LOCUS       NC_003888              25538 bp    DNA     linear   CON 03-AUG-2016
DEFINITION  Streptomyces coelicolor A3(2) chromosome, complete genome.
ACCESSION   NC_003888
VERSION     NC_003888.3
KEYWORDS    .
SOURCE      Streptomyces coelicolor A3(2)
  ORGANISM  Streptomyces coelicolor A3(2)
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL645882.
            On Jun 22, 2003 this sequence version replaced NC_003888.2.
            RefSeq Category: Reference Genome
            MOD: Model Organism
            UPR: UniProt Genome
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2023-11-22 14:16:39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 166500
            Orig. end    :: 192038
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25538
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15538]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15538
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..25538
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..25538
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     gene            391..837
                     /db_xref="GeneID:1095602"
                     /gene_synonym="SCJ1.27"
                     /locus_tag="SCO0178"
     CDS             391..837
                     /codon_start=1
                     /db_xref="GeneID:1095602"
                     /gene_synonym="SCJ1.27"
                     /locus_tag="SCO0178"
                     /note="SCJ1.27, unknown, len: 148 aa. Weak similarity to
                     Mycobacterium tuberculosis SW:YW23_MYCTU (EMBL; Z74025)
                     hypothetical 33.9 KD protein MTCY39.23C (317 aa), fasta
                     scores opt: 201 z-score: 231.7 E(): 1.5e-05 33.1% identity
                     in 136 aa overlap and Mycobacterium tuberculosis TR:O06189
                     (EMBL; Z95387)hypothetical 31.7 KD protein MTCY1A10.09C
                     (297 aa), fasta scores opt: 199 z-score: 229.8 E(): 1.9e-05
                     33.3% identity in 153 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_624514.1"
                     /transl_table=11
                     /translation="MLVAQALSAAAVVVGHRGPHPFQGALIGSLATGLAAHSECPVVVV
                     GEPENPAGPVALGVDGSAAGAAAVRLPGDFRAGCGHHRRARLDGLERADAASPRRETEP
                     YACEPGMLAAEEGRLLAETLAGMCARYPEVRVERSTVHGVHGRR"
     PFAM_domain     394..525
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0178_0047"
                     /evalue="5.10E-08"
                     /label="SCO0178"
                     /locus_tag="SCO0178"
                     /protein_end="45"
                     /protein_start="1"
                     /score="33.7"
                     /tool="antismash"
                     /translation="LVAQALSAAAVVVGHRGPHPFQGALIGSLATGLAAHSECPVVVV"
     gene            complement(944..2014)
                     /db_xref="GeneID:1095603"
                     /gene_synonym="SCJ1.28c"
                     /locus_tag="SCO0179"
     CDS             complement(944..2014)
                     /NRPS_PKS="Domain: PKS_ER (23-337). E-value: 4.7e-10.
                     Score: 30.9. Matches aSDomain:
                     nrpspksdomains_SCO0179_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:1095603"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 366.7; E-value:
                     1.7e-111)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCJ1.28c"
                     /locus_tag="SCO0179"
                     /note="SCJ1.28c,possible zinc-containing dehydrogenase,
                     len: 356 aa. Similar to many including: Thermoanaerobacter
                     brockii SW:ADH_THEBR (EMBL; X64841) NADP-dependent alcohol
                     dehydrogenase (EC 1.1.1.2) (352 aa), fasta scores opt: 556
                     z-score: 601.1 E(): 4e-26 33.7% identity in 338 aa overlap
                     and Halobacterium volcanii TR:O34179 (EMBL; U95372)
                     dehydrogenase (389 aa), fasta scores opt: 715 z-score:
                     770.1 E(): 0 37.0% identity in 351 aa overlap. Contains a
                     Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases and a PS00059 Zinc-containing alcohol
                     dehydrogenases signature"
                     /product="zinc-containing dehydrogenase"
                     /protein_id="NP_624515.1"
                     /sec_met_domain="ADH_N (E-value: 2.1e-29, bitscore: 100.4,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.2e-25, bitscore:
                     87.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGYVFHGPGRSAWEDIPDPELKEPTDAIVRVDAVTICGTDLHIL
                     KGDVPEVRPGTVLGHEAVGEIVEVGTDVRTVRPGDRVLVSCITACGRCRYCREGVYGQC
                     LGGGGWILGHLINGTQAEYVRVPYADLSVHSLPGAVTDEDAVLLADIFPTAYEVGVLNG
                     RVSPGDTVVVVGAGPIGLAAVATARLFAPERIVVVDLATARLEAARKLGAEAVADARED
                     PEQLVADLTGGLGADVVIEAVGVPETFEMCTRVVRPGGHVANVGVHGRPATLHLEDLWS
                     KNVTVTTGLVDTRSTPTLLRMAASGRLPTGQLVTHTFPLERMEEAYEVFSAAADTGALK
                     VVLGGPKREVVAANAV"
     misc_feature    complement(983..1987)
                     /gene_synonym="SCJ1.28c"
                     /locus_tag="SCO0179"
                     /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases, score 236.60, E-value 3.4e-67"
     aSDomain        complement(1004..1945)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO0179_PKS_ER.1"
                     /evalue="4.70E-10"
                     /label="SCO0179_PKS_ER.1"
                     /locus_tag="SCO0179"
                     /protein_end="337"
                     /protein_start="23"
                     /score="30.9"
                     /tool="antismash"
                     /translation="EPTDAIVRVDAVTICGTDLHILKGDVPEVRPGTVLGHEAVGEIVE
                     VGTDVRTVRPGDRVLVSCITACGRCRYCREGVYGQCLGGGGWILGHLINGTQAEYVRVP
                     YADLSVHSLPGAVTDEDAVLLADIFPTAYEVGVLNGRVSPGDTVVVVGAGPIGLAAVAT
                     ARLFAPERIVVVDLATARLEAARKLGAEAVADAREDPEQLVADLTGGLGADVVIEAVGV
                     PETFEMCTRVVRPGGHVANVGVHGRPATLHLEDLWSKNVTVTTGLVDTRSTPTLLRMAA
                     SGRLPTGQLVTHTFPLERMEEAYEVFSAAADTG"
     PFAM_domain     complement(1115..1483)
                     /aSDomain="ADH_zinc_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00107.29"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0179_0049"
                     /evalue="1.10E-24"
                     /label="SCO0179"
                     /locus_tag="SCO0179"
                     /protein_end="300"
                     /protein_start="177"
                     /score="87.1"
                     /tool="antismash"
                     /translation="PIGLAAVATARLFAPERIVVVDLATARLEAARKLGAEAVADARED
                     PEQLVADLTGGLGADVVIEAVGVPETFEMCTRVVRPGGHVANVGVHGRPATLHLEDLWS
                     KNVTVTTGLVDTRSTPTLL"
     PFAM_domain     complement(1625..1939)
                     /aSDomain="ADH_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08240.15"
                     /description="Alcohol dehydrogenase GroES-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0179_0048"
                     /evalue="5.20E-29"
                     /label="SCO0179"
                     /locus_tag="SCO0179"
                     /protein_end="130"
                     /protein_start="25"
                     /score="100.4"
                     /tool="antismash"
                     /translation="TDAIVRVDAVTICGTDLHILKGDVPEVRPGTVLGHEAVGEIVEVG
                     TDVRTVRPGDRVLVSCITACGRCRYCREGVYGQCLGGGGWILGHLINGTQAEYVRVPYA
                     D"
     misc_feature    complement(1796..1840)
                     /gene_synonym="SCJ1.28c"
                     /locus_tag="SCO0179"
                     /note="PS00059 Zinc-containing alcohol dehydrogenases
                     signature, GHE.{2}G.{5}[GA].{2}[IVSAC], info count = 21.8"
     regulatory      complement(2028..2033)
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(2150..2164)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.9"
                     /tool="antismash"
     gene            complement(2205..3056)
                     /db_xref="GeneID:1095604"
                     /gene_synonym="SCJ1.29c"
                     /locus_tag="SCO0180"
     CDS             complement(2205..3056)
                     /codon_start=1
                     /db_xref="GeneID:1095604"
                     /gene_synonym="SCJ1.29c"
                     /locus_tag="SCO0180"
                     /note="SCJ1.29c, unknown, len: 283 aa. Similar to many
                     including: Mycobacterium tuberculosis TR:O53472 (EMBL;
                     AL021899) hypothetical 31.5 KD protein (294 aa), fasta
                     scores opt: 329 z-score: 389.0 E(): 2.6e-14 32.1% identity
                     in 293 aa overlap and Mycobacterium tuberculosis TR:O06189
                     (EMBL; Z95387) hypothetical 31.7 KD protein (297 aa), fasta
                     scores opt: 330 z-score: 390.1 E(): 2.3e-14 31.8% identity
                     in 296 aa overlap. Also similar to S. coelicolor SCJ1.16c
                     (294 aa), fasta scores opt: 806 z-score: 748.1 E():0 46.1%
                     identity in 295 aa overlap. Contains a Pfam match to entry
                     PF00582 Usp, Universal stress protein family"
                     /product="hypothetical protein"
                     /protein_id="NP_624516.1"
                     /transl_table=11
                     /translation="MYLPLVVGVDGSEPSLRAVDWAADEAALHAVPLWVVFGDLWERYE
                     GAALAREPGKPSTDMQADDILAAAAIRAGRRHPDLVVTTETVPDEAEHALICAGRNASM
                     IVMGSRGRSGIADRLLGSVSRTVAAGSDCPVVVLRGNHDNRAIGGRNGRIVVGVGEVSA
                     SVLRLAFMEARLRQVPVAAVRAWRCPAHETIDHPLPAGEPARRYEERAARELEAALEDA
                     PPDVAVRRYTVEGPARAVLPAASAEAGLLVIGRRTQGRLGRVAHAVLHRSACPVVVVPE
                     RT"
     PFAM_domain     complement(2217..2603)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0180_0051"
                     /evalue="2.40E-13"
                     /label="SCO0180"
                     /locus_tag="SCO0180"
                     /protein_end="280"
                     /protein_start="151"
                     /score="50.9"
                     /tool="antismash"
                     /translation="GRIVVGVGEVSASVLRLAFMEARLRQVPVAAVRAWRCPAHETIDH
                     PLPAGEPARRYEERAARELEAALEDAPPDVAVRRYTVEGPARAVLPAASAEAGLLVIGR
                     RTQGRLGRVAHAVLHRSACPVVVVP"
     PFAM_domain     complement(2640..3056)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0180_0050"
                     /evalue="1.30E-25"
                     /label="SCO0180"
                     /locus_tag="SCO0180"
                     /protein_end="139"
                     /protein_start="0"
                     /score="90.7"
                     /tool="antismash"
                     /translation="MYLPLVVGVDGSEPSLRAVDWAADEAALHAVPLWVVFGDLWERYE
                     GAALAREPGKPSTDMQADDILAAAAIRAGRRHPDLVVTTETVPDEAEHALICAGRNASM
                     IVMGSRGRSGIADRLLGSVSRTVAAGSDCPVVVLR"
     misc_feature    complement(2643..2981)
                     /gene_synonym="SCJ1.29c"
                     /locus_tag="SCO0180"
                     /note="Pfam match to entry PF00582 Usp, Universal stress
                     protein family, score 34.80, E-value 2e-06"
     regulatory      complement(3063..3070)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(3084..4070)
                     /db_xref="GeneID:1095605"
                     /gene_synonym="SCJ1.30c"
                     /locus_tag="SCO0181"
     CDS             complement(3084..4070)
                     /codon_start=1
                     /db_xref="GeneID:1095605"
                     /gene_synonym="SCJ1.30c"
                     /locus_tag="SCO0181"
                     /note="SCJ1.30c, unknown, len: 328 aa. Similar to many
                     including: Mycobacterium tuberculosis SW:YW23_MYCTU (EMBL;
                     Z74025) hypothetical 33.9 KD protein MTCY39.23C (317 aa)
                     fasta scores opt: 382 z-score: 439.2 E(): 4.2e-17 32.6%
                     identity in 319 aa overlap and Mycobacterium tuberculosis
                     TR:O53472 (EMBL; AL021899) hypothetical 31.5 KD protein
                     (294 aa), fasta scores opt: 382 z-score: 439.2 E(): 4.2e-17
                     32.6% identity in 319 aa overlap. Contains a Pfam match to
                     entry PF00582 Usp, Universal stress protein family."
                     /product="hypothetical protein"
                     /protein_id="NP_624517.1"
                     /transl_table=11
                     /translation="MSEDEWPYPGAQLRDTLESEGPTREVRDMTRTITVGIDGSPESHA
                     AAEWAAREAELRDLPVRLLHVWEPAPAVLAQDSILGAKTHQHWTERVPQKVGEGLRLRH
                     PGVVVTSDQRSGPPADTLVRDADGAELLVLGSRAPSGLGGFLAGSVGQSVIAHSETPVV
                     LVRAGEQAAGEHVVDSVGVPPAANRRRPVVVGLDIGSPDDGVLSFAFDEAQRRGTAVHV
                     VSGWRPPPYYPSLTAGGVPDQGVARRKAADLTRLLLPWRQSYPDVEVVEASRPGSPADL
                     LAEASHEASLVVVGRRIRPSPLGVHIGAVAHAVLHRVSAPVAVVAHP"
     misc_feature    complement(3096..3419)
                     /gene_synonym="SCJ1.30c"
                     /locus_tag="SCO0181"
                     /note="Pfam match to entry PF00582 Usp, Universal stress
                     protein family, score 42.80, E-value 7.5e-09"
     PFAM_domain     complement(3096..3503)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0181_0053"
                     /evalue="1.80E-17"
                     /label="SCO0181"
                     /locus_tag="SCO0181"
                     /protein_end="325"
                     /protein_start="189"
                     /score="64.3"
                     /tool="antismash"
                     /translation="RPVVVGLDIGSPDDGVLSFAFDEAQRRGTAVHVVSGWRPPPYYPS
                     LTAGGVPDQGVARRKAADLTRLLLPWRQSYPDVEVVEASRPGSPADLLAEASHEASLVV
                     VGRRIRPSPLGVHIGAVAHAVLHRVSAPVAVV"
     PFAM_domain     complement(3573..3986)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0181_0052"
                     /evalue="3.20E-26"
                     /label="SCO0181"
                     /locus_tag="SCO0181"
                     /protein_end="166"
                     /protein_start="28"
                     /score="92.7"
                     /tool="antismash"
                     /translation="MTRTITVGIDGSPESHAAAEWAAREAELRDLPVRLLHVWEPAPAV
                     LAQDSILGAKTHQHWTERVPQKVGEGLRLRHPGVVVTSDQRSGPPADTLVRDADGAELL
                     VLGSRAPSGLGGFLAGSVGQSVIAHSETPVVLVR"
     gene            complement(4156..4380)
                     /db_xref="GeneID:1095606"
                     /gene_synonym="SCJ1.31c"
                     /locus_tag="SCO0182"
     CDS             complement(4156..4380)
                     /codon_start=1
                     /db_xref="GeneID:1095606"
                     /gene_synonym="SCJ1.31c"
                     /locus_tag="SCO0182"
                     /note="SCJ1.31c, doubtful CDS, len: 74 aa. Contains a
                     TTA/leucine codon, possible target for bldA regulation."
                     /product="hypothetical protein"
                     /protein_id="NP_624518.1"
                     /transl_table=11
                     /translation="MCRAAVGVLEAGARREGVTCGTYGLWDGVTAWREPRSSMPDLTQV
                     LKPIEGSDLVPAASVVAAHAEDRLKGEGH"
     misc_feature    complement(4306..4308)
                     /gene_synonym="SCJ1.31c"
                     /locus_tag="SCO0182"
                     /note="TTA/leucine codon, possible target for bldA
                     regulation."
     misc_feature    complement(4306..4308)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4411..5658
                     /db_xref="GeneID:1095607"
                     /gene_synonym="SCJ1.32"
                     /locus_tag="SCO0183"
     CDS             4411..5658
                     /codon_start=1
                     /db_xref="GeneID:1095607"
                     /gene_synonym="SCJ1.32"
                     /locus_tag="SCO0183"
                     /note="SCJ1.32, unknown,len: 415 aa. Likely to have arisen
                     as a result of a duplication of SCF43A.31/32, followed by a
                     deletion event generating a possible CDS with the 5' coding
                     sequence of SCF43A.31 and the 3' coding sequence of
                     SCF43A.32. Similarity scores are as follows: to
                     Streptomyces coelicolor TR:CAB48918 (EMBL; AL096837)
                     oxidoreductase SCF43A.31 (520 aa), fasta scores opt: 1191
                     z-score: 1365.3 E(): 0 64.2% identity in 307 aa overlap and
                     to Streptomyces coelicolor TR:CAB48919(EMBL; AL096837)
                     deoxyribodipyrimidine photolyase SCF43A.32 (458 aa), opt:
                     909 z-score: 1043.2 E(): 0 45.7% identity in 418 aa
                     overlap. Contains a PS00394 DNA photolyases class 1
                     signature 1 and a PS00691 DNA photolyases class 1 signature
                     2."
                     /product="deoxiribopirymidine photolyase"
                     /protein_id="NP_624519.1"
                     /transl_table=11
                     /translation="MRRIVYLGGLTPRGVPERTLSPHLRSRAEVGPILVRDVLHYLAGA
                     ATMPDDIDRAFDVGGPDVPTYREMMRRHATVSGLRRRIIVPAPVLTPGLSSHWVGLVTP
                     VPASIARPLTESLRHEVVCQEHDIARYVPDAPGRPLPFDVALTLALRRVREAQVATRWS
                     SASVPGAPSDPLPTDPDWAGGSLYEDERHLPVDASPEALWKVVEGIGGDNGWYSFPPAW
                     AVRGWLDRFVGGVGLRRGRRDAQRLHPARPVAWRGGRRRGHRRLAGRTGYPVVDAAMRQ
                     LRHQGWMHNRARLLVASFLTKTLYVDWRIGARHFLDLLVDGDVVNNQLNWQWAAGTGTD
                     TRPHRVLNPLVQARRFDPDGVYVRRWVPELRSVEGGKVHEPWRLAAAERGELDYPDPLV
                     ELADGLARFKHARGRD"
     PFAM_domain     4951..5166
                     /aSDomain="DUF2867"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF11066.11"
                     /description="Protein of unknown function (DUF2867)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0183_0054"
                     /evalue="3.90E-13"
                     /label="SCO0183"
                     /locus_tag="SCO0183"
                     /protein_end="252"
                     /protein_start="180"
                     /score="50.1"
                     /tool="antismash"
                     /translation="WAGGSLYEDERHLPVDASPEALWKVVEGIGGDNGWYSFPPAWAVR
                     GWLDRFVGGVGLRRGRRDAQRLHPARP"
     PFAM_domain     5209..5631
                     /aSDomain="FAD_binding_7"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03441.17"
                     /description="FAD binding domain of DNA photolyase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0183_0055"
                     /evalue="2.70E-58"
                     /label="SCO0183"
                     /locus_tag="SCO0183"
                     /protein_end="407"
                     /protein_start="266"
                     /score="197.0"
                     /tool="antismash"
                     /translation="AGRTGYPVVDAAMRQLRHQGWMHNRARLLVASFLTKTLYVDWRIG
                     ARHFLDLLVDGDVVNNQLNWQWAAGTGTDTRPHRVLNPLVQARRFDPDGVYVRRWVPEL
                     RSVEGGKVHEPWRLAAAERGELDYPDPLVELADGLAR"
     misc_feature    5218..5256
                     /gene_synonym="SCJ1.32"
                     /locus_tag="SCO0183"
                     /note="PS00394 DNA photolyases class 1 signature 1"
     misc_feature    5278..5337
                     /gene_synonym="SCJ1.32"
                     /locus_tag="SCO0183"
                     /note="PS00691 DNA photolyases class 1 signature 2"
     gene            5670..7484
                     /db_xref="GeneID:1095608"
                     /gene_synonym="SCJ1.33"
                     /locus_tag="SCO0184"
     CDS             5670..7484
                     /codon_start=1
                     /db_xref="GeneID:1095608"
                     /gene_synonym="SCJ1.33"
                     /locus_tag="SCO0184"
                     /note="SCJ1.33 unknown, len: 604 aa. Highly similar to
                     Synechocystis sp. (strain PCC6803) TR:P74080 (EMBL;D90912)
                     hypothetical 58.1 KD protein (504 aa), fasta scores opt:
                     931 z-score: 996.4 E(): 0 38.8% identity in 479 aa overlap
                     and Methanobacterium thermoautotrophicum TR:O27804
                     (EMBL;AE000932) conserved protein MTH1776 (491 aa), fasta
                     scores opt: 572 z-score: 613.5 E(): 8.1e-27 31.7% identity
                     in 483 aa overlap. Also shares a low level of similarity
                     with Streptomyces coelicolor TR:CAB48919 (EMBL;AL096837)
                     deoxyribodipyrimidine photolyase SCF43A.32 (458 aa), fasta
                     scores opt: 176 z-score: 191.4 E(): 0.0026 31.1% identity
                     in 219 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_624520.1"
                     /transl_table=11
                     /translation="MHWLFGDQLGPHFLTPGEEGPGPETPLLMIEARSVFRRRRFHRAK
                     AHLVLSAMRHRAAEPGDRVTYVRADTYRQGLARTARGRPVGVHHPTSHAALRLVRALPQ
                     VTVGPARGFLVPMTGFAAWAEGHGGKRLRQEDFYRWVRRGHGLLMDGEQPAAGRWNLDH
                     DNREPPPREAASLQVGRPYRPREDDIDEEVRHDLDRWERDGDVSFVGRDGPRLFPATRT
                     EGLRALRRFVEHRLATFGPHEDAMLAADPVMSHSLLSSTLNLGPLDPVECVERAERAWR
                     EGRAPLNSVEGFVRQIAGWREYVWQLYWYFGEGYRRSNALGHTAPLPDWWNRLDADAVR
                     ANCLRTVLAQVRDTGWTHHIPRLMVLGSHALQRGWDPAAVTNWFHRCFVDGYDWVMLPN
                     VVGMSQYADGGRMTTKPYTSAGAYVNRMSDLCGPCGYRPGDRTCEHACPYTTGYWAFLD
                     RHRELLAGNQRVARPVRQSDRLADLPDVCAQGTRGVTHRHEPPPLRRRGEVGPHPVPER
                     AEVSASTTGHPAEAVACGQPRVRRGCACLDCRRWWPRRPNRSTTPSPRPMRRTRSTPSS
                     GGYWTNGCATAVPSTPSSPGNWPTVSRR"
     PFAM_domain     5676..6266
                     /aSDomain="DPRP"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04244.16"
                     /description="Deoxyribodipyrimidine photo-lyase-related
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0184_0056"
                     /evalue="3.50E-31"
                     /label="SCO0184"
                     /locus_tag="SCO0184"
                     /protein_end="199"
                     /protein_start="2"
                     /score="108.9"
                     /tool="antismash"
                     /translation="WLFGDQLGPHFLTPGEEGPGPETPLLMIEARSVFRRRRFHRAKAH
                     LVLSAMRHRAAEPGDRVTYVRADTYRQGLARTARGRPVGVHHPTSHAALRLVRALPQVT
                     VGPARGFLVPMTGFAAWAEGHGGKRLRQEDFYRWVRRGHGLLMDGEQPAAGRWNLDHDN
                     REPPPREAASLQVGRPYRPREDDIDEEVRHDLDR"
     gene            7268..8446
                     /db_xref="GeneID:1095609"
                     /gene_synonym="crtB; SCJ1.34"
                     /locus_tag="SCO0185"
     CDS             7268..8446
                     /codon_start=1
                     /db_xref="GeneID:1095609"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 223.8; E-value:
                     4.3e-68)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="crtB; SCJ1.34"
                     /locus_tag="SCO0185"
                     /note="SCJ1.34, crtB, possible geranylgeranyl pyrophosphate
                     synthase, len: 392 aa. Shares a high level of similarity
                     with Streptomyces griseus TR:Q54193 (EMBL:L37405)
                     geranylgeranyl pyrophosphate synthase (425 aa), fasta
                     scores: opt: 964 z-score: 1076.9 E(): 0 48.0% identity in
                     381 aa overlap and Mycobacterium tuberculosis TR:O53507
                     (EMBL:AL021957) geranylgeranyl pyrophosphate synthase (352
                     aa), fasta scores opt: 742 z-score: 831.2 E(): 0 43.0%
                     identity in 328 aa overlap. Contains a PS00723 Polyprenyl
                     synthetases signature 1"
                     /product="geranylgeranyl pyrophosphate synthase"
                     /protein_id="NP_624521.1"
                     /transl_table=11
                     /translation="MRTTESEKGLRMPGLPPMVAPPAEQVDDPVTATDAANAVDAVLRG
                     VLDERLRHCRAVDPLFARELADRLAALTARGGKRLRTAFAHCGWRAAGGSGDATAVLRT
                     GAALELLQACALVHDDVMDGSVQRRGAPALHVDLARGHWAAGMHGSSESFGTSAAVLTG
                     DLALAWADDLLTETALGTPHGPRLHGEWRAMRTEMVAGQYRDLHAQAARSSGVDEALAI
                     ATLKSALYTVARPLALGAVLAGAADGDALEALRAAGRCAGLAFQLRDDLLGAFGDPALT
                     GKPADDDLRSRKLTYLLAVAVRLADAADDHLAAAALAPDADPKSEKAVRQVRSALVRTG
                     ARDLVETKIGELTDMSLAHFDRCGARPAVRHEFAALIGRATGAVPRGTGEVV"
     PFAM_domain     7460..8266
                     /aSDomain="polyprenyl_synt"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00348.20"
                     /db_xref="GO:0008299"
                     /description="Polyprenyl synthetase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0185_0057"
                     /evalue="1.20E-45"
                     /gene_ontologies="GO:0008299: isoprenoid biosynthetic
                     process"
                     /label="SCO0185"
                     /locus_tag="SCO0185"
                     /protein_end="333"
                     /protein_start="64"
                     /score="155.7"
                     /tool="antismash"
                     /translation="LADRLAALTARGGKRLRTAFAHCGWRAAGGSGDATAVLRTGAALE
                     LLQACALVHDDVMDGSVQRRGAPALHVDLARGHWAAGMHGSSESFGTSAAVLTGDLALA
                     WADDLLTETALGTPHGPRLHGEWRAMRTEMVAGQYRDLHAQAARSSGVDEALAIATLKS
                     ALYTVARPLALGAVLAGAADGDALEALRAAGRCAGLAFQLRDDLLGAFGDPALTGKPAD
                     DDLRSRKLTYLLAVAVRLADAADDHLAAAALAPDADPKSEKAVRQVR"
     misc_feature    7613..7657
                     /gene_synonym="crtB; SCJ1.34"
                     /locus_tag="SCO0185"
                     /note="PS00723 Polyprenyl synthetases signature 1,
                     [LIVM]{2}.DD.{2,4}D.{4}RR[GH], info count = 26.9"
     gene            8443..10014
                     /db_xref="GeneID:1095610"
                     /gene_synonym="crtE; SCJ1.35"
                     /locus_tag="SCO0186"
     CDS             8443..10014
                     /codon_start=1
                     /db_xref="GeneID:1095610"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 491.4; E-value: 5.8e-149)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="crtE; SCJ1.35"
                     /locus_tag="SCO0186"
                     /note="SCJ1.35, crtE, probable phytoene dehydrogenase
                     (phytoene desaturase) (hypothetical protein), len: 523 aa.
                     High level of similarity to Streptomyces griseus
                     SW:CRTI_STRGR (EMBL; L37405) phytoene dehydrogenase (EC
                     1.3.-.-) (phytoene desaturase) (507 aa), fasta scores opt:
                     2459 z-score: 2615.3 E(): 0; 74.5% identity in 501 aa
                     overlap and Streptomyces setonii SW:CRTI_STRSE (EMBL;
                     D55723) phytoene dehydrogenase (EC 1.3.-.-) (phytoene
                     desaturase) (508 aa), fasta scores opt: 2455 z-score:
                     2611.0 E(): 0; 74.3% identity in 498 aa overlap. Contains a
                     PS00982 Bacterial-type phytoene dehydrogenase signature"
                     /product="phytoene dehydrogenase"
                     /protein_id="NP_624522.1"
                     /sec_met_domain="DAO (E-value: 9.7e-17, bitscore: 60.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVPGPTGHVVVVGAGLSGLACALHLLGAGRRVTVVERDAGPGG
                     RSGRVRLGGYELDTGPTVLTMPHLADEAFAAVGDSLRRRVELTALDPAYRACFADGSAL
                     DVHTDGEAMEAEVRRFAGPAQAAGYRDLRRWLERLYRAQMRRFIDTNFDSPLQLLHPDL
                     ARLAALGGFGRLDGRIGRFLSDERLRRVFSFQALYAGVAPARALAAYAVIAYMDTVAGV
                     WFPKGGMHALPRAMADAAATAGADLRWSAEVKALERSAGRVRAVHLASGERIACDAVVL
                     TCELSTAYGLLGRAPRRPARLRHSPSAVILHAGTDRTWPHLAHHTLSFGAAWERTFEEL
                     TRTGELMSDPSLLITRPTTHDPALAPPGRHLHYVLAPCPNTDVGPDAVAWRDLGPRYRE
                     SLVGVLESRGLEGFADSVQEELLVTPLDWDAQGHAAGSPFSVSHTFAQTGPFRPRNLVR
                     GLDNVVLAGCGTTPGVGVPTVLVSGKLAAARVTGGAGSRPARTRRSPAVSDPCPAPVPA
                     GADDPS"
     aSDomain        8473..9954
                     /aSDomain="TIGR02734"
                     /aSTool="tigrfam"
                     /description="crtI_fam: phytoene desaturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO0186_0003"
                     /evalue="2.30E-179"
                     /identifier="TIGR02734"
                     /label="SCO0186"
                     /locus_tag="SCO0186"
                     /protein_end="504"
                     /protein_start="10"
                     /score="595.3"
                     /tool="antismash"
                     /translation="VVVVGAGLSGLACALHLLGAGRRVTVVERDAGPGGRSGRVRLGGY
                     ELDTGPTVLTMPHLADEAFAAVGDSLRRRVELTALDPAYRACFADGSALDVHTDGEAME
                     AEVRRFAGPAQAAGYRDLRRWLERLYRAQMRRFIDTNFDSPLQLLHPDLARLAALGGFG
                     RLDGRIGRFLSDERLRRVFSFQALYAGVAPARALAAYAVIAYMDTVAGVWFPKGGMHAL
                     PRAMADAAATAGADLRWSAEVKALERSAGRVRAVHLASGERIACDAVVLTCELSTAYGL
                     LGRAPRRPARLRHSPSAVILHAGTDRTWPHLAHHTLSFGAAWERTFEELTRTGELMSDP
                     SLLITRPTTHDPALAPPGRHLHYVLAPCPNTDVGPDAVAWRDLGPRYRESLVGVLESRG
                     LEGFADSVQEELLVTPLDWDAQGHAAGSPFSVSHTFAQTGPFRPRNLVRGLDNVVLAGC
                     GTTPGVGVPTVLVSGKLAAARVTGGAGSRPARTRRS"
     PFAM_domain     8494..9912
                     /aSDomain="Amino_oxidase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01593.27"
                     /db_xref="GO:0016491"
                     /description="Flavin containing amine oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0186_0058"
                     /evalue="2.50E-58"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO0186"
                     /locus_tag="SCO0186"
                     /protein_end="490"
                     /protein_start="17"
                     /score="198.6"
                     /tool="antismash"
                     /translation="LSGLACALHLLGAGRRVTVVERDAGPGGRSGRVRLGGYELDTGPT
                     VLTMPHLADEAFAAVGDSLRRRVELTALDPAYRACFADGSALDVHTDGEAMEAEVRRFA
                     GPAQAAGYRDLRRWLERLYRAQMRRFIDTNFDSPLQLLHPDLARLAALGGFGRLDGRIG
                     RFLSDERLRRVFSFQALYAGVAPARALAAYAVIAYMDTVAGVWFPKGGMHALPRAMADA
                     AATAGADLRWSAEVKALERSAGRVRAVHLASGERIACDAVVLTCELSTAYGLLGRAPRR
                     PARLRHSPSAVILHAGTDRTWPHLAHHTLSFGAAWERTFEELTRTGELMSDPSLLITRP
                     TTHDPALAPPGRHLHYVLAPCPNTDVGPDAVAWRDLGPRYRESLVGVLESRGLEGFADS
                     VQEELLVTPLDWDAQGHAAGSPFSVSHTFAQTGPFRPRNLVRGLDNVVLAGCGTTPGVG
                     VPTVLVSGKLAAARV"
     misc_feature    9826..9888
                     /gene_synonym="crtE; SCJ1.35"
                     /locus_tag="SCO0186"
                     /note="PS00982 Bacterial-type phytoene dehydrogenase
                     signature"
     gene            10001..10996
                     /db_xref="GeneID:1095611"
                     /gene_synonym="crtI; SCJ1.36"
                     /locus_tag="SCO0187"
     CDS             10001..10996
                     /codon_start=1
                     /db_xref="GeneID:1095611"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /gene_synonym="crtI; SCJ1.36"
                     /locus_tag="SCO0187"
                     /note="SCJ1.36, crtI, probable phytoene synthase, len: 331
                     aa. Shares a high level of similarity with Streptomyces
                     griseus SW:CRTB_STRGR (EMBL; L37405) phytoene synthase (342
                     aa), fasta scores opt: 1388 z-score: 1657.5 E(): 0 67.6%
                     identity in 343 aa overlap and Mycobacterium marinum TR:
                     O05423 (EMBL; U92075) phytoene synthase (319 aa), fasta
                     scores opt: 996 z-score: 1191.5 E():0 52.2% identity in 316
                     aa overlap. Contains a PS01045 Squalene and phytoene
                     synthases signature 2 and a Pfam match to entry PF00494
                     SQS_PSY, Squalene and phytoene synthases"
                     /product="phytoene synthase"
                     /protein_id="NP_624523.1"
                     /sec_met_domain="phytoene_synt (E-value: 7.3e-127,
                     bitscore: 421.0, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRELDAAGITDPLLRAAYTRCRRLNARHGKTYFLATRLLPLER
                     RSAVHALYGFARWADDIVDDLDRHRTAGERDRALRRLESDLADGLRTGTGREPVVRAVA
                     DTADRYDIDHVLFADFLSSMRADLTVTHYPTYADLQAYVHGSAAVIGLQMLPVLGTVTD
                     RKEAAPHAAALGVAFQLTNFLRDVGEDLDRGRVYLPGSLLAAHGVDRPLLEWSRRTGRR
                     DRRIRAALVAAEAMTRRVYRTAEPGIAMLDPRVRPCIRAAFTLYGGILDAIAEQDYTVL
                     HRRAVVSRRRRAATAAEGVLCVAAARWRARTSPRVEAAGGPAAEWQGPVR"
     PFAM_domain     10085..10873
                     /aSDomain="SQS_PSY"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00494.22"
                     /db_xref="GO:0009058"
                     /description="Squalene/phytoene synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0187_0059"
                     /evalue="5.70E-61"
                     /gene_ontologies="GO:0009058: biosynthetic process"
                     /label="SCO0187"
                     /locus_tag="SCO0187"
                     /protein_end="291"
                     /protein_start="28"
                     /score="206.4"
                     /tool="antismash"
                     /translation="RHGKTYFLATRLLPLERRSAVHALYGFARWADDIVDDLDRHRTAG
                     ERDRALRRLESDLADGLRTGTGREPVVRAVADTADRYDIDHVLFADFLSSMRADLTVTH
                     YPTYADLQAYVHGSAAVIGLQMLPVLGTVTDRKEAAPHAAALGVAFQLTNFLRDVGEDL
                     DRGRVYLPGSLLAAHGVDRPLLEWSRRTGRRDRRIRAALVAAEAMTRRVYRTAEPGIAM
                     LDPRVRPCIRAAFTLYGGILDAIAEQDYTVLHRRAVVSRRR"
     misc_feature    10145..10915
                     /gene_synonym="crtI; SCJ1.36"
                     /locus_tag="SCO0187"
                     /note="Pfam match to entry PF00494 SQS_PSY, Squalene and
                     phytoene synthases, score 253.20, E-value 3.5e-72"
     misc_feature    10520..10597
                     /gene_synonym="crtI; SCJ1.36"
                     /locus_tag="SCO0187"
                     /note="PS01045 Squalene and phytoene synthases signature 2"
     gene            10993..12003
                     /db_xref="GeneID:1095612"
                     /gene_synonym="crtV; SCJ1.37"
                     /locus_tag="SCO0188"
     CDS             10993..12003
                     /codon_start=1
                     /db_xref="GeneID:1095612"
                     /gene_synonym="crtV; SCJ1.37"
                     /locus_tag="SCO0188"
                     /note="SCJ1.37, crtV, probable methylesterase, len: 336 aa.
                     Highly similar to Streptomyces griseus TR:P72448 (EMBL;
                     X95596) methylesterase (338 aa), fasta scores opt: 1315
                     z-score: 1538.7 E(): 0 60.5% identity in 337 aa overlap"
                     /product="methylesterase"
                     /protein_id="NP_624524.1"
                     /transl_table=11
                     /translation="MSGRRGGRRWSPPVRRRGAGPDWAAQTPTWRQARPSLIADALERA
                     SARPSGNWFVVGASRQVRAGDRPYGRTVGGVEVVLWRSDDGEPRAGSGICPHLGAPLRD
                     SRVVCGTLVCHWHGLALDGSASAGWRPFPVHDDGVLVWVRLDEVGGEEPTERPVVPTRP
                     ATGRGVDSVFTATGRCEPQDVVANRLDPWHGSWFHPYSFVDLSVVREPQGGEDDAFVVD
                     VSFRVAGRLVVPVRAEFTAPEPRTVVMRITDGEGATSVVETHATPLTGPDHERPRTAVV
                     EAVVAASDRPGFALARAAAPVLRPLMRRTAGRLWRDDLAYAERRWALRSTGRFPG"
     PFAM_domain     11146..11382
                     /aSDomain="Rieske"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00355.29"
                     /db_xref="GO:0051537"
                     /description="Rieske [2Fe-2S] domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0188_0060"
                     /evalue="1.90E-13"
                     /gene_ontologies="GO:0051537: 2 iron, 2 sulfur cluster
                     binding"
                     /label="SCO0188"
                     /locus_tag="SCO0188"
                     /protein_end="130"
                     /protein_start="51"
                     /score="50.3"
                     /tool="antismash"
                     /translation="NWFVVGASRQVRAGDRPYGRTVGGVEVVLWRSDDGEPRAGSGICP
                     HLGAPLRDSRVVCGTLVCHWHGLALDGSASAGWR"
     PFAM_domain     11434..11991
                     /aSDomain="DUF5914"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF19299.2"
                     /description="Domain of unknown function (DUF5914)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0188_0061"
                     /evalue="6.80E-96"
                     /label="SCO0188"
                     /locus_tag="SCO0188"
                     /protein_end="333"
                     /protein_start="147"
                     /score="319.4"
                     /tool="antismash"
                     /translation="VGGEEPTERPVVPTRPATGRGVDSVFTATGRCEPQDVVANRLDPW
                     HGSWFHPYSFVDLSVVREPQGGEDDAFVVDVSFRVAGRLVVPVRAEFTAPEPRTVVMRI
                     TDGEGATSVVETHATPLTGPDHERPRTAVVEAVVAASDRPGFALARAAAPVLRPLMRRT
                     AGRLWRDDLAYAERRWALRSTGR"
     gene            complement(12019..13587)
                     /db_xref="GeneID:1095613"
                     /gene_synonym="crtU; SCJ1.38c"
                     /locus_tag="SCO0189"
     CDS             complement(12019..13587)
                     /codon_start=1
                     /db_xref="GeneID:1095613"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="crtU; SCJ1.38c"
                     /locus_tag="SCO0189"
                     /note="SCJ1.38c, crtU, probable dehydrogenase, a partial
                     CDS, len: >336 aa. Highly similar to Streptomyces griseus
                     TR:P72449 (EMBL:X95596) dehydrogenase (517 aa), fasta
                     scores opt: 1277 z-score: 1459.8 E():0 69.0% identity in
                     281 aa overlap and Synechocystis sp SW:CRTI_SYNY3 (EMBL;
                     X62574) phytoene dehydrogenase (427 aa), fasta scores opt:
                     133 z-score: 155.8 E():0.25 24.6% identity in 260 aa
                     overlap.; SCJ12.01c, crtU, probable dehydrogenase, partial
                     CDS, len: >278 aa. Highly similar to Streptomyces griseus
                     TR:P72449 (EMBL:X95596) dehydrogenase (517 aa), fasta
                     scores opt: 1311 z-score: 1471.3 E(): 0 74.0% identity in
                     269 aa overlap and Synechocystis sp. (strain PCC 6803)
                     SW:CRTI_SYNY3 (EMBL:X62574) phytoene dehydrogenase (EC
                     1.3.-.-) (phytoene desaturase) (427 aa), fasta scores opt:
                     219 z-score: 250.2 E(): 1.4e-06 27.6% identity in 254 aa
                     overlap."
                     /product="dehydrogenase"
                     /protein_id="NP_733493.1"
                     /sec_met_domain="DAO (E-value: 3.1e-12, bitscore: 45.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVRRTAAARRGRDRKAEIVFPAPGADRFGRGDEPSVAVIGGGIA
                     GLAAATLMAERGARVTLYEKEDAVGGRLSGRRTTLADGSAVTMTRGFHAFFRQYYNLRG
                     LLRRTDPGLDRLTPLPDYPLRHSGGLTDGFARVPRTPPLSAIGFVALSPTFGWRDLAAM
                     DPRAALPLLDVRVPQVYERFDGVTATAFLESVRFPEAAHHLAFEVFSRSFFADPRRLSA
                     AELLLMFHIYFLGSSEGLLFDVPVEPFPQALWNPLGDYLRRLGADVRTGTPVHGILPRA
                     DGGADVLTDTGADRHQAVVLALDTAGLRQTVAASPGLGTDTWRDGIAALRTAPPFLVSR
                     LWLDRPVDADRPGFLGTSGYGGLDNVSVLERYEGEAARWAARTGGSVVELHAYAVDPAA
                     EPKEVQDELVDRLHQAYPETREARVVDARHEWRADCPMFEVGSHRRRPTVRTPHPWLTL
                     AGDGIRCDLPVALMERAATTGFLAANALLADRGVRGQVLWTVPRTGRSPVLRAFGAVAG
                     HRSAP"
     PFAM_domain     complement(12127..13458)
                     /aSDomain="Amino_oxidase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01593.27"
                     /db_xref="GO:0016491"
                     /description="Flavin containing amine oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0189_0062"
                     /evalue="7.90E-33"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO0189"
                     /locus_tag="SCO0189"
                     /protein_end="487"
                     /protein_start="43"
                     /score="114.5"
                     /tool="antismash"
                     /translation="IAGLAAATLMAERGARVTLYEKEDAVGGRLSGRRTTLADGSAVTM
                     TRGFHAFFRQYYNLRGLLRRTDPGLDRLTPLPDYPLRHSGGLTDGFARVPRTPPLSAIG
                     FVALSPTFGWRDLAAMDPRAALPLLDVRVPQVYERFDGVTATAFLESVRFPEAAHHLAF
                     EVFSRSFFADPRRLSAAELLLMFHIYFLGSSEGLLFDVPVEPFPQALWNPLGDYLRRLG
                     ADVRTGTPVHGILPRADGGADVLTDTGADRHQAVVLALDTAGLRQTVAASPGLGTDTWR
                     DGIAALRTAPPFLVSRLWLDRPVDADRPGFLGTSGYGGLDNVSVLERYEGEAARWAART
                     GGSVVELHAYAVDPAAEPKEVQDELVDRLHQAYPETREARVVDARHEWRADCPMFEVGS
                     HRRRPTVRTPHPWLTLAGDGIRCDLPVALMERAATTGFLAANALL"
     misc_feature    12752..12884
                     /note="665 (-1) 36793 36925 overlap with cosmid StJ1"
     misc_feature    complement(12752..12884)
                     /gene_synonym="crtU; SCJ1.38c"
                     /locus_tag="SCO0189"
                     /note="overlap with StJ12"
     gene            complement(13584..14324)
                     /db_xref="GeneID:1095614"
                     /gene_synonym="crtT; SCJ12.02c"
                     /locus_tag="SCO0190"
     CDS             complement(13584..14324)
                     /codon_start=1
                     /db_xref="GeneID:1095614"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 76.7; E-value:
                     3.1e-23)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="crtT; SCJ12.02c"
                     /locus_tag="SCO0190"
                     /note="SCJ12.02c, crtT, probable methyltransferase, len:
                     246 aa. Shares a high level of sequence similarity with
                     Streptomyces griseus TR:P72450 (EMBL:X95596)
                     methyltransferase (242 aa), fasta scores opt: 984 z-score:
                     1164.2 E(): 0 65.0% identity in 234 aa overlap. Contains a
                     Pfam match to entry PF01209 Ubie_methyltran, ubiE/COQ5
                     methyltransferase family"
                     /product="methyltransferase"
                     /protein_id="NP_624525.1"
                     /transl_table=11
                     /translation="MTLLRDHDLARAFDHASHTYDGLTALNPGYRTGLLRSARRLALPA
                     DGAGLHLLDLGCGTGASTRALLRAAPRARITAVDASAGMLRRALVKPWPARVRFLHLTA
                     EEFATTREDEGPFDAVFAAYLFRNVTDPDAVLRAVRQLLRPGGRFAAHEYSLSGSPGHR
                     ALWSAVCRGVVIPAGTLTGDRTLYRHLRRSVVAFDTAPEFAARLTRAGLTSVRVAPVAG
                     WQTGIVHTFLARNGGPTTTEERVL"
     regulatory      complement(13596..13601)
                     /gene_synonym="crtT; SCJ12.02c"
                     /locus_tag="SCO0190"
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(13623..14324)
                     /gene_synonym="crtT; SCJ12.02c"
                     /locus_tag="SCO0190"
                     /note="Pfam match to entry PF01209 Ubie_methyltran,
                     ubiE/COQ5 methyltransferase family, score -45.20, E-value
                     1.1e-08"
     PFAM_domain     complement(13668..14309)
                     /aSDomain="Ubie_methyltran"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01209.21"
                     /description="ubiE/COQ5 methyltransferase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0190_0063"
                     /evalue="1.90E-19"
                     /label="SCO0190"
                     /locus_tag="SCO0190"
                     /protein_end="219"
                     /protein_start="5"
                     /score="70.1"
                     /tool="antismash"
                     /translation="DHDLARAFDHASHTYDGLTALNPGYRTGLLRSARRLALPADGAGL
                     HLLDLGCGTGASTRALLRAAPRARITAVDASAGMLRRALVKPWPARVRFLHLTAEEFAT
                     TREDEGPFDAVFAAYLFRNVTDPDAVLRAVRQLLRPGGRFAAHEYSLSGSPGHRALWSA
                     VCRGVVIPAGTLTGDRTLYRHLRRSVVAFDTAPEFAARLTRAGLTSVRVAP"
     gene            complement(14321..15538)
                     /db_xref="GeneID:1095615"
                     /gene_synonym="crtY; SCJ12.03c"
                     /locus_tag="SCO0191"
     CDS             complement(14321..15538)
                     /codon_start=1
                     /db_xref="GeneID:1095615"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /gene_synonym="crtY; SCJ12.03c"
                     /locus_tag="SCO0191"
                     /note="SCJ12.03c, crtY, probable lycopene cyclase, len: 405
                     aa. Highly similar to Streptomyces griseus TR:P72451
                     (EMBL:X95596) lycopene cyclase (418 aa), fasta scores opt:
                     1426 z-score: 1602.7 E(): 0 56.3% identity in 396 aa
                     overlap"
                     /product="lycopene cyclase"
                     /protein_id="NP_624526.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 3.1e-111,
                     bitscore: 370.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPRSAQDSDVLVIGGGAAGLSLAHRLTENGTAPAMTLVEPPDGP
                     LRPAERTWCYWGAAADGLEEAVGASWSVLRLHGADGGSVTVDPAPFTYRMVRSADFERM
                     VHGRLARTDGARLLRGTAESVRAVPAGTEVRCTLPGGRPLTLYARRVFDSRPLPELPPA
                     RTCLLQHFRGWFVHTRTDRFDPAVADLMDFRVPQPAHGLAFGYVLPLAPDRALVEYTEF
                     SRAPLTTEAYESALGHYCRDILGLGELTVERTEQGVIPMTDARFPGRAGPAVYRIGTAG
                     GATRPATGYTFAAVQRHSGAIAAALRDGHDRVPAPHGRRARAMDAVLLRALDTGRIDGP
                     RFFTDLFRRVPAERLLRFLDGTTSLREEWGIGLRTPVRPMLRTAAEVPFLPRRSQPLAR
                     TGGNNR"
     PFAM_domain     complement(14387..15511)
                     /aSDomain="Lycopene_cycl"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05834.15"
                     /description="Lycopene cyclase protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0191_0064"
                     /evalue="5.20E-130"
                     /label="SCO0191"
                     /locus_tag="SCO0191"
                     /protein_end="384"
                     /protein_start="9"
                     /score="434.0"
                     /tool="antismash"
                     /translation="DVLVIGGGAAGLSLAHRLTENGTAPAMTLVEPPDGPLRPAERTWC
                     YWGAAADGLEEAVGASWSVLRLHGADGGSVTVDPAPFTYRMVRSADFERMVHGRLARTD
                     GARLLRGTAESVRAVPAGTEVRCTLPGGRPLTLYARRVFDSRPLPELPPARTCLLQHFR
                     GWFVHTRTDRFDPAVADLMDFRVPQPAHGLAFGYVLPLAPDRALVEYTEFSRAPLTTEA
                     YESALGHYCRDILGLGELTVERTEQGVIPMTDARFPGRAGPAVYRIGTAGGATRPATGY
                     TFAAVQRHSGAIAAALRDGHDRVPAPHGRRARAMDAVLLRALDTGRIDGPRFFTDLFRR
                     VPAERLLRFLDGTTSLREEWGIGLRTPVRPMLRTA"
     gene            complement(15809..17059)
                     /db_xref="GeneID:1095616"
                     /gene_synonym="SCJ12.04c"
                     /locus_tag="SCO0192"
     CDS             complement(15809..17059)
                     /codon_start=1
                     /db_xref="GeneID:1095616"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 64.3; E-value: 1.9e-19)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCJ12.04c"
                     /locus_tag="SCO0192"
                     /note="SCJ12.04c, possible oxidoreductase, len: 416 aa.
                     Similar to many protoporphyrinogen oxidases including:
                     Propionibacterium freudenreichii shermanii SW:PPOX_PROFR
                     (EMBL:D85417) HemY (527 aa), fasta scores opt: 228 z-score:
                     249.0 E(): 1.6e-06 26.8% identity in 504 aa overlap and
                     Bacillus subtilis SW:PPOX_BACSU (EMBL; M97208) HemY (470
                     aa), fasta scores opt: 209 z-score: 229.3 E(): 2.1e-05
                     25.7% identity in 311 aa overlap. Contains a Pfam match to
                     entry PF01593 Amino_oxidase"
                     /product="oxidoreductase"
                     /protein_id="NP_624527.1"
                     /sec_met_domain="DAO (E-value: 4.4e-09, bitscore: 35.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDGQHRAADAVVVGAGLAGLACALDLCRAGWRVALLEASDGVGG
                     RMRTDRRDGFLLDRGFQVFNTSYPQVKRRMELKSLRLRPFTAGVVAHTSNGPVRLADPT
                     REPRAAGTLLPGRALPARDLAALAALTARDAVLPVAVTRRRRDRPTSAALSRVGLSDAA
                     IAGILRPFLSGVFLEDRLETSARFFHLVWRSMVRGSLCLPAEGIGAVPAQLADGLPDGV
                     LRLGTPVAEITDAGVLLGDGGEVPARVVVVATDPATAAGLLPDLTVPDTRTVTTYYHAT
                     DSPPTAEPILMVDSTGAILNTCVLSQVAPTYAPPGTGLVSTSVLGTDPPGRAQAVLRRL
                     AELYGTDTSGWEQVAARTVDGALPAMLPPWPLSRTTRIGPGRYVCGDHRATGSVQGALA
                     SGTRAAREVRADREPQR"
     misc_feature    complement(15833..17008)
                     /gene_synonym="SCJ12.04c"
                     /locus_tag="SCO0192"
                     /note="Pfam match to entry PF01593 Amino_oxidase, score
                     -105.60, E-value 0.0012"
     PFAM_domain     complement(15836..17008)
                     /aSDomain="Amino_oxidase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01593.27"
                     /db_xref="GO:0016491"
                     /description="Flavin containing amine oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0192_0065"
                     /evalue="2.40E-50"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="SCO0192"
                     /locus_tag="SCO0192"
                     /protein_end="408"
                     /protein_start="17"
                     /score="172.3"
                     /tool="antismash"
                     /translation="LAGLACALDLCRAGWRVALLEASDGVGGRMRTDRRDGFLLDRGFQ
                     VFNTSYPQVKRRMELKSLRLRPFTAGVVAHTSNGPVRLADPTREPRAAGTLLPGRALPA
                     RDLAALAALTARDAVLPVAVTRRRRDRPTSAALSRVGLSDAAIAGILRPFLSGVFLEDR
                     LETSARFFHLVWRSMVRGSLCLPAEGIGAVPAQLADGLPDGVLRLGTPVAEITDAGVLL
                     GDGGEVPARVVVVATDPATAAGLLPDLTVPDTRTVTTYYHATDSPPTAEPILMVDSTGA
                     ILNTCVLSQVAPTYAPPGTGLVSTSVLGTDPPGRAQAVLRRLAELYGTDTSGWEQVAAR
                     TVDGALPAMLPPWPLSRTTRIGPGRYVCGDHRATGSVQGALASGTRAAREV"
     regulatory      complement(17064..17068)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(17293..18297)
                     /db_xref="GeneID:1095617"
                     /gene_synonym="SCJ12.05c"
                     /locus_tag="SCO0193"
     CDS             complement(17293..18297)
                     /codon_start=1
                     /db_xref="GeneID:1095617"
                     /gene_synonym="SCJ12.05c"
                     /locus_tag="SCO0193"
                     /note="SCJ12.05c, possible DNA-binding regulator, len:334
                     aa. Some similarity to Myxococcus xanthus TR:Q50900
                     (EMBL:Z21955) regulatory protein (299 aa), fasta scores
                     opt: 121 z-score: 141.6 E(): 1.6 32.4% identity in 281 aa
                     overlap and Myxococcus xanthus TR:Q50899 (EMBL:Z21955)
                     regulatory protein (288 aa), fasta scores opt: 118 z-score:
                     138.5 E() 2.4 26.9% identity in 279 aa overlap. Contains a
                     possible helix-turn-helix motif between aa's 23..44."
                     /product="DNA-binding regulator"
                     /protein_id="NP_624528.1"
                     /transl_table=11
                     /translation="MNAYTGDGDEPVDDGGPRRGGLTTGEVARRLGVAPTTVRTWDRRY
                     GLGPDAHVDGRHRRWTAADLARLERMCALTATGLPPAEAARLARSEERPTAAGPRNTDA
                     ARRAPTGRRSRAGSGLQLGDVRQECRGIARAALRLDASALDELLLAAIAEHGLVAAWTE
                     VIVPTLQAVGRKWETSGEKYVEVEHFLSWHVSGALRRAAPPAVEDRPGSTTVLACVPGE
                     NHTLPLEVLSAALTERGVPVRMFGGALPVESLVAAVRRTGPAAVGLWSQSRTTASRPLA
                     QHVAAMEWGVRGARRRPVVLTLGPGWAGQAVAGLARPSGLAEAVAALEPSVYP"
     PFAM_domain     complement(17698..17910)
                     /aSDomain="B12-binding_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02607.20"
                     /description="B12 binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0193_0067"
                     /evalue="1.10E-07"
                     /label="SCO0193"
                     /locus_tag="SCO0193"
                     /protein_end="200"
                     /protein_start="129"
                     /score="32.4"
                     /tool="antismash"
                     /translation="RGIARAALRLDASALDELLLAAIAEHGLVAAWTEVIVPTLQAVGR
                     KWETSGEKYVEVEHFLSWHVSGALRR"
     PFAM_domain     complement(18028..18231)
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13411.9"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0006355"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0193_0066"
                     /evalue="1.90E-12"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO0193"
                     /locus_tag="SCO0193"
                     /protein_end="90"
                     /protein_start="22"
                     /score="47.1"
                     /tool="antismash"
                     /translation="TTGEVARRLGVAPTTVRTWDRRYGLGPDAHVDGRHRRWTAADLAR
                     LERMCALTATGLPPAEAARLARS"
     regulatory      18445..18450
                     /regulatory_class="ribosome_binding_site"
     gene            18458..19066
                     /db_xref="GeneID:1095618"
                     /gene_synonym="SCJ12.06"
                     /locus_tag="SCO0194"
     CDS             18458..19066
                     /codon_start=1
                     /db_xref="GeneID:1095618"
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 131.9;
                     E-value: 3.1e-40)"
                     /gene_kind="regulatory"
                     /gene_synonym="SCJ12.06"
                     /locus_tag="SCO0194"
                     /note="SCJ12.06, possible sigma factor, len: 202 aa.
                     Similar to many including: Rhodobacter sphaeroide TR:O33546
                     (EMBL; U11283) RpoE homologue (168 aa), fasta scores opt:
                     291 z-score: 373.4 E(): 1.9e-13 35.4% identity in 161 aa
                     overlap and Streptomyces coelicolor TR:O54163 (EMBL;
                     AL021411) sigma factor SC7H1.04 (200 aa), fasta scores opt:
                     255 z-score: 327.4 E(): 7.1e-11 33.7% identity in 184 aa
                     overlap. Contains a PS01063 Sigma-70 factors ECF subfamily
                     signature and a Pfam match to entry PF00776 Sigma70_ECF,
                     Sigma-70 factor (ECF subfamily). Contains a possible
                     helix-turn-helix motif between aa's 162..183."
                     /product="sigma factor"
                     /protein_id="NP_624529.1"
                     /transl_table=11
                     /translation="MNTRTRPTTTPVPPVEETRYEEELAHGLVKADEDAFAAIYRRWGS
                     LVHTLATRSLGDAHEAEDVTQQVFVGAWRGRHGFRPERGTLGAWLVGITRRKVVDALAA
                     RTRRLSLVESAGQDITPARLVQPALDEVLDRVLLVEALSRLPQAQRDVLCMAFYEDLTQ
                     AQIAERTGVPLGTVKSHARRGLHRLRTAVGPGAAHDTCV"
     aSDomain        18557..19030
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_SCO0194_0004"
                     /evalue="5.20E-25"
                     /identifier="TIGR02937"
                     /label="SCO0194"
                     /locus_tag="SCO0194"
                     /protein_end="191"
                     /protein_start="33"
                     /score="85.9"
                     /tool="antismash"
                     /translation="DAFAAIYRRWGSLVHTLATRSLGDAHEAEDVTQQVFVGAWRGRHG
                     FRPERGTLGAWLVGITRRKVVDALAARTRRLSLVESAGQDITPARLVQPALDEVLDRVL
                     LVEALSRLPQAQRDVLCMAFYEDLTQAQIAERTGVPLGTVKSHARRGLHRLRTA"
     PFAM_domain     18572..18778
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04542.17"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006352"
                     /db_xref="GO:0006355"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0194_0068"
                     /evalue="5.00E-18"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006352: DNA-templated transcription
                     initiation"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO0194"
                     /locus_tag="SCO0194"
                     /protein_end="107"
                     /protein_start="38"
                     /score="64.8"
                     /tool="antismash"
                     /translation="IYRRWGSLVHTLATRSLGDAHEAEDVTQQVFVGAWRGRHGFRPER
                     GTLGAWLVGITRRKVVDALAARTR"
     misc_feature    18602..18808
                     /gene_synonym="SCJ12.06"
                     /locus_tag="SCO0194"
                     /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70
                     factor (ECF subfamily), score 47.10, E-value 3.8e-10"
     misc_feature    18638..18736
                     /gene_synonym="SCJ12.06"
                     /locus_tag="SCO0194"
                     /note="PS01063 Sigma-70 factors ECF subfamily signature,
                     info count = 32.1"
     PFAM_domain     18878..19024
                     /aSDomain="Sigma70_r4"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF04545.19"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006352"
                     /db_xref="GO:0006355"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0194_0069"
                     /evalue="4.70E-17"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006352: DNA-templated transcription
                     initiation"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /label="SCO0194"
                     /locus_tag="SCO0194"
                     /protein_end="189"
                     /protein_start="140"
                     /score="61.4"
                     /tool="antismash"
                     /translation="ALSRLPQAQRDVLCMAFYEDLTQAQIAERTGVPLGTVKSHARRGL
                     HRLR"
     regulatory      19160..19164
                     /regulatory_class="ribosome_binding_site"
     gene            19175..19861
                     /db_xref="GeneID:1095619"
                     /gene_synonym="SCJ12.07"
                     /locus_tag="SCO0195"
     CDS             19175..19861
                     /codon_start=1
                     /db_xref="GeneID:1095619"
                     /gene_synonym="SCJ12.07"
                     /locus_tag="SCO0195"
                     /note="SCJ12.07, possible lipoprotein, len: 228 aa.
                     Contains an N-terminal signal sequence and a PS00013
                     Prokaryotic membrane lipoprotein lipid attachment site."
                     /product="lipoprotein"
                     /protein_id="NP_624530.1"
                     /transl_table=11
                     /translation="MMSRTTIAVAGSAGACALAPTAPAATAAPEQAQDTGLVSVFHGIP
                     GTTVDVFANGDEPLGDFQPGTVTEGGNTTVAAHLSADGKPRLTTFTDDVSKTDAGRSRL
                     TVRHVAAAPAVDVRAGGHPLFTGLANPDEDTALVEAGIVNADVVLAGTETVVVGPAGLD
                     LKEGTTNVVYAWGSAEDQTLALPGQAFGGMDSTPLAVHPGAGGTAATPNASDRWRARAA
                     TPARSR"
     misc_feature    19190..19222
                     /gene_synonym="SCJ12.07"
                     /locus_tag="SCO0195"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site."
     PFAM_domain     19370..19525
                     /aSDomain="DUF4397"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF14344.9"
                     /description="Domain of unknown function (DUF4397)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0195_0070"
                     /evalue="4.60E-08"
                     /label="SCO0195"
                     /locus_tag="SCO0195"
                     /protein_end="117"
                     /protein_start="65"
                     /score="33.9"
                     /tool="antismash"
                     /translation="TVTEGGNTTVAAHLSADGKPRLTTFTDDVSKTDAGRSRLTVRHVA
                     AAPAVDV"
     regulatory      19972..19977
                     /regulatory_class="ribosome_binding_site"
     gene            19983..20387
                     /db_xref="GeneID:1095620"
                     /gene_synonym="SCJ12.08"
                     /locus_tag="SCO0196"
     CDS             19983..20387
                     /codon_start=1
                     /db_xref="GeneID:1095620"
                     /gene_synonym="SCJ12.08"
                     /locus_tag="SCO0196"
                     /note="SCJ12.08, unknown, len:134 aa. Shares a low level of
                     similarity with Mycobacterium tuberculosis TR:O53597 (EMBL;
                     AL021426) hypothetical 24.0 KD protein MTV028.10C (224 aa),
                     fasta scores opt: 119 z-score: 159.2 E(): 0.1 32.8%
                     identity in 116 aa overlap."
                     /product="hypothetical protein"
                     /protein_id="NP_624531.1"
                     /transl_table=11
                     /translation="MGHVHPSHLVELALGHASGEADVGALRHAASCPRCREELLRLTRV
                     VTAARGAEASDLPVPPPERVWQRIALEVLPETDRVPRLRESSAHGSADERVRGSQRRWT
                     DHAGEGLLGLALAIAVLLLRRWRIRAGSGN"
     gene            complement(20519..20959)
                     /db_xref="GeneID:1095621"
                     /gene_synonym="SCJ12.09c"
                     /locus_tag="SCO0197"
     CDS             complement(20519..20959)
                     /codon_start=1
                     /db_xref="GeneID:1095621"
                     /gene_synonym="SCJ12.09c"
                     /locus_tag="SCO0197"
                     /note="SCJ12.09c, hypothetical protein, len: 146 aa. Some
                     similarity to Mycobacterium tuberculosis TR:O53625 (EMBL;
                     AL021428) hypothetical 16.6 KD protein (152 aa), fasta
                     scores opt: 291 z-score: 377.8 E(): 1.1e-13 42.9% identity
                     in 133 aa overlap. Also similar to TR:Q9RI34
                     (EMBL:AL109989) S. coelicolor SCJ12.26 (137 aa), fasta
                     scores: opt: 524 z-score: 568.0 E(): 2.2e-26 62.2% identity
                     in 135 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_624532.1"
                     /transl_table=11
                     /translation="MYRNDGFRELNRQESLQRLANAPVGRIVHTRDALPAVLPVNFVLE
                     KSGAVLLRTSASSELVRAVDGAVVAFEADEVDAVTHSGWSVVVTGLASVVTDPGEHEQL
                     VRTGPRSWVPWPVEVFVRIAPDLVSGRELVGGRTLYGLDPPT"
     PFAM_domain     complement(20567..20926)
                     /aSDomain="Pyridox_ox_2"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF12900.10"
                     /description="Pyridoxamine 5'-phosphate oxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0197_0071"
                     /evalue="8.90E-26"
                     /label="SCO0197"
                     /locus_tag="SCO0197"
                     /protein_end="131"
                     /protein_start="11"
                     /score="90.7"
                     /tool="antismash"
                     /translation="RQESLQRLANAPVGRIVHTRDALPAVLPVNFVLEKSGAVLLRTSA
                     SSELVRAVDGAVVAFEADEVDAVTHSGWSVVVTGLASVVTDPGEHEQLVRTGPRSWVPW
                     PVEVFVRIAPDLVSGR"
     gene            complement(21492..22358)
                     /db_xref="GeneID:1095622"
                     /gene_synonym="SCJ12.10c"
                     /locus_tag="SCO0198"
     CDS             complement(21492..22358)
                     /codon_start=1
                     /db_xref="GeneID:1095622"
                     /gene_synonym="SCJ12.10c"
                     /locus_tag="SCO0198"
                     /note="SCJ12.10c, unknown, len: 288 aa. Similar to several
                     hypothetical proteins including: Mycobacterium tuberculosis
                     SW:YW12_MYCTU (EMBL; Z74025) hypothetical 30.9 KD protein
                     MTCY39.12 (295 aa), fasta scores opt: 363 z-score: 441.0
                     E(): 3.3e-17 32.3% identity in 288 aa overlap and
                     Mycobacterium tuberculosis TR:O06189 (EMBL; Z95387)
                     hypothetical 31.7 KD protein MTCY1A10.09C (297 aa), fasta
                     scores opt: 336 z-score: 408.6 E(): 2.1e-15 29.3% identity
                     in 294 aa overlap. Also highly similar to S. coelicolor
                     hypothetical proteins (AL109962) SCJ1.29c (283 aa), fasta
                     scores opt: 1161 z-score: 1097.2 E(): 0 63.5% identity in
                     288 aa overlap and SCJ1.16c (294 aa), fasta scores opt:892
                     z-score: 844.7 E():0 50.3% identity in 296 aa overlap"
                     /product="hypothetical protein"
                     /protein_id="NP_624533.1"
                     /transl_table=11
                     /translation="MYLPMVVGVDGSESSLGAVDWAADEAALHEVPLRIVHAYRWDRYE
                     GASLARELGKPSGHVTTDDILAVATRRARRHHPDLAVTTEATAEEPEYVLLREARNASA
                     VILGTRGRGELAGLLLGSVSLTVATMSDCPVVVTRGDHDDRAAGGGRRGRIVVGVADAP
                     TAAVRFACEEARRRGAALDAVRAWRCPTHDTVDHPLLAGTPERLHEERAAKELEAALAD
                     APADVRLRRRTAEGPGSRVLSAASHEADLLVVGRRRPGQFGHRLGRVAHTLLHHSACPV
                     AVVPDTT"
     PFAM_domain     complement(21504..21899)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0198_0073"
                     /evalue="1.40E-19"
                     /label="SCO0198"
                     /locus_tag="SCO0198"
                     /protein_end="285"
                     /protein_start="153"
                     /score="71.1"
                     /tool="antismash"
                     /translation="RIVVGVADAPTAAVRFACEEARRRGAALDAVRAWRCPTHDTVDHP
                     LLAGTPERLHEERAAKELEAALADAPADVRLRRRTAEGPGSRVLSAASHEADLLVVGRR
                     RPGQFGHRLGRVAHTLLHHSACPVAVVP"
     PFAM_domain     complement(21942..22358)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0198_0072"
                     /evalue="6.10E-25"
                     /label="SCO0198"
                     /locus_tag="SCO0198"
                     /protein_end="139"
                     /protein_start="0"
                     /score="88.5"
                     /tool="antismash"
                     /translation="MYLPMVVGVDGSESSLGAVDWAADEAALHEVPLRIVHAYRWDRYE
                     GASLARELGKPSGHVTTDDILAVATRRARRHHPDLAVTTEATAEEPEYVLLREARNASA
                     VILGTRGRGELAGLLLGSVSLTVATMSDCPVVVTR"
     gene            complement(22364..23386)
                     /db_xref="GeneID:1095623"
                     /gene_synonym="SCJ12.11c"
                     /locus_tag="SCO0199"
     CDS             complement(22364..23386)
                     /NRPS_PKS="Domain: PKS_ER (15-227). E-value: 3.6e-12.
                     Score: 37.9. Matches aSDomain:
                     nrpspksdomains_SCO0199_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:1095623"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 306.2; E-value:
                     4.2e-93)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="SCJ12.11c"
                     /locus_tag="SCO0199"
                     /note="SCJ12.11c, probable alcohol dehydrogenase, len: 340
                     aa. Highly similar to many e.g. Bacillus stearothermophilus
                     SW:ADH3_BACST (EMBL; Z27089) alcohol dehydrogenase (EC
                     1.1.1.1) (ADH-HT) (339 aa), fasta scores opt: 1281 z-score:
                     1383.7 E(): 0 55.2% identity in 337 aa overlap. Contains a
                     PS00059 Zinc-containing alcohol dehydrogenases signature
                     and a Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases."
                     /product="alcohol dehydrogenase"
                     /protein_id="NP_624534.1"
                     /sec_met_domain="ADH_N (E-value: 1.9e-31, bitscore: 107.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.5e-28, bitscore:
                     96.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAAVVREFGKPLVIEDRPDPEPGPGQVLVAVEASGLCHTDIHAA
                     HGDWPVKPTPPFVPGHEGVGLVEKLGDGVTHLAVGQRVAVPWLGKACGRCEHCRSGWET
                     LCEDQVNTGYGCDGGYAEKMLAWADFAQPVPEGVSALDAAPLTCAGVTTYKALKVAEVG
                     PAQLVAVSGVGGLGHLAVQYAKIAGARVVAIDVTDDKLQLARELGADLVIDARTQDVGA
                     ELKRHGGAHAALALAVNPAAFQAVNSGLRRGGKLVMVALPAHGTLQVPIFDTVLNGTSV
                     IGSIVGTRQDLAEVFQLHAEGRTKVIRETRPLAAVNDCIDEVLGGQVKARIVFDLNAGG
                     "
     regulatory      complement(22368..22372)
                     /gene_synonym="SCJ12.11c"
                     /locus_tag="SCO0199"
                     /regulatory_class="ribosome_binding_site"
     misc_feature    complement(22382..23380)
                     /gene_synonym="SCJ12.11c"
                     /locus_tag="SCO0199"
                     /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding
                     dehydrogenases, score 359.60, E-value 3.2e-104"
     PFAM_domain     complement(22493..22864)
                     /aSDomain="ADH_zinc_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00107.29"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0199_0075"
                     /evalue="1.60E-27"
                     /label="SCO0199"
                     /locus_tag="SCO0199"
                     /protein_end="298"
                     /protein_start="174"
                     /score="96.2"
                     /tool="antismash"
                     /translation="GLGHLAVQYAKIAGARVVAIDVTDDKLQLARELGADLVIDARTQD
                     VGAELKRHGGAHAALALAVNPAAFQAVNSGLRRGGKLVMVALPAHGTLQVPIFDTVLNG
                     TSVIGSIVGTRQDLAEVFQL"
     aSDomain        complement(22706..23341)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCO0199_PKS_ER.1"
                     /evalue="3.60E-12"
                     /label="SCO0199_PKS_ER.1"
                     /locus_tag="SCO0199"
                     /protein_end="227"
                     /protein_start="15"
                     /score="37.9"
                     /tool="antismash"
                     /translation="EDRPDPEPGPGQVLVAVEASGLCHTDIHAAHGDWPVKPTPPFVPG
                     HEGVGLVEKLGDGVTHLAVGQRVAVPWLGKACGRCEHCRSGWETLCEDQVNTGYGCDGG
                     YAEKMLAWADFAQPVPEGVSALDAAPLTCAGVTTYKALKVAEVGPAQLVAVSGVGGLGH
                     LAVQYAKIAGARVVAIDVTDDKLQLARELGADLVIDARTQDVGAELKRH"
     PFAM_domain     complement(23003..23314)
                     /aSDomain="ADH_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08240.15"
                     /description="Alcohol dehydrogenase GroES-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0199_0074"
                     /evalue="4.70E-31"
                     /label="SCO0199"
                     /locus_tag="SCO0199"
                     /protein_end="128"
                     /protein_start="24"
                     /score="107.0"
                     /tool="antismash"
                     /translation="PGQVLVAVEASGLCHTDIHAAHGDWPVKPTPPFVPGHEGVGLVEK
                     LGDGVTHLAVGQRVAVPWLGKACGRCEHCRSGWETLCEDQVNTGYGCDGGYAEKMLAWA
                     "
     misc_feature    complement(23165..23209)
                     /gene_synonym="SCJ12.11c"
                     /locus_tag="SCO0199"
                     /note="PS00059 Zinc-containing alcohol dehydrogenases
                     signature."
     regulatory      complement(23394..23399)
                     /regulatory_class="ribosome_binding_site"
     gene            complement(23425..24330)
                     /db_xref="GeneID:1095624"
                     /gene_synonym="SCJ12.12c"
                     /locus_tag="SCO0200"
     CDS             complement(23425..24330)
                     /codon_start=1
                     /db_xref="GeneID:1095624"
                     /gene_synonym="SCJ12.12c"
                     /locus_tag="SCO0200"
                     /note="SCJ12.12c, unknown, len: 301 aa. Similar to several
                     hypothetical proteins including: Mycobacterium tuberculosis
                     SW:YW23_MYCTU (EMBL; Z74025) hypothetical 33.9 KD protein
                     MTCY39.23C (317 aa), fasta scores opt: 380 z-score: 447.3
                     E(): 1.5e-17 33.5% identity in 316 aa overlap and S.
                     coelicolor (EMBL;AL109962) SCJ1.30c (328 aa)fasta scores
                     opt: 1274 z-score: 1163.7 E():0 65.3% identity in 300 aa
                     overlap. Contains 2x Pfam match to entry PF00582 Usp,
                     Universal stress protein family."
                     /product="hypothetical protein"
                     /protein_id="NP_624535.1"
                     /transl_table=11
                     /translation="MARTITVGLDGSPESRAAAEWAAREGTLRRVPVRLLHVWQPVPEP
                     MAQAPLLGAETHQHWTERIPRDTAEGLRLRHPGVEVTTEQATGNPADALLAGTLDAELL
                     VLGSRALSGLTGFLVGSVGQSVIARTETPVILVRAGEQAADEHLKDPTGIPSAATGFRP
                     VVVGLDTGSPDEAVLSFAFEEARRRRAPLTAVRAWNLPSSYTYSIAAGFDPREELARAQ
                     AEALGEALLPWREKYPDVEVTETCRLGSPAEHLIDAARDASLVVVGRRIRRSPFGVHIG
                     AVAHAVMHHATTPVAVVAHD"
     misc_feature    complement(23437..23754)
                     /gene_synonym="SCJ12.12c"
                     /locus_tag="SCO0200"
                     /note="Pfam match to entry PF00582 Usp, Universal stress
                     protein family, score 47.30, E-value 3.4e-10"
     PFAM_domain     complement(23437..23850)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0200_0077"
                     /evalue="1.70E-19"
                     /label="SCO0200"
                     /locus_tag="SCO0200"
                     /protein_end="298"
                     /protein_start="160"
                     /score="70.9"
                     /tool="antismash"
                     /translation="FRPVVVGLDTGSPDEAVLSFAFEEARRRRAPLTAVRAWNLPSSYT
                     YSIAAGFDPREELARAQAEALGEALLPWREKYPDVEVTETCRLGSPAEHLIDAARDASL
                     VVVGRRIRRSPFGVHIGAVAHAVMHHATTPVAVV"
     PFAM_domain     complement(23917..24330)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00582.29"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0200_0076"
                     /evalue="1.60E-25"
                     /label="SCO0200"
                     /locus_tag="SCO0200"
                     /protein_end="138"
                     /protein_start="0"
                     /score="90.4"
                     /tool="antismash"
                     /translation="MARTITVGLDGSPESRAAAEWAAREGTLRRVPVRLLHVWQPVPEP
                     MAQAPLLGAETHQHWTERIPRDTAEGLRLRHPGVEVTTEQATGNPADALLAGTLDAELL
                     VLGSRALSGLTGFLVGSVGQSVIARTETPVILVR"
     misc_feature    complement(23920..24231)
                     /gene_synonym="SCJ12.12c"
                     /locus_tag="SCO0200"
                     /note="Pfam match to entry PF00582 Usp, Universal stress
                     protein family, score 27.00, E-value 0.00011"
     misc_feature    24415..24429
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: strong, score: 28.31"
                     /tool="antismash"
     gene            complement(24483..25154)
                     /db_xref="GeneID:1095625"
                     /gene_synonym="SCJ12.13c"
                     /locus_tag="SCO0201"
     CDS             complement(24483..25154)
                     /codon_start=1
                     /db_xref="GeneID:1095625"
                     /gene_synonym="SCJ12.13c"
                     /locus_tag="SCO0201"
                     /note="SCJ12.13c, possible integral membrane protein, len:
                     223 aa. Contains potential membrane spanning hydrophobic
                     domains."
                     /product="hypothetical protein"
                     /protein_id="NP_624536.1"
                     /transl_table=11
                     /translation="MSGTNRILSEGVTVMAMHQSTHRGSGFHLPSSRRNGAVSVPGAAD
                     SVEAGALTARAFVFASARVLMGFVFLWAFLDKTFGFGYATASGKGWIDGGSPTEGFLGH
                     VAVGPMESTFHSWAGAAWADWLFMLGLLGVGLALTAGVALRPAAVAGTVMMALMWAAEW
                     PPAKHLSDGSASMSTNPFADYHVLYAVLLIALAAVSAGDALGLGRLWARLPIVRDHAWL
                     R"
     PFAM_domain     complement(24675..24971)
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07681.15"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_SCO0201_0078"
                     /evalue="4.70E-05"
                     /label="SCO0201"
                     /locus_tag="SCO0201"
                     /protein_end="160"
                     /protein_start="61"
                     /score="24.0"
                     /tool="antismash"
                     /translation="ARVLMGFVFLWAFLDKTFGFGYATASGKGWIDGGSPTEGFLGHVA
                     VGPMESTFHSWAGAAWADWLFMLGLLGVGLALTAGVALRPAAVAGTVMMALMWA"
ORIGIN
        1 gcggcggccg ccggctacta cggcgcgcga gtcgtcctca accggcgtcg tcgcgccgcg
       61 tgggagcacg agtggcagga catcggttcc cagtggggac gcgcggccag ttgatccggg
      121 acacgtcgta gggcttccac cggcgcgaca tggaacggtt ctcgggtggt gaggaagccc
      181 gtgagggggg aggaggagcg atgagcgact tcatggtcgt ggcgcggacg gttccgcgcc
      241 gggtctccaa gccgtcgtac gggcggcgcg tgaggcagaa gtccgcaaca tgacgcttcg
      301 ggtcgtccac gcgctggccc ggcccgcgcc cgcaccgagg ccccgggtac cgttgtcgcg
      361 gggctggtct ttcccggaga accgcttccg atgctggtgg cgcaggctct gtccgccgct
      421 gcggtcgtgg tgggtcacag gggtccccat cccttccagg gagctctgat cggatccctc
      481 gcgaccgggc tcgccgccca ctccgagtgc cccgtggtgg tcgtaggcga gcccgagaat
      541 ccggcgggtc ctgtggcctt gggagtcgac ggatcggccg ccggagcggc tgccgtccgc
      601 cttccgggag acttccgtgc agggtgcgga catcaccgcc gtgcacgcct ggacggcctg
      661 gaacgcgccg atgccgcctc ccccagacga gagaccgagc cctacgcctg tgaacccggc
      721 atgctcgccg cggaggaagg gcggctgctg gccgagacgc tcgcgggcat gtgcgcccgc
      781 tatcccgagg tgagggtgga acgcagcacc gtccacggag tgcacggccg acgttgatcg
      841 aggaaggggg cacgatcacg acggaagtcg ctcaaggctt tcctgccggc ccagcgtccg
      901 gcgacccggc ccggcggact cgacgcccac cgggccggcc gtgtcacaca gcgtttgcgg
      961 cgacgacttc gcgcttcggg ccgccgagga ccaccttgag cgctccggtg tcggctgccg
     1021 cggagaagac ctcgtacgcc tcctccatgc gctccagcgg gaacgtgtgg gtcaccaact
     1081 ggccggtggg gagtcggccg gacgccgcca tgcgcaacag cgtcggcgtg gaacgggtgt
     1141 cgaccagacc ggtggtgacg gtgacgttct tgctccacag gtcttccagg tgcagggtcg
     1201 ccggcctgcc gtgcacgccg acgttggcga cgtgcccgcc cgggcgcacc acgcgcgtgc
     1261 acatctcgaa cgtctcgggg acgcccacgg cctcgatgac cacatcggcg ccgaggcccc
     1321 cggtgaggtc ggcgaccagt tgctccgggt cctcgcgggc gtccgccacg gcctcggccc
     1381 cgagcttccg ggcggcctcc agccgagcgg tggccagatc cacgacgacg atccgttcgg
     1441 gtgcgaacag ccgtgccgtg gcgaccgcgg cgagtcctat ggggccggcg cccaccacga
     1501 cgaccgtgtc tccggggctg acgcgtccgt tgagcacgcc cacctcgtag gccgtcggga
     1561 agatgtcggc gagcagcacg gcgtcctcgt cggtcaccgc gcccggcagg gagtgcacgg
     1621 agaggtccgc gtacgggact cgcacgtact cggcctgagt gccgttgatc aggtggccga
     1681 ggatccagcc ccctccgccg aggcactggc cgtacacgcc ctcacggcag taacggcacc
     1741 ttccgcaggc ggtgatgcag gacaccagga cgcggtctcc cggccgcacg gtgcgtacgt
     1801 ccgtgcccac ctcgacgatc tcgccgaccg cctcgtggcc gaggacggtt ccgggccgca
     1861 cctcggggac gtcccccttc aggatgtgca ggtccgtccc gcagatggtg acggcgtcga
     1921 cccgcacgat ggcgtcggtg ggctccttga gttccggatc cggtatgtcc tcccacgcgg
     1981 accggcccgg accgtggaat acgtagcctt tcatcgtgat gctcactctc cttgtgctcg
     2041 ggagcatccg gggccacggt gaccggaccg cgccgggcgg gcccacgacc gtcggtacga
     2101 cggggattgc cccacacctc cagactgtcc ccggcagcac gaacccgctt gggccggtcg
     2161 gccccccgcc cgccgcctgc cggccccggg tctgttcggt gtgctcacgt ccgctccggc
     2221 acgacgacga ccgggcaggc cgagcggtgc aggacggcgt gggcgacccg gccgagccgc
     2281 ccttgggtgc ggcggccgat caccagcagg ccggcttccg ccgaagcggc gggcagcacc
     2341 gcgcgtgccg ggccctcgac ggtgtaccga cgcacggcga cgtcgggcgg tgcgtcttcc
     2401 agggctgctt ccagttccct ggctgcccgc tcctcgtacc gccgggccgg ttctcccgcc
     2461 ggcaaggggt gatcgatcgt ctcgtgggcg ggacagcgcc aggcccgaac ggccgcaacg
     2521 ggcacctgac gcagacgtgc ttccatgaag gcgagccgta ggaccgacgc cgatacctcg
     2581 ccgacaccga cgacgatgcg gccgttccgt cctccgatgg cgcggttgtc gtggttgccg
     2641 cgcagcacga cgaccgggca gtcgctcccg gcggccacgg tccggctgac ggaacccagc
     2701 agtctgtcgg cgatgccgct gcggcctcgg ctgcccatga cgatcatgga tgcgttgcgc
     2761 cccgcgcaga tcagggcgtg ctcggcctcg tcgggcaccg tctcggtggt gacgacgagg
     2821 tcgggatgcc gacgcccggc acggatggcg gcggccgcga ggatgtcgtc ggcctgcatg
     2881 tcggtggagg gcttccccgg ctcacgggcg agcgcggcgc cctcgtaccg ctcccacagg
     2941 tccccgaaga ccacccagag ggggactgcg tgcagggcgg cctcgtcggc cgcccagtcg
     3001 acggctcgca ggctgggctc ggagccgtcg accccgacca ctagaggcag atacatgacg
     3061 cccctcctct cgaccgggat gcgtcaggga tgggccacga cggcgacggg ggcactgaca
     3121 cggtgcagca ccgcgtgggc gaccgcaccg atgtgcacgc cgagcgggct gggccggatg
     3181 cgccgtccga cgaccaccag ggacgcctcg tgcgacgctt cggccagaag gtcggcgggg
     3241 ctgccggggc gggatgcctc gacgacctcg acatccgggt acgactgccg ccagggcagg
     3301 agcagccggg tgaggtcggc ggccttcctg cgggccaccc cttggtccgg tacgccgccg
     3361 gcggtcagcg agggatagta cggcggtggc cgccatccgc tgaccacgtg cacggccgtg
     3421 ccgcggcgct gtgcctcgtc gaaggcgaac gagagcacgc cgtcgtcggg gctgccgatg
     3481 tcgagtccga cgacgaccgg ccggcggcgg ttggccgcgg gcggcacacc gacggaatcc
     3541 acgacgtgtt cgccggccgc ctgctcaccg gcacgtacga ggaccacggg agtctcgctg
     3601 tgggcgatca cggactgtcc gacggaaccg gccaggaagc cgccgagtcc gctgggcgcg
     3661 cgcgagccga ggaccagcag ttccgccccg tcggcgtccc tgaccagggt gtccgccggt
     3721 gggccggacc gctggtcact ggtcaccacg acaccggggt ggcgcagccg cagcccttcg
     3781 cccaccttct gcgggacacg ctcggtccag tgctggtgtg tcttcgcgcc gaggatcgaa
     3841 tcctgggcca ggaccgcggg agccggctcc cacacgtgga gcagacgtac cggcaggtcg
     3901 cgcagctcgg cctcgcgggc cgcccactcg gcggcggcgt ggctctcggg cgagccgtcg
     3961 attcccaccg tgatcgtgcg ggtcatgtcg cgcacctccc gtgtcggccc ttccgactcc
     4021 agcgtgtcgc gcaactgagc cccggggtag ggccactcgt cctcggacac ggccgagggt
     4081 cccttcggcg ggcccgtgcg gcgaaccgcg ggtcggcatg ccggaagcac cgtccgccgg
     4141 gtgccctgcg ggtgttcagt gcccctcgcc cttcagccgg tcctccgcgt gggcggcgac
     4201 gacggaggcg gccggcacga ggtccgagcc ctcgatcggc ttcaggacct gggtgaggtc
     4261 cggcatgctc gaccgcggct cccgccacgc ggtcaccccg tcccataagc cgtacgtccc
     4321 gcaggtcacg ccctcgcgtc gggcaccggc ttcgaggaca ccgaccgccg cgcggcacac
     4381 gtcttcgccc agcaggcgta cgaggcaggc gtgcggagga tcgtctacct gggtggtctg
     4441 actccgcggg gcgttcccga gcgcacgctc tcccctcacc tgcgctcccg cgcggaggtc
     4501 ggccccatct tggtccgcga cgtgttgcac tacctggccg gggcggccac catgccggac
     4561 gacatcgacc gggccttcga cgtcggcggg ccggacgtgc ccacctaccg cgagatgatg
     4621 cgccgccacg ccaccgtgag cggactccgg cggcggatca tcgtgcccgc tccggtgctc
     4681 acccccgggt tgtccagcca ctgggtcggc ctcgtcacgc cggtcccggc ctccatcgcc
     4741 cggccgctga cggagtctct gcgtcatgag gtcgtgtgcc aggagcacga catcgcccgc
     4801 tacgtccccg acgctcccgg ccggcccctg ccgttcgacg tggccctgac gctggccctg
     4861 cggcgggtcc gggaggccca ggtcgccact cgctggtcgt ccgcctccgt gccgggagcc
     4921 cccagcgatc ccctgcccac cgaccccgac tgggccggcg gcagcctcta cgaggacgag
     4981 cggcacctgc cggtcgacgc gtccccggag gcgctgtgga aggtggtgga gggcatcggc
     5041 ggggacaacg gctggtactc cttcccgccg gcctgggccg tccgcggctg gctggaccgg
     5101 ttcgtcggcg gtgtgggtct gcgccgcggc cggcgtgacg cccagcgcct gcacccggca
     5161 cgaccggtgg cgtggcgagg aggacgccgc cgaggacatc gccgcctggc gggacggacg
     5221 ggctatccgg tcgtcgacgc ggccatgcgc cagttgcgcc accagggttg gatgcacaac
     5281 cgggcacggc tgctggtggc gagcttcctg accaagacgc tgtacgtcga ctggcgcatc
     5341 ggcgcccggc acttcctgga cctcctcgtg gacggcgacg tcgtcaacaa ccagctcaac
     5401 tggcagtggg ccgccggcac cggcaccgac acccgccccc accgcgtcct caacccgctc
     5461 gtccaggcca ggcggttcga cccggacggc gtctacgtac ggcgctgggt ccccgagctc
     5521 aggagcgtgg agggcgggaa ggtgcacgaa ccctggcgcc tggcggcggc ggaacgcggt
     5581 gaactcgact acccggaccc gctcgtcgag ctcgccgacg ggctcgcgcg gttcaagcac
     5641 gcccgcggcc gggactgagg ggacgcgtcg tgcattggct cttcggcgac cagctcggcc
     5701 cccacttcct cacgccgggc gaagaggggc ccgggccgga aactccgctg ctcatgatcg
     5761 aggcgcgctc cgtcttccgg cggcggcgtt tccaccgggc caaggcccac ctggtgctgt
     5821 ccgccatgcg ccaccgcgcg gccgaaccgg gcgaccgcgt cacgtacgta cgcgccgaca
     5881 cctaccgtca gggactggcc cggaccgcgc gcgggcgccc ggtcggcgtc caccacccca
     5941 cctcgcacgc ggctctgcgc ctggtgcgcg ccctgcccca ggtgacagtg gggcccgccc
     6001 gcggcttcct cgtgccgatg accggcttcg ccgcctgggc cgagggtcac ggcggcaagc
     6061 gcctgcggca ggaggacttc taccgctggg tccgccgcgg gcacggcctg ctcatggacg
     6121 gcgagcagcc cgcggcggga cggtggaacc tcgatcacga caaccgggaa cccccgcccc
     6181 gcgaggccgc ctccctccag gtcggccgcc cgtaccggcc ccgcgaggac gacatcgacg
     6241 aagaggtccg ccacgacctc gaccgctggg aacgcgacgg ggacgtttcc ttcgtcggac
     6301 gggacggtcc ccgcctgttc cccgccaccc ggacggaggg gctgcgggca ctgcgacgct
     6361 ttgtcgaaca ccggctcgcc accttcggac cgcacgagga cgccatgctc gccgccgacc
     6421 ccgtcatgag ccacagcctc ctttcgtcca ccctgaacct cggcccgctc gacccggtcg
     6481 agtgcgtcga acgggctgag cgggcttggc gcgagggccg ggcgccgctg aacagcgtgg
     6541 agggcttcgt gcggcagatc gccggctggc gcgagtacgt ctggcagctg tactggtact
     6601 tcggcgaggg ctaccgacgc tccaacgcgc tcgggcacac cgccccgctg ccggactggt
     6661 ggaaccggct ggacgcggac gcggtccggg cgaactgcct gcgcaccgtc ctggcccagg
     6721 tccgggacac gggctggacg caccacatcc cccggctgat ggtgctcggc agtcacgcgc
     6781 tccagcgggg ctgggacccc gccgccgtca cgaactggtt ccaccgctgc ttcgtggacg
     6841 gctacgactg ggtcatgctc cccaacgtcg tcggcatgtc ccagtacgcc gacggcggcc
     6901 ggatgaccac caagccctac acctcggcgg gtgcgtacgt gaaccgcatg agcgacctct
     6961 gcggcccgtg cggctaccgg cccggcgacc gcacctgcga gcacgcgtgt ccgtacacca
     7021 ccgggtactg ggcgttcctc gaccggcacc gggagctgct ggccggcaat cagcgcgtcg
     7081 cccggccggt acggcagtcg gaccggctcg ccgacctccc ggacgtgtgc gcacagggca
     7141 cgcgcggggt gacgcaccgc catgagcccc cgccgttgcg ccgacggggt gaagtcggac
     7201 cgcaccccgt gccggaacgg gcagaagtca gtgcatccac aacagggcac ccggcggaag
     7261 cagtggcgtg cggacaaccg agagtgagaa ggggctgcgc atgcctggac tgccgccgat
     7321 ggtggccccg ccggccgaac aggtcgacga ccccgtcacc gcgaccgatg cggcgaacgc
     7381 ggtcgacgcc gtcctccggg gggtactgga cgaacggctg cgccactgcc gtgccgtcga
     7441 ccccctcttc gcccgggaac tggccgaccg tctcgcggcg ctgaccgccc ggggcggcaa
     7501 gcggctgcgc accgcgttcg cccactgcgg ctggcgcgcc gcgggcggct cgggagacgc
     7561 caccgccgtc ctgcgaacgg gagccgcgct cgaactgctc caggcgtgcg ctctggtcca
     7621 cgacgacgtg atggacggct ccgtgcagcg acgaggcgca ccggccctgc acgtcgacct
     7681 ggcccgcggg cactgggcag cgggtatgca cggctcgtcg gagtccttcg gcacctcggc
     7741 cgccgtcctc accggtgacc tggcgctcgc ctgggcggac gacctgctga ccgagacggc
     7801 actcggtacg ccgcacggcc cgcgcctgca cggggagtgg cgggcgatgc gcaccgagat
     7861 ggtcgccggc cagtaccgcg acctgcacgc gcaggcggca cggtcctccg gcgtcgacga
     7921 ggcgctggcc atcgccacct tgaagagcgc cctgtacacc gtcgcgcggc ccctcgcgct
     7981 gggagcggta ctggccggag cggccgacgg ggacgcactg gaggcgctgc gggcggccgg
     8041 ccggtgcgcc gggctggcct tccagttgcg tgacgacctc ctgggcgcct tcggcgaccc
     8101 cgcgctgacc gggaagccgg ccgacgacga cctgcgctcc cgcaagctca cctacctgct
     8161 cgccgtcgcc gtccggctcg ccgatgccgc cgatgatcac ctggcggccg cggcgctggc
     8221 tccggacgcg gacccgaagt ccgagaaggc cgtgcggcag gtgcggtccg cgctggtgcg
     8281 caccggcgcc cgggacctgg tggagacgaa gatcggggag ctgacggaca tgagcctcgc
     8341 gcacttcgac cgctgcggag cgcgcccggc cgtgcggcac gagttcgccg cactgatcgg
     8401 gcgcgcgacg ggcgcggtcc cgcgtggcac cggggaggtc gtgtgaggag ggtgccgggg
     8461 ccgaccggcc acgtcgtcgt ggtcggggcc gggctgtccg ggctggcctg cgccctgcac
     8521 ctgctggggg ccggccgccg ggtcaccgtc gtcgaacggg acgccggtcc gggcggccgg
     8581 tccggccggg tacggctggg cggttacgag ctggacaccg gtcccacggt gctgaccatg
     8641 ccgcacctgg cggacgaggc gttcgccgcc gtcggggaca gcctccgccg ccgcgtcgaa
     8701 ctgaccgcgc tggacccggc ctaccgggcc tgtttcgcgg acggttccgc actcgacgtg
     8761 cacaccgacg gcgaggcgat ggaggcggag gtgcgccgct tcgccggacc ggcgcaggcg
     8821 gccggatacc gcgatctgcg gcggtggctc gaacggctgt accgggcgca gatgcgccgc
     8881 ttcatcgaca cgaacttcga ctcccccctc caactgctgc acccggacct ggcccggctg
     8941 gcggcactgg ggggattcgg acggctggac ggccgcatcg gacgcttcct gtccgacgag
     9001 cggctgcgcc gcgtcttctc cttccaggcg ctgtacgccg gtgtggcccc ggcccgcgcc
     9061 ctcgccgcct acgcggtgat cgcgtacatg gacaccgtgg ccggcgtctg gttccccaag
     9121 ggcggcatgc acgcgctccc ccgcgccatg gccgacgcgg cggcaaccgc cggtgccgat
     9181 ctgcgctggt cggccgaagt gaaggcgctg gagcggtccg caggacgggt acgcgccgtt
     9241 cacctggcct ccggagagcg catcgcctgc gacgccgtgg tgctgacgtg cgagctgtcc
     9301 accgcctacg ggctgctggg acgggccccc cggcggccgg cccggctgcg gcactctccg
     9361 tccgccgtga tcctgcacgc gggcaccgac cgcacctggc cgcacctcgc ccaccacacc
     9421 ctctccttcg gcgccgcgtg ggagcgcacc ttcgaggaac tgacccgtac gggagaactg
     9481 atgagtgacc cctccttgct gatcacccgc cctaccacgc acgatcccgc cctggcaccg
     9541 ccggggcgcc acctccacta cgtcctcgcg ccctgtccca acacggacgt cggtccggat
     9601 gccgtcgcgt ggcgtgacct cggcccgcgc taccgcgaga gcctggtcgg cgtactggag
     9661 agccgggggc tggaggggtt cgcggacagt gtccaggagg agctcctggt gacgccgctc
     9721 gactgggacg cgcagggcca tgcggcgggc agccccttct cggtctccca caccttcgcc
     9781 cagaccggac cgttccgccc gcgcaacctc gtacgggggc tggacaacgt ggtgctcgcg
     9841 ggctgcggga ccaccccggg tgtcggcgtt ccgaccgtac tggtcagcgg caaactcgcc
     9901 gccgcgcggg tcaccggcgg tgccgggtcc cggcccgccc gcacgcgtcg gtccccggcc
     9961 gtttccgacc cgtgccccgc cccggtcccg gcaggtgccg atgacccgtc gtgaactgga
    10021 cgccgccggg atcaccgatc ccctgctgcg cgccgcctac acccggtgcc gccgtctcaa
    10081 cgcccgccac ggcaagacct acttcctggc cacccgtctg ctgccgctcg aacggcgctc
    10141 ggccgtgcac gccctgtacg gcttcgcccg ctgggcggac gacatcgtgg acgacctcga
    10201 ccggcaccgc acggccgggg aacgcgaccg tgcgctgcgc cgcctggaga gcgacctggc
    10261 cgacgggctg cgcaccggaa cgggccggga accggtggtc cgggccgtcg cggacaccgc
    10321 cgaccggtac gacatcgacc acgtgctctt cgccgacttc ctgtcctcga tgcgtgcgga
    10381 cctgaccgtc acccattacc ccacctacgc cgatctgcag gcgtacgtac acggttcggc
    10441 ggcggtcatc ggcctgcaga tgctgcccgt cctcggcacg gtcacggacc ggaaggaggc
    10501 ggcaccgcac gcggcggcgc tgggcgtggc gttccagctc accaacttcc tgcgggacgt
    10561 cggcgaggat ctcgaccgcg gccgtgtcta cctgcccggc agcctgctgg ccgcgcacgg
    10621 ggtggaccgg cccctgctgg agtggagcag gcgcaccggg cgccgcgacc gccgcatccg
    10681 ggccgctctc gtcgcggcgg aggccatgac gcggcgcgtg taccggacgg cggagccggg
    10741 catcgccatg ctcgatccac gggtgcgtcc ctgcatccgt gccgcgttca ccctctacgg
    10801 cgggattctc gacgcgatcg ccgagcagga ctacaccgtg ctgcatcgtc gcgcggtggt
    10861 gtcgcgccgg cgtcgggcgg caacggccgc cgagggtgtg ctgtgcgtgg ccgctgcccg
    10921 gtggcgtgcc cgcacctcgc cccgggtgga ggcggcgggt ggtccggcag ccgagtggca
    10981 gggaccggtg cggtgagtgg tcgacggggc ggcaggcggt ggtcgccacc cgtgcgccga
    11041 cgtggtgcgg gccccgactg ggcggctcag actccgacct ggcggcaggc gcggccctcg
    11101 ctcatcgccg acgcgctcga gcgggcctcc gcccggccct ccggcaactg gttcgtggtc
    11161 ggcgcctccc ggcaggtgcg cgcgggcgac cggccgtacg gccggacggt cggtggggtg
    11221 gaggtcgtgc tgtggcgctc ggacgacggc gagccccgtg ccggctccgg catctgcccg
    11281 cacctgggcg ctccgctgcg cgacagccgg gtggtgtgcg gcacgctggt ctgccactgg
    11341 cacgggctcg ccctggacgg ttcggcgtcc gccggctggc ggccgttccc ggtgcacgac
    11401 gacggtgtcc tcgtctgggt aaggctggac gaggtgggag gcgaggagcc caccgagcgg
    11461 cccgtcgtgc ccacgcggcc cgcgaccggc cggggggtcg actccgtgtt cacggcgacg
    11521 gggcggtgcg aaccgcagga cgtggtggcc aaccggctcg atccgtggca cggctcgtgg
    11581 ttccacccgt actcgttcgt ggacctctcg gtcgtgcggg agccgcaggg gggcgaggac
    11641 gacgctttcg tcgtcgacgt ctccttccgg gtggccgggc ggctcgtggt cccggtgcgg
    11701 gccgagttca ccgcgccgga gccacgcacg gtcgtcatgc gcatcaccga cggcgagggc
    11761 gccacgtccg tggtcgagac gcacgcgacg ccgctgaccg ggccggacca cgagcgtccc
    11821 cgcaccgccg tggtcgaggc ggtcgtcgcc gcgtcggacc ggcccggttt cgccctggca
    11881 cgggccgccg cccccgtact gcgcccgttg atgcgccgta cggccgggcg gctgtggcgc
    11941 gacgacctgg cctacgccga acggcgctgg gcactgcgca gcaccggccg gtttcccggc
    12001 tgaggacgcg ggcgccggtc agggagccga gcggtgcccc gcgacggctc cgaacgctcg
    12061 gagcacgggt gaacgacccg tccgggggac cgtccacagg acctgaccac gcactccccg
    12121 gtcggcgagc agggcgttcg cggccaggaa gccggtggtg gcggctcgtt ccatgagggc
    12181 gacgggcagg tcgcagcgga ttccgtcgcc ggccagggtc agccagggat gcggggtacg
    12241 cacggtgggg cgccgccggt gggaaccgac ctcgaacatc gggcagtccg cgcgccattc
    12301 gtgccgggcg tcgacgacgc gggcctcgcg ggtctccggg tacgcctggt gcagccggtc
    12361 gacgagctcg tcctgcacct ccttcggttc ggccgccggg tccacggcgt aggcgtgcag
    12421 ttccacgacg gatcccccgg tccgcgcggc ccagcgggcg gcctcgccct cgtaccgctc
    12481 caggacgctg acgttgtcca gtccgccgta gccgctggtg ccgaggaacc cgggccggtc
    12541 ggcgtcgacc ggccggtcga gccagagccg cgagacgagg aacggcggcg cggtgcgcag
    12601 ggcggcgatg ccgtctcgcc aggtgtcggt gcccaggccg ggtgacgcgg cgacggtctg
    12661 ccgcagcccc gcggtgtcga gggccagcac caccgcctgg tgacggtcgg caccggtgtc
    12721 cgtgagcacg tccgctcccc cgtcggcgcg gggaaggatc ccgtgcaccg gggtgccggt
    12781 gcgcacgtcg gctccgaggc gccggaggta gtcgcccagt gggttccaca gtgcctgggg
    12841 gaagggttcg accggcacgt cgaagagcag gccctcggac gatccgagga agtagatgtg
    12901 gaacatcagc agcagttccg cggcggacag ccggcgcgga tcggcgaaga agctgcggga
    12961 gaacacctcg aaggccaggt ggtgcgccgc ttcggggaag cgcacgctct ccaggaacgc
    13021 ggtggcggtg acgccgtcga agcgttcgta cacctggggc acgcgcacgt cgaggagcgg
    13081 cagggcggcc cgcgggtcca tcgcggcgag gtcgcgccat ccgaaggtgg ggctgagggc
    13141 gacgaatccg atcgcgctga ggggcggggt ccgcgggacg cgggcgaagc cgtcggtcag
    13201 gccaccgctg tgccgcaagg ggtagtcggg cagcggggtg aggcggtcca ggccggggtc
    13261 ggtacggcgg agcagtccgc ggaggttgta gtactggcgg aagaaggcgt ggaacccgcg
    13321 ggtcatggtc acggcgctgc cgtcggccag ggtggtgcgc cggccggaga gcctgccgcc
    13381 gaccgcgtcc tccttctcgt acagcgtcac gcgggcgccg cgttcggcca tgagggtggc
    13441 cgcggccaga ccggcgatcc cgccgccgat caccgcgacg gacggctcgt caccgcgtcc
    13501 gaatcggtcc gcaccgggcg cggggaagac gatctcggcc ttgcggtcgc ggccccgtcg
    13561 ggcggcggcg gtgcggcgga cggtcacagg acgcgctcct ctgtcgtggt ggggccgccg
    13621 ttgcgggcga ggaaggtgtg cacgatgccc gtctgccatc cggcgacggg ggcgacgcgc
    13681 accgaggtca ggccggcccg cgtcagccgg gcggcgaatt cgggggcggt gtcgaaggcg
    13741 acgacgctgc gccggaggtg gcggtagagg gtgcggtcgc cggtgagggt gcccgcgggg
    13801 atgacgactc cgcggcacac cgccgaccac agggcccggt gccccggcga gccgctcagg
    13861 ctgtactcgt gggcggcgaa gcgtccgccc ggcctcagga gttgccggac ggcccgcagg
    13921 accgcgtccg ggtcggtgac gttgcggaac aggtaggcgg cgaagacggc gtcgaagggg
    13981 ccttcgtcct cacgggtcgt ggcgaactcc tcggcggtca ggtggaggaa gcgcacgcgg
    14041 gcgggccacg gtttgaccag tgctcggcgc agcatgcccg cggaggcgtc cacggccgtg
    14101 atccgggctc gtggcgcggc cctgaggagg gcccgggtgg aggcgccggt accgcacccg
    14161 aggtcgagca gatgcagtcc ggctccgtcg gcggggagcg cgagacggcg ggcggaacgc
    14221 aggaggcccg tgcggtagcc ggggttcagg gccgtgaggc cgtcgtaggt gtgggaagcg
    14281 tggtcgaagg cgcgggccag gtcgtggtcg cgcaggagtg tcatcggttg ttccctccgg
    14341 ttcgggcgag gggctgggac cggcgtggca ggaagggcac ttcggccgcg gtgcgcagca
    14401 tcggccggac gggagtgcgc aacccgatgc cccactcctc ccggagggag gtcgtgccgt
    14461 cgaggaacct cagcaggcgc tcggccggga cccggcggaa caggtcggtg aagaagcgcg
    14521 gcccgtcgat gcgaccggtg tccagcgcac gcagcaggac cgcgtccatg gcccgcgccc
    14581 gtcgcccgtg cggtgccggg acgcggtcgt ggccgtcccg cagggcggcg gcgatggctc
    14641 cgctgtgccg ttgcaccgcg gcgaacgtgt agccggtggc ggggcgagtg gcaccgcccg
    14701 cggtcccgat gcggtacacg gccggcccgg cacgtcccgg gaagcgggcg tcggtcatgg
    14761 ggatgacgcc ttgttccgtc cgttccacgg tgagttcgcc cagtccgagg atgtcgcggc
    14821 agtagtgccc gagtgcggac tcgtacgcct cggtggtcag cggggcgcgg gagaactcgg
    14881 tgtactccac gagcgcccgg tccggcgcca gcggcaggac gtagccgaag gcgagtccgt
    14941 gggccggctg gggcacgcgg aagtccatca ggtccgcgac cgccgggtcg aaccggtcgg
    15001 tgcgggtgtg tacgaaccag ccgcggaagt gctgcagcag acacgtacgc gccggcggca
    15061 gctcgggaag cggccgtgag tcgaagaccc gccgggcgta cagcgtcagc ggccggcctc
    15121 cgggcagcgt gcaccggacc tccgtgcccg cgggcacggc gcgaaccgat tccgccgtac
    15181 cccgcagaag gcgcgcaccg tccgtgcggg ccaggcggcc gtggaccatc cgctcgaagt
    15241 cggcggaacg caccatgcgg taggtgaacg gggccggatc gacggtgacc gacccgccgt
    15301 cggcgccgtg cagacgcagc acggaccagg acgcgccgac cgcctcttcg aggccgtcgg
    15361 cggccgcccc ccagtagcac caggtgcgct ccgcggggcg cagcgggccg tccggcggct
    15421 cgaccagggt catggcaggg gccgtgccgt tctccgtcag ccggtgggcg aggctgagtc
    15481 cggccgcacc gccaccgatg acgagcacgt cggagtcctg ggcggaacgg ggtgtcacca
    15541 cagtcgccgt tcgacgaccg ggcttccgtc gggacccgga tgcggcggct cggcgggcgt
    15601 cggacggtcg gcgtccatca gtaccccacc accccgtcac cggccttcgc ggccgcgccg
    15661 caggcccggg cggcgcctgc caccgggtca cgcacactct tcggttccac gcttcacccc
    15721 tcgtacggac ggcgggtccg tccggtcgcc atggcttcgg gaccgaggcc gtccgtggat
    15781 gcggccgggc acgacttcgt catcggcctc acctctgcgg ttcccggtcg gcccgtacct
    15841 cccgcgccgc gcgcgtaccc gaggccagcg cgccctgtac ggagccggtc gcccggtggt
    15901 ctccgcacac gtaccggccg gggccgatgc gggtggtgcg gctcagcggc caggggggaa
    15961 gcatcgccgg cagtgcgccg tcgaccgtgc gggccgcgac ctgctcccag ccgctcgtgt
    16021 cggtgccgta cagctcggcc agccgccgga gcaccgcctg tgccctgccg ggcgggtccg
    16081 tgcccagtac ggaagtggag accagcccgg tgccgggggg cgcgtacgtg ggagcgacct
    16141 ggctgaggac gcacgtgttc aggatggctc cggtgctgtc caccatgagg atcggttcgg
    16201 ccgtcggcgg gctgtcggtg gcgtggtagt aggtggtgac ggtgcgggtg tccgggacgg
    16261 tcaggtccgg gagcagcccg gcggcggtcg ccgggtccgt cgccaccacg acgacccggg
    16321 ccggcacctc gccgccgtcc ccgagcagca ctccggcgtc cgtgatctcc gcgacgggcg
    16381 tgcccaggcg caggacgccg tcgggcaggc cgtcggccag ctgggccggt acggcgccga
    16441 tgccctccgc cggcaggcac agggatcctc ggaccatgct ccgccagacc aggtggaaga
    16501 accgggctga ggtctccagc cggtcctcca ggaagacgcc ggacaggaac ggccgtagga
    16561 tgccggcgat cgccgcgtcc gacagtccca cccgggacag ggccgccgaa gtgggacggt
    16621 cccggcgccg tcgggtgacg gccacgggca gaacggcgtc ccgtgcggtg agtgccgcca
    16681 gcgcggccag atcgcgggcc ggcagagccc gccccggcag cagcgtcccc gccgcgcggg
    16741 gctccctggt cggatcggcg aggcggacgg gcccgttcga cgtgtgggcg acgacacccg
    16801 ccgtgaacgg cctcagtcgc agactcttca gctccatgcg ccgcttcacc tgcggatagg
    16861 aggtgttgaa cacctggaac ccgcggtcca gcaggaatcc gtcccgccgg tccgtgcgca
    16921 tccggccgcc gacaccgtcg gaggcctcca gcagtgccac ccgccatccg gcgcggcaca
    16981 ggtcgagggc gcacgccagg ccggccagac ccgcgccgac gacgaccgcg tccgctgccc
    17041 ggtgttgtcc gtcgctcata tgtctcctca ctcgacgtca cgtccgtgat gcccaggggc
    17101 aaaggccggc cggtcggcct ctccgccccg gccggtgccc cggaccggtc ggcacggtcg
    17161 gggccggaag ccggtgcgag tgcggggaaa cgcccgccgg ccgacgaccg ggccacgacc
    17221 accgggtcag cggaccacgt cccccggccc atgcccaggc gccacgacca aggacggccg
    17281 gacgacaaca cctcacgggt acaccgacgg ctccagagcg gcgaccgcct cggcaagccc
    17341 cgacggacgc gccagaccgg ccaccgcctg gcccgcccat ccagggccca gggtcaggac
    17401 gacgggccgg cgccgggccc cgcgcactcc ccactccatg gcggccacgt gctgggccag
    17461 cggccggctg gcggtggtgc gggactgcga ccacagcccc accgcggcgg gcccggtcct
    17521 gcgcaccgcc gcgacgagcg actcaacggg cagcgcaccg ccgaacatcc gcaccgggac
    17581 gcctcgctcc gtgagtgcag cggacagtac ctccaacggc agagtgtggt tctcccccgg
    17641 tacgcaggcg agcaccgtgg tggaaccggg acggtcctcg accgcggggg gcgcggcgcg
    17701 gcggagcgcc ccggacacgt gccaggacag gaagtgctcg acctcgacgt acttctcgcc
    17761 ggacgtctcc cacttccggc cgactgcctg gagcgtcggc acgatcacct cggtccaggc
    17821 cgcgaccagg ccgtgttccg cgatcgcggc gagcagcagt tcgtccaagg cggaggcgtc
    17881 cagacgcagg gcggccctcg cgatcccccg gcactcctgt cgtacgtcgc ccagttgcag
    17941 gccgctgccc gcccggctcc ggcgcccggt gggagcacgt cgagccgcgt cggtgtttcg
    18001 gggcccggcc gccgtcggac gctcttcact gcgcgcgagc cgtgccgcct cggccggtgg
    18061 cagcccggtc gccgtcaggg cgcacatccg ttccagcctc gccaggtccg ccgccgtcca
    18121 gcgccggtgc cgtccgtcga cgtgcgcgtc cggccccagc ccgtaccggc ggtcccacgt
    18181 gcggaccgtg gtgggcgcca cccccagacg ccgggccacc tcgccggtgg tcaatccgcc
    18241 acggcgcgga ccgccgtcgt cgaccggctc gtcgccgtct cccgtgtacg cgttcacatg
    18301 cccactatac gacgcacaaa cgacgcatgt tgcttgcgtc gtttcctcac ccaacactgg
    18361 gaccacgcac acggcagcca cgcagggtag accggcgacg tgccgctcgg ggacggcccc
    18421 tcccgtcccc gtacgacgca cggcaggagg aacgggcatg aacacgcgta cacgaccgac
    18481 caccaccccg gtcccgcccg tggaggagac gcggtacgag gaggagctgg cgcacggcct
    18541 cgtgaaggcc gacgaggacg cgttcgcggc catctaccgg cgctgggggt cgctcgtgca
    18601 cactctggcc acccggtccc tcggcgacgc ccacgaggcg gaggacgtga ctcagcaggt
    18661 cttcgtcggc gcatggcgcg ggcggcacgg tttccggccc gagcggggca cactcggcgc
    18721 ctggctcgtc ggcatcacgc gccggaaggt cgtcgacgcg ctggccgcca ggacacggcg
    18781 cctgtcgctg gtcgagtcgg ccgggcagga catcacgccc gcccgtctcg tccagccggc
    18841 actggacgag gtactcgacc gcgtactgct cgtggaggcc ctgtcccgat tgccgcaggc
    18901 ccagcgggat gtgctgtgca tggccttcta cgaggacctg acgcaggcgc agatcgcgga
    18961 acgcacgggg gttcccctgg gcacggtcaa gagccacgcc cgccgcggcc tgcatcggct
    19021 gcgcacggcg gtcggcccgg gcgccgcaca tgacacgtgt gtctgaccgg gccggagcag
    19081 agacgccccg gggcgcatcc acggcaccgg tcgccggcga aacaccttcg agaccgccca
    19141 gcagacggaa actccctacg gaggggtgat tcccatgatg tcccggacca ccatcgccgt
    19201 cgccggctcg gccggggcct gtgccctggc cccgaccgca cccgccgcca cggctgctcc
    19261 cgagcaggcg caggacacgg gcctggtgtc cgtcttccac ggcatccccg gcacgacggt
    19321 cgacgtcttc gccaacggcg acgaaccact cggcgacttc cagcccggca cggtgaccga
    19381 aggcggcaac acgaccgtcg ccgcccatct ctccgccgac ggcaagcccc ggctgacgac
    19441 gttcaccgac gacgtctcga agacggacgc cggcaggtca cgcctcacgg tacggcacgt
    19501 cgcggcagca cccgccgtgg acgtacgggc cggcggacat cctctcttca ccggcctggc
    19561 gaacccggac gaggacaccg cgctcgtcga ggccggcatc gtgaacgccg acgtcgtgct
    19621 cgccggcacg gagacggtgg tcgtaggacc ggccggactc gacctcaagg agggcacgac
    19681 caacgtcgtc tacgcctggg gcagcgccga ggaccagact ctggctctgc ccggccaggc
    19741 cttcggcggc atggattcga cgcccctcgc ggtccacccg ggcgccggcg gcacggcagc
    19801 caccccgaac gcgtccgacc ggtggcgtgc ccgggccgcg acgccggcac gatcgcggtg
    19861 acagccgtcc tcgccgcctc gaaccggccg ccggagccca cgccggaccg cgcgaccgtg
    19921 acggcccccg tcctcacaca gtccgcgtgg agaagacgaa gcccgaggca caggagggcg
    19981 cagtgggtca cgtgcatccg tcgcacctgg tggagctggc actcggtcac gccagtggcg
    20041 aggcggacgt cggcgccctg cggcatgccg cgtcatgccc gcgctgccgc gaggaactgc
    20101 tccggttgac ccgcgtggtg accgctgcgc gcggcgcgga agcatcggac ctgccagtgc
    20161 ctccgcccga gcgcgtgtgg cagcgcatcg ccctcgaagt actcccggag accgaccggg
    20221 tgccccgtct ccgggaatcc tccgctcacg ggtccgccga cgagagggtt cgcggttccc
    20281 agcgccggtg gaccgaccac gcgggcgagg gcctcctcgg actggctctg gccatcgccg
    20341 tccttctgct ccggcggtgg cggatcaggg ccggctcggg gaactgatca ccgaggtccg
    20401 cgtctcccgc gtgcacctgt cgtcccgtcg accgccgtgc atgcagccgt tgccgcggcc
    20461 gatgtccgca ccctttccga gtccgcccgc acgtggcggc ctgtcgtgaa cggcgggttc
    20521 aagtgggcgg gtccagtccg tacagggtgc ggccgccgac cagctcccgg ccgctgacca
    20581 ggtccggcgc gatgcggacg aagacctcca cgggccaggg cacccaggaa cgaggaccgg
    20641 tgcgaacgag ttgctcgtgt tccccgggat cggtgaccac cgaggcgagg ccggtgacga
    20701 cgacgctcca gccggagtgc gtcacggcgt cgacttcgtc ggcctcgaaa gcgaccacgg
    20761 caccgtcgac ggcacggacc agctccgagg aggccgacgt gcgcaacagc acggcaccgc
    20821 tcttttccag gacgaagttg accggcagga cggcgggcag ggcgtcgcgg gtgtgcacga
    20881 tgcggcccac gggcgcgttg gccagccgct ggaggctctc ctgtcggttc agctcgcgga
    20941 atccgtcgtt gcggtacatc agccgggtgt ctctccgtgt gtcgtccggt gcgttgcgcg
    21001 tactcccatc ctgctgcccg tcggcgaccg cgacggcgag ttcggcggtg tgcggggcga
    21061 cgtgctcggc gtggtactcg acgaggccga cgccctgtcc cgcacgttcg gcgagcaggg
    21121 cccggtgccc gcgccgagcc ggcgcgcaca cggtgtccgc ggccgggccg gcggagcggg
    21181 agccggccga gaggaagcgc aggcggcggt tgtccggtga catctccgcg tagagcccct
    21241 ccagttgctc gtggtccccg gctcgacggc gcggatacgg acggtggtgc cgtccgtgag
    21301 cagcgcgtgg actgcggggc ggtgtggcgt gtcgtccttc atggcggttc tccttcgagc
    21361 cgctcgggtc ctgtgtcctg ccgagcgtcc gtcacgacgt cggacgcgcc cagggaccga
    21421 ccgggggtgc ccgcggggca cgtccggccc ccggtcttcc gccggccgtc ccgggcggcg
    21481 gcctcgggcg gtcatgtcgt gtcgggtacg accgcgaccg gacaggcgga gtggtgcaga
    21541 agggtgtggg cgacccggcc gaggcggtgc ccgaactgcc cgggacgccg ccggccgacg
    21601 accagcaggt ccgcctcgtg ggaggcggcc gacagcactc ggctacccgg tccctcggcc
    21661 gtacggcggc gcaggcgcac gtccgccggg gcgtcggcga gcgcggcctc cagctccttg
    21721 gccgcccgtt cctcgtgaag acgctcgggc gtgcccgcga gcagcgggtg gtcgaccgtg
    21781 tcgtgggtgg ggcatctcca tgcccgtacc gcgtccaggg cggcgccgcg ccgccgggcc
    21841 tcctcgcagg cgaagcgcac cgcagcggtg ggcgcgtcgg ccacacccac cacgatgcgg
    21901 ccgcgccggc cgccaccggc ggcacggtcg tcgtggtccc cccgggtcac gacgaccgga
    21961 cagtccgaca tggtggccac cgtcaggctg acggagccga gcagcaggcc ggcgagttcg
    22021 ccccgcccgc gggtgcccag gatcacggcg gacgcgttgc gcgcctcgcg caggaggacg
    22081 tactccggtt cctcggccgt cgcttcggtg gtgacggcga ggtccgggtg gtgacgacgg
    22141 gcgcgacggg tggcgacggc gaggatgtcg tcggtggtga cgtgaccgga cggcttgccg
    22201 agctcccggg cgagggaggc gccctcgtag cggtcccagc ggtaggcgtg gacgatccgc
    22261 aagggtactt cgtgcagggc ggcctcgtca gccgcccagt cgactgcccc gaggctcgac
    22321 tcggagccgt cgactccgac gaccatgggc aggtacatcg ttctcagcct cccgcgttga
    22381 gatcgaacac gatccgggcc ttgacctgtc cgccgaggac ctcgtcgatg cagtcgttga
    22441 cggcggcgag cggacgggtc tcccggatga ccttcgtgcg gccctcggcg tggagttgga
    22501 agacctcggc gagatcctgc cgggtgccga cgatggagcc gatgaccgag gtgccgttga
    22561 ggacggtgtc gaagatcggg acctggaggg tgccgtgcgc cggcagggca accatgacga
    22621 gtttcccgcc gcgccgcaga ccggagttga cggcctggaa ggcggccggg ttcaccgcga
    22681 gggcgagggc ggcgtgcgcg ccgccgtgtc gcttcagctc ggcgccgacg tcctgggtgc
    22741 gggcgtcgat gacgaggtcg gcgccgagtt cccgggcgag ttggagtttg tcgtcggtga
    22801 cgtcgatcgc gacgacccgc gctccggcga tcttcgcgta ctgcaccgcg aggtgcccca
    22861 gtccgcccac gcccgagacg gcgacgagct gggcgggccc gacttcggcg accttcagtg
    22921 ccttgtaggt ggtgacgccc gcgcaggtga gcggggcggc gtcgagggcg ctgacgccct
    22981 cgggcaccgg ctgcgcgaag tcggcccagg caagcatctt ctcggcgtac ccgccgtcgc
    23041 agccgtaccc ggtgttgacc tggtcctcgc acagggtctc ccagccggac cggcagtgct
    23101 cgcaccgccc gcacgccttg ccgagccagg gcacggcgac gcgttgtccg acggcgaggt
    23161 gggtcacgcc gtcgcccagc ttctcgacca ggccgacgcc ctcgtgcccg gggacgaacg
    23221 gcggggtggg cttgaccggc cagtcgccgt gggcggcgtg gatgtcggtg tggcacaggc
    23281 cggatgcctc gacggccacg agcacctgcc ccggaccggg ctccgggtcg ggcctgtcct
    23341 cgatgaccag gggcttgccg aactcccgga cgaccgctgc cttcatggtc ctgctccttc
    23401 tgtgctcgtc ttcggtgggc cgcgtcagtc gtgcgcgacg acggcgacgg gggtggtggc
    23461 gtggtgcatg accgcgtggg cgacggcgcc gatgtgcaca ccgaacgggc tgcggcggat
    23521 acggcggccg acgacgacga gggaggcgtc gcgggccgcg tcgatgaggt gctcggcggg
    23581 actgccgagc cggcacgtct cggtcacctc gacgtccggg tacttctccc gccagggcag
    23641 cagtgcctcg ccgagtgctt cggcctgggc gcgggccagt tcctcgcgcg ggtcgaaccc
    23701 ggcggcgatg ctgtaggtgt aggaggacgg caggttccag gccctcacgg cggtcagcgg
    23761 ggcccgccgg cgccgcgcct cctcgaaggc gaaggagagg acggcctcgt ccgggctgcc
    23821 ggtgtccagt cccacgacca cgggccggaa gcccgtggcg gcggacggga tgccggtggg
    23881 gtccttgagg tgttcgtcgg cggcctgttc ccccgcgcgg acgaggatca ccggcgtctc
    23941 ggtgcgggcg atcacggact ggccgacgga tccgaccagg aagcccgtga gcccgctgag
    24001 ggcgcgcgag ccgagcacca gcagttcggc gtcaagggtg ccggcgagca gggcgtccgc
    24061 cggattcccg gtcgcctgct cggtggtcac ctcgaccccc gggtgccgca gcctcaagcc
    24121 ctcggccgtg tcccggggga tccgttcggt ccagtgctgg tgggtctcgg cgccgaggag
    24181 cggagcctgg gccatgggct ccggtaccgg ctgccagacg tggagcagtc gtaccggcac
    24241 ccggcgcagc gtgccctcgc gggccgccca ctccgcggct gcccggctct cgggcgagcc
    24301 gtcgagtcct acggtgatcg tgcgggccat tccggccacc tcctgtgtct tctgttctgt
    24361 tctcagcgtc tcttcgggcg gtctacgggg gcaggggcct gtggtcccgg gacggggccg
    24421 accgtccctg cccgcagggt gatgggacgg gtcctcgggc gggcccgccc caccggtcgt
    24481 gttcagcgca gccacgcgtg gtcgcggacg atcgggagcc tggcccacag ccggcccagt
    24541 cccagggcgt caccggccga gacagcggcc agcgcgatca gcagcaccgc gtacagcacg
    24601 tggtagtcgg cgaacggatt cgtcgacatg ctcgccgacc cgtcggacag gtgcttcgcc
    24661 ggcggccact ccgccgccca catcagcgcc atcatcaccg tccccgccac cgcggccggc
    24721 cgcagcgcca cccccgccgt caacgccagc ccgacgccga gcaggcccag catgaacagc
    24781 cagtcggccc acgccgcccc ggcccacgag tggaacgtcg actccatcgg accgaccgcc
    24841 acgtgcccga ggaagccctc ggtcggcgaa ccaccgtcga tccagccctt gccggaggcg
    24901 gtggcgtaac cgaacccgaa cgtcttgtcc aggaacgccc acaggaagac gaagcccatc
    24961 agcacccggg ccgacgcgaa gacgaaagcc cgggcggtga gcgcgccggc ctccaccgaa
    25021 tctgccgccc ccggcacgga tacggcgccg ttacggcgcg aggacggcag gtggaaaccc
    25081 gaaccacgat gcgtggactg gtgcatggcc atgacagtga ccccttcgga gaggatgcgg
    25141 ttggttcctg acaccactca ctctcccggg ccccgccacc ccgcacccga cgccgaaagt
    25201 ccgcaccccg ggggctcaac agccccaatc cgcggggacc ttcggccggc ggtgcccgta
    25261 cggcccttac gcgcgcgtcc gcgagggccg aggcggggag gtgttcgccc acctgcccgg
    25321 ccggcctcgg acgtgggcgg gaaggaggag taaggaggag ttccgatgag ttcgtcaacc
    25381 tcgacgcccc ggtcgcggag cggctggtcg cgacggccgt ggccgcgccg tccctgcgca
    25441 ccacccagcc ctggcgcttc cggctcgata ccgacagccg cacggtgcac atccacgccg
    25501 ccgcggatcg ggcgcggcgc cacaccgacc aggtgggc
//
