 HTH_3, Helix-turn-helix and a
                     possible helix-turn-helix motif at residues 127..148 (+2.82
                     SD)"
                     /product="DNA-binding protein"
                     /protein_id="NP_624510.1"
                     /transl_table=11
                     /translation="MGAVSPREAGVRNSFDGEGAVMYAHLGDRLIVESPSTGVTRRDGE
                     IVGLHHDDGTPPYDVRWSDTGDVTLVFPGPDARVNHGAEEAEASQGAPSGVSRGEGVDS
                     SLIAAGAGDLGRRLAAARRRRGLSLEQVARRARMAPQYLAYLETHTADPGFGSLVRLAD
                     ALGTTYAELQGGGADRPPGQGAALRNPTLRDLDEKECRALLSAHGVGRLALNTPDGPAV
                     FPLNYVVSQGTIAFRTDPDAATAAAVDSEVAFEVDHIDDPMSQGWSVLAVGRCRAVTDP
                     EEVRRLAEKAHTEPWAGGRRTMWLAVETERLTGRRITSVSGS"
     PFAM_domain     complement(280..642)
                     /aSDomain="Pyridox_ox_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF12900.10"
                     /description="Pyridoxamine 5'-phosphate oxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0174_0049"
                     /evalue="4.80E-25"
                     /label="SCO0174"
                     /locus_tag="SCO0174"
                     /protein_end="316"
                     /protein_start="195"
                     /score="88.4"
                     /tool="antismash"
                     /translation="DEKECRALLSAHGVGRLALNTPDGPAVFPLNYVVSQGTIAFRTDP
                     DAATAAAVDSEVAFEVDHIDDPMSQGWSVLAVGRCRAVTDPEEVRRLAEKAHTEPWAGG
                     RRTMWLAVETERLTGRR"
     misc_feature    complement(712..876)
                     /gene_synonym="SCJ1.23c"
                     /locus_tag="SCO0174"
                     /note="Pfam match to entry PF01381 HTH_3, Helix-turn-helix,
                     score 39.60, E-value 7.1e-08"
     PFAM_domain     complement(712..891)
                     /aSDomain="HTH_31"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13560.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0174_0048"
                     /evalue="1.60E-11"
                     /label="SCO0174"
                     /locus_tag="SCO0174"
                     /protein_end="172"
                     /protein_start="112"
                     /score="44.5"
                     /tool="antismash"
                     /translation="DLGRRLAAARRRRGLSLEQVARRARMAPQYLAYLETHTADPGFGS
                     LVRLADALGTTYAEL"
     PFAM_domain     complement(991..1164)
                     /aSDomain="DUF1918"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08940.14"
                     /description="Domain of unknown function (DUF1918)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0174_0047"
                     /evalue="1.70E-24"
                     /label="SCO0174"
                     /locus_tag="SCO0174"
                     /protein_end="79"
                     /protein_start="21"
                     /score="85.4"
                     /tool="antismash"
                     /translation="MYAHLGDRLIVESPSTGVTRRDGEIVGLHHDDGTPPYDVRWSDTG
                     DVTLVFPGPDARV"
     gene            complement(1292..1639)
                     /db_xref="GeneID:1095599"
                     /gene_synonym="SCJ1.24c"
                     /locus_tag="SCO0175"
     CDS             complement(1292..1639)
                     /codon_start=1
                     /db_xref="GeneID:1095599"
                     /gene_synonym="SCJ1.24c"
                     /locus_tag="SCO0175"
                     /note="SCJ1.24c, unknown, len: 115 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_624511.1"
                     /transl_table=11
                     /translation="MTCSPAERSVGWSSRTGSAGSGPSDLADEIRLRHDADEAADAVHH
                     QDGGDVVMGQCLGDRLEGCVRSDVDDGPGHEITYSPVPHDEPPLGGEPPWSTDATAVRT
                     SSLSTCRSEPP"
     gene            1693..2088
                     /db_xref="GeneID:1095600"
                     /gene_synonym="SCJ1.25"
                     /locus_tag="SCO0176"
     CDS             1693..2088
                     /codon_start=1
                     /db_xref="GeneID:1095600"
                     /gene_synonym="SCJ1.25"
                     /locus_tag="SCO0176"
                     /note="SCJ1.25, unknown, len: 131 aa."
                     /product="hypothetical protein"
                     /protein_id="NP_624512.1"
                     /transl_table=11
                     /translation="MEAARLMVTEEVKCLTVVDEADRWVGVVSRGDLLRVSLRRDDALR
                     EETSRAVLIRTRGPAPTGMTVDVDEGRVTVGGRVDNGQPLPVIERLCLGVDGVASVDLH
                     VTGREDRTRPVDTLGRARPTTLHVDVP"
     PFAM_domain     1813..2007
                     /aSDomain="BON"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04972.20"
                     /description="BON domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0176_0050"
                     /evalue="4.80E-08"
                     /label="SCO0176"
                     /locus_tag="SCO0176"
                     /protein_end="105"
                     /protein_start="40"
                     /score="33.3"
                     /tool="antismash"
                     /translation="DDALREETSRAVLIRTRGPAPTGMTVDVDEGRVTVGGRVDNGQPL
                     PVIERLCLGVDGVASVDLHV"
     misc_feature    complement(2163..2177)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     gene            2266..2847
                     /db_xref="GeneID:1095601"
                     /gene_synonym="SCJ1.26"
                     /locus_tag="SCO0177"
     CDS             2266..2847
                     /codon_start=1
                     /db_xref="GeneID:1095601"
                     /gene_synonym="SCJ1.26"
                     /locus_tag="SCO0177"
                     /note="SCJ1.26, possible membrane protein, len: 193 aa.
                     Similar to Mycobacterium tuberculosis TR:P71991(EMBL;
                     Z81360) hypothetical 22.5 KD protein (210 aa), fasta scores
                     opt: 287 z-score: 333.1 E(): 3.4e-11 35.2% identity in 182
                     aa overlap and S. coelicolor TR:Q9ZBP2 (EMBL;AL034492) 50KD
                     proline rich protein (456 aa), fasta scores opt: 338
                     z-score: 385.2 E(): 4.3e-14 35.6% identity in 188 aa
                     overlap. Contains possible membrane-spanning hydrophobic
                     region."
                     /product="hypothetical protein"
                     /protein_id="NP_624513.1"
                     /transl_table=11
                     /translation="MRAGTTIRRSLWRWRRNPLRRREDVLEAWILLIVWLVVALAGPVA
                     GVLAAHASAHGAAQRRAERHSATATLVSDVSGSPLSTGTAGGRIEATVRWTAPDGTRHS
                     GKIPVDEAMKAGSRVTVWTDHRNQLTTAPPTTAQAGVDAAFMGAASSFAVVTAAAAGYY
                     GARVVLNRRRRAAWEHEWQDIGSQWGRAAS"
     gene            3124..3570
                     /db_xref="GeneID:1095602"
                     /gene_synonym="SCJ1.27"
                     /locus_tag="SCO0178"
     CDS             3124..3570
                     /codon_start=1
                     /db_xref="GeneID:1095602"
                     /gene_synonym="SCJ1.27"
                     /locus_tag="SCO0178"
                     /note="SCJ1.27, unknown, len: 148 aa. Weak similarity to
                     Mycobacterium tuberculosis SW:YW23_MYCTU (EMBL; Z74025)
                     hypothetical 33.9 KD protein MTCY39.23C (317 aa), fasta
                     scores opt: 201 z-score: 231.7 E(): 1.5e-05 33.1% identity
                     in 136 aa overlap and Mycobacterium tuberculosis TR:O06189
                     (EMBL; Z95387)hypothetical 31.7 KD protein MTCY1A10.09C
                     (297 aa), fasta scores opt: 199 z-score: 229.8 E(): 1.9e-05
                     33.3% identity in 153 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_624514.1"
                     /transl_table=11
                     /translation="MLVAQALSAAAVVVGHRGPHPFQGALIGSLATGLAAHSECPVVVV
                     GEPENPAGPVALGVDGSAAGAAAVRLPGDFRAGCGHHRRARLDGLERADAASPRRETEP
                     YACEPGMLAAEEGRLLAETLAGMCARYPEVRVERSTVHGVHGRR"
     PFAM_domain     3127..3258
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0178_0051"
                     /evalue="5.10E-08"
                     /label="SCO0178"
                     /locus_tag="SCO0178"
                     /protein_end="45"
                     /protein_start="1"
                     /score="33.7"
                     /tool="antismash"
                     /translation="LVAQALSAAAVVVGHRGPHPFQGALIGSLATGLAAHSECPVVVV"
     gene            complement(3677..4747)
                     /db_xref="GeneID:1095603"
                     /gene_synonym="SCJ1.28c"
                     /locus_tag="SCO0179"
     CDS             complement(3677..4747)
                     /NRPS_PKS="Domain: PKS_ER (23-337). E-value: 5e-10. Score:
                     30.9. Matches aSDomain: nrpspksdomains_SCO0179_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:1095603"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCJ1.28c"
                     /locus_tag="SCO0179"
                     /note="SCJ1.28c,possible zinc-containing dehydrogenase,
                     len: 356 aa. Similar to many including: Thermoanaerobacter
                     brockii SW:ADH_THEBR (EMBL; X64841) NADP-dependent alcohol
                     dehydrogenase (EC 1.1.1.2) (352 aa), fasta scores opt: 556
                     z-score: 601.1 E(): 4e-26 33.7% identity in 338 aa overlap
                     and Halobacterium volcanii TR:O34179 (EMBL; U95372)
                     dehydrogenase (389 aa), fasta scores opt: 715 z-score:
                     770.1 E(): 0 37.0% identity in 351 aa overlap. Contains a
                     Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases and a PS00059 Zinc-containing alcohol
                     dehydrogenases signature"
                     /product="zinc-containing dehydrogenase"
                     /protein_id="NP_624515.1"
                     /sec_met_domain="ADH_N (E-value: 2.1e-29, bitscore: 100.4,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.2e-25, bitscore:
                     87.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGYVFHGPGRSAWEDIPDPELKEPTDAIVRVDAVTICGTDLHIL
                     KGDVPEVRPGTVLGHEAVGEIVEVGTDVRTVRPGDRVLVSCITACGRCRYCREGVYGQC
                     LGGGGWILGHLINGTQAEYVRVPYADLSVHSLPGAVTDEDAVLLADIFPTAYEVGVLNG
                     RVSPGDTVVVVGAGPIGLAAVATARLFAPERIVVVDLATARLEAARKLGAEAVADARED
                     PEQLVADLTGGLGADVVIEAVGVPETFEMCTRVVRPGGHVANVGVHGRPATLHLEDLWS
                     KNVTVTTGLVDTRSTPTLLRMAASGRLPTGQLVTHTFPLERMEEAYEVFSAAADTGALK
                     VVLGGPKREVVAANAV"
     misc_feature    complement(3716..4720)
                     /gene_synonym="SCJ1.28c"
                     /locus_tag="SCO0179"
                     /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases, score 236.60, E-value 3.4e-67"
     aSDomain        complement(3737..4678)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO0179_PKS_ER.1"
                     /evalue="5.00E-10"
                     /label="SCO0179_PKS_ER.1"
                     /locus_tag="SCO0179"
                     /protein_end="337"
                     /protein_start="23"
                     /score="30.9"
                     /tool="antismash"
                     /translation="EPTDAIVRVDAVTICGTDLHILKGDVPEVRPGTVLGHEAVGEIVE
                     VGTDVRTVRPGDRVLVSCITACGRCRYCREGVYGQCLGGGGWILGHLINGTQAEYVRVP
                     YADLSVHSLPGAVTDEDAVLLADIFPTAYEVGVLNGRVSPGDTVVVVGAGPIGLAAVAT
                     ARLFAPERIVVVDLATARLEAARKLGAEAVADAREDPEQLVADLTGGLGADVVIEAVGV
                     PETFEMCTRVVRPGGHVANVGVHGRPATLHLEDLWSKNVTVTTGLVDTRSTPTLLRMAA
                     SGRLPTGQLVTHTFPLERMEEAYEVFSAAADTG"
     PFAM_domain     complement(3848..4216)
                     /aSDomain="ADH_zinc_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00107.29"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0179_0053"
                     /evalue="1.10E-24"
                     /label="SCO0179"
                     /locus_tag="SCO0179"
                     /protein_end="300"
                     /protein_start="177"
                     /score="87.1"
                     /tool="antismash"
                     /translation="PIGLAAVATARLFAPERIVVVDLATARLEAARKLGAEAVADARED
                     PEQLVADLTGGLGADVVIEAVGVPETFEMCTRVVRPGGHVANVGVHGRPATLHLEDLWS
                     KNVTVTTGLVDTRSTPTLL"
     PFAM_domain     complement(4358..4672)
                     /aSDomain="ADH_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08240.15"
                     /description="Alcohol dehydrogenase GroES-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0179_0052"
                     /evalue="5.20E-29"
                     /label="SCO0179"
                     /locus_tag="SCO0179"
                     /protein_end="130"
                     /protein_start="25"
                     /score="100.4"
                     /tool="antismash"
                     /translation="TDAIVRVDAVTICGTDLHILKGDVPEVRPGTVLGHEAVGEIVEVG
                     TDVRTVRPGDRVLVSCITACGRCRYCREGVYGQCLGGGGWILGHLINGTQAEYVRVPYA
                     D"
     misc_feature    complement(4529..4573)
                     /gene_synonym="SCJ1.28c"
                     /locus_tag="SCO0179"
                     /note="PS00059 Zinc-containing alcohol dehydrogenases
                     signature, GHE.{2}G.{5}[GA].{2}[IVSAC], info count = 21.8"
     regulatory      complement(4761..4766)
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(4883..4897)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.9"
                     /tool="antismash"
     gene            complement(4938..5789)
                     /db_xref="GeneID:1095604"
                     /gene_synonym="SCJ1.29c"
                     /locus_tag="SCO0180"
     CDS             complement(4938..5789)
                     /codon_start=1
                     /db_xref="GeneID:1095604"
                     /gene_synonym="SCJ1.29c"
                     /locus_tag="SCO0180"
                     /note="SCJ1.29c, unknown, len: 283 aa. Similar to many
                     including: Mycobacterium tuberculosis TR:O53472 (EMBL;
                     AL021899) hypothetical 31.5 KD protein (294 aa), fasta
                     scores opt: 329 z-score: 389.0 E(): 2.6e-14 32.1% identity
                     in 293 aa overlap and Mycobacterium tuberculosis TR:O06189
                     (EMBL; Z95387) hypothetical 31.7 KD protein (297 aa), fasta
                     scores opt: 330 z-score: 390.1 E(): 2.3e-14 31.8% identity
                     in 296 aa overlap. Also similar to S. coelicolor SCJ1.16c
                     (294 aa), fasta scores opt: 806 z-score: 748.1 E():0 46.1%
                     identity in 295 aa overlap. Contains a Pfam match to entry
                     PF00582 Usp, Universal stress protein family"
                     /product="hypothetical protein"
                     /protein_id="NP_624516.1"
                     /transl_table=11
                     /translation="MYLPLVVGVDGSEPSLRAVDWAADEAALHAVPLWVVFGDLWERYE
                     GAALAREPGKPSTDMQADDILAAAAIRAGRRHPDLVVTTETVPDEAEHALICAGRNASM
                     IVMGSRGRSGIADRLLGSVSRTVAAGSDCPVVVLRGNHDNRAIGGRNGRIVVGVGEVSA
                     SVLRLAFMEARLRQVPVAAVRAWRCPAHETIDHPLPAGEPARRYEERAARELEAALEDA
                     PPDVAVRRYTVEGPARAVLPAASAEAGLLVIGRRTQGRLGRVAHAVLHRSACPVVVVPE
                     RT"
     PFAM_domain     complement(4950..5336)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0180_0055"
                     /evalue="2.40E-13"
                     /label="SCO0180"
                     /locus_tag="SCO0180"
                     /protein_end="280"
                     /protein_start="151"
                     /score="50.9"
                     /tool="antismash"
                     /translation="GRIVVGVGEVSASVLRLAFMEARLRQVPVAAVRAWRCPAHETIDH
                     PLPAGEPARRYEERAARELEAALEDAPPDVAVRRYTVEGPARAVLPAASAEAGLLVIGR
                     RTQGRLGRVAHAVLHRSACPVVVVP"
     PFAM_domain     complement(5373..5789)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0180_0054"
                     /evalue="1.30E-25"
                     /label="SCO0180"
                     /locus_tag="SCO0180"
                     /protein_end="139"
                     /protein_start="0"
                     /score="90.7"
                     /tool="antismash"
                     /translation="MYLPLVVGVDGSEPSLRAVDWAADEAALHAVPLWVVFGDLWERYE
                     GAALAREPGKPSTDMQADDILAAAAIRAGRRHPDLVVTTETVPDEAEHALICAGRNASM
                     IVMGSRGRSGIADRLLGSVSRTVAAGSDCPVVVLR"
     misc_feature    complement(5376..5714)
                     /gene_synonym="SCJ1.29c"
                     /locus_tag="SCO0180"
                     /note="Pfam match to entry PF00582 Usp, Universal stress
                     protein family, score 34.80, E-value 2e-06"
     regulatory      complement(5796..5803)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(5817..6803)
                     /db_xref="GeneID:1095605"
                     /gene_synonym="SCJ1.30c"
                     /locus_tag="SCO0181"
     CDS             complement(5817..6803)
                     /codon_start=1
                     /db_xref="GeneID:1095605"
                     /gene_synonym="SCJ1.30c"
                     /locus_tag="SCO0181"
                     /note="SCJ1.30c, unknown, len: 328 aa. Similar to many
                     including: Mycobacterium tuberculosis SW:YW23_MYCTU (EMBL;
                     Z74025) hypothetical 33.9 KD protein MTCY39.23C (317 aa)
                     fasta scores opt: 382 z-score: 439.2 E(): 4.2e-17 32.6%
                     identity in 319 aa overlap and Mycobacterium tuberculosis
                     TR:O53472 (EMBL; AL021899) hypothetical 31.5 KD protein
                     (294 aa), fasta scores opt: 382 z-score: 439.2 E(): 4.2e-17
                     32.6% identity in 319 aa overlap. Contains a Pfam match to
                     entry PF00582 Usp, Universal stress protein family."
                     /product="hypothetical protein"
                     /protein_id="NP_624517.1"
                     /transl_table=11
                     /translation="MSEDEWPYPGAQLRDTLESEGPTREVRDMTRTITVGIDGSPESHA
                     AAEWAAREAELRDLPVRLLHVWEPAPAVLAQDSILGAKTHQHWTERVPQKVGEGLRLRH
                     PGVVVTSDQRSGPPADTLVRDADGAELLVLGSRAPSGLGGFLAGSVGQSVIAHSETPVV
                     LVRAGEQAAGEHVVDSVGVPPAANRRRPVVVGLDIGSPDDGVLSFAFDEAQRRGTAVHV
                     VSGWRPPPYYPSLTAGGVPDQGVARRKAADLTRLLLPWRQSYPDVEVVEASRPGSPADL
                     LAEASHEASLVVVGRRIRPSPLGVHIGAVAHAVLHRVSAPVAVVAHP"
     misc_feature    complement(5829..6152)
                     /gene_synonym="SCJ1.30c"
                     /locus_tag="SCO0181"
                     /note="Pfam match to entry PF00582 Usp, Universal stress
                     protein family, score 42.80, E-value 7.5e-09"
     PFAM_domain     complement(5829..6236)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0181_0057"
                     /evalue="1.80E-17"
                     /label="SCO0181"
                     /locus_tag="SCO0181"
                     /protein_end="325"
                     /protein_start="189"
                     /score="64.3"
                     /tool="antismash"
                     /translation="RPVVVGLDIGSPDDGVLSFAFDEAQRRGTAVHVVSGWRPPPYYPS
                     LTAGGVPDQGVARRKAADLTRLLLPWRQSYPDVEVVEASRPGSPADLLAEASHEASLVV
                     VGRRIRPSPLGVHIGAVAHAVLHRVSAPVAVV"
     PFAM_domain     complement(6306..6719)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0181_0056"
                     /evalue="3.20E-26"
                     /label="SCO0181"
                     /locus_tag="SCO0181"
                     /protein_end="166"
                     /protein_start="28"
                     /score="92.7"
                     /tool="antismash"
                     /translation="MTRTITVGIDGSPESHAAAEWAAREAELRDLPVRLLHVWEPAPAV
                     LAQDSILGAKTHQHWTERVPQKVGEGLRLRHPGVVVTSDQRSGPPADTLVRDADGAELL
                     VLGSRAPSGLGGFLAGSVGQSVIAHSETPVVLVR"
     gene            complement(6889..7113)
                     /db_xref="GeneID:1095606"
                     /gene_synonym="SCJ1.31c"
                     /locus_tag="SCO0182"
     CDS             complement(6889..7113)
                     /codon_start=1
                     /db_xref="GeneID:1095606"
                     /gene_synonym="SCJ1.31c"
                     /locus_tag="SCO0182"
                     /note="SCJ1.31c, doubtful CDS, len: 74 aa. Contains a
                     TTA/leucine codon, possible target for bldA regulation."
                     /product="hypothetical protein"
                     /protein_id="NP_624518.1"
                     /transl_table=11
                     /translation="MCRAAVGVLEAGARREGVTCGTYGLWDGVTAWREPRSSMPDLTQV
                     LKPIEGSDLVPAASVVAAHAEDRLKGEGH"
     misc_feature    complement(7039..7041)
                     /gene_synonym="SCJ1.31c"
                     /locus_tag="SCO0182"
                     /note="TTA/leucine codon, possible target for bldA
                     regulation."
     misc_feature    complement(7039..7041)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7144..8391
                     /db_xref="GeneID:1095607"
                     /gene_synonym="SCJ1.32"
                     /locus_tag="SCO0183"
     CDS             7144..8391
                     /codon_start=1
                     /db_xref="GeneID:1095607"
                     /gene_synonym="SCJ1.32"
                     /locus_tag="SCO0183"
                     /note="SCJ1.32, unknown,len: 415 aa. Likely to have arisen
                     as a result of a duplication of SCF43A.31/32, followed by a
                     deletion event generating a possible CDS with the 5' coding
                     sequence of SCF43A.31 and the 3' coding sequence of
                     SCF43A.32. Similarity scores are as follows: to
                     Streptomyces coelicolor TR:CAB48918 (EMBL; AL096837)
                     oxidoreductase SCF43A.31 (520 aa), fasta scores opt: 1191
                     z-score: 1365.3 E(): 0 64.2% identity in 307 aa overlap and
                     to Streptomyces coelicolor TR:CAB48919(EMBL; AL096837)
                     deoxyribodipyrimidine photolyase SCF43A.32 (458 aa), opt:
                     909 z-score: 1043.2 E(): 0 45.7% identity in 418 aa
                     overlap. Contains a PS00394 DNA photolyases class 1
                     signature 1 and a PS00691 DNA photolyases class 1 signature
                     2."
                     /product="deoxiribopirymidine photolyase"
                     /protein_id="NP_624519.1"
                     /transl_table=11
                     /translation="MRRIVYLGGLTPRGVPERTLSPHLRSRAEVGPILVRDVLHYLAGA
                     ATMPDDIDRAFDVGGPDVPTYREMMRRHATVSGLRRRIIVPAPVLTPGLSSHWVGLVTP
                     VPASIARPLTESLRHEVVCQEHDIARYVPDAPGRPLPFDVALTLALRRVREAQVATRWS
                     SASVPGAPSDPLPTDPDWAGGSLYEDERHLPVDASPEALWKVVEGIGGDNGWYSFPPAW
                     AVRGWLDRFVGGVGLRRGRRDAQRLHPARPVAWRGGRRRGHRRLAGRTGYPVVDAAMRQ
                     LRHQGWMHNRARLLVASFLTKTLYVDWRIGARHFLDLLVDGDVVNNQLNWQWAAGTGTD
                     TRPHRVLNPLVQARRFDPDGVYVRRWVPELRSVEGGKVHEPWRLAAAERGELDYPDPLV
                     ELADGLARFKHARGRD"
     PFAM_domain     7684..7899
                     /aSDomain="DUF2867"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF11066.11"
                     /description="Protein of unknown function (DUF2867)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0183_0058"
                     /evalue="3.90E-13"
                     /label="SCO0183"
                     /locus_tag="SCO0183"
                     /protein_end="252"
                     /protein_start="180"
                     /score="50.1"
                     /tool="antismash"
                     /translation="WAGGSLYEDERHLPVDASPEALWKVVEGIGGDNGWYSFPPAWAVR
                     GWLDRFVGGVGLRRGRRDAQRLHPARP"
     PFAM_domain     7942..8364
                     /aSDomain="FAD_binding_7"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03441.17"
                     /description="FAD binding domain of DNA photolyase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0183_0059"
                     /evalue="2.70E-58"
                     /label="SCO0183"
                     /locus_tag="SCO0183"
                     /protein_end="407"
                     /protein_start="266"
                     /score="197.0"
                     /tool="antismash"
                     /translation="AGRTGYPVVDAAMRQLRHQGWMHNRARLLVASFLTKTLYVDWRIG
                     ARHFLDLLVDGDVVNNQLNWQWAAGTGTDTRPHRVLNPLVQARRFDPDGVYVRRWVPEL
                     RSVEGGKVHEPWRLAAAERGELDYPDPLVELADGLAR"
     misc_feature    7951..7989
                     /gene_synonym="SCJ1.32"
                     /locus_tag="SCO0183"
                     /note="PS00394 DNA photolyases class 1 signature 1"
     misc_feature    8011..8070
                     /gene_synonym="SCJ1.32"
                     /locus_tag="SCO0183"
                     /note="PS00691 DNA photolyases class 1 signature 2"
     gene            8403..10217
                     /db_xref="GeneID:1095608"
                     /gene_synonym="SCJ1.33"
                     /locus_tag="SCO0184"
     CDS             8403..10217
                     /codon_start=1
                     /db_xref="GeneID:1095608"
                     /gene_synonym="SCJ1.33"
                     /locus_tag="SCO0184"
                     /note="SCJ1.33 unknown, len: 604 aa. Highly similar to
                     Synechocystis sp. (strain PCC6803) TR:P74080 (EMBL;D90912)
                     hypothetical 58.1 KD protein (504 aa), fasta scores opt:
                     931 z-score: 996.4 E(): 0 38.8% identity in 479 aa overlap
                     and Methanobacterium thermoautotrophicum TR:O27804
                     (EMBL;AE000932) conserved protein MTH1776 (491 aa), fasta
                     scores opt: 572 z-score: 613.5 E(): 8.1e-27 31.7% identity
                     in 483 aa overlap. Also shares a low level of similarity
                     with Streptomyces coelicolor TR:CAB48919 (EMBL;AL096837)
                     deoxyribodipyrimidine photolyase SCF43A.32 (458 aa), fasta
                     scores opt: 176 z-score: 191.4 E(): 0.0026 31.1% identity
                     in 219 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_624520.1"
                     /transl_table=11
                     /translation="MHWLFGDQLGPHFLTPGEEGPGPETPLLMIEARSVFRRRRFHRAK
                     AHLVLSAMRHRAAEPGDRVTYVRADTYRQGLARTARGRPVGVHHPTSHAALRLVRALPQ
                     VTVGPARGFLVPMTGFAAWAEGHGGKRLRQEDFYRWVRRGHGLLMDGEQPAAGRWNLDH
                     DNREPPPREAASLQVGRPYRPREDDIDEEVRHDLDRWERDGDVSFVGRDGPRLFPATRT
                     EGLRALRRFVEHRLATFGPHEDAMLAADPVMSHSLLSSTLNLGPLDPVECVERAERAWR
                     EGRAPLNSVEGFVRQIAGWREYVWQLYWYFGEGYRRSNALGHTAPLPDWWNRLDADAVR
                     ANCLRTVLAQVRDTGWTHHIPRLMVLGSHALQRGWDPAAVTNWFHRCFVDGYDWVMLPN
                     VVGMSQYADGGRMTTKPYTSAGAYVNRMSDLCGPCGYRPGDRTCEHACPYTTGYWAFLD
                     RHRELLAGNQRVARPVRQSDRLADLPDVCAQGTRGVTHRHEPPPLRRRGEVGPHPVPER
                     AEVSASTTGHPAEAVACGQPRVRRGCACLDCRRWWPRRPNRSTTPSPRPMRRTRSTPSS
                     GGYWTNGCATAVPSTPSSPGNWPTVSRR"
     PFAM_domain     8409..8999
                     /aSDomain="DPRP"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04244.16"
                     /description="Deoxyribodipyrimidine photo-lyase-related
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0184_0060"
                     /evalue="3.50E-31"
                     /label="SCO0184"
                     /locus_tag="SCO0184"
                     /protein_end="199"
                     /protein_start="2"
                     /score="108.9"
                     /tool="antismash"
                     /translation="WLFGDQLGPHFLTPGEEGPGPETPLLMIEARSVFRRRRFHRAKAH
                     LVLSAMRHRAAEPGDRVTYVRADTYRQGLARTARGRPVGVHHPTSHAALRLVRALPQVT
                     VGPARGFLVPMTGFAAWAEGHGGKRLRQEDFYRWVRRGHGLLMDGEQPAAGRWNLDHDN
                     REPPPREAASLQVGRPYRPREDDIDEEVRHDLDR"
     gene            10001..11179
                     /db_xref="GeneID:1095609"
                     /gene_synonym="crtB; SCJ1.34"
                     /locus_tag="SCO0185"
     CDS             10001..11179
                     /codon_start=1
                     /db_xref="GeneID:1095609"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /gene_synonym="crtB; SCJ1.34"
                     /locus_tag="SCO0185"
                     /note="SCJ1.34, crtB, possible geranylgeranyl pyrophosphate
                     synthase, len: 392 aa. Shares a high level of similarity
                     with Streptomyces griseus TR:Q54193 (EMBL:L37405)
                     geranylgeranyl pyrophosphate synthase (425 aa), fasta
                     scores: opt: 964 z-score: 1076.9 E(): 0 48.0% identity in
                     381 aa overlap and Mycobacterium tuberculosis TR:O53507
                     (EMBL:AL021957) geranylgeranyl pyrophosphate synthase (352
                     aa), fasta scores opt: 742 z-score: 831.2 E(): 0 43.0%
                     identity in 328 aa overlap. Contains a PS00723 Polyprenyl
                     synthetases signature 1"
                     /product="geranylgeranyl pyrophosphate synthase"
                     /protein_id="NP_624521.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.4e-45, bitscore:
                     152.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTTESEKGLRMPGLPPMVAPPAEQVDDPVTATDAANAVDAVLRG
                     VLDERLRHCRAVDPLFARELADRLAALTARGGKRLRTAFAHCGWRAAGGSGDATAVLRT
                     GAALELLQACALVHDDVMDGSVQRRGAPALHVDLARGHWAAGMHGSSESFGTSAAVLTG
                     DLALAWADDLLTETALGTPHGPRLHGEWRAMRTEMVAGQYRDLHAQAARSSGVDEALAI
                     ATLKSALYTVARPLALGAVLAGAADGDALEALRAAGRCAGLAFQLRDDLLGAFGDPALT
                     GKPADDDLRSRKLTYLLAVAVRLADAADDHLAAAALAPDADPKSEKAVRQVRSALVRTG
                     ARDLVETKIGELTDMSLAHFDRCGARPAVRHEFAALIGRATGAVPRGTGEVV"
     PFAM_domain     10193..10999
                     /aSDomain="polyprenyl_synt"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00348.20"
                     /db_xref="GO:0008299"
                     /description="Polyprenyl synthetase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0185_0061"
                     /evalue="1.20E-45"
                     /gene_ontologies="GO:0008299: isoprenoid biosynthetic
                     process"
                     /label="SCO0185"
                     /locus_tag="SCO0185"
                     /protein_end="333"
                     /protein_start="64"
                     /score="155.7"
                     /tool="antismash"
                     /translation="LADRLAALTARGGKRLRTAFAHCGWRAAGGSGDATAVLRTGAALE
                     LLQACALVHDDVMDGSVQRRGAPALHVDLARGHWAAGMHGSSESFGTSAAVLTGDLALA
                     WADDLLTETALGTPHGPRLHGEWRAMRTEMVAGQYRDLHAQAARSSGVDEALAIATLKS
                     ALYTVARPLALGAVLAGAADGDALEALRAAGRCAGLAFQLRDDLLGAFGDPALTGKPAD
                     DDLRSRKLTYLLAVAVRLADAADDHLAAAALAPDADPKSEKAVRQVR"
     misc_feature    10346..10390
                     /gene_synonym="crtB; SCJ1.34"
                     /locus_tag="SCO0185"
                     /note="PS00723 Polyprenyl synthetases signature 1,
                     [LIVM]{2}.DD.{2,4}D.{4}RR[GH], info count = 26.9"
     gene            11176..12747
                     /db_xref="GeneID:1095610"
                     /gene_synonym="crtE; SCJ1.35"
                     /locus_tag="SCO0186"
     CDS             11176..12747
                     /codon_start=1
                     /db_xref="GeneID:1095610"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="crtE; SCJ1.35"
                     /locus_tag="SCO0186"
                     /note="SCJ1.35, crtE, probable phytoene dehydrogenase
                     (phytoene desaturase) (hypothetical protein), len: 523 aa.
                     High level of similarity to Streptomyces griseus
                     SW:CRTI_STRGR (EMBL; L37405) phytoene dehydrogenase (EC
                     1.3.-.-) (phytoene desaturase) (507 aa), fasta scores opt:
                     2459 z-score: 2615.3 E(): 0; 74.5% identity in 501 aa
                     overlap and Streptomyces setonii SW:CRTI_STRSE (EMBL;
                     D55723) phytoene dehydrogenase (EC 1.3.-.-) (phytoene
                     desaturase) (508 aa), fasta scores opt: 2455 z-score:
                     2611.0 E(): 0; 74.3% identity in 498 aa overlap. Contains a
                     PS00982 Bacterial-type phytoene dehydrogenase signature"
                     /product="phytoene dehydrogenase"
                     /protein_id="NP_624522.1"
                     /sec_met_domain="DAO (E-value: 9.7e-17, bitscore: 60.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVPGPTGHVVVVGAGLSGLACALHLLGAGRRVTVVERDAGPGG
                     RSGRVRLGGYELDTGPTVLTMPHLADEAFAAVGDSLRRRVELTALDPAYRACFADGSAL
                     DVHTDGEAMEAEVRRFAGPAQAAGYRDLRRWLERLYRAQMRRFIDTNFDSPLQLLHPDL
                     ARLAALGGFGRLDGRIGRFLSDERLRRVFSFQALYAGVAPARALAAYAVIAYMDTVAGV
                     WFPKGGMHALPRAMADAAATAGADLRWSAEVKALERSAGRVRAVHLASGERIACDAVVL
                     TCELSTAYGLLGRAPRRPARLRHSPSAVILHAGTDRTWPHLAHHTLSFGAAWERTFEEL
                     TRTGELMSDPSLLITRPTTHDPALAPPGRHLHYVLAPCPNTDVGPDAVAWRDLGPRYRE
                     SLVGVLESRGLEGFADSVQEELLVTPLDWDAQGHAAGSPFSVSHTFAQTGPFRPRNLVR
                     GLDNVVLAGCGTTPGVGVPTVLVSGKLAAARVTGGAGSRPARTRRSPAVSDPCPAPVPA
                     GADDPS"
     aSDomain        11206..12687
                     /aSDomain="TIGR02734"
                     /aSTool="tigrfam"
                     /description="crtI_fam: phytoene desaturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO0186_0003"
                     /evalue="2.30E-179"
                     /identifier="TIGR02734"
                     /label="SCO0186"
                     /locus_tag="SCO0186"
                     /protein_end="504"
                     /protein_start="10"
                     /score="595.3"
                     /tool="antismash"
                     /translation="VVVVGAGLSGLACALHLLGAGRRVTVVERDAGPGGRSGRVRLGGY
                     ELDTGPTVLTMPHLADEAFAAVGDSLRRRVELTALDPAYRACFADGSALDVHTDGEAME
                     AEVRRFAGPAQAAGYRDLRRWLERLYRAQMRRFIDTNFDSPLQLLHPDLARLAALGGFG
                     RLDGRIGRFLSDERLRRVFSFQALYAGVAPARALAAYAVIAYMDTVAGVWFPKGGMHAL
                     PRAMADAAATAGADLRWSAEVKALERSAGRVRAVHLASGERIACDAVVLTCELSTAYGL
                     LGRAPRRPARLRHSPSAVILHAGTDRTWPHLAHHTLSFGAAWERTFEELTRTGELMSDP
                     SLLITRPTTHDPALAPPGRHLHYVLAPCPNTDVGPDAVAWRDLGPRYRESLVGVLESRG
                     LEGFADSVQEELLVTPLDWDAQGHAAGSPFSVSHTFAQTGPFRPRNLVRGLDNVVLAGC
                     GTTPGVGVPTVLVSGKLAAARVTGGAGSRPARTRRS"
     PFAM_domain     11227..12645
                     /aSDomain="Amino_oxidase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01593.27"
                     /db_xref="GO:0016491"
                     /description="Flavin containing amine oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0186_0062"
                     /evalue="2.50E-58"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO0186"
                     /locus_tag="SCO0186"
                     /protein_end="490"
                     /protein_start="17"
                     /score="198.6"
                     /tool="antismash"
                     /translation="LSGLACALHLLGAGRRVTVVERDAGPGGRSGRVRLGGYELDTGPT
                     VLTMPHLADEAFAAVGDSLRRRVELTALDPAYRACFADGSALDVHTDGEAMEAEVRRFA
                     GPAQAAGYRDLRRWLERLYRAQMRRFIDTNFDSPLQLLHPDLARLAALGGFGRLDGRIG
                     RFLSDERLRRVFSFQALYAGVAPARALAAYAVIAYMDTVAGVWFPKGGMHALPRAMADA
                     AATAGADLRWSAEVKALERSAGRVRAVHLASGERIACDAVVLTCELSTAYGLLGRAPRR
                     PARLRHSPSAVILHAGTDRTWPHLAHHTLSFGAAWERTFEELTRTGELMSDPSLLITRP
                     TTHDPALAPPGRHLHYVLAPCPNTDVGPDAVAWRDLGPRYRESLVGVLESRGLEGFADS
                     VQEELLVTPLDWDAQGHAAGSPFSVSHTFAQTGPFRPRNLVRGLDNVVLAGCGTTPGVG
                     VPTVLVSGKLAAARV"
     misc_feature    12559..12621
                     /gene_synonym="crtE; SCJ1.35"
                     /locus_tag="SCO0186"
                     /note="PS00982 Bacterial-type phytoene dehydrogenase
                     signature"
     gene            12734..13729
                     /db_xref="GeneID:1095611"
                     /gene_synonym="crtI; SCJ1.36"
                     /locus_tag="SCO0187"
     CDS             12734..13729
                     /codon_start=1
                     /db_xref="GeneID:1095611"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /gene_synonym="crtI; SCJ1.36"
                     /locus_tag="SCO0187"
                     /note="SCJ1.36, crtI, probable phytoene synthase, len: 331
                     aa. Shares a high level of similarity with Streptomyces
                     griseus SW:CRTB_STRGR (EMBL; L37405) phytoene synthase (342
                     aa), fasta scores opt: 1388 z-score: 1657.5 E(): 0 67.6%
                     identity in 343 aa overlap and Mycobacterium marinum TR:
                     O05423 (EMBL; U92075) phytoene synthase (319 aa), fasta
                     scores opt: 996 z-score: 1191.5 E():0 52.2% identity in 316
                     aa overlap. Contains a PS01045 Squalene and phytoene
                     synthases signature 2 and a Pfam match to entry PF00494
                     SQS_PSY, Squalene and phytoene synthases"
                     /product="phytoene synthase"
                     /protein_id="NP_624523.1"
                     /sec_met_domain="phytoene_synt (E-value: 7.3e-127,
                     bitscore: 421.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.8e-63,
                     bitscore: 213.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRELDAAGITDPLLRAAYTRCRRLNARHGKTYFLATRLLPLER
                     RSAVHALYGFARWADDIVDDLDRHRTAGERDRALRRLESDLADGLRTGTGREPVVRAVA
                     DTADRYDIDHVLFADFLSSMRADLTVTHYPTYADLQAYVHGSAAVIGLQMLPVLGTVTD
                     RKEAAPHAAALGVAFQLTNFLRDVGEDLDRGRVYLPGSLLAAHGVDRPLLEWSRRTGRR
                     DRRIRAALVAAEAMTRRVYRTAEPGIAMLDPRVRPCIRAAFTLYGGILDAIAEQDYTVL
                     HRRAVVSRRRRAATAAEGVLCVAAARWRARTSPRVEAAGGPAAEWQGPVR"
     PFAM_domain     12818..13606
                     /aSDomain="SQS_PSY"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00494.22"
                     /db_xref="GO:0009058"
                     /description="Squalene/phytoene synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0187_0063"
                     /evalue="5.70E-61"
                     /gene_ontologies="GO:0009058: biosynthetic process"
                     /label="SCO0187"
                     /locus_tag="SCO0187"
                     /protein_end="291"
                     /protein_start="28"
                     /score="206.4"
                     /tool="antismash"
                     /translation="RHGKTYFLATRLLPLERRSAVHALYGFARWADDIVDDLDRHRTAG
                     ERDRALRRLESDLADGLRTGTGREPVVRAVADTADRYDIDHVLFADFLSSMRADLTVTH
                     YPTYADLQAYVHGSAAVIGLQMLPVLGTVTDRKEAAPHAAALGVAFQLTNFLRDVGEDL
                     DRGRVYLPGSLLAAHGVDRPLLEWSRRTGRRDRRIRAALVAAEAMTRRVYRTAEPGIAM
                     LDPRVRPCIRAAFTLYGGILDAIAEQDYTVLHRRAVVSRRR"
     misc_feature    12878..13648
                     /gene_synonym="crtI; SCJ1.36"
                     /locus_tag="SCO0187"
                     /note="Pfam match to entry PF00494 SQS_PSY, Squalene and
                     phytoene synthases, score 253.20, E-value 3.5e-72"
     misc_feature    13253..13330
                     /gene_synonym="crtI; SCJ1.36"
                     /locus_tag="SCO0187"
                     /note="PS01045 Squalene and phytoene synthases signature 2"
     gene            13726..14736
                     /db_xref="GeneID:1095612"
                     /gene_synonym="crtV; SCJ1.37"
                     /locus_tag="SCO0188"
     CDS             13726..14736
                     /codon_start=1
                     /db_xref="GeneID:1095612"
                     /gene_synonym="crtV; SCJ1.37"
                     /locus_tag="SCO0188"
                     /note="SCJ1.37, crtV, probable methylesterase, len: 336 aa.
                     Highly similar to Streptomyces griseus TR:P72448 (EMBL;
                     X95596) methylesterase (338 aa), fasta scores opt: 1315
                     z-score: 1538.7 E(): 0 60.5% identity in 337 aa overlap"
                     /product="methylesterase"
                     /protein_id="NP_624524.1"
                     /transl_table=11
                     /translation="MSGRRGGRRWSPPVRRRGAGPDWAAQTPTWRQARPSLIADALERA
                     SARPSGNWFVVGASRQVRAGDRPYGRTVGGVEVVLWRSDDGEPRAGSGICPHLGAPLRD
                     SRVVCGTLVCHWHGLALDGSASAGWRPFPVHDDGVLVWVRLDEVGGEEPTERPVVPTRP
                     ATGRGVDSVFTATGRCEPQDVVANRLDPWHGSWFHPYSFVDLSVVREPQGGEDDAFVVD
                     VSFRVAGRLVVPVRAEFTAPEPRTVVMRITDGEGATSVVETHATPLTGPDHERPRTAVV
                     EAVVAASDRPGFALARAAAPVLRPLMRRTAGRLWRDDLAYAERRWALRSTGRFPG"
     PFAM_domain     13879..14115
                     /aSDomain="Rieske"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00355.29"
                     /db_xref="GO:0051537"
                     /description="Rieske [2Fe-2S] domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0188_0064"
                     /evalue="1.90E-13"
                     /gene_ontologies="GO:0051537: 2 iron, 2 sulfur cluster
                     binding"
                     /label="SCO0188"
                     /locus_tag="SCO0188"
                     /protein_end="130"
                     /protein_start="51"
                     /score="50.3"
                     /tool="antismash"
                     /translation="NWFVVGASRQVRAGDRPYGRTVGGVEVVLWRSDDGEPRAGSGICP
                     HLGAPLRDSRVVCGTLVCHWHGLALDGSASAGWR"
     PFAM_domain     14167..14724
                     /aSDomain="DUF5914"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19299.2"
                     /description="Domain of unknown function (DUF5914)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0188_0065"
                     /evalue="6.80E-96"
                     /label="SCO0188"
                     /locus_tag="SCO0188"
                     /protein_end="333"
                     /protein_start="147"
                     /score="319.4"
                     /tool="antismash"
                     /translation="VGGEEPTERPVVPTRPATGRGVDSVFTATGRCEPQDVVANRLDPW
                     HGSWFHPYSFVDLSVVREPQGGEDDAFVVDVSFRVAGRLVVPVRAEFTAPEPRTVVMRI
                     TDGEGATSVVETHATPLTGPDHERPRTAVVEAVVAASDRPGFALARAAAPVLRPLMRRT
                     AGRLWRDDLAYAERRWALRSTGR"
     gene            complement(14752..16320)
                     /db_xref="GeneID:1095613"
                     /gene_synonym="crtU; SCJ1.38c"
                     /locus_tag="SCO0189"
     CDS             complement(14752..16320)
                     /codon_start=1
                     /db_xref="GeneID:1095613"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="crtU; SCJ1.38c"
                     /locus_tag="SCO0189"
                     /note="SCJ1.38c, crtU, probable dehydrogenase, a partial
                     CDS, len: >336 aa. Highly similar to Streptomyces griseus
                     TR:P72449 (EMBL:X95596) dehydrogenase (517 aa), fasta
                     scores opt: 1277 z-score: 1459.8 E():0 69.0% identity in
                     281 aa overlap and Synechocystis sp SW:CRTI_SYNY3 (EMBL;
                     X62574) phytoene dehydrogenase (427 aa), fasta scores opt:
                     133 z-score: 155.8 E():0.25 24.6% identity in 260 aa
                     overlap.; SCJ12.01c, crtU, probable dehydrogenase, partial
                     CDS, len: >278 aa. Highly similar to Streptomyces griseus
                     TR:P72449 (EMBL:X95596) dehydrogenase (517 aa), fasta
                     scores opt: 1311 z-score: 1471.3 E(): 0 74.0% identity in
                     269 aa overlap and Synechocystis sp. (strain PCC 6803)
                     SW:CRTI_SYNY3 (EMBL:X62574) phytoene dehydrogenase (EC
                     1.3.-.-) (phytoene desaturase) (427 aa), fasta scores opt:
                     219 z-score: 250.2 E(): 1.4e-06 27.6% identity in 254 aa
                     overlap."
                     /product="dehydrogenase"
                     /protein_id="NP_733493.1"
                     /sec_met_domain="DAO (E-value: 3.1e-12, bitscore: 45.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVRRTAAARRGRDRKAEIVFPAPGADRFGRGDEPSVAVIGGGIA
                     GLAAATLMAERGARVTLYEKEDAVGGRLSGRRTTLADGSAVTMTRGFHAFFRQYYNLRG
                     LLRRTDPGLDRLTPLPDYPLRHSGGLTDGFARVPRTPPLSAIGFVALSPTFGWRDLAAM
                     DPRAALPLLDVRVPQVYERFDGVTATAFLESVRFPEAAHHLAFEVFSRSFFADPRRLSA
                     AELLLMFHIYFLGSSEGLLFDVPVEPFPQALWNPLGDYLRRLGADVRTGTPVHGILPRA
                     DGGADVLTDTGADRHQAVVLALDTAGLRQTVAASPGLGTDTWRDGIAALRTAPPFLVSR
                     LWLDRPVDADRPGFLGTSGYGGLDNVSVLERYEGEAARWAARTGGSVVELHAYAVDPAA
                     EPKEVQDELVDRLHQAYPETREARVVDARHEWRADCPMFEVGSHRRRPTVRTPHPWLTL
                     AGDGIRCDLPVALMERAATTGFLAANALLADRGVRGQVLWTVPRTGRSPVLRAFGAVAG
                     HRSAP"
     PFAM_domain     complement(14860..16191)
                     /aSDomain="Amino_oxidase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01593.27"
                     /db_xref="GO:0016491"
                     /description="Flavin containing amine oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0189_0066"
                     /evalue="7.90E-33"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO0189"
                     /locus_tag="SCO0189"
                     /protein_end="487"
                     /protein_start="43"
                     /score="114.5"
                     /tool="antismash"
                     /translation="IAGLAAATLMAERGARVTLYEKEDAVGGRLSGRRTTLADGSAVTM
                     TRGFHAFFRQYYNLRGLLRRTDPGLDRLTPLPDYPLRHSGGLTDGFARVPRTPPLSAIG
                     FVALSPTFGWRDLAAMDPRAALPLLDVRVPQVYERFDGVTATAFLESVRFPEAAHHLAF
                     EVFSRSFFADPRRLSAAELLLMFHIYFLGSSEGLLFDVPVEPFPQALWNPLGDYLRRLG
                     ADVRTGTPVHGILPRADGGADVLTDTGADRHQAVVLALDTAGLRQTVAASPGLGTDTWR
                     DGIAALRTAPPFLVSRLWLDRPVDADRPGFLGTSGYGGLDNVSVLERYEGEAARWAART
                     GGSVVELHAYAVDPAAEPKEVQDELVDRLHQAYPETREARVVDARHEWRADCPMFEVGS
                     HRRRPTVRTPHPWLTLAGDGIRCDLPVALMERAATTGFLAANALL"
     misc_feature    15485..15617
                     /note="665 (-1) 36793 36925 overlap with cosmid StJ1"
     misc_feature    complement(15485..15617)
                     /gene_synonym="crtU; SCJ1.38c"
                     /locus_tag="SCO0189"
                     /note="overlap with StJ12"
     gene            complement(16317..17057)
                     /db_xref="GeneID:1095614"
                     /gene_synonym="crtT; SCJ12.02c"
                     /locus_tag="SCO0190"
     CDS             complement(16317..17057)
                     /codon_start=1
                     /db_xref="GeneID:1095614"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="crtT; SCJ12.02c"
                     /locus_tag="SCO0190"
                     /note="SCJ12.02c, crtT, probable methyltransferase, len:
                     246 aa. Shares a high level of sequence similarity with
                     Streptomyces griseus TR:P72450 (EMBL:X95596)
                     methyltransferase (242 aa), fasta scores opt: 984 z-score:
                     1164.2 E(): 0 65.0% identity in 234 aa overlap. Contains a
                     Pfam match to entry PF01209 Ubie_methyltran, ubiE/COQ5
                     methyltransferase family"
                     /product="methyltransferase"
                     /protein_id="NP_624525.1"
                     /transl_table=11
                     /translation="MTLLRDHDLARAFDHASHTYDGLTALNPGYRTGLLRSARRLALPA
                     DGAGLHLLDLGCGTGASTRALLRAAPRARITAVDASAGMLRRALVKPWPARVRFLHLTA
                     EEFATTREDEGPFDAVFAAYLFRNVTDPDAVLRAVRQLLRPGGRFAAHEYSLSGSPGHR
                     ALWSAVCRGVVIPAGTLTGDRTLYRHLRRSVVAFDTAPEFAARLTRAGLTSVRVAPVAG
                     WQTGIVHTFLARNGGPTTTEERVL"
     regulatory      complement(16329..16334)
                     /gene_synonym="crtT; SCJ12.02c"
                     /locus_tag="SCO0190"
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(16356..17057)
                     /gene_synonym="crtT; SCJ12.02c"
                     /locus_tag="SCO0190"
                     /note="Pfam match to entry PF01209 Ubie_methyltran,
                     ubiE/COQ5 methyltransferase family, score -45.20, E-value
                     1.1e-08"
     PFAM_domain     complement(16401..17042)
                     /aSDomain="Ubie_methyltran"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01209.21"
                     /description="ubiE/COQ5 methyltransferase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0190_0067"
                     /evalue="1.90E-19"
                     /label="SCO0190"
                     /locus_tag="SCO0190"
                     /protein_end="219"
                     /protein_start="5"
                     /score="70.1"
                     /tool="antismash"
                     /translation="DHDLARAFDHASHTYDGLTALNPGYRTGLLRSARRLALPADGAGL
                     HLLDLGCGTGASTRALLRAAPRARITAVDASAGMLRRALVKPWPARVRFLHLTAEEFAT
                     TREDEGPFDAVFAAYLFRNVTDPDAVLRAVRQLLRPGGRFAAHEYSLSGSPGHRALWSA
                     VCRGVVIPAGTLTGDRTLYRHLRRSVVAFDTAPEFAARLTRAGLTSVRVAP"
     gene            complement(17054..18271)
                     /db_xref="GeneID:1095615"
                     /gene_synonym="crtY; SCJ12.03c"
                     /locus_tag="SCO0191"
     CDS             complement(17054..18271)
                     /codon_start=1
                     /db_xref="GeneID:1095615"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /gene_synonym="crtY; SCJ12.03c"
                     /locus_tag="SCO0191"
                     /note="SCJ12.03c, crtY, probable lycopene cyclase, len: 405
                     aa. Highly similar to Streptomyces griseus TR:P72451
                     (EMBL:X95596) lycopene cyclase (418 aa), fasta scores opt:
                     1426 z-score: 1602.7 E(): 0 56.3% identity in 396 aa
                     overlap"
                     /product="lycopene cyclase"
                     /protein_id="NP_624526.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 3.1e-111,
                     bitscore: 370.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPRSAQDSDVLVIGGGAAGLSLAHRLTENGTAPAMTLVEPPDGP
                     LRPAERTWCYWGAAADGLEEAVGASWSVLRLHGADGGSVTVDPAPFTYRMVRSADFERM
                     VHGRLARTDGARLLRGTAESVRAVPAGTEVRCTLPGGRPLTLYARRVFDSRPLPELPPA
                     RTCLLQHFRGWFVHTRTDRFDPAVADLMDFRVPQPAHGLAFGYVLPLAPDRALVEYTEF
                     SRAPLTTEAYESALGHYCRDILGLGELTVERTEQGVIPMTDARFPGRAGPAVYRIGTAG
                     GATRPATGYTFAAVQRHSGAIAAALRDGHDRVPAPHGRRARAMDAVLLRALDTGRIDGP
                     RFFTDLFRRVPAERLLRFLDGTTSLREEWGIGLRTPVRPMLRTAAEVPFLPRRSQPLAR
                     TGGNNR"
     PFAM_domain     complement(17120..18244)
                     /aSDomain="Lycopene_cycl"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05834.15"
                     /description="Lycopene cyclase protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0191_0068"
                     /evalue="5.20E-130"
                     /label="SCO0191"
                     /locus_tag="SCO0191"
                     /protein_end="384"
                     /protein_start="9"
                     /score="434.0"
                     /tool="antismash"
                     /translation="DVLVIGGGAAGLSLAHRLTENGTAPAMTLVEPPDGPLRPAERTWC
                     YWGAAADGLEEAVGASWSVLRLHGADGGSVTVDPAPFTYRMVRSADFERMVHGRLARTD
                     GARLLRGTAESVRAVPAGTEVRCTLPGGRPLTLYARRVFDSRPLPELPPARTCLLQHFR
                     GWFVHTRTDRFDPAVADLMDFRVPQPAHGLAFGYVLPLAPDRALVEYTEFSRAPLTTEA
                     YESALGHYCRDILGLGELTVERTEQGVIPMTDARFPGRAGPAVYRIGTAGGATRPATGY
                     TFAAVQRHSGAIAAALRDGHDRVPAPHGRRARAMDAVLLRALDTGRIDGPRFFTDLFRR
                     VPAERLLRFLDGTTSLREEWGIGLRTPVRPMLRTA"
     gene            complement(18542..19792)
                     /db_xref="GeneID:1095616"
                     /gene_synonym="SCJ12.04c"
                     /locus_tag="SCO0192"
     CDS             complement(18542..19792)
                     /codon_start=1
                     /db_xref="GeneID:1095616"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCJ12.04c"
                     /locus_tag="SCO0192"
                     /note="SCJ12.04c, possible oxidoreductase, len: 416 aa.
                     Similar to many protoporphyrinogen oxidases including:
                     Propionibacterium freudenreichii shermanii SW:PPOX_PROFR
                     (EMBL:D85417) HemY (527 aa), fasta scores opt: 228 z-score:
                     249.0 E(): 1.6e-06 26.8% identity in 504 aa overlap and
                     Bacillus subtilis SW:PPOX_BACSU (EMBL; M97208) HemY (470
                     aa), fasta scores opt: 209 z-score: 229.3 E(): 2.1e-05
                     25.7% identity in 311 aa overlap. Contains a Pfam match to
                     entry PF01593 Amino_oxidase"
                     /product="oxidoreductase"
                     /protein_id="NP_624527.1"
                     /sec_met_domain="DAO (E-value: 4.4e-09, bitscore: 35.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDGQHRAADAVVVGAGLAGLACALDLCRAGWRVALLEASDGVGG
                     RMRTDRRDGFLLDRGFQVFNTSYPQVKRRMELKSLRLRPFTAGVVAHTSNGPVRLADPT
                     REPRAAGTLLPGRALPARDLAALAALTARDAVLPVAVTRRRRDRPTSAALSRVGLSDAA
                     IAGILRPFLSGVFLEDRLETSARFFHLVWRSMVRGSLCLPAEGIGAVPAQLADGLPDGV
                     LRLGTPVAEITDAGVLLGDGGEVPARVVVVATDPATAAGLLPDLTVPDTRTVTTYYHAT
                     DSPPTAEPILMVDSTGAILNTCVLSQVAPTYAPPGTGLVSTSVLGTDPPGRAQAVLRRL
                     AELYGTDTSGWEQVAARTVDGALPAMLPPWPLSRTTRIGPGRYVCGDHRATGSVQGALA
                     SGTRAAREVRADREPQR"
     misc_feature    complement(18566..19741)
                     /gene_synonym="SCJ12.04c"
                     /locus_tag="SCO0192"
                     /note="Pfam match to entry PF01593 Amino_oxidase, score
                     -105.60, E-value 0.0012"
     PFAM_domain     complement(18569..19741)
                     /aSDomain="Amino_oxidase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01593.27"
                     /db_xref="GO:0016491"
                     /description="Flavin containing amine oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0192_0069"
                     /evalue="2.40E-50"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO0192"
                     /locus_tag="SCO0192"
                     /protein_end="408"
                     /protein_start="17"
                     /score="172.3"
                     /tool="antismash"
                     /translation="LAGLACALDLCRAGWRVALLEASDGVGGRMRTDRRDGFLLDRGFQ
                     VFNTSYPQVKRRMELKSLRLRPFTAGVVAHTSNGPVRLADPTREPRAAGTLLPGRALPA
                     RDLAALAALTARDAVLPVAVTRRRRDRPTSAALSRVGLSDAAIAGILRPFLSGVFLEDR
                     LETSARFFHLVWRSMVRGSLCLPAEGIGAVPAQLADGLPDGVLRLGTPVAEITDAGVLL
                     GDGGEVPARVVVVATDPATAAGLLPDLTVPDTRTVTTYYHATDSPPTAEPILMVDSTGA
                     ILNTCVLSQVAPTYAPPGTGLVSTSVLGTDPPGRAQAVLRRLAELYGTDTSGWEQVAAR
                     TVDGALPAMLPPWPLSRTTRIGPGRYVCGDHRATGSVQGALASGTRAAREV"
     regulatory      complement(19797..19801)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(20026..21030)
                     /db_xref="GeneID:1095617"
                     /gene_synonym="SCJ12.05c"
                     /locus_tag="SCO0193"
     CDS             complement(20026..21030)
                     /codon_start=1
                     /db_xref="GeneID:1095617"
                     /gene_synonym="SCJ12.05c"
                     /locus_tag="SCO0193"
                     /note="SCJ12.05c, possible DNA-binding regulator, len:334
                     aa. Some similarity to Myxococcus xanthus TR:Q50900
                     (EMBL:Z21955) regulatory protein (299 aa), fasta scores
                     opt: 121 z-score: 141.6 E(): 1.6 32.4% identity in 281 aa
                     overlap and Myxococcus xanthus TR:Q50899 (EMBL:Z21955)
                     regulatory protein (288 aa), fasta scores opt: 118 z-score:
                     138.5 E() 2.4 26.9% identity in 279 aa overlap. Contains a
                     possible helix-turn-helix motif between aa's 23..44."
                     /product="DNA-binding regulator"
                     /protein_id="NP_624528.1"
                     /transl_table=11
                     /translation="MNAYTGDGDEPVDDGGPRRGGLTTGEVARRLGVAPTTVRTWDRRY
                     GLGPDAHVDGRHRRWTAADLARLERMCALTATGLPPAEAARLARSEERPTAAGPRNTDA
                     ARRAPTGRRSRAGSGLQLGDVRQECRGIARAALRLDASALDELLLAAIAEHGLVAAWTE
                     VIVPTLQAVGRKWETSGEKYVEVEHFLSWHVSGALRRAAPPAVEDRPGSTTVLACVPGE
                     NHTLPLEVLSAALTERGVPVRMFGGALPVESLVAAVRRTGPAAVGLWSQSRTTASRPLA
                     QHVAAMEWGVRGARRRPVVLTLGPGWAGQAVAGLARPSGLAEAVAALEPSVYP"
     PFAM_domain     complement(20431..20643)
                     /aSDomain="B12-binding_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02607.20"
                     /description="B12 binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0193_0071"
                     /evalue="1.10E-07"
                     /label="SCO0193"
                     /locus_tag="SCO0193"
                     /protein_end="200"
                     /protein_start="129"
                     /score="32.4"
                     /tool="antismash"
                     /translation="RGIARAALRLDASALDELLLAAIAEHGLVAAWTEVIVPTLQAVGR
                     KWETSGEKYVEVEHFLSWHVSGALRR"
     PFAM_domain     complement(20761..20964)
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13411.9"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0006355"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0193_0070"
                     /evalue="1.90E-12"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO0193"
                     /locus_tag="SCO0193"
                     /protein_end="90"
                     /protein_start="22"
                     /score="47.1"
                     /tool="antismash"
                     /translation="TTGEVARRLGVAPTTVRTWDRRYGLGPDAHVDGRHRRWTAADLAR
                     LERMCALTATGLPPAEAARLARS"
     regulatory      21178..21183
                     /regulatory_class="ribosome_binding_site"
     gene            21191..21799
                     /db_xref="GeneID:1095618"
                     /gene_synonym="SCJ12.06"
                     /locus_tag="SCO0194"
     CDS             21191..21799
                     /codon_start=1
                     /db_xref="GeneID:1095618"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /gene_synonym="SCJ12.06"
                     /locus_tag="SCO0194"
                     /note="SCJ12.06, possible sigma factor, len: 202 aa.
                     Similar to many including: Rhodobacter sphaeroide TR:O33546
                     (EMBL; U11283) RpoE homologue (168 aa), fasta scores opt:
                     291 z-score: 373.4 E(): 1.9e-13 35.4% identity in 161 aa
                     overlap and Streptomyces coelicolor TR:O54163 (EMBL;
                     AL021411) sigma factor SC7H1.04 (200 aa), fasta scores opt:
                     255 z-score: 327.4 E(): 7.1e-11 33.7% identity in 184 aa
                     overlap. Contains a PS01063 Sigma-70 factors ECF subfamily
                     signature and a Pfam match to entry PF00776 Sigma70_ECF,
                     Sigma-70 factor (ECF subfamily). Contains a possible
                     helix-turn-helix motif between aa's 162..183."
                     /product="sigma factor"
                     /protein_id="NP_624529.1"
                     /transl_table=11
                     /translation="MNTRTRPTTTPVPPVEETRYEEELAHGLVKADEDAFAAIYRRWGS
                     LVHTLATRSLGDAHEAEDVTQQVFVGAWRGRHGFRPERGTLGAWLVGITRRKVVDALAA
                     RTRRLSLVESAGQDITPARLVQPALDEVLDRVLLVEALSRLPQAQRDVLCMAFYEDLTQ
                     AQIAERTGVPLGTVKSHARRGLHRLRTAVGPGAAHDTCV"
     aSDomain        21290..21763
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO0194_0004"
                     /evalue="5.20E-25"
                     /identifier="TIGR02937"
                     /label="SCO0194"
                     /locus_tag="SCO0194"
                     /protein_end="191"
                     /protein_start="33"
                     /score="85.9"
                     /tool="antismash"
                     /translation="DAFAAIYRRWGSLVHTLATRSLGDAHEAEDVTQQVFVGAWRGRHG
                     FRPERGTLGAWLVGITRRKVVDALAARTRRLSLVESAGQDITPARLVQPALDEVLDRVL
                     LVEALSRLPQAQRDVLCMAFYEDLTQAQIAERTGVPLGTVKSHARRGLHRLRTA"
     PFAM_domain     21305..21511
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04542.17"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006352"
                     /db_xref="GO:0006355"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0194_0072"
                     /evalue="5.00E-18"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006352: DNA-templated transcription
                     initiation"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO0194"
                     /locus_tag="SCO0194"
                     /protein_end="107"
                     /protein_start="38"
                     /score="64.8"
                     /tool="antismash"
                     /translation="IYRRWGSLVHTLATRSLGDAHEAEDVTQQVFVGAWRGRHGFRPER
                     GTLGAWLVGITRRKVVDALAARTR"
     misc_feature    21335..21541
                     /gene_synonym="SCJ12.06"
                     /locus_tag="SCO0194"
                     /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70
                     factor (ECF subfamily), score 47.10, E-value 3.8e-10"
     misc_feature    21371..21469
                     /gene_synonym="SCJ12.06"
                     /locus_tag="SCO0194"
                     /note="PS01063 Sigma-70 factors ECF subfamily signature,
                     info count = 32.1"
     PFAM_domain     21611..21757
                     /aSDomain="Sigma70_r4"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04545.19"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006352"
                     /db_xref="GO:0006355"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0194_0073"
                     /evalue="4.70E-17"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006352: DNA-templated transcription
                     initiation"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO0194"
                     /locus_tag="SCO0194"
                     /protein_end="189"
                     /protein_start="140"
                     /score="61.4"
                     /tool="antismash"
                     /translation="ALSRLPQAQRDVLCMAFYEDLTQAQIAERTGVPLGTVKSHARRGL
                     HRLR"
     regulatory      21893..21897
                     /regulatory_class="ribosome_binding_site"
     gene            21908..22594
                     /db_xref="GeneID:1095619"
                     /gene_synonym="SCJ12.07"
                     /locus_tag="SCO0195"
     CDS             21908..22594
                     /codon_start=1
                     /db_xref="GeneID:1095619"
                     /gene_synonym="SCJ12.07"
                     /locus_tag="SCO0195"
                     /note="SCJ12.07, possible lipoprotein, len: 228 aa.
                     Contains an N-terminal signal sequence and a PS00013
                     Prokaryotic membrane lipoprotein lipid attachment site."
                     /product="lipoprotein"
                     /protein_id="NP_624530.1"
                     /transl_table=11
                     /translation="MMSRTTIAVAGSAGACALAPTAPAATAAPEQAQDTGLVSVFHGIP
                     GTTVDVFANGDEPLGDFQPGTVTEGGNTTVAAHLSADGKPRLTTFTDDVSKTDAGRSRL
                     TVRHVAAAPAVDVRAGGHPLFTGLANPDEDTALVEAGIVNADVVLAGTETVVVGPAGLD
                     LKEGTTNVVYAWGSAEDQTLALPGQAFGGMDSTPLAVHPGAGGTAATPNASDRWRARAA
                     TPARSR"
     misc_feature    21923..21955
                     /gene_synonym="SCJ12.07"
                     /locus_tag="SCO0195"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site."
     PFAM_domain     22103..22258
                     /aSDomain="DUF4397"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF14344.9"
                     /description="Domain of unknown function (DUF4397)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0195_0074"
                     /evalue="4.60E-08"
                     /label="SCO0195"
                     /locus_tag="SCO0195"
                     /protein_end="117"
                     /protein_start="65"
                     /score="33.9"
                     /tool="antismash"
                     /translation="TVTEGGNTTVAAHLSADGKPRLTTFTDDVSKTDAGRSRLTVRHVA
                     AAPAVDV"
     regulatory      22705..22710
                     /regulatory_class="ribosome_binding_site"
     gene            22716..23120
                     /db_xref="GeneID:1095620"
                     /gene_synonym="SCJ12.08"
                     /locus_tag="SCO0196"
     CDS             22716..23120
                     /codon_start=1
                     /db_xref="GeneID:1095620"
                     /gene_synonym="SCJ12.08"
                     /locus_tag="SCO0196"
                     /note="SCJ12.08, unknown, len:134 aa. Shares a low level of
                     similarity with Mycobacterium tuberculosis TR:O53597 (EMBL;
                     AL021426) hypothetical 24.0 KD protein MTV028.10C (224 aa),
                     fasta scores opt: 119 z-score: 159.2 E(): 0.1 32.8%
                     identity in 116 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_624531.1"
                     /transl_table=11
                     /translation="MGHVHPSHLVELALGHASGEADVGALRHAASCPRCREELLRLTRV
                     VTAARGAEASDLPVPPPERVWQRIALEVLPETDRVPRLRESSAHGSADERVRGSQRRWT
                     DHAGEGLLGLALAIAVLLLRRWRIRAGSGN"
     gene            complement(23252..23692)
                     /db_xref="GeneID:1095621"
                     /gene_synonym="SCJ12.09c"
                     /locus_tag="SCO0197"
     CDS             complement(23252..23692)
                     /codon_start=1
                     /db_xref="GeneID:1095621"
                     /gene_synonym="SCJ12.09c"
                     /locus_tag="SCO0197"
                     /note="SCJ12.09c, hypothetical protein, len: 146 aa. Some
                     similarity to Mycobacterium tuberculosis TR:O53625 (EMBL;
                     AL021428) hypothetical 16.6 KD protein (152 aa), fasta
                     scores opt: 291 z-score: 377.8 E(): 1.1e-13 42.9% identity
                     in 133 aa overlap. Also similar to TR:Q9RI34
                     (EMBL:AL109989) S. coelicolor SCJ12.26 (137 aa), fasta
                     scores: opt: 524 z-score: 568.0 E(): 2.2e-26 62.2% identity
                     in 135 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_624532.1"
                     /transl_table=11
                     /translation="MYRNDGFRELNRQESLQRLANAPVGRIVHTRDALPAVLPVNFVLE
                     KSGAVLLRTSASSELVRAVDGAVVAFEADEVDAVTHSGWSVVVTGLASVVTDPGEHEQL
                     VRTGPRSWVPWPVEVFVRIAPDLVSGRELVGGRTLYGLDPPT"
     PFAM_domain     complement(23300..23659)
                     /aSDomain="Pyridox_ox_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF12900.10"
                     /description="Pyridoxamine 5'-phosphate oxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0197_0075"
                     /evalue="8.90E-26"
                     /label="SCO0197"
                     /locus_tag="SCO0197"
                     /protein_end="131"
                     /protein_start="11"
                     /score="90.7"
                     /tool="antismash"
                     /translation="RQESLQRLANAPVGRIVHTRDALPAVLPVNFVLEKSGAVLLRTSA
                     SSELVRAVDGAVVAFEADEVDAVTHSGWSVVVTGLASVVTDPGEHEQLVRTGPRSWVPW
                     PVEVFVRIAPDLVSGR"
     gene            complement(24225..25091)
                     /db_xref="GeneID:1095622"
                     /gene_synonym="SCJ12.10c"
                     /locus_tag="SCO0198"
     CDS             complement(24225..25091)
                     /codon_start=1
                     /db_xref="GeneID:1095622"
                     /gene_synonym="SCJ12.10c"
                     /locus_tag="SCO0198"
                     /note="SCJ12.10c, unknown, len: 288 aa. Similar to several
                     hypothetical proteins including: Mycobacterium tuberculosis
                     SW:YW12_MYCTU (EMBL; Z74025) hypothetical 30.9 KD protein
                     MTCY39.12 (295 aa), fasta scores opt: 363 z-score: 441.0
                     E(): 3.3e-17 32.3% identity in 288 aa overlap and
                     Mycobacterium tuberculosis TR:O06189 (EMBL; Z95387)
                     hypothetical 31.7 KD protein MTCY1A10.09C (297 aa), fasta
                     scores opt: 336 z-score: 408.6 E(): 2.1e-15 29.3% identity
                     in 294 aa overlap. Also highly similar to S. coelicolor
                     hypothetical proteins (AL109962) SCJ1.29c (283 aa), fasta
                     scores opt: 1161 z-score: 1097.2 E(): 0 63.5% identity in
                     288 aa overlap and SCJ1.16c (294 aa), fasta scores opt:892
                     z-score: 844.7 E():0 50.3% identity in 296 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_624533.1"
                     /transl_table=11
                     /translation="MYLPMVVGVDGSESSLGAVDWAADEAALHEVPLRIVHAYRWDRYE
                     GASLARELGKPSGHVTTDDILAVATRRARRHHPDLAVTTEATAEEPEYVLLREARNASA
                     VILGTRGRGELAGLLLGSVSLTVATMSDCPVVVTRGDHDDRAAGGGRRGRIVVGVADAP
                     TAAVRFACEEARRRGAALDAVRAWRCPTHDTVDHPLLAGTPERLHEERAAKELEAALAD
                     APADVRLRRRTAEGPGSRVLSAASHEADLLVVGRRRPGQFGHRLGRVAHTLLHHSACPV
                     AVVPDTT"
     PFAM_domain     complement(24237..24632)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0198_0077"
                     /evalue="1.40E-19"
                     /label="SCO0198"
                     /locus_tag="SCO0198"
                     /protein_end="285"
                     /protein_start="153"
                     /score="71.1"
                     /tool="antismash"
                     /translation="RIVVGVADAPTAAVRFACEEARRRGAALDAVRAWRCPTHDTVDHP
                     LLAGTPERLHEERAAKELEAALADAPADVRLRRRTAEGPGSRVLSAASHEADLLVVGRR
                     RPGQFGHRLGRVAHTLLHHSACPVAVVP"
     PFAM_domain     complement(24675..25091)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0198_0076"
                     /evalue="6.10E-25"
                     /label="SCO0198"
                     /locus_tag="SCO0198"
                     /protein_end="139"
                     /protein_start="0"
                     /score="88.5"
                     /tool="antismash"
                     /translation="MYLPMVVGVDGSESSLGAVDWAADEAALHEVPLRIVHAYRWDRYE
                     GASLARELGKPSGHVTTDDILAVATRRARRHHPDLAVTTEATAEEPEYVLLREARNASA
                     VILGTRGRGELAGLLLGSVSLTVATMSDCPVVVTR"
     gene            complement(25097..26119)
                     /db_xref="GeneID:1095623"
                     /gene_synonym="SCJ12.11c"
                     /locus_tag="SCO0199"
     CDS             complement(25097..26119)
                     /NRPS_PKS="Domain: PKS_ER (15-227). E-value: 3.8e-12.
                     Score: 37.9. Matches aSDomain:
                     nrpspksdomains_SCO0199_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:1095623"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCJ12.11c"
                     /locus_tag="SCO0199"
                     /note="SCJ12.11c, probable alcohol dehydrogenase, len: 340
                     aa. Highly similar to many e.g. Bacillus stearothermophilus
                     SW:ADH3_BACST (EMBL; Z27089) alcohol dehydrogenase (EC
                     1.1.1.1) (ADH-HT) (339 aa), fasta scores opt: 1281 z-score:
                     1383.7 E(): 0 55.2% identity in 337 aa overlap. Contains a
                     PS00059 Zinc-containing alcohol dehydrogenases signature
                     and a Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases."
                     /product="alcohol dehydrogenase"
                     /protein_id="NP_624534.1"
                     /sec_met_domain="ADH_N (E-value: 1.9e-31, bitscore: 107.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.5e-28, bitscore:
                     96.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAAVVREFGKPLVIEDRPDPEPGPGQVLVAVEASGLCHTDIHAA
                     HGDWPVKPTPPFVPGHEGVGLVEKLGDGVTHLAVGQRVAVPWLGKACGRCEHCRSGWET
                     LCEDQVNTGYGCDGGYAEKMLAWADFAQPVPEGVSALDAAPLTCAGVTTYKALKVAEVG
                     PAQLVAVSGVGGLGHLAVQYAKIAGARVVAIDVTDDKLQLARELGADLVIDARTQDVGA
                     ELKRHGGAHAALALAVNPAAFQAVNSGLRRGGKLVMVALPAHGTLQVPIFDTVLNGTSV
                     IGSIVGTRQDLAEVFQLHAEGRTKVIRETRPLAAVNDCIDEVLGGQVKARIVFDLNAGG
                     "
     regulatory      complement(25101..25105)
                     /gene_synonym="SCJ12.11c"
                     /locus_tag="SCO0199"
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(25115..26113)
                     /gene_synonym="SCJ12.11c"
                     /locus_tag="SCO0199"
                     /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases, score 359.60, E-value 3.2e-104"
     PFAM_domain     complement(25226..25597)
                     /aSDomain="ADH_zinc_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00107.29"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0199_0079"
                     /evalue="1.60E-27"
                     /label="SCO0199"
                     /locus_tag="SCO0199"
                     /protein_end="298"
                     /protein_start="174"
                     /score="96.2"
                     /tool="antismash"
                     /translation="GLGHLAVQYAKIAGARVVAIDVTDDKLQLARELGADLVIDARTQD
                     VGAELKRHGGAHAALALAVNPAAFQAVNSGLRRGGKLVMVALPAHGTLQVPIFDTVLNG
                     TSVIGSIVGTRQDLAEVFQL"
     aSDomain        complement(25439..26074)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO0199_PKS_ER.1"
                     /evalue="3.80E-12"
                     /label="SCO0199_PKS_ER.1"
                     /locus_tag="SCO0199"
                     /protein_end="227"
                     /protein_start="15"
                     /score="37.9"
                     /tool="antismash"
                     /translation="EDRPDPEPGPGQVLVAVEASGLCHTDIHAAHGDWPVKPTPPFVPG
                     HEGVGLVEKLGDGVTHLAVGQRVAVPWLGKACGRCEHCRSGWETLCEDQVNTGYGCDGG
                     YAEKMLAWADFAQPVPEGVSALDAAPLTCAGVTTYKALKVAEVGPAQLVAVSGVGGLGH
                     LAVQYAKIAGARVVAIDVTDDKLQLARELGADLVIDARTQDVGAELKRH"
     PFAM_domain     complement(25736..26047)
                     /aSDomain="ADH_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08240.15"
                     /description="Alcohol dehydrogenase GroES-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0199_0078"
                     /evalue="4.70E-31"
                     /label="SCO0199"
                     /locus_tag="SCO0199"
                     /protein_end="128"
                     /protein_start="24"
                     /score="107.0"
                     /tool="antismash"
                     /translation="PGQVLVAVEASGLCHTDIHAAHGDWPVKPTPPFVPGHEGVGLVEK
                     LGDGVTHLAVGQRVAVPWLGKACGRCEHCRSGWETLCEDQVNTGYGCDGGYAEKMLAWA
                     "
     misc_feature    complement(25898..25942)
                     /gene_synonym="SCJ12.11c"
                     /locus_tag="SCO0199"
                     /note="PS00059 Zinc-containing alcohol dehydrogenases
                     signature."
     regulatory      complement(26127..26132)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(26158..27063)
                     /db_xref="GeneID:1095624"
                     /gene_synonym="SCJ12.12c"
                     /locus_tag="SCO0200"
     CDS             complement(26158..27063)
                     /codon_start=1
                     /db_xref="GeneID:1095624"
                     /gene_synonym="SCJ12.12c"
                     /locus_tag="SCO0200"
                     /note="SCJ12.12c, unknown, len: 301 aa. Similar to several
                     hypothetical proteins including: Mycobacterium tuberculosis
                     SW:YW23_MYCTU (EMBL; Z74025) hypothetical 33.9 KD protein
                     MTCY39.23C (317 aa), fasta scores opt: 380 z-score: 447.3
                     E(): 1.5e-17 33.5% identity in 316 aa overlap and S.
                     coelicolor (EMBL;AL109962) SCJ1.30c (328 aa)fasta scores
                     opt: 1274 z-score: 1163.7 E():0 65.3% identity in 300 aa
                     overlap. Contains 2x Pfam match to entry PF00582 Usp,
                     Universal stress protein family."
                     /product="hypothetical protein"
                     /protein_id="NP_624535.1"
                     /transl_table=11
                     /translation="MARTITVGLDGSPESRAAAEWAAREGTLRRVPVRLLHVWQPVPEP
                     MAQAPLLGAETHQHWTERIPRDTAEGLRLRHPGVEVTTEQATGNPADALLAGTLDAELL
                     VLGSRALSGLTGFLVGSVGQSVIARTETPVILVRAGEQAADEHLKDPTGIPSAATGFRP
                     VVVGLDTGSPDEAVLSFAFEEARRRRAPLTAVRAWNLPSSYTYSIAAGFDPREELARAQ
                     AEALGEALLPWREKYPDVEVTETCRLGSPAEHLIDAARDASLVVVGRRIRRSPFGVHIG
                     AVAHAVMHHATTPVAVVAHD"
     misc_feature    complement(26170..26487)
                     /gene_synonym="SCJ12.12c"
                     /locus_tag="SCO0200"
                     /note="Pfam match to entry PF00582 Usp, Universal stress
                     protein family, score 47.30, E-value 3.4e-10"
     PFAM_domain     complement(26170..26583)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0200_0081"
                     /evalue="1.70E-19"
                     /label="SCO0200"
                     /locus_tag="SCO0200"
                     /protein_end="298"
                     /protein_start="160"
                     /score="70.9"
                     /tool="antismash"
                     /translation="FRPVVVGLDTGSPDEAVLSFAFEEARRRRAPLTAVRAWNLPSSYT
                     YSIAAGFDPREELARAQAEALGEALLPWREKYPDVEVTETCRLGSPAEHLIDAARDASL
                     VVVGRRIRRSPFGVHIGAVAHAVMHHATTPVAVV"
     PFAM_domain     complement(26650..27063)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0200_0080"
                     /evalue="1.60E-25"
                     /label="SCO0200"
                     /locus_tag="SCO0200"
                     /protein_end="138"
                     /protein_start="0"
                     /score="90.4"
                     /tool="antismash"
                     /translation="MARTITVGLDGSPESRAAAEWAAREGTLRRVPVRLLHVWQPVPEP
                     MAQAPLLGAETHQHWTERIPRDTAEGLRLRHPGVEVTTEQATGNPADALLAGTLDAELL
                     VLGSRALSGLTGFLVGSVGQSVIARTETPVILVR"
     misc_feature    complement(26653..26964)
                     /gene_synonym="SCJ12.12c"
                     /locus_tag="SCO0200"
                     /note="Pfam match to entry PF00582 Usp, Universal stress
                     protein family, score 27.00, E-value 0.00011"
     misc_feature    27148..27162
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: strong, score: 28.31"
                     /tool="antismash"
     gene            complement(27216..27887)
                     /db_xref="GeneID:1095625"
                     /gene_synonym="SCJ12.13c"
                     /locus_tag="SCO0201"
     CDS             complement(27216..27887)
                     /codon_start=1
                     /db_xref="GeneID:1095625"
                     /gene_synonym="SCJ12.13c"
                     /locus_tag="SCO0201"
                     /note="SCJ12.13c, possible integral membrane protein, len:
                     223 aa. Contains potential membrane spanning hydrophobic
                     domains."
                     /product="hypothetical protein"
                     /protein_id="NP_624536.1"
                     /transl_table=11
                     /translation="MSGTNRILSEGVTVMAMHQSTHRGSGFHLPSSRRNGAVSVPGAAD
                     SVEAGALTARAFVFASARVLMGFVFLWAFLDKTFGFGYATASGKGWIDGGSPTEGFLGH
                     VAVGPMESTFHSWAGAAWADWLFMLGLLGVGLALTAGVALRPAAVAGTVMMALMWAAEW
                     PPAKHLSDGSASMSTNPFADYHVLYAVLLIALAAVSAGDALGLGRLWARLPIVRDHAWL
                     R"
     PFAM_domain     complement(27408..27704)
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07681.15"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0201_0082"
                     /evalue="4.70E-05"
                     /label="SCO0201"
                     /locus_tag="SCO0201"
                     /protein_end="160"
                     /protein_start="61"
                     /score="24.0"
                     /tool="antismash"
                     /translation="ARVLMGFVFLWAFLDKTFGFGYATASGKGWIDGGSPTEGFLGHVA
                     VGPMESTFHSWAGAAWADWLFMLGLLGVGLALTAGVALRPAAVAGTVMMALMWA"
ORIGIN
        1 gttcgtcctc gtcgtaggag gcgaaggacg tgtccaggac gacgcgtccc atccgggtgg
       61 gcagcccccg gggggtgaac cgggtgacat tgatcgtacg accacagcgt gtgtgcagtt
      121 tcatctcgtc tcccgccggg tttcgccggt cggcctcatt gccgtcggcg ggtcctggtc
      181 cggtctcgcg ccggccgggg cgcgtgtctc cgggcccagg ggccctgcct cgtgcgccgt
      241 gtgagcacac gtgcctcaag agccggacac ggaagtgata cgtcgtcctg tcagacgttc
      301 cgtctccacg gcaagccaca tggtgcgccg tccgccggcc catggctcgg tgtgcgcctt
      361 ctccgccagt cggcgtacct cctccgggtc cgtcacggcc ctgcaacgac cgaccgcgag
      421 gacactccat ccctgactca tgggatcgtc gatgtggtcg acctcgaagg cgacctcgct
      481 gtccacggcc gcggcagtgg ccgcgtcggg gtcggtgcgg aacgcgatgg ttccctggga
      541 caccacgtag ttgaggggga agaccgccgg gccgtccggc gtgttcagcg cgaggcggcc
      601 cactccgtgt gccgagagca gggcccggca ctccttctcg tcgaggtcgc gcagtgtcgg
      661 attgcgaaga gccgctccct gccccggtgg acggtcggca ccgcctccct gcagctcggc
      721 gtaggtcgtg cccagggcat cagccagtcg cacgaggctg ccgaatcccg gatccgcggt
      781 gtgggtctcc aggtaagcga gatactgcgg cgccatccgg gcccgccggg ccacctgctc
      841 caggctcagt cccctgcgcc ggcgcgccgc ggccagccgt cgaccgaggt cgccggcgcc
      901 ggcggcgatc agggaggagt ccaccccttc gccgcgggac acgcccgaag gcgccccctg
      961 cgacgcctcc gcctcttctg ccccgtggtt cacacgcgcg tcggggccgg ggaacacgag
     1021 cgtgacatcc ccggtgtcgg accagcgcac gtcgtacggc ggagttccgt cgtcgtggtg
     1081 gaggccgacg atctccccgt cccgccgcgt gacgccggtg gacggacttt cgacgatcag
     1141 ccggtcgccg agatgtgcgt acatgaccgc gccctctccg tcgaaggagt tcctcactcc
     1201 agcctcgcgc ggggacaccg cgcccaccag gcggccgacg gtccccgcgg gcctgccgaa
     1261 cggccctcat cctcggcacg aacgccccaa gtcagggcgg ctccgagcgg cacgttgaga
     1321 gtgaggaagt gcggactgcg gtggcatcgg tgctccacgg cggctcaccg ccgagaggag
     1381 gctcgtcatg cggcaccgga ctgtaggtga tctcatgacc cggcccgtcg tcgacgtccg
     1441 aacggacgca tccctctagg cggtcgccga ggcattgacc cataacgacg tcaccgccgt
     1501 cctggtggtg gacggcgtcg gccgcctcat cggcgtcgtg tcggaggcgg atctcgtccg
     1561 caaggtcgct cggcccggat cctgccgaac cggtccggct gctccagccg acggaccgct
     1621 ccgccggtga gcacgtcacg gtcgatgagc tgatgacggc acccgcagtg tgcgtgaccg
     1681 gagtggagca tcgtggaggc tgcgcgcctc atggtcaccg aggaagtcaa gtgtctcacc
     1741 gtggtcgacg aggcggaccg ctgggtcggc gtcgtcagcc gcggcgacct ccttcgggtg
     1801 tccctgcgcc gggacgacgc actgcgggag gagacatccc gtgccgtgct gatccggact
     1861 cggggtccgg cgcccaccgg catgacggtg gacgtggacg aaggccgggt gaccgtcggg
     1921 ggccgcgtgg acaatgggca gccgcttccc gtcatcgaac ggctgtgcct gggcgtcgac
     1981 ggcgtcgcct cggtcgatct gcacgtgacc ggccgggaag accgcacgcg cccggtcgac
     2041 actctcggcc gagcccgccc gaccacgctt cacgtggacg tgccatgagc gggaatccga
     2101 cggtccacac cggagaggcc gcaacccgct ccgcatcccg gttgtcggac ccgccgaggg
     2161 tcggggccgg tcgacccatc cggattcccc gtgcgtgccc gaacggcccc tggtcggcag
     2221 accaccgctg agtgaggctg aaatcgacag ccggaggtgg tcacgatgcg cgcaggcaca
     2281 accattcggc ggtccctgtg gcgttggcgc cgcaatccgc tgcgtcgccg cgaggacgta
     2341 ctcgaggcct ggatcctcct gatcgtctgg ctcgtcgtcg ccctcgcggg tcccgtggcc
     2401 ggagtgctgg cggcacacgc ctcggcacac ggcgccgcac aacgacgcgc ggagcggcac
     2461 tccgcaaccg ccaccctcgt gtcggacgtg tccggcagtc ctctgtccac ggggacggct
     2521 ggaggccgga tcgaggccac cgtgcggtgg acggcacctg acggcacccg gcactcgggc
     2581 aagattcccg tcgacgaggc aatgaaggcg ggctcgcggg tcacggtctg gacggatcac
     2641 cggaaccaac tgacgacagc gccgcccacc accgcccagg caggggtgga cgcggcgttc
     2701 atgggtgccg cgtcctcctt cgccgtcgtc accgcggcgg ccgccggcta ctacggcgcg
     2761 cgagtcgtcc tcaaccggcg tcgtcgcgcc gcgtgggagc acgagtggca ggacatcggt
     2821 tcccagtggg gacgcgcggc cagttgatcc gggacacgtc gtagggcttc caccggcgcg
     2881 acatggaacg gttctcgggt ggtgaggaag cccgtgaggg gggaggagga gcgatgagcg
     2941 acttcatggt cgtggcgcgg acggttccgc gccgggtctc caagccgtcg tacgggcggc
     3001 gcgtgaggca gaagtccgca acatgacgct tcgggtcgtc cacgcgctgg cccggcccgc
     3061 gcccgcaccg aggccccggg taccgttgtc gcggggctgg tctttcccgg agaaccgctt
     3121 ccgatgctgg tggcgcaggc tctgtccgcc gctgcggtcg tggtgggtca caggggtccc
     3181 catcccttcc agggagctct gatcggatcc ctcgcgaccg ggctcgccgc ccactccgag
     3241 tgccccgtgg tggtcgtagg cgagcccgag aatccggcgg gtcctgtggc cttgggagtc
     3301 gacggatcgg ccgccggagc ggctgccgtc cgccttccgg gagacttccg tgcagggtgc
     3361 ggacatcacc gccgtgcacg cctggacggc ctggaacgcg ccgatgccgc ctcccccaga
     3421 cgagagaccg agccctacgc ctgtgaaccc ggcatgctcg ccgcggagga agggcggctg
     3481 ctggccgaga cgctcgcggg catgtgcgcc cgctatcccg aggtgagggt ggaacgcagc
     3541 accgtccacg gagtgcacgg ccgacgttga tcgaggaagg gggcacgatc acgacggaag
     3601 tcgctcaagg ctttcctgcc ggcccagcgt ccggcgaccc ggcccggcgg actcgacgcc
     3661 caccgggccg gccgtgtcac acagcgtttg cggcgacgac ttcgcgcttc gggccgccga
     3721 ggaccacctt gagcgctccg gtgtcggctg ccgcggagaa gacctcgtac gcctcctcca
     3781 tgcgctccag cgggaacgtg tgggtcacca actggccggt ggggagtcgg ccggacgccg
     3841 ccatgcgcaa cagcgtcggc gtggaacggg tgtcgaccag accggtggtg acggtgacgt
     3901 tcttgctcca caggtcttcc aggtgcaggg tcgccggcct gccgtgcacg ccgacgttgg
     3961 cgacgtgccc gcccgggcgc accacgcgcg tgcacatctc gaacgtctcg gggacgccca
     4021 cggcctcgat gaccacatcg gcgccgaggc ccccggtgag gtcggcgacc agttgctccg
     4081 ggtcctcgcg ggcgtccgcc acggcctcgg ccccgagctt ccgggcggcc tccagccgag
     4141 cggtggccag atccacgacg acgatccgtt cgggtgcgaa cagccgtgcc gtggcgaccg
     4201 cggcgagtcc tatggggccg gcgcccacca cgacgaccgt gtctccgggg ctgacgcgtc
     4261 cgttgagcac gcccacctcg taggccgtcg ggaagatgtc ggcgagcagc acggcgtcct
     4321 cgtcggtcac cgcgcccggc agggagtgca cggagaggtc cgcgtacggg actcgcacgt
     4381 actcggcctg agtgccgttg atcaggtggc cgaggatcca gccccctccg ccgaggcact
     4441 ggccgtacac gccctcacgg cagtaacggc accttccgca ggcggtgatg caggacacca
     4501 ggacgcggtc tcccggccgc acggtgcgta cgtccgtgcc cacctcgacg atctcgccga
     4561 ccgcctcgtg gccgaggacg gttccgggcc gcacctcggg gacgtccccc ttcaggatgt
     4621 gcaggtccgt cccgcagatg gtgacggcgt cgacccgcac gatggcgtcg gtgggctcct
     4681 tgagttccgg atccggtatg tcctcccacg cggaccggcc cggaccgtgg aatacgtagc
     4741 ctttcatcgt gatgctcact ctccttgtgc tcgggagcat ccggggccac ggtgaccgga
     4801 ccgcgccggg cgggcccacg accgtcggta cgacggggat tgccccacac ctccagactg
     4861 tccccggcag cacgaacccg cttgggccgg tcggcccccc gcccgccgcc tgccggcccc
     4921 gggtctgttc ggtgtgctca cgtccgctcc ggcacgacga cgaccgggca ggccgagcgg
     4981 tgcaggacgg cgtgggcgac ccggccgagc cgcccttggg tgcggcggcc gatcaccagc
     5041 aggccggctt ccgccgaagc ggcgggcagc accgcgcgtg ccgggccctc gacggtgtac
     5101 cgacgcacgg cgacgtcggg cggtgcgtct tccagggctg cttccagttc cctggctgcc
     5161 cgctcctcgt accgccgggc cggttctccc gccggcaagg ggtgatcgat cgtctcgtgg
     5221 gcgggacagc gccaggcccg aacggccgca acgggcacct gacgcagacg tgcttccatg
     5281 aaggcgagcc gtaggaccga cgccgatacc tcgccgacac cgacgacgat gcggccgttc
     5341 cgtcctccga tggcgcggtt gtcgtggttg ccgcgcagca cgacgaccgg gcagtcgctc
     5401 ccggcggcca cggtccggct gacggaaccc agcagtctgt cggcgatgcc gctgcggcct
     5461 cggctgccca tgacgatcat ggatgcgttg cgccccgcgc agatcagggc gtgctcggcc
     5521 tcgtcgggca ccgtctcggt ggtgacgacg aggtcgggat gccgacgccc ggcacggatg
     5581 gcggcggccg cgaggatgtc gtcggcctgc atgtcggtgg agggcttccc cggctcacgg
     5641 gcgagcgcgg cgccctcgta ccgctcccac aggtccccga agaccaccca gagggggact
     5701 gcgtgcaggg cggcctcgtc ggccgcccag tcgacggctc gcaggctggg ctcggagccg
     5761 tcgaccccga ccactagagg cagatacatg acgcccctcc tctcgaccgg gatgcgtcag
     5821 ggatgggcca cgacggcgac gggggcactg acacggtgca gcaccgcgtg ggcgaccgca
     5881 ccgatgtgca cgccgagcgg gctgggccgg atgcgccgtc cgacgaccac cagggacgcc
     5941 tcgtgcgacg cttcggccag aaggtcggcg gggctgccgg ggcgggatgc ctcgacgacc
     6001 tcgacatccg ggtacgactg ccgccagggc aggagcagcc gggtgaggtc ggcggccttc
     6061 ctgcgggcca ccccttggtc cggtacgccg ccggcggtca gcgagggata gtacggcggt
     6121 ggccgccatc cgctgaccac gtgcacggcc gtgccgcggc gctgtgcctc gtcgaaggcg
     6181 aacgagagca cgccgtcgtc ggggctgccg atgtcgagtc cgacgacgac cggccggcgg
     6241 cggttggccg cgggcggcac accgacggaa tccacgacgt gttcgccggc cgcctgctca
     6301 ccggcacgta cgaggaccac gggagtctcg ctgtgggcga tcacggactg tccgacggaa
     6361 ccggccagga agccgccgag tccgctgggc gcgcgcgagc cgaggaccag cagttccgcc
     6421 ccgtcggcgt ccctgaccag ggtgtccgcc ggtgggccgg accgctggtc actggtcacc
     6481 acgacaccgg ggtggcgcag ccgcagccct tcgcccacct tctgcgggac acgctcggtc
     6541 cagtgctggt gtgtcttcgc gccgaggatc gaatcctggg ccaggaccgc gggagccggc
     6601 tcccacacgt ggagcagacg taccggcagg tcgcgcagct cggcctcgcg ggccgcccac
     6661 tcggcggcgg cgtggctctc gggcgagccg tcgattccca ccgtgatcgt gcgggtcatg
     6721 tcgcgcacct cccgtgtcgg cccttccgac tccagcgtgt cgcgcaactg agccccgggg
     6781 tagggccact cgtcctcgga cacggccgag ggtcccttcg gcgggcccgt gcggcgaacc
     6841 gcgggtcggc atgccggaag caccgtccgc cgggtgccct gcgggtgttc agtgcccctc
     6901 gcccttcagc cggtcctccg cgtgggcggc gacgacggag gcggccggca cgaggtccga
     6961 gccctcgatc ggcttcagga cctgggtgag gtccggcatg ctcgaccgcg gctcccgcca
     7021 cgcggtcacc ccgtcccata agccgtacgt cccgcaggtc acgccctcgc gtcgggcacc
     7081 ggcttcgagg acaccgaccg ccgcgcggca cacgtcttcg cccagcaggc gtacgaggca
     7141 ggcgtgcgga ggatcgtcta cctgggtggt ctgactccgc ggggcgttcc cgagcgcacg
     7201 ctctcccctc acctgcgctc ccgcgcggag gtcggcccca tcttggtccg cgacgtgttg
     7261 cactacctgg ccggggcggc caccatgccg gacgacatcg accgggcctt cgacgtcggc
     7321 gggccggacg tgcccaccta ccgcgagatg atgcgccgcc acgccaccgt gagcggactc
     7381 cggcggcgga tcatcgtgcc cgctccggtg ctcacccccg ggttgtccag ccactgggtc
     7441 ggcctcgtca cgccggtccc ggcctccatc gcccggccgc tgacggagtc tctgcgtcat
     7501 gaggtcgtgt gccaggagca cgacatcgcc cgctacgtcc ccgacgctcc cggccggccc
     7561 ctgccgttcg acgtggccct gacgctggcc ctgcggcggg tccgggaggc ccaggtcgcc
     7621 actcgctggt cgtccgcctc cgtgccggga gcccccagcg atcccctgcc caccgacccc
     7681 gactgggccg gcggcagcct ctacgaggac gagcggcacc tgccggtcga cgcgtccccg
     7741 gaggcgctgt ggaaggtggt ggagggcatc ggcggggaca acggctggta ctccttcccg
     7801 ccggcctggg ccgtccgcgg ctggctggac cggttcgtcg gcggtgtggg tctgcgccgc
     7861 ggccggcgtg acgcccagcg cctgcacccg gcacgaccgg tggcgtggcg aggaggacgc
     7921 cgccgaggac atcgccgcct ggcgggacgg acgggctatc cggtcgtcga cgcggccatg
     7981 cgccagttgc gccaccaggg ttggatgcac aaccgggcac ggctgctggt ggcgagcttc
     8041 ctgaccaaga cgctgtacgt cgactggcgc atcggcgccc ggcacttcct ggacctcctc
     8101 gtggacggcg acgtcgtcaa caaccagctc aactggcagt gggccgccgg caccggcacc
     8161 gacacccgcc cccaccgcgt cctcaacccg ctcgtccagg ccaggcggtt cgacccggac
     8221 ggcgtctacg tacggcgctg ggtccccgag ctcaggagcg tggagggcgg gaaggtgcac
     8281 gaaccctggc gcctggcggc ggcggaacgc ggtgaactcg actacccgga cccgctcgtc
     8341 gagctcgccg acgggctcgc gcggttcaag cacgcccgcg gccgggactg aggggacgcg
     8401 tcgtgcattg gctcttcggc gaccagctcg gcccccactt cctcacgccg ggcgaagagg
     8461 ggcccgggcc ggaaactccg ctgctcatga tcgaggcgcg ctccgtcttc cggcggcggc
     8521 gtttccaccg ggccaaggcc cacctggtgc tgtccgccat gcgccaccgc gcggccgaac
     8581 cgggcgaccg cgtcacgtac gtacgcgccg acacctaccg tcagggactg gcccggaccg
     8641 cgcgcgggcg cccggtcggc gtccaccacc ccacctcgca cgcggctctg cgcctggtgc
     8701 gcgccctgcc ccaggtgaca gtggggcccg cccgcggctt cctcgtgccg atgaccggct
     8761 tcgccgcctg ggccgagggt cacggcggca agcgcctgcg gcaggaggac ttctaccgct
     8821 gggtccgccg cgggcacggc ctgctcatgg acggcgagca gcccgcggcg ggacggtgga
     8881 acctcgatca cgacaaccgg gaacccccgc cccgcgaggc cgcctccctc caggtcggcc
     8941 gcccgtaccg gccccgcgag gacgacatcg acgaagaggt ccgccacgac ctcgaccgct
     9001 gggaacgcga cggggacgtt tccttcgtcg gacgggacgg tccccgcctg ttccccgcca
     9061 cccggacgga ggggctgcgg gcactgcgac gctttgtcga acaccggctc gccaccttcg
     9121 gaccgcacga ggacgccatg ctcgccgccg accccgtcat gagccacagc ctcctttcgt
     9181 ccaccctgaa cctcggcccg ctcgacccgg tcgagtgcgt cgaacgggct gagcgggctt
     9241 ggcgcgaggg ccgggcgccg ctgaacagcg tggagggctt cgtgcggcag atcgccggct
     9301 ggcgcgagta cgtctggcag ctgtactggt acttcggcga gggctaccga cgctccaacg
     9361 cgctcgggca caccgccccg ctgccggact ggtggaaccg gctggacgcg gacgcggtcc
     9421 gggcgaactg cctgcgcacc gtcctggccc aggtccggga cacgggctgg acgcaccaca
     9481 tcccccggct gatggtgctc ggcagtcacg cgctccagcg gggctgggac cccgccgccg
     9541 tcacgaactg gttccaccgc tgcttcgtgg acggctacga ctgggtcatg ctccccaacg
     9601 tcgtcggcat gtcccagtac gccgacggcg gccggatgac caccaagccc tacacctcgg
     9661 cgggtgcgta cgtgaaccgc atgagcgacc tctgcggccc gtgcggctac cggcccggcg
     9721 accgcacctg cgagcacgcg tgtccgtaca ccaccgggta ctgggcgttc ctcgaccggc
     9781 accgggagct gctggccggc aatcagcgcg tcgcccggcc ggtacggcag tcggaccggc
     9841 tcgccgacct cccggacgtg tgcgcacagg gcacgcgcgg ggtgacgcac cgccatgagc
     9901 ccccgccgtt gcgccgacgg ggtgaagtcg gaccgcaccc cgtgccggaa cgggcagaag
     9961 tcagtgcatc cacaacaggg cacccggcgg aagcagtggc gtgcggacaa ccgagagtga
    10021 gaaggggctg cgcatgcctg gactgccgcc gatggtggcc ccgccggccg aacaggtcga
    10081 cgaccccgtc accgcgaccg atgcggcgaa cgcggtcgac gccgtcctcc ggggggtact
    10141 ggacgaacgg ctgcgccact gccgtgccgt cgaccccctc ttcgcccggg aactggccga
    10201 ccgtctcgcg gcgctgaccg cccggggcgg caagcggctg cgcaccgcgt tcgcccactg
    10261 cggctggcgc gccgcgggcg gctcgggaga cgccaccgcc gtcctgcgaa cgggagccgc
    10321 gctcgaactg ctccaggcgt gcgctctggt ccacgacgac gtgatggacg gctccgtgca
    10381 gcgacgaggc gcaccggccc tgcacgtcga cctggcccgc gggcactggg cagcgggtat
    10441 gcacggctcg tcggagtcct tcggcacctc ggccgccgtc ctcaccggtg acctggcgct
    10501 cgcctgggcg gacgacctgc tgaccgagac ggcactcggt acgccgcacg gcccgcgcct
    10561 gcacggggag tggcgggcga tgcgcaccga gatggtcgcc ggccagtacc gcgacctgca
    10621 cgcgcaggcg gcacggtcct ccggcgtcga cgaggcgctg gccatcgcca ccttgaagag
    10681 cgccctgtac accgtcgcgc ggcccctcgc gctgggagcg gtactggccg gagcggccga
    10741 cggggacgca ctggaggcgc tgcgggcggc cggccggtgc gccgggctgg ccttccagtt
    10801 gcgtgacgac ctcctgggcg ccttcggcga ccccgcgctg accgggaagc cggccgacga
    10861 cgacctgcgc tcccgcaagc tcacctacct gctcgccgtc gccgtccggc tcgccgatgc
    10921 cgccgatgat cacctggcgg ccgcggcgct ggctccggac gcggacccga agtccgagaa
    10981 ggccgtgcgg caggtgcggt ccgcgctggt gcgcaccggc gcccgggacc tggtggagac
    11041 gaagatcggg gagctgacgg acatgagcct cgcgcacttc gaccgctgcg gagcgcgccc
    11101 ggccgtgcgg cacgagttcg ccgcactgat cgggcgcgcg acgggcgcgg tcccgcgtgg
    11161 caccggggag gtcgtgtgag gagggtgccg gggccgaccg gccacgtcgt cgtggtcggg
    11221 gccgggctgt ccgggctggc ctgcgccctg cacctgctgg gggccggccg ccgggtcacc
    11281 gtcgtcgaac gggacgccgg tccgggcggc cggtccggcc gggtacggct gggcggttac
    11341 gagctggaca ccggtcccac ggtgctgacc atgccgcacc tggcggacga ggcgttcgcc
    11401 gccgtcgggg acagcctccg ccgccgcgtc gaactgaccg cgctggaccc ggcctaccgg
    11461 gcctgtttcg cggacggttc cgcactcgac gtgcacaccg acggcgaggc gatggaggcg
    11521 gaggtgcgcc gcttcgccgg accggcgcag gcggccggat accgcgatct gcggcggtgg
    11581 ctcgaacggc tgtaccgggc gcagatgcgc cgcttcatcg acacgaactt cgactccccc
    11641 ctccaactgc tgcacccgga cctggcccgg ctggcggcac tggggggatt cggacggctg
    11701 gacggccgca tcggacgctt cctgtccgac gagcggctgc gccgcgtctt ctccttccag
    11761 gcgctgtacg ccggtgtggc cccggcccgc gccctcgccg cctacgcggt gatcgcgtac
    11821 atggacaccg tggccggcgt ctggttcccc aagggcggca tgcacgcgct cccccgcgcc
    11881 atggccgacg cggcggcaac cgccggtgcc gatctgcgct ggtcggccga agtgaaggcg
    11941 ctggagcggt ccgcaggacg ggtacgcgcc gttcacctgg cctccggaga gcgcatcgcc
    12001 tgcgacgccg tggtgctgac gtgcgagctg tccaccgcct acgggctgct gggacgggcc
    12061 ccccggcggc cggcccggct gcggcactct ccgtccgccg tgatcctgca cgcgggcacc
    12121 gaccgcacct ggccgcacct cgcccaccac accctctcct tcggcgccgc gtgggagcgc
    12181 accttcgagg aactgacccg tacgggagaa ctgatgagtg acccctcctt gctgatcacc
    12241 cgccctacca cgcacgatcc cgccctggca ccgccggggc gccacctcca ctacgtcctc
    12301 gcgccctgtc ccaacacgga cgtcggtccg gatgccgtcg cgtggcgtga cctcggcccg
    12361 cgctaccgcg agagcctggt cggcgtactg gagagccggg ggctggaggg gttcgcggac
    12421 agtgtccagg aggagctcct ggtgacgccg ctcgactggg acgcgcaggg ccatgcggcg
    12481 ggcagcccct tctcggtctc ccacaccttc gcccagaccg gaccgttccg cccgcgcaac
    12541 ctcgtacggg ggctggacaa cgtggtgctc gcgggctgcg ggaccacccc gggtgtcggc
    12601 gttccgaccg tactggtcag cggcaaactc gccgccgcgc gggtcaccgg cggtgccggg
    12661 tcccggcccg cccgcacgcg tcggtccccg gccgtttccg acccgtgccc cgccccggtc
    12721 ccggcaggtg ccgatgaccc gtcgtgaact ggacgccgcc gggatcaccg atcccctgct
    12781 gcgcgccgcc tacacccggt gccgccgtct caacgcccgc cacggcaaga cctacttcct
    12841 ggccacccgt ctgctgccgc tcgaacggcg ctcggccgtg cacgccctgt acggcttcgc
    12901 ccgctgggcg gacgacatcg tggacgacct cgaccggcac cgcacggccg gggaacgcga
    12961 ccgtgcgctg cgccgcctgg agagcgacct ggccgacggg ctgcgcaccg gaacgggccg
    13021 ggaaccggtg gtccgggccg tcgcggacac cgccgaccgg tacgacatcg accacgtgct
    13081 cttcgccgac ttcctgtcct cgatgcgtgc ggacctgacc gtcacccatt accccaccta
    13141 cgccgatctg caggcgtacg tacacggttc ggcggcggtc atcggcctgc agatgctgcc
    13201 cgtcctcggc acggtcacgg accggaagga ggcggcaccg cacgcggcgg cgctgggcgt
    13261 ggcgttccag ctcaccaact tcctgcggga cgtcggcgag gatctcgacc gcggccgtgt
    13321 ctacctgccc ggcagcctgc tggccgcgca cggggtggac cggcccctgc tggagtggag
    13381 caggcgcacc gggcgccgcg accgccgcat ccgggccgct ctcgtcgcgg cggaggccat
    13441 gacgcggcgc gtgtaccgga cggcggagcc gggcatcgcc atgctcgatc cacgggtgcg
    13501 tccctgcatc cgtgccgcgt tcaccctcta cggcgggatt ctcgacgcga tcgccgagca
    13561 ggactacacc gtgctgcatc gtcgcgcggt ggtgtcgcgc cggcgtcggg cggcaacggc
    13621 cgccgagggt gtgctgtgcg tggccgctgc ccggtggcgt gcccgcacct cgccccgggt
    13681 ggaggcggcg ggtggtccgg cagccgagtg gcagggaccg gtgcggtgag tggtcgacgg
    13741 ggcggcaggc ggtggtcgcc acccgtgcgc cgacgtggtg cgggccccga ctgggcggct
    13801 cagactccga cctggcggca ggcgcggccc tcgctcatcg ccgacgcgct cgagcgggcc
    13861 tccgcccggc cctccggcaa ctggttcgtg gtcggcgcct cccggcaggt gcgcgcgggc
    13921 gaccggccgt acggccggac ggtcggtggg gtggaggtcg tgctgtggcg ctcggacgac
    13981 ggcgagcccc gtgccggctc cggcatctgc ccgcacctgg gcgctccgct gcgcgacagc
    14041 cgggtggtgt gcggcacgct ggtctgccac tggcacgggc tcgccctgga cggttcggcg
    14101 tccgccggct ggcggccgtt cccggtgcac gacgacggtg tcctcgtctg ggtaaggctg
    14161 gacgaggtgg gaggcgagga gcccaccgag cggcccgtcg tgcccacgcg gcccgcgacc
    14221 ggccgggggg tcgactccgt gttcacggcg acggggcggt gcgaaccgca ggacgtggtg
    14281 gccaaccggc tcgatccgtg gcacggctcg tggttccacc cgtactcgtt cgtggacctc
    14341 tcggtcgtgc gggagccgca ggggggcgag gacgacgctt tcgtcgtcga cgtctccttc
    14401 cgggtggccg ggcggctcgt ggtcccggtg cgggccgagt tcaccgcgcc ggagccacgc
    14461 acggtcgtca tgcgcatcac cgacggcgag ggcgccacgt ccgtggtcga gacgcacgcg
    14521 acgccgctga ccgggccgga ccacgagcgt ccccgcaccg ccgtggtcga ggcggtcgtc
    14581 gccgcgtcgg accggcccgg tttcgccctg gcacgggccg ccgcccccgt actgcgcccg
    14641 ttgatgcgcc gtacggccgg gcggctgtgg cgcgacgacc tggcctacgc cgaacggcgc
    14701 tgggcactgc gcagcaccgg ccggtttccc ggctgaggac gcgggcgccg gtcagggagc
    14761 cgagcggtgc cccgcgacgg ctccgaacgc tcggagcacg ggtgaacgac ccgtccgggg
    14821 gaccgtccac aggacctgac cacgcactcc ccggtcggcg agcagggcgt tcgcggccag
    14881 gaagccggtg gtggcggctc gttccatgag ggcgacgggc aggtcgcagc ggattccgtc
    14941 gccggccagg gtcagccagg gatgcggggt acgcacggtg gggcgccgcc ggtgggaacc
    15001 gacctcgaac atcgggcagt ccgcgcgcca ttcgtgccgg gcgtcgacga cgcgggcctc
    15061 gcgggtctcc gggtacgcct ggtgcagccg gtcgacgagc tcgtcctgca cctccttcgg
    15121 ttcggccgcc gggtccacgg cgtaggcgtg cagttccacg acggatcccc cggtccgcgc
    15181 ggcccagcgg gcggcctcgc cctcgtaccg ctccaggacg ctgacgttgt ccagtccgcc
    15241 gtagccgctg gtgccgagga acccgggccg gtcggcgtcg accggccggt cgagccagag
    15301 ccgcgagacg aggaacggcg gcgcggtgcg cagggcggcg atgccgtctc gccaggtgtc
    15361 ggtgcccagg ccgggtgacg cggcgacggt ctgccgcagc cccgcggtgt cgagggccag
    15421 caccaccgcc tggtgacggt cggcaccggt gtccgtgagc acgtccgctc ccccgtcggc
    15481 gcggggaagg atcccgtgca ccggggtgcc ggtgcgcacg tcggctccga ggcgccggag
    15541 gtagtcgccc agtgggttcc acagtgcctg ggggaagggt tcgaccggca cgtcgaagag
    15601 caggccctcg gacgatccga ggaagtagat gtggaacatc agcagcagtt ccgcggcgga
    15661 cagccggcgc ggatcggcga agaagctgcg ggagaacacc tcgaaggcca ggtggtgcgc
    15721 cgcttcgggg aagcgcacgc tctccaggaa cgcggtggcg gtgacgccgt cgaagcgttc
    15781 gtacacctgg ggcacgcgca cgtcgaggag cggcagggcg gcccgcgggt ccatcgcggc
    15841 gaggtcgcgc catccgaagg tggggctgag ggcgacgaat ccgatcgcgc tgaggggcgg
    15901 ggtccgcggg acgcgggcga agccgtcggt caggccaccg ctgtgccgca aggggtagtc
    15961 gggcagcggg gtgaggcggt ccaggccggg gtcggtacgg cggagcagtc cgcggaggtt
    16021 gtagtactgg cggaagaagg cgtggaaccc gcgggtcatg gtcacggcgc tgccgtcggc
    16081 cagggtggtg cgccggccgg agagcctgcc gccgaccgcg tcctccttct cgtacagcgt
    16141 cacgcgggcg ccgcgttcgg ccatgagggt ggccgcggcc agaccggcga tcccgccgcc
    16201 gatcaccgcg acggacggct cgtcaccgcg tccgaatcgg tccgcaccgg gcgcggggaa
    16261 gacgatctcg gccttgcggt cgcggccccg tcgggcggcg gcggtgcggc ggacggtcac
    16321 aggacgcgct cctctgtcgt ggtggggccg ccgttgcggg cgaggaaggt gtgcacgatg
    16381 cccgtctgcc atccggcgac gggggcgacg cgcaccgagg tcaggccggc ccgcgtcagc
    16441 cgggcggcga attcgggggc ggtgtcgaag gcgacgacgc tgcgccggag gtggcggtag
    16501 agggtgcggt cgccggtgag ggtgcccgcg gggatgacga ctccgcggca caccgccgac
    16561 cacagggccc ggtgccccgg cgagccgctc aggctgtact cgtgggcggc gaagcgtccg
    16621 cccggcctca ggagttgccg gacggcccgc aggaccgcgt ccgggtcggt gacgttgcgg
    16681 aacaggtagg cggcgaagac ggcgtcgaag gggccttcgt cctcacgggt cgtggcgaac
    16741 tcctcggcgg tcaggtggag gaagcgcacg cgggcgggcc acggtttgac cagtgctcgg
    16801 cgcagcatgc ccgcggaggc gtccacggcc gtgatccggg ctcgtggcgc ggccctgagg
    16861 agggcccggg tggaggcgcc ggtaccgcac ccgaggtcga gcagatgcag tccggctccg
    16921 tcggcgggga gcgcgagacg gcgggcggaa cgcaggaggc ccgtgcggta gccggggttc
    16981 agggccgtga ggccgtcgta ggtgtgggaa gcgtggtcga aggcgcgggc caggtcgtgg
    17041 tcgcgcagga gtgtcatcgg ttgttccctc cggttcgggc gaggggctgg gaccggcgtg
    17101 gcaggaaggg cacttcggcc gcggtgcgca gcatcggccg gacgggagtg cgcaacccga
    17161 tgccccactc ctcccggagg gaggtcgtgc cgtcgaggaa cctcagcagg cgctcggccg
    17221 ggacccggcg gaacaggtcg gtgaagaagc gcggcccgtc gatgcgaccg gtgtccagcg
    17281 cacgcagcag gaccgcgtcc atggcccgcg cccgtcgccc gtgcggtgcc gggacgcggt
    17341 cgtggccgtc ccgcagggcg gcggcgatgg ctccgctgtg ccgttgcacc gcggcgaacg
    17401 tgtagccggt ggcggggcga gtggcaccgc ccgcggtccc gatgcggtac acggccggcc
    17461 cggcacgtcc cgggaagcgg gcgtcggtca tggggatgac gccttgttcc gtccgttcca
    17521 cggtgagttc gcccagtccg aggatgtcgc ggcagtagtg cccgagtgcg gactcgtacg
    17581 cctcggtggt cagcggggcg cgggagaact cggtgtactc cacgagcgcc cggtccggcg
    17641 ccagcggcag gacgtagccg aaggcgagtc cgtgggccgg ctggggcacg cggaagtcca
    17701 tcaggtccgc gaccgccggg tcgaaccggt cggtgcgggt gtgtacgaac cagccgcgga
    17761 agtgctgcag cagacacgta cgcgccggcg gcagctcggg aagcggccgt gagtcgaaga
    17821 cccgccgggc gtacagcgtc agcggccggc ctccgggcag cgtgcaccgg acctccgtgc
    17881 ccgcgggcac ggcgcgaacc gattccgccg taccccgcag aaggcgcgca ccgtccgtgc
    17941 gggccaggcg gccgtggacc atccgctcga agtcggcgga acgcaccatg cggtaggtga
    18001 acggggccgg atcgacggtg accgacccgc cgtcggcgcc gtgcagacgc agcacggacc
    18061 aggacgcgcc gaccgcctct tcgaggccgt cggcggccgc cccccagtag caccaggtgc
    18121 gctccgcggg gcgcagcggg ccgtccggcg gctcgaccag ggtcatggca ggggccgtgc
    18181 cgttctccgt cagccggtgg gcgaggctga gtccggccgc accgccaccg atgacgagca
    18241 cgtcggagtc ctgggcggaa cggggtgtca ccacagtcgc cgttcgacga ccgggcttcc
    18301 gtcgggaccc ggatgcggcg gctcggcggg cgtcggacgg tcggcgtcca tcagtacccc
    18361 accaccccgt caccggcctt cgcggccgcg ccgcaggccc gggcggcgcc tgccaccggg
    18421 tcacgcacac tcttcggttc cacgcttcac ccctcgtacg gacggcgggt ccgtccggtc
    18481 gccatggctt cgggaccgag gccgtccgtg gatgcggccg ggcacgactt cgtcatcggc
    18541 ctcacctctg cggttcccgg tcggcccgta cctcccgcgc cgcgcgcgta cccgaggcca
    18601 gcgcgccctg tacggagccg gtcgcccggt ggtctccgca cacgtaccgg ccggggccga
    18661 tgcgggtggt gcggctcagc ggccaggggg gaagcatcgc cggcagtgcg ccgtcgaccg
    18721 tgcgggccgc gacctgctcc cagccgctcg tgtcggtgcc gtacagctcg gccagccgcc
    18781 ggagcaccgc ctgtgccctg ccgggcgggt ccgtgcccag tacggaagtg gagaccagcc
    18841 cggtgccggg gggcgcgtac gtgggagcga cctggctgag gacgcacgtg ttcaggatgg
    18901 ctccggtgct gtccaccatg aggatcggtt cggccgtcgg cgggctgtcg gtggcgtggt
    18961 agtaggtggt gacggtgcgg gtgtccggga cggtcaggtc cgggagcagc ccggcggcgg
    19021 tcgccgggtc cgtcgccacc acgacgaccc gggccggcac ctcgccgccg tccccgagca
    19081 gcactccggc gtccgtgatc tccgcgacgg gcgtgcccag gcgcaggacg ccgtcgggca
    19141 ggccgtcggc cagctgggcc ggtacggcgc cgatgccctc cgccggcagg cacagggatc
    19201 ctcggaccat gctccgccag accaggtgga agaaccgggc tgaggtctcc agccggtcct
    19261 ccaggaagac gccggacagg aacggccgta ggatgccggc gatcgccgcg tccgacagtc
    19321 ccacccggga cagggccgcc gaagtgggac ggtcccggcg ccgtcgggtg acggccacgg
    19381 gcagaacggc gtcccgtgcg gtgagtgccg ccagcgcggc cagatcgcgg gccggcagag
    19441 cccgccccgg cagcagcgtc cccgccgcgc ggggctccct ggtcggatcg gcgaggcgga
    19501 cgggcccgtt cgacgtgtgg gcgacgacac ccgccgtgaa cggcctcagt cgcagactct
    19561 tcagctccat gcgccgcttc acctgcggat aggaggtgtt gaacacctgg aacccgcggt
    19621 ccagcaggaa tccgtcccgc cggtccgtgc gcatccggcc gccgacaccg tcggaggcct
    19681 ccagcagtgc cacccgccat ccggcgcggc acaggtcgag ggcgcacgcc aggccggcca
    19741 gacccgcgcc gacgacgacc gcgtccgctg cccggtgttg tccgtcgctc atatgtctcc
    19801 tcactcgacg tcacgtccgt gatgcccagg ggcaaaggcc ggccggtcgg cctctccgcc
    19861 ccggccggtg ccccggaccg gtcggcacgg tcggggccgg aagccggtgc gagtgcgggg
    19921 aaacgcccgc cggccgacga ccgggccacg accaccgggt cagcggacca cgtcccccgg
    19981 cccatgccca ggcgccacga ccaaggacgg ccggacgaca acacctcacg ggtacaccga
    20041 cggctccaga gcggcgaccg cctcggcaag ccccgacgga cgcgccagac cggccaccgc
    20101 ctggcccgcc catccagggc ccagggtcag gacgacgggc cggcgccggg ccccgcgcac
    20161 tccccactcc atggcggcca cgtgctgggc cagcggccgg ctggcggtgg tgcgggactg
    20221 cgaccacagc cccaccgcgg cgggcccggt cctgcgcacc gccgcgacga gcgactcaac
    20281 gggcagcgca ccgccgaaca tccgcaccgg gacgcctcgc tccgtgagtg cagcggacag
    20341 tacctccaac ggcagagtgt ggttctcccc cggtacgcag gcgagcaccg tggtggaacc
    20401 gggacggtcc tcgaccgcgg ggggcgcggc gcggcggagc gccccggaca cgtgccagga
    20461 caggaagtgc tcgacctcga cgtacttctc gccggacgtc tcccacttcc ggccgactgc
    20521 ctggagcgtc ggcacgatca cctcggtcca ggccgcgacc aggccgtgtt ccgcgatcgc
    20581 ggcgagcagc agttcgtcca aggcggaggc gtccagacgc agggcggccc tcgcgatccc
    20641 ccggcactcc tgtcgtacgt cgcccagttg caggccgctg cccgcccggc tccggcgccc
    20701 ggtgggagca cgtcgagccg cgtcggtgtt tcggggcccg gccgccgtcg gacgctcttc
    20761 actgcgcgcg agccgtgccg cctcggccgg tggcagcccg gtcgccgtca gggcgcacat
    20821 ccgttccagc ctcgccaggt ccgccgccgt ccagcgccgg tgccgtccgt cgacgtgcgc
    20881 gtccggcccc agcccgtacc ggcggtccca cgtgcggacc gtggtgggcg ccacccccag
    20941 acgccgggcc acctcgccgg tggtcaatcc gccacggcgc ggaccgccgt cgtcgaccgg
    21001 ctcgtcgccg tctcccgtgt acgcgttcac atgcccacta tacgacgcac aaacgacgca
    21061 tgttgcttgc gtcgtttcct cacccaacac tgggaccacg cacacggcag ccacgcaggg
    21121 tagaccggcg acgtgccgct cggggacggc ccctcccgtc cccgtacgac gcacggcagg
    21181 aggaacgggc atgaacacgc gtacacgacc gaccaccacc ccggtcccgc ccgtggagga
    21241 gacgcggtac gaggaggagc tggcgcacgg cctcgtgaag gccgacgagg acgcgttcgc
    21301 ggccatctac cggcgctggg ggtcgctcgt gcacactctg gccacccggt ccctcggcga
    21361 cgcccacgag gcggaggacg tgactcagca ggtcttcgtc ggcgcatggc gcgggcggca
    21421 cggtttccgg cccgagcggg gcacactcgg cgcctggctc gtcggcatca cgcgccggaa
    21481 ggtcgtcgac gcgctggccg ccaggacacg gcgcctgtcg ctggtcgagt cggccgggca
    21541 ggacatcacg cccgcccgtc tcgtccagcc ggcactggac gaggtactcg accgcgtact
    21601 gctcgtggag gccctgtccc gattgccgca ggcccagcgg gatgtgctgt gcatggcctt
    21661 ctacgaggac ctgacgcagg cgcagatcgc ggaacgcacg ggggttcccc tgggcacggt
    21721 caagagccac gcccgccgcg gcctgcatcg gctgcgcacg gcggtcggcc cgggcgccgc
    21781 acatgacacg tgtgtctgac cgggccggag cagagacgcc ccggggcgca tccacggcac
    21841 cggtcgccgg cgaaacacct tcgagaccgc ccagcagacg gaaactccct acggaggggt
    21901 gattcccatg atgtcccgga ccaccatcgc cgtcgccggc tcggccgggg cctgtgccct
    21961 ggccccgacc gcacccgccg ccacggctgc tcccgagcag gcgcaggaca cgggcctggt
    22021 gtccgtcttc cacggcatcc ccggcacgac ggtcgacgtc ttcgccaacg gcgacgaacc
    22081 actcggcgac ttccagcccg gcacggtgac cgaaggcggc aacacgaccg tcgccgccca
    22141 tctctccgcc gacggcaagc cccggctgac gacgttcacc gacgacgtct cgaagacgga
    22201 cgccggcagg tcacgcctca cggtacggca cgtcgcggca gcacccgccg tggacgtacg
    22261 ggccggcgga catcctctct tcaccggcct ggcgaacccg gacgaggaca ccgcgctcgt
    22321 cgaggccggc atcgtgaacg ccgacgtcgt gctcgccggc acggagacgg tggtcgtagg
    22381 accggccgga ctcgacctca aggagggcac gaccaacgtc gtctacgcct ggggcagcgc
    22441 cgaggaccag actctggctc tgcccggcca ggccttcggc ggcatggatt cgacgcccct
    22501 cgcggtccac ccgggcgccg gcggcacggc agccaccccg aacgcgtccg accggtggcg
    22561 tgcccgggcc gcgacgccgg cacgatcgcg gtgacagccg tcctcgccgc ctcgaaccgg
    22621 ccgccggagc ccacgccgga ccgcgcgacc gtgacggccc ccgtcctcac acagtccgcg
    22681 tggagaagac gaagcccgag gcacaggagg gcgcagtggg tcacgtgcat ccgtcgcacc
    22741 tggtggagct ggcactcggt cacgccagtg gcgaggcgga cgtcggcgcc ctgcggcatg
    22801 ccgcgtcatg cccgcgctgc cgcgaggaac tgctccggtt gacccgcgtg gtgaccgctg
    22861 cgcgcggcgc ggaagcatcg gacctgccag tgcctccgcc cgagcgcgtg tggcagcgca
    22921 tcgccctcga agtactcccg gagaccgacc gggtgccccg tctccgggaa tcctccgctc
    22981 acgggtccgc cgacgagagg gttcgcggtt cccagcgccg gtggaccgac cacgcgggcg
    23041 agggcctcct cggactggct ctggccatcg ccgtccttct gctccggcgg tggcggatca
    23101 gggccggctc ggggaactga tcaccgaggt ccgcgtctcc cgcgtgcacc tgtcgtcccg
    23161 tcgaccgccg tgcatgcagc cgttgccgcg gccgatgtcc gcaccctttc cgagtccgcc
    23221 cgcacgtggc ggcctgtcgt gaacggcggg ttcaagtggg cgggtccagt ccgtacaggg
    23281 tgcggccgcc gaccagctcc cggccgctga ccaggtccgg cgcgatgcgg acgaagacct
    23341 ccacgggcca gggcacccag gaacgaggac cggtgcgaac gagttgctcg tgttccccgg
    23401 gatcggtgac caccgaggcg aggccggtga cgacgacgct ccagccggag tgcgtcacgg
    23461 cgtcgacttc gtcggcctcg aaagcgacca cggcaccgtc gacggcacgg accagctccg
    23521 aggaggccga cgtgcgcaac agcacggcac cgctcttttc caggacgaag ttgaccggca
    23581 ggacggcggg cagggcgtcg cgggtgtgca cgatgcggcc cacgggcgcg ttggccagcc
    23641 gctggaggct ctcctgtcgg ttcagctcgc ggaatccgtc gttgcggtac atcagccggg
    23701 tgtctctccg tgtgtcgtcc ggtgcgttgc gcgtactccc atcctgctgc ccgtcggcga
    23761 ccgcgacggc gagttcggcg gtgtgcgggg cgacgtgctc ggcgtggtac tcgacgaggc
    23821 cgacgccctg tcccgcacgt tcggcgagca gggcccggtg cccgcgccga gccggcgcgc
    23881 acacggtgtc cgcggccggg ccggcggagc gggagccggc cgagaggaag cgcaggcggc
    23941 ggttgtccgg tgacatctcc gcgtagagcc cctccagttg ctcgtggtcc ccggctcgac
    24001 ggcgcggata cggacggtgg tgccgtccgt gagcagcgcg tggactgcgg ggcggtgtgg
    24061 cgtgtcgtcc ttcatggcgg ttctccttcg agccgctcgg gtcctgtgtc ctgccgagcg
    24121 tccgtcacga cgtcggacgc gcccagggac cgaccggggg tgcccgcggg gcacgtccgg
    24181 cccccggtct tccgccggcc gtcccgggcg gcggcctcgg gcggtcatgt cgtgtcgggt
    24241 acgaccgcga ccggacaggc ggagtggtgc agaagggtgt gggcgacccg gccgaggcgg
    24301 tgcccgaact gcccgggacg ccgccggccg acgaccagca ggtccgcctc gtgggaggcg
    24361 gccgacagca ctcggctacc cggtccctcg gccgtacggc ggcgcaggcg cacgtccgcc
    24421 ggggcgtcgg cgagcgcggc ctccagctcc ttggccgccc gttcctcgtg aagacgctcg
    24481 ggcgtgcccg cgagcagcgg gtggtcgacc gtgtcgtggg tggggcatct ccatgcccgt
    24541 accgcgtcca gggcggcgcc gcgccgccgg gcctcctcgc aggcgaagcg caccgcagcg
    24601 gtgggcgcgt cggccacacc caccacgatg cggccgcgcc ggccgccacc ggcggcacgg
    24661 tcgtcgtggt ccccccgggt cacgacgacc ggacagtccg acatggtggc caccgtcagg
    24721 ctgacggagc cgagcagcag gccggcgagt tcgccccgcc cgcgggtgcc caggatcacg
    24781 gcggacgcgt tgcgcgcctc gcgcaggagg acgtactccg gttcctcggc cgtcgcttcg
    24841 gtggtgacgg cgaggtccgg gtggtgacga cgggcgcgac gggtggcgac ggcgaggatg
    24901 tcgtcggtgg tgacgtgacc ggacggcttg ccgagctccc gggcgaggga ggcgccctcg
    24961 tagcggtccc agcggtaggc gtggacgatc cgcaagggta cttcgtgcag ggcggcctcg
    25021 tcagccgccc agtcgactgc cccgaggctc gactcggagc cgtcgactcc gacgaccatg
    25081 ggcaggtaca tcgttctcag cctcccgcgt tgagatcgaa cacgatccgg gccttgacct
    25141 gtccgccgag gacctcgtcg atgcagtcgt tgacggcggc gagcggacgg gtctcccgga
    25201 tgaccttcgt gcggccctcg gcgtggagtt ggaagacctc ggcgagatcc tgccgggtgc
    25261 cgacgatgga gccgatgacc gaggtgccgt tgaggacggt gtcgaagatc gggacctgga
    25321 gggtgccgtg cgccggcagg gcaaccatga cgagtttccc gccgcgccgc agaccggagt
    25381 tgacggcctg gaaggcggcc gggttcaccg cgagggcgag ggcggcgtgc gcgccgccgt
    25441 gtcgcttcag ctcggcgccg acgtcctggg tgcgggcgtc gatgacgagg tcggcgccga
    25501 gttcccgggc gagttggagt ttgtcgtcgg tgacgtcgat cgcgacgacc cgcgctccgg
    25561 cgatcttcgc gtactgcacc gcgaggtgcc ccagtccgcc cacgcccgag acggcgacga
    25621 gctgggcggg cccgacttcg gcgaccttca gtgccttgta ggtggtgacg cccgcgcagg
    25681 tgagcggggc ggcgtcgagg gcgctgacgc cctcgggcac cggctgcgcg aagtcggccc
    25741 aggcaagcat cttctcggcg tacccgccgt cgcagccgta cccggtgttg acctggtcct
    25801 cgcacagggt ctcccagccg gaccggcagt gctcgcaccg cccgcacgcc ttgccgagcc
    25861 agggcacggc gacgcgttgt ccgacggcga ggtgggtcac gccgtcgccc agcttctcga
    25921 ccaggccgac gccctcgtgc ccggggacga acggcggggt gggcttgacc ggccagtcgc
    25981 cgtgggcggc gtggatgtcg gtgtggcaca ggccggatgc ctcgacggcc acgagcacct
    26041 gccccggacc gggctccggg tcgggcctgt cctcgatgac caggggcttg ccgaactccc
    26101 ggacgaccgc tgccttcatg gtcctgctcc ttctgtgctc gtcttcggtg ggccgcgtca
    26161 gtcgtgcgcg acgacggcga cgggggtggt ggcgtggtgc atgaccgcgt gggcgacggc
    26221 gccgatgtgc acaccgaacg ggctgcggcg gatacggcgg ccgacgacga cgagggaggc
    26281 gtcgcgggcc gcgtcgatga ggtgctcggc gggactgccg agccggcacg tctcggtcac
    26341 ctcgacgtcc gggtacttct cccgccaggg cagcagtgcc tcgccgagtg cttcggcctg
    26401 ggcgcgggcc agttcctcgc gcgggtcgaa cccggcggcg atgctgtagg tgtaggagga
    26461 cggcaggttc caggccctca cggcggtcag cggggcccgc cggcgccgcg cctcctcgaa
    26521 ggcgaaggag aggacggcct cgtccgggct gccggtgtcc agtcccacga ccacgggccg
    26581 gaagcccgtg gcggcggacg ggatgccggt ggggtccttg aggtgttcgt cggcggcctg
    26641 ttcccccgcg cggacgagga tcaccggcgt ctcggtgcgg gcgatcacgg actggccgac
    26701 ggatccgacc aggaagcccg tgagcccgct gagggcgcgc gagccgagca ccagcagttc
    26761 ggcgtcaagg gtgccggcga gcagggcgtc cgccggattc ccggtcgcct gctcggtggt
    26821 cacctcgacc cccgggtgcc gcagcctcaa gccctcggcc gtgtcccggg ggatccgttc
    26881 ggtccagtgc tggtgggtct cggcgccgag gagcggagcc tgggccatgg gctccggtac
    26941 cggctgccag acgtggagca gtcgtaccgg cacccggcgc agcgtgccct cgcgggccgc
    27001 ccactccgcg gctgcccggc tctcgggcga gccgtcgagt cctacggtga tcgtgcgggc
    27061 cattccggcc acctcctgtg tcttctgttc tgttctcagc gtctcttcgg gcggtctacg
    27121 ggggcagggg cctgtggtcc cgggacgggg ccgaccgtcc ctgcccgcag ggtgatggga
    27181 cgggtcctcg ggcgggcccg ccccaccggt cgtgttcagc gcagccacgc gtggtcgcgg
    27241 acgatcggga gcctggccca cagccggccc agtcccaggg cgtcaccggc cgagacagcg
    27301 gccagcgcga tcagcagcac cgcgtacagc acgtggtagt cggcgaacgg attcgtcgac
    27361 atgctcgccg acccgtcgga caggtgcttc gccggcggcc actccgccgc ccacatcagc
    27421 gccatcatca ccgtccccgc caccgcggcc ggccgcagcg ccacccccgc cgtcaacgcc
    27481 agcccgacgc cgagcaggcc cagcatgaac agccagtcgg cccacgccgc cccggcccac
    27541 gagtggaacg tcgactccat cggaccgacc gccacgtgcc cgaggaagcc ctcggtcggc
    27601 gaaccaccgt cgatccagcc cttgccggag gcggtggcgt aaccgaaccc gaacgtcttg
    27661 tccaggaacg cccacaggaa gacgaagccc atcagcaccc gggccgacgc gaagacgaaa
    27721 gcccgggcgg tgagcgcgcc ggcctccacc gaatctgccg cccccggcac ggatacggcg
    27781 ccgttacggc gcgaggacgg caggtggaaa cccgaaccac gatgcgtgga ctggtgcatg
    27841 gccatgacag tgaccccttc ggagaggatg cggttggttc ctgacaccac tcactctccc
    27901 gggccccgcc accccgcacc cgacgccgaa agtccgcacc ccgggggctc aacagcccca
    27961 atccgcgggg accttcggcc ggcggtgccc gtacggccct tacgcgcgcg tccgcgaggg
    28021 ccgaggcggg gaggtgttcg cccacctgcc cggccggcct cggacgtggg cgggaaggag
    28081 gagtaaggag gagttccgat gagttcgtca acctcgacgc cccggtcgcg gagcggctgg
    28141 tcgcgacggc cgtggccgcg ccgtccctgc gcaccaccca gccctggcgc ttccggctcg
    28201 ataccgacag ccgcacggtg cacatccacg ccgccgcgga tcgggcgcgg cgccacaccg
    28261 accaggtggg c
//
